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1Academic Journal
المؤلفون: Gauthier, Nicolas, Wu, Jiang Wei, Wang, Shu Pei, Allard, Pierre, Mamer, Orval A, Sweetman, Lawrence, Moser, Ann B, Kratz, Lisa, Alvarez, Fernando, Robitaille, Yves, Lépine, François, Mitchell, Grant A
المساهمون: CHU Sainte Justine Montréal, Département de Biochimie, Université de Montréal (UdeM), Goodman Cancer Research Center Montréal (GCRC), McGill University = Université McGill Montréal, Canada, Institute of Metabolic Disease, Baylor College of Medecine, The Hugo W Moser Research Institute, The Kennedy-Krieger Institute, Johns Hopkins University School of Medicine Baltimore, Armand-Frappier Santé Biotechnologie Research Centre (INRS-AFSB), Institut National de la Recherche Scientifique Québec (INRS)-Pasteur Network (Réseau International des Instituts Pasteur), Funding was provided by CIHR grant 178978 to GM (cihr-irsc.gc.ca) and Fondation Go bursary to NG (lafondationgo.com).
المصدر: ISSN: 1932-6203.
مصطلحات موضوعية: MESH: Acetyl Coenzyme A, MESH: Acyl Coenzyme A, MESH: Mice, Knockout, MESH: Animals, MESH: Mitochondria, MESH: Models, Biological, MESH: Peroxisomes, MESH: Phenotype, MESH: Pyruvic Acid, MESH: Carbon Dioxide, MESH: Gene Knockout Techniques, MESH: Humans, MESH: Gene Order, MESH: Gene Targeting, MESH: Genes, Lethal, MESH: Gluconeogenesis, MESH: Hepatocytes, MESH: Hyperammonemia, MESH: Hypoglycemia, MESH: Lethargy, MESH: Leucine, MESH: Liver, MESH: Metabolic Networks and Pathways, MESH: Metabolome, [SDV]Life Sciences [q-bio], [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
Relation: info:eu-repo/semantics/altIdentifier/pmid/23861731; PUBMED: 23861731; PUBMEDCENTRAL: PMC3702508
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2Academic Journal
المؤلفون: Boilève, Alice, Thomas, Laure, Lillo-Le Louët, Agnès, Gaboriau, Louise, Chouchana, Laurent, Ducreux, Michel, Malka, David, Boige, Valérie, Hollebecque, Antoine, Hillaire-Buys, Dominique, Jozwiak, Mathieu
المساهمون: Institut Gustave Roussy (IGR), Centre régional de pharmacovigilance CHU Henri-Mondor, CHU Henri Mondor Créteil, Centre Régional de Pharmacovigilance (CRPV), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Européen Georges Pompidou APHP (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Régional de PharmacoVigilance Nord-Pas-de-Calais CHU Lille (CRPV), Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Université de Lille-Université de Lille-Faculté de Médecine Henri Warembourg - Université de Lille, Département de Pharmacologie Clinique CHU Cochin, Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Département de médecine oncologique Gustave Roussy, Département de Pharmacologie Médicale et de Toxicologie CHRU Montpellier, Pôle Biologie-Pathologie CHRU Montpellier, Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Service de réanimation médicale polyvalente CHU Cochin, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
المصدر: ISSN: 0959-8049 ; European Journal of Cancer ; https://hal.umontpellier.fr/hal-03538025 ; European Journal of Cancer, 2020, 129, pp.32-40. ⟨10.1016/j.ejca.2020.01.019⟩.
مصطلحات موضوعية: 5-Fluorouracil, Dihydropyrimidine dehydrogenase, Encephalopathy, Hyperammonaemia, Krebs cycle, Pharmacovigilance, Rechallenge, Urea cycle, MESH: Aged, MESH: Ammonia, MESH: Urea, MESH: Antimetabolites, Antineoplastic, MESH: Brain Diseases, MESH: Citric Acid Cycle, MESH: Dose-Response Relationship, Drug, MESH: Female, MESH: Fluorouracil, MESH: France, MESH: Humans, MESH: Hyperammonemia, MESH: Incidence, MESH: Male, MESH: Middle Aged, MESH: Neoplasms, MESH: Pharmacovigilance, MESH: Retrospective Studies, MESH: Treatment Outcome, [SDV.CAN]Life Sciences [q-bio]/Cancer
Relation: info:eu-repo/semantics/altIdentifier/pmid/32120273; hal-03538025; https://hal.umontpellier.fr/hal-03538025; PUBMED: 32120273
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3
المؤلفون: Vicente C. Quintanilla, Cecilia R Giulivi, Donna F. Kusewitt, Jimi L. Brandon, Fernando Benavides, Jean Jaubert, Kirstin F. Barnhart, Irma B. Gimenez-Conti, Nancy W. Otto, Catherine Ross-Inta, John DiGiovanni, Claudio J. Conti, Carlos J. Perez, Jean-Louis Guénet, Isabelle Aubin
المساهمون: The University of Texas M.D. Anderson Cancer Center [Houston], Graduate School of Biomedical Sciences [Houston], The University of Texas Health Science Center at Houston (UTHealth)-The University of Texas M.D. Anderson Cancer Center [Houston], Génétique de la souris - Mouse Genetics, Institut Pasteur [Paris] (IP), Michale E. Keeling Center for Comparative Medicine and Research [Bastrop, Texas], School of Veterinary Medicine [Univ California Davis] (VetMed - UC Davis), University of California [Davis] (UC Davis), University of California (UC)-University of California (UC), Génétique fonctionnelle de la Souris, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Supported by National Institutes of Health grant CA90922 (C.J.C.), Department of Health and Human Services/National Cancer Institute grants P30 CA016672 (F.B. and D.F. K.) and P30 ES007784 (I.G.C.), and funding from Autism Speaks (C.G.)., We thank the Research Animal Support Facility-Smithville for their assistance with the maintenance of the mouse strains. We also thank Kevin Lin for statistical analyses, the Histology and Tissue Processing Facility Core for the IHC, and the Molecular Biology Facility Core for DNA sequencing., We are grateful to Brenda Webb (Michale E. Keeling Center) for her excellent technical skills with blood sampling. We thank Qin Sun (BCM Medical Genetics Laboratories) for the plasma amino acid analysis and ASS liver activity assays., Institut Pasteur [Paris], School of Veterinary Medicine [UC Davis], University of California-University of California, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
المصدر: American Journal of Pathology
American Journal of Pathology, 2010, 177 (4), pp.1958-1968. ⟨10.2353/ajpath.2010.100118⟩
American Journal of Pathology, American Society for Investigative Pathology, 2010, 177 (4), pp.1958-1968. ⟨10.2353/ajpath.2010.100118⟩مصطلحات موضوعية: Male, MESH: Disease Models, Animal, Cerebellum, MESH: Mice, Mutant Strains, Developmental Disabilities, Argininosuccinate synthase, MESH: Sodium Benzoate / pharmacology, MESH: Mice, Knockout, Immunoenzyme Techniques, Mice, 0302 clinical medicine, Cell Movement, Sodium Benzoate, Hyperammonemia, MESH: Animals, MESH: Syndrome, MESH: Cell Movement, Growth Disorders, Mice, Knockout, Citrullinemia, 0303 health sciences, biology, MESH: Developmental Disabilities / etiology, Syndrome, MESH: Arginine / pharmacology, MESH: Mutation, Missense / genetics, MESH: Hyperammonemia / etiology, Phenotype, MESH: Citrullinemia / etiology, 3. Good health, medicine.anatomical_structure, Urea cycle, MESH: Argininosuccinate Synthase / physiology, Female, medicine.symptom, medicine.medical_specialty, Ataxia, Urea cycle disorder, Blotting, Western, Mutation, Missense, Argininosuccinate Synthase, MESH: Developmental Disabilities / drug therapy, Arginine, Nitric Oxide, MESH: Hyperammonemia / drug therapy, MESH: Phenotype, Pathology and Forensic Medicine, 03 medical and health sciences, MESH: Mice, Inbred C57BL, Internal medicine, MESH: Growth Disorders / etiology, medicine, Animals, Humans, MESH: Blotting, Western, MESH: Growth Disorders / drug therapy, Allele, MESH: Immunoenzyme Techniques, MESH: Mice, Alleles, 030304 developmental biology, MESH: Humans, MESH: Alleles, medicine.disease, MESH: Cerebellum / abnormalities, Mice, Mutant Strains, MESH: Male, Mice, Inbred C57BL, Disease Models, Animal, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, Endocrinology, biology.protein, MESH: Nitric Oxide / metabolism, MESH: Female, MESH: Citrullinemia / drug therapy, 030217 neurology & neurosurgery, Regular Articles