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1Academic Journal
المؤلفون: Pillay, Nisha, Mariotti, Laura, Zaleska, Mariola, Inian, Oviya, Jessop, Matthew, Hibbs, Sam, Desfosses, Ambroise, Hopkins, Paul, Templeton, Catherine, Beuron, Fabienne, Morris, Edward, Guettler, Sebastian
المساهمون: The Institute of Cancer Research (ICR), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Groupe Imagerie microscopique d'assemblages complexes / Microscopic Imaging of complex Assemblies group (IBS MICA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Diamond Light Source for the cryo-EM facilities at the UK's national Electron Bio-imaging Centre, ICR Light Microscopy Facility, European Project: C47521/A16217, European Project: C47521/A28286, European Project: EM28549,eBIC
المصدر: ISSN: 0028-0836.
مصطلحات موضوعية: MESH: beta Catenin, MESH: Cryoelectron Microscopy, MESH: Polymerization, MESH: Tankyrases, MESH: Enzyme Activation, MESH: Biocatalysis, MESH: Catalytic Domain, MESH: Wnt Signaling Pathway, MESH: Amino Acid Motifs, [SDV]Life Sciences [q-bio]
Relation: info:eu-repo/semantics/altIdentifier/pmid/36418402; info:eu-repo/grantAgreement//C47521/A16217/EU/Cancer Research UK, initially through a Career Establishment Award/; info:eu-repo/grantAgreement//C47521/A28286/EU/Cancer Research UK, through a Programme Foundation Award/; info:eu-repo/grantAgreement//EM28549/EU/Wellcome Trust, MRC and BBRSC/eBIC; PUBMED: 36418402; PUBMEDCENTRAL: PMC9712121
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2Academic Journal
المؤلفون: Drula, Elodie, Garron, Marie-Line, Dogan, Suzan, Lombard, Vincent, Henrissat, Bernard, Terrapon, Nicolas
المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Biodiversité et Biotechnologie Fongiques (BBF), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
المصدر: ISSN: 0305-1048.
مصطلحات موضوعية: MESH: Carbohydrates, MESH: Databases, Nucleic Acid, Protein, MESH: Enzyme Activation, MESH: Enzymes, MESH: Humans, [SDV]Life Sciences [q-bio]
Relation: info:eu-repo/semantics/altIdentifier/pmid/34850161; hal-03588994; https://amu.hal.science/hal-03588994; https://amu.hal.science/hal-03588994/document; https://amu.hal.science/hal-03588994/file/gkab1045.pdf; PUBMED: 34850161; PUBMEDCENTRAL: PMC8728194; WOS: 000743496700069
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3Academic Journal
المؤلفون: Fernández-Lucas, Jesús, Acebrón, Iván, Wu, Ruiying, Alfaro, Yohana, Acosta, Javier, Kaminski, Pierre-Alexandre, Arroyo, Miguel, Joachimiak, Andrzej, Nocek, Boguslaw, de La Mata, Isabel, Mancheño, José
المساهمون: Universidad Europea de Madrid = European University of Madrid (UEM), Universidad de la Costa = University of la Costa (Unicosta), Instituto de Química Física Rocasolano (IQFR), Consejo Superior de Investigaciones Cientificas España = Spanish National Research Council Spain (CSIC), Argonne National Laboratory Lemont (ANL), Universidad Complutense de Madrid = Complutense University of Madrid Madrid (UCM), Biologie des Bactéries pathogènes à Gram-positif, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), University of Chicago, This work was supported by grants CTQ2009-11543 (IDLM), PID2020-117025RB-I00 (JF-L) and AGL2017-84614-C2-2-R (JMM) from the Spanish Ministry of Science and Innovation, S2009/PPQ-1752 (IDLM) from Comunidad Autónoma de Madrid and XSAN192006 (IDLM) from the Santander Foundation. This research was funded in part by National Institutes of Health grant (GM115586 to AJ). The use of SBC beamlines at the Advanced Photon Source is supported by the U.S. Department of Energy (DOE) Office of Science and operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357 (AJ).
المصدر: ISSN: 0141-8130 ; International Journal of Biological Macromolecules ; https://pasteur.hal.science/pasteur-03549990 ; International Journal of Biological Macromolecules, 2021, 192, pp.138-150. ⟨10.1016/j.ijbiomac.2021.09.164⟩.
مصطلحات موضوعية: 2′-Deoxyribosyltransferases, Crystal structure, Psychrophilic enzymes, MESH: Adaptation, Physiological, MESH: Bacterial Proteins, MESH: Disulfides, MESH: Enzyme Activation, MESH: Enzyme Stability, MESH: Models, Molecular, MESH: Pentosyltransferases, MESH: Protein Conformation, MESH: Protein Multimerization, MESH: Recombinant Proteins, MESH: Spectrum Analysis, MESH: Thermodynamics, MESH: Catalytic Domain, MESH: Chemical Phenomena, MESH: Cold Temperature, [SDV]Life Sciences [q-bio]
Relation: info:eu-repo/semantics/altIdentifier/pmid/34624379; pasteur-03549990; https://pasteur.hal.science/pasteur-03549990; https://pasteur.hal.science/pasteur-03549990/document; https://pasteur.hal.science/pasteur-03549990/file/1-s2.0-S0141813021020924-main.pdf; PUBMED: 34624379
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4Academic Journal
المساهمون: Unité de Biothérapies anti-Infectieuses et Immunité Brétigny-sur-Orge, Institut de Recherche Biomédicale des Armées Brétigny-sur-Orge (IRBA), Pathogénie des Toxi-infections bactériennes, Institut Pasteur Paris (IP), Service de Pharmacologie et Immunoanalyse (SPI), Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), École du Val de Grâce (EVDG), Service de Santé des Armées, National Reference Center for Anthrax Brétigny-sur-Orge (CNR-LE Charbon), This work was funded by the Joint Ministerial Program of R&D against CBRNE risks (NRBC H1.11).
المصدر: ISSN: 0022-1899.
مصطلحات موضوعية: bacteria, blood, inhalational anthrax, mice, toxins, MESH: Animals, Outbred Strains, MESH: Bacterial Toxins, MESH: Biomarkers, MESH: Disease Models, Animal, MESH: Enzyme Activation, MESH: Enzyme Assays, MESH: Female, MESH: Mice, MESH: Nasal Absorption, MESH: Virulence, MESH: Virulence Factors, MESH: Anthrax, MESH: Antigens, Bacterial, MESH: Bacillus anthracis, MESH: Bacteremia, [SDV]Life Sciences [q-bio], [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Relation: info:eu-repo/semantics/altIdentifier/pmid/31574153; pasteur-03293185; https://pasteur.hal.science/pasteur-03293185; https://pasteur.hal.science/pasteur-03293185/document; https://pasteur.hal.science/pasteur-03293185/file/jiz497.pdf; PUBMED: 31574153; PUBMEDCENTRAL: PMC6996859; WOS: 000518533500022
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5Academic Journal
المؤلفون: Caval, Vincent, Jiao, Wenjuan, Berry, Noémie, Khalfi, Pierre, Pitré, Emmanuelle, Thiers, Valérie, Vartanian, Jean Pierre, Wain-Hobson, Simon, Suspene, Rodolphe
المساهمون: Rétrovirologie moléculaire - Molecular Retrovirology, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7), Université Sorbonne Paris Cité (USPC), ED 515 - Complexité du vivant, Sorbonne Université (SU), This work was supported by grants from the Institut Pasteur and Centre National de la Recherche Scientifique (CNRS). NB and EP were supported by Allocations de Recherche du Ministère de la Recherche while PK was supported by La Ligue contre le Cancer. WJ was supported by China Scholarship Council., We would like to thank Yu Wei for mouse samples.
المصدر: ISSN: 1471-2164 ; BMC Genomics ; https://pasteur.hal.science/pasteur-02545764 ; BMC Genomics, 2019, 20 (1), pp.858. ⟨10.1186/s12864-019-6216-x⟩.
مصطلحات موضوعية: Cytidine deaminase, Cancer, APOBEC1, Nuclear DNA, Somatic mutations, MESH: APOBEC-1 Deaminase/chemistry, MESH: APOBEC-1 Deaminase/genetics, MESH: Animals, MESH: Base Sequence, MESH: Chromosomes, Mammalian/genetics, MESH: DNA Breaks, Double-Stranded, MESH: DNA, Single-Stranded, MESH: Enzyme Activation, MESH: Gene Expression, MESH: Mice, MESH: Mutation, MESH: Phylogeny, MESH: RNA Editing, MESH: Substrate Specificity, MESH: APOBEC-1 Deaminase/metabolism, MESH: Amino Acid Sequence, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]
Relation: info:eu-repo/semantics/altIdentifier/pmid/31726973; pasteur-02545764; https://pasteur.hal.science/pasteur-02545764; https://pasteur.hal.science/pasteur-02545764/document; https://pasteur.hal.science/pasteur-02545764/file/Mouse%20APOBEC1%20cytidine%20deaminase.pdf; PUBMED: 31726973; PUBMEDCENTRAL: PMC6854741
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6
المؤلفون: Nisha Pillay, Laura Mariotti, Mariola Zaleska, Oviya Inian, Matthew Jessop, Sam Hibbs, Ambroise Desfosses, Paul C. R. Hopkins, Catherine M. Templeton, Fabienne Beuron, Edward P. Morris, Sebastian Guettler
المساهمون: The Institute of Cancer Research (ICR), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Diamond Light Source for the cryo-EM facilities at the UK's national Electron Bio-imaging Centre, ICR Light Microscopy Facility, European Project: C47521/A16217, European Project: C47521/A28286, European Project: EM28549,eBIC
المصدر: Nature
Nature, 2022, 612 (7938), pp.162-169. ⟨10.1038/s41586-022-05449-8⟩مصطلحات موضوعية: Tankyrases, MESH: Enzyme Activation, Multidisciplinary, [SDV]Life Sciences [q-bio], Cryoelectron Microscopy, Amino Acid Motifs, MESH: beta Catenin, MESH: Wnt Signaling Pathway, MESH: Catalytic Domain, Polymerization, Enzyme Activation, MESH: Amino Acid Motifs, MESH: Polymerization, Catalytic Domain, Biocatalysis, MESH: Cryoelectron Microscopy, MESH: Tankyrases, Wnt Signaling Pathway, MESH: Biocatalysis, beta Catenin
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7Academic Journal
المؤلفون: Maillet, Vanessa, Boussetta, Nadia, Leclerc, Jocelyne, Fauveau, Veronique, Foretz, Marc, Viollet, Benoit, Couty, Jean-Pierre, Celton-Morizur, Séverine, Perret, Christine, Desdouets, Chantal
المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Sorbonne Paris Cité (USPC), Université Paris Diderot - Paris 7 (UPD7), This study was supported by grants from INSERM, Agence Nationale de la Recherche (ANR-2010-BLANC-1123-02). V.M. was a recipient of a La Ligue Nationale Contre le Cancer (LNCC) grant., ANR-10-BLAN-1123,AMPLOI,Thérapeutique des désordres métaboliques hépatiques: activation de l'AMPK et contrôle de la ploidie hépatocytaire(2010)
المصدر: ISSN: 2211-1247.
مصطلحات موضوعية: polyploidy, mitosis fidelity, microtubule spindle, liver regeneration, hepatocytes, LKB1, EGFR, MESH: Animals, MESH: Cell Proliferation, MESH: Liver, MESH: Liver Regeneration, MESH: Mice, MESH: Mitosis, MESH: Ploidies, MESH: Protein-Serine-Threonine Kinases, MESH: Signal Transduction, MESH: Enzyme Activation, MESH: ErbB Receptors, MESH: Gene Deletion, MESH: Gene Silencing, MESH: Genome, MESH: Hepatocytes, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism
Relation: info:eu-repo/semantics/altIdentifier/pmid/29466728; inserm-02349915; https://inserm.hal.science/inserm-02349915; https://inserm.hal.science/inserm-02349915/document; https://inserm.hal.science/inserm-02349915/file/CellReport2018%20Maillet.pdf; PUBMED: 29466728
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8Academic Journal
المؤلفون: Htoo, Htut Htut, Limsuvan, Suveerawan, Thamsermsang, Onusa, Hernandez, Jean-François, Checler, Frédéric, Govitrapong, Piyarat, Pakaprot, Narawut, Akarasereenont, Pravit, Vincent, Bruno
المساهمون: Mahidol University Bangkok, Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS), Excellence Laboratory LabEx DISTALZ, Centre National de la Recherche Scientifique (CNRS), ANR-10-LABX-0045,COTE,COntinental To coastal Ecosystems: evolution, adaptability and governance(2010), ANR-11-LABX-0009,DISTALZ,Développement de stratégies innovantes pour une approche transdisciplinaire de la maladie d'Alzheime(2011)
المصدر: ISSN: 1932-6203.
مصطلحات موضوعية: MESH: Amyloid Precursor Protein Secretases, MESH: Animals, MESH: Cell Line, MESH: Enzyme Activation, MESH: Herbal Medicine, MESH: Humans, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Relation: info:eu-repo/semantics/altIdentifier/pmid/28107420; PUBMED: 28107420; PUBMEDCENTRAL: PMC5249131
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9Academic Journal
المؤلفون: Lévêque, Christian, Ferracci, Géraldine, Maulet, Yves, Mazuet, Christelle, Popoff, Michel, Blanchard, Marie-Pierre, Seagar, Michael, El Far, Oussama
المساهمون: Unité de Neurobiologie des canaux Ioniques et de la Synapse (UNIS - Inserm U1072), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en neurobiologie - neurophysiologie de Marseille (CRN2M), Centre National de Référence des Bactéries Anaérobies et Botulisme - National Reference Center Anaerobic Bacteria and Botulism (CNR), Institut Pasteur Paris (IP), This work was supported by INSERM, CNRS and a grant from the DGA (REI N° 0634040)
المصدر: ISSN: 2045-2322.
مصطلحات موضوعية: MESH: Antibodies, Monoclonal/immunology, MESH: Biosensing Techniques, MESH: Humans, MESH: Kinetics, MESH: Lab-On-A-Chip Devices, MESH: Microchip Analytical Procedures, MESH: Sensitivity and Specificity, MESH: Substrate Specificity, MESH: Botulinum Toxins*/immunology, MESH: Botulinum Toxins, Type A*/immunology, MESH: Enzyme Activation, MESH: Epitopes/immunology, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, [SDV.TOX]Life Sciences [q-bio]/Toxicology, [SDV]Life Sciences [q-bio], [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Relation: info:eu-repo/semantics/altIdentifier/pmid/26648139; inserm-01708826; https://www.hal.inserm.fr/inserm-01708826; https://www.hal.inserm.fr/inserm-01708826/document; https://www.hal.inserm.fr/inserm-01708826/file/srep17953.pdf; PUBMED: 26648139; PUBMEDCENTRAL: PMC4673697
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10Academic Journal
المؤلفون: Saraceno, Claudia, Marcello, Elena, Di Marino, Daniele, Borroni, Barbara, Claeysen, Sylvie, Perroy, Julie, Padovani, Alessandro, Tramontano, Anna, Gardoni, Fabrizio, Di Luca, Monica
المساهمون: Department of Pharmacological Sciences and Biomolecular, Università degli Studi di Milano = University of Milan (UNIMI), Dipartimento di Fisica Roma La Sapienza, Università degli Studi di Roma "La Sapienza" = Sapienza University Rome (UNIROMA), Università degli Studi di Brescia = University of Brescia (UniBs), Institut de Génomique Fonctionnelle (IGF), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Pasteur Network (Réseau International des Instituts Pasteur), Acknowledgement is made to the donors of the ADR, a program of the BrightFocus Foundation, for support of this research. This work was supported by grants from the European Union's Seventh Framework Program (FP7 2007-2013, Grant Agreement no. PIAP-GA-2008-217902) (to MdL), from Fondazione CARIPLO (project no. 2319-2008) (to MdL), from FIRB-Accordi di Programma (project code RBAP11HSZS) (to MdL), from PRIN 2010PWNJXK (to MdL), from Veronesi Foundation Young Investigator Research Programme 2013 (to EM), from the Alzheimer's Association (NIRP-14-304969) (to EM) and an ADR program research fellowship (to EM). SC acknowledges support from the France Alzheimer Association, the Languedoc Roussillon Region and the French Research National Agency ANR (ANR-12-BSV4-008-01 ADAMGUARD project)., ANR-12-BSV4-0008,ADAMGUARD,Les réseaux protéiques associés aux récepteurs 5 HT4 : gardes rapprochées du trafic de l'ADAM10 et de l'APP(2012), European Project: 217902,EC:FP7:PEOPLE,FP7-PEOPLE-2007-3-1-IAPP,CPADS(2008)
المصدر: ISSN: 2041-4889 ; Cell Death and Disease ; https://riip.hal.science/pasteur-01203115 ; Cell Death and Disease, 2014, 5, pp.e1547. ⟨10.1038/cddis.2014.492⟩.
مصطلحات موضوعية: MESH: ADAM Proteins, MESH: Adaptor Proteins, Signal Transducing, MESH: Synapses, MESH: Amino Acid Sequence, MESH: COS Cells, MESH: Amyloid Precursor Protein Secretases, MESH: Animals, MESH: Cercopithecus aethiops, MESH: HEK293 Cells, MESH: Enzyme Activation, MESH: Golgi Apparatus, MESH: Humans, MESH: Molecular Sequence Data, MESH: Membrane Proteins, MESH: Models, Molecular, MESH: Phosphorylation, MESH: Protein Binding, MESH: Phosphothreonine, MESH: Post-Synaptic Density, MESH: Protein Kinase C, MESH: Alzheimer Disease, MESH: Rats, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/25429624; info:eu-repo/grantAgreement/EC/FP7/217902/EU/Cell permeable peptides as drug delivery system: a way towards innovative therapeutic strategies for neurodegeneration/CPADS; PUBMED: 25429624; PUBMEDCENTRAL: PMC4260750
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11Academic Journal
المؤلفون: Antoine, Francis, Girard, Denis
المساهمون: Armand-Frappier Santé Biotechnologie Research Centre (INRS-AFSB), Institut National de la Recherche Scientifique Québec (INRS)-Pasteur Network (Réseau International des Instituts Pasteur), The study was partially supported by the Natural Sciences and Engineering Research Council of Canada (NSERC).
المصدر: ISSN: 1547-691X.
مصطلحات موضوعية: inflammation, zymography, granulocytes, flow cytometry, Degranulation, MESH: Anti-Inflammatory Agents, Non-Steroidal, MESH: Cell Degranulation, MESH: Signal Transduction, MESH: p38 Mitogen-Activated Protein Kinases, MESH: Cells, Cultured, MESH: Curcumin, MESH: Enzyme Activation, MESH: Humans, MESH: Matrix Metalloproteinase 9, MESH: N-Formylmethionine Leucyl-Phenylalanine, MESH: Neutrophils, MESH: Secretory Vesicles, [SDV.TOX]Life Sciences [q-bio]/Toxicology
Relation: info:eu-repo/semantics/altIdentifier/pmid/24926560; PUBMED: 24926560
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12
المؤلفون: Javier Acosta, Jesús Fernández-Lucas, Miguel Arroyo, Pierre Alexandre Kaminski, Iván Acebrón, Andrzej Joachimiak, José M. Mancheño, Boguslaw Nocek, Isabel de la Mata, Yohana Alfaro, Ruiying Y. Wu
المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Comunidad de Madrid, Fundación Banco Santander, National Institutes of Health (US), Department of Energy (US), Argonne National Laboratory (US), Universidad Europea de Madrid = European University of Madrid (UEM), Universidad de la Costa (CUC), Instituto de Química Física Rocasolano (IQFR), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Argonne National Laboratory [Lemont] (ANL), Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM), Biologie des Bactéries pathogènes à Gram-positif, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), University of Chicago, This work was supported by grants CTQ2009-11543 (IDLM), PID2020-117025RB-I00 (JF-L) and AGL2017-84614-C2-2-R (JMM) from the Spanish Ministry of Science and Innovation, S2009/PPQ-1752 (IDLM) from Comunidad Autónoma de Madrid and XSAN192006 (IDLM) from the Santander Foundation. This research was funded in part by National Institutes of Health grant (GM115586 to AJ). The use of SBC beamlines at the Advanced Photon Source is supported by the U.S. Department of Energy (DOE) Office of Science and operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357 (AJ).
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
REDICUC-Repositorio CUC
Corporación Universidad de la Costa
instacron:Corporación Universidad de la Costa
E-Prints Complutense. Archivo Institucional de la UCM
'International Journal of Biological Macromolecules ', vol: 192, pages: 138-150 (2021)
International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, 2021, 192, pp.138-150. ⟨10.1016/j.ijbiomac.2021.09.164⟩مصطلحات موضوعية: Models, Molecular, MESH: Enzyme Stability, Chemical Phenomena, Protein Conformation, MESH: Cold Temperature, [SDV]Life Sciences [q-bio], MESH: Catalytic Domain, MESH: Spectrum Analysis, Biochemistry, Nucleobase, MESH: Recombinant Proteins, MESH: Protein Conformation, Structural Biology, Catalytic Domain, Enzyme Stability, Moiety, Disulfides, Structural motif, Psychrophile, MESH: Bacterial Proteins, MESH: Pentosyltransferases, chemistry.chemical_classification, biology, MESH: Protein Multimerization, Chemistry, General Medicine, Adaptation, Physiological, Recombinant Proteins, Cold Temperature, Psychrophilic enzymes, Crystal structures, Thermodynamics, MESH: Thermodynamics, MESH: Models, Molecular, Mesophile, Bioquímica, MESH: Enzyme Activation, Stereochemistry, Cleavage (embryo), Bacterial Proteins, MESH: Disulfides, 2′-Deoxyribosyltransferases, Pentosyltransferases, Molecular Biology, Spectrum Analysis, Crystal structure, MESH: Chemical Phenomena, Glycosidic bond, biology.organism_classification, MESH: Adaptation, Physiological, Enzyme Activation, Protein Multimerization, Bacteria
وصف الملف: 13 páginas; application/pdf
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13Academic Journal
المؤلفون: Walser, Romy, Burke, John, E., Gogvadze, Elena, Bohnacker, Thomas, Zhang, Xuxiao, Hess, Daniel, Küenzi, Peter, Leitges, Michael, Hirsch, Emilio, Williams, Roger, L., Laffargue, Muriel, Wymann, Matthias, P.
المساهمون: Department of Biomedicine, Laboratory of Molecular Biology, Medical Research Council, Friedrich Miescher Institute for Biomedical Research, Biotechnology center of Oslo, Faculty of Medicine Oslo, University of Oslo (UiO)-University of Oslo (UiO)-Rigshospitalet Copenhagen, Copenhagen University Hospital-Copenhagen University Hospital, Department of Genetics, Biology and Biochemistry, Università degli studi di Torino = University of Turin (UNITO), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by the Swiss National Science Foundation (310030_127574 & 31EM30-126143, www.snf.ch), the ESF EuroMEMBRANE programme grant FP-018 (www.esf.org), and the Medical Research Council (file reference number U105184308). JEB was supported by an EMBO long-term fellowship (ALTF268-2009, www.embo.org) and the British Heart Foundation (PG11/109/29247, www.bhf.org.uk).
المصدر: ISSN: 1544-9173.
مصطلحات موضوعية: MESH: Animals, MESH: Calcium, MESH: Mice, Inbred C57BL, MESH: Models, Biological, Molecular, MESH: Phosphorylation, MESH: Phosphoserine, MESH: Protein Binding, MESH: Protein Kinase C beta, MESH: Protein Structure, Tertiary, MESH: Receptors, G-Protein-Coupled, MESH: Signal Transduction, MESH: Catalytic Domain, MESH: Thapsigargin, MESH: Cell Degranulation, MESH: Class Ib Phosphatidylinositol 3-Kinase, MESH: Enzyme Activation, MESH: Enzyme Stability, MESH: Extracellular Space, MESH: Mast Cells, [SDV.BC]Life Sciences [q-bio]/Cellular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/23824069; inserm-01055308; https://inserm.hal.science/inserm-01055308; https://inserm.hal.science/inserm-01055308/document; https://inserm.hal.science/inserm-01055308/file/journal.pbio.1001587.pdf; PUBMED: 23824069
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14Academic Journal
المؤلفون: Amiable, Claire, Pochet, Sylvie, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre
المساهمون: Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was financially supported by the Institut Pasteur, CNRS, Fondation pour la Recherche Medicale (DCM20111223063 to S. Pochet) and by the French Infrastructure for Integrated Structural Biology (FRISBI) ANR-10-INSB-05-01. C. Amiable was recipient of a fellowship from the French Ministry of Research., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)
المصدر: ISSN: 1932-6203.
مصطلحات موضوعية: MESH: Adenosine Monophosphate/analogs & derivatives, MESH: Adenosine Monophosphate/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Binding, MESH: Adenosine Monophosphate/metabolism, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/genetics, MESH: Proto-Oncogene Proteins/metabolism, MESH: Rats, MESH: Sequence Alignment, MESH: Thermodynamics, MESH: Adenosine Monophosphate/pharmacology, MESH: Models, Molecular, MESH: Amino Acid Sequence, MESH: Animals, MESH: Catalytic Domain, MESH: Enzyme Activation/drug effects, MESH: Humans, MESH: Kinetics, MESH: Molecular Conformation, MESH: Molecular Sequence Data, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/genetics, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/genetics, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/24260472; PUBMED: 24260472
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15Academic Journal
المؤلفون: Fraternale, Alessandra, Crinelli, Rita, Casabianca, Anna, Paoletti, Maria Filomena, Orlandi, Chiara, Carloni, Elisa, Smietana, Michaël, Palamara, Anna Teresa, Magnani, Mauro
المساهمون: Department of Biomolecular Sciences, Università degli Studi di Urbino 'Carlo Bo', Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), San Raffaele Pisana Scientific Institute for Resaearch, Hospitalisation, and Health Care, Department of Public Health and Infectious Diseases, Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Università degli Studi di Roma "La Sapienza" = Sapienza University Rome (UNIROMA), This work was supported by the FIRB (Investment fund of basic research) Project 2006 Idee Progettuali (RBIP067F9E 007, PRIN (Research projects of national interest) 2008 prot. 2008BP25KN_001 granted to M. Magnani and PRIN (Research projects of national interest) 2010-2011-prot. 2010PHT9NF_004 granted to A. Fraternale.
المصدر: ISSN: 1932-6203.
مصطلحات موضوعية: MESH: Acetylcysteine, MESH: Animals, MESH: Cysteamine, MESH: Enzyme Activation, MESH: Female, MESH: Glutathione, MESH: Interferon Regulatory Factor-1, MESH: Interleukin-12 Subunit p40, MESH: Interleukin-27, MESH: Macrophages, MESH: Mice, MESH: NF-kappa B, MESH: Phosphorylation, MESH: STAT1 Transcription Factor, MESH: Signal Transduction, MESH: Sulfhydryl Compounds, MESH: Cell Line, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/23536773; PUBMED: 23536773
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16Academic Journal
المؤلفون: Deng, Xuefeng, Dong, Yanming, Yi, Qianhui, Huang, Yu, Zhao, Dan, Yang, Yongbo, Tijssen, Peter, Qiu, Jianming, Liu, Kaiyu, Li, Yi
المساهمون: College of Life Sciences, Central China Normal University Wuhan, China, Armand-Frappier Santé Biotechnologie Research Centre (INRS-AFSB), Institut National de la Recherche Scientifique Québec (INRS)-Pasteur Network (Réseau International des Instituts Pasteur), Department of Microbiology, Molecular genetics and Immunology, University of Kansas Medical Center Kansas City, KS, USA, Bioengineering Department, Wuhan Bioengineering Institute, This work was funded by the National Natural Science Foundation of China (30670081) (http://www.nsfc.gov.cn/Portal0/default166.htm).
المصدر: ISSN: 1932-6203.
مصطلحات موضوعية: MESH: Amino Acid Motifs, MESH: Amino Acid Substitution, MESH: Humans, MESH: Models, Molecular, MESH: Mutation, MESH: NF-kappa B/metabolism, MESH: Parvovirus B19, Human/enzymology, Human/genetics, MESH: Phospholipases A2/chemistry, MESH: Phospholipases A2/genetics, MESH: Phospholipases A2/metabolism, MESH: Pregnancy, MESH: Capsid Proteins/genetics, MESH: Protein Conformation, MESH: Protein Transport, MESH: Signal Transduction, MESH: Transcriptional Activation, MESH: Tumor Necrosis Factor-alpha/metabolism, MESH: Capsid Proteins/metabolism, MESH: Cell Membrane/metabolism, MESH: Cells, Cultured, MESH: Consensus Sequence, MESH: Enzyme Activation/genetics, MESH: Erythema Infectiosum, MESH: Female, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/23596524; PUBMED: 23596524; PUBMEDCENTRAL: PMC3626588
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17
المؤلفون: Chandini Bhaskar Naidu, Joanna Timmins, Fabienne Hans, Muge Senarisoy
المساهمون: Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 9226, p 9226 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩مصطلحات موضوعية: DNA Repair, Review, lcsh:Chemistry, chemistry.chemical_compound, 0302 clinical medicine, MESH: Structure-Activity Relationship, Neoplasms, MESH: Molecular Targeted Therapy, inhibitors, MESH: Animals, MESH: Neoplasms, Molecular Targeted Therapy, MESH: DNA Glycosylases, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, MESH: DNA Repair, 0303 health sciences, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], MESH: Gene Expression Regulation, Enzymologic, General Medicine, Base excision repair, 3. Good health, Computer Science Applications, DNA glycosylases, 030220 oncology & carcinogenesis, Disease Susceptibility, MESH: Enzyme Activation, DNA repair, MESH: Disease Susceptibility, Antineoplastic Agents, Biology, base excision repair, Catalysis, Gene Expression Regulation, Enzymologic, Inorganic Chemistry, 03 medical and health sciences, Structure-Activity Relationship, medicine, Animals, Humans, cancer, Physical and Theoretical Chemistry, Molecular Biology, 030304 developmental biology, MESH: DNA Damage, MESH: Humans, drug resistance, Mechanism (biology), Organic Chemistry, Cancer, medicine.disease, Enzyme Activation, Enzyme, chemistry, lcsh:Biology (General), lcsh:QD1-999, DNA glycosylase, Cancer cell, Cancer research, MESH: Antineoplastic Agents, DNA, DNA Damage
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18Academic Journal
المؤلفون: Amoasii, Leonela, Bertazzi, Dimitri, L., Tronchère, Hélène, Hnia, Karim, Chicanne, Gaëtan, Rinaldi, Bruno, Cowling, Belinda, S., Ferry, Arnaud, Klaholz, Bruno, Payrastre, Bernard, Laporte, Jocelyn, Friant, Sylvie
المساهمون: Médecine translationnelle et neurogénétique, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Génétique moléculaire, génomique, microbiologie (GMGM), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche en myologie, Université Pierre et Marie Curie - Paris 6 (UPMC)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Biologie structurale intégrative, Service Hématologie - IUCT-Oncopole CHU Toulouse, Pôle Biologie CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle IUCT CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), This work was supported by grants from INSERM, Collège de France (to JL and fellowship to BSC), CNRS ATIP-05-00932 and ATIP-Plus-08-3098 to SF), Université de Strasbourg, the Association Française contre les Myopathies (AFM grant to JL and fellowship to DLB), Fondation Recherche Médicale (FRM DEQ20071210538 to JL, INE20051105238 and FRM-Comité Alsace 2006CX67-1 to SF), Association pour la Recherche sur le Cancer (ARC JR/MLD/MDV-CR306/7901 to SF), Agence Nationale de la Recherche (ANR-07-BLAN-0065 to JL, BP, HT, GC, and SF), the E-rare program to JL, GC, BP, and HT, and a BDI-CNRS Région Alsace fellowship to LA., ANR-07-BLAN-0065,PHOSPHOINOPATHO,Roles of the phosphoinositides PtdIns3P, PtdIns(3,5)P2 and PtdIns5P in cell signalling and trafficking, implication in human disease.(2007)
المصدر: ISSN: 1553-7390.
مصطلحات موضوعية: MESH: Animals, MESH: Desmin, MESH: Muscle, Skeletal, MESH: Mutation, MESH: Myopathies, Structural, Congenital, MESH: Phenotype, MESH: Phosphatidylinositol Phosphates, MESH: Phosphoric Monoester Hydrolases, MESH: Protein Tyrosine Phosphatases, Non-Receptor, MESH: Saccharomyces cerevisiae, MESH: Disease Models, Animal, MESH: Enzyme Activation, MESH: Gene Expression, MESH: Humans, MESH: Male, MESH: Mice, Knockout, MESH: Muscle Strength, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/23071445; PUBMED: 23071445
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19Academic Journal
المؤلفون: Vallée, Béatrice, Doudeau, Michel, Godin, Fabienne, Gombault, Aurélie, Tchalikian-Cosson, Aurélie, de Tauzia, Marie-Ludivine, Bénédetti, Hélène
المساهمون: Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)
المصدر: ISSN: 1932-6203.
مصطلحات موضوعية: MESH: Crowding, MESH: Female, MESH: ras Proteins, MESH: rho GTP-Binding Proteins, MESH: Social Participation, MESH: rho-Associated Kinases, MESH: Hinduism, MESH: Humans, MESH: India, MESH: Longitudinal Studies, MESH: Male, MESH: Middle Aged, MESH: Neurofibromin 1, MESH: Questionnaires, MESH: Actin Depolymerizing Factors, MESH: Actins, MESH: Enzyme Activation, MESH: HEK293 Cells, MESH: HeLa Cells, MESH: Lim Kinases, MESH: Models, Biological, MESH: Phosphorylation, MESH: Health, MESH: Protein Binding, MESH: Protein Structure, Tertiary, MESH: Signal Transduction, MESH: Stress Fibers, MESH: Two-Hybrid System Techniques
Relation: info:eu-repo/semantics/altIdentifier/pmid/23082153; hal-03054185; https://hal.science/hal-03054185; https://hal.science/hal-03054185/document; https://hal.science/hal-03054185/file/2012%20PLOS%20ONE%20LIMK2%20NF1.pdf; PUBMED: 23082153
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20Academic Journal
المؤلفون: Serra-Nédélec, Audrey de Rocca, Edouard, Thomas, Tréguera, Karine, Tajan, Mylène, Araki, Toshiyuki, Dance, Marie, Mus, Marianne, Montagner, Alexandra, Tauber, Maïté, Salles, Jean-Pierre, Valet, Philippe, Neel, Benjamin G., Raynal, Patrick, Yart, Armelle
المساهمون: Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mécanismes des cardiopathies et résistance hormonale dans le Noonan et syndrome apparentés (M2CHRNRS), Université de Toulouse (UT)-Université de Toulouse (UT), Centre d'Endocrinologie, Maladies Osseuses, Génétique et Gynécologie Médicale, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Campbell Family Cancer Research Institute, University of Toronto-Ontario Cancer Institute, Laboratoire de biologie moléculaire eucaryote (LBME), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre de Physiopathologie Toulouse Purpan (CPTP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), ToxAlim (ToxAlim), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Ontario Cancer Institute, Melanie H. Cobb
المصدر: ISSN: 0027-8424.
مصطلحات موضوعية: DELETION, PTPN11 SHP2, MOUSE MODEL, MUTATIONS, growth hormone insensitivity, signaling, TYROSINE-PHOSPHATASE SHP2, ACTIVATED PROTEIN-KINASE, SIGNALING PATHWAYS, HEIGHT, MALFORMATIONS, DEFECTS, MESH: Animals, Newborn, MESH: Mitogen-Activated Protein Kinase Kinases, MESH: STAT5 Transcription Factor, MESH: Binding Sites, MESH: ras Proteins, MESH: Biometry, MESH: Enzyme Activation, MESH: Extracellular Signal-Regulated MAP Kinases, MESH: Growth Hormone, MESH: Insulin-Like Growth Factor I, MESH: Janus Kinase 2, MESH: Mutation, MESH: Mice, MESH: Noonan Syndrome, MESH: Phosphatidylinositol 3-Kinases, MESH: Phosphoproteins, MESH: Phosphorylation
Relation: info:eu-repo/semantics/altIdentifier/pmid/22371576; PRODINRA: 387290; PUBMED: 22371576; WOS: 000301426700049