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1Academic Journal
المؤلفون: Sauguet, Ludovic
المساهمون: Dynamique structurale des Macromolécules / Structural Dynamics of Macromolecules, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), The work is funded by an ANR JCJC grant ANR-17-CE11-0005-01 and Institut Pasteur., The author wishes to thank Pierre Béguin, Pierre Raia, Clément Madru, and Marc Delarue for helpful discussions., ANR-17-CE11-0005,ARCHAPOL,Spécificités structurales et potentiel biotechnologique de la PolD, une ADN polymérase atypique d'archée(2017)
المصدر: ISSN: 0022-2836.
مصطلحات موضوعية: two-barrel minimal core, evolution, double-psi β-barrel, RNA polymerase, DNA polymerase, MESH: Catalytic Domain, MESH: DNA-Directed DNA Polymerase / chemistry, MESH: Protein Conformation, MESH: Protein Subunits / chemistry, MESH: Protein Subunits / genetics, MESH: Protein Subunits / metabolism, MESH: DNA-Directed DNA Polymerase / genetics, MESH: DNA-Directed DNA Polymerase / metabolism, MESH: DNA-Directed RNA Polymerases / chemistry, MESH: DNA-Directed RNA Polymerases / genetics, MESH: DNA-Directed RNA Polymerases / metabolism, MESH: Evolution, Molecular, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/31103775; pasteur-02888332; https://hal-pasteur.archives-ouvertes.fr/pasteur-02888332; https://hal-pasteur.archives-ouvertes.fr/pasteur-02888332/document; https://hal-pasteur.archives-ouvertes.fr/pasteur-02888332/file/S0022283619302864.pdf; PII: S0022-2836(19)30286-4; PUBMED: 31103775
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2Academic Journal
المؤلفون: Bailly, B., Richard, C.-A., Sharma, G., Wang, L., Johansen, L., Cao, J., Pendharkar, V., Sharma, D.-C., Galloux, Marie, Wang, Y., Cui, R., Zou, G., Guillon, P., von Itzstein, M., Eléouët, J.-F., Altmeyer, R.
المساهمون: Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Pasteur Network (Réseau International des Instituts Pasteur), Institute for Glycomics, Griffith University Brisbane, Shandong University, Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)), Institut National de la Recherche Agronomique (INRA), CombinatoRx, Qingdao Municipal Center for Disease Control and Prevention, Partenaires INRAE, Department of Biosystems (BIOSYST), Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), ANR-11-BSV8-0024,BRONCHIOLITEASER,Etude structurale et fonctionnelle du complexe polymérase du virus respiratoire syncytial et recherche d'inhibiteurs(2011)
المصدر: ISSN: 2045-2322.
مصطلحات موضوعية: MESH: Alkaloids / pharmacology, MESH: Animals, MESH: Models, Molecular, MESH: Respiratory Syncytial Virus Infections / drug therapy, MESH: Respiratory Syncytial Virus Infections / virology, MESH: Respiratory Syncytial Virus, Human / drug effects, Human / physiology, MESH: Smoothened Receptor / metabolism, MESH: Transcription, Genetic* / drug effects, MESH: Veratrum / chemistry, MESH: Veratrum Alkaloids / chemistry, MESH: Veratrum Alkaloids / pharmacology, MESH: Cell Line, MESH: Veratrum Alkaloids / therapeutic use, MESH: Viral Proteins / metabolism, MESH: Virus Replication / drug effects, MESH: Virus Replication / genetics, MESH: Virus Replication / physiology, MESH: DNA-Directed RNA Polymerases / metabolism, MESH: Disease Models, Animal, MESH: Drug Resistance, Viral / drug effects, MESH: Female, MESH: Gene Expression Regulation, MESH: Humans, MESH: Mice
Relation: info:eu-repo/semantics/altIdentifier/pmid/27194388; PUBMED: 27194388; PUBMEDCENTRAL: PMC4872165; WOS: 000376372700001
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3Academic Journal
المؤلفون: Cavaliere, Paola, Sizun, Christina, Levi-Acobas, Fabienne, Nowakowski, Mireille, Monteil, Véronique, Bontems, François, Bellalou, Jacques, Mayer, Claudine, Norel, Françoise
المساهمون: Systèmes macromoléculaires et Signalisation, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles (ICSN), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Production de Protéines Recombinantes (Plate-Forme) (PRPF), Université Paris Diderot - Paris 7 (UPD7), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur Paris (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), This work was supported by the French National Research Agency grant ANR- 11-BSV3-009 , the IR-RMN-THC (CNRS FR3050) for access to the 950 MHz spectrometer at Gif-sur-Yvette for preliminary experiments and by grants from the Institut Pasteur and the Centre National de la Recherche Scientifique. The WeNMR project (European FP7 e-Infrastructure grant, contract no. 261572, www.wenmr.eu), supported by the European Grid Initiative (EGI) through the national GRID Initiatives of Belgium, France, Italy, Germany, the Netherlands, Poland, Portugal, Spain, UK, South Africa, Malaysia, Taiwan, the Latin America GRID infrastructure via the Gisela project and the US Open Science Grid (OSG) are acknowledged for the use of web portals, computing and storage facilities., ANR-11-BSV3-0009,SIGMADAPT,Rôle de SigmaS dans la compétitivité et l'adaptation des bactéries à l'environnement(2011), European Project: 261572,EC:FP7:INFRA,FP7-INFRASTRUCTURES-2010-2,WENMR(2010)
المصدر: ISSN: 2045-2322.
مصطلحات موضوعية: MESH: Amino Acid Sequence, MESH: Amino Acid Substitution, MESH: Molecular Docking Simulation, MESH: Molecular Sequence Data, MESH: Protein Binding, MESH: Protein Conformation, MESH: Protein Subunits, MESH: Pseudomonas aeruginosa/metabolism, MESH: Salmonella/metabolism, MESH: Sigma Factor/chemistry, MESH: Sigma Factor/metabolism, MESH: Sigma Factor/ultrastructure, MESH: Bacterial Proteins/chemistry, MESH: Species Specificity, MESH: Structure-Activity Relationship, MESH: Bacterial Proteins/metabolism, MESH: Bacterial Proteins/ultrastructure, MESH: Binding Sites, MESH: DNA-Directed RNA Polymerases/chemistry, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: DNA-Directed RNA Polymerases/ultrastructure, MESH: Models, Chemical, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/26338235; info:eu-repo/grantAgreement/EC/FP7/261572/EU/A worldwide e-Infrastructure for NMR and structural biology/WENMR; pasteur-01392714; https://pasteur.hal.science/pasteur-01392714; https://pasteur.hal.science/pasteur-01392714/document; https://pasteur.hal.science/pasteur-01392714/file/srep13564.pdf; PUBMED: 26338235
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4Academic Journal
المؤلفون: Baharoglu, Z., Babosan, A., Mazel, D.
المساهمون: Plasticité du Génome Bactérien - Bacterial Genome Plasticity (PGB), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur, the Centre National de la Recherche Scientifique CNRS-UMR3525, the European Union Seventh Framework Programme FP7-HEALTH-2011- single-stage ‘Evolution and Transfer of Antibiotic Resistance’ (EvoTAR), and the French Government’s Investissement d’Avenir program Laboratoire d’Excellence ‘Integrative Biology of Emerging Infectious Diseases’ ANR-10-LABX-62-IBEID . Z.B. is supported by a DIM Malinf postdoctoral fellowship (Conseil régional d’Ile-de-France) and EvoTAR., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 282004,EC:FP7:HEALTH,FP7-HEALTH-2011-single-stage,EVOTAR(2011)
المصدر: ISSN: 0305-1048.
مصطلحات موضوعية: MESH: Anti-Bacterial Agents/pharmacology, MESH: Bacterial Proteins/genetics, MESH: Transcription Factors/metabolism, MESH: Transcription Factors/physiology, MESH: Bacterial Proteins/metabolism, MESH: Transcription, Genetic, MESH: Ultraviolet Rays, MESH: Vibrio cholerae/drug effects, MESH: Vibrio cholerae/enzymology, MESH: Vibrio cholerae/genetics, MESH: Bacterial Proteins/physiology, MESH: DNA Damage, MESH: Gene Deletion, MESH: DNA Helicases/genetics, MESH: DNA Helicases/metabolism, MESH: DNA Helicases/physiology, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Escherichia coli/radiation effects, MESH: Genes, Bacterial, MESH: MutS DNA Mismatch-Binding Protein/genetics, MESH: Mutation, MESH: Ribonuclease H/metabolism, MESH: SOS Response (Genetics), MESH: Tobramycin/pharmacology, MESH: Transcription Factors/genetics, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Relation: info:eu-repo/semantics/altIdentifier/pmid/24319148; info:eu-repo/grantAgreement/EC/FP7/282004/EU/Evolution and Transfer of Antibiotic Resistance/EVOTAR; pasteur-01423602; https://hal-pasteur.archives-ouvertes.fr/pasteur-01423602; https://hal-pasteur.archives-ouvertes.fr/pasteur-01423602/document; https://hal-pasteur.archives-ouvertes.fr/pasteur-01423602/file/gkt1259.pdf; PUBMED: 24319148
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5Diversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes
المؤلفون: Julien Guglielmini, Morgan Gaia, Patrick Forterre, Anthony C. Woo, Mart Krupovic
المساهمون: Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie Moléculaire du Gène chez les Extrêmophiles (BMGE), Institut Pasteur [Paris] (IP), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Biologie Cellulaire des Archées (ARCHEE), Département Microbiologie (Dpt Microbio), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), This work was supported by a European Research Council grant from the European Union’s Seventh Framework Program (FP/2007-2013)/Project EVOMOBIL-ERC Grant Agreement 340440., We thank Alexis Criscuolo for his expert support in computational analyses and the development of the online platform, and Violette Da Cunha for assistance., European Project: 340440,EC:FP7:ERC,ERC-2013-ADG,EVOMOBIL(2014), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (39), pp.19585-19592. ⟨10.1073/pnas.1912006116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (39), pp.19585-19592. ⟨10.1073/pnas.1912006116⟩مصطلحات موضوعية: [SDV]Life Sciences [q-bio], MESH: DNA-Directed RNA Polymerases / genetics, Biology, MESH: Eukaryotic Cells / metabolism, proto-eukaryotes, MESH: Biological Evolution, 03 medical and health sciences, chemistry.chemical_compound, RNA polymerase, evolution, MESH: Eukaryota / genetics, Human virome, Giant Virus, MESH: DNA-Directed RNA Polymerases / metabolism, Clade, MESH: Phylogeny, Gene, giant viruses, Polymerase, MESH: Evolution, Molecular, 030304 developmental biology, 0303 health sciences, Mimivirus, MESH: Cytoplasm / virology, Multidisciplinary, Phylogenetic tree, 030306 microbiology, MESH: Giant Viruses / genetics, RNA, DNA virus, Biological Sciences, biology.organism_classification, chemistry, Evolutionary biology, biology.protein, MESH: Cell Nucleus / genetics, NCLDV, MESH: Giant Viruses / metabolism, MESH: DNA Viruses / genetics
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6
المؤلفون: Ludovic Sauguet
المساهمون: Dynamique structurale des Macromolécules / Structural Dynamics of Macromolecules, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), The work is funded by an ANR JCJC grant ANR-17-CE11-0005-01 and Institut Pasteur., The author wishes to thank Pierre Béguin, Pierre Raia, Clément Madru, and Marc Delarue for helpful discussions., ANR-17-CE11-0005,ARCHAPOL,Spécificités structurales et potentiel biotechnologique de la PolD, une ADN polymérase atypique d'archée(2017), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
المصدر: Journal of Molecular Biology
Journal of Molecular Biology, 2019, 431 (20), pp.4167-4183. ⟨10.1016/j.jmb.2019.05.017⟩
Journal of Molecular Biology, Elsevier, 2019, 431 (20), pp.4167-4183. ⟨10.1016/j.jmb.2019.05.017⟩مصطلحات موضوعية: Protein Conformation, DNA polymerase, MESH: Protein Subunits / chemistry, DNA-Directed DNA Polymerase, Computational biology, MESH: DNA-Directed DNA Polymerase / genetics, Evolution, Molecular, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, MESH: Protein Conformation, Structural Biology, Transcription (biology), Catalytic Domain, RNA polymerase, MESH: DNA-Directed RNA Polymerases / genetics, evolution, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, two-barrel minimal core, MESH: DNA-Directed DNA Polymerase / metabolism, MESH: DNA-Directed RNA Polymerases / metabolism, Molecular Biology, Gene, Polymerase, MESH: Evolution, Molecular, 030304 developmental biology, MESH: Protein Subunits / genetics, 0303 health sciences, biology, MESH: Protein Subunits / metabolism, MESH: DNA-Directed RNA Polymerases / chemistry, DNA replication, RNA, DNA-Directed RNA Polymerases, Protein Subunits, MESH: DNA-Directed DNA Polymerase / chemistry, chemistry, double-psi β-barrel, biology.protein, MESH: Catalytic Domain, 030217 neurology & neurosurgery, DNA
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7Academic JournalDiversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes
المساهمون: Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie Moléculaire du Gène chez les Extrêmophiles (BMGE), Institut Pasteur Paris (IP), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Biologie Cellulaire des Archées (ARCHEE), Département Microbiologie (Dpt Microbio), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), This work was supported by a European Research Council grant from the European Union’s Seventh Framework Program (FP/2007-2013)/Project EVOMOBIL-ERC Grant Agreement 340440., We thank Alexis Criscuolo for his expert support in computational analyses and the development of the online platform, and Violette Da Cunha for assistance., European Project: 340440,EC:FP7:ERC,ERC-2013-ADG,EVOMOBIL(2014)
المصدر: ISSN: 0027-8424.
مصطلحات موضوعية: evolution, giant viruses, RNA polymerase, NCLDV, proto-eukaryotes, MESH: Biological Evolution, MESH: Cell Nucleus / genetics, MESH: Giant Viruses / metabolism, MESH: Phylogeny, MESH: Cytoplasm / virology, MESH: DNA Viruses / genetics, MESH: DNA-Directed RNA Polymerases / genetics, MESH: DNA-Directed RNA Polymerases / metabolism, MESH: Eukaryota / genetics, MESH: Eukaryotic Cells / metabolism, MESH: Evolution, Molecular, MESH: Giant Viruses / genetics, [SDV]Life Sciences [q-bio]
Relation: info:eu-repo/semantics/altIdentifier/pmid/31506349; info:eu-repo/grantAgreement/EC/FP7/340440/EU/Co-evolution of viruses, plasmids and cells in Archaea: pattern and process/EVOMOBIL; PUBMED: 31506349; PUBMEDCENTRAL: PMC6765235
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المؤلفون: Christina Sizun, Jacques Bellalou, Claudine Mayer, Véronique Monteil, Mireille Nowakowski, Fabienne Levi-Acobas, Françoise Norel, François Bontems, Paola Cavaliere
المساهمون: Systèmes macromoléculaires et Signalisation, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles (ICSN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Production de Protéines Recombinantes (Plate-Forme) (PRPF), Université Paris Diderot - Paris 7 (UPD7), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), This work was supported by the French National Research Agency [grant ANR- 11-BSV3-009], the IR-RMN-THC (CNRS FR3050) for access to the 950 MHz spectrometer at Gif-sur-Yvette for preliminary experiments and by grants from the Institut Pasteur and the Centre National de la Recherche Scientifique. The WeNMR project (European FP7 e-Infrastructure grant, contract no. 261572, www.wenmr.eu), supported by the European Grid Initiative (EGI) through the national GRID Initiatives of Belgium, France, Italy, Germany, the Netherlands, Poland, Portugal, Spain, UK, South Africa, Malaysia, Taiwan, the Latin America GRID infrastructure via the Gisela project and the US Open Science Grid (OSG) are acknowledged for the use of web portals, computing and storage facilities., ANR-11-BSV3-0009,SIGMADAPT,Rôle de SigmaS dans la compétitivité et l'adaptation des bactéries à l'environnement(2011), European Project: 261572,EC:FP7:INFRA,FP7-INFRASTRUCTURES-2010-2,WENMR(2010), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), Institut de Chimie des Substances Naturelles ( ICSN ), Centre National de la Recherche Scientifique ( CNRS ), Production de Protéines Recombinantes (Plate-Forme) ( PRPF ), Université Paris Diderot - Paris 7 ( UPD7 ), Microbiologie structurale, ANR-11-BSV3-0009,SIGMADAPT,Rôle de SigmaS dans la compétitivité et l'adaptation des bactéries à l'environnement ( 2011 ), European Project : 261572,EC:FP7:INFRA,FP7-INFRASTRUCTURES-2010-2,WENMR ( 2010 ), Institut Pasteur [Paris] - Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS), ANR-11-BSV3-0009, SIGMADAPT, Rôle de SigmaS dans la compétitivité et l'adaptation des bactéries à l'environnement(2011), European Project : 261572, EC:FP7:INFRA, FP7-INFRASTRUCTURES-2010-2, WENMR(2010)
المصدر: Scientific Reports
Scientific Reports, 2015, 5, pp.13564. ⟨10.1038/srep13564⟩
Scientific Reports, Nature Publishing Group, 2015, 5, pp.13564. ⟨10.1038/srep13564⟩
Scientific Reports, Nature Publishing Group, 2015, 5, pp.13564. 〈10.1038/srep13564〉
HAL-Pasteur
Hyper Article en Ligne
OpenAIRE
INRIA a CCSD electronic archive server
Europe PubMed Central
Hal-Diderotمصطلحات موضوعية: MESH : Models, Chemical, MESH: Pseudomonas aeruginosa/metabolism, MESH : Molecular Sequence Data, Protein Conformation, MESH : Protein Subunits, Plasma protein binding, MESH: Amino Acid Sequence, MESH: DNA-Directed RNA Polymerases/chemistry, chemistry.chemical_compound, Protein structure, MESH: Protein Conformation, MESH: Structure-Activity Relationship, MESH : Sigma Factor/ultrastructure, MESH: Bacterial Proteins/ultrastructure, Salmonella, Sigma factor, [ SDV.MP ] Life Sciences [q-bio]/Microbiology and Parasitology, RNA polymerase, MESH: Sigma Factor/metabolism, MESH: DNA-Directed RNA Polymerases/metabolism, MESH : Structure-Activity Relationship, MESH : Protein Conformation, Genetics, Multidisciplinary, MESH : Amino Acid Sequence, MESH: Models, Chemical, food and beverages, MESH : Protein Binding, DNA-Directed RNA Polymerases, MESH: Protein Subunits, MESH : Bacterial Proteins/ultrastructure, MESH: Amino Acid Substitution, Molecular Docking Simulation, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Biochemistry, Pseudomonas aeruginosa, MESH : Molecular Docking Simulation, MESH: Bacterial Proteins/metabolism, Protein Binding, MESH: Bacterial Proteins/chemistry, MESH : Salmonella/metabolism, MESH : Pseudomonas aeruginosa/metabolism, MESH : Sigma Factor/chemistry, Protein subunit, Molecular Sequence Data, MESH : DNA-Directed RNA Polymerases/chemistry, Sigma Factor, Biology, Article, Structure-Activity Relationship, MESH: DNA-Directed RNA Polymerases/ultrastructure, MESH : DNA-Directed RNA Polymerases/ultrastructure, MESH : Amino Acid Substitution, Bacterial Proteins, Species Specificity, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Molecular Docking Simulation, MESH: Sigma Factor/chemistry, MESH : Species Specificity, MESH : Bacterial Proteins/chemistry, MESH: Protein Binding, MESH: Species Specificity, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, MESH : DNA-Directed RNA Polymerases/metabolism, Binding site, Gene, [ SDV.BBM ] Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, Binding Sites, MESH: Molecular Sequence Data, fungi, MESH : Sigma Factor/metabolism, Protein Subunits, Amino Acid Substitution, Models, Chemical, chemistry, MESH: Binding Sites, MESH : Bacterial Proteins/metabolism, MESH: Salmonella/metabolism, rpoS, MESH : Binding Sites, MESH: Sigma Factor/ultrastructure
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المؤلفون: Abraham L. Sonenshein, Nagraj Mani, Bruno Dupuy
المساهمون: Department of Molecular Biology and Microbiology [Tufts, Boston], Tufts University School of Medicine [Boston], Génétique Moléculaire Bactérienne, Institut Pasteur [Paris] (IP), This work was supported by research grants to A.L.S. (grants AI057637 and GM042219) and a project grant to the Tufts Gastroenterology Research and Secretory Processes Center (grant DK034928) from the U.S. Public Health Service, by a postdoctoral fellowship to N.M. from the Charles A. King Trust, and by research funds provided to B.D. by the Institut Pasteur, Paris, France., We thank L. Barosso and T. Wilkins for providing the cloned gdh promoter region, the Sanger Centre for making the C. difficile genome sequence available prior to publication, and B. Belitsky, K. Matsuno, and J. Singh for helpful discussions., Institut Pasteur [Paris]
المصدر: Journal of Bacteriology
Journal of Bacteriology, 2005, 188 (1), pp.96-102. ⟨10.1128/JB.188.1.96-102.2006⟩
Journal of Bacteriology, American Society for Microbiology, 2005, 188 (1), pp.96-102. ⟨10.1128/JB.188.1.96-102.2006⟩مصطلحات موضوعية: Transcription, Genetic, MESH: Clostridium difficile/genetics, [SDV]Life Sciences [q-bio], Molecular Sequence Data, MESH: Base Sequence, Biology, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Glutamate Dehydrogenase, MESH: Genes, rRNA, Transcription (biology), MESH: DNA-Directed RNA Polymerases/metabolism, RNA polymerase, Gene expression, Transcriptional regulation, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Clostridium difficile/enzymology, Promoter Regions, Genetic, Molecular Biology, Gene, MESH: Transcription, Genetic, 030304 developmental biology, Molecular Biology of Pathogens, Regulation of gene expression, MESH: Gene Expression Regulation, Bacterial, 0303 health sciences, MESH: Humans, MESH: Molecular Sequence Data, Base Sequence, Clostridioides difficile, 030306 microbiology, MESH: Glutamate Dehydrogenase/metabolism, Genes, rRNA, Promoter, DNA-Directed RNA Polymerases, Gene Expression Regulation, Bacterial, Clostridium difficile, Molecular biology, MESH: DNA-Directed RNA Polymerases/isolation & purification, MESH: Glutamate Dehydrogenase/genetics, 3. Good health, chemistry, MESH: DNA-Directed RNA Polymerases/genetics, MESH: Promoter Regions, Genetic*/physiology
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10
المؤلفون: Lisa Barroso, Pauline Howarth, Julian I. Rood, Tracy D. Wilkins, Nagraj Mani, Dena Lyras, Bruno Dupuy, Abraham L. Sonenshein
المساهمون: Department of Molecular Biology and Microbiology [Tufts, Boston], Tufts University School of Medicine [Boston], Department of Microbiology [Monash University, Australia], School of Biomedical Sciences [Monash University, Clayton], Monash University [Clayton]-Monash University [Clayton], Fralin Biotechnology Center [Blacksburg], Virginia Tech [Blacksburg], Génétique Moléculaire Bactérienne, Institut Pasteur [Paris], This work was supported by a postdoctoral fellowship to N. Mani from the Charles A. King Trust, a research grant from the Public Health Service (GM42219) to A. L. Sonenshein, a grant from the Australian National Health and Medical Research Council to J. I. Rood, and funds from the Institut Pasteur (Paris)., We thank S. Cole for critical review of the manuscript, A. Kolb for the gift of E. coli σ70, D. Acheson for help in preparing antibody to TxeR, S. B. Melville for providing strain SM101, and S. Karlsson and colleagues for allowing us to cite their unpublished results., Institut Pasteur [Paris] (IP)
المصدر: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2002, 184 (21), pp.5971-5978. ⟨10.1128/jb.184.21.5971-5978.2002⟩
Monash University
Journal of Bacteriology, 2002, 184 (21), pp.5971-5978. ⟨10.1128/jb.184.21.5971-5978.2002⟩مصطلحات موضوعية: Transcriptional Activation, MESH: Transcriptional Activation, Clostridium perfringens, [SDV]Life Sciences [q-bio], Sigma Factor, Environment, Biology, Microbiology, MESH: Clostridium perfringens/genetics, 03 medical and health sciences, Plasmid, Bacterial Proteins, Sigma factor, Transcription (biology), MESH: Sigma Factor/metabolism, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Promoter Regions, Genetic, Gene expression, Escherichia coli, Homeostasis, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Promoter Regions, Genetic, MESH: Environment, Molecular Biology, Gene, MESH: Clostridium perfringens/growth & development, 030304 developmental biology, Molecular Biology of Pathogens, Regulation of gene expression, 0303 health sciences, Reporter gene, Clostridioides difficile, MESH: Escherichia coli, 030306 microbiology, MESH: Sigma Factor/genetics, Promoter, DNA-Directed RNA Polymerases, Gene Expression Regulation, Bacterial, Molecular biology, MESH: Homeostasis, MESH: Clostridium difficile/genetics, MESH: Bacterial Proteins/genetics, MESH: Bacterial Proteins/metabolism, MESH: Gene Expression Regulation, Bacterial
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11
المؤلفون: Zeynep Baharoglu, Didier Mazel, Anamaria Babosan
المساهمون: Plasticité du Génome Bactérien - Bacterial Genome Plasticity (PGB), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur, the Centre National de la Recherche Scientifique [CNRS-UMR3525], the European Union Seventh Framework Programme [FP7-HEALTH-2011- single-stage] ‘Evolution and Transfer of Antibiotic Resistance’ (EvoTAR), and the French Government’s Investissement d’Avenir program Laboratoire d’Excellence ‘Integrative Biology of Emerging Infectious Diseases’ [ANR-10-LABX-62-IBEID]. Z.B. is supported by a DIM Malinf postdoctoral fellowship (Conseil régional d’Ile-de-France) and EvoTAR., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 282004,EC:FP7:HEALTH,FP7-HEALTH-2011-single-stage,EVOTAR(2011), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
المصدر: Nucleic Acids Research
Nucleic Acids Research, 2014, 42 (4), pp.2366-2379. ⟨10.1093/nar/gkt1259⟩
Nucleic Acids Research, Oxford University Press, 2014, 42 (4), pp.2366-2379. ⟨10.1093/nar/gkt1259⟩مصطلحات موضوعية: Transcription, Genetic, MESH: SOS Response (Genetics), MESH: DNA Helicases/metabolism, Genome Integrity, Repair and Replication, medicine.disease_cause, chemistry.chemical_compound, MESH: MutS DNA Mismatch-Binding Protein/genetics, Transcription (biology), MESH: Anti-Bacterial Agents/pharmacology, RNA polymerase, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Tobramycin/pharmacology, SOS response, Vibrio cholerae, MESH: Transcription Factors/metabolism, MESH: Transcription, Genetic, MESH: Ribonuclease H/metabolism, biology, MESH: Vibrio cholerae/genetics, DNA-Directed RNA Polymerases, MESH: Escherichia coli/radiation effects, MutS DNA Mismatch-Binding Protein, Anti-Bacterial Agents, MESH: Vibrio cholerae/drug effects, Tobramycin, MESH: Genes, Bacterial, MESH: Bacterial Proteins/metabolism, MESH: Mutation, Ultraviolet Rays, Ribonuclease H, MESH: DNA Helicases/genetics, MESH: Bacterial Proteins/genetics, MESH: Vibrio cholerae/enzymology, MESH: Bacterial Proteins/physiology, SOS Response (Genetics), Bacterial Proteins, Escherichia coli, Genetics, medicine, SOS Response, Genetics, MESH: Transcription Factors/genetics, Gene, MESH: DNA Damage, [SDV.GEN]Life Sciences [q-bio]/Genetics, DNA Helicases, Helicase, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Molecular biology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, chemistry, Genes, Bacterial, MESH: Gene Deletion, Mutation, biology.protein, bacteria, MESH: Transcription Factors/physiology, MESH: Ultraviolet Rays, MESH: DNA Helicases/physiology, Gene Deletion, DNA, DNA Damage, Transcription Factors
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12Academic Journal
المؤلفون: Dupuy, Bruno, Raffestin, Stephanie, Matamouros, Susana, Mani, Nagraj, Popoff, Michel, Sonenshein, Abraham
المساهمون: Génétique Moléculaire Bactérienne, Institut Pasteur Paris (IP), Bactéries anaérobies et Toxines, Tufts University School of Medicine Boston, This work was supported by funds from the Institut Pasteur (to B.D. and M.R.P.), by research grants (GM042219 and AI057637) from the US Public Health Service (to A.L.S.), by a postdoctoral fellowship from the Charles A. King Trust (to N.M.), by a DGA contract (0034054) and a DGA fellowship awarded to S.R. and by a predoctoral fellowship from the Fundação para a Ciência e a Tecnologia (SFRH/BD/6064/2001) (Portugal) (to S.M.)., We thank S.T. Cole for supporting this project, Ana Sofia Antunes for her valuable help in Bacillus strains construction and S.S. Dineen for helpful advice and critical comments on the manuscript.
المصدر: ISSN: 0950-382X.
مصطلحات موضوعية: MESH: Amino Acid Sequence, MESH: Bacillus subtilis/genetics, MESH: Genes, Bacterial, MESH: Genetic Complementation Test, MESH: Molecular Sequence Data, MESH: Sigma Factor/genetics, MESH: Sigma Factor/metabolism, MESH: Transcription, Genetic, MESH: Bacterial Toxins/genetics, MESH: Bacteriocins/genetics, MESH: Clostridium/enzymology, MESH: Clostridium/genetics, MESH: DNA-Directed RNA Polymerases/genetics, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Gene Expression Regulation, MESH: Gene Order, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/16677313; pasteur-02444078; https://hal-pasteur.archives-ouvertes.fr/pasteur-02444078; PUBMED: 16677313
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13Academic Journal
المساهمون: Bactéries anaérobies et Toxines, Institut Pasteur Paris (IP), Génétique Moléculaire Bactérienne, This work was supported by a DRET Contract (0034056), a GPH 9 Institut Pasteur and a DGA Fellowship awarded to SR. We thank C. Dane for supporting this project., We thank A. Kolb for helpful discussion and B. Stiles for reading the manuscript.
المصدر: ISSN: 0950-382X.
مصطلحات موضوعية: MESH: Bacterial Proteins/genetics, MESH: Bacterial Proteins/physiology, MESH: DNA-Binding Proteins/metabolism, MESH: DNA-Directed RNA Polymerases/genetics, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: DNA-Directed RNA Polymerases/physiology, MESH: Gene Expression Regulation, Bacterial, MESH: Molecular Sequence Data, MESH: Promoter Regions, Genetic, MESH: Protein Binding, MESH: Sigma Factor/genetics, MESH: Sigma Factor/physiology, MESH: Base Sequence, MESH: Tetanus Toxin/genetics, MESH: Trans-Activators/genetics, MESH: Trans-Activators/physiology, MESH: Botulinum Toxins/genetics, MESH: Clostridium botulinum/genetics, MESH: Clostridium botulinum/physiology, MESH: Clostridium tetani/genetics, MESH: Clostridium tetani/physiology, MESH: DNA, MESH: DNA-Binding Proteins/genetics, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/15612931; pasteur-02444103; https://pasteur.hal.science/pasteur-02444103; PUBMED: 15612931
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14Academic Journal
المؤلفون: Mani, N., Dupuy, B., Sonenshein, A.
المساهمون: Department of Molecular Biology and Microbiology Tufts, Boston, Tufts University School of Medicine Boston, Génétique Moléculaire Bactérienne, Institut Pasteur Paris (IP), This work was supported by research grants to A.L.S. (grants AI057637 and GM042219) and a project grant to the Tufts Gastroenterology Research and Secretory Processes Center (grant DK034928) from the U.S. Public Health Service, by a postdoctoral fellowship to N.M. from the Charles A. King Trust, and by research funds provided to B.D. by the Institut Pasteur, Paris, France., We thank L. Barosso and T. Wilkins for providing the cloned gdh promoter region, the Sanger Centre for making the C. difficile genome sequence available prior to publication, and B. Belitsky, K. Matsuno, and J. Singh for helpful discussions.
المصدر: ISSN: 0021-9193.
مصطلحات موضوعية: MESH: Base Sequence, MESH: Clostridium difficile/enzymology, MESH: Humans, MESH: Molecular Sequence Data, MESH: Promoter Regions, Genetic*/physiology, MESH: Transcription, Genetic, MESH: Clostridium difficile/genetics, MESH: DNA-Directed RNA Polymerases/genetics, MESH: DNA-Directed RNA Polymerases/isolation & purification, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Gene Expression Regulation, Bacterial, MESH: Genes, rRNA, MESH: Glutamate Dehydrogenase/genetics, MESH: Glutamate Dehydrogenase/metabolism, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/16352825; pasteur-02444092; https://hal-pasteur.archives-ouvertes.fr/pasteur-02444092; PUBMED: 16352825; PUBMEDCENTRAL: PMC1317598
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15Academic Journal
المؤلفون: Cheung, J., Dupuy, B., Deveson, D., Rood, J.
المساهمون: Department of Microbiology Monash University, Australia, School of Biomedical Sciences Monash University, Clayton, Monash University Clayton -Monash University Clayton, Génétique Moléculaire Bactérienne, Institut Pasteur Paris (IP), This research was supported by grants from the Australian National Health and Medical Research Council., We thank Sheena McGowan for helpful discussions and Sei-ichi Katayama for kindly providing C. perfringens RNA polymerase.
المصدر: ISSN: 0021-9193.
مصطلحات موضوعية: MESH: Bacterial Proteins/chemistry, MESH: Bacterial Proteins/physiology, MESH: Nucleic Acid Conformation, MESH: Promoter Regions, Genetic, MESH: Transcriptional Activation, MESH: Bacterial Toxins/genetics, MESH: Base Sequence, MESH: Clostridium perfringens/genetics, MESH: DNA, Bacterial/chemistry, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Gene Expression Regulation, Bacterial, MESH: Hemolysin Proteins, MESH: Molecular Sequence Data, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/15150217; pasteur-02445942; https://hal-pasteur.archives-ouvertes.fr/pasteur-02445942; PUBMED: 15150217; PUBMEDCENTRAL: PMC415773
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16
المؤلفون: Stéphanie Raffestin, Abraham L. Sonenshein, Michel R. Popoff, Susana Matamouros, Bruno Dupuy, Nagraj Mani
المساهمون: Génétique Moléculaire Bactérienne, Institut Pasteur [Paris], Bactéries anaérobies et Toxines, Tufts University School of Medicine [Boston], This work was supported by funds from the Institut Pasteur (to B.D. and M.R.P.), by research grants (GM042219 and AI057637) from the US Public Health Service (to A.L.S.), by a postdoctoral fellowship from the Charles A. King Trust (to N.M.), by a DGA contract (0034054) and a DGA fellowship awarded to S.R. and by a predoctoral fellowship from the Fundação para a Ciência e a Tecnologia (SFRH/BD/6064/2001) (Portugal) (to S.M.)., We thank S.T. Cole for supporting this project, Ana Sofia Antunes for her valuable help in Bacillus strains construction and S.S. Dineen for helpful advice and critical comments on the manuscript., Institut Pasteur [Paris] (IP)
المصدر: Molecular Microbiology
Molecular Microbiology, Wiley, 2006, 60 (4), pp.1044-1057. ⟨10.1111/j.1365-2958.2006.05159.x⟩
Molecular Microbiology, 2006, 60 (4), pp.1044-1057. ⟨10.1111/j.1365-2958.2006.05159.x⟩مصطلحات موضوعية: Transcription, Genetic, [SDV]Life Sciences [q-bio], MESH: Amino Acid Sequence, MESH: Sigma Factor/genetics, medicine.disease_cause, MESH: Gene Order, chemistry.chemical_compound, Clostridium, Bacteriocins, Sigma factor, Transcription (biology), RNA polymerase, Gene Order, Genetics, 0303 health sciences, MESH: Genetic Complementation Test, biology, MESH: Bacteriocins/genetics, MESH: Bacillus subtilis/genetics, DNA-Directed RNA Polymerases, MESH: Clostridium/genetics, MESH: DNA-Directed RNA Polymerases/genetics, MESH: Genes, Bacterial, Bacillus subtilis, MESH: Gene Expression Regulation, Bacterial, MESH: DNA-Directed RNA Polymerases/metabolism, Bacterial Toxins, Molecular Sequence Data, Sigma Factor, Microbiology, 03 medical and health sciences, medicine, TetR, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, Molecular Biology, Gene, 030304 developmental biology, MESH: Molecular Sequence Data, 030306 microbiology, MESH: Transcription, Genetic, Genetic Complementation Test, Promoter, Gene Expression Regulation, Bacterial, Clostridium perfringens, biology.organism_classification, chemistry, Genes, Bacterial, MESH: Sigma Factor/metabolism, MESH: Clostridium/enzymology, MESH: Bacterial Toxins/genetics
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17
المساهمون: Bactéries anaérobies et Toxines, Institut Pasteur [Paris], Génétique Moléculaire Bactérienne, This work was supported by a DRET Contract (0034056), a GPH 9 Institut Pasteur and a DGA Fellowship awarded to SR. We thank C. Dane for supporting this project., We thank A. Kolb for helpful discussion and B. Stiles for reading the manuscript., Institut Pasteur [Paris] (IP)
المصدر: Molecular Microbiology
Molecular Microbiology, Wiley, 2005, 55 (1), pp.235-249. ⟨10.1111/j.1365-2958.2004.04377.x⟩
Molecular Microbiology, 2005, 55 (1), pp.235-249. ⟨10.1111/j.1365-2958.2004.04377.x⟩مصطلحات موضوعية: Botulinum Toxins, Clostridium tetani, Operon, [SDV]Life Sciences [q-bio], MESH: Sigma Factor/genetics, MESH: Base Sequence, medicine.disease_cause, chemistry.chemical_compound, Clostridium, Sigma factor, MESH: DNA-Directed RNA Polymerases/metabolism, Clostridium botulinum, Botulism, Promoter Regions, Genetic, MESH: DNA-Directed RNA Polymerases/physiology, MESH: Clostridium botulinum/physiology, 0303 health sciences, biology, MESH: Sigma Factor/physiology, DNA-Directed RNA Polymerases, 3. Good health, DNA-Binding Proteins, MESH: DNA-Directed RNA Polymerases/genetics, MESH: Botulinum Toxins/genetics, Protein Binding, MESH: Gene Expression Regulation, Bacterial, DNA, Bacterial, MESH: Tetanus Toxin/genetics, Clostridium botulinum type A, Molecular Sequence Data, Sigma Factor, MESH: Bacterial Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, Microbiology, MESH: Bacterial Proteins/physiology, MESH: Clostridium tetani/physiology, MESH: Trans-Activators/physiology, 03 medical and health sciences, Bacterial Proteins, Tetanus Toxin, MESH: Promoter Regions, Genetic, medicine, MESH: Protein Binding, TetR, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Molecular Biology, MESH: Clostridium tetani/genetics, 030304 developmental biology, MESH: DNA-Binding Proteins/genetics, MESH: Molecular Sequence Data, Base Sequence, MESH: Trans-Activators/genetics, 030306 microbiology, MESH: Clostridium botulinum/genetics, Gene Expression Regulation, Bacterial, biochemical phenomena, metabolism, and nutrition, medicine.disease, biology.organism_classification, Molecular biology, MESH: DNA, Bacterial, chemistry, Trans-Activators
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18
المؤلفون: Julian I. Rood, Jackie K. Cheung, Bruno Dupuy, Deanna S. Deveson
المساهمون: Department of Microbiology [Monash University, Australia], School of Biomedical Sciences [Monash University, Clayton], Monash University [Clayton]-Monash University [Clayton], Génétique Moléculaire Bactérienne, Institut Pasteur [Paris], This research was supported by grants from the Australian National Health and Medical Research Council., We thank Sheena McGowan for helpful discussions and Sei-ichi Katayama for kindly providing C. perfringens RNA polymerase., Institut Pasteur [Paris] (IP)
المصدر: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2004, 186 (11), pp.3321-3330. ⟨10.1128/JB.186.11.3321-3330.2004⟩
Journal of Bacteriology, 2004, 186 (11), pp.3321-3330. ⟨10.1128/JB.186.11.3321-3330.2004⟩مصطلحات موضوعية: DNA, Bacterial, Transcriptional Activation, Clostridium perfringens, [SDV]Life Sciences [q-bio], Mutant, Bacterial Toxins, Molecular Sequence Data, Biology, MESH: Base Sequence, medicine.disease_cause, Microbiology, MESH: Bacterial Proteins/physiology, 03 medical and health sciences, chemistry.chemical_compound, Hemolysin Proteins, MESH: DNA, Bacterial/chemistry, Bacterial Proteins, RNA polymerase, MESH: DNA-Directed RNA Polymerases/metabolism, Gene expression, MESH: Promoter Regions, Genetic, Transcriptional regulation, medicine, Direct repeat, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Gene Regulation, Promoter Regions, Genetic, Molecular Biology, Gene, 030304 developmental biology, Genetics, 0303 health sciences, MESH: Molecular Sequence Data, Base Sequence, 030306 microbiology, DNA-Directed RNA Polymerases, Gene Expression Regulation, Bacterial, MESH: Clostridium perfringens/genetics, Response regulator, MESH: Nucleic Acid Conformation, chemistry, MESH: Hemolysin Proteins, MESH: Transcriptional Activation, Nucleic Acid Conformation, MESH: Bacterial Proteins/chemistry, MESH: Bacterial Toxins/genetics, MESH: Gene Expression Regulation, Bacterial
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19Academic JournalRegulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor
المساهمون: Department of Molecular Biology and Microbiology Tufts, Boston, Tufts University School of Medicine Boston, Génétique Moléculaire Bactérienne, Institut Pasteur Paris (IP), This work was supported by funds from the Institut Pasteur and by a research grant (GM42219) from the U.S. Public Health Service to A. L. Sonenshein. N.M. was a fellow of the Charles A. King Trust. Preliminary studies were aided by pilot project funds from a U.S. Public Health Service grant (DK34928) to the Gastroenterology Research and Secretory Proteins Center., We thank A. L. Sonenshein for advice, encouragement, and assistance with the manuscript, T. Msadek and A. Chastonet for their valuable help in protein purification, A. Kolb and G. Orsini for helpful advice on gel-retardation experiments, J. Helmann for the gift of B. subtilis core enzyme, L. Barroso and T. Wilkins for making the gdh gene sequence available before publication, and G. Reysset, S. T. Cole, A. Wright, and B. Belitsky for critical reading of the manuscript.
المصدر: ISSN: 0027-8424.
مصطلحات موضوعية: MESH: Bacterial Toxins/biosynthesis, MESH: Bacterial Toxins/genetics, MESH: Clostridium difficile/genetics, MESH: Clostridium difficile/metabolism, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: Escherichia coli/enzymology, MESH: Gene Expression Regulation, Bacterial/physiology, MESH: Promoter Regions, Genetic, MESH: Protein Binding, MESH: Sigma Factor/physiology, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/11320220; pasteur-02445958; https://hal-pasteur.archives-ouvertes.fr/pasteur-02445958; PUBMED: 11320220; PUBMEDCENTRAL: PMC33301
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20Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor
المؤلفون: Bruno Dupuy, Nagraj Mani
المساهمون: Department of Molecular Biology and Microbiology [Tufts, Boston], Tufts University School of Medicine [Boston], Génétique Moléculaire Bactérienne, Institut Pasteur [Paris], This work was supported by funds from the Institut Pasteur and by a research grant (GM42219) from the U.S. Public Health Service to A. L. Sonenshein. N.M. was a fellow of the Charles A. King Trust. Preliminary studies were aided by pilot project funds from a U.S. Public Health Service grant (DK34928) to the Gastroenterology Research and Secretory Proteins Center., We thank A. L. Sonenshein for advice, encouragement, and assistance with the manuscript, T. Msadek and A. Chastonet for their valuable help in protein purification, A. Kolb and G. Orsini for helpful advice on gel-retardation experiments, J. Helmann for the gift of B. subtilis core enzyme, L. Barroso and T. Wilkins for making the gdh gene sequence available before publication, and G. Reysset, S. T. Cole, A. Wright, and B. Belitsky for critical reading of the manuscript., Institut Pasteur [Paris] (IP)
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2001, 98 (10), pp.5844-5849. ⟨10.1073/pnas.101126598⟩
Proceedings of the National Academy of Sciences of the United States of America, 2001, 98 (10), pp.5844-5849. ⟨10.1073/pnas.101126598⟩مصطلحات موضوعية: MESH: Bacterial Toxins/genetics, MESH: Clostridium difficile/genetics, MESH: Clostridium difficile/metabolism, MESH: Escherichia coli/enzymology, [SDV]Life Sciences [q-bio], Bacterial Toxins, Clostridium difficile toxin A, Sigma Factor, Biology, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Sigma factor, Transcription (biology), RNA polymerase, MESH: DNA-Directed RNA Polymerases/metabolism, Gene expression, Gene cluster, MESH: Promoter Regions, Genetic, Escherichia coli, MESH: Protein Binding, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Promoter Regions, Genetic, MESH: Gene Expression Regulation, Bacterial/physiology, 030304 developmental biology, 0303 health sciences, Multidisciplinary, 030306 microbiology, Clostridioides difficile, MESH: Bacterial Toxins/biosynthesis, MESH: Sigma Factor/physiology, Pseudomembranous colitis, DNA-Directed RNA Polymerases, Gene Expression Regulation, Bacterial, Clostridium difficile, Biological Sciences, Molecular biology, 3. Good health, chemistry, bacteria, Protein Binding