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1Academic Journal
المؤلفون: Grange, Laura, J, Reynolds, John, J, Ullah, Farid, Isidor, Bertrand, Shearer, Robert, F, Latypova, Xenia, Baxley, Ryan, M, Oliver, Antony, W, Ganesh, Anil, Cooke, Sophie, L, Jhujh, Satpal, S, Mcnee, Gavin, S, Hollingworth, Robert, Higgs, Martin, R, Natsume, Toyoaki, Khan, Tahir, Martos-Moreno, Gabriel, Á, Chupp, Sharon, Mathew, Christopher, G, Parry, David, Simpson, Michael, A, Nahavandi, Nahid, Yüksel, Zafer, Drasdo, Mojgan, Kron, Anja, Vogt, Petra, Jonasson, Annemarie, Seth, Saad, Ahmed, Gonzaga-Jauregui, Claudia, Brigatti, Karlla, W, Stegmann, Alexander, P A, Kanemaki, Masato, Josifova, Dragana, Uchiyama, Yuri, Oh, Yukiko, Morimoto, Akira, Osaka, Hitoshi, Ammous, Zineb, Argente, Jesús, Matsumoto, Naomichi, Stumpel, Constance, T R M, Taylor, Alexander, M R, Jackson, Andrew, P, Bielinsky, Anja-Katrin, Mailand, Niels, Le Caignec, Cedric, Davis, Erica, E, Stewart, Grant, S
المساهمون: University of Birmingham Birmingham, Ann & Robert H. Lurie Children's Hospital of Chicago, Government College University of Faisalabad (GCUF), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Service de génétique médicale - Unité de génétique clinique Nantes, Université de Nantes (UN)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Novo Nordisk Foundation Center for Protein Research (CPR), Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), University of Minnesota System (UMN), University of Sussex, National Institute of Genetics Mishima, Japan (NIG), Duke University Medical Center, University of the Witwatersrand Johannesburg (WITS), MRC Institute of Genetics and Molecular Medicine Edinburgh (IGMM), University of Edinburgh (Edin.)-Medical Research Council, King‘s College London, Boehringer Ingelheim, Universidad Nacional Autónoma de México = National Autonomous University of Mexico (UNAM), Radboud University Nijmegen, Maastricht University Medical Centre (MUMC), Maastricht University Maastricht, Research Organization of Information and Systems, National Institute of Polar Research Tokyo (NiPR), Division of Medical & Molecular Genetics, Department of Pediatrics, Jichi Medical University Tochigi-Ken, Japan, University of California San Diego (UC San Diego), University of California (UC), Hospital Infantil Universitario Niño Jesús (HIUNJ), University of Texas Health Science Center at San Antonio San Antonio, Tx, USA, Trinity College Dublin, Service Génétique Médicale CHU Toulouse, Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Toulouse NeuroImaging Center (ToNIC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), R01 GM134681/GM/NIGMS NIH HHS/United States MC_UU_00007/5/MRC_/Medical Research Council/United Kingdom R35 GM141805/GM/NIGMS NIH HHS/United States MR/P018955/1/MRC_/Medical Research Council/United Kingdom R01 MH106826/MH/NIMH NIH HHS/United States
المصدر: ISSN: 2041-1723.
مصطلحات موضوعية: MESH: Cell Cycle Proteins / genetics, MESH: Cell Cycle Proteins / metabolism, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: Chromosomes / metabolism, MESH: DNA Repair / genetics, MESH: DNA-Binding Proteins / metabolism, MESH: Genomic Instability, MESH: Humans, MESH: Microcephaly / genetics, MESH: Ubiquitin-Protein Ligases / metabolism, [SDV]Life Sciences [q-bio]
Relation: info:eu-repo/semantics/altIdentifier/pmid/36333305; PUBMED: 36333305; PUBMEDCENTRAL: PMC9636423
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2Academic Journal
المؤلفون: Gehrmann, Ulf, Burbage, Marianne, Zueva, Elina, Goudot, Christel, Esnault, Cyril, Ye, Mengliang, Carpier, Jean-Marie, Burgdorf, Nina, Hoyler, Thomas, Suarez, Guadalupe, Joannas, Leonel, Heurtebise-Chrétien, Sandrine, Durand, Sylvère, Panes, Rébecca, Bellemare-Pelletier, Angélique, Sáez, Pablo, J, Aprahamian, Fanny, Lefevre, Deborah, Adoue, Véronique, El Aabidine, Amal Zine, Muhammad, Maqbool, Hivroz, Claire, Joffre, Olivier, Cammas, Florence, Marie, Kroemer, Guido, Gagnon, Etienne, Andrau, Jean-Christophe, Amigorena, Sebastian
المساهمون: Immunité et cancer (U932), Institut Curie Paris -Institut National de la Santé et de la Recherche Médicale (INSERM), AstraZeneca, Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Métabolisme, Cancer et Immunité (CRC - UMR_S 1138), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Université de Montréal (UdeM), Institut de Recherche en Immunologie et en Cancérologie UdeM-Montréal (IRIC), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Karolinska University Hospital Stockholm, ANR-10-BLAN-1326,chromaTin,Dynamique de la chromatine au cours de l'activation des lympohocytes T: role de HP1(2010), ANR-11-LABX-0043,DCBIOL,Biologie des cellules dendritiques(2011), ANR-10-IDEX-0001,PSL,Paris Sciences et Lettres(2010), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014), ANR-10-INBS-0009,France Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010), ANR-11-LABX-0038,CelTisPhyBio,Des cellules aux tissus: au croisement de la Physique et de la Biologie(2011), ANR-16-CE18-0023,Healskin,Matrices pour la régénération et la cicatrisation cutanée(2016), ANR-10-EQPX-0003,ICGex,Equipement de biologie intégrative du cancer pour une médecine personnalisée(2010), ANR-11-LABX-0044,DEEP,Développement, Epigénèse, Epigénétique et potentiel de vie(2011), European Project: 340046,EC:FP7:ERC,ERC-2013-ADG,DCBIOX(2014)
المصدر: ISSN: 0027-8424.
مصطلحات موضوعية: T cells, TRIM28, autoimmunity, epigenetics, immunology, MESH: Animals, MESH: Autoimmunity / physiology, MESH: Cell Differentiation / physiology, MESH: Cell Plasticity / physiology, MESH: Cellular Reprogramming / genetics, MESH: Cellular Reprogramming / physiology, MESH: Chromobox Protein Homolog 5, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: Colon / pathology, MESH: Cytokines / metabolism, MESH: DNA-Binding Proteins / genetics, MESH: DNA-Binding Proteins / metabolism, MESH: Epigenesis, Genetic / physiology, MESH: Gene Expression Regulation, MESH: CD4-Positive T-Lymphocytes / metabolism, MESH: Cell Differentiation / genetics, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology
Relation: info:eu-repo/semantics/altIdentifier/pmid/31776254; info:eu-repo/grantAgreement/EC/FP7/340046/EU/Phagosome functions and antigen cross presentation in primary dendritic cells./DCBIOX; PUBMED: 31776254; PUBMEDCENTRAL: PMC6925996
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3Academic Journal
المؤلفون: Garcia-Luis, Jonay, Lazar-Stefanita, Luciana, Gutiérrez-Escribano, Pilar, Thierry, Agnès, Cournac, Axel, García, Alicia, Gonzalez, Sara, Sánchez, Mar, Jarmuz, Adam, Montoya, Alex, Dore, Marian, Kramer, Holger, Karimi, Mohammad, Antequera, Francisco, Koszul, Romain, Aragon, Luis
المساهمون: MRC London Institute of Medical Sciences (LMC), Régulation spatiale des Génomes - Spatial Regulation of Genomes, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Instituto de Biología Funcional y Genómica Salamanca, Spain (IBFG), Consejo Superior de Investigaciones Cientificas España = Spanish National Research Council Spain (CSIC)-Universidad de Salamanca, The work in the L.A. laboratory was supported by a Wellcome Trust Senior Investigator award to L.A. (100955, ‘Functional dissection of mitotic chromatin’) and the London Institute of Medical Research (LMS), which receives its core funding from the UK Medical Research Council. This research was further supported by funding from The European Research Council (R.K.), Agence Nationale pour la Recherche (R.K.) and the the Spanish Ministerio de Economía, Industria y Competitividad (BFU2017-89622-P, F.A.)., We thank the members of the L.A., R.K. and P.A. laboratories for fruitful discussions and advice.
المصدر: ISSN: 1545-9993.
مصطلحات موضوعية: Chromosome condensation, Chromatin remodelling, Nuclear organization, MESH: Cell Cycle Proteins / metabolism, MESH: Chromatin / metabolism, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: DNA-Binding Proteins / metabolism, MESH: High Mobility Group Proteins / metabolism, MESH: Protein Interaction Maps, MESH: Saccharomyces cerevisiae / cytology, MESH: Saccharomyces cerevisiae / metabolism, MESH: Saccharomyces cerevisiae Proteins / metabolism, MESH: Transcriptional Elongation Factors / metabolism, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/31582854; pasteur-02866764; https://pasteur.hal.science/pasteur-02866764; https://pasteur.hal.science/pasteur-02866764/document; https://pasteur.hal.science/pasteur-02866764/file/EMS84179.pdf; PUBMED: 31582854; PUBMEDCENTRAL: PMC6779571
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4Academic Journal
المؤلفون: Gutierrez-Aguilar, Ruth, Thompson, Abigail, Marchand, Nathalie, Dumont, Patrick, Woods, Stephen, C., de Launoit, Yvan, Seeley, Randy, J., Ulrich-Lai, Yvonne, M.
المساهمون: University of Cincinnati (UC), Hospital Infantil de México Federico Gómez (HIMFG), Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), This work was supported by the National Institutes of Health (grants DK093848 to RJS and R01 DK091425 to YMUL).
المصدر: ISSN: 0031-9384.
مصطلحات موضوعية: ETV5, stress, hypothalamic-pituitary-adrenocortical (HPA) axis, glucocorticoids, metabolism, MESH: Adrenal Glands/pathology, MESH: Animals, MESH: Receptors, Mineralocorticoid/genetics, Mineralocorticoid/metabolism, MESH: Anti-Inflammatory Agents/pharmacology, Vasopressin/genetics, Vasopressin/metabolism, MESH: Stress, Psychological/metabolism, Psychological/pathology, MESH: Thymus Gland/pathology, MESH: Transcription Factors/genetics, MESH: Transcription Factors/metabolism, MESH: Glucocorticoids/blood, MESH: Blood Glucose/physiology, MESH: Corticotropin-Releasing Hormone/blood, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, MESH: Dexamethasone/pharmacology, MESH: Gene Expression Regulation/genetics, MESH: Glucocorticoids/administration & dosage, MESH: Hypothalamo-Hypophyseal System/metabolism, MESH: Insulin/blood, MESH: Mice
Relation: info:eu-repo/semantics/altIdentifier/pmid/25813907; PUBMED: 25813907; PUBMEDCENTRAL: PMC4546891
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5Academic Journal
المؤلفون: Olguin-Lamas, Alejandro, Madec, Edwige, Hovasse, Agnes, Werkmeister, Elisabeth, Callebaut, Isabelle, Slomianny, Christian, Delhaye, Stephane, Mouveaux, Thomas, Schaeffer-Reiss, Christine, van Dorsselaer, Alain, Tomavo, Stanislas
المساهمون: Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Rôle des canaux ioniques membranaires et du calcium intracellulaire dans la physiopathologie de la prostate, Université de Lille, Sciences et Technologies-Institut National de la Santé et de la Recherche Médicale (INSERM), This research was funded by the Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche Medicale(INSERM), Institut Pasteur de Lille (IPL). The funders had no role in study design, data collection and analysis, decision to publish, or preparationof the manuscript., We would like to thank Dewailly E and Mortuaire M for excellent technical assistance, especially in the earlier phase of this study. We acknowledge Drs Harb O and Roos DS (University of Pennsylvania) for providing the nucleotide sequence of T. gondii rDNA 18S. We are indebted to Drs Hakimi A and Leprince D for providing nucleosome and antibodies specific to core histones, respectively. Special thanks to Drs Gordon Langsley and Robert Walker for critical reading the manuscript and all members of the lab for fruitful discussions.
المصدر: ISSN: 1553-7366.
مصطلحات موضوعية: MESH: Antibodies, Protozoan, MESH: Cell Nucleolus/genetics, MESH: Proteomics, MESH: Protozoan Proteins/biosynthesis, MESH: Cell Nucleolus/metabolism, MESH: Protozoan Proteins/chemistry, MESH: Protozoan Proteins/genetics, MESH: Protozoan Proteins/metabolism, MESH: Regulatory Sequences, Nucleic Acid, MESH: Reverse Transcriptase Polymerase Chain Reaction, MESH: Ribosomes/metabolism, MESH: Sequence Analysis, Protein, MESH: Histones/metabolism, MESH: Staining and Labeling, MESH: Tacrolimus Binding Proteins/chemistry, MESH: Toxoplasma/genetics, MESH: Chromatin/metabolism, MESH: Toxoplasma/metabolism, MESH: Toxoplasma/pathogenicity, MESH: Chromatin Immunoprecipitation, MESH: DNA-Binding Proteins/chemistry, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, MESH: Mass Spectrometry, MESH: Gene Silencing, MESH: High-Throughput Nucleotide Sequencing, MESH: Microscopy
Relation: info:eu-repo/semantics/altIdentifier/pmid/21483487; PUBMED: 21483487; PUBMEDCENTRAL: PMC3068996
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6
المؤلفون: Mohammad M. Karimi, Jonay García-Luis, Mar Sánchez, Luis Aragón, Luciana Lazar-Stefanita, Pilar Gutiérrez-Escribano, Adam Jarmuz, Axel Cournac, Alicia García, Alex Montoya, Sara Serrate González, Francisco Antequera, Holger B. Kramer, Marian Dore, Agnès Thierry, Romain Koszul
المساهمون: MRC London Institute of Medical Sciences (LMC), Régulation spatiale des Génomes - Spatial Regulation of Genomes, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Instituto de Biología Funcional y Genómica [Salamanca, Spain] (IBFG), Universidad de Salamanca-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), The work in the L.A. laboratory was supported by a Wellcome Trust Senior Investigator award to L.A. (100955, ‘Functional dissection of mitotic chromatin’) and the London Institute of Medical Research (LMS), which receives its core funding from the UK Medical Research Council. This research was further supported by funding from The European Research Council (R.K.), Agence Nationale pour la Recherche (R.K.) and the the Spanish Ministerio de Economía, Industria y Competitividad (BFU2017-89622-P, F.A.)., We thank the members of the L.A., R.K. and P.A. laboratories for fruitful discussions and advice., Wellcome Trust, Medical Research Council (UK), European Commission, European Research Council, Agence Nationale de la Recherche (France), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
المصدر: Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature Structural & Molecular Biology
Digital.CSIC. Repositorio Institucional del CSIC
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Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature structural & molecular biologyمصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Chromosomal Proteins, Non-Histone, MESH: Chromosomal Proteins, Non-Histone / metabolism, Cell Cycle Proteins, Chromatin remodelling, Saccharomyces cerevisiae, Article, MESH: Chromatin / metabolism, Chromosome segregation, 03 medical and health sciences, MESH: Cell Cycle Proteins / metabolism, 0302 clinical medicine, Structural Biology, Chromosome condensation, MESH: Saccharomyces cerevisiae / metabolism, Nucleosome, MESH: High Mobility Group Proteins / metabolism, Protein Interaction Maps, MESH: Saccharomyces cerevisiae / cytology, Molecular Biology, Metaphase, MESH: Protein Interaction Maps, 030304 developmental biology, 0303 health sciences, Nuclear organization, biology, Cohesin, Chemistry, High Mobility Group Proteins, Chromosome, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: DNA-Binding Proteins / metabolism, Chromatin, 3. Good health, Cell biology, DNA-Binding Proteins, Establishment of sister chromatid cohesion, Histone, MESH: Transcriptional Elongation Factors / metabolism, biology.protein, MESH: Saccharomyces cerevisiae Proteins / metabolism, Transcriptional Elongation Factors, biological phenomena, cell phenomena, and immunity, 030217 neurology & neurosurgery
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7
المؤلفون: Lise Secardin, William Vainchenker, Olivier Bernard, Alexander A. Ishchenko, Murat Saparbaev, Emna Mahfoudhi, Philippe Rameau, Véronique Della Valle, Ibtissam Talhaoui, Isabelle Plo, Xenia Cabagnols, Salem Abbes
المساهمون: Hématopoïèse normale et pathologique (UMR 1170 ), Université Paris-Sud - Paris 11 (UP11) - Institut Gustave Roussy (IGR) - Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'hématologie moléculaire et cellulaire, institut Pasteur de Tunis, Institut Pasteur de Tunis - Réseau International des Instituts Pasteur, Institut Gustave Roussy (IGR), Réparation de l’ADN (CNRS UMR 8200), This work was supported by grants from Agence Nationale de la Recherche (ANR-Blanc 2013 GERMPN) to IP and [ANR Blanc 2010 Project ANR-10-BLAN-1617] to IP and MS, Association pour la Recherche contre le Cancer (ARC) (ARC libre 2012) to IP, Electricité de France (http://www.edf.fr) RB 2014-26 to MS and Fondation de France (http://www.fondationdefrance.org) [#2012 00029161] to AAI. Labex GR-Ex (IP, WV) is funded by the program 'Investissements d’avenir'. EM was funded by INSERM/DGRST then a grant from Institut Pasteur from Tunis, Tunisia. LS were supported by Ph.D grants from the Cancéropôle Région Ile de France (DIM cellule souche). XC was supported by Ph.D MENRT grant. IT was supported by postdoctoral fellowship from the Fondation ARC (http://www.arc-cancer.net) PDF20110603195., ANR-Blanc 2013 GERMPN, GERMPN, ANR-10-BLAN-1617, EPIGENOME, Formation, dynamics and epigenetic functions of 5-hydroxymethylcytosine residues in DNA.(2010), Hématopoïèse normale et pathologique (U1170 Inserm), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Tunis El Manar (UTM), Laboratoire d'hématologie moléculaire et cellulaire (LR11IPT07), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Stabilité Génétique et Oncogenèse (UMR 8200), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Centre National de la Recherche Scientifique (CNRS), Plateforme imagerie et cytométrie (PFIC), Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse (AMMICa), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'Hématologie, Institut Pasteur de Tunis, This work was supported by grants from Agence Nationale de la Recherche (ANR-Blanc 2013 GERMPN) to IP and [ANR Blanc 2010 Project ANR-10-BLAN-1617] to IP and MS, Association pour la Recherche contre le Cancer (ARC) (ARC libre 2012) to IP, Electricité de France (http://www.edf.fr) RB 2014-26 to MS and Fondation de France (http://www.fondationdefrance.org) [#2012 00029161] to AAI. Labex GR-Ex (IP, WV) is funded by the program 'Investissements d’avenir'. EM was funded by INSERM/DGRST then a grant from Institut Pasteur from Tunis, Tunisia. LS were supported by Ph.D grants from the Cancéropôle Région Ile de France (DIM cellule souche). XC was supported by Ph.D MENRT grant. IT was supported by postdoctoral fellowship from the Fondation ARC., We thank the cytometry platform of Gustave Roussy (Y. Lecluse)., ANR-10-BLAN-1617,EPIGENOME,Formation, dynamics and epigenetic functions of 5-hydroxymethylcytosine residues in DNA.(2010), ANR-13-JSV1-0007,GERMPN,Etude des cas familiaux de néoplasmes myéloproliférifs: recherche des anomalies génétiques et de leurs fonctions.(2013), Pasteur Tunis, Institut, BLANC - Formation, dynamics and epigenetic functions of 5-hydroxymethylcytosine residues in DNA. - - EPIGENOME2010 - ANR-10-BLAN-1617 - BLANC - VALID, Jeunes Chercheuses et Jeunes Chercheurs - Etude des cas familiaux de néoplasmes myéloproliférifs: recherche des anomalies génétiques et de leurs fonctions. - - GERMPN2013 - ANR-13-JSV1-0007 - JC - VALID, Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: DNA Repair
DNA Repair, Elsevier, 2016, 43, pp.78-88. <10.1016/j.dnarep.2016.05.031>
DNA Repair, Elsevier, 2016, 43, pp.78-88. ⟨10.1016/j.dnarep.2016.05.031⟩
DNA Repair, 2016, 43, pp.78-88. ⟨10.1016/j.dnarep.2016.05.031⟩مصطلحات موضوعية: 0301 basic medicine, DNA Repair, Genetic instability, MESH: Fibroblasts/cytology, MESH: Tumor Suppressor Protein p53/metabolism, MESH: Fibroblasts/metabolism, MESH: Mutagenesis, MESH: Base Sequence, MESH: Thymine DNA Glycosylase/deficiency, Biochemistry, MESH: DNA Repair, Epigenesis, Genetic, S Phase, MESH: Thymine DNA Glycosylase/genetics, Mice, chemistry.chemical_compound, MESH: Genomic Instability, MESH: DNA-Binding Proteins/genetics, MESH: B-Lymphocytes/metabolism, MESH: Animals, MESH: Cytosine/metabolism, MESH: Epigenesis, Genetic, MESH: Megakaryocyte Progenitor Cells/cytology, MESH: B-Lymphocytes/cytology, B-Lymphocytes, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, MESH: Cytosine/analogs & derivatives, MESH: S Phase, Base excision repair, DNA-Binding Proteins, MESH: Proto-Oncogene Proteins/genetics, 5-hmC, CpG site, 5-Methylcytosine, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Cytosine, Guanine, MESH: Hydroxylation, TDG, Cell cycle, Biology, MESH: DNA-Binding Proteins/metabolism, Hydroxylation, Genomic Instability, Cell Line, Dioxygenases, 03 medical and health sciences, MESH: Tumor Suppressor Protein p53/genetics, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Proto-Oncogene Proteins, Animals, Humans, MESH: Mice, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Molecular Biology, Megakaryocyte Progenitor Cells, MESH: 5-Methylcytosine/analogs & derivatives, 5-Hydroxymethylcytosine, TET2, MESH: Humans, Base Sequence, MESH: Proto-Oncogene Proteins/metabolism, Mutagenesis, MESH: 5-Methylcytosine/metabolism, Cell Biology, Fibroblasts, Molecular biology, Thymine DNA Glycosylase, MESH: Cell Line, 030104 developmental biology, DNA demethylation, chemistry, DNA glycosylase, MESH: Megakaryocyte Progenitor Cells/metabolism, Tumor Suppressor Protein p53
وصف الملف: application/pdf
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8
المؤلفون: Marianne Burbage, Pablo J. Sáez, Deborah Lefevre, Thomas Hoyler, Amal Zine El Aabidine, Rébecca Panes, Guadalupe Suarez, Christel Goudot, Sebastian Amigorena, Jean-Marie Carpier, Mengliang Ye, Fanny Aprahamian, Claire Hivroz, Florence Cammas, Olivier Joffre, Véronique Adoue, Elina Zueva, Jean-Christophe Andrau, Angelique Bellemare-Pelletier, Sylvère Durand, Leonel Joannas, Etienne Gagnon, Maqbool Muhammad Ahmad, Guido Kroemer, Cyril Esnault, Ulf Gehrmann, Sandrine Heurtebise-Chrétien, Nina Burgdorf
المساهمون: Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Immunité et cancer (U932), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), AstraZeneca, Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Métabolisme, Cancer et Immunité (CRC - UMR_S 1138), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Université de Montréal (UdeM), Institut de Recherche en Immunologie et en Cancérologie [UdeM-Montréal] (IRIC), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Karolinska University Hospital [Stockholm], ANR-10-BLAN-1326,chromaTin,Dynamique de la chromatine au cours de l'activation des lympohocytes T: role de HP1(2010), ANR-11-LABX-0043,DCBIOL,Biologie des cellules dendritiques(2011), ANR-10-IDEX-0001,PSL,Paris Sciences et Lettres(2010), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014), ANR-10-INBS-0009,France-Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010), ANR-11-LABX-0038,CelTisPhyBio,Des cellules aux tissus: au croisement de la Physique et de la Biologie(2011), ANR-16-CE18-0023,Healskin,Matrices pour la régénération et la cicatrisation cutanée(2016), ANR-10-EQPX-0003,ICGex,Equipement de biologie intégrative du cancer pour une médecine personnalisée(2010), ANR-11-LABX-0044,DEEP,Développement, Epigénèse, Epigénétique et potentiel de vie(2011), European Project: 340046,EC:FP7:ERC,ERC-2013-ADG,DCBIOX(2014)
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Chromosomal Proteins, Non-Histone, MESH: Cellular Reprogramming / genetics, T-Lymphocytes, MESH: Cellular Reprogramming / physiology, [SDV]Life Sciences [q-bio], Cell Plasticity, MESH: Chromobox Protein Homolog 5, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Tripartite Motif-Containing Protein 28, T-Lymphocytes, Regulatory, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Epigenesis, Genetic, Histones, immunology, Mice, Phosphatidylinositol 3-Kinases, Immunology and Inflammation, 0302 clinical medicine, MESH: Animals, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, 0303 health sciences, Multidisciplinary, Effector, autoimmunity, Cell Differentiation, MESH: DNA-Binding Proteins / metabolism, Biological Sciences, MESH: Cell Differentiation / physiology, Cellular Reprogramming, MESH: Gene Expression Regulation, MESH: Cell Differentiation / genetics, Chromatin, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, PNAS Plus, Regulatory sequence, 030220 oncology & carcinogenesis, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: Epigenesis, Genetic / physiology, MESH: Cell Plasticity / physiology, Colon, T cell, Receptors, Antigen, T-Cell, T cells, Biology, 03 medical and health sciences, MESH: CD4-Positive T-Lymphocytes / metabolism, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Animals, Gene silencing, Gene Silencing, Epigenetics, 030304 developmental biology, Histone binding, MESH: DNA-Binding Proteins / genetics, epigenetics, TRIM28, MESH: Cytokines / metabolism, T-cell receptor, Gene Expression Regulation, Chromobox Protein Homolog 5, MESH: Autoimmunity / physiology, MESH: Colon / pathology, Transcriptome
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9Academic Journal
المؤلفون: Seehawer, Marco, Heinzmann, Florian, D’artista, Luana, Harbig, Jule, Roux, Pierre-François, Hoenicke, Lisa, Dang, Hien, Klotz, Sabrina, Robinson, Lucas, Doré, Grégory, Rozenblum, Nir, Kang, Tae-Won, Chawla, Rishabh, Buch, Thorsten, Vucur, Mihael, Roth, Mareike, Zuber, Johannes, Luedde, Tom, Sipos, Bence, Longerich, Thomas, Heikenwalder, Mathias, Wang, Xin Wei, Bischof, Oliver, Zender, Lars
المساهمون: Universitätsklinikum Tübingen - University Hospital of Tübingen, Eberhard Karls Universität Tübingen = University of Tübingen, Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe labellisée Ligue contre le Cancer, National Cancer Institute Bethesda (NCI-NIH), National Institutes of Health Bethesda, MD, USA (NIH), Universität Zürich Zürich = University of Zurich (UZH), Universitätsklinikum RWTH Aachen - University Hospital Aachen Aachen, Germany (UKA), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), Vienna Biocenter - VBC Austria, Heidelberg University Hospital Heidelberg, German Cancer Research Center - Deutsches Krebsforschungszentrum Heidelberg (DKFZ), German Cancer Consortium Heidelberg (DKTK), This work was supported by the ERC Consolidator Grant ‘CholangioConcept’ (to L.Z.), the German Research Foundation (DFG): grants FOR2314, SFB685, SFB/TR209 and the Gottfried Wilhelm Leibniz Program (to L.Z.). Further funding was provided by the German Ministry for Education and Research (BMBF) (e:Med/Multiscale HCC), the German Universities Excellence Initiative (third funding line: ‘future concept’), the German Center for Translational Cancer Research (DKTK), the German-Israeli Cooperation in Cancer Research (DKFZ-MOST) (to L.Z.) and the Intramural Research Program of the Centre for Cancer Research, National Cancer Institute, National Institutes of Health (to X.W.W.). The group of O.B. is supported by grants from ANR-BMFT, Fondation ARC pour la recherche sur le Cancer, INSERM, and the National Cancer Institute of the National Institutes of Health under Award Number R01CA136533. O.B. is a CNRS fellow., We thank E. Rist, P. Schiemann, C. Fellmeth, C.-J. Hsieh, D. Heide and J. Hetzer for technical help or assistance. We thank A. Weber for providing TLR2 and TLR4 knockout mice and W. S. Alexander and The Walter and Eliza Hall Institute of Medical Research for providing Mlklfl/fl mice. The Cas9n–p19Arf sgRNA vector was provided by W. Xue. We thank the c.ATG facility of Tuebingen University and CeGaT Tuebingen for exome sequencing and data analysis.
المصدر: ISSN: 0028-0836.
مصطلحات موضوعية: Cancer epigenetics, Cancer microenvironment, MESH: Animals, MESH: Apoptosis*/genetics, MESH: Cytokines/metabolism, MESH: DNA Transposable Elements/genetics, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, MESH: Disease Models, Animal, MESH: Epigenesis, Genetic/genetics, MESH: Female, MESH: Gene Expression Profiling, MESH: Genes, myc, ras, MESH: Carcinogenesis/genetics, MESH: Hepatocytes/metabolism, MESH: Hepatocytes/pathology, MESH: Humans, MESH: Liver Neoplasms/genetics, MESH: Liver Neoplasms/pathology, MESH: Male, MESH: Mice, MESH: Mosaicism, MESH: Necrosis*/genetics, MESH: Proto-Oncogene Proteins c-akt/genetics, MESH: Carcinoma, Hepatocellular/genetics
Relation: info:eu-repo/semantics/altIdentifier/pmid/30209397; hal-02348982; https://hal.science/hal-02348982; PUBMED: 30209397
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10
المؤلفون: Abigail M.K. Thompson, Randy J. Seeley, Yvan de Launoit, Yvonne M. Ulrich-Lai, Nathalie Marchand, Ruth Gutierrez-Aguilar, Stephen C. Woods, Patrick Dumont
المساهمون: University of Cincinnati (UC), Hospital Infantil de México Federico Gómez (HIMFG), Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), This work was supported by the National Institutes of Health (grants DK093848 to RJS and R01 DK091425 to YMUL)., Department of Psychiatry and Behavioral Neuroscience [UC, Cincinnati], Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Université de Lille, Droit et Santé, We thank K.M. Murphy from Washington University and the Howard Hughes Medical Institute for providing the ETV5 KO mouse line., Mécanismes de tumorigenèse et thérapies ciblées, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille
المصدر: Physiology and Behavior
Physiology and Behavior, Elsevier, 2015, 150, pp.38-42. ⟨10.1016/j.physbeh.2015.03.027⟩
Physiology and Behavior, Elsevier, 2016, 150, pp.38-42. ⟨10.1016/j.physbeh.2015.03.027⟩مصطلحات موضوعية: Blood Glucose, Receptors, Vasopressin, Vasopressin, Corticotropin-Releasing Hormone, MESH: Anti-Inflammatory Agents/pharmacology, [SDV]Life Sciences [q-bio], MESH: Receptors, Vasopressin/metabolism, Anti-Inflammatory Agents, Pituitary-Adrenal System, MESH: Dexamethasone/pharmacology, MESH: Mice, Knockout, Dexamethasone, MESH: Glucocorticoids/blood, Mice, Behavioral Neuroscience, stress, 0302 clinical medicine, Mineralocorticoid receptor, Glucocorticoid receptor, Hypothalamic–pituitary–adrenocortical (HPA) axis, MESH: Receptors, Vasopressin/genetics, Adrenal Glands, Insulin, MESH: Adrenal Glands/pathology, MESH: Animals, MESH: Thymus Gland/pathology, Vasopressin receptor, MESH: Receptors, Glucocorticoid/metabolism, Mice, Knockout, 0303 health sciences, Thymic involution, MESH: Transcription Factors/metabolism, glucocorticoids, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, hypothalamic-pituitary-adrenocortical (HPA) axis, MESH: Hypothalamo-Hypophyseal System/metabolism, MESH: Glucocorticoids/administration & dosage, DNA-Binding Proteins, Hypothalamus, Dexamethasone suppression test, MESH: Receptors, Glucocorticoid/genetics, Glucocorticoid, hormones, hormone substitutes, and hormone antagonists, medicine.drug, MESH: Receptors, Mineralocorticoid/genetics, Hypothalamo-Hypophyseal System, medicine.medical_specialty, 030209 endocrinology & metabolism, Experimental and Cognitive Psychology, MESH: Receptors, Mineralocorticoid/metabolism, Thymus Gland, Biology, MESH: Stress, Psychological/pathology, MESH: Pituitary-Adrenal System/pathology, Article, 03 medical and health sciences, Receptors, Glucocorticoid, Internal medicine, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Animals, MESH: Transcription Factors/genetics, MESH: Mice, 030304 developmental biology, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, ETV5, MESH: Gene Expression Regulation/genetics, MESH: Blood Glucose/physiology, Receptors, Mineralocorticoid, Endocrinology, Gene Expression Regulation, MESH: Insulin/blood, MESH: Corticotropin-Releasing Hormone/blood, metabolism, Stress, Psychological, Transcription Factors, MESH: Stress, Psychological/metabolism
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11Academic Journal
المؤلفون: Decorsière, Adrien, Toulas, Christine, Fouque, Françoise, Tilkin-Mariamé, Anne-Françoise, Selves, Janick, Guimbaud, Rosine, Chipoulet, Edith, Delmas, Caroline, Rey, Jean-Marc, Pujol, Pascal, Favre, Gilles, Millevoi, Stefania, Vagner, Stéphan
المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Claudius Regaud, Equipe 11-E.Moyal/C.Toulas, Service Anatomie et cytologie pathologiques CHU Toulouse, Pôle Biologie CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Département Oncologie médicale digestive CHU Toulouse, Pôle Maladies de l'appareil digestif CHU Toulouse, Hôpital Arnaud de Villeneuve CHRU Montpellier, Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Gustave Roussy (IGR), Université Paris-Sud - Paris 11 (UP11), This work was supported by INSERM and FRM (Equipe FRM, soutenue par la Fondation Recherche Médicale to S.V.) and the Groupe de Recherche de l’Institut Claudius Regaud (F.F., C.T., S.M., S.V., R.G.). A.D. was a recipient of a studentship from ARC (Association pour la recherche sur le cancer) and FRM., The authors sincerely thank Thomas Filleron for his help in statistical analyses, Chantal Darnau, Pauline Dejean and Isabelle Gitlaw for their efficient technical assistance.
المصدر: ISSN: 1538-4101.
مصطلحات موضوعية: MSH6, polyadenylation, Lynch syndrome, MESH: 3' Untranslated Regions, MESH: Cell Line, Tumor, MESH: Colorectal Neoplasms, Hereditary Nonpolyposis/genetics, Hereditary Nonpolyposis/metabolism, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, MESH: Gene Duplication, MESH: HCT116 Cells, MESH: HeLa Cells, MESH: Humans, MESH: Mutation, MESH: Polyadenylation, MESH: Polymorphism, Single Nucleotide, MESH: RNA, Messenger/metabolism, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.CAN]Life Sciences [q-bio]/Cancer
Relation: info:eu-repo/semantics/altIdentifier/pmid/22672937; hal-02364886; https://hal.science/hal-02364886; PUBMED: 22672937
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12Academic Journal
المؤلفون: Konradt, Christoph, Frigimelica, Elisabetta, Nothelfer, Katharina, Puhar, Andrea, Salgado-Pabon, Wilmara, Di Bartolo, Vincenzo, Scott-Algara, Daniel, Rodrigues, Cristina D, Sansonetti, Philippe, Phalipon, Armelle
المساهمون: Pathogénie Microbienne Moléculaire, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Biologie Cellulaire des Lymphocytes (BIOCELLY), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Régulation des Infections Rétrovirales, Institut Pasteur Paris (IP), Dynamique des Interactions Hôte-Pathogène - Dynamics of Host-Pathogen Interactions, Collège de France - Chaire Microbiologie et Maladies infectieuses, Collège de France (CdF (institution)), K.N. is a fellow from the Pasteur-Paris University International Doctoral Program. A. Puhar was supported first by EMBO long-term fellowship and is presently a Marie Curie fellow. W.S.-P. is funded by the Pasteur Foundation and the Philips Foundation. P.J.S. is a HHMI Foreign Scholar. The research leading to these results has received funding from the Institut Pasteur Transversal Research Program (PTR n° 251) and from the European Community's PEOPLE Seventh Framework Program under grant agreement EIMID IAPP - PIAP-GA-2008-217768., We warmly thank C. Parsot (Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur) for very helpful discussion, M.I. Thoulouze and A. Alcover (Unité de Biologie Cellulaire des Lymphocytes, Institut Pasteur) for sharing with us their expertise in T cells, G. Chicanne and B. Payrastre (INSERM U858, I2MR, CHU Rangueil) for their expertise in PI metabolism, and M. Arpin (Institut Curie, Paris, France) for her advice on the ERM proteins. From the G5 Dynamique des Interactions Hôte-Pathogènes, Institut Pasteur, L. Audry and A. Bobard were helpful in providing tools for the injection assay, and J. Enninga for some experimental design, discussion, and critical reading of the manuscript. T. Balla (National Institute of Child Health and Human Development, National Institutes of Health NIH ) kindly sent PLCδ1PH-RFP construct. We also thank Benoit Marteyn for his very efficient contribution in performing Shigella infection in the rabbit ileal model and processing samples for immunohistochemistry. We are also grateful to colleagues from the IMAGOPOLE platform of the Institut Pasteur. C.K. was supported by fellowships from the European Consortium PATHOGENOMICS, the Institut Pasteur Transversal Research Program n° 251, and the Howard Hughes Medical Institute (HHMI). E.F. holds a fellowship from the European Initiative for basic research in Microbiology and Infectious Diseases (EIMID Program).
المصدر: ISSN: 1931-3128 ; Cell Host and Microbe ; https://pasteur.hal.science/pasteur-00594631 ; Cell Host and Microbe, 2011, 9 (4), pp.263-72. ⟨10.1016/j.chom.2011.03.010⟩.
مصطلحات موضوعية: MESH: Bacterial Proteins / metabolism, MESH: Bacterial Secretion Systems, MESH: Chemokines / immunology, MESH: DNA-Binding Proteins / metabolism, MESH: Dysentery, Bacillary / genetics, Bacillary / metabolism, MESH: Fluorescent Antibody Technique, MESH: Host-Pathogen Interactions, MESH: Humans, MESH: Phosphatidylinositol 4,5-Diphosphate / deficiency, MESH: Phosphatidylinositol 4,5-Diphosphate / metabolism, MESH: Phosphatidylinositols / metabolism, MESH: Blotting, Western, MESH: Phosphoric Monoester Hydrolases / metabolism, MESH: Phosphorylation, MESH: Shigella flexneri / genetics, MESH: Shigella flexneri / metabolism, MESH: Transcription Factors / metabolism, MESH: CD4-Positive T-Lymphocytes / cytology, MESH: CD4-Positive T-Lymphocytes / immunology, MESH: CD4-Positive T-Lymphocytes / metabolism, MESH: CD4-Positive T-Lymphocytes / microbiology, MESH: Cell Line, MESH: Cell Membrane / chemistry, MESH: Cell Movement / immunology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
Relation: info:eu-repo/semantics/altIdentifier/pmid/21501826; pasteur-00594631; https://pasteur.hal.science/pasteur-00594631; PUBMED: 21501826
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13
المؤلفون: Christine Toulas, Caroline Delmas, Janick Selves, Rosine Guimbaud, Pascal Pujol, Anne-Françoise Tilkin-Mariamé, Stefania Millevoi, Gilles Favre, Françoise Fouque, Adrien Decorsière, Jean-Marc Rey, Edith Chipoulet, Stéphan Vagner
المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Claudius Regaud, CRLCC Institut Claudius Regaud, Equipe 11-E.Moyal/C.Toulas, Service d'anatomie et cytologie pathologiques [Purpan], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Département d'Oncologie Digestive [CHU Toulouse], Hôpital Arnaud de Villeneuve, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Gustave Roussy (IGR)-Université Paris-Sud - Paris 11 (UP11), Institut Gustave Roussy (IGR), Université Paris-Sud - Paris 11 (UP11), This work was supported by INSERM and FRM (Equipe FRM, soutenue par la Fondation Recherche Médicale to S.V.) and the Groupe de Recherche de l’Institut Claudius Regaud (F.F., C.T., S.M., S.V., R.G.). A.D. was a recipient of a studentship from ARC (Association pour la recherche sur le cancer) and FRM., The authors sincerely thank Thomas Filleron for his help in statistical analyses, Chantal Darnau, Pauline Dejean and Isabelle Gitlaw for their efficient technical assistance., Hôpital Arnaud de Villeneuve [CHRU Montpellier], Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]
المصدر: Cell Cycle
Cell Cycle, Taylor & Francis, 2012, 11 (13), pp.2578-2580. ⟨10.4161/cc.20625⟩مصطلحات موضوعية: Polyadenylation, 0302 clinical medicine, MRNA polyadenylation, MESH: DNA-Binding Proteins/genetics, Gene Duplication, Gene duplication, 3' Untranslated Regions, ComputingMilieux_MISCELLANEOUS, Genetics, 0303 health sciences, MESH: Polymorphism, Single Nucleotide, MESH: Gene Duplication, MESH: 3' Untranslated Regions, Lynch syndrome, MESH: Polyadenylation, DNA-Binding Proteins, 030220 oncology & carcinogenesis, MESH: Cell Line, Tumor, MESH: Mutation, Base pair, MESH: HCT116 Cells, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, MESH: DNA-Binding Proteins/metabolism, Polymorphism, Single Nucleotide, 03 medical and health sciences, MESH: Colorectal Neoplasms, Hereditary Nonpolyposis/metabolism, Cell Line, Tumor, medicine, Humans, RNA, Messenger, Molecular Biology, 030304 developmental biology, MESH: Humans, MESH: RNA, Messenger/metabolism, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Cell Biology, MSH6, medicine.disease, HCT116 Cells, Colorectal Neoplasms, Hereditary Nonpolyposis, MESH: Colorectal Neoplasms, Hereditary Nonpolyposis/genetics, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, MESH: HeLa Cells, Mutation, Developmental Biology, HeLa Cells
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14
المؤلفون: Agnès Hovasse, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Thomas Mouveaux, Alejandro Olguin-Lamas, Stanislas Tomavo, Edwige Madec, Christian Slomianny, Elisabeth Werkmeister, Stéphane Delhaye, Isabelle Callebaut
المساهمون: Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 (UGSF), Institut National de la Recherche Agronomique (INRA)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Rôle des canaux ioniques membranaires et du calcium intracellulaire dans la physiopathologie de la prostate, Université de Lille, Sciences et Technologies-Institut National de la Santé et de la Recherche Médicale (INSERM), This research was funded by the Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche Medicale(INSERM), Institut Pasteur de Lille (IPL). The funders had no role in study design, data collection and analysis, decision to publish, or preparationof the manuscript., We would like to thank Dewailly E and Mortuaire M for excellent technical assistance, especially in the earlier phase of this study. We acknowledge Drs Harb O and Roos DS (University of Pennsylvania) for providing the nucleotide sequence of T. gondii rDNA 18S. We are indebted to Drs Hakimi A and Leprince D for providing nucleosome and antibodies specific to core histones, respectively. Special thanks to Drs Gordon Langsley and Robert Walker for critical reading the manuscript and all members of the lab for fruitful discussions., Centre d’Infection et d’Immunité de Lille (CIIL) - U1019 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Recherche Agronomique (INRA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Thomas, Danielle
المصدر: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 3, p e1001328 (2011)
PLoS Pathogens, Public Library of Science, 2011, 7 (3), pp.e1001328. ⟨10.1371/journal.ppat.1001328⟩
PLoS Pathogens, 2011, 7 (3), pp.e1001328. ⟨10.1371/journal.ppat.1001328⟩مصطلحات موضوعية: Proteomics, MESH: Sequence Analysis, Protein, Protozoan Proteins, Antibodies, Protozoan, MESH: Toxoplasma/pathogenicity, MESH: DNA-Binding Proteins/chemistry, Regulatory Sequences, Nucleic Acid, Mass Spectrometry, MESH: Protozoan Proteins/chemistry, Histones, MESH: Cell Nucleolus/metabolism, Sequence Analysis, Protein, MESH: Reverse Transcriptase Polymerase Chain Reaction, Transcriptional regulation, MESH: Gene Silencing, Nuclear protein, MESH: Ribosomes/metabolism, Promoter Regions, Genetic, MESH: High-Throughput Nucleotide Sequencing, lcsh:QH301-705.5, MESH: Promoter Regions, Genetic, Regulation of gene expression, MESH: Chromatin Immunoprecipitation, MESH: Nuclear Proteins/metabolism, 0303 health sciences, MESH: Histones/metabolism, Reverse Transcriptase Polymerase Chain Reaction, MESH: Proteomics, 030302 biochemistry & molecular biology, High-Throughput Nucleotide Sequencing, Nuclear Proteins, Chromatin, 3. Good health, DNA-Binding Proteins, MESH: Staining and Labeling, Histone, Toxoplasma, MESH: Nuclear Proteins/genetics, Cell Nucleolus, Research Article, lcsh:Immunologic diseases. Allergy, Chromatin Immunoprecipitation, Immunology, MESH: Protozoan Proteins/genetics, MESH: Microscopy, Electron, Biology, MESH: DNA-Binding Proteins/metabolism, Microbiology, MESH: Toxoplasma/metabolism, Tacrolimus Binding Proteins, 03 medical and health sciences, Virology, Genetics, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Nucleosome, MESH: Antibodies, Protozoan, MESH: Regulatory Sequences, Nucleic Acid, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Gene Silencing, Molecular Biology/Chromatin Structure, Molecular Biology, MESH: Protozoan Proteins/metabolism, 030304 developmental biology, MESH: Protozoan Proteins/biosynthesis, MESH: Mass Spectrometry, MESH: DNA-Binding Proteins/genetics, Staining and Labeling, MESH: Nuclear Proteins/biosynthesis, Infectious Diseases/Protozoal Infections, Promoter, Molecular biology, MESH: Tacrolimus Binding Proteins/chemistry, MESH: Cell Nucleolus/genetics, MESH: Nuclear Proteins/chemistry, Microscopy, Electron, lcsh:Biology (General), Molecular Biology/Nucleolus and Nuclear Bodies, MESH: Chromatin/metabolism, biology.protein, Parasitology, MESH: Toxoplasma/genetics, lcsh:RC581-607, Chromatin immunoprecipitation, Ribosomes
وصف الملف: application/pdf
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15Academic Journal
المساهمون: Bactéries anaérobies et Toxines, Institut Pasteur Paris (IP), Génétique Moléculaire Bactérienne, This work was supported by a DRET Contract (0034056), a GPH 9 Institut Pasteur and a DGA Fellowship awarded to SR. We thank C. Dane for supporting this project., We thank A. Kolb for helpful discussion and B. Stiles for reading the manuscript.
المصدر: ISSN: 0950-382X.
مصطلحات موضوعية: MESH: Bacterial Proteins/genetics, MESH: Bacterial Proteins/physiology, MESH: DNA-Binding Proteins/metabolism, MESH: DNA-Directed RNA Polymerases/genetics, MESH: DNA-Directed RNA Polymerases/metabolism, MESH: DNA-Directed RNA Polymerases/physiology, MESH: Gene Expression Regulation, Bacterial, MESH: Molecular Sequence Data, MESH: Promoter Regions, Genetic, MESH: Protein Binding, MESH: Sigma Factor/genetics, MESH: Sigma Factor/physiology, MESH: Base Sequence, MESH: Tetanus Toxin/genetics, MESH: Trans-Activators/genetics, MESH: Trans-Activators/physiology, MESH: Botulinum Toxins/genetics, MESH: Clostridium botulinum/genetics, MESH: Clostridium botulinum/physiology, MESH: Clostridium tetani/genetics, MESH: Clostridium tetani/physiology, MESH: DNA, MESH: DNA-Binding Proteins/genetics, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/15612931; pasteur-02444103; https://pasteur.hal.science/pasteur-02444103; PUBMED: 15612931
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16Academic Journal
المؤلفون: Desjobert, Cécile, Richard de Soultrait, Vaea, Faure, Aurélie, Parissi, Vincent, Litvak, Simon, Tarrago-Litvak, Laura, Fournier, Michel
المساهمون: Laboratoire REGER : réplication et expression des génomes eucaryotes et rétroviraux (LRREGER), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), This work was supported by the Agence Nationale de Recherche contre le SIDA (ANRS), the Centre National de la Recherche Scientifique (CNRS), and the Université Victor Segalen Bordeaux 2. C.D. was supported by an MNERT doctoral fellowship, and V.R.S. and V.P. were supported by fellowships from the “Ensemble contre le SIDA” (Sidaction)., We thank J. F. Mouscadet (UMR-CNRS 8532, Villejuif, France) for the generous gift of the histidine-tagged HIV-1 IN plasmid constructions. The manuscript was edited by Ray Cooke (Department of Foreign Languages, University of Bordeaux 2).
المصدر: ISSN: 0006-2960.
مصطلحات موضوعية: MESH: Bacteriophage M13, MESH: Binding, Competitive, MESH: DNA-Binding Proteins/chemical synthesis, MESH: DNA-Binding Proteins/metabolism, MESH: HIV Integrase Inhibitors/chemical synthesis, MESH: Dimerization, MESH: HIV Integrase/chemistry, MESH: HIV Integrase/metabolism, MESH: HIV Integrase Inhibitors/chemistry, MESH: HIV Integrase Inhibitors/metabolism, MESH: Oligopeptides/chemical synthesis, MESH: Oligopeptides/chemistry, MESH: Substrate Specificity, MESH: Oligopeptides/metabolism, MESH: Peptide Library, MESH: Protein Binding, MESH: Transcription, Genetic, MESH: Capsid Proteins, MESH: Viral Fusion Proteins/chemical synthesis, MESH: Viral Fusion Proteins/metabolism, MESH: Virus Integration, MESH: Catalysis, MESH: Catalytic Domain, [SDV]Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
Relation: hal-02421530; https://hal.science/hal-02421530
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17Academic Journal
المؤلفون: Karlsson, S., Dupuy, B., Mukherjee, K., Norin, E., Burman, L., Akerlund, T.
المساهمون: Smittskydds Institutet - Swedish Institute for Infectious Disease Control Solna, Sweden (SMI), Public Health Agency of Sweden, Department of Microbiology Tumor and Cell Biology Stockholm, Karolinska Institutet Stockholm, Génétique Moléculaire Bactérienne, Institut Pasteur Paris (IP), Astrazeneca Research Foundation India, AstraZeneca, This work was supported by grants from the Vårdal Foundation, Stockholm, Sweden, and by a Ph.D. student grant provided by the Microbiology and Tumor biology Center at the Karolinska Institute., We are grateful for the excellent technical support provided by Anna-Karin Persson. We thank Nagraj Mani for kindly providing all pTUM plasmids. Protein data were obtained at the Protein Analysis Center, Karolinska Institute. The sequence data were produced by the Clostridium difficile Sequencing Group at the Sanger Center and can be obtained at http://www.sanger.ac.uk/Projects/C_difficile/.
المصدر: ISSN: 0019-9567.
مصطلحات موضوعية: MESH: Bacterial Proteins, MESH: Bacterial Toxins/genetics, MESH: Gene Expression Regulation, Bacterial, MESH: Humans, MESH: Promoter Regions, Genetic, MESH: Temperature, MESH: Transcription, MESH: Bacterial Toxins/metabolism, MESH: Butyric Acid/metabolism, MESH: Clostridium difficile/growth & development, MESH: Clostridium difficile/metabolism, MESH: DNA-Binding Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, MESH: Enterotoxins/genetics, MESH: Enterotoxins/metabolism, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Relation: info:eu-repo/semantics/altIdentifier/pmid/12654792; pasteur-02445950; https://hal-pasteur.archives-ouvertes.fr/pasteur-02445950; PUBMED: 12654792; PUBMEDCENTRAL: PMC152060
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18Academic Journal
المؤلفون: Jaubert, Jean, Cheng, Jun, Segre, Julia
المساهمون: National Human Genome Research Institute (NHGRI), We are very grateful to Adam Glick for providing us with the K5-tTA and TRE-lacZ mice, Jennie Owens for performing the electron microscopy, and Darryl Leja and Michael Cichanowski for assistance with the figures. Satyakam Patel, Natalia Martin and ZongFang Xi provided useful advice and criticisms at all stages of the work. We appreciate all of the assistance we received from Flora Heredia and the NHGRI ES and transgenic mouse core. A huge thanks goes to Paul Liu for his critical reading and suggestions to improve the lucidity of the manuscript.
المصدر: ISSN: 1011-6370 ; Development ; https://hal-pasteur.archives-ouvertes.fr/pasteur-02591729 ; Development, Palgrave Macmillan, 2003, 130 (12), pp.2767-2777. ⟨10.1242/dev.00477⟩.
مصطلحات موضوعية: KLF4, Epidermis, Permeability barrier, Perinatal mortality, Mouse, MESH: Animals, MESH: Cell Division / physiology, MESH: Transcription Factors / biosynthesis, MESH: Transcription Factors / genetics, MESH: Transcription Factors / metabolism, MESH: DNA-Binding Proteins / biosynthesis, MESH: DNA-Binding Proteins / genetics, MESH: DNA-Binding Proteins / metabolism, MESH: Epidermis / embryology, MESH: Epidermis / metabolism, MESH: Kruppel-Like Transcription Factors, MESH: Mice / embryology, MESH: Mice, Transgenic, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics
Relation: info:eu-repo/semantics/altIdentifier/pmid/12736219; pasteur-02591729; https://hal-pasteur.archives-ouvertes.fr/pasteur-02591729; PUBMED: 12736219
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المساهمون: Bactéries anaérobies et Toxines, Institut Pasteur [Paris], Génétique Moléculaire Bactérienne, This work was supported by a DRET Contract (0034056), a GPH 9 Institut Pasteur and a DGA Fellowship awarded to SR. We thank C. Dane for supporting this project., We thank A. Kolb for helpful discussion and B. Stiles for reading the manuscript., Institut Pasteur [Paris] (IP)
المصدر: Molecular Microbiology
Molecular Microbiology, Wiley, 2005, 55 (1), pp.235-249. ⟨10.1111/j.1365-2958.2004.04377.x⟩
Molecular Microbiology, 2005, 55 (1), pp.235-249. ⟨10.1111/j.1365-2958.2004.04377.x⟩مصطلحات موضوعية: Botulinum Toxins, Clostridium tetani, Operon, [SDV]Life Sciences [q-bio], MESH: Sigma Factor/genetics, MESH: Base Sequence, medicine.disease_cause, chemistry.chemical_compound, Clostridium, Sigma factor, MESH: DNA-Directed RNA Polymerases/metabolism, Clostridium botulinum, Botulism, Promoter Regions, Genetic, MESH: DNA-Directed RNA Polymerases/physiology, MESH: Clostridium botulinum/physiology, 0303 health sciences, biology, MESH: Sigma Factor/physiology, DNA-Directed RNA Polymerases, 3. Good health, DNA-Binding Proteins, MESH: DNA-Directed RNA Polymerases/genetics, MESH: Botulinum Toxins/genetics, Protein Binding, MESH: Gene Expression Regulation, Bacterial, DNA, Bacterial, MESH: Tetanus Toxin/genetics, Clostridium botulinum type A, Molecular Sequence Data, Sigma Factor, MESH: Bacterial Proteins/genetics, MESH: DNA-Binding Proteins/metabolism, Microbiology, MESH: Bacterial Proteins/physiology, MESH: Clostridium tetani/physiology, MESH: Trans-Activators/physiology, 03 medical and health sciences, Bacterial Proteins, Tetanus Toxin, MESH: Promoter Regions, Genetic, medicine, MESH: Protein Binding, TetR, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Molecular Biology, MESH: Clostridium tetani/genetics, 030304 developmental biology, MESH: DNA-Binding Proteins/genetics, MESH: Molecular Sequence Data, Base Sequence, MESH: Trans-Activators/genetics, 030306 microbiology, MESH: Clostridium botulinum/genetics, Gene Expression Regulation, Bacterial, biochemical phenomena, metabolism, and nutrition, medicine.disease, biology.organism_classification, Molecular biology, MESH: DNA, Bacterial, chemistry, Trans-Activators
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المؤلفون: Julia A. Segre, Jun Cheng, Jean Jaubert
المساهمون: National Human Genome Research Institute (NHGRI), We are very grateful to Adam Glick for providing us with the K5-tTA and TRE-lacZ mice, Jennie Owens for performing the electron microscopy, and Darryl Leja and Michael Cichanowski for assistance with the figures. Satyakam Patel, Natalia Martin and ZongFang Xi provided useful advice and criticisms at all stages of the work. We appreciate all of the assistance we received from Flora Heredia and the NHGRI ES and transgenic mouse core. A huge thanks goes to Paul Liu for his critical reading and suggestions to improve the lucidity of the manuscript.
المصدر: Development
Development, Palgrave Macmillan, 2003, 130 (12), pp.2767-2777. ⟨10.1242/dev.00477⟩مصطلحات موضوعية: Genetically modified mouse, Mouse, MESH: DNA-Binding Proteins / biosynthesis, MESH: Mice, Transgenic, Transgene, Kruppel-Like Transcription Factors, Mice, Transgenic, Biology, Transactivation, Kruppel-Like Factor 4, Mice, Krüppel, MESH: Transcription Factors / genetics, MESH: DNA-Binding Proteins / genetics, Animals, MESH: Animals, MESH: Cell Division / physiology, Molecular Biology, Transcription factor, MESH: Epidermis / embryology, Perinatal mortality, MESH: Transcription Factors / metabolism, MESH: DNA-Binding Proteins / metabolism, KLF4, Cell biology, MESH: Epidermis / metabolism, MESH: Transcription Factors / biosynthesis, DNA-Binding Proteins, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, MESH: Mice / embryology, In utero, Immunology, Ectopic expression, Permeability barrier, MESH: Kruppel-Like Transcription Factors, Epidermis, Cell Division, Developmental Biology, Transcription Factors