المؤلفون: Veninga, Alicia, De Simone, Ilaria, Heemskerk, Johan W. M., Ten Cate, Hugo, van der Meijden, Paola E. J.

المصدر: Veninga , A , De Simone , I , Heemskerk , J W M , Ten Cate , H & van der Meijden , P E J 2020 , ' Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding ' , Haematologica-the Hematology Journal , vol. 105 , no. 8 , pp. 2020-2031 . https://doi.org/10.3324/haematol.2019.235994

مصطلحات موضوعية: WISKOTT-ALDRICH SYNDROME, ACUTE MYELOID-LEUKEMIA, MYELOPROLIFERATIVE NEOPLASMS, ACCELERATES ATHEROSCLEROSIS, MEGAKARYOCYTE DEVELOPMENT, MYELODYSPLASTIC SYNDROMES, DEFICIENCY, MEGAKARYOPOIESIS, GENE, PROTEIN

وصف الملف: application/pdf

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/2a79e018-059f-4ba5-ad9d-1790ba522540
https://doi.org/10.3324/haematol.2019.235994
https://cris.maastrichtuniversity.nl/ws/files/89583355/Van_der_Meijden_2020_Clonal_hematopietic_mutations_linked_to.pdf

المؤلفون: Semerad, Craig L., Mercer, Elinore M., Inlay, Matthew A., Weissman, Irving L., Murre, Cornelis, Verma, Inder M.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2009 Feb 01. 106(6), 1930-1935.

URL الوصول: https://www.jstor.org/stable/40421700

المؤلفون: Osman, S, Taylor, KA, Allcock, N, Rainbow, RD, Mahaut-Smith, MP

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, T-TUBULE BIOGENESIS, MEGAKARYOCYTE DEVELOPMENT, BIOLOGICAL-MEMBRANES, CANALICULAR SYSTEM, PLATELET FORMATION, BLOOD-PLATELETS, BILAYER COUPLES, CARDIAC-MUSCLE, HEART-FAILURE, BONE-MARROW, Animals, Cell Surface Extensions, Cells, Cultured, Drug Evaluation, Preclinical, Estrenes, Male, Megakaryocytes, Myocytes, Cardiac, Phenothiazines, Pyrrolidinones, Rats, Wistar, Sulfonamides

Relation: Scientific Reports; http://hdl.handle.net/10044/1/53196; https://dx.doi.org/10.1038/srep18536

الاتاحة: http://hdl.handle.net/10044/1/53196
https://doi.org/10.1038/srep18536

المؤلفون: Paola E. J. van der Meijden, Alicia Veninga, Hugo ten Cate, Johan W. M. Heemskerk, Ilaria De Simone

المصدر: Haematologica

مصطلحات موضوعية: Blood Platelets, MYELOPROLIFERATIVE NEOPLASMS, Wiskott–Aldrich syndrome, PROTEIN, ACUTE MYELOID-LEUKEMIA, Disease, Review Article, WISKOTT-ALDRICH SYNDROME, Bioinformatics, 03 medical and health sciences, 0302 clinical medicine, MYELODYSPLASTIC SYNDROMES, medicine, Humans, MEGAKARYOPOIESIS, Platelet, Thrombocytosis, business.industry, Myelodysplastic syndromes, Hematopoietic Stem Cell Transplantation, Thrombosis, Hematology, medicine.disease, Hematopoietic Stem Cells, GENE, MEGAKARYOCYTE DEVELOPMENT, 3. Good health, Hematopoiesis, DEFICIENCY, medicine.anatomical_structure, Hemostasis, Mutation, Bone marrow, Stem cell, ACCELERATES ATHEROSCLEROSIS, business, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bda25724a006264084f6037231edd9
https://pubmed.ncbi.nlm.nih.gov/32554558

المؤلفون: Dulmovits, B. M., Hom, J., Narla, A., Mohandas, N., Blanc, L.

المصدر: Journal Articles

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Hematology, cell differentiation, erythropoiesis, glucocorticoids, human erythroid progenitors, pomalidomide, STEM-CELL FACTOR, DIAMOND-BLACKFAN ANEMIA, SELF-RENEWAL, BFU-E, IN-VITRO, CFU-E, MEGAKARYOCYTE DEVELOPMENT, LIN28B-LET-7-HMGA2 AXIS, ERYTHROBLASTIC ISLANDS, PERIPHERAL-BLOOD, Medical Molecular Biology

وصف الملف: application/pdf

Relation: https://academicworks.medicine.hofstra.edu/publications/3092; https://academicworks.medicine.hofstra.edu/context/publications/article/4093/viewcontent/CurrOpinHematol2017v24p159.pdf

الاتاحة: https://academicworks.medicine.hofstra.edu/publications/3092
https://academicworks.medicine.hofstra.edu/context/publications/article/4093/viewcontent/CurrOpinHematol2017v24p159.pdf

المصدر: Journal of Immunotherapy. 22(4):363-370

مصطلحات موضوعية: renal cell carcinoma, GROWTH-FACTOR, interleukin-6, malignant melanoma, NATURAL-KILLER, immunomodulation, I TRIAL, MEGAKARYOCYTE DEVELOPMENT, BLOOD T-CELLS, STIMULATING FACTOR, PROGENITOR CELLS, PHASE PROTEIN RESPONSE, human, ACTIVATED KILLER-CELLS, TUMOR-NECROSIS-FACTOR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::74c4a7e0b492cd8510909d392c7fe8a7
https://research.rug.nl/en/publications/b35bf3b5-5762-4db3-8b3e-c9af7bfbf108

المؤلفون: Ye, Buqing, Li, Chong, Yang, Zhao, Wang, Yanying, Hao, Junfeng, Wang, Li, Li, Yi, Du, Ying, Hao, Lu, Liu, Benyu, Wang, Shuo, Xia, Pengyan, Huang, Guanling, Sun, Lei, Tian, Yong, Fan, Zusen

المساهمون: Fan, ZS (reprint author), Chinese Acad Sci, Inst Biophys, Key Lab Infect & Immun, Beijing 100101, Peoples R China., Chinese Acad Sci, Inst Biophys, Key Lab Infect & Immun, Beijing 100101, Peoples R China., Chinese Acad Sci, Inst Biophys, Lab Anim Res Ctr, Beijing 100101, Peoples R China., Chinese Acad Sci, Inst Biophys, Ctr Biol Imaging, Beijing 100101, Peoples R China., Chinese Acad Sci, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China., Chinese Acad Sci, Inst Biophys, Beijing Noncoding RNA Lab, Beijing 100101, Peoples R China., Univ Chinese Acad Sci, Beijing 100049, Peoples R China., Peking Univ, Hosp 3, Dept Anesthesiol, Beijing 100191, Peoples R China.

المصدر: PubMed ; SCI

مصطلحات موضوعية: SPINDLE ASSEMBLY CHECKPOINT, HEMATOPOIETIC STEM-CELLS, AURORA-B KINASE, MEGAKARYOCYTE DEVELOPMENT, ALPHA-TUBULIN, PLATELET FORMATION, MAMMALIAN-CELLS, BETA-TUBULIN, MICE, POLYPLOIDIZATION

Relation: JOURNAL OF EXPERIMENTAL MEDICINE.2014,211,(12),2439-2454.; 651023; http://hdl.handle.net/20.500.11897/341663; WOS:000345268800015

الاتاحة: https://hdl.handle.net/20.500.11897/341663
https://doi.org/10.1084/jem.20141123

المصدر: Journal of Clinical Oncology. 13(10):2585-2593

مصطلحات موضوعية: MICE, INVITRO, INTERFERON-BETA-2, PHASE-I TRIAL, INVIVO, THROMBOCYTOPOIESIS, THROMBOPOIESIS, COLONY-STIMULATING FACTOR, PRIMATES, MEGAKARYOCYTE DEVELOPMENT

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::51da98e609d93927f6a3c3a71ae6e975
https://hdl.handle.net/11370/882a9c1d-10a2-45e7-b037-ce039c26983e

المصدر: Blood. 86(3):900-905

مصطلحات موضوعية: MICE, INVITRO, STIMULATING FACTOR, DIFFERENTIATION, LYMPHOMA CELL-LINES, PROGENITOR CELLS, PHASE PROTEIN RESPONSE, GROWTH, TUMOR-NECROSIS-FACTOR, MEGAKARYOCYTE DEVELOPMENT

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::2fc2fe4e512d1332b2d61cdf36060a54
https://hdl.handle.net/11370/04c05c4b-1f33-4d86-aaf2-082e1a7ff090

المصدر: Blood. 84(5):1434-1441

مصطلحات موضوعية: PROTEIN RESPONSE, GROWTH-FACTOR, ADVANCED MALIGNANCIES, PROGENITOR CELLS, FACTOR INVIVO, FACTOR-ALPHA, COLONY-STIMULATING FACTOR, BONE-MARROW CELLS, TUMOR-NECROSIS-FACTOR, MEGAKARYOCYTE DEVELOPMENT

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::3d4cda7f20c8c754a93d3a4b777a1eab
https://hdl.handle.net/11370/c75a9edf-d0b6-4950-a4f3-56ee755928fe

المؤلفون: Olthof, Sandra G., Fatrai, Szabolcs, Drayer, A. Lyndsay, Tyl, Monika R., Vellenga, Edo, Schuringa, Jan Jacob

المصدر: Olthof , S G , Fatrai , S , Drayer , A L , Tyl , M R , Vellenga , E & Schuringa , J J 2008 , ' Downregulation of signal transducer and activator of transcription 5 (STAT5) in CD34(+) cells promotes megakaryocytic development, whereas activation of STAT5 drives erythropoiesis ' , STEM CELLS , vol. 26 , no. 7 , pp. 1732-1742 . https://doi.org/10.1634/stemcells.2007-0899

مصطلحات موضوعية: megakaryocyte development, erythropoiesis, signal transducer and activator of transcription 5, hematopoietic lineage commitment, TRANSCRIPTION FACTOR GATA-1, HEMATOPOIETIC STEM-CELL, TYROSINE KINASE JAK2, POLYCYTHEMIA-VERA, SELF-RENEWAL, MYELOPROLIFERATIVE DISORDERS, STEM/PROGENITOR CELLS, LINEAGE COMMITMENT, MUTATION, PROGENITORS

الاتاحة: https://hdl.handle.net/11370/60f1b0e1-4a7e-481f-9e08-c9a41bae082a
https://research.rug.nl/en/publications/60f1b0e1-4a7e-481f-9e08-c9a41bae082a
https://doi.org/10.1634/stemcells.2007-0899

المؤلفون: Monika R. Tyl, Edo Vellenga, A. Lyndsay Drayer, Sandra Olthof, Szabolcs Fatrai, Jan Jacob Schuringa

المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL), Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: STEM CELLS, 26(7), 1732-1742. Wiley-Blackwell

مصطلحات موضوعية: Platelet Membrane Glycoprotein IIb, Myeloid, Cellular differentiation, Down-Regulation, Stem cell factor, Antigens, CD34, Biology, POLYCYTHEMIA-VERA, Megakaryocyte, Cell Line, Tumor, hemic and lymphatic diseases, medicine, STAT5 Transcription Factor, Humans, Progenitor cell, TYROSINE KINASE JAK2, MUTATION, Thrombopoietin, Thrombopoietin receptor, Stem Cell Factor, PROGENITORS, Stem Cells, LINEAGE COMMITMENT, STEM/PROGENITOR CELLS, GATA1, Cell Differentiation, Cell Biology, hematopoietic lineage commitment, Flow Cytometry, HEMATOPOIETIC STEM-CELL, Cell biology, megakaryocyte development, signal transducer and activator of transcription 5, SELF-RENEWAL, medicine.anatomical_structure, Cancer research, Molecular Medicine, RNA Interference, TRANSCRIPTION FACTOR GATA-1, MYELOPROLIFERATIVE DISORDERS, Megakaryocytes, Receptors, Thrombopoietin, erythropoiesis, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e962372ab8517f90b08a23c76ffac1
https://research.rug.nl/en/publications/60f1b0e1-4a7e-481f-9e08-c9a41bae082a

المؤلفون: Nieken, Judith, Mulder, Nanno, Pietens, Jacob, Limburg, Pieter, de Leij, Louis, de Vries, Elisabeth G. E.

المصدر: Nieken , J , Mulder , N , Pietens , J , Limburg , P , de Leij , L & de Vries , E G E 1999 , ' The modulatory impact of recombinant human interleukin-6 on the immune system of cancer patients ' , Journal of Immunotherapy , vol. 22 , no. 4 , pp. 363-370 .

مصطلحات موضوعية: interleukin-6, renal cell carcinoma, malignant melanoma, immunomodulation, human, TUMOR-NECROSIS-FACTOR, ACTIVATED KILLER-CELLS, PHASE PROTEIN RESPONSE, BLOOD T-CELLS, NATURAL-KILLER, MEGAKARYOCYTE DEVELOPMENT, STIMULATING FACTOR, PROGENITOR CELLS, GROWTH-FACTOR, I TRIAL

Relation: https://research.rug.nl/en/publications/b35bf3b5-5762-4db3-8b3e-c9af7bfbf108

الاتاحة: https://hdl.handle.net/11370/b35bf3b5-5762-4db3-8b3e-c9af7bfbf108
https://research.rug.nl/en/publications/b35bf3b5-5762-4db3-8b3e-c9af7bfbf108

المؤلفون: Pieter Limburg, Elisabeth G.E. de Vries, Lou F. M. H. de Leij, Jacob Pietens, Nanno Mulder, Judith Nieken

المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: Journal of Immunotherapy, 22(4), 363-370. LIPPINCOTT WILLIAMS & WILKINS

مصطلحات موضوعية: Male, Cancer Research, medicine.medical_treatment, immunomodulation, Leukocyte Count, Immunology and Allergy, ACTIVATED KILLER-CELLS, Melanoma, TUMOR-NECROSIS-FACTOR, biology, NATURAL-KILLER, Middle Aged, I TRIAL, Prognosis, Kidney Neoplasms, Recombinant Proteins, Monokine, Survival Rate, medicine.anatomical_structure, Cytokine, PHASE PROTEIN RESPONSE, Cytokines, Tumor necrosis factor alpha, Female, Antibody, Adult, renal cell carcinoma, GROWTH-FACTOR, Adolescent, Immunology, malignant melanoma, Immunoglobulins, Disease-Free Survival, Immune system, White blood cell, medicine, Humans, human, Carcinoma, Renal Cell, Aged, Pharmacology, business.industry, Interleukin-6, Tumor Necrosis Factor-alpha, Granulocyte-Macrophage Colony-Stimulating Factor, Immunotherapy, medicine.disease, Lymphocyte Subsets, MEGAKARYOCYTE DEVELOPMENT, BLOOD T-CELLS, STIMULATING FACTOR, PROGENITOR CELLS, biology.protein, business, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e689469e4126083ae86fca29654576f2
https://pubmed.ncbi.nlm.nih.gov/10404438

المؤلفون: Veldhuis, GJ, Willemse, PHB, Mulder, NH, Limburg, PC, deVries, EGE

المصدر: Veldhuis , GJ , Willemse , PHB , Mulder , NH , Limburg , PC & deVries , EGE 1996 , ' Potential use of recombinant human interleukin-6 in clinical oncology ' , Leukemia and Lymphoma , vol. 20 , no. 5-6 , pp. 373-& .

مصطلحات موضوعية: interleukin-6, cytokines, cancer, chemotherapy, immunotherapy, anemia, PHASE PROTEIN RESPONSE, MYELOMA-CELL GROWTH, MEGAKARYOCYTE DEVELOPMENT, KILLER-CELLS, MICE, DIFFERENTIATION, PRIMATES, INVIVO, PROLIFERATION, LEUKEMIA

Relation: https://research.rug.nl/en/publications/c2ae1275-5f8c-4db8-9c1c-24ac93367fca

الاتاحة: https://hdl.handle.net/11370/c2ae1275-5f8c-4db8-9c1c-24ac93367fca
https://research.rug.nl/en/publications/c2ae1275-5f8c-4db8-9c1c-24ac93367fca

المؤلفون: VELDHUIS, GJ, WILLEMSE, PHB, SLEIJFER, DT, VANDERGRAAF, WTA, GROEN, HJM, LIMBURG, PC, MULDER, NH, DEVRIES, EGE

المصدر: VELDHUIS , GJ , WILLEMSE , PHB , SLEIJFER , DT , VANDERGRAAF , WTA , GROEN , HJM , LIMBURG , PC , MULDER , NH & DEVRIES , EGE 1995 , ' TOXICITY AND EFFICACY OF ESCALATING DOSAGES OF RECOMBINANT HUMAN INTERLEUKIN-6 AFTER CHEMOTHERAPY IN PATIENTS WITH BREAST-CANCER OR NON-SMALL-CELL LUNG-CANCER ' , Journal of Clinical Oncology , vol. 13 , no. 10 , pp. 2585-2593 .

مصطلحات موضوعية: COLONY-STIMULATING FACTOR, PHASE-I TRIAL, MEGAKARYOCYTE DEVELOPMENT, MICE, PRIMATES, INVIVO, INVITRO, THROMBOCYTOPOIESIS, INTERFERON-BETA-2, THROMBOPOIESIS

Relation: https://research.rug.nl/en/publications/882a9c1d-10a2-45e7-b037-ce039c26983e

الاتاحة: https://hdl.handle.net/11370/882a9c1d-10a2-45e7-b037-ce039c26983e
https://research.rug.nl/en/publications/882a9c1d-10a2-45e7-b037-ce039c26983e

المؤلفون: NIEKEN, J, MULDER, NH, VELLENGA, E, LIMBURG, PC, PIERS, DA, DEVRIES, EGE

المصدر: NIEKEN , J , MULDER , NH , VELLENGA , E , LIMBURG , PC , PIERS , DA & DEVRIES , EGE 1995 , ' RECOMBINANT HUMAN INTERLEUKIN-6 INDUCES A RAPID AND REVERSIBLE ANEMIA IN CANCER-PATIENTS ' , Blood , vol. 86 , no. 3 , pp. 900-905 .

مصطلحات موضوعية: PHASE PROTEIN RESPONSE, TUMOR-NECROSIS-FACTOR, LYMPHOMA CELL-LINES, MEGAKARYOCYTE DEVELOPMENT, STIMULATING FACTOR, PROGENITOR CELLS, GROWTH, MICE, INVITRO, DIFFERENTIATION

Relation: https://research.rug.nl/en/publications/04c05c4b-1f33-4d86-aaf2-082e1a7ff090

الاتاحة: https://hdl.handle.net/11370/04c05c4b-1f33-4d86-aaf2-082e1a7ff090
https://research.rug.nl/en/publications/04c05c4b-1f33-4d86-aaf2-082e1a7ff090

المؤلفون: VANGAMEREN, MM, WILLEMSE, PHB, MULDER, NH, LIMBURG, PC, GROEN, HJM, VELLENGA, E, DEVRIES, EGE

المصدر: VANGAMEREN , MM , WILLEMSE , PHB , MULDER , NH , LIMBURG , PC , GROEN , HJM , VELLENGA , E & DEVRIES , EGE 1994 , ' EFFECTS OF RECOMBINANT HUMAN INTERLEUKIN-6 IN CANCER-PATIENTS - A PHASE I-II STUDY ' , Blood , vol. 84 , no. 5 , pp. 1434-1441 .

مصطلحات موضوعية: TUMOR-NECROSIS-FACTOR, COLONY-STIMULATING FACTOR, BONE-MARROW CELLS, MEGAKARYOCYTE DEVELOPMENT, ADVANCED MALIGNANCIES, PROTEIN RESPONSE, PROGENITOR CELLS, GROWTH-FACTOR, FACTOR INVIVO, FACTOR-ALPHA

الاتاحة: https://hdl.handle.net/11370/c75a9edf-d0b6-4950-a4f3-56ee755928fe
https://research.rug.nl/en/publications/c75a9edf-d0b6-4950-a4f3-56ee755928fe

المصدر: Leukemia and Lymphoma. 20(5-6)

مصطلحات موضوعية: interleukin-6, KILLER-CELLS, INVIVO, PROLIFERATION, PRIMATES, chemotherapy, anemia, cytokines, MEGAKARYOCYTE DEVELOPMENT, MICE, DIFFERENTIATION, PHASE PROTEIN RESPONSE, cancer, immunotherapy, LEUKEMIA, MYELOMA-CELL GROWTH

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::4ca3b2374e8b0ff127a1ed612394a076
https://research.rug.nl/en/publications/c2ae1275-5f8c-4db8-9c1c-24ac93367fca

المصدر: Leukemia and Lymphoma. 20(5-6):373-&

مصطلحات موضوعية: interleukin-6, KILLER-CELLS, INVIVO, PROLIFERATION, PRIMATES, chemotherapy, anemia, cytokines, MEGAKARYOCYTE DEVELOPMENT, MICE, DIFFERENTIATION, PHASE PROTEIN RESPONSE, cancer, immunotherapy, LEUKEMIA, MYELOMA-CELL GROWTH

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::dbb5299dc256df560cba6b96a1c16a9b
https://hdl.handle.net/11370/c2ae1275-5f8c-4db8-9c1c-24ac93367fca