-
1Academic Journal
المؤلفون: Ferrara Romeo, Iole, Martinez Rodriguez, Paula, Blasco , MA
المساهمون: Ministerio de Economía y Competitividad (España)
مصطلحات موضوعية: PROLIFERATOR-ACTIVATED RECEPTOR, GENE-EXPRESSION, TELOMERE DYSFUNCTION, MAMMALIAN TELOMERES, METABOLIC SYNDROME, LIPID HOMEOSTASIS, PPAR-ALPHA, LIVER, CARCINOGENESIS, HEPATOCARCINOGENESIS
Relation: https://doi.org/10.1371/journal.pone.0204909.; info:eu-repo/grantAgreement/ES/SAF2013-45111-R; PLoS One. 2018; 13 (10): e0204909.; http://hdl.handle.net/20.500.12105/6742; PloS one
-
2
المؤلفون: Rita Valador Fernandes, Marianna Feretzaki, Joachim Lingner
المصدر: Cell Cycle
article-version (VoR) Version of Recordمصطلحات موضوعية: Telomerase, Transcription, Genetic, r-loops, DNA repair, RAD51, homologous recombination, Review, length, mammalian telomeres, Biology, Shelterin Complex, break-induced replication, Homology directed repair, repeat-containing rna, Neoplasms, Animals, Humans, Molecular Biology, Telomere Shortening, Repetitive Sequences, Nucleic Acid, par-terra, distinct, Cell Cycle, terra, DNA replication, Recombinational DNA Repair, Telomere Homeostasis, DNA, rad51, Cell Biology, telomeres, Shelterin, recombination, Cell biology, Telomere, shelterin proteins, chromatin, RNA, Long Noncoding, Rad51 Recombinase, telomere elongation, R-Loop Structures, transcription, Homologous recombination, Signal Transduction, Developmental Biology
-
3Academic Journal
المؤلفون: Zimmer, Jutta, Tacconi, Eliana M. C., Folio, Cecilia, Badie, Sophie, Porru, Manuela, Klare, Kerstin, Tumiati, Manuela, Markkanen, Enni, Halder, Swagata, Ryan, Anderson, Jackson, Stephen P., Ramadan, Kristijan, Kuznetsov, Sergey G., Biroccio, Annamaria, Sale, Julian E., Tarsounas, Madalena
المساهمون: Institute for Molecular Medicine Finland, Sergey Kuznetsov / Principal Investigator, Genome Stability Group
مصطلحات موضوعية: DNA-DAMAGE, HOMOLOGOUS RECOMBINATION, SMALL-MOLECULE, MAMMALIAN TELOMERES, LIGAND RHPS4, HUMAN GENOME, HUMAN-CELLS, REPLICATION, CANCER, TUMORS, Biomedicine
وصف الملف: application/pdf
Relation: E.M.C.T. and C.F. contributed equally to this work. We are grateful to Peter Bouwman and Alexandra Duarte (NKI, Amsterdam), Sven Rottenberg (Vetsuisse, University of Bern), Marie-Paule Teulade-Fichou (Curie Institute, Paris), Steve West (CRUK Clare Hall Laboratories), Hyunsook Lee (Seoul National University), and Carmen D'Angelo (Regina Elena Cancer Institute, Italy) for valuable reagents and/or technical suggestions. Research in the S.P.J. lab is funded by Cancer Research UK program grant C6/A11224, the European Research Council, and the European Community Seventh Framework Program grant agreement number HEALTH-F2-2010-259893 (DDResponse). Core infrastructure funding was provided by Cancer Research UK grant C6946/A14492 and Wellcome Trust grant WT092096. S.P.J. receives salary from the University of Cambridge, supplemented by Cancer Research UK. Research in the K.R. lab is supported by Medical Research Council (MC_PC_12001/1), University of Oxford, and Swiss National Science Foundation (31003A_141197). Work in the A.B. lab is supported by Italian Association for Cancer Research (AIRC # # 11567). Work in the J.E.S. lab is supported by a central grant to the Laboratory of Molecular Biology, Cambridge from the Medical Research Council (U105178808). J.Z. is supported by a Cancer Research UK D.Phil. Studentship and E.M.C.T. by a Medical Research Council D.Phil. Studentship. Work in the M.T. lab is supported by Cancer Research UK, Medical Research Council, University of Oxford, and EMBO Young Investigator Program.; Zimmer , J , Tacconi , E M C , Folio , C , Badie , S , Porru , M , Klare , K , Tumiati , M , Markkanen , E , Halder , S , Ryan , A , Jackson , S P , Ramadan , K , Kuznetsov , S G , Biroccio , A , Sale , J E & Tarsounas , M 2016 , ' Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds ' , Molecular Cell , vol. 61 , no. 3 , pp. 449-460 . https://doi.org/10.1016/j.molcel.2015.12.004; http://hdl.handle.net/10138/223937; 941f4f70-c792-4c78-a07a-cb9f67ca1cf1; 84957429074; 000372325800012
الاتاحة: http://hdl.handle.net/10138/223937
-
4Academic Journal
المساهمون: 융합생명공학부, 10104775, Kim, KT
مصطلحات موضوعية: NUCLEAR RIBONUCLEOPROTEIN A1, STRAND ANNEALING ACTIVITY, CELL-CYCLE PROGRESSION, G-RICH STRAND, IN-VITRO, PROTEIN-KINASE, MAMMALIAN TELOMERES, OVERHANG GENERATION, DAMAGE CHECKPOINT, HUMAN-CHROMOSOMES
Relation: NUCLEIC ACIDS RESEARCH; 40; 17; 8499; 8518; SCI급, SCOPUS 등재논문; SCI; Biochemistry & Molecular Biology; 2015-OAK-0000026318; https://oasis.postech.ac.kr/handle/2014.oak/11846; 14175; NUCLEIC ACIDS RESEARCH, v.40, no.17, pp.8499 - 8518; 000309464300037; 2-s2.0-84866904458
-
5Academic Journal
المؤلفون: Lee, Jennifer J., Lee, Junyeop, Lee, Hyunsook
المساهمون: Lee, Hyunsook
مصطلحات موضوعية: BREAK-INDUCED REPLICATION, CANCER SUSCEPTIBILITY GENE, G-QUADRUPLEX, DNA-DAMAGE, FRAGILE SITES, MAMMALIAN TELOMERES, MOLECULAR-STRUCTURE, GENOME INSTABILITY, HISTONE CHAPERONE, BRCA2, Alternative lengthening of telomeres (ALT), Telomere maintenance mechanism (TMM), Telomeric recombination, Break-induced replication (BIR), Replication stress
Relation: Seminars in Cell and Developmental Biology, Vol.113, pp.88-96; https://hdl.handle.net/10371/179976; 000642446200010; 2-s2.0-85097451881; 121493
-
6
المؤلفون: Diego Megías, Alvaro Castells-Garcia, Isabel López-Silanes, Maria A. Blasco, Mario F. Fraga, Juan J Montero
المساهمون: Spanish Ministry of Economy and Competitiveness Projects, World Cancer Research Fund International, Botín Foundation, Ministerio de Economía y Competitividad (España), World Cancer Research Fund, Fundación Botín
المصدر: Repisalud
Instituto de Salud Carlos III (ISCIII)
Recercat. Dipósit de la Recerca de Catalunya
instname
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
Digital.CSIC. Repositorio Institucional del CSIC
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, CHROMATIN, Polycomb-Group Proteins, General Physics and Astronomy, Telomeric heterochromatin, RECOMBINATION, MAMMALIAN TELOMERES, Histones, Mice, Heterochromatin, LENGTH, Histone code, RNA, Small Interfering, EPIGENETIC REGULATION, lcsh:Science, In Situ Hybridization, Fluorescence, Mice, Knockout, Multidisciplinary, REPRESSIVE COMPLEX 2, R-LOOPS, Polycomb Repressive Complex 2, Telomere, Cell biology, Histone Code, Histone, Telomeres, RNA, Long Noncoding, STEM-CELLS, Science, Biotin, macromolecular substances, Biology, Methylation, Catalysis, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Telomere Homeostasis, Cell Line, Tumor, Animals, Humans, Biotinylation, Telomeric heterochromatin assembly, fungi, General Chemistry, DNA, HEK293 Cells, 030104 developmental biology, biology.protein, RNA, lcsh:Q, Heterochromatin protein 1, CRISPR-Cas Systems
وصف الملف: application/pdf
-
7
المؤلفون: Paula F. Martinez, Maria A. Blasco, Iole Ferrara-Romeo
المساهمون: Ministerio de Economía y Competitividad (España)
المصدر: PLoS ONE, Vol 13, Iss 10, p e0204909 (2018)
PLoS ONE
Repisalud
Instituto de Salud Carlos III (ISCIII)مصطلحات موضوعية: Male, 0301 basic medicine, LIVER, Physiology, Cancer Treatment, lcsh:Medicine, HEPATOCARCINOGENESIS, Biochemistry, MAMMALIAN TELOMERES, Histones, Mice, PROLIFERATOR-ACTIVATED RECEPTOR, Animal Cells, PPAR-ALPHA, Medicine and Health Sciences, Diethylnitrosamine, Age of Onset, lcsh:Science, Telomere Shortening, GENE-EXPRESSION, METABOLIC SYNDROME, Multidisciplinary, Chromosome Biology, Liver Diseases, Liver Neoplasms, CARCINOGENESIS, rap1 GTP-Binding Proteins, Phenotype, Nucleic acids, Telomeres, Oncology, Liver, Physiological Parameters, Hepatocellular carcinoma, Female, Cellular Types, Anatomy, Liver cancer, Research Article, Chromosome Structure and Function, endocrine system, Carcinoma, Hepatocellular, TELOMERE DYSFUNCTION, Gastroenterology and Hepatology, Carcinomas, Chromosomes, 03 medical and health sciences, Sex Factors, Gastrointestinal Tumors, Genetics, medicine, Carcinoma, Animals, Humans, Obesity, Cell Proliferation, business.industry, Cell growth, LIPID HOMEOSTASIS, Body Weight, lcsh:R, Cancers and Neoplasms, Biology and Life Sciences, Neoplasms, Experimental, Hepatocellular Carcinoma, Cell Biology, DNA, medicine.disease, Telomere, Fatty Liver, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Hepatocytes, Cancer research, DNA damage, lcsh:Q, Steatosis, Age of onset, business
-
8
المؤلفون: Zimmer, Jutta, Tacconi, Eliana M. C., Folio, Cecilia, Badie, Sophie, Porru, Manuela, Klare, Kerstin, Tumiati, Manuela, Markkanen, Enni, Halder, Swagata, Ryan, Anderson, Jackson, Stephen P., Ramadan, Kristijan, Kuznetsov, Sergey G., Biroccio, Annamaria, Sale, Julian E., Tarsounas, Madalena
المساهمون: University of Zurich, Tarsounas, Madalena, Jackson, Stephen [0000-0001-9317-7937], Apollo - University of Cambridge Repository, Institute for Molecular Medicine Finland, Sergey Kuznetsov / Principal Investigator, Genome Stability Group
مصطلحات موضوعية: Male, Time Factors, Mice, Nude, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Transfection, MAMMALIAN TELOMERES, HOMOLOGOUS RECOMBINATION, 1307 Cell Biology, Neoplasms, Biomarkers, Tumor, 1312 Molecular Biology, LIGAND RHPS4, HUMAN GENOME, Animals, Humans, DNA Breaks, Double-Stranded, Molecular Targeted Therapy, Picolinic Acids, Molecular Biology, Cell Proliferation, BRCA2 Protein, Dose-Response Relationship, Drug, BRCA1 Protein, HUMAN-CELLS, Intracellular Signaling Peptides and Proteins, 10079 Institute of Veterinary Pharmacology and Toxicology, Cell Biology, Telomere, CANCER, TUMORS, Xenograft Model Antitumor Assays, SMALL-MOLECULE, Tumor Burden, G-Quadruplexes, G2 Phase Cell Cycle Checkpoints, HEK293 Cells, DNA-DAMAGE, Drug Resistance, Neoplasm, REPLICATION, Mad2 Proteins, Aminoquinolines, 570 Life sciences, biology, RNA Interference, 3111 Biomedicine, Tumor Suppressor p53-Binding Protein 1
وصف الملف: 1-s2.0-S1097276515009387-main.pdf - application/pdf; application/pdf
-
9
المؤلفون: Sascha Feuerhahn, Nahid Iglesias, Antonio Porro, Andrea Panza, Joachim Lingner
المصدر: FEBS Letters; Vol 584
FEBS Lettersمصطلحات موضوعية: Yeast Telomeres, Telomerase, RNA, Untranslated, Telomeric repeat-containing RNAs, Transcription, Genetic, Chromosome Ends, Telomeric heterochromatin, Biochemistry, Structural Biology, Heterochromatin, Neoplasms, Mammals, Genetics, 0303 health sciences, 030302 biochemistry & molecular biology, RNA-Binding Proteins, Telomere, Non-coding RNA, Subtelomere, Chromatin, Cell biology, Terra, Transcription, DNA Replication, Cells, Biophysics, Repeat-Containing Rna, Saccharomyces cerevisiae, Biology, Dna Methylation, Chromosomes, 03 medical and health sciences, Saccharomyces-Cerevisiae, Animals, Humans, Messenger-Rna Decay, Molecular Biology, 030304 developmental biology, Quality-Control, Cell Biology, Mammalian Telomeres, Kinetics, Eukaryotic chromosome fine structure, RNA, DNA Damage
-
10
المؤلفون: Joachim Lingner, Brian Luke
المصدر: The EMBO Journal; Vol 28
The EMBO Journalمصطلحات موضوعية: DNA Replication, Telomerase, Telomeric repeat-containing RNAs, RNA, Untranslated, Heterochromatin, Chromosome Ends, non-coding RNA, Telomeric heterochromatin, Biology, telomerase, Models, Biological, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Messenger-Rna, Transcription (biology), Hnrnp A1, Saccharomyces-Cerevisiae, Animals, Humans, Molecular Biology, 030304 developmental biology, Repetitive Sequences, Nucleic Acid, Genetics, 0303 health sciences, General Immunology and Microbiology, General Neuroscience, TERRA, Telomere, Non-coding RNA, telomeres, Chromatin Assembly and Disassembly, Mammalian Telomeres, Human-Cells, Yeast, Chromatin, 030220 oncology & carcinogenesis, Focus Review, chromatin, Human Fibroblasts, Transcription, X-Chromosome
-
11Academic Journal
المؤلفون: Amiard, S, Olivier, M, Allain, E, Choi, K, Smith-Unna, R, Henderson, IR, White, CI, Gallego, ME
المساهمون: Choi, K
مصطلحات موضوعية: CHROMOSOME END PROTECTION, DOUBLE-STRAND BREAKS, ARABIDOPSIS-THALIANA, BINDING-PROTEINS, DNA-DAMAGE, DYSFUNCTIONAL TELOMERES, MAMMALIAN TELOMERES, IONIZING-RADIATION, DUPLEX REPLICATION, PROMOTES TELOMERE
Relation: NUCLEIC ACIDS RESEARCH; Biochemistry & Molecular Biology; https://oasis.postech.ac.kr/handle/2014.oak/38036; 17094; NUCLEIC ACIDS RESEARCH, v.29/42, no.19, pp.11979 - 11991; 000347689500020; 2-s2.0-84925283428
-
12Academic Journal
المؤلفون: Ogrocká, A., Polanská, P., Majerová, E., Janeba, Z. (Zlatko), Fajkus, J. (Jiří), Fojtová, M.
مصطلحات موضوعية: DNA methylation, cytosine methylation, mammalian telomeres
Relation: urn:pissn: 0305-1048; urn:eissn: 1362-4962; http://hdl.handle.net/11104/0233368
-
13Academic Journal
المؤلفون: Glover, Lucy, Alsford, Sam, Horn, David
المصدر: Glover , L , Alsford , S & Horn , D 2013 , ' DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes ' , PLoS Pathogens , vol. 9 , no. 3 , ARTN e1003260 . https://doi.org/10.1371/journal.ppat.1003260
مصطلحات موضوعية: CELL-CYCLE ARREST, CHECKPOINT, DELETION, HOMOLOGOUS RECOMBINATION, GENE-EXPRESSION SITE, PLASMODIUM-FALCIPARUM, CHROMOSOME, MAMMALIAN TELOMERES, YEAST, BRUCEI
-
14Academic Journal
المؤلفون: Ji, Guangzhen, Ruan, Weimin, Liu, Kai, Wang, Fang, Sakellariou, Despoina, Chen, Jijun, Yang, Yang, Okuka, Maja, Han, Jianyong, Liu, Zhonghua, Lai, Liangxue, Gagos, Sarantis, Xiao, Lei, Deng, Hongkui, Li, Ning, Liu, Lin
المساهمون: Liu, L (reprint author), Nankai Univ, Coll Life Sci, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China., Nankai Univ, Coll Life Sci, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China., China Agr Univ, Coll Biol Sci, State Key Lab Agrobiotechnol, Beijing 100094, Peoples R China., Acad Athens Greece BRFAA, Biomed Res Fdn, Ctr Basic Res 2, Genet Lab, Athens, Greece., Zhejiang Univ, Coll Anim Sci, Stem Cell & Dev Biol Res Ctr, Hangzhou 310003, Zhejiang, Peoples R China., Peking Univ, Coll Life Sci, Beijing 100871, Peoples R China., Univ S Florida, Coll Med, Dept Obstet & Gynecol, Tampa, FL USA., North East Agr Univ, Life Sci Coll, Harbin, Heilongjiang, Peoples R China., Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Key Lab Regenerat Biol, Guangzhou 510530, Guangdong, Peoples R China.
المصدر: SCI
مصطلحات موضوعية: PLURIPOTENT STEM-CELLS, MAMMALIAN TELOMERES, GENOMIC STABILITY, SOMATIC-CELLS, MINIATURE PIG, GENERATION, LENGTH, CIRCLES, MOUSE, DNA
Relation: PLOS ONE.2013,8,(9).; 812822; http://hdl.handle.net/20.500.11897/391089; WOS:000325423500009
-
15Academic Journal
مصطلحات موضوعية: MARROW FAILURE SYNDROMES, MAMMALIAN TELOMERES, EPIGENETIC REGULATION, TINF2 MUTATIONS, HUMAN CANCER, ICF SYNDROME, HETEROCHROMATIN, CELLS, TRANSCRIPTION, COHORT
Relation: INORGANIC CHEMISTRY Volume:51 Issue:2 Pages:757-759; http://ir.lib.ntust.edu.tw/handle/987654321/39166; http://ir.lib.ntust.edu.tw/bitstream/987654321/39166/-1/index.html
-
16Academic Journal
المؤلفون: Bermejo-Alvarez, P., Rizos, D., Rath, Detlef, Lonergan, P., Gutierrez-Adan, A.
مصطلحات موضوعية: article, Text, ddc:630, BOVINE, BULL SPERM, development, DEVELOPMENTAL RATE, DIFFERENTIATION, DNA, EMBRYOS, Female, GENE, GERMANY, IN-VITRO, LEVEL, LINK, MAMMALIAN TELOMERES, MESSENGER-RNA EXPRESSION, METABOLISM, methylation, MITOCHONDRIAL-DNA, MOUSE EMBRYOS, mRNA transcription, mtDNA, PREIMPLANTATION EMBRYOS, REPEATS, SEQUENCE, SEXUAL-DIMORPHISM, SPERM SEXING TECHNOLOGY, TELOMERE LENGTH
Relation: Physiological genomics -- Physiol Genomics -- 1094-8341 -- 2038823-8; https://doi.org/10.1152/physiolgenomics.00234.2007; https://www.openagrar.de/receive/fimport_mods_00000878; https://www.openagrar.de/servlets/MCRFileNodeServlet/fimport_derivate_00000878/SD2008348.pdf; http://physiolgenomics.physiology.org/content/32/2/264.abstract
-
17
المؤلفون: Patrick Reichenbach, Joachim Lingner, Sophie Redon
المصدر: Nucleic Acids Research
Nucleic Acids Research; Vol 38مصطلحات موضوعية: Telomerase, Telomeric repeat-containing RNAs, RNA, Untranslated, Chromosome Ends, Telomeric heterochromatin, Repeat-Containing Rna, Biology, Ligands, Cell Line, Association, 03 medical and health sciences, Telomerase RNA component, 0302 clinical medicine, Transcription (biology), Hnrnp A1, Genetics, Humans, Telomerase reverse transcriptase, 030304 developmental biology, Repetitive Sequences, Nucleic Acid, Cell Nucleus, 0303 health sciences, Nucleic Acid Enzymes, Anchor Site, Immortal Cells, Templates, Genetic, Dna, Telomere, Non-coding RNA, Molecular biology, Reverse-Transcriptase, Mammalian Telomeres, In-Vitro, 030220 oncology & carcinogenesis, Peptides
-
18Academic Journal
المساهمون: 생명과학과, 10184525, An, GH
مصطلحات موضوعية: TELOMERIC DNA-BINDING, CHROMOSOME END PROTECTION, SUSPENSION-CULTURE CELLS, ARABIDOPSIS-THALIANA, LENGTH REGULATION, MAMMALIAN TELOMERES, DAMAGING AGENTS, IN-VITRO, TO-END, PROTEIN
Relation: PLANT CELL; 19; 1770; 1781; SCI급, SCOPUS 등재논문; SCI; Biochemistry & Molecular Biology; Plant Sciences; Cell Biology; 2007-OAK-0000007055; https://oasis.postech.ac.kr/handle/2014.oak/23248; 7634; PLANT CELL, v.19, no.6, pp.1770 - 1781; 000248451900005; 2-s2.0-34547659702
-
19Academic Journal
مصطلحات موضوعية: Oncology, Genetics & Heredity, Chromosome Instability, Genomic Instability, Mammalian Telomeres, Breast-cancer, Protein, Mice, Abnormalities, Carcinoma, Gene, Pot1, 270199 Biochemistry and Cell Biology not elsewhere classified, 270201 Gene Expression, 270202 Genome Structure, 321015 Oncology and Carcinogenesis, C1, 730108 Cancer and related disorders
Relation: orcid:0000-0002-2830-9259
-
20Academic Journal
المؤلفون: Bekaert, Sofie, Derradji, Hanane, De Meyer, Tim, Michaux, Arlette, Buset, Jasmine, Neefs, Mieke, Mergeay, Max, Jacquet, Paul, Van Oostveldt, Patric, Baatout, Sarah
المصدر: DNA REPAIR ; ISSN: 1568-7864
مصطلحات موضوعية: Biology and Life Sciences, INDUCED APOPTOSIS, GERM-CELLS, MAMMALIAN TELOMERES, CELLULAR SENESCENCE, X-IRRADIATION, malformations, teratogenesis, organogenesis, gastrula, early development, rodents, irradiation, telomere length, p53, LENGTH, RADIATION, DYSFUNCTION, HYPERSENSITIVITY
وصف الملف: application/pdf
Relation: https://biblio.ugent.be/publication/320749; http://hdl.handle.net/1854/LU-320749; http://dx.doi.org/10.1016/j.dnarep.2005.05.010; https://biblio.ugent.be/publication/320749/file/2123561