المؤلفون: Maryam Taheri, Maryam Afzali Mehr, Hossein Ghafouri

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Alzheimer’s disease (AD), Cholinergic pathway, Agonist, M1 muscarinic acetylcholine receptor, Orthosteric site, Thiazolidine-2,4-dione (TZD), Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/a841dbea0aba45589ff6543222025fcf

المؤلفون: Ali Pourmotabbed, Razieh Naghizadeh, Farshad Moradpour, Mozhgan Veisi, Seyed Ershad Nedaei, Fatemeh Zarei, Zahra Salimi

المصدر: Research in Pharmaceutical Sciences, Vol 18, Iss 3, Pp 326-335 (2023)

مصطلحات موضوعية: ltp induction, maternal seizure, m1 muscarinic acetylcholine receptor, telenzepine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=3;spage=326;epage=335;aulast=Pourmotabbed; https://doaj.org/toc/1735-5362; https://doaj.org/toc/1735-9414

URL الوصول: https://doaj.org/article/15f1d271d5f64f4db3e9c61a676914af

المؤلفون: Dongxue Wang, Yunjin Yao, Shiqi Wang, Yifei Hou, Lanxue Zhao, Hao Wang, Hongzhuan Chen, Jianrong Xu

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7356

مصطلحات موضوعية: M1 muscarinic acetylcholine receptor, signaling bias, Gαq, β-arrestin, BRET, molecular docking

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms24087356

الاتاحة: https://doi.org/10.3390/ijms24087356

المؤلفون: Zhang, Yan, Long, Zhen, Guo, Zhimou, Wang, Zhiwei, Zhang, Xiuli, Ye, Richard D, Liang, Xinmiao, Civelli, Olivier

مصطلحات موضوعية: Neurosciences, Animals, CHO Cells, Coumaric Acids, Cricetulus, Drugs, Chinese Herbal, Humans, Molecular Structure, Muscarinic Antagonists, Plant Extracts, Plant Roots, Receptor, Muscarinic M1, Recombinant Proteins, Scopolia, Scopolia tangutica Maxim, Hydroxycinnamic acid amides, M1 muscarinic acetylcholine receptor, Plant Biology, Complementary and Alternative Medicine, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/085072zx

المؤلفون: Takao Mandai, Yuu Sako, Emi Kurimoto, Yuji Shimizu, Minoru Nakamura, Makoto Fushimi, Ryouta Maeda, Maki Miyamoto, Haruhide Kimura

المصدر: Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)

مصطلحات موضوعية: cooperativity, M1 muscarinic acetylcholine receptor, positive allosteric modulator, α‐synuclein, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/1996db5c1bb74209a2c1a0e72f2d9b18

المؤلفون: Yi, Jee Hyun, Whitcomb, Daniel, Park, Se Jin, Martinez Perez, Celia, Barbati, Saviana, Mitchell, Scott, Cho, Kwangwook

المصدر: Yi , J H , Whitcomb , D , Park , S J , Martinez Perez , C , Barbati , S , Mitchell , S & Cho , K 2020 , ' M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer's disease pathology ' , Brain Communications , vol. 2 , no. 2 , fcaa058 . https://doi.org/10.1093/braincomms/fcaa058

مصطلحات موضوعية: Alzheimer’s disease, M1 muscarinic acetylcholine receptor (mAChR), metabotropic glutamate receptor 5 (mGluR5), recognition memory

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/1983/0bb82389-6677-45bc-99f1-a840a52b8ad8
https://research-information.bris.ac.uk/en/publications/0bb82389-6677-45bc-99f1-a840a52b8ad8
https://doi.org/10.1093/braincomms/fcaa058
https://research-information.bris.ac.uk/ws/files/246752981/fcaa058.pdf

المؤلفون: Bradley, SJ, Bourgognon, J-M, Sanger, HE, Verity, N, Mogg, AJ, White, DJ, Butcher, AJ, Moreno, JA, Molloy, C, Macedo-Hatch, T, Edwards, JM, Wess, J, Pawlak, R, Read, DJ, Sexton, PM, Broad, LM, Steinert, JR, Mallucci, GR, Christopoulos, A, Felder, CC, Tobin, AB

مصطلحات موضوعية: memory loss, M1 muscarinic acetylcholine receptor, M1 mACh

Relation: http://hdl.handle.net/10871/33127; Journal of Clinical Investigation

الاتاحة: http://hdl.handle.net/10871/33127
https://doi.org/10.1172/JCI87526

المؤلفون: Martin, H.G., Bernabeu, A., Lassale, O., Bouille, C., Beurrier, C., Pelissier-Alicot, A.L., Manzoni, O.J.

المساهمون: Institut de Biologie du Développement de Marseille (IBDM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 1662-5102 ; Frontiers in Cellular Neuroscience ; https://hal.science/hal-01432731 ; Frontiers in Cellular Neuroscience, 2015, 9, pp.457. ⟨10.3389/fncel.2015.00457⟩.

مصطلحات موضوعية: CB1 receptor, M1 muscarinic acetylcholine receptor, ECB system, Long-term depression, Prefrontal cortex, Synaptic plasticity, [SDV.BC]Life Sciences [q-bio]/Cellular Biology

Relation: hal-01432731; https://hal.science/hal-01432731; https://hal.science/hal-01432731/document; https://hal.science/hal-01432731/file/fncel-09-00457%281%29.pdf

الاتاحة: https://hal.science/hal-01432731
https://hal.science/hal-01432731/document
https://hal.science/hal-01432731/file/fncel-09-00457%281%29.pdf
https://doi.org/10.3389/fncel.2015.00457

المؤلفون: Alastair J. H. Brown, Sophie J. Bradley, Fiona H. Marshall, Giles A. Brown, Kirstie A. Bennett, Jason Brown, Julie E. Cansfield, David M. Cross, Chris de Graaf, Brian D. Hudson, Louis Dwomoh, Jo(~(a))o M. Dias, James C. Errey, Edward Hurrell, Jan Liptrot, Giulio Mattedi, Colin Molloy, Pradeep J. Nathan, Krzysztof Okrasa, Greg Osborne, Jayesh C. Patel, Mark Pickworth, Nathan Robertson, Shahram Shahabi, Christoffer Bundgaard, Keith Phillips, Lisa M. Broad, Anushka V. Goonawardena, Stephen R. Morairty, Michael Browning, Francesca Perini, Gerard R. Dawson, John F. W. Deakin, Robert T. Smith, Patrick M. Sexton, Julie Warneck, Mary Vinson, Tim Tasker, Benjamin G. Tehan, Barry Teobald, Arthur Christopoulos, Christopher J. Langmead, Ali Jazayeri, Robert M. Cooke, Prakash Rucktooa, Miles S. Congreve, Malcolm Weir, Andrew B. Tobin

المساهمون: Brown, Alastair J. H., Bradley, Sophie J., Marshall, Fiona H., Brown, Giles A., Bennett, Kirstie A., Brown, Jason, Cansfield, Julie E., Cross, David M., de Graaf, Chri, Hudson, Brian D., Dwomoh, Loui, Dias, Jo(~(a))o M., Errey, James C., Hurrell, Edward, Liptrot, Jan, Mattedi, Giulio, Molloy, Colin, Nathan, Pradeep J., Okrasa, Krzysztof, Osborne, Greg, Patel, Jayesh C., Pickworth, Mark, Robertson, Nathan, Shahabi, Shahram, Bundgaard, Christoffer, Phillips, Keith, Broad, Lisa M., Goonawardena, Anushka V., Morairty, Stephen R., Browning, Michael, Perini, Francesca, Dawson, Gerard R., Deakin, John F. W., Smith, Robert T., Sexton, Patrick M., Warneck, Julie, Vinson, Mary, Tasker, Tim, Tehan, Benjamin G., Teobald, Barry, Christopoulos, Arthur, Langmead, Christopher J., Jazayeri, Ali, Cooke, Robert M., Rucktooa, Prakash, Congreve, Miles S., Weir, Malcolm, Tobin, Andrew B.

مصطلحات موضوعية: Alzheimer's disease, G protein coupled receptor, M1 muscarinic acetylcholine receptor, muscarinic receptor, neurodegeneration, prion disease, structural based drug design, Aged, 80 and over, Aging, Alzheimer Disease, Amino Acid Sequence, Animal, Blood Pressure, CHO Cell, Cholinesterase Inhibitor, Cricetulu, Crystallization, Disease Models, Dog, Donepezil, Electroencephalography, Female, HEK293 Cell, Heart Rate, Human, Male, Mice, Inbred C57BL, Models

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/34822784; volume:184; issue:24; firstpage:5886; lastpage:5901.e22; journal:CELL; http://hdl.handle.net/11582/331046; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85119605873; https://pubmed.ncbi.nlm.nih.gov/34822784/

الاتاحة: http://hdl.handle.net/11582/331046
https://doi.org/10.1016/j.cell.2021.11.001
https://pubmed.ncbi.nlm.nih.gov/34822784/

المؤلفون: Buiter, Hans JC, Windhorst, Albert D, Huisman, Marc C, Yaqub, Maqsood, Knol, Dirk L, Fisher, Abraham, Lammertsma, Adriaan A, Leysen, Josée E

مصطلحات موضوعية: PET imaging, agonist, [11C]AF150(S), G protein-coupled receptor, rat brain, M1 muscarinic acetylcholine receptor

Relation: http://www.ejnmmires.com/content/3/1/19

الاتاحة: http://www.ejnmmires.com/content/3/1/19

المؤلفون: Yuji Shimizu, Yuu Sako, Takao Mandai, Haruhide Kimura, Emi Kurimoto, Ryouta Maeda, Maki Miyamoto, Makoto Fushimi, Minoru Nakamura

المصدر: Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)

مصطلحات موضوعية: Allosteric modulator, cooperativity, RM1-950, Pharmacology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Memory improvement, Muscarinic acetylcholine receptor, M1 muscarinic acetylcholine receptor, Medicine, General Pharmacology, Toxicology and Pharmaceutics, Donepezil, α‐synuclein, business.industry, Dementia with Lewy bodies, Muscarinic acetylcholine receptor M1, medicine.disease, Neurology, 030220 oncology & carcinogenesis, positive allosteric modulator, Cholinergic, Therapeutics. Pharmacology, business, Acetylcholine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72150c40b53a4ad05b7794f62f164063
https://doaj.org/article/1996db5c1bb74209a2c1a0e72f2d9b18

المؤلفون: Takao, Mandai, Yuu, Sako, Emi, Kurimoto, Yuji, Shimizu, Minoru, Nakamura, Makoto, Fushimi, Ryouta, Maeda, Maki, Miyamoto, Haruhide, Kimura

المصدر: Pharmacology Research & Perspectives

مصطلحات موضوعية: Diarrhea, Male, Memory Disorders, Dose-Response Relationship, Drug, α‐synuclein, cooperativity, Receptor, Muscarinic M1, Scopolamine, Cholinergic Agents, CHO Cells, Original Articles, Rats, Disease Models, Animal, Mice, Cricetulus, Allosteric Regulation, positive allosteric modulator, M1 muscarinic acetylcholine receptor, Animals, Original Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::37e078f1c932cf86cd270bd3cd9e9cd6
https://pubmed.ncbi.nlm.nih.gov/31990455

المؤلفون: Fisher, Abraham, Bezprozvanny, Ilya, Wu, Lili, Ryskamp, Daniel A., Bar-Ner, Nira, Natan, Niva, Brandeis, Rachel, Elkon, Hanoch, Nahum, Victoria, Gershonov, Eitan, LaFerla, Frank M., Medeiros, Rodrigo

مصطلحات موضوعية: M1 muscarinic acetylcholine receptor, σ1 receptor, Alzheimer’s disease, AF710B, AF267B, AF series, Cognitive deficits, Memory, Disease modification, Amyloids, Tau protein, Neuroinflammation

الاتاحة: https://espace.library.uq.edu.au/view/UQ:613043

المؤلفون: Zhiwei Wang, Zhimou Guo, Xinmiao Liang, Xiuli Zhang, Richard D. Ye, Olivier Civelli, Zhen Long, Yan Zhang

المصدر: Zhang, Y; Long, Z; Guo, Z; Wang, Z; Zhang, X; Ye, RD; et al.(2016). Hydroxycinnamic acid amides from Scopolia tangutica inhibit the activity of M1 muscarinic acetylcholine receptor in vitro. Fitoterapia, 108, 9-12. doi: 10.1016/j.fitote.2015.11.007. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/085072zx
Fitoterapia, vol 108

مصطلحات موضوعية: 0301 basic medicine, Coumaric Acids, Scopolia, Chinese Herbal, Medicinal & Biomolecular Chemistry, Plant Biology, CHO Cells, Muscarinic Antagonists, Pharmacology, Plant Roots, Article, Cinnamic acid, Scopolia tangutica Maxim, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, Complementary and Alternative Medicine, Drug Discovery, Muscarinic acetylcholine receptor, M1 muscarinic acetylcholine receptor, medicine, Hydroxycinnamic acid amides, Animals, Humans, chemistry.chemical_classification, Molecular Structure, biology, Plant Extracts, Chemistry, Chinese hamster ovary cell, Receptor, Muscarinic M1, Neurosciences, Drugs, General Medicine, Muscarinic acetylcholine receptor M1, Hydroxycinnamic acid, biology.organism_classification, Recombinant Proteins, In vitro, 030104 developmental biology, Biochemistry, Muscarinic M1, Antispasmodic, Receptor, Drugs, Chinese Herbal, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff72af5d9e5efb00201cc481fc8bde88
http://www.escholarship.org/uc/item/085072zx

المؤلفون: Thi Mai Huong Nguyen

مصطلحات موضوعية: Basic pharmacology, Pharmaceutical sciences, Positive allosteric modulators, M1 muscarinic acetylcholine receptor, neurocognitive deficits

Relation: https://figshare.com/articles/thesis/Positive_allosteric_modulators_of_the_M1_muscarinic_acetylcholine_receptor_for_the_treatment_of_neurocognitive_deficits/21301371

الاتاحة: https://doi.org/10.26180/21301371.v1
https://figshare.com/articles/thesis/Positive_allosteric_modulators_of_the_M1_muscarinic_acetylcholine_receptor_for_the_treatment_of_neurocognitive_deficits/21301371

المؤلفون: Cheng, Yong, Yu, Long-Chuan

المساهمون: Yu, LC (reprint author), Peking Univ, Coll Life Sci, Neurobiol Lab, Beijing 100871, Peoples R China., Peking Univ, Coll Life Sci, Neurobiol Lab, Beijing 100871, Peoples R China., Peking Univ, Coll Life Sci, State Key Lab Biomembrane & Membrane Biotechnol, Beijing 100871, Peoples R China.

المصدر: SCI ; PubMed

مصطلحات موضوعية: Galanin, M1 muscarinic acetylcholine receptor, Alzheimer's disease, ERK, CHOLINERGIC BASAL FOREBRAIN, BETA-INDUCED TOXICITY, ALZHEIMERS-DISEASE, POTENTIAL PROTECTION, TRANSGENIC MICE, NUCLEUS BASALIS, RAT, HIPPOCAMPUS, ACTIVATION, PATHOLOGY

Relation: NEUROSCIENCE LETTERS.2015,590,161-165.; 650252; http://hdl.handle.net/20.500.11897/188308; WOS:000350925100031

الاتاحة: https://hdl.handle.net/20.500.11897/188308
https://doi.org/10.1016/j.neulet.2015.02.011

المؤلفون: Jiang, Shangtong, Li, Yanfang, Zhang, Cuilin, Zhao, Yingjun, Bu, Guojun, Xu, Huaxi, Zhang, Yun-Wu

مصطلحات موضوعية: Agonist, Alzheimer's disease, Amyloid, Cholinergic hypofunction, M1 muscarinic acetylcholine receptor, Tau

Relation: https://repository.hkust.edu.hk/ir/Record/1783.1-130597; Neuroscience Bulletin, v. 30, (2), April 2014, p. 295-307; https://doi.org/10.1007/s12264-013-1406-z; http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=1673-7067&rft.volume=30&rft.issue=2&rft.date=2014&rft.spage=295&rft.aulast=Jiang&rft.aufirst=Shangtong&rft.atitle=M1+muscarinic+acetylcholine+receptor+in+Alzheimer%27s+disease&rft.title=Neuroscience+Bulletin; http://www.scopus.com/record/display.url?eid=2-s2.0-84899926221&origin=inward; http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000334513200013

الاتاحة: https://repository.hkust.edu.hk/ir/Record/1783.1-130597
https://doi.org/10.1007/s12264-013-1406-z
http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=1673-7067&rft.volume=30&rft.issue=2&rft.date=2014&rft.spage=295&rft.aulast=Jiang&rft.aufirst=Shangtong&rft.atitle=M1+muscarinic+acetylcholine+receptor+in+Alzheimer%27s+disease&rft.title=Neuroscience+Bulletin
http://www.scopus.com/record/display.url?eid=2-s2.0-84899926221&origin=inward
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000334513200013

المؤلفون: Jones, Amanda L., Mowry, Bryan J., McLean, Duncan E., Mantzioris, Basil X., Pender, Michael P., Greer, Judith M.

مصطلحات موضوعية: Schizophrenia, Autoantibodies, Immunohistochemistry, Neurofilament medium (NFM), M1 muscarinic acetylcholine receptor, 2403 Immunology, 2723 Immunology and Allergy, 2728 Clinical Neurology, 2808 Neurology

Relation: orcid:0000-0003-3792-3768; orcid:0000-0003-4440-4309; Not set

الاتاحة: https://espace.library.uq.edu.au/view/UQ:325796

المؤلفون: Jiang, Shangtong, Wang, Yan, Ma, Qilin, Zhou, Aina, Zhang, Xian, Zhang, Yun-wu, 张云武

مصطلحات موضوعية: beta-Amyloid, beta-Site APP cleaving protein 1, Alzheimer's disease, Proteosomal degradation, M1 Muscarinic acetylcholine receptor

Relation: NEUROSCIENCE LETTERS,2012,515（2）：125-130; http://dx.doi.org/10.1016/j.neulet.2012.03.026; WOS:000303625000006; http://dspace.xmu.edu.cn/handle/2288/15474

الاتاحة: https://doi.org/10.1016/j.neulet.2012.03.026
http://dspace.xmu.edu.cn/handle/2288/15474

المؤلفون: Hans Jc Buiter, Albert D. Windhorst, Maqsood Yaqub, Marc C. Huisman, Josée E. Leysen, Abraham Fisher, Dirk L. Knol, Adriaan A. Lammertsma

المساهمون: Neuroscience Campus Amsterdam - Brain Imaging Technology, Radiology and nuclear medicine, Epidemiology and Data Science, CCA - Disease profiling, NCA - Brain imaging technology

المصدر: Buiter, H J C, Windhorst, A D, Huisman, M C, Yaqub, M M, Knol, D L, Fisher, A, Lammertsma, A A & Leysen, J E 2013, ' [11C]AF150(S), an agonist PET ligand for M1 muscarinic acetylcholine receptors ', EJNMMI Research, vol. 3, no. 1, pp. 19 . https://doi.org/10.1186/2191-219X-3-19
EJNMMI research, 3(1). Springer Berlin
EJNMMI Research, 3(1). Springer Berlin
Buiter, H J C, Windhorst, A D, Huisman, M C, Yaqub, M M, Knol, D L, Fisher, A, Lammertsma, A A & Leysen, J E 2013, ' [11C]AF150(S), an agonist PET ligand for M1 muscarinic acetylcholine receptors ', EJNMMI research, vol. 3, no. 1, pp. 19 . https://doi.org/10.1186/2191-219X-3-19
EJNMMI Research

مصطلحات موضوعية: Agonist, Pathology, medicine.medical_specialty, business.industry, medicine.drug_class, PET imaging, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Pharmacology, [11C]AF150(S), SDG 3 - Good Health and Well-being, rat brain, Muscarinic acetylcholine receptor M5, Muscarinic acetylcholine receptor, M1 muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, Medicine, Inverse agonist, Radiology, Nuclear Medicine and imaging, G protein-coupled receptor, business, agonist, Original Research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7f810ed7d5016f1b0266055f7f64c3
https://research.vumc.nl/en/publications/43ac846a-abaa-4b7f-97de-20951003097a