المؤلفون: Michael D Sacco, Lauren R Hammond, Radwan E Noor, Dipanwita Bhattacharya, Lily J McKnight, Jesper J Madsen, Xiujun Zhang, Shane G Butler, M Trent Kemp, Aiden C Jaskolka-Brown, Sebastian J Khan, Ioannis Gelis, Prahathees Eswara, Yu Chen

المصدر: eLife, Vol 13 (2024)

مصطلحات موضوعية: S. aureus, GpsB recognition motif, cell division, penicillin-binding protein, cell wall, EzrA, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/85579; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/bfed07d8cbee49deab96202e09ac50e1

المؤلفون: Yu Chen, Adam R. Renslo, M. Trent Kemp, Insung Na, Xiujun Zhang, Kyle DeFrees, Derek A. Nichols

المصدر: FEBS Letters. 595:2981-2994

مصطلحات موضوعية: Mutation, Cefotaxime, Hydrogen bond, Chemistry, Stereochemistry, Mutagenesis, Mutant, Biophysics, Cell Biology, medicine.disease_cause, Biochemistry, Structural Biology, Genetics, medicine, Nitrocefin, Enzyme kinetics, Molecular Biology, Function (biology), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3b7dcd70f060259df6f6764a170cf260
https://doi.org/10.1002/1873-3468.14215

المؤلفون: Michael D. Sacco, Lauren R. Hammond, Radwan E. Noor, Dipanwita Bhattacharya, Jesper J. Madsen, Xiujun Zhang, Shane G. Butler, M. Trent Kemp, Aiden C. Jaskolka-Brown, Sebastian J. Khan, Ioannis Gelis, Prahathees J. Eswara, Yu Chen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6c0c2d8b9c6e1d181b8709ade21ca036
https://doi.org/10.1101/2022.10.25.513704

المؤلفون: M V Vasantha Kumar, Radwan Ebna Noor, Ioannis Gelis, Ruslan Sanishvili, Orville A. Pemberton, H. Lee Woodcock, M. Trent Kemp, Yu Chen, Fiona L. Kearns

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Acylation, Avibactam, Molecular Conformation, Protonation, Crystallography, X-Ray, Catalysis, beta-Lactamases, Acid dissociation constant, Hydrolysis, chemistry.chemical_compound, Bacterial Proteins, Escherichia coli, chemistry.chemical_classification, Binding Sites, Multidisciplinary, Chemistry, Substrate (chemistry), Hydrogen-Ion Concentration, Biological Sciences, Enzyme, Protons, beta-Lactamase Inhibitors, Azabicyclo Compounds

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e35085197c6cad4aad3c2974c2f7b9d
https://doi.org/10.1073/pnas.1922203117

المؤلفون: Xochina ElHilali-Pollard, Kyle DeFrees, Adam R. Renslo, Ahmed Mohamed, M. Trent Kemp, Yu Chen, Xiujun Zhang

المصدر: Org Chem Front

مصطلحات موضوعية: chemistry.chemical_compound, 010405 organic chemistry, Chemistry, Stereochemistry, Amide, Organic Chemistry, Stacking, Serine hydrolase, Model system, 010402 general chemistry, 01 natural sciences, Article, 0104 chemical sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab1eac26518f79457586c760380e416
https://pubmed.ncbi.nlm.nih.gov/32774871

المؤلفون: Roman Manetsch, Tommy W. McGaha, M. Trent Kemp, Niranjan K. Namelikonda, Randy W. Larsen, Dennis E. Kyle, Lynn D. Blake, Adonis McQueen, Ala Azhari

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:4597-4600

مصطلحات موضوعية: Drug, 8-Aminoquinoline, Erythrocytes, Primaquine, media_common.quotation_subject, Plasmodium falciparum, 030231 tropical medicine, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Article, Antimalarials, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, parasitic diseases, Drug Discovery, Gametocyte, medicine, Humans, 030212 general & internal medicine, Malaria, Falciparum, Molecular Biology, Cellular localization, Fluorescent Dyes, media_common, Life Cycle Stages, biology, Chemistry, Organic Chemistry, Hep G2 Cells, biology.organism_classification, medicine.disease, Virology, Cytosol, Microscopy, Fluorescence, Aminoquinolines, Molecular Medicine, Malaria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c3648d0921c55c32ba24e461aa4d0d
https://doi.org/10.1016/j.bmcl.2017.09.030

المؤلفون: H. Lee Woodcock, Eric V. Anslyn, Fiona L. Kearns, Carrie Robart, Brette M. Chapin, M. Trent Kemp, Sai Lakshmana Vankayala, Joseph D. Larkin

المصدر: Journal of chemical information and modeling, 2019, Vol.59(5), pp.2150-2158 [Peer Reviewed Journal]
J Chem Inf Model

مصطلحات موضوعية: Models, Molecular, Fluorophore, General Chemical Engineering, Molecular Conformation, Fructose, Library and Information Sciences, 01 natural sciences, Article, chemistry.chemical_compound, 0103 physical sciences, Anthracene, Aqueous solution, 010304 chemical physics, Hydrogen bond, General Chemistry, Combinatorial chemistry, Boronic Acids, 0104 chemical sciences, Computer Science Applications, Solvent, 010404 medicinal & biomolecular chemistry, Spectrometry, Fluorescence, chemistry, Covalent bond, Amine gas treating, Boronic acid

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e5b8c45d507a8862122e020401e768
http://dro.dur.ac.uk/27761/1/27761.pdf

المؤلفون: Yu Chen, M. Trent Kemp, Eric M. Lewandowski

المصدر: Biochim Biophys Acta Proteins Proteom

مصطلحات موضوعية: 0301 basic medicine, Hydrogen, Protein Conformation, Low-barrier hydrogen bond, Enthalpy, Biophysics, chemistry.chemical_element, Steroid Isomerases, Saccharomyces cerevisiae, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Analytical Chemistry, Catalysis, Enzyme catalysis, Structure-Activity Relationship, 03 medical and health sciences, Delocalized electron, Animals, Humans, Molecular Biology, Bacteria, 030102 biochemistry & molecular biology, Chemistry, Hydrogen bond, Proteins, Hydrogen Bonding, Hydrogen atom, Plants, 0104 chemical sciences, Crystallography, Biocatalysis, Thermodynamics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767b00a6c20ee179f0524f09d52b4c66
https://doi.org/10.1016/j.bbapap.2020.140557

المؤلفون: M. Trent Kemp, Aleksandra Karolak, Christi L. Whittington, H. Lee Woodcock, Tarah A. Word, Arjan van der Vaart, Randy W. Larsen

المصدر: Chemical Physics Letters. 619:214-218

مصطلحات موضوعية: Aqueous solution, Ligand, Enthalpy, Photodissociation, Analytical chemistry, General Physics and Astronomy, Quantum yield, Calorimetry, 2,2'-Bipyridine, chemistry.chemical_compound, chemistry, Physical chemistry, Density functional theory, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3867237b8aba3a55f0f266a4acab0590
https://doi.org/10.1016/j.cplett.2014.11.012

المؤلفون: Francis C. Peterson, Amanda M. Nevins, Emmanuel W. Smith, Rongshi Li, Anthony E. Getschman, Brian F. Volkman, Yu Chen, M. Trent Kemp, Zhen Qiao, Yan Liu, Sai Lakshmana Vankayala

مصطلحات موضوعية: 0301 basic medicine, Chemokine, Receptors, CXCR4, Magnetic Resonance Spectroscopy, Stereochemistry, Ligands, Article, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Humans, Binding site, Receptor, G protein-coupled receptor, Virtual screening, Binding Sites, biology, Molecular Structure, Chemistry, Nuclear magnetic resonance spectroscopy, Small molecule, Chemokine CXCL12, 030104 developmental biology, Docking (molecular), 030220 oncology & carcinogenesis, biology.protein, Biophysics, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f8774060ff6d2aacb6e76381d5f5cc
https://europepmc.org/articles/PMC5600900/

المؤلفون: Aleksandra Karolak, Christi L. Whittington, Randy W. Larsen, Tarah A. Word, M. Trent Kemp, Arjan van der Vaart, H. Lee Woodcock

المصدر: Biophysical Journal. 106:477a-478a

مصطلحات موضوعية: chemistry.chemical_compound, Aqueous solution, Chemistry, Stereochemistry, Ligand, Kinetics, Polymer chemistry, Biophysics, Density functional theory, Acetonitrile, Small molecule, 2,2'-Bipyridine, Protein ligand

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98d81c42bc6f815a18294ee8947c1aa
https://doi.org/10.1016/j.bpj.2013.11.2699