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    المصدر: Drug development & registration; № 1 (2018); 114-133 ; Разработка и регистрация лекарственных средств; № 1 (2018); 114-133 ; 2658-5049 ; 2305-2066

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    Relation: https://www.pharmjournal.ru/jour/article/view/554/549; K. Modjarrad, V.S. Moorthy, P. Millett, P.S. Gsell, C. Roth, M.P. Kieny. Developing Global Norms for Sharing Data and Results during Public Health Emergencies // PLoS Med. 2016. V. 13(1). P. 1-5.; P. Vallance, A. Freeman, M. Stewart. Data Sharing as Part of the Normal Scientific Process: A View from the Pharmaceutical Industry // PLoS Med. 2016. V. 13(1). e1001936.; ‘Non-Lethal’ Weapons / Ed. By N. Davison. - 2009. 304 p.; Chemical Control. Regulation of Incapacitating Chemical Agent Weapons, Riot Control Agents and their Means of Delivery / Ed. by M. Crowley. - 2016. 378 p.; OPCW. URL: https://www.opcw.org/about-chemical-weapons/types-of-chemical-agent/nerve-agents/ (дата обращения 24.12.2017).; Herbicidal warfare. URL: https://en.wikipedia.org/wiki/Herbicidal_warfare (дата обращения 09.12.2017).; Конвенция о запрещении разработки, производства, накопления и применения химического оружия и его уничтожении. Официальный документ ООН и OPCW (ред. от 29.07.2005). URL: https://www.opcw.org/fileadmin/OPCW/CWC/CWC_ru.pdf (дата обращения 14.12.2017).; W.J. Zhang, F. Jiang, J.F. Ou. Global pesticide consumption and pollution: with China as a focus // Proceedings of the International Academy of Ecology and Environmental Sciences. 2011. V. 1(2). P. 125-144.; M. Roser, H. Ritchie. Fertilizer and Pesticides. Our World in Data. URL: https://ourworldindata.org/fertilizer-and-pesticides/#fertilizer-production (дата обращения 14.12.2017).; Basic and Clinical Toxicology of Organophosphorus Compounds / Ed. by M. Balali-Mood and M. Abdollahi. - London. Springer-Verlag, 2014. 257 p.; B. Madea, F. Mußhoff. Knock-Out Drugs: Their Prevalence, Modes of Action, and Means of Detection // Dtsch Arztebl Int. 2009. V. 106(20). P. 341-7.; K. Perry. New spate of attacks by sleeping gas gang, caravanners warned // The Telegraph. 01.09.2014. URL: http://www.telegraph.co.uk/news/uknews/crime/11068184/New-spate-of-attacks-by-sleeping-gas-gang-caravanners-warned.html (дата обращения 14.12.2017).; Brad Ringeisen. Battlefield Medicine. URL: https://www.darpa.mil/program/battlefield-medicine (дата обращения 14.12.2017).; J. Sanchez. Systems-Based Neurotechnology for Emerging Therapies (DARPA SUBNETS). URL: https://www.darpa.mil/program/systems-based-neurotechnology-for-emerging-therapies (дата обращения 14.12.2017).; A. Anighoro, J. Bajorath, G. Rastelli. Polypharmacology: Challenges and Opportunities in Drug Discovery // J. Med. Chem. 2014. V. 57 (19). P. 7874-7887.; K. Barnett, S.W. Mercer, M. Norbury, G. Watt. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study // The Lancet. 2012. V. 380. P. 37-43.; А.В. Соснов, Ф.М. Семченко, М.И. Власов, В.Н. Тохмахчи, А.А. Соснова. Развитие комплексной фармакотерапии сильной и средней боли. Ч. 1. Мультитаргетное комбинирование опиоидов и ненаркотических анальгетиков центрального действия // Разработка и регистрация лекарственных средств. 2017. №2 (19). С. 176-187.; S.O. Bachurin, E.F. Shevtsova, G.F. Makhaeva et al. Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment // Scientific Reports. 2017. P. 1-15. URL: http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5372361&blobtype=pdf (дата обращения 14.12.2017).; An Organophosphate Poisoning Antidote Capable of Crossing the Blood-Brain Barrier. UCSD Tech ID: 22601 / UC Case 2012-317-0. URL: https://techtransfer.universityofcalifornia.edu/NCD/22601.html (дата обращения 14.12.2017).; Z. Radic, R.K. Sit, Z. Kovarik, S. Berend,E. Garcia, L. Zhang, G. Amitai, C. Green, B. Radic, V.V. Fokin, K.B. Sharpless, P. Taylor. Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases // J Biol Chem. 2012. V. 6 287(15). P. 11798-11809.; Patent US 20150361060 A1. Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them / P. Taylor, Z. Radic, K. Barry. - 2015.; J.E. Chambers, E.C. Meek, H.W. Chambers. Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates // Ann NY Acad Sci. 2016. V. 1374(1). P. 52-58.; Y.J. Rosenberg, L. Mao, X. Jiang, J. Lees, L. Zhang, Z. Radic, P. Taylor. Postexposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor // Chem Biol Interact. 2017. V. 25(274). P. 50-57.; Opioid Therapy in the 21st Century. Second Edition / Ed. by H.S. Smith. - London: Oxford University Press, 2013. 306 p.; A. Kokate, X. Li, B. Jasti. Effect of Drug Lipophilicity and Ionization on Permeability Across the Buccal Mucosa: A Technical Note // AAPS PharmSciTech. 2008. V. 9 (2). P. 501-504.; A. Yassen, E. Olofsen, A. Dahan, M. Danhof. Pharmacokinetic-Pharmacodynamic Modeling of the Antinociceptive Effect of Buprenorphine and Fentanyl in Rats: Role of Receptor Equilibration Kinetics // The journal of pharmacology and experimental therapeutics. 2005. V. 313(3). P. 1136-1149.; J. Lotsch. Pharmacokinetic-Pharmacodynamic Modeling of Opioids // Journal of Pain and Symptom Management. 2005. V. 29 (5S). P. 90-103.; Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care / Ed. by A.D. Kaye and A.M. Kaye. - N.Y.: Springer, 2014. 904 p.; A. Andrés, M. Rosés, C. Ràfols, E. Bosch, S. Espinosa, V. Segarra, J.M. Huerta. Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts // Eur J Pharm Sci. 2015. V. 30(76). P. 181-191.; LogD Predictor. ChemAxon. URL: https://disco.chemaxon.com/apps/demos/logd/ (дата обращения 14.12.2017).; M. Danhof. Systems pharmacology - Towards the modeling of network interactions // European Journal of Pharmaceutical Sciences. 2016. V. 94. P. 4-14. URL: http://dx.doi.org/10.1016/ (дата обращения 10.12.2017).; Y. Hu, J. Bajorath. Entering the ‘big data’ era in medicinal chemistry: molecular promiscuity analysis revisited // Future Sci. OA. 2017. V. 3(2). FSO179.; Drug Research Advisor. Clarivate Analytics. URL: https://clarivate.com/products/drug-research-advisor/ (дата обращения 14.12.2017).; База данных Integrity. URL: https://clarivate.com/training/training-overview-ls/integrity/#quicktabs-live_training_tabs_integrity=2 (дата обращения 14.12.2017).; A. Williams, E. Baird. Special Considerations for the Treatment of Pain from Torture and War // Curr Anesthesiol Rep. 2016. V. 6. P. 319-326.; J. Breslow, A. Monrow, J. Daly, J. Meissier, J. Gauyhan, M. Alder, T. Eisenstein. Morphine not trauma sensitizes to systemic Acinetobacter baumannii infection // J NeuroImmune Pharmacol. 2011. V. 6(4). P. 551-65.; Morphine-Induced Immunosuppression, From Brain to Spleen. NIDA. URL: https://www.drugabuse.gov/news-events/nida-notes/2008/06/morphine-induced-immunosuppression-brain-to-spleen (дата обращения 14.12.2017).; P. Sacerdote, S. Franchi, A.E. Panerai. Non-analgesic effects of opioids: mechanisms and potential clinical relevance of opioid-induced immunodepression // Curr Pharm Des. 2012. V. 18(37). P. 6034-42.; S. Bimonte, A Barbieri, D. Rea et al. Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression // BioMed Research International. 2015. V. 2015, Article ID 161508. P. 1-8.; K. Gupta, S. Kshirsagar, L. Chang et al. Morphine Stimulates Angiogenesis by Activating Proangiogenic and Survivalpromoting Signaling and Promotes Breast Tumor Growth // Cancer Research. 2002. V. 62. P. 4491-4498.; А.В. Соснов, С.В. Садовников, Ф.М. Семченко, К.А. Руфанов, В.Н. Тохмахчи, А.А. Соснова, И.А. Тюрин. Сильнодействующие ненаркотические анальгетики как направление развития фармацевтики // Разработка и регистрация лекарственных средств. 2016. № 1(14). С. 196-206.; TCCC Tactical Combat Casualty Care Guidelines URL: https://www.itstactical.com/medcom/tccc-medcom/2014-tccc-tactical-combat-casualty-care-guidelines/ (дата обращения 14.12.2017).; F.K. Butler, R.S. Kotwal, C.C. Buckenmaier. A Triple-Option Analgesia Plan for Tactical Combat Casualty Care: TCCC Guidelines Change 13-04 // Journal of special operations medicine: a peer reviewed journal for SOF medical professionals. 2014. V. 14 (1). P. 13-25.; A.D. Fisher, B. Rippee, H. Shehan, C. Conklin, R.L. Mabry. Prehospital analgesia with ketamine for combat wounds: a case series // J Spec Oper Med. 2014. V. 14(4). P. 11-17.; A. Eremenko, L. Sorokina. Nefopam, ketoprofen and trimeperidine in analgesia // Annu Meet Eur Soc Anaesthesiol. 2014. Abst 14AP8-6.; M.A. Yudin, N.G. Vengerovich, G.S. Sagalov, M.S. Vahvijanen, V.N. Bykov, S.V. Chepur. Changes in Respiratory Function during Treatment with Combination of Analgesic Substances Trimeperidine and Dexmedetomidine // Bulletin of Experimental Biology and Medicine. 2016. V. 162 (2). P. 215-219.; M.S. Cepeda, D.B. Carr. Comparison of Morphine, Ketorolac, and Their Combination for Postoperative Pain. Results from a Large, Randomized, Double-blind Trial // Anesthesiology. 2005. V. 103. P. 1225-32.; E. Soleyman-Zomalan, S. Motov, A. Likourezos, V. Cohen, I. Pushkar, C. Fromm. Patterns of Ketorolac dosing by emergency physicians // World J Emerg Med. 2017. V. 8 (1). P. 43-46.; J.R. Fricke, D. Angelocci, K. Fox, D. McHugh, L. Bynum, J.P. Yee. Comparison of the efficacy and safety of ketorolac and meperidine in the relief of dental pain // J Clin Pharmacol. 1992. V. 32(4). P. 376-84.; Приказ Министерства здравоохранения РФ № 70н от 15 февраля 2013 г. «Об утверждении требований к комплектации лекарственными препаратами и медицинскими изделиями комплекта индивидуального медицинского гражданской защиты для оказания первичной медико-санитарной помощи и первой помощи». URL: http://www.mchs.gov.ru/document/446399 (дата обращения 14.12.2017).; Abuse-Deterrent Opioids - Evaluation and Labeling. Guidance for Industry / Food and Drug Administration. Center for Drug Evaluation and Research (CDER). 2015. 26 p.; Н.Г. Венгерович, М.А. Юдин, А.С. Никифоров, Г.С. Сагалов, Э.А. Рузанова, Н.В. Шперлинг, А.И. Венгеровский, И.А. Шперлинг, А.С. Макачеев. Влияние комбинации фентанила и дексмедетомидина на функции внешнего дыхания при острой кровопотере // Бюллетень сибирской медицины. 2017. V. 16(2). P. 96-104.; I.K. Khanna, S. Pillarisetti. Buprenorphine - an attractive opioid with underutilized potential in treatment of chronic pain // Journal of Pain Research. 2015. V. 8. P. 859-870.; C. Martin, A. De Baerdemaeker, J. Poelaert, A. Madder, R. Hoogenboom, S. Ballet. Controlled-release of opioids for improved pain management // Materials Today. V. 19, Number 9. 2016. P. 491-502.; D.A. Volpe, G.A. McMahon Tobin, R.D. Mellon, A.G. Katki, R.J. Parker, T. Colatsky, T.J. Kropp, S. Leigh Verbois. Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs // Regulatory Toxicology and Pharmacology. 2011. V. 59. P. 385-390.; B. Zhang, T. Zhang, A.W. Sromek, T. Scrimale, J.M. Bidlack, J.L. Neumeyer. Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors // Bioorg Med Chem. 2011. V. 19(9). P. 2808-2816.; L.E. Mather. Opioids: a pharmacologist’s delight // Clin Exp Pharmacol Physiol. 1995. V. 22. P. 833-836.; F. Medzihradsky, P.J. Emmerson, C.A. Mousigian. Lipophilicity of Opioids Determined by a Novel Micromethod // JPM. 1992. V. 27 (2). P. 67-69.; DrugBank database. URL: https://www.drugbank.ca/drugs (дата обращения 24.12.2017).; Small Animal Toxicology / Ed. by M.E. Peterson, P.A. Talcott. - 2006. 1190 p.; J.W. Mandema, D.R. Stanski. Population pharmacodynamic model for ketorolac analgesia // Clin Pharmacol Ther. 1996. V. 60(6). P. 619-35.; Critical review of Ketamine 34th ECDD 2006/4.3. URL: https://www.drugbank.ca/unearth/q?utf8=%E2%9C%93&searcher=drugs&query=mu-Opioid+Receptor+Agonists (дата обращения 26.12.2017).; E. Bostro, M. Hammarlund-Udenaes, U.S.H. Simonsson. Blood-Brain Barrier Transport Helps to Explain Discrepancies in In Vivo Potency between Oxycodone and Morphine // Anesthesiology. 2008. V. 108. P. 495-505.; J.K. Coller, L.L. Christrup, A.A. Somogyi. Role of active metabolites in the use of opioids // Eur J Clin Pharmacol. 2009. V. 65(2). P. 121-39.; J. Cory Kalvass, E.R. Olson, M.P. Cassidy, D.E. Selley, G.M. Pollack. Pharmacokinetics and Pharmacodynamics of Seven Opioids in P-Glycoprotein-Competent Mice: Assessment of Unbound Brain EC50, and Correlation of in Vitro, Preclinical, and Clinical Data // The journal of pharmacology and experimental therapeutics. 2007. V. 323(1). P. 346-355.; P.P. Palmer. Efficacy and Safety of Sublingual Sufentanil 30 mcg for the Management of Acute Pain Following Ambulatory Surgery. AcelRx Pharmaceuticals. 2016.; S. Belli, F. Assmus, B. Wagner, M. Honer, H. Fischer, F. Schuler, R. Alvarez-Sánchez. Estimation of Drug Binding to Brain Tissue: Methodology and in Vivo Application of a Distribution Assay in Brain Polar Lipids // Mol. Pharmaceutics. 2015. V. 12(12). P. 4529-4541.; S. Beni, G. Toth, B. Noszal, S. Hosztafi. Preparation of benzoate esters of morphine and its derivatives // Monatsh Chem. 2012. V. 143(10). P. 1431-1440.; Patent US 2017143839. Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof / T. Mickle, S. Guenther, G. Chi, J. Kanski, A.K. Martin, B. Bera. - 2017.; K. McWilliams, M. Fallon. Fast-acting fentanyl preparations and pain management // Q J Med. 2013. V. 106. P. 887-890.; Fentanyl Transdermal System (marketed as Duragesic) Information / FDA. URL: https://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafety-InformationforPatientsandProviders/ucm114961.htm (дата обращения 26.12.2017).; J.C. Scott, J.E. Cooke, D.R. Stanski. Electroencephalographic quantitation of opioid effect: comparative pharmacodynamics of fentanyl and sufentanil // Anesthesiol. 1991. V. 74. P. 34-42.; T.-J. Gan, P.P. Palmer, M.A. Royal. Sublingual Sufentanil, an “Ideal” Opioid for Acute and Breakthrough Pain: The Clinical Importance of CST½ and t½ke0. Poster presentation at the American Pain Society 2014 meeting. 2014. URL: http://www.acelrx.com/technology/publications/arx-04/2014%20APS%20Optimizing%20PK%20Poster%20Final%204%2022%2014.pdf (дата обращения 26.12.2017).; C. Metz, L. Gobel, M. Gruber, K.H. Hoerauf, K. Taeger. Pharmacokinetics of Human Cerebral Opioid Extraction. A Comparative Study on Sufentanil, Fentanyl, and Alfentanil in a Patient after Severe Head Injury // Anesthesiology. 2000. V. 92. P. 1559-67.; H.S. Minkowitz, D.Leiman, T. Melson, N. Singla, K.P. Di Donato, P.P. Palmer. Sufentanil Sublingual Tablet 30 mcg for the Management of Pain Following Abdominal Surgery: A Randomized, Placebo-Controlled, Phase-3 Study // Pain Practice. 2017. V. 17(7). P. 848-858.; M. Evashenk. Phase 3 Efficacy and Safety Results of the Sufentanil Sublingual Tablet 30 mcg (DSUVIA™). 2017. SOMSA Plenary Session.; H. Minkowitz, N. Singla, T. Melson, D. Leiman, K. Di Donato, P. Palmer. Safety and Efficacy of Sufentanil Sublingual 30mcg Tablets by Surgery Type for the Treatment of Acute Pain Following Outpatient Abdominal Surgery. 2016. SOMSA.; H.S. Minkowitz, N.K. Singla, M.A. Evashenk, S.S. Hwang, Yu-Kun Chiang, L.G. Hamel, P.P. Palmer. Pharmacokinetics of Sublingual Sufentanil Tablets and Efficacy and Safety in the Management of Postoperative Pain // Regional Anesthesia and Pain Medicine. 2013. V. 38 (2). P. 131-139.; Report of the International Narcotics Control Board on the Availability of Internationally Controlled Drugs: Ensuring Adequate Access for Medical and Scientific Purposes. UN. International Narcotics Control Board. 2010. URL: https://www.incb.org/documents/Publications/AnnualReports/AR2010/Supplement-AR10_availability_English.pdf (дата обращения 26.12.2017).; А.В. Соснов, С.С. Голубев, Б.С. Пунке вич, С.В. Садовников, Ф.М. Семченко, В.Н. Тохмахчи, А.А. Соснова. Оценка потребности Российской Федерации в сильнодействующих анальгетиках // Разработка и регистрация лекарственных средств. 2016. № 2(15). C. 202-215.; A.K. Chan, C. W. Cheung, Y.K. Chong. Alpha-2 agonists in acute pain management // Expert Opin Pharmacother. 2010. V. 11(17). P. 2849-68.; J.A. Giovannitti, S.M. Thoms, J.J. Crawford. Alpha-2 Adrenergic Receptor Agonists: A Review of Current Clinical Applications // Anesth Prog. 2015. V. 62(1). P. 31-38.; D.D. Price, D.J. Mayer, J. Mao, F.S. Caruso. NMDA-receptor antagonists and opioid receptor interactions as related to analgesia and tolerance // J Pain Symptom Manage. 2000. V. 19(1). P. 7-11.; K. Subramaniam, B. Subramaniam, R. Steinbrook. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review // Anesth Analg. 2004. V. 99(2). P. 482-95.; D. Jamero, A. Borghol еt al. The Emerging Role of NMDA Antagonists in Pain Management // U.S. Pharmacist. 2001. V. 36(5). P. 4-8. URL: https://www.uspharmacist.com/article/the-emerging-role-of-nmda-antagonists-in-pain-management (дата обращения 02.12.2017).; C.S. Bonnet, A.S. Williams et al. AMPA/ kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis // Ann Rheum Dis. 2015. V. 74(1). P. 242-251.; D.R. Kirkpatrick et al. Transmission pathways and mediators as the basis for clinical pharmacology of pain // Expert Rev Clin Pharmacol. 2016. V. 4. P. 1-25.; A Study to Evaluate the Clinical Efficacy, Safety and Tolerability of ARX-F03 Sublingual Sufentanil/Triazolam Nano-Tab™ in Patients Undergoing an Elective Abdominal Liposuction Procedure // ClinicalTrials. AcelRx Pharmaceuticals, Inc. URL: https://clinicaltrials.gov/show/NCT00894699 (дата обращения 02.12.2017).; D. Perret, Z.D. Luo. Targeting voltagegated calcium channels for neuropathic pain management // Neurotherapeutics. 2009. V. 6(4). P. 679-92.; S. Goyal et al. Comparison of the Effects of Zonisamide, Ethosuximide and Pregabalin in the Chronic Constriction Injury Induced Neuropathic Pain in Rats // Ann Med Health Sci Res. 2015. V. 5(3). P. 189-96.; J.A. Fidler, Y.A. Jamal et al. GABA antagonist, delays return of righting reflex in mice after isoflurane anesthesia but does not significantly alter dendritic spine density // 46th Annu Meet Soc Neurosci. San Diego. 2016. Abst. 343.20.; P. Compton, P. Kehoe, K. Sinha. Gabaрentin improves cold-pressor pain res-ponses in methadone-maintained patients // Drug Alcohol Depend. 2010. V. 109(1-3). P. 213-9.; N. Stoicea, D. Russell, G. Weidner, M. Durda, S.D. Bergese. Opioid-induced hyperalgesia in chronic pain patients and the mitigating effects of gabapentin // Front Pharmacol. 2015. V. 27. P. 96-104.; D.L. Cichewicz. Synergistic interactions between cannabinoid and opioid analgesics // Life Sci. 2004. V. 74(11). P. 1317-1324.; J. Elikkottil, P. Gupta, K. Gupta. The analgesic potential of cannabinoids // J Opioid Manag. 2009. V. 5(6). P. 341-357.; L.R. Gerak, C.P. France. Combined Treatment with Morphine and Δ9- Tetrahydrocannabinol in Rhesus Monkeys: Antinociceptive Tolerance and Withdrawal // Journal of Pharmacology and Experimental Therapeutics. 2016. V. 357(2). P. 357-366.; D.R. Maguire, C.P. France. Interactions between cannabinoid receptor agonists and mu opioid receptor agonists in rhesus monkeys discriminating fentanyl // Eur J Pharmacol. 2016. V. 5(784). P. 199-206.; D.R. Maguire, C.P. France. Impact of efficacy at the μ-opioid receptor on antinociceptive effects of combinations of μ-opioid receptor agonists and cannabinoid receptor agonists // J Pharmacol Exp Ther. 2014. V. 351(2). P. 383-389.; F. Shen, P.R. Tsuruda, J.A. Smith, G.P. Obedencio, W.J. Martin. Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model // PLoS One. 2013. V. 8(9). P. 74891.; M.L. Banks, K.C. Rice, S.S. Negus. Antinociceptive interactions between Mu-opi-oid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy // J Pharmacol Exp Ther. 2010. V. 335(2). P. 497-505.; J.X. Li, W. Koek, K.C. Rice, C.P. France. Effects of direct- and indirect-acting serotonin receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in rhesus monkeys // Neuropsychopharmacology. 2011. V. 36(5). P. 940-949.; K. Di Donato, P.P. Palmer, T.E. Morris, J. Walker, M. Casamayor, M. Hennebert. Intravenous administration of morphine in the emergency room inflicts a substantial economic burden in the EU5. Poster PSY45. ISPOR 19th Annual European Congress. 2016.; S.L. Kane-Gill. The cost of opioid-related adverse drug events // Journal of pain & palliative care pharmacotherapy. 2014. V. 28(3). P. 282-293.; H. Smith. A Comprehensive Review of Rapid-Onset Opioids for Breakthrough Pain // CNS Drugs. 2012. V. 26(6). P. 509-535.; N.M.L. Veldhorst-Janssen, A.A.A. Fiddelers, P.-H.M. van der Kuy, C. Neef, M.A.E. Marcus. A Review of the Clinical Pharmacokinetics of Opioids, Benzodiazepines, and Antimigraine Drugs Delivered Intranasally // Clinical Therapeutics. 2009. V. 31 (12). P. 2954-2987.; Oral ALLOD-2 vs. Its Components & vs. Placebo in the Acute Treatment of Migraine (ANODYNE-1). NCT03061734. 2017. URL: https://clinicaltrials.gov/show/NCT03061734 (дата обращения 10.12.2017).; L. Gorecki, J. Korabecny, K. Musilek, E. Nepovimova, D. Malinak, T. Kucera, R. Dolezal, D. Jun, O. Soukup, K. Kuca. Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016) // Expert Opinion on Therapeutic Patents. 2017. V. 27(9).; А.В. Соснов, М.И. Власов, С.В. Садовников, К.А. Руфанов, Ф.М. Семченко, А.А. Соснова, А.С. Радилов, Е.И. Савельева. Методы обнаружения токсикантов с использованием люминесцентных реагентов // Разработка и регистрация лекарственных средств. 2017. № 4(21). C. 108-125.; W.J. Geldenhuys, A.S. Mohammad, C.E. Adkins, P.R. Lockman. Molecular determinants of blood-brain barrier permeation // Ther. Deliv. 2015. V. 6(7). P. 961-971.; О.И. Рудько, Е.А. Климов, В.В. Соболев, А.В. Соснов, К.А. Руфанов, Ф.М. Семченко. Исследование влияния интраназального введения препарата дексмедетомидин на болевую чувствительность // Разработка и регистрация лекарственных средств. 2017. № 2 (19). C. 236-241.; V.N. Tohmahchi, M.S. Krymchak, A.I. Korovyakovskaya, F.M. Semchenko, A.V. Sosnov. Transdermal therapeutic systems for benzodiazepines // 250th American Chemical Society National Meeting. 2015. Poster.; И.Н. Станьков, В.Б. Кондратьев, И.Д. Деревягина, П.В. Казаков, О.И. Лукашов, О.Т. Морозова, Ф.М. Семченко, А.В. Соснов. Газохроматографическое определение микроколичеств эпибатидина и его биомаркера в плазме крови // Журнал аналитической химии. 2015. Т. 70. № 2. С. 189-195.; А.В. Соснов, С.С. Голубев, Б.С. Пункевич, С.В. Садовников, Е.М. Загребин, И.С. Родина, Ф.М. Семченко, А.А. Соснова. Стандартные образцы контролируемых сильнодействующих компонентов препаратов анальгетиков // Разработка и регистрация лекарственных средств. 2016. № 1(14). C. 216-223.; А.В. Соснов, Б.С. Пункевич, С.В. Садовников, Ф.М. Семченко. Разработка и выпуск стандартных образцов контролируемых биологически активных веществ ограниченного использования // II-я Международная научная конференция «Стандартные образцы в измерениях и технологиях». 2015.; Федеральный закон от 08.01.1998 № 3-ФЗ (ред. от 03.07.2016) «О наркотических средствах и психотропных веществах» (с изм. и доп., вступ. в силу с 01.01.2017). URL: http://www.consultant.ru/document/cons_doc_LAW_17437/ (дата обращения 02.12.2017).; Федеральный закон от 26.06.2008 № 102-ФЗ (ред. от 13.07.2015) «Об обеспечении единства измерений». URL: http://docs.cntd.ru/document/902107146 (дата обращения 14.12.2017).; Е.В. Осинцева. Тенденции и перспективы развития номенклатуры стандартных образцов в РФ // Материалы II-й Международной научной конференции «Стандартные образцы в измерениях и технологиях». 2015.; https://www.pharmjournal.ru/jour/article/view/554

  6. 6
    Academic Journal

    المصدر: Drug development & registration; № 4 (2017); 108-124 ; Разработка и регистрация лекарственных средств; № 4 (2017); 108-124 ; 2658-5049 ; 2305-2066

    وصف الملف: application/pdf

    Relation: https://www.pharmjournal.ru/jour/article/view/505/500; Конвенция о запрещении разработки, производства, накопления и применения химического оружия и его уничтожении. Официальный документ ООН и OPCW. Редакция от 29.07.2005. URL: https://www.opcw.org/fileadmin/OPCW/CWC/CWC_ru.pdf (дата обращения 04.09.2017).; Timeline of Syrian Chemical Weapons Activity, 2012-2017. ACA 2017. URL:https://www.armscontrol.org/factsheets/Timeline-of-Syrian-Chemical-Weapons-Activity (дата обращения 04.09.2017).; E. Dearing, C. Flood. Sampling and analysis relevant to the implementation of the chemical weapons convention. 2015. OPCW Laboratory. - Rijswijk, The Netherlands: OPCW Laboratory. 2015. URL: https://www.opcw.org/fileadmin/OPCW/Science_Technology/Sampling_and_Analysis_-_LAB.pdf (дата обращения 04.09.2017).; N. Grigoriu, G. Epure, R. Ginghina, D. Mosteanu. An overview of the opcw’s programme for biomedical samples analysis // International conference knowledge-based organization. Conference proceedings. 2015. V. XXI, № 3. URL:https://www.degruyter.com/downloadpdf/j/kbo.2015.21.issue -3/kbo-2015-0138/kbo-2015-0138.pdf (дата обращения 04.09.2017).; OPCW AT 20. 20th anniversary of the entry into force of the Chemical Weapons Convention. URL: https://20years.opcw.org/ (дата обращения 09.06.2017).; A.T. Tu. Overview of Sarin Terrorist Attacks in Japan // ACS Symposium Series. 1999. V. 745. P. 304-317.; Chemical terrorism: horrors in Tokyo subway and Matsumoto City / Ed. by A.T. Tu. - Fort Collins: Alaken, 2002. 240 p.; OPCW Fact-Finding Mission Reports. Syria and the OPCW. OPCW. URL: https://www.opcw.org/special-sections/syria/fact-finding-mission-reports/ (дата обращения 04.09.2017).; OPCW Director-General Shares Incontrovertible Laboratory Results Concluding Exposure to Sarin. OPCW. 19.04.2017. URL: https://www.opcw.org/news/article/opcw-director-general-shares-incontrovertible-laboratory-results-concluding-exposure-to-sarin/ (дата обращения 04.09.2017).; A.T. Tu. Toxicological and chemical aspects of sarin terrorism in japan in 1994 and 1995 // Toxin Reviews. 2007. V. 26. P. 231-274.; R.K. Mishra, L.J. Hubble, A. Martín et. al. Wearable Flexible and Stretchable Glove Biosensor for On-Site Detection of Organophosphorus Chemical Threats // ACS Sens. 2017. V. 2(4). P. 553-561.; Handbook of toxicology of chemical warfare agents. 2nd ed. by R.C. Gupta. - Elsevier. 2015. 1184 p.; J. Bajgar. Laboratory Diagnosis of Organophosphates/Nerve Agent Poisoning // Klin. Biochem. Metab. 2005. V. 13 (34). № 1. P. 40-47.; Chemical Warfare Agents. Chemistry, Pharmacology, Toxicology, and Therapeutics / Ed. by J.A. Romano, Jr. - NY: CRC Press. Taylor & Francis Group, 2008. 723 p.; Y.J. Jang, K. Kim, O.G. Tsay, D.A. Atwood, D.G. Churchill. Destruction and Detection of Chemical Warfare Agents // Chem. Rev. 2015. V. 115(24). P. 1-76.; E. Halámek, Z. Kobliha. Potenciální bojové chemické látky // Chem. Listy. 2011. V. 105. P. 323-333.; M.D. Crenshaw. Methylphosphonofluoridic Acid A Thermal Degradation Product Of Some Nerve Agents. Report. 2002. Battelle Memorial Institute Columbus. Ohio. URL: www.dtic.mil/gettr-doc/pdf?AD=ADA436023 (дата обращения 04.09.2017).; T.E. McKone, B.M. Huey, E. Downing, L.M. Duffy. Editors Strategies to Protect the Health of Deployed U.S. Forces. Detecting, Characterizing, and Documenting Exposures. - Washington, D.C.: National academy press, 2000. 272 p.; Sarin // Wikipedia. URL: https://en.wikipedia.org/wiki/Sarin (дата обращения 04.09.2017).; Sarin. NIOSH emergency response card. URL: http://cs.erplan.net/WMD/ChemFiles/Links/ChemicalAgents/Niosh/SarinNiosh.htm (дата обращения 04.09.2017).; Note by the technical secretariat. Status update of the opcw fact-finding mission in Syria regarding a reported incident in Khan Shaykhun, 4 April 2017. OPCW Technical Secretariat. S/1497/2017. 12.04.2017.; Note by the technical secretariat report of the OPCW Fact-finding mission in Syria regarding an alleged incident in Khan Shaykhun, Syrian Arab Republic. April 2017. OPCW Technical Secretariat. S/1510/2017. 29.06.2017.; R.W. Baier, S.W. Weller. Catalytic and Thermal Decomposition of Isopropyl Methyl Fluorophosphonate // I&EC. Proc. Des. Develop. 1967. V. 6. P. 380-385.; L.L. Swaim, R.C. Johnson, Y. Zhou, C. Sandlin, J.R. Barr. Quantification of Organophosphorus Nerve Agent Metabolites Using a Reduced-Volume, High-Throughput Sample Processing Format and Liquid Chromatography- Tandem Mass Spectrometry // Journal of Analytical Toxicology. 2008. V. 32(9). P. 774-777.; E.I. Hamelin, N.D. Schulze, R.L. Shaner, R.M. Coleman, R.J. Lawrence, B.S. Crow, E.M. Jakubowski, R.C. Johnson. Quantitation of five organophosphorus nerve agent metabolites in serum using hydrophilic interaction liquid chromatography and tandem mass spectrometry // Anal Bioanal Chem. 2014. V. 406(21). P. 5195-5202.; T. Postol. Khan Sheikhoun, Syria: The Nerve Agent Attack that Did Not Occur. Analysis of the Times and Locations of Critical Events in the Alleged Nerve Agent Attack at 7 AM on April 4, 2017 in Khan Sheikhoun, Syria. Global Research. 19.04.2017. URL: http://www.globalresearch.ca/khan-sheikhoun-syria-the-nerve-agent-attack-that-did-not-occur/5585818; http://www. ibtimes.co.uk /mit-expert-claims-latest-chemical.-weapons-attack-syria-was-staged-1617267 (дата обращения 04.09.2017).; H.J. O’Neill, K.L. Brubaker, J.F. Schneider, L.F. Sytsma, T.A. Kimmell. Development of an analytical methodology for sarin (GB) and soman (GD) in various militaryrelated wastes // J Chromatogr A. 2002. V. 12(962(1-2)). P. 183-95.; M. Hamel, J. Hamoniaux, L. Rocha, S. Normand. Ppb detection of Sarin surrogate in liquid solutions // Proc. of SPIE. 2013.V. 8710. USACHPPM Technical Guide 230: Chemical Exposure Guidelines for Deployed Military Personnel. 2006. URL: http://chppm (дата обращения 04.09.2017).; R.A. Potyrailo, C. Surman, N. Nagraj et. al. Materials and Transducers Toward Selective Wireless Gas. Sensing // Chem. Rev. 2011. V. 111. P. 7315-7354.; Н.Г. Британов. Гигиенические аспекты перепрофилирования или ликвидации объектов по хранению и уничтожению химического оружия: дисс. д.м.н. - Волгоград. 2014. URL: http://www.volgmed.ru/uploads/dsovet/thesis/6-605-britanov_nikolaj_grigorevich.pdf (дата обращения 04.09.2017).; P. Khan, D. Idrees, M.A. Moxley. Luminol-Based Chemiluminescent Signals: Clinical and Non-clinical Application and Future Uses // Biochem Biotechnol. 2014. V. 173(2). P. 333-355.; Y.S. Suh, M. Kamruzzaman, А.-М. Alam. Chemiluminescence determination of moxifloxacin in pharmaceutical and biological samples based on its enhancing effect of the luminol-ferricyanide system using a microfluidic chip // Luminescence. 2014. V. 29(3). P. 248-253.; M.J. Corey. Coupled Bioluminescent Assays: Methods, Evaluations, and Applications. - NY: John Wiley & Sons, 2008. 308 p.; S. Ripp, P. Jegier, C. Johnson, S. Moser, S. Islam, G. Sayler. Bioluminescent bioreporter assays for targeted detection of chemical and biological agents // Proc. of SPIE. 2008. V. 6945. URL: https://www.researchgate.net/profile/Steven_Ripp/publication/252199541_Bioluminescent_bioreporter_assays_for_targeted_detection_of_chemical_and_biological_agents/links/00b4953722abfcd2fb000000/Bioluminescent-bioreporter-assays-for-targeted-detection-of-chemical-and-biological-agents.pdf?origin=publication_detail (дата обращения 04.09.2017).; S.L. Fox, K.A. Daum, C.J. Miller, M.M. Cortez. Emergency First Responders’ Experience With Colorimetric Detection Methods. Report. U.S. Department of Homeland Security. 2007. URL: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.517.2914&rep=rep1&type=pdf (дата обращения 04.09.2017).; M.J. Kangas, R.M. Burksb, J. Atwatera, R.M. Lukowicza, P. Williamsc, A.E. Holmes. Colorimetric Sensor Arrays for the Detection and Identification of Chemical Weapons and Explosives // Critical reviews in analytical chemistry. 2017. V. 47. № 2. P. 138-153.; P. Emanuel. Biological & Chemical Sensors for Emerging Applications. Opening keynote presentation. Biological & Chemical Sensors for Emerging Applications. December 6-7, 2016.; А.В. Соснов, Б.С. Пункевич, С.В. Садовников, Ф.М. Семченко. Разработка и выпуск стандартных образцов контролируемых биологически активных веществ ограниченного использования // Доклад на II-й Международной научной конференции «Стандартные образцы в измерениях и технологиях». Екатеринбург, 2015. URL: https://www.researchgate.net/publication/315457651_Development_and_production_of_reference_standards_of_controlled_high-potent_biologically_active_substances (дата обращения 04.09.2017).; Pocket-sized micro spectrometer URL: https://www.consumerphysics.com/business/technology/ (дата обращения 04.09.2017).; S.-W. Zhang, T. Swager. Fluorescent Detection of Chemical Warfare Agents: Functional Group Specific Ratiometric Chemosensors // J. Am. Chem. Soc. 2003. V. 125. P. 3420-3421.; Tae-Il, K. Shubhra, B. Maity, J. Bouffard, Y. Kim. Molecular Rotors for the Detection of Chemical Warfare Agent Simulants // Anal. Chem. 2016. V. 88(18). P. 9259-9263.; J.R. Schwierking, L.W. Menzel, E.R. Menzel. Organophosphate Nerve Agent Detection with Europium Complexes // The Scientific World Journal. 2004. V. 4. P. 948-955.; J.C. Bunzli, C. Piguet. Lanthanide-containing molecular and supramolecular polymetallic functional assemblies // Chem. Rev. 2002. V. 102 (6). P. 1897-1928.; G.H. Dennison, M.R. Sambrook, M.R. Johnston. VX and VG chemical warfare agents bidentate complexation with lanthanide ions // Chem. Commun. 2014. V. 50. P. 195-197.; J. Como. A Europium Complex Doped Silica Sol-Gel Thin Film for Detection of Trace Organophosphate Vapor: PhD Dissertation. - Texas: Tech University, 2010. URL: https://ttu-ir.tdl.org/ttu-ir/bitstream/handle/2346/ETD-TTU-2010-12-1123/COMO-DISSERTATION.pdf?sequence=1 (дата обращения 04.09.2017).; S. Quici, G. Marzanni, M. Cavazzini et al. Highly Luminescent Eu3+ and Tb3+ Macrocyclic Complexes Bearing an Appended Phenanthroline Chromophore // Inorganic Chemistry. 2002. V. 41(10). P. 2777-2784.; D. Knapton, M. Burnworth, S.J. Rowan, C. Weder, Fluorescent Organometallic Sensors for the Detection of Chemical- Warfare-Agent Mimics // Angew. Chem. Int. Ed. 2006. V. 45. P. 5825-5829.; M. Burnworth, S.J. Rowan, C. Weder. Fluorescent Sensors for the Detection of Chemical Warfare Agents // Chem. Eur. J. 2007. V. 13. P. 7828-7836.; E.R. Menzel, L.W. Menzel, J.R. Schwierking. Rapid fluorophosphate nerve agent detection with lanthanides // Talanta, 2005. V. 67. P. 383-387.; Patent WO 2006076430 A1. Nerve agent detection method and device / E.R. Menzel; Texas Tech University. 2005.; S. Zhao, L. Zhang, W. Li, L. Li. Preparation and Fluorescent Property of Eu(TTA)3Phen Incorporated in Polycarbonate Resin // Polymer Journal. 2006. V. 38(6). P. 523-526.; H.-X. Zhang, R.-B. Wei, C.-Z. Chen, X.-L. Tuo, X.-G. Wang. A novel fluorescent epoxy resin for organophosphate pesticide detection // Chinese Chemical Letters. 2015. V. 26. P. 39-42.; K. Kanagaraj, A. Affrose, S. Sivakolunthu, K. Pitchumani. Highly selective fluorescent sensing of fenitrothion using per-6-amino-beta-cyclodextrin:Eu(III) complex // Biosensors and Bioelectronics. 2012. V. 35. P. 452-455.; J.W. Boyd, G.P. Cobb, G.E. Southard, G.M. Murray. Development of Molecularly Imprinted Polymer Sensors for Chemical Warfare Agents // Johns Hopkins Apl. Technical Digest. 2004. V. 25(1). P. 44-49.; G.M. Murray. Molecularly imprinted polymer solution anion sensor. 2003. WO 2003034043 A2 The Johns Hopkins University.; A. Verma, G.M. Murray. A Path to Soluble Molecularly Imprinted Polymers // J. Funct. Biomater. 2012. V. 3. P. 1-22.; A.L. Jenkins, O. Manuel Uy, G.M. Murray. Polymer-Based Lanthanide Luminescent Sensor for Detection of the Hydrolysis Product of the Nerve Agent Soman in Water // Anal. Chem. 1999. V. 71. P. 373-378.; Patent US 20120164027 A1. Polymer Based Lanthanide Luminescent Sensors for the Detection of Organophosphorus Compounds / G.M. Murray, O.M. Uy, A.L. Jenkins. 2012.; S.L. Bartelt-Hunt, D.R.U. Knappe, M.A. Barlaz. A Review of Chemical Warfare Agent Simulants for the Study of Environmental Behavior // Critical Reviews in Environmental Science and Technology. 2008. V. 38(2). P. 112-136.; МУК 4.1.011-2010. Методические указания по методам контроля. Методика выполнения измерений массовой концентрации зомана в пробах водных объектов хозяйственно-питьевого и культурно-бытового водопользования методом газовой хроматографии (утв. заместителем руководителя ФМБА России 18.05.2010).; МУК 4.1.66-2004. Методика измерений массовой концентрации Vx в воде водных объектов хозяйственно-питьевого и культурно-бытового водо-пользования биохимическим методом. ФГУП «УНИИМ» - ГНМЦ. 2004. Свидетельство №224.01.17.209/2004.; S.V. Sadovnikov, A.V. Sosnov, E.A. Fokin et. al. Investigation of Antiatherosclerotic Properties of Selective BuChE Inhibitors // XIVth International Conference on Phosphorus Chemistry (ICPC-14, Cincinnati, USA). 1998. P. 226.; Патент РФ 2041878. N,N-диалкил-амидофтор-о-(транс-2-замещенные циклоалкил)фосфаты / С.В. Садовников, А.В. Соснов, Е.А. Фокин и др. - Заявл. 30.07.93; опубл. 20.08.95. URL: http://www.freepatent.ru/patents/2041878.; Патент РФ 2102398. N-(2-диизо-пропилоксифосфорилтиоэтил)-n-(замещенные бензил)-n,n-диалкиламмоний, пиперидиний или морфолиний галогениды / М.А. Кочетков, С.В. Садовников, А.В. Соснов, Е.А. Фокин и др. - Заявл. 11.11.96; опубл. 20.01.98. URL: http://www.freepatent.ru/patents/2102398 (дата обращения 04.09.2017).; K.A. Anikienko, S.V. Sadovnikov, A.V. Sosnov, E.A. Fokin et. al. Selective butyrylcholinesterase inhibitors among dialkylphosphoramidofluoridates // Phosphorus, Sulfur and Silicon and the Related Elements. 2006. V. 130(1). Р. 115-129.; K.A. Anikienko, S.V. Sadovnikov, A.V. Sosnov et. al. Selective Butyrylcholinesterase Inhibitors as Model Substances // The 7th International Symposium on Protection against Chemical and Biological Warfare Agents. - Stockholm, Sweden. 2001.; Chemical Warfare Agents: Toxicology and Treatment / Ed. By Timothy T. Marrs. - NY: John Wiley & Sons, 2007. 750 p.; I.N. Stan’kov, I.D. Derevyagina, V.B. Kondrat’ev, V.B. Sitnikov, S.V. Sadovnikov, S.N. Mylova. Gas-Chromatographic Determination of Trace S-[2-(N,N-Diethylamino)ethyl]Methylphos-phonothioic Acid in Water // Journal of Analytical Chemistry. 2008. V. 63(7). P. 668-673.; S.V. Sadovnikov, I.N. Stan’kov, I.D. Derevyagina, A.V. Sosnov. Development of samples preparation scheme for detection of S-[2-(N,N-diethylamino)ethyl] methylthiophosphonate trace amounts in a water environment // 33rd AMOP Technical Seminar on Environmental Contamination and Response. Canada. 2010.; M. Pohankaa, J. Zdarova Karasovab, K. Kucaa, J. Pikulac, O. Holasb, J. Korabecnyb, J. Cabal. Colorimetric dipstick for assay of organophosphate pesticides and nerve agents represented by paraoxon, sarin and VX // Talanta. 2010. V. 81. P. 621-624.; Chemical and Biological Terrorism: Research and Development to Improve Civilian Medical Response / Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents. - Washington (DC): National Academies Press, 1999. 304 p.; B. Díaz de Gren et. al. Fluorescent Discrimination between Traces of Chemical Warfare Agents and Their Mimics // J. Am. Chem. Soc. 2014. V. 136. P. 4125-4128.; Y. Liu, M. Bonizzoni. A Supramolecular Sensing Array for Qualitative and Quantitative Analysis of Organophosphates in Water // J. Am. Chem. Soc. 2014. V. 136. P. 14223-14229.; E. Climent, M. Biyikal, K. Gawlitza, T. Dropa, M. Urban, A.M. Costero, R. Martnez, K. Rurack. A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials // Chem. Eur. J. 2016. V. 22. P. 1-6.; E.T. Gainullina, K.V. Kondratyev, S.B. Ryzhikov, V.F. Taranchenko. Fluorescent Method for Evaluation of Cholinesterase Inhibitors // Bulletin of Experimental Biology and Medicine. 2006. V. 142(6). P. 751-752.; S. Royo, R. Martınez-Manez et. al. Chromogenic and fluorogenic reagents for chemical warfare nerve agents’ detection // Chem. Commun. 2007. V. 46 P. 4839-4847.; G.E. Southard, K.A. Van Houten et. al. Luminescent sensing of organophosphates using europium(III) containing imprinted polymers prepared by RAFT polymerization // Anal Chim Acta. 2007. V. 9 (581/2). P. 202-207.; R. Shunmugam, G.N. Tew. Terpyridine-Lanthanide Complexes Respond to Fluorophosphate Containing Nerve Gas G-Agent Surrogates // Chem. Eur. J. 2008. V. 14. P. 5409-5412.; R. Sferopoulos. A Review of Chemical Warfare Agent (CWA) Detector Technologies and Commercial-Off-The-Shelf Items. Human Protection and Performance Division DSTO. Defence Science and Technology Organisation. 2009.; A.A. Fatah, R.D. Arcilesi, J.C. Peterson, C.H. Lattin, C.Y. Wells, J.A. McClintock. Guide for the Selection of Chemical Detection Equipment for Emergency First Responders. 3rd еdition. Office of Law Enforcement Standards. National Institute of Standards and Technology. 2007.; B.M. Gandhi. Chemical Detectors in Defence. A Guide Book. - NeoBioMed Services. 2017.; МУК 4.1.012-2010. Методические указания по методам контроля. Методика выполнения измерений массовой концентрации зарина в пробах водных объектов хозяйственно-питьевого и культурно-бытового водопользования методом газовой хроматографии (утв. заместителем руководителя ФМБА России 18.05.2010).; I.A. Rodina, A.V. Brauna, I.A. Anan’eva, O.A. Shpiguna, E.I. Savel’eva, I.V. Rybal’chenko, S.L. Bolotov, G.M. Rodchenkov. Detection of nerve agent markers by liquid chromatography-mass spectrometry // Journal of Analytical Chemistry. 2011. V. 66. № 14. P. 1417-1422.; J.S. Tsang, A.A. Neverov, R.S. Brown. Billion-fold Acceleration of the Methanolysis of Paraoxon Promoted by La(OTf )3 in Methanol // J. Am. Chem. Soc. 2003. V. 125(25). P. 7602-7607.; T. Andrea, A.A. Neverov, R.S. Brown. Efficient Methanolytic Cleavage of Phosphate, Phosphonate, and Phosphonothioate Esters Promoted by Solid Supported Lanthanide Ions // Ind. Eng. Chem. Res. 2010. V. 49(15). P 7027-7033.; B.B. Dhar, D.R. Edwards, R.S. Brown. A Study of the Kinetics of La3+-Promoted Methanolysis of S-Aryl Methylphosphonothioates: Possible Methodology for Decontamination of EA 2192, the Toxic Byproduct of VX Hydrolysis // Inorg. Chem. 2011. V. 50. P. 3071-3077.; Л.К. Густылева, Н.С. Хлебникова, Е.И. Савельева, А.С. Радилов. Анализ химического состава продуктов разложения российского вещества vx в условиях каталитического метанализа // Аналитика и контроль. 2013. Т. 17(2). С. 190-195.; V. Blinov, K. Volchek, W. Kuang, C.E. Brown, A. Bhalerao. Two-Stage Decontamination of Organophosphorus Compounds on Sensitive Equipment Materials // Ind. Eng. Chem. Res. 2013. V. 52. P. 1405-1413.; V. Blinov, K. Volchek, W. Kuang, A. Bhalerao, C.E. Brown. Decontamination of Paraoxon and Parathion on Sensitive Equipment Materials by Catalytic Methanolysis // Ind. Eng. Chem. Res. 2014. V. 53. P. 13856-13861.; Patent US 8722956 B2. Kit for decomposing organophosphorus compounds / R.S. Brown, A.A. Neverov, J.S.W. Tsang. - 2014.; D.R. Edwards, R.S. Brown. Development of metal-ion containing catalysts for the decomposition of phosphorothioate esters // Biochimica et Biophysica Acta. 2013. V. 1834. P. 433-442.; ИПП-11. URL: https://ru.wikipedia.org/wiki/%D0%98%D0%9F%D0%9F-11 (дата обращения 04.09.2017).; Патент РФ № 2050849. Средство для лечения гнойных ран / В.Р. Рембовский, А.Б. Слободской, В.И. Сериков и др. 1995. URL: http://ru-patent.info/20/50-54/2050849.html (дата обращения 04.09.2017).; Patent WO 2007027118 A1. Dermatological composition / V.S. Polyakov, A.P. Gorshkov, N.A. Vorotyagina. - 2005.; G.H. Dennison, C.G. Bochet, C. Curty et. аl. The foundations for selective, sensitive and rapid next generation detection of v-series chemical warfare agents with trivalent lanthanide based systems // 12th International Symposium on Protection against Chemical and Biological Warfare Agents. Stockholm, Sweden. 2016.; A.W. Fountain III. Trends and future challenges for the cbrne detection. Plenary lecture Detection and On-Site Analysis // 12th International Symposium on Protection against Chemical and Biological Warfare Agents. Stockholm, Sweden. 2016.; Report of the scientific advisory board’s workshop on emerging technologies. OPCW Twenty-Sixth Session. OPCW. 2017.; https://www.pharmjournal.ru/jour/article/view/505

  7. 7
    Academic Journal

    المصدر: Drug development & registration; № 2 (2017); 176-187 ; Разработка и регистрация лекарственных средств; № 2 (2017); 176-187 ; 2658-5049 ; 2305-2066

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    Relation: https://www.pharmjournal.ru/jour/article/view/427/422; Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research / Institute of Medicine (US) Committee on Advancing Pain Research, Care, and Education. - Washington (DC): National Academies Press (US), 2011. 364 p.; Общие проблемы хронической и патологической боли. Курс образовательных статей по проблемам диагностики и лечения хронической боли. URL: https://www.painstudy.ru/education/index.php (дата обращения 11.02.2017).; H. Breivik, E. Eisenberg, T. O’Brien. The individual and societal burden of chronic pain in Europe: the case for strategic prioritisation and action to improve knowledge and availabilit y of appropriate care // BMC Public Health. 2013. V. 13. P. 1229-1243.; Болевой синдром. Клинические рекомендации. Общероссийская общественная организация «Ассоциация врачей общей практики (семейных врачей) Российской Федерации». - Москва - Санкт-Петербург - Ростов-на-Дону. 2014. 27 c.; С.С. Павленко. Состояние и проблемы эпидемиологических исследований болевых синдромов // Боль. 2006. № 4. C. 2-7.; А.Б. Данилов. Новые подходы в лечении пациентов с хронической болью// Лечащий врач. URL: http://www.lvrach.ru/2009/04/7634652/ (дата обращения 13.04.2017).; Steady Growth in Drug and Device Markets for Pain Management. Market Research Report // BCC Research LLC. 2015. № 8. Р. 28-36.; Pain Relieving Drugs Market Forecast 2017-2027. ReportBuyer Ltd. United Kingdom. Dec. 2016.; E. George, I. Elman. Pain in an era of armed conflicts: Prevention and treatment for warfighters and civilian casualties // Prog. Neurobiol. 2016. № 141. P. 25-44.; C. Giannou. M. Baldan. War Surgery. Working with limited resources in armed conflict and other situations of violence // International Committee of the Red Cross. 2010. V. 1. 283 р.; U. Friedman. Global Conflicts to Watch in 2017 / The Council on Foreign Relations (CFR). December 2016.; А.В. Соснов, С.С. Голубев, Б.С. Пункевич, С.В. Садовников, Ф.М. Семченко, В.Н. Тохмахчи, А.А. Соснова. Оценка потребности российской федерации в сильнодействующих анальгетиках // Разработка и регистрация лекарственных средств. 2016. № 2 (15). C. 202-215.; Я.В. Власов, Е.В. Синеок, Н.П. Дронов. Анализ основных проблем доступности оказания паллиативной медицинской помощи онкобольным // Ремедиум. 21.09.2016. URL: http://www.remedium.ru/health/detail.php?ID=69753 (дата обращения 11.02.2017); Наличие психоактивных средств, находящихся под международным контролем: обеспечение надлежащего доступа для медицинских и научных целей // Доклад OOH / Международный комитет по контролю над наркотиками. - Нью-Йорк, ООН. 2011. URL: http://www.un.org/ru/development/surveys (дата обращения 11.02.2017); А.Д. Каприн. Фармакотерапия хронического болевого синдрома у взрослых пациентов при оказании паллиативной медицинской помощи в стационарных и амбулаторно-поликлинических условиях. Методические рекомендации / ФГБУ «ФМИЦ им. П.А. Герцена». - М.: Министерство здравоохранения РФ, 2015.; А.Д. Каприн, Р.Г. Абузарова. Фармакотерапия онкологической боли в России. Реальность и перспективы // Материалы Международного медицинского конгресса «Паллиативная медицина в здравоохранении Российской Федерации и стран СНГ». Москва. 2014. URL: www.palliamed.ru/files/download/file335.html (дата обращения 15.01.2017).; А.В. Соснов, С.В. Садовников, Ф.М. Семченко, К.А. Руфанов, В.Н. Тохмахчи, А.А. Соснова, И.А. Тюрин. Сильнодействующие ненаркотические анальгетики как направление развития фармацевтики // Разработка и регистрация лекарственных средств. 2016. № 1 (14). С. 196-207.; R. Sheu, D. Lussier, A. Rosenblum, et al. Prevalence and characteristics of chronic pain in patients admitted to an outpatient drug and alcohol treatment program // Pain Med. 2008. V. 9 (7). P. 911-917.; M. Egli, G.F. Koob, S. Edwards. Alcohol dependence as a chronic pain disorder // Neurosci. Biobehav. Rev. 2012. V. 36 (10). P. 2179-2192.; A.V. Apkarian, V. Neugebauer, G. Koob, et al. Neural mechanisms of pain and alcohol dependence // Pharmacol Biochem Behav. 2013 V. 112. P. 34-41.; J.L. Riley, C. King. Self-report of alcohol use for pain in a multi-ethnic community sample // J Pain. 2009. V. 10 (9). P. 944-952.; Horn-Hofmann et al. The effect of nonrecurring alcohol administration on pain perception in humans: a systematic review // Journal of Pain Research. 2015. V. 8. P. 175-187.; Повышение доступности наркотических и психотропных средств для использования в медицинских целях. Распоряжение Правительства РФ № 1403-р от 01.07.2016.; A.L. Harvey. Toxins and drug discovery. Review // Toxicon. 2014. V. 92. P. 193-200.; Обезболивание при раке. - Женева. ВОЗ. 1998. 75 с. URL: http://apps.who.int/iris/bitstream/10665/141317/1/5225017924.pdf (дата обращения 11.02.2017); A. Caraceni at al. Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC // Lancet Oncol. 2012. V. 13 (2). P. 58-68.; P. Beaulieu, D. Lussier, F. Porreca, A. Dickenson. Pharmacology of Pain. - Seattle: IASP Press, 2010. 638 p.; A.S. Reddy, S. Zhang. Polypharmacology: drug discovery for the future // Expert Rev Clin Pharmacol. 2013 V. 6 (1). P. 43-47.; M. Duerden, T. Avery, R. Payne. Polypharmacy and medicines optimisation. - London. The King’s Fund. 2013. 56 р. URL: https://www.kingsfund.org.uk/sites/files/kf/field/field_publication_file/polypharmacy-and-medicines-optimisation-kingsfund-nov13.pdf (дата обращения 15.04.2017).; K. Barnett, S.W. Mercer, M. Norbury, G. Watt. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study // The Lancet. (2012). V. 380. P. 37-43.; C.E. Argoff, D.I. Silvershnein. A Comparison of Long- and Short-Acting Opioids for the Treatment of Chronic Noncancer Pain: Tailoring Therapy to Meet Patient Needs // Mayo Clin Proc. 2009. V. 84 (7). P. 602-612.; А.В. Соснов, С.С. Голубев, Б.С. Пункевич, С.В. Садовников, Е.М. Загребин, И.С. Родина, Ф.М. Семченко, А.А. Соснова. Стандартные образцы контролируемых сильнодействующих компонентов препаратов анальгетиков // Разработка и регистрация лекарственных средств. 2016. № 1 (14). C. 216-223.; В.А. Семенченя, О.М. Конопацкова, Е.А. Валах. Некоторые аспекты медикаментозного лечения хронической боли онкологического генеза: Методические рекомендации для врачей. - Саратов. 2014. 25 c. 2017 № 2 (19) www.pharmjournal.ru; P. Vergne-Salle. Лестница обезболивания ВОЗ: подходит ли она при боли в суставах? От НПВП к опиоидам // IASP. 2016. Fast sheet № 18.; М.Л. Кукушкин. Этиопатогенетические принципы лечения хронической боли // Лечащий Врач. 2008. № 4(8). URL: https://www.lvrach.ru/2008/04/5002175/ (дата обращения 15.04.2017).; T.T. Kararli, K. Sedo, J. Bossart. Fixed-Dose Combination Products. Review // Drug Development & Delivery. 2014. V. 5. URL: http://www.drug-dev.com/Main/Back-Issues/FIXEDDOSE-COM-BINATIONS-FixedDose-Combination-Produ-661.aspx#sthash.HL7Nq3sB.dpuf (дата обращения 11.02.2017); Thomson Reuters Integrity. URL: http://ip-science.thomsonreuters.com/pharma/integrity_whatsnew/ (дата обращения 07.02.2017).; J. Demeules, V. Rollason, V. Piguet, P. Dayer. Clinical pharmacology and rationale of analgesic combinations // European Journal of Anaesthesiology 2003. V. 20 (28). P. 7-12; R.B. Raffa. Analgesic combinations // J Pain. 2010. V. 11(8). P 701-709.; I. Gilron, T.S. Jensen, A.H. Dickenson. Combination pharmacotherapy for management of chronic pain: from bench to bedside // Lancet Neurol 2013. V. 12. P. 1084-95; (A) List of Narcotic analgesic combinations. URL: https://www.drugs.com/drug-class/narcotic-analgesic-combinations.html (дата обращения 07.02.2017). (B) Analgesics, Opioid Combos. URL: http://reference.medscape.com/drugs/analgesics-opioid-combos (дата обращения 07.02.2017).; A. Gatti, E. Sabato. Oxycodone/paracetamol: a low-dose synergic combination useful in different types of pain // Clin Drug Investig. 2010. V. 30 (2). P. 3-14.; J.V. Pergolizzi (Jr.), M. van de Laar, R. Langford, H.-U. Mellinghoff. Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain // Journal of Pain Research. 2012. V. 5. P. 327-346.; R.B. Raffa, J.V. Pergolizzi, D.J. Segarnick, R.J. Tallarida. Oxycodone combinations for pain relief // Drugs Today (Barc). 2010. V. 46(6). P. 379-398.; J. Moore et al. Dexketoprofen/tramadol: randomised double-blind trial and confirmation of empirical theory of combination analgesics in acute pain // The Journal of Headache and Pain. 2015. V. 16. P. 60.; P. Palmer. Compositions and methods for mild sedation, anxiolysis and analgesia in the procedural setting. EP2488156 A1. Acelrx Pharmaceuticals, Inc. 2012. URL: https://clinicaltrials.gov/ct2/show/study/NCT00894699 (дата обращения 20.03.2017).; N. Zeynep, I. Akcaboy, Y. Erkan, I. Akcaboy, et al. Spinal anesthesia with lowdose bupivacaine-fentanyl combination: a good alternative for day case transurethral resection of prostate surgery in geriatric patients // Rev. Bras. Anestesiol. 2012. V. 62 (6). P. 753-761.; D.L. Cichewicz. Synergistic interactions between cannabinoid and opioid analgesics // Life Sci. 2004. V. 74(11). P. 1317-1324.; J. Elikkottil, P. Gupta, K. Gupta. The analgesic potential of cannabinoids // J Opioid Manag. 2009. V. 5(6). P. 341-357.; L.R. Gerak, C.P. France. Combined Treatment with Morphine and Δ9-Tetrahydrocannabinol in Rhesus Monkeys: Antinociceptive Tolerance and Withdrawal // Journal of Pharmacology and Experimental Therapeutics. 2016. V. 357 (2). P. 357-366.; D.R. Maguire, C.P. France. Interactions between cannabinoid receptor agonists and mu opioid receptor agonists in rhesus monkeys discriminating fentanyl // Eur J Pharmacol. 2016. V. 5 (784). P. 199-206.; Sebastiano Mercadante. Opioid combination: rationale and possible clinical applications // Ann Palliat Med. 2013. V 2(4). P. 189-196.; P.-P. Yang, G.-C. Yeh, E.Y.-K. Huang, P.-Y. Law, H.H. Loh, P.-L. Tao. Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice // Journal of Biomedical Science. 2015. V. 22. P. 81.; C. Gharibo. Managing Chronic Moderate to Severe Pain-EMBEDA® (Morphine Sulfate and Naltrexone Hydrochloride) Extended Release Capsules for Oral Use // US Neurology. 2010. V. 6(1). P. 18-22.; L.R. Webster. Oxytrex: an oxycodone and ultra-low-dose naltrexone formulation // Expert Opin Investig Drugs. 2007. V. 16(8). P. 1277-83.; TALWIN Nx. NDA 018733/S-015. FDA Reference ID:2909136. URL: http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018733s015lbl.pdf (дата обращения 11.02.2017); X. Wang, Y. Zhang, et al. Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4 // Br. J. Pharmacol. 2016. V. 173(5). P. 856.; V. Fernández-Dueñas, R. Poveda, et al. Fentanyl-trazodone-paracetamol triple drug combination: multimodal analgesia in a mouse model of visceral pain // Pharmacol Biochem Behav. 2011. V. 98(3). P. 331-336.; E. Schachtel, S. Daniels, et al. Results from using the nausea intensity scale: The severity of nausea is significantly reduced by CL-108 compared with a standard hydrocodone/acetaminophen analgesic when used to treat moderateto-severe pain // 16th World Congr Pain. Yokohama. September 26-30. 2016.; B. Schachte, et al. Clinically meaningful pain relief in patients with moderate to severe acute pain treated with CL-108 // 16th World Congr Pain. Yokohama. 2016.; K. Newman, J. Carsi, S. Han. Analgesic efficacy and safety of oxycodone 5 mg/ ibuprofen 400 mg compared with oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7,5 mg/acetaminophen 500 mg in the dental and orthopedic pain models // 25th Annu Sci Meet. Am Pain Soc. San Antonio. 2006.; J. Mao, M.S. Gold, M. Backonja. Combination Drug Therapy for Chronic Pain: A Call for More. Clinical Studies // J Pain. 2011. V. 12(2). P. 157-166.; A.A. Weinbroum at al. The role of dextromethorphan in pain control // Canadian Journal of Anaesthesia. 2000. V. 47(6). P.585-96.; Постановление Правительства РФ № 681 от 30 июня 1998 г. «Об утверждении перечня наркотических средств, психотропных веществ и их прекурсоров, подлежащих контролю в Российской Федерации» (с изменениями и дополнениями). URL: http://base.garant.ru/12112176/#ixzz4YBIlOJqX (дата обращения 15.03.2017).; V. Fernández-Dueñas, R. Poveda, S. Sánchez, F. Ciruela. Synergistic interaction between fentanyl and a tramadol: paracetamol combination on the inhibition of nociception in mice // J Pharmacol Sci. 2012. V. 118(2). P. 299-302.; R.B. Raffa, R.J. Tallarida, R Taylor. Fixeddose combinations for emerging treatment of pain // Expert Opin Pharmacother. 2012. V. 13(9). P. 1261-70.; N. Sambol, et al. Pharmacokinetics, safety, and tolerability of an NMDA-enhanced analgesic EN3231 in chronic pain patients who are slow and fast metabolizers of dextromethorphan // 10th World Congr Pain. San Diego. 2002. Abst 187-P183.; B.S. Galer, et al. MorphiDex(R) (morphine sulfate/dextromethorphan hydrobromide combination) in the treatment of chronic pain: Three multicenter, randomized, double-blind, controlled clinical trials fail to demonstrate enhanced opioid analgesia or reduction in tolerance // Pain. 2005. V. 115(3). P. 284.; Veterinary Anesthesia and Analgesia. 5th Ed. / Ed. by K.A. Grimm. - Wiley. 2015. 1072 p.; Veterinary Anesthetic and Analgesic Formulary. Animal care and use program. University of Colorado. URL: http://www.colorado.edu/innovate/sites/default/files/attached-files/CU%20Denver%20Analgesic%20%26%20Anesthetic%20Drug%20Formulary.pdf (дата обращения 10.02.2017); J.A.E. Hubbell at al. The use of sedatives, analgesic and anaesthetic drugs in the horse: An electronic survey of members of the American Association of Equine Practitioners (AAEP) // Equine Veterinary Journal. 2010. V. 42(6). P. 487-493.; J.A.E. Hubbell. Evaluation of midazolam-ketamine-xylazine infusion for total intravenous anesthesia in horses // American Journal of Veterinary Research. 2012. V. 73(4). P. 470-5.; A.K. Chan, C. W. Cheung, Y.K. Chong. Alpha-2 agonists in acute pain management // Expert Opin Pharmacother. 2010. V. 11(17). P. 2849-68.; J.A. Giovannitti, S.M. Thoms, J.J. Crawford. Alpha-2 Adrenergic Receptor Agonists: A Review of Current Clinical Applications // Anesth Prog. 2015. V. 62(1). P. 31-38.; D.D. Price, D.J. Mayer, J. Mao, F.S. Caruso. NMDA-receptor antagonists and opioid receptor interactions as related to analgesia and tolerance // J Pain Symptom Manage. 2000. V. 19(1). P. 7-11.; K. Subramaniam, B. Subramaniam, R. Steinbrook. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review // Anesth Analg. 2004. V. 99(2). P. 482-95.; D. Jamero, A. Borghol at al. The Emerging Role of NMDA Antagonists in Pain Management. U.S. Pharmacist. URL: http://www.medscape.com/viewarticle/744071_3 (дата обращения 02.02.2017).; C.S. Bonnet, A.S. Williams, et al. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis // Ann Rheum Dis. 2015. V. 74(1). P. 242-51.; D.R. Kirkpatrick et al. Transmission pathways and mediators as the basis for clinical pharmacology of pain // Expert Rev Clin Pharmacol. 2016. V. 4. P. 1-25.; A Study to Evaluate the Clinical Efficacy, Safety and Tolerability of ARX-F03 Sublingual Sufentanil/Triazolam Nano-Tab™ in Patients Undergoing an Elective Abdominal Liposuction Procedure // ClinicalTrials. AcelRx Pharmaceuticals, Inc. URL: https://clinicaltrials.gov/show/NCT00894699 (дата обращения 02.02.2017).; D. Perret, Z.D. Luo. Targeting voltagegated calcium channels for neuropathic pain management // Neurotherapeutics. 2009. V. 6(4). P. 679-92.; S. Goyal et al. Comparison of the Effects of Zonisamide, Ethosuximide and Pregabalin in the Chronic Constriction Injury Induced Neuropathic Pain in Rats // Ann Med Health Sci Res. 2015. V. 5(3). P. 189-96.; J.A. Fidler, Y.A. Jamal, et al. GABA antagonist, delays return of righting reflex in mice after isoflurane anesthesia but does not significantly alter dendritic spine density. 46th Annu Meet Soc Neurosci. San Diego // 2016. Abst 343.20.; P. Compton, P. Kehoe, K. Sinha. Gabaрentin improves cold-pressor pain responses in methadone-maintained patients // Drug Alcohol Depend. 2010. V. 109(1-3). P. 213-9.; N. Stoicea, D. Russell, G. Weidner, M. Durda, Sergio D. Bergese. Opioidinduced hyperalgesia in chronic pain patients and the mitigating effects of gabapentin // Front Pharmacol. 2015. V. 27. P. 96-104.; D.R. Maguire, C.P. France. Impact of efficacy at the μ-opioid receptor on antinociceptive effects of combinations of μ-opioid receptor agonists and cannabinoid receptor agonists // J Pharmacol Exp Ther. 2014. V. 351(2). P. 383-9.; F. Shen, P.R. Tsuruda, J.A. Smith, G.P. Obedencio, W.J. Martin. Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model // PLoS One. 2013. V. 8(9). P. 74891.; M.L. Banks, K.C. Rice, S.S. Negus. Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy // J Pharmacol Exp Ther. 2010. V. 335(2). P. 497-505.; J.X. Li, W. Koek, K.C. Rice, C.P. France. Effects of direct- and indirect-acting serotonin receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in rhesus monkeys // Neuropsychopharmacology. 2011. V. 36(5). P. 940-949.; Pain Management in Veterinary Practice / Editors: Christine M. Egger, Lydia Love, Tom Doherty. - NY: John Wiley & Sons, Ltd. 2014. 447 p.; D.L. Cichewicz, S.P. Welch, F.L. Smith. Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol // Eur J Pharmacol. 2005. V. 525 (1-3). P. 74-82.; R.G. Pertwee. Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities // Philos Trans R Soc Lond B Biol Sci. 2012. V. 367(1607). P. 3353-3363.; I.A. Aljuffali, C.-F. Lin, C.-H. Chen & J.-Y. Fang. The codrug approach for facilitating drug delivery and bioactivity // Expert Opinion on Drug Delivery. 2016. V. 13 (9). P. 1311-1325.; H.K. Dhooper. Opioid-Cannabinoid Co-drugs with Enhanced Analgesic and Pharmacokinetic Profile: PhD dissertation. University of Kentucky. 2010. 160 p.; J.L. Wiley, M.M. O'connell, M.E. Tokarz, M.J. Wright. Pharmacological effects of acute and repeated administration of Delta(9)-tetrahydrocannabinol in adolescent and adult rats // J Pharmacol Exp Ther. 2007. V. 320 (3). P. 1097-1105.; Abuse-Deterrent Opioids - Evaluation and Labeling Guidance for Industry. U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Clinical Medical. 2015. URL: http://www.fda.gov/downloads/Drugs/Guidances/UCM334743.pdf (дата обращения 11.02.2017); R. Moorman-Li, C.A. Motycka, L.D. Inge, et al. A review of abuse-deterrent opioids for chronic nonmalignant pain // P&T®. 2012. V. 37(7). P. 412-418.; H. Soltani, A. Pardakhty. Marketed New Drug Delivery Systems for Opioid Agonists/Antagonists Administration: A Rapid Overview // Addict Health. 2016. V. 8(2). P. 115-122.; L.R. Webster, E.A. Kopecky, M.D. Smith, A.B. Fleming. A Randomized, Double-Blind, Double-Dummy Study to Evaluate the Intranasal Human Abuse Potential and Pharmacokinetics of a Novel Extended-Release Abuse-Deterrent Formulation of Oxycodone // Pain Med. 2016. V. 17(6). P. 1112-30.; M.E. Schatman, L.R. Webster. The health insurance industry: perpetuating the opioid crisis through policies of costcontainment and profitability // J Pain Res. 2015. V. 18(8). P. 153-158.; D.A. Tompkins, R.K. Lanier, J.A. Harrison, E.C. Strain, G.E. Bigelow. Human abuse liability assessment of oxycodone combined with ultra-low-dose naltrexone // Psychopharmacology (Berl). 2010. V. 210(4) P. 471-480.; L.R. Webster, J. Markman, E.J. Cone, G. Niebler. Current and future development of extended-release, abuse-deter- rent opioid formulations in the United States // Postgraduate Medicine. 2017. V. 129(1). P. 102-110.; S.G. Severtsona, M.S. Ellis, S.P. Kurtzc. Sustained reduction of diversion and abuse after introduction of an abuse deterrent formulation of extended release oxycodone // Drug and Alcohol Dependence. 2016. V. 168 P. 219-229.; S.D. Passik. Issues in long-term opioid therapy: unmet needs, risks, and solutions // Mayo Clin Proc. 2009. V. 84(7). P. 593-601.; I. Kissin. The Development of New Analgesics Over the Past 50 Years: A Lack of Real Breakthrough Drugs // Anesthesia and analgesia. 2010. V. 110(3). P. 780-789.; J.E. Barrett. Perspectives and Trends in Pharmacological Approaches to the Modulation of Pain // Adv Pharmacol. 2016. V. 75. P. 1-33.; https://www.pharmjournal.ru/jour/article/view/427

  8. 8
    Academic Journal

    المصدر: Drug development & registration; № 3 (2018); 114-128 ; Разработка и регистрация лекарственных средств; № 3 (2018); 114-128 ; 2658-5049 ; 2305-2066

    وصف الملف: application/pdf

    Relation: https://www.pharmjournal.ru/jour/article/view/614/609; База данных Integrity. [Baza dannykh Integrity. [The Integrity database]. Available at: https://integrity.thomson-pharma.com/ integrity/xmlxsl/pk_home.util_home (accessed 14.05.2018).; Соснов А. В., Семченко Ф. М., Власов М. И., Тохмахчи В. Н., Соснова А. А., Кинзирский А. С. Разработка неинъекционных препаратов центрального действия для неотложной терапии // Разработка и регистрация лекарственных средств. 2018. № 1(22). С. 92-111. [Sosnov A. V., Semchenko F. M., Vlasov M. I., Tohmahchi V. N.,Sosnova A. A., Kinzirsky A. S. Razrabotka nein'ektsionnykh preparatov tsentral'nogo deistviya dlya neotlozhnoi terapii // Razrabotka i registratsiya lekarstvennykh sredstv. [Development of non-injectable medicinal drugs acting on CNS for emergency therapy // Drug Development & Registration]. 2018. № 1(22). P. 92-111].; Joint Meeting of Anesthetic and Analgesic Drug Products Advisory Committee and Drug Safety and Risk Management Advisory Committee. 2016. FDA Briefing Document. 236 p.; Piper B. J., Shah D. T., Simoyan O. M., McCall K. L., Nichols S. D. Trends in Medical Use of Opioids in the U.S., 2006-2016 // Am J Prev Med. 2018. P. 1-9.; Соснов А. В., Семченко Ф. М., Власов М. И., Тохмахчи В. Н., Соснова А. А. Развитие комплексной фармакотерапии сильной и средней боли. Ч. 1. Мультитаргетное комбинирование опиоидов и ненаркотических анальгетиков центрального действия // Разработка и регистрация лекарственных средств. 2017. № 2(19). С. 176-187. [Sosnov A. V., Semchenko F. M., Vlasov M. I., Tohmahchi V. N., Sosnova A. A. Razvitie kompleksnoi farmakoterapii sil'noi i srednei boli. Ch. 1. Mul'titargetnoe kombinirovanie opioidov i nenarkoticheskikh anal'getikov tsentral'nogo deistviya // Razrabotka i registratsiya lekarstvennykh sredstv. [Development of complex pharmacotherapy of severe and moderate pain. Part 1. Multitargeted combination of opioids and non-opioid analgesics with central effects // Drug Development & Registration. 2017. № 2(19). Р. 176-187].; Наркомания, преступность и мятежники. Транснациональная угроза афганского опия. United Nations Office on Drugs and Crime (UNODC). 2009. 23 с. [Narkomaniya, prestupnost' i myatezhniki. Transnatsional'naya ugroza afganskogo opiya. [Afghanistan Opium Survey. United Nations Office on Drugs and Crime (UNODC)]. 2009. 23 p.].; Бескаравайная Т. Наркотические анальгетики в России получают не более 7-8% нуждающихся // Медвестник. 16.06.2015. [Beskaravainaya T. Narkoticheskie anal'getiki v Rossii poluchayut ne bolee 7-8% nuzhdayushchikhsya. [Narcotic algesics in Russia receive no more than 7-8% patients of those in need] // Medvednik. 06.16.2015].; Кононова С. В., Лебедева М. В. Анализ лекарственного обеспечения онкологических больных наркотическими анальгетиками в амбулаторных условиях в Нижегородской области // Фармация и фармакология. 2015. № 4(11). С. 43-46. [Kononova S. V., Lebedeva M. V. Analiz lekarstvennogo obespecheniya onkologicheskikh bol'nykh narkoticheskimi anal'getikami v ambulatornykh usloviyakh v Nizhegorodskoĭ oblasti // Farmatsiya i farmakologiya [Analysis of drug provision for oncological patients with narcotic analgesics in outpatient settings in the Nizhny Novgorod region // Pharmacy and Pharmacology]. 2015. № 4(11). P. 43-46].; Соснов А. В., Голубев С. С., Пункевич Б. С., Садовников С. В., Семченко Ф. М., Тохмахчи В. Н., Соснова А. А. Оценка потребности российской федерации в сильнодействующих анальгетиках // Разработка и регистрация лекарственных средств. 2016. № 2(15). C. 202-215. [Sosnov A. V., Golubev S. S., Punkevich B. S., Sadovnikov S. V., Semchenko F. M., Tohmahchi V. N., Sosnova A. A. Otsenka potrebnosti rossiiskoi federatsii v sil'nodeistvuyushchikh anal'getikakh // Razrabotka i registratsiya lekarstvennykh sredstv. [Assessment of the Russian Federation requirement in potent analgesics // Drug Development & Registration]. 2016. № 2(15). P. 76-187].; FDA Analysis of Long-Term Trends in Prescription Opioid Analgesic Products: Quantity, Sales, and Price Trends / FDA Report. 2018. P. 1-12.; CDC Provisional Drug Overdose Death Counts. Available at: https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm (accessed 05.07.2018).; Katz J. The First Count of Fentanyl Deaths in 2016: Up 540% in Three Years. The New York Times. 02.09.2017. Available at: https://www.nytimes. co m / inte r a c ti ve / 2017/0 9/02 /upsh ot / fent any l - drug - overdose - deaths. html (accessed 14.05.2018).; NIH launched the HEAL Initiative. USA NIH. 2018. Available at: https://www.nih.gov/research-training/medical-research-initiatives/heal-initiative (accessed 14.05.2018).; FDA Opioids Action Plan. USA FDA. 2017. Available at: https://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/ucm4 8 4714. htm (accessed 18.05.2018).; Volkow N., Collins F. The Role of Science in Addressing the Opioid Crisis // New England Journal of Medicine. 2017. V. 377(4). P. 391-394.; Chan S., McCarthy D., Li J., Palczewski K., Yuan Sh. Designing Safer Analgesics via μ-Opioid Receptor Pathways // Trends Pharmacol Sci. 2017. V. 38(11). P. 1016-1037.; Manglik A., Lin H., Aryal D. Shoichet B.K. et al. Structure-based discovery of opioid analgesics with reduced side effects // Nature. 2016. V. 537(7619). P. 185-190.; Viscusia E. R., Websterb L., Kussc M., Danielsc S., Bolognesed J. A., Zuckermand S., Soergele D.G., Subache R. A., Cooke E., Skobierandae F. A randomized, phase 2 study investigating TRV130, a biased ligand of the m-opioid receptor, for the intravenous treatment of acute pain // Pain. 2016. V. 157(1). P. 264-272.; Roth B. L, Irwin J. J., Shoichet B. K. Discovery of new GPCR ligands to illuminate new biology // Nature Chem. Biology. 2017. V. 13 (11). P. 1143-1151.; Soergel D. G., Subach R. A., Burnham N., Lark M. W., James I.E., Sadler B. M., Skobieranda F., Violin J. D., Webster L. R. Biased agonism of the m-opioid receptor by TRV130 increases analgesia and reduces on-target adverse effects vs morphine: A randomized, double-blind, placebo-controlled, crossover study in healthy volunteers // Pain. 2014. V. 155. P. 1829-35.; Siuda E. R, Carr R., Rominger D. H., Violin J. D. Biased mu-opioid receptor ligands: a promising new generation of pain therapeutics // Neurosciences. Current Opinion in Pharmacology. 2017. V. 32. P. 77-84.; Ok H. G., Kim S. Y., Lee S. J., Kim T. K., Huh B. K., Kim K. H. Can oliceridine (TRV130), an ideal novel receptor G protein pathway selective (GPS) modulator, provide analgesia without opioid-related adverse reactions? // Korean J Pain. 2018. V. 31(2). P. 73-79.; Mori T., Kuzumaki N., Arima T. et al. Usefulness for the combination of G-protein- and β-arrestin-biased ligands of μ-opioid receptors: Prevention of antinociceptive tolerance // Mol Pain. 2017. V. 13. P. 1-9.; Глава ФСКН насчитал в России 7 млн наркоманов // BBC News. Русская служба. 26.06.2015. [Glava FSKN naschital v Rossii 7 mln narkomanov. BBC News. Russkaya sluzhba. 26.06.2015. [The head of the Federal Drug Control Service counted 7 million drug addicts in Russia // BBC News. Russian service]. Available at: https://www.bbc.com/ russian/russia/2015/06/150626 _drug _ addicts_number (accessed 14.05.2018).; Reichle C. W., Smith G. M., Gravenstein J. S., Macris S. G., Beecher H. K. Comparative analgesic potency of heroin and morphine in postoperative patients // J. Pharmacol. Exp. Ther. 1962. V. 136 (1). P. 43-46.; Судебно-медицинская оценка токсичности опиоидов у взрослых и детей с персистирующей болью: Методические рекомендации / ФГБУ «Российский центр судебно-медицинской экспертизы» Министерства здравоохранения Российской Федерации. 2015. М. 59 с. [Sudebno-meditsinskaya otsenka toksichnosti opioidov u vzroslykh i detei s persistiruyushchei bol'yu: Metodicheskie rekomendatsii / FGBU «Rossiiskii tsentr sudebno-meditsinskoi ekspertizy» Ministerstva zdravookhraneniya Rossiiskoi Federatsii. [Guidelines. Forensic assessment of the toxicity of opioids in adults and children with persistent pain / FGBU «Russian Center for Forensic Medical Examination» of the Ministry of Health of the Russian Federation. 2015. Moscow. 59 p.].; Публикации в порядке обсуждения направлений развития анальгетиков в РФ. (A) Мантуров: для выращивания опийных растений в РФ потребуется 200 га земли в южном регионе // ТАСС. 01.07.2017. [Publikatsii v poryadke obsuzhdeniya napravlenii razvitiya anal'getikov v RF. (A) Manturov: dlya vyrashchivaniya opiinykh rastenii v RF potrebuetsya 200 ga zemli v yuzhnom regione [Publications in the order of discussion in directions of analgesics development in the Russian Federation. (A) Manturov: 200 hectares of land in the southern region will be needed for the cultivation of opium plants in the Russian Federation] // TASS. 01.07.2017]. Available at: http:// tass.ru/ekonomika/4299391 (accessed 24.05.2018); (Б) Ростех готов производить лекарства из субстанций с содержанием опиатов // ТАСС. 10.08.2017. [(B) Rostekh gotov proizvodit' lekarstva iz substantsii s soderzhaniem opiatov. (B) Rostech is ready to produce medicines from substances containing opiates] // TASS. 08/10/2017]. Available at: http:// tass.ru/obschestvo/4397683 (accessed 24.05.2018).; Amini M. Afghanistan’s relentless opium woes have a 'new seed in town, and it comes from China. World News. CNDC. 25.03.2017. Available at: https://www.cnbc.com/2017/03/24/afghanistans-relentless-opium-woes-have-a-new-seed-in-town-and-it-comes-from-china. html (accessed 24.05.2018).; Соснов А. В., Садовников С. В., Семченко Ф. М., Руфанов К. А., Тохмахчи В. Н., Соснова А. А., Тюрин И. А. Сильнодействующие ненаркотические анальгетики как направление развития фармацевтики // Разработка и регистрация лекарственных средств. 2016. № 1(14). С. 196-206. [Sosnov A. V., Sadovnikov S. V., Semchenko F. M., Rufanov K. A., Tohmakhchi V. N., Sosnova A. A., Tyurin I. A. Sil'nodeistvuyushchie nenarkoticheskie anal'getiki kak napravlenie razvitiya farmatsevtiki // Razrabotka i registratsiya lekarstvennykh sredstv. [Strong-acting non-narcotic analgesics as direction of development of pharmaceutics // Drug Development & Registration]. 2016. № 1(14). P. 196-206].; White J., Irvine R. Mechanisms of fatal opioid overdose // Addiction. 1999. V. 94(7). P. 961-972.; Breslow J., Monrow A., Daly J., Meissier J., Gauyhan J., Alder M., Eisenstein T. Morphine not trauma sensitizes to systemic Acinetobacter baumannii infection // J NeuroImmune Pharmacol. 2011. V. 6(4). P. 551-65.; Morphine-Induced Immunosuppression, From Brain to Spleen. NIDA. Available at: https://www.drugabuse.gov/news-events/nida-notes/2008/06/morphine-induced-immunosuppression-brain-to-sple en (accessed 24.05.2018).; Sacerdote P., Franchi S., Panerai A. E. Non-analgesic effects of opioids: me-chanisms and potential clinical re-levance of opioid-induced immunodepression // Curr Pharm Des. 2012. V. 18(37). P. 6034-42.; Bimonte S., Barbieri А., Rea D. et al. Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression // BioMed Research International. 2015. V. 2015. Article ID 161508. P. 1-8.; Gupta К., Kshirsagar S., Chang L. et al. Morphine Stimulates Angiogenesis by Activating Proangiogenic and Survivalpromoting Signaling and Promotes Breast Tumor Growth // Cancer Research. 2002. V. 62. P. 4491-4498.; DiDonato K., Palmer P.P., Morris T.E., Walker J., Casamayor M., Hennebert M. Intravenous administration of morphine in the emergency room inflicts a substantial economic burden in the EU5. ISPOR 19th Annual European Congress. 2016. Poster PSY45.; Kane-Gill S. L. The cost of opioid-related adverse drug events // Journal of pain & palliative care pharmacotherapy. 2014. V. 28(3). P. 282-293.; Report of the International Narcotics Control Board on the Availability of Internationally Controlled Drugs: Ensuring Adequate Access for Medical and Scientific Purposes. 2010. Available at: http://www.incb.org/ documents/Publications/AnnualReports/AR2010/Supplement-AR10_availability_English.pdf (accessed 24.05.2018).; Williams A., Baird E. Special Considerations for the Treatment of Pain from Torture and War // Curr Anesthesiol Rep. 2016. V. 6. P. 319-326.; Rankovic Zoran. CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure // J. Med. Chem. 2015. V. 58 (6). P. 2584-2608.; Andrés A., Rosés M., Ràfols C., Bosch E., Espinosa S., Segarra V., Huerta J. M. Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts // Eur J Pharm Sci. 2015. V. 30(76). P. 181-191.; Morgan R. W., Nicholson K. L. Characterization of the Antinociceptive Effects of the Individual Isomers of Methadone Following Acute and Chronic Administration // Behav Pharmacol. 2011. V. 22(5-6). P. 548-57.; Weltrowskaa G., Lemieuxa C., Chunga N. N., Guo J. J., Wilkesa B. C., Schiller P. W. Carba-carfentanil (trans isomer): a μ opioid receptor (MOR) partial agonist with a distinct binding mode // Bioorg Med Chem. 2014. V. 22(17). P. 4581-4586.; Thompson R. G., Menking D., Valdes J. J. Opiate receptor binding properties of carfentanil. CRDEC Aberdeen Proving Ground. 1987. P. 1-20.; Mandema J. W., Stanski D. R. Population pharmacodynamic model for ketorolac analgesia // Clin Pharmacol Ther. 1996. V. 60(6). P. 619-635.; Critical review of Ketamine 34th ECDD 2006/4.3. Available at: https://www.drugbank.ca/unearth/q?utf8=%E2% (accessed 24.05.2018).; Volpe D. A., McMahon Tobin G. A., Mellon R. D., Katki A. G., Parker R. J., Colatsky T., Kropp T. J., Verbois S. L. Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs // Regulatory Toxicology and Pharmacology. 2011. V. 59. P. 385-390.; Zhang B., Zhang T., Sromek A. W., Scrimale T., Bidlack J. M., Neumeyer J. L. Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors // Bioorg Med Chem. 2011. V. 19(9). P. 2808-2816.; Mather L. E. Opioids: a pharmacologist’s delight // Clin Exp Pharmacol Physiol. 1995. V. 22. P. 833-836.; LogD Predictor. ChemAxon. Available at: https:// disco.chemaxon.com/apps/ demos/ logd/ (accessed 24.05.2018).; Medzihradsky F., Emmerson P. J., Mousigian C. A. Lipophilicity of Opioids Determined by a Novel Mic-romethod // JPM. 1992. V. 27 (2). P. 67-69.; DrugBank database. Available at: https://www. drugbank.ca/drugs (accessed 24.05.2018).; Small Animal Toxicology / Ed. by Peterson M.E. and Talcott P.A. 2006. 1190 p.; Bostro E., Hammarlund-Udenaes M., Simonsson U. S. H. Blood-Brain Barrier Transport Helps to Explain Discrepancies in In Vivo Potency between Oxycodone and Morphine // Anesthesiology. 2008. V. 108. P. 495-505.; MacKenzie M., Zed P. J, Ensom M. H. H. Opioid Pharmacokinetics-Pharmacodynamics: Clinical Implications in Acute Pain Management in Trauma // Annals of Pharmacotherapy. 2016. P. 1-10; Vuyk J., Schraag S. Advances in Modelling and Clinical Application of Intravenous Anaesthesia. - Springer Science & Business Media. 2012. 280 p.; Steagall P. V. M, Pelligand L., Giordano T., Auberger C., Sear J. W, Luna S. P. L., Taylor P. M. Pharmacokinetic and pharmacodynamic modelling of intravenous, intramuscular and subcutaneous buprenorphine in conscious cats // Veterinary Anaesthesia and Analgesia. 2013. V. 40(1). P. 83-95.; Martini C.H., Olofsen E., Yassen A., Aarts L., Dahan A. Pharmacokinetic-pharmacodynamics modeling in acute and chronic pain: an overview of the recent literature // Expert Rev Clin Pharmacol. 2011. V. 4(6). P. 719-728.; Sax's Dangerous Properties of Industrial Materials. 11th ed. / Ed. by R.J. Lewis. (Lewis Information Systems, Inc.). Hoboken, NJ: John Wiley & Sons. 2004.; Рудько О. И., Климов Е.А., Соболев В. В., Соснов А. В., Руфанов К. А., Семченко Ф. М. Исследование влияния интраназального введения препарата дексмедетомидин на болевую чувствительность // Разработка и регистрация лекарственных средств. 2017. № 2(19). С. 238-243. [Rudko O. I., Klimov E. A., Sobolev V. V., Sosnov A. V., Rufanov K. A., Semchenko F. M. Issledovanie vliyaniya intranazal'nogo vvedeniya preparata deksmedetomidin na bolevuyu chuvstvitel'nost' // Razrabotka i registratsiya lekarstvennykh sredstv. [The study of effects of the intranasal dexmedetomidine administration on pain sensitivity // Drug Development & Registration]. 2017. № 2(19). P. 238-243].; Wolf R. W. Army Medicine Fighting Opioid Overuse for a Decade. Army Medicine. 09.01.2018. Available at: https:// w w w. ar my. m il /ar ti cl e /19 8922 /ar my_ m e dicin e _ f ighting _ opioid _ overus e _ for_a_decade (accessed 24.05.2018).; Experimental Vaccine Blocks Effects of Heroin in Mice. US Military’s HIV Research Program (MHRP). Available at: https://www.hivresearch.org (accessed 24.05.2018).; Baumann M., Pasternak G. Novel Synthetic Opioids and Overdose Deaths: Tip of the Iceberg? // Neuropsychopharmacology. 2018. V. 43. P. 216-217.; Уйба В. В., Криворотов Д. В., Радилов А. С., Рембовский В. Р., Дулов С. А., Кузнецов В. А., Ерофеев Г. Г., Мартинович Н. Н., Соснов А. В. Антагонисты опиоидных рецепторов. От настоящего к будущему // Медицина экстремальных состояний. 2018. В печати. [Uyba V. V., Krivorotov D. V., Zabelin M. V., Radilov A. S., Rembovskiy V. R., Dulov S. A., Kuznetsov V. A., Erofeev G. G., Martinovitch N. N., Sosnov A. V. Antagonisty opioidnykh retseptorov. Ot nastoyashchego k budushchemu // Meditsina ekstremal'nykh sostoyanii. [Opioid receptor antagonists. from the present to the future // Medicine of extreme conditions]. 2018. In press.].; https://www.pharmjournal.ru/jour/article/view/614

  9. 9
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20