المؤلفون: Matthew J. Cato, Peter J. Manley, Christopher J. Dinsmore, Jixin Wang, B. Wesley Trotter, M. Brad Nolt, Bing Li, Robert H. Spencer, Mark T. Bilodeau, Gary L. Stump, Scott E. Wolkenberg, Rebecca B. White, Kausik K. Nanda, Laszlo Kiss, George D. Hartman, Craig W. Lindsley, Christopher P. Regan, Stefanie A. Kane, Zhicai Wu, Suzie Yeh, Joseph J. Lynch, Nathan R. Kett

المصدر: Bioorganicmedicinal chemistry letters. 27(4)

مصطلحات موضوعية: 0301 basic medicine, Pyridines, Clinical Biochemistry, Pharmaceutical Science, 030204 cardiovascular system & hematology, Pharmacology, Selective inhibition, Biochemistry, 03 medical and health sciences, Kv1.5 Potassium Channel, Structure-Activity Relationship, 0302 clinical medicine, Pharmacokinetics, In vivo, Drug Discovery, medicine, Humans, Molecular Biology, Proarrhythmia, Chemistry, Drug discovery, Organic Chemistry, Atrial fibrillation, medicine.disease, 030104 developmental biology, Delayed rectifier, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28d78944ff68aea790d3850958003ea
https://pubmed.ncbi.nlm.nih.gov/28131713

المؤلفون: Zhijian Zhao, M. Brad Nolt, Scott E. Wolkenberg

المصدر: Tetrahedron Letters. 49:3137-3141

مصطلحات موضوعية: Reaction conditions, Organic Chemistry, Quinoline, Halide, Substrate (chemistry), Highly selective, Biochemistry, Combinatorial chemistry, Coupling reaction, chemistry.chemical_compound, chemistry, Drug Discovery, Organic chemistry, Reactivity (chemistry), Derivatization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::432f4bcc77ccd50ff8e12a4a68691f14
https://doi.org/10.1016/j.tetlet.2008.03.040

المؤلفون: Craig W. Lindsley, Scott E. Wolkenberg, Ray T. McClain, Sandor L. Varga, M. Brad Nolt, Mark A. Smiley

المصدر: Tetrahedron. 62:4698-4704

مصطلحات موضوعية: Reaction sequence, Chemistry, Yield (chemistry), Organic Chemistry, Drug Discovery, Organic chemistry, General Medicine, Biochemistry, Combinatorial chemistry, Microwave assisted

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4ec307a05e424fdd54ccafa7a7815b
https://doi.org/10.1016/j.tet.2005.12.065

المؤلفون: Gopinathan Anilkumar, Jianghe Deng, Ashwin Rao, Rajesh Goswami, Tianan Fang, M. Brad Nolt, Kavirayani R. Prasad, Yulian Zhang, Bin Yang, Yongzhong Wu, Franklin A. Davis

المصدر: Phosphorus, Sulfur, and Silicon and the Related Elements. 180:1109-1117

مصطلحات موضوعية: Inorganic Chemistry, chemistry.chemical_compound, Enantiopure drug, Chemistry, Organic Chemistry, Chemical manipulation, Enantioselective synthesis, Organic chemistry, Piperidine, Biochemistry, Pyrrolidine, Amine derivatives

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::27d1aa22f53136073bf07f0f838f59fa
https://doi.org/10.1080/10426500590910648

المؤلفون: Lei Ma, James C. Barrow, Matthew A. Seager, George D. Hartman, Kenneth A. Koeplinger, Feng V. Yang, M. Brad Nolt, William J. Ray, Zhijian Zhao, Craig W. Lindsley, William D. Shipe, David D. Wisnoski, Jaime L. Bunda, Marion Wittmann

المصدر: Bioorganicmedicinal chemistry letters. 20(2)

مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Carboxylic acid, Clinical Biochemistry, Allosteric regulation, Carboxylic Acids, Pharmaceutical Science, Plasma protein binding, Biochemistry, Chemical synthesis, Small Molecule Libraries, Allosteric Regulation, Drug Discovery, medicine, Animals, Humans, Molecular Biology, chemistry.chemical_classification, Chemistry, Organic Chemistry, Receptor, Muscarinic M1, Blood Proteins, Quinolone, Rats, Free fraction, Quinolines, Molecular Medicine, Amine gas treating, Selectivity, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baac57aec52748a7fc2c37d686ff40d
https://pubmed.ncbi.nlm.nih.gov/20004574

المؤلفون: Zhijian Zhao, Scott E. Wolkenberg, M. Brad Nolt

المصدر: ChemInform. 39

مصطلحات موضوعية: Reaction conditions, chemistry.chemical_compound, chemistry, Quinoline, Halide, Substrate (chemistry), Reactivity (chemistry), General Medicine, Derivatization, Highly selective, Combinatorial chemistry, Coupling reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0edacb3188eebb630de48e3f8041951d
https://doi.org/10.1002/chin.200834151

المؤلفون: William D. Shipe, M. Brad Nolt, Craig W. Lindsley, Zhijian Zhao, Scott E. Wolkenberg, Feng Yang

المصدر: ChemInform. 38

مصطلحات موضوعية: Pharmacology, Chemistry, Organic Chemistry, Side product, Organic chemistry, General Medicine, Microwave assisted, Combinatorial chemistry, Microwave, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a968f40c0a7f9645ac81239a31e44f
https://doi.org/10.1002/chin.200719241

المؤلفون: John H. Eardley, Franklin A. Davis, Yongzhong Wu, Danyang Li, Bin Yang, Seung H. Lee, Kerisha A. Bowen, Kavirayani R. Prasad, M. Brad Nolt

المصدر: ChemInform. 36

مصطلحات موضوعية: Stereochemistry, Chemistry, Enantioselective synthesis, Organic chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::435271c58128ec15cb0e7d3ff33e3722
https://doi.org/10.1002/chin.200533085

المؤلفون: M. Brad Nolt, Yongzhong Wu, Franklin A. Davis, Kavirayani R. Prasad

المصدر: ChemInform. 34

مصطلحات موضوعية: Allosedridine, Magnetic Resonance Spectroscopy, Stereochemistry, Potassium, Organic Chemistry, Condensation, Enantioselective synthesis, chemistry.chemical_element, Stereoisomerism, General Medicine, Amides, Biochemistry, Enantiopure drug, Piperidines, chemistry, Sulfoxides, Organic chemistry, Indicators and Reagents, heterocyclic compounds, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c584b2c1b4c95989d18ba48de93047
https://doi.org/10.1002/chin.200335083