المؤلفون: Smidt, Jakob Melgaard, Märcher, Anders, Skaanning, Mads Koch, El-Chami, Kassem, Teodori, Laura, Omer, Marjan, Kjems, Jørgen, Gothelf, Kurt V.

المصدر: Smidt , J M , Märcher , A , Skaanning , M K , El-Chami , K , Teodori , L , Omer , M , Kjems , J & Gothelf , K V 2024 , ' Dual-Targeting of the HER2 Cancer Receptor with an Antibody-Directed Enzyme and a Nanobody-Guided MMAE Prodrug Scaffold ' , ChemBioChem , vol. 25 , no. 18 , e202400437 . https://doi.org/10.1002/cbic.202400437

مصطلحات موضوعية: ADEPT, Bioconjugation, Nanobody, Prodrug, aTNA

الاتاحة: https://pure.au.dk/portal/en/publications/534222f3-d01a-4920-96d0-68d2121c539d
https://doi.org/10.1002/cbic.202400437
http://www.scopus.com/inward/record.url?scp=85201526031&partnerID=8YFLogxK

المؤلفون: Dinesen, Anders, Andersen, Veronica L, Elkhashab, Marwa, Pilati, Diego, Bech, Pernille, Fuchs, Elisabeth, Samuelsen, Torbjørn R, Winther, Alexander, Cai, Yunpeng, Märcher, Anders, Wall, Archie, Omer, Marjan, Nielsen, Jesper S, Chudasama, Vijay, Baker, James R, Gothelf, Kurt V, Wengel, Jesper, Kjems, Jørgen, Howard, Kenneth A

المصدر: Bioconjugate Chemistry , 35 (2) pp. 214-222. (2024)

مصطلحات موضوعية: Biopolymers, Functionalization, Half-Life, Molecular Properties, Peptides And Proteins

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10187389/18/Baker_bc3c00491_si_001.pdf; https://discovery.ucl.ac.uk/id/eprint/10187389/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10187389/17/Baker_dinesen-et-al-2024-an-albumin-holliday-junction-biomolecular-modular-design-for-programmable-multifunctionality-and.pdf
https://discovery.ucl.ac.uk/id/eprint/10187389/18/Baker_bc3c00491_si_001.pdf
https://discovery.ucl.ac.uk/id/eprint/10187389/

المؤلفون: Hansen, Rikke A., Märcher, Anders, Pedersen, Kristian Nørgaard, Gothelf, Kurt V.

المصدر: Hansen , R A , Märcher , A , Pedersen , K N & Gothelf , K V 2023 , ' Insertion of Chemical Handles into the Backbone of DNA during Solid-Phase Synthesis by Oxidative Coupling of Amines to Phosphites ' , Angewandte Chemie - International Edition , vol. 62 , no. 26 , e202305373 . https://doi.org/10.1002/anie.202305373

مصطلحات موضوعية: Antibody, Bioconjugation, Oligonucleotide Synthesis, Phosphoramidate, Solid-Phase

الاتاحة: https://pure.au.dk/portal/en/publications/4f2b1d5b-e556-46e4-99f2-77a60a858f5a
https://doi.org/10.1002/anie.202305373
http://www.scopus.com/inward/record.url?scp=85159441680&partnerID=8YFLogxK

المؤلفون: Dinesen, Anders, Winther, Alexander, Wall, Archie, Märcher, Anders, Palmfeldt, Johan, Chudasama, Vijay, Wengel, Jesper, Gothelf, Kurt V, Baker, James R., Howard, Kenneth A

المصدر: Dinesen , A , Winther , A , Wall , A , Märcher , A , Palmfeldt , J , Chudasama , V , Wengel , J , Gothelf , K V , Baker , J R & Howard , K A 2022 , ' Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly ' , Bioconjugate Chemistry , vol. 33 , no. 2 , pp. 333-342 . https://doi.org/10.1021/acs.bioconjchem.1c00561

وصف الملف: application/pdf

الاتاحة: https://pure.au.dk/portal/en/publications/f31b85dc-42d3-494b-b9d6-04a5b6bec945
https://doi.org/10.1021/acs.bioconjchem.1c00561
https://pure.au.dk/ws/files/367110614/dinesen-et-al-2022-albumin-biomolecular-drug-designs-stabilized-through-improved-thiol-conjugation-and-a-modular-locked.pdf

المؤلفون: Märcher, Anders, Kumar, Vipin, Andersen, Veronica L., El-Chami, Kassem, Nguyen, Thuy J.D., Skaanning, Mads K., Rudnik-Jansen, Imke, Nielsen, Jesper S., Howard, Kenneth A., Kjems, Jørgen, Gothelf, Kurt V.

المصدر: Märcher , A , Kumar , V , Andersen , V L , El-Chami , K , Nguyen , T J D , Skaanning , M K , Rudnik-Jansen , I , Nielsen , J S , Howard , K A , Kjems , J & Gothelf , K V 2022 , ' Functionalized Acyclic (l)-Threoninol Nucleic Acid Four-Way Junction with High Stability In Vitro and In Vivo ' , Angewandte Chemie - International Edition , vol. 61 , no. 24 , 202115275 . https://doi.org/10.1002/anie.202115275

مصطلحات موضوعية: aTNA, DNA, Holliday Junction, Nanostructures, CELLS, NANOBODIES, DNA NANOSTRUCTURES, PROTEINS, DELIVERY, Butylene Glycols, Nucleic Acids/chemistry, Oligonucleotides, RNA/chemistry, Amino Alcohols/chemistry, Nucleic Acid Conformation

Relation: https://pure.au.dk/portal/da/publications/functionalized-acyclic-lthreoninol-nucleic-acid-fourway-junction-with-high-stability-in-vitro-and-in-vivo(2c7f5436-6060-4d45-9a07-53de17409047).html

الاتاحة: https://pure.au.dk/portal/da/publications/functionalized-acyclic-lthreoninol-nucleic-acid-fourway-junction-with-high-stability-in-vitro-and-in-vivo(2c7f5436-6060-4d45-9a07-53de17409047).html
https://doi.org/10.1002/anie.202115275
http://www.scopus.com/inward/record.url?scp=85128196548&partnerID=8YFLogxK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324938/pdf/ANIE-61-0.pdf

المؤلفون: Teodori, Laura, Omer, Marjan, Märcher, Anders, K. Skaanning, Mads, L. Andersen, Veronica, S. Nielsen, Jesper, Oldenburg, Emil, Lin, Yuchen, V. Gothelf , Kurt, Kjems, Jørgen

المصدر: Journal of Biological Methods; Vol. 9 No. 1 (2022); e159 ; 2326-9901

مصطلحات موضوعية: bioconjugation, click chemistry, site-specificity, nanobodies, super-resolution microscopy

وصف الملف: text/html; application/pdf

Relation: https://polscientific.com/jbm/index.php/jbm/article/view/381/445; https://polscientific.com/jbm/index.php/jbm/article/view/381/446; https://polscientific.com/jbm/index.php/jbm/article/view/381

الاتاحة: https://polscientific.com/jbm/index.php/jbm/article/view/381
https://doi.org/10.14440/jbm.2022.381

المؤلفون: Dinesen, Anders, Winther, Alexander, Wall, Archie, Märcher, Anders, Palmfeldt, Johan, Chudasama, Vijay, Wengel, Jesper, Gothelf, Kurt Vesterager, Baker, James R., Howard, Ken

المصدر: Dinesen , A , Winther , A , Wall , A , Märcher , A , Palmfeldt , J , Chudasama , V , Wengel , J , Gothelf , K V , Baker , J R & Howard , K 2022 , ' An Albumin Biomolecular Drug Design Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Assembly ' , Controlled Release Society 2022 Annual Meeting , Montreal , Canada , 11/07/2022 - 15/07/2022 .

مصطلحات موضوعية: Drug conjugate, Protein/peptide, Stability, Toxicity

Relation: https://pure.au.dk/portal/en/publications/835fb78c-9eb6-4bc4-84f6-7855f8e8660a

الاتاحة: https://pure.au.dk/portal/en/publications/835fb78c-9eb6-4bc4-84f6-7855f8e8660a

المؤلفون: Märcher, Anders, Gothelf, Kurt V.

المساهمون: Hussack, Greg, Henry, Kevin A.

المصدر: Märcher , A & Gothelf , K V 2022 , Affinity-Guided Site-Selective Labeling of Nanobodies with Aldehyde Handles . in G Hussack & K A Henry (eds) , Single-Domain Antibodies : Methods in Molecular Biology . vol. 2446 , Humana Press , New York , Methods in Molecular Biology , vol. 2446 , pp. 345-356 . https://doi.org/10.1007/978-1-0716-2075-5_17

مصطلحات موضوعية: Aldehyde handle, His-tag, Metal complexation, Nanobodies, Protein conjugation, Affinity Labels, Proteins/chemistry, Aldehydes/chemistry, Fluorescent Dyes, Single-Domain Antibodies/chemistry

الاتاحة: https://pure.au.dk/portal/da/publications/affinityguided-siteselective-labeling-of-nanobodies-with-aldehyde-handles(2412851e-6742-456e-849e-e9919fbb0668).html
https://doi.org/10.1007/978-1-0716-2075-5_17
http://www.scopus.com/inward/record.url?scp=85124623162&partnerID=8YFLogxK

المؤلفون: Hansen, Rikke Asbæk, Märcher, Anders, Gothelf, Kurt Vesterager

المصدر: Hansen , R A , Märcher , A & Gothelf , K V 2022 , ' One-Step Conversion of NHS Esters to Reagents for Site-Directed Labeling of IgG Antibodies ' , Bioconjugate Chemistry , vol. 33 , no. 10 , pp. 1811-1817 . https://doi.org/10.1021/acs.bioconjchem.2c00392

مصطلحات موضوعية: Esters, Immunoglobulin G, Indicators and Reagents, State Medicine

الاتاحة: https://pure.au.dk/portal/en/publications/53c9f570-1f24-4ab7-844d-d62285d4d74e
https://doi.org/10.1021/acs.bioconjchem.2c00392

المؤلفون: Märcher, Anders

المصدر: Märcher, A 2021, Development and use of multifunctional biomolecular conjugates . Aarhus Universitet .

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pure_au_____::f93c14d0fcb836baa4521ec9a723ea4a
https://pure.au.dk/portal/da/publications/development-and-use-of-multifunctional-biomolecular-conjugates(aa7e883b-fe57-4773-ae5f-a99c6ae940f1).html

المؤلفون: Märcher, Anders, Nijenhuis, Minke A.D., Gothelf, Kurt V.

المصدر: Märcher , A , Nijenhuis , M A D & Gothelf , K V 2021 , ' A Wireframe DNA Cube : Antibody Conjugate for Targeted Delivery of Multiple Copies of Monomethyl Auristatin E ' , Angewandte Chemie - International Edition , vol. 60 , no. 40 , pp. 21691-21696 . https://doi.org/10.1002/anie.202107221

مصطلحات موضوعية: antibody drug conjugate, atomic force microscopy, controlled DAR, DNA nanotechnology, protein conjugation

الاتاحة: https://pure.au.dk/portal/da/publications/a-wireframe-dna-cube(b7c9a41e-de01-4326-8147-9d83dba88f77).html
https://doi.org/10.1002/anie.202107221
http://www.scopus.com/inward/record.url?scp=85113978260&partnerID=8YFLogxK

المؤلفون: Märcher, Anders, Palmfeldt, Johan, Nisavic, Marija, Gothelf, Kurt Vesterager

المصدر: Märcher , A , Palmfeldt , J , Nisavic , M & Gothelf , K V 2021 , ' A Reagent for Amine-Directed Conjugation to IgG1 Antibodies ' , Angewandte Chemie International Edition , vol. 60 , no. 12 , pp. 6539-6544 . https://doi.org/10.1002/anie.202013911

مصطلحات موضوعية: IgG1, antibodies, fluorophore, labeling, site-direction

الاتاحة: https://pure.au.dk/portal/en/publications/3d28aca9-1f6c-4a95-bc56-881871627c84
https://doi.org/10.1002/anie.202013911
http://www.scopus.com/inward/record.url?scp=85100343789&partnerID=8YFLogxK

المؤلفون: Hansen, Rikke A., Märcher, Anders, Gothelf, Kurt V.

المصدر: Bioconjugate Chemistry; 10/19/2022, Vol. 33 Issue 10, p1811-1817, 7p

المؤلفون: Nielsen, Thorbjørn, Märcher, Anders, Drobňáková, Zuzana, Hučko, Michal, Štengl, Milan, Balšánek, Vojtěch, Wiberg, Charlotte, Nielsen, Per F., Nielsen, Thomas E., Gothelf, Kurt V., Cló, Emiliano

المصدر: Nielsen , T , Märcher , A , Drobňáková , Z , Hučko , M , Štengl , M , Balšánek , V , Wiberg , C , Nielsen , P F , Nielsen , T E , Gothelf , K V & Cló , E 2020 , ' Disulphide-mediated site-directed modification of proteins ' , Organic and Biomolecular Chemistry , vol. 18 , no. 25 , pp. 4717-4722 . https://doi.org/10.1039/d0ob00861c

الاتاحة: https://pure.au.dk/portal/en/publications/fd0ae506-7b58-4c53-a66c-17e7df3310c1
https://doi.org/10.1039/d0ob00861c
http://www.scopus.com/inward/record.url?scp=85087468923&partnerID=8YFLogxK

المؤلفون: Mortensen, Michael R., Skovsgaard, Mikkel B., Märcher, Anders, Andersen, Veronica L., Palmfeldt, Johan, Nielsen, Thorbjørn B., Tørring, Thomas, Laursen, Nick S., Andersen, Kasper R., Kjems, Jørgen, Gothelf, Kurt V.

المساهمون: Danmarks Grundforskningsfond, Novo Nordisk Fonden, Lundbeckfonden

المصدر: Bioconjugate Chemistry ; volume 31, issue 5, page 1295-1300 ; ISSN 1043-1802 1520-4812

الاتاحة: http://dx.doi.org/10.1021/acs.bioconjchem.0c00151
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.0c00151

المؤلفون: Liu, Tianqiang, Song, Ping, Märcher, Anders, Kjems, Jørgen, Yang, Chuanxu, Gothelf, Kurt Vesterager

المصدر: Liu , T , Song , P , Märcher , A , Kjems , J , Yang , C & Gothelf , K V 2019 , ' Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab‐DNA conjugates ' , ChemBioChem , vol. 20 , no. 8 , pp. 1014-1018 . https://doi.org/10.1002/cbic.201800685

مصطلحات موضوعية: EGFR cancer cells, antitumor agents, cetuximab–DNA conjugates, doxorubicin, drug delivery

الاتاحة: https://pure.au.dk/portal/da/publications/selective-delivery-of-doxorubicin-to-egfr-cancer-cells-by-cetuximabdna-conjugates(aab49d1b-6780-4584-87d5-2dcbab5eed30).html
https://doi.org/10.1002/cbic.201800685

المؤلفون: Märcher, Anders¹ (AUTHOR), Nijenhuis, Minke A. D.¹ (AUTHOR), Gothelf, Kurt V.¹ (AUTHOR) kvg@inano.au.dk

المصدر: Angewandte Chemie. 9/27/2021, Vol. 133 Issue 40, p21859-21864. 6p.

مصطلحات موضوعية: *DNA antibodies, *ATOMIC force microscopy, *TARGETED drug delivery, *DRUG utilization, *GEL electrophoresis, *TUBULINS

الشركة/الكيان: UNITED States. Food & Drug Administration

المؤلفون: Liu, Tianqiang, Song, Ping, Märcher, Anders, Kjems, Jørgen, Yang, Chuanxu, Gothelf, Kurt V.

المصدر: ChemBioChem; Apr2019, Vol. 20 Issue 8, p1014-1018, 5p