المؤلفون: Sarah, Letitia, Fujimori, Danica Galonić

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Cancer, Histone Demethylases, Histones, Jumonji Domain-Containing Histone Demethylases, Catalysis, Chromatin, Allosteric inhibitors, Domain crosstalk, Jumonji histone demethylases, Lysine demethylation, Orthosteric inhibitors, Post-translational modifications, Medicinal and Biomolecular Chemistry, Biophysics, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8tw6446g
https://escholarship.org/content/qt8tw6446g/qt8tw6446g.pdf

المؤلفون: Tingyu Fan, Jianlian Xie, Guo Huang, Lili Li, Xi Zeng, Qian Tao

المصدر: Epigenomes, Vol 8, Iss 3, p 36 (2024)

مصطلحات موضوعية: PHF8/KDM7B, epigenetics, lysine demethylation, malignant tumors, neurological diseases, Genetics, QH426-470, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2075-4655/8/3/36; https://doaj.org/toc/2075-4655

URL الوصول: https://doaj.org/article/2f819050c7d44badaf5e402f27e48f61

المؤلفون: Valerie Scott (9184755), Debasis Dey (3204858), Jordan Kuwik (11409260), Kathryn Hinkelman (11409263), Megan Waldman (11409266), Kabirul Islam (1999864)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Infectious Diseases, mammalian gene expression, like demethylase activity, length chromosomal histone, catalytic site renders, specific lysine demethylation, specific histone demethylase, specific chemical rescue, wild type dioxygenases, variant inactive toward, general application among, conserved phenylalanine residue, specific chemical probes, specific residue, successful application, enzyme toward, dependent dioxygenases, αkg derivatives, significant hurdle, remaining refractory, orthogonal enzyme, natural cosubstrate, human αkg, developing member

Relation: https://figshare.com/articles/journal_contribution/Allele-Specific_Chemical_Rescue_of_Histone_Demethylases_Using_Abiotic_Cofactors/16589990

الاتاحة: https://doi.org/10.1021/acschembio.1c00335.s001

المؤلفون: Samah W. Awwad, Nabieh Ayoub

المصدر: Biology Open, Vol 4, Iss 4, Pp 498-504 (2015)

مصطلحات موضوعية: DNA damage, KDM4 proteins, Mismatch repair, Chromosomal instability, Lysine demethylation, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://bio.biologists.org/content/4/4/498; https://doaj.org/toc/2046-6390

URL الوصول: https://doaj.org/article/9369613d41564d94850788e7dc32d36f

المؤلفون: Sylvain Lanouette, Vanessa Mongeon, Daniel Figeys, Jean‐François Couture

المصدر: Molecular Systems Biology, Vol 10, Iss 4, Pp 1-26 (2014)

مصطلحات موضوعية: lysine demethylation, lysine methylation, networks, proteomics, systems biology, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/3bde2bd8de554055bd9f038d74c6e7d8

المؤلفون: Ourailidou, Maria E., Lenoci, Alessia, Zwergel, Clemens, Rotili, Dante, Mai, Antonello, Dekker, Frank J

المصدر: Ourailidou , M E , Lenoci , A , Zwergel , C , Rotili , D , Mai , A & Dekker , F J 2017 , ' Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity ' , Bioorganic & Medicinal Chemistry , vol. 25 , no. 3 , pp. 847-856 . https://doi.org/10.1016/j.bmc.2016.11.043

مصطلحات موضوعية: Lysine demethylation, Tumorigenesis, Tranylcypromine, Irreversible inhibition, Enzyme labeling, LSD1 HISTONE DEMETHYLASE, OXIDATIVE HECK REACTION, THERAPEUTIC STRATEGY, BIOLOGICAL-ACTIVITY, STRUCTURAL BASIS, HDAC INHIBITORS, BREAST-CANCER, PROTEIN, CELLS, DERIVATIVES

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/15be3b25-f97c-4db5-be88-154df672f96d

الاتاحة: https://hdl.handle.net/11370/15be3b25-f97c-4db5-be88-154df672f96d
https://research.rug.nl/en/publications/15be3b25-f97c-4db5-be88-154df672f96d
https://doi.org/10.1016/j.bmc.2016.11.043
https://pure.rug.nl/ws/files/40292347/1_s2.0_S0968089616312640_main.pdf

المؤلفون: Tumber, A, Nuzzi, A, Hookway, ES, Hatch, SB, Velupillai, S, Johansson, C, Kawamura, A, Savitsky, P, Yapp, C, Szykowska, A, Wu, N, Bountra, C, Strain-Damerell, C, Burgess-Brown, NA, Ruda, GF, Fedorov, O, Munro, S, England, KS, Nowak, RP, Schofield, CJ, La Thangue, NB, Pawlyn, C, Davies, F, Morgan, G, Athanasou, N, Müller, S, Oppermann, U, Brennan, PE

المصدر: Cell Chemical Biology , 24 (3) pp. 371-380. (2017)

مصطلحات موضوعية: 2-oxoglutarate oxygenases, JARID1B, KDM5B, chromatin, demethylases, epigenetics, histones, lysine demethylation, myeloma, oncology

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1575168/1/Hookway_1-s2.0-S2451945617300363-main.pdf; https://discovery.ucl.ac.uk/id/eprint/1575168/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1575168/1/Hookway_1-s2.0-S2451945617300363-main.pdf
https://discovery.ucl.ac.uk/id/eprint/1575168/

المؤلفون: Min Wang, Bowei Chen, Shahid Ali, Xu Zhang, Linan Xie, Qingzhu Zhang, Yonglan Zhang

المصدر: BMC Genomics, Vol 22, Iss 1, Pp 1-19 (2021)
BMC Genomics

مصطلحات موضوعية: Jumonji Domain-Containing Histone Demethylases, QH426-470, Histone lysine demethylation, Histone demethylation, “Intracellular membrane”, Histone methylation, Genetics, Gene family, Epigenetics, Betula, Phylogeny, JmjC domains, Plant Proteins, Histone Demethylases, biology, Research, Birch, Low-temperature stress, Seed germination, Histone, biology.protein, Demethylase, BpJMJ genes, TP248.13-248.65, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d340a51496787ea0f34265bb7efde42e
https://doi.org/10.1186/s12864-021-08063-6

المؤلفون: Sachith Mettananda

المصدر: Frontiers in Genome Editing
Frontiers in Genome Editing, Vol 3 (2021)

مصطلحات موضوعية: Review, QH426-470, α-globin, Histone lysine demethylation, Genome editing, hemic and lymphatic diseases, medicine, Genetics, Genome Editing, Epigenetics, Enhancer, Vorinostat, Gene, CRISPR/Cas9, biology, α-thalassaemia, β-thalassaemia, Haemolysis, Histone, vorinostat, Cancer research, biology.protein, IOX1, TP248.13-248.65, medicine.drug, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d518753443ed0ae7fede01dfc015f799
https://pubmed.ncbi.nlm.nih.gov/34713267

المؤلفون: Lisheng Liu, Jiangnan Liu, Qinghai Lin

المصدر: Exp Ther Med

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, biology, Chemistry, Cellular differentiation, KDM2A, Review, General Medicine, Cell biology, 03 medical and health sciences, Histone lysine demethylation, 030104 developmental biology, 0302 clinical medicine, Histone, Immunology and Microbiology (miscellaneous), Ubiquitin, 030220 oncology & carcinogenesis, biology.protein, Phosphorylation, Demethylase, Epigenetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0377b2a2254f08b1973ac5c659791fe
https://doi.org/10.3892/etm.2021.10155

المؤلفون: Rajeev Ramanan, Tatyana G. Karabencheva-Christova, Christopher J. Schofield, Shobhit S. Chaturvedi, Christo Z. Christov, Nicolai Lehnert

المصدر: ACS Catalysis

مصطلحات موضوعية: 010405 organic chemistry, Stereochemistry, 2-oxoglutarate, non-heme iron enzyme, General Chemistry, Hydrogen atom, 010402 general chemistry, Hydrogen atom abstraction, 01 natural sciences, QM/MM, Catalysis, 0104 chemical sciences, histone lysine demethylation, chemistry.chemical_compound, Histone lysine demethylation, Molecular dynamics, chemistry, metal-center rearrangement, enzyme mechanism, Carboxylate, Demethylation, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a5de2cbd00f21f20e68f5b875fd018
https://pubmed.ncbi.nlm.nih.gov/31976154

المؤلفون: Pedro Crevillén

المصدر: iScience, Vol 23, Iss 11, Pp 101715-(2020)
iScience

مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, biology, fungi, Plant Biology, Plant Development, Review, 02 engineering and technology, Biological Sciences, 021001 nanoscience & nanotechnology, Cell biology, 03 medical and health sciences, Histone lysine demethylation, Histone H3, 030104 developmental biology, Histone, Gene expression, biology.protein, Gene silencing, lcsh:Q, Histone Demethylases, Epigenetics, 0210 nano-technology, Histone demethylase activity, lcsh:Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd774425a6ea5aaf704dbf41c6b1f081
http://www.sciencedirect.com/science/article/pii/S2589004220309123

المؤلفون: Feilong Wang, Lina Sun, Linyan Zhou, Wenjing Tao, Shuangyi Yang, Tian Gao, Deshou Wang, Zuliang Qin, Zhiqiang Li

المصدر: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 257:110674

مصطلحات موضوعية: Histone Demethylases, Male, Regulation of gene expression, Genetics, Subfamily, Sexual differentiation, Physiology, Cichlids, Biology, Biochemistry, Genome, Transcriptome, Histone lysine demethylation, Histone demethylation, Animals, Female, Gonads, Molecular Biology, Gene, In Situ Hybridization, Fluorescence, Phylogeny

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfe88abb9fca2e8a06cb1141b4a7128
https://doi.org/10.1016/j.cbpb.2021.110674

المؤلفون: Meilan Huang, Derek J. Quinn, Warispreet Singh, Thomas S. Moody

المصدر: Singh, W, Quinn, D, Moody, T & Huang, M 2019, ' Reaction Mechanism of Histone Demethylation in αKG-Dependent Non-Heme Iron Enzymes ', The Journal of Physical Chemistry B, vol. 123, no. 37, pp. 7801-7811 . https://doi.org/10.1021/acs.jpcb.9b06064

مصطلحات موضوعية: Reaction mechanism, 010402 general chemistry, complex mixtures, 01 natural sciences, Histones, Histone lysine demethylation, SDG 3 - Good Health and Well-being, Histone demethylation, 0103 physical sciences, Gene expression, Materials Chemistry, Humans, Non heme iron, Physical and Theoretical Chemistry, Enzyme Inhibitors, chemistry.chemical_classification, Histone Demethylases, Epigenetic Process, 010304 chemical physics, Chemistry, 0104 chemical sciences, Surfaces, Coatings and Films, Demethylation, Oxygen, Enzyme, Biochemistry, Biocatalysis, bacteria, Quantum Theory, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4458e2e336f7cb44a8e1b10c83f9bb
https://pubmed.ncbi.nlm.nih.gov/31469562

المؤلفون: Geovanny I. Nic-Can, Beatriz A. Rodas-Junco, Rafael Rojas-Herrera, Ricardo Peñaloza-Cuevas, Leydi Maribel Carrillo-Cocom, Fernando Javier Aguilar-Ayala, Alejandro Zepeda-Pedreguera

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3918 (2019)

مصطلحات موضوعية: Cellular differentiation, Review, Biology, Catalysis, Epigenesis, Genetic, lcsh:Chemistry, Inorganic Chemistry, Histones, Histone lysine demethylation, histone lysine demethylases, Histone methylation, Adipocytes, Animals, Humans, Epigenetics, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Histone Demethylases, mesenchymal stem cells, Adipogenesis, epigenetics, Organic Chemistry, Mesenchymal stem cell, General Medicine, Chromatin, Computer Science Applications, Cell biology, cell differentiation, Histone, lcsh:Biology (General), lcsh:QD1-999, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb71886884233cb76437ffa0bc48e223
http://europepmc.org/articles/PMC6719019

المؤلفون: Chaturvedi, Shobhit, Ramanan, Rajeev, Lehnert, Nicolai, Schofield, Christopher J, Karabencheva-Christova, Tatyana, Christov, Christo Z

المصدر: Michigan Tech Publications

مصطلحات موضوعية: histone lysine demethylation 2-oxoglutarate non-heme iron enzyme QM/MM metal-center rearrangement enzyme mechanism, Department of Chemistry, Chemistry

Relation: https://digitalcommons.mtu.edu/michigantech-p/1245; https://doi.org/10.1021/acscatal.9b04907

الاتاحة: https://digitalcommons.mtu.edu/michigantech-p/1245
https://doi.org/10.1021/acscatal.9b04907

المؤلفون: Xing Zhang, Xiaodong Cheng, Ruogu Hu, Antonello Mai, Ji Woong Han, Donatella Labella, Yanqi Chang, Young Sup Yoon, Anup K. Upadhyay, Dante Rotili

المصدر: Journal of Molecular Biology; Vol 416

مصطلحات موضوعية: Jumonji Domain-Containing Histone Demethylases, Histone H3 Lysine 4, bix analogs, enzymatic inhibition, epigenetics, histone lysine demethylation, Methyltransferase, Biology, Crystallography, X-Ray, Histone-Lysine N-Methyltransferase, Article, Histones, Mice, 03 medical and health sciences, Histone H3, Histone lysine demethylation, 0302 clinical medicine, Structural Biology, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Azepines, Fibroblasts, Protein Structure, Tertiary, 3. Good health, Histone, Biochemistry, 030220 oncology & carcinogenesis, Histone methyltransferase, Histone Methyltransferases, Quinazolines, biology.protein, Demethylase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61bb130809ed3bdf84f2aec5c229699
https://doi.org/10.1016/j.jmb.2011.12.036

المؤلفون: Toshihito Tanahashi, Sinji Kitamura, Naoki Muguruma, Tadahiko Nakagawa, Yasushi Sato, Koichi Okamoto, Tetsuji Takayama, Hiroshi Miyamoto

المصدر: Annals of Oncology. 30:v53

مصطلحات موضوعية: Cisplatin, business.industry, Cancer, Combination chemotherapy, Hematology, Drug resistance, medicine.disease, medicine.disease_cause, Histone lysine demethylation, Oncology, Docetaxel, medicine, Cancer research, Gene silencing, Carcinogenesis, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a6a3f485264bebd86383683906adb9a4
https://doi.org/10.1093/annonc/mdz239.077

المؤلفون: Molly Gale, Xiaodong Cheng, John R. Horton, Qin Yan

المصدر: DNA and Histone Methylation as Cancer Targets ISBN: 9783319597843

مصطلحات موضوعية: 0301 basic medicine, biology, Histone lysine methylation, Computational biology, 03 medical and health sciences, Histone lysine demethylation, 030104 developmental biology, 0302 clinical medicine, Histone, Histone demethylation, 030220 oncology & carcinogenesis, Histone methyltransferase, Histone H2A, biology.protein, Nucleosome, Epigenetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9330a3150d3f133ddced8436da0ec52a
https://doi.org/10.1007/978-3-319-59786-7_7

المؤلفون: Tumber, A, Nuzzi, A, Hookway, E, Hatch, S, Velupillai, S, Johansson, C, Kawamura, A, Savitsky, P, Yapp, C, Szykowska, A, Wu, N, Bountra, C, Strain-Damerell, C, Burgess-Brown, N, Ruda, G, Fedorov, O, Munro, S, England, K, Nowak, R, Schofield, C, La Thangue, N, Pawlyn, C, Davies, F, Morgan, G, Athanasou, N, Müller, S, Oppermann, U, Brennan, P

المصدر: Cell Chemical Biology

مصطلحات موضوعية: Niacinamide, Cell Survival, Pyridines, lysine demethylation, Glycine, Kaplan-Meier Estimate, Crystallography, X-Ray, Methylation, Article, Histones, Cell Line, Tumor, Humans, Protein Isoforms, 2-oxoglutarate oxygenases, Cell Proliferation, epigenetics, demethylases, Cell Cycle Checkpoints, JARID1B, myeloma, oncology, KDM5B, Ketoglutaric Acids, chromatin, Transcription Initiation Site, Multiple Myeloma, Retinoblastoma-Binding Protein 2, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f70e84b59d70a4818b842e8c20b10454
https://pubmed.ncbi.nlm.nih.gov/28262558