المؤلفون: Anjali Kumar, Amy McDonough, Roger B. Clark, Lyn Libertine, Greg LaRosa, Roger Rush, Daniel Elbaum, Diana Lamppu

المصدر: Journal of Medicinal Chemistry. 57:3966-3983

مصطلحات موضوعية: Male, Agonist, alpha7 Nicotinic Acetylcholine Receptor, medicine.drug_class, Anti-Inflammatory Agents, Inflammation, Pharmacology, PC12 Cells, Piperazines, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Nicotinic Agonists, Mice, Inbred BALB C, Chemistry, medicine.disease, In vitro, Rats, Bioavailability, Cellular infiltration, Piperazine, Biochemistry, Molecular Medicine, Signal transduction, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb08d7ccdd44e28b2851dbdbc7fd093
https://doi.org/10.1021/jm5004599

المؤلفون: Katherine Holton, Glenna Ford, Lyn Libertine, Kevin Fettes, Pamela Pavco, Lakshmipathi Pandarinathan, Shalesh Kaushal, Anastasia Khvorova, Sharon Shaw, Karen Bulock, Amanda Rodgers, Radouil Tzekov, Michael Byrne, William Stanney, Jennifer Lapierre, Yi Wang, James Cardia

المصدر: Journal of Ocular Pharmacology and Therapeutics. 29:855-864

مصطلحات موضوعية: Cell type, Small interfering RNA, Time Factors, Eye Diseases, Nanotechnology, Retinal Pigment Epithelium, Biology, Retina, Cell Line, Mice, chemistry.chemical_compound, RNA interference, In vivo, Animals, Humans, Distribution (pharmacology), Pharmacology (medical), RNA, Messenger, RNA, Small Interfering, Pharmacology, Retinal, In vitro, Cell biology, Mice, Inbred C57BL, Ophthalmology, chemistry, Duplex (building), Intravitreal Injections, RNA Interference, Rabbits, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28be102b1bf81c929deb5981201d9145
https://doi.org/10.1089/jop.2013.0148

المؤلفون: Michel Gillard, Alan J. Dipesa, Donna M. Wypij, Ralph Scannell, Lyn Libertine, Young Michelle, Timothy A. Lewis, Joseph Eckman, Lynn Bayless

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:1083-1085

مصطلحات موضوعية: Stereochemistry, Guinea Pigs, Clinical Biochemistry, Pharmaceutical Science, Hydroxamic Acids, Leukotriene B4, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Humans, Lipoxygenase Inhibitors, Molecular Biology, biology, Chemistry, Organic Chemistry, Histaminergic, Antagonist, In vitro, Blood, Enzyme inhibitor, Arachidonate 5-lipoxygenase, Histamine H1 Antagonists, biology.protein, Molecular Medicine, Pharmacophore, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6d105a9383e9187169f4a547641059
https://doi.org/10.1016/j.bmcl.2004.12.023

المؤلفون: Lyn Libertine, Diana Lampuu, Anjali Kumar, Greg Habgood, Dan Elbaum, Greg LaRosa, Alan Maziarz

المصدر: The FASEB Journal. 20

مصطلحات موضوعية: medicine.drug_class, Chemistry, Alpha (ethology), Pharmacology, Biochemistry, Anti-inflammatory, Carrageenan, chemistry.chemical_compound, Nicotinic agonist, Genetics, medicine, Molecular Biology, Biotechnology, Acetylcholine receptor, Paw edema

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9a4a4170928317a2787494822450bc34
https://doi.org/10.1096/fasebj.20.5.a1127-d

المؤلفون: Karen Wenberg, Doina Ene, Donna M. Wypij, Young Michelle, Lyn Libertine, Joseph Eckman, Timothy A. Lewis, Mark P. Arrington, Lynn Bayless, Bruce F. Wels, Ralph Scannell, James L. Ellis, Philippe Collart, Xiong Cai, Jean-Marie Nicolas

المصدر: Bioorganicmedicinal chemistry letters. 14(22)

مصطلحات موضوعية: Clinical Biochemistry, Guinea Pigs, Pharmaceutical Science, Loratadine, Pharmacology, Biochemistry, Histamine receptor, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Lipoxygenase Inhibitors, Molecular Biology, biology, Molecular Structure, Chemistry, Organic Chemistry, Antagonist, Biological activity, Zileuton, Histamine H1 Antagonists, Cetirizine, Rats, Enzyme inhibitor, Models, Animal, biology.protein, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e4120bb7d3e4e9701af66db03002d2
https://pubmed.ncbi.nlm.nih.gov/15482930

المؤلفون: Donna M. Wypij, Timothy A. Lewis, Bruce F. Wels, Ralph Scannell, Gurmit Grewal, James L. Ellis, Karen Wenberg, Lyn Libertine, Joseph Eckman, Lynn Bayless, Jean-Marie Nicolas

المصدر: Bioorganicmedicinal chemistry letters. 14(9)

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Histamine H1 receptor, Biochemistry, Drug Discovery, medicine, Animals, Humans, Lipoxygenase Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Organic Chemistry, Antagonist, Zileuton, Rats, Enzyme, chemistry, Enzyme inhibitor, Arachidonate 5-lipoxygenase, biology.protein, Histamine H1 Antagonists, Microsomes, Liver, Molecular Medicine, Pharmacophore, Caco-2 Cells, Receptor antagonist activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204e33980190324e742235787391b89c
https://pubmed.ncbi.nlm.nih.gov/15081022

المؤلفون: William M, Selig, Lynn, Bayless, Lyn, Libertine, Joseph B, Eckman, Donna M, Wypij, Bruce F, Wels, Maria, Eckert, Michelle A, Young, Jean M, Nicolas, Ralph T, Scannell, James L, Ellis

المصدر: Chest. 123

مصطلحات موضوعية: Disease Models, Animal, Arachidonate 5-Lipoxygenase, Bronchoconstriction, Guinea Pigs, Anti-Inflammatory Agents, Histamine Antagonists, Animals, Lipoxygenase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::41c33755d26ca6f6c7603eade584e05b
https://pubmed.ncbi.nlm.nih.gov/12628983

المؤلفون: Tesfaye Biftu, Changgeng Qian, Lyn Libertine-Garahan, Stephen Ip, Joseph Eckman, Tsung-Ying Shen, Tongchuan Li

المصدر: European journal of pharmacology. 250(3)

مصطلحات موضوعية: Agonist, Nicotine, medicine.drug_class, Pyridines, Pharmacology, Mecamylamine, Receptors, Nicotinic, Binding, Competitive, Cytisine, chemistry.chemical_compound, Bridged Bicyclo Compounds, Mice, Alkaloids, medicine, Animals, Drug Interactions, Acetylcholine receptor, Analgesics, Chemistry, Alkaloid, Brain, Bridged Bicyclo Compounds, Heterocyclic, Azocines, Rats, Nicotinic agonist, Epibatidine, Quinolizines, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e0fc36a9790b25aabb728f070e3d55
https://pubmed.ncbi.nlm.nih.gov/8112391

المؤلفون: Joanne Kamens, Anastasia Khvorova, Pamela Pavco, Amanda Rodgers, Glenna Ford, Karen Bulock, Bernice Smith-Anzures, Jennifer Lapierre, Jessica Lam, Lyn Libertine, Kehlen Flannery-Rossi, Jake Metterville, Michael Byrne, Michael Czech, Gary Ostroff

المصدر: The Journal of Immunology. 182:42.27-42.27

مصطلحات موضوعية: Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::31ba799d8460dead3c9df6af7b7f951b
https://doi.org/10.4049/jimmunol.182.supp.42.27

المؤلفون: Lyn Libertine, Jean M. Nicolas, James L. Ellis, William M. Selig, Ralph Scannell, Bruce F. Wels, Joseph Eckman, Lynn Bayless, Donna M. Wypij, Young Michelle, Maria Eckert

المصدر: Chest. 123:371S

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Leukotriene, biology, medicine.drug_class, business.industry, Antagonist, Pharmacology, Critical Care and Intensive Care Medicine, Receptor antagonist, Lipoxygenase, chemistry.chemical_compound, Mechanism of action, chemistry, Enzyme inhibitor, Arachidonate 5-lipoxygenase, biology.protein, medicine, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Histamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0046cd2e61b3ae90c110c0ccef2cb7cf
https://doi.org/10.1378/chest.123.3_suppl.371s