المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

المصدر: PLoS ONE, Vol 19, Iss 1, p e0296404 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/60a7b739d7944eaeb0107c707c4fa1d1

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/journal_contribution/S1_File_-/24963073

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.s001
https://figshare.com/articles/journal_contribution/S1_File_-/24963073

المؤلفون: Darren C. Holland (8479923), Dale W. Prebble (9682227), Safak Er (11979177), Joshua B. Hayton (11979180), Luke P. Robertson (4683901), Vicky M. Avery (115416), Andrii Domanskyi (10953667), Milton J. Kiefel (2230777), John N. A. Hooper (11979183), Anthony R. Carroll (2071573)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Cancer, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, psyn aggregate formation, numerous neurodegenerative diseases, new dibrominated β, future therapeutics aimed, aggregation (> 89, 3d7 parasite strain, prunolides could provide, 5 , prunolides (< b, (< b, cis <, 5 μm, known prunolides, weak activity, significantly inhibit, prunolide ’, plasmodium falciparum, parkinson ’, novel scaffold, first reported

Relation: https://figshare.com/articles/journal_contribution/_Synuclein_Aggregation_Inhibitory_Prunolides_and_a_Dibrominated_Carboline_Sulfamate_from_the_Ascidian_Synoicum_prunum/18799080

الاتاحة: https://doi.org/10.1021/acs.jnatprod.1c01172.s001

المؤلفون: Neda Safa (11841243), Tomaž Trobec (11841246), Darren C. Holland (8621991), Blazej Slazak (11841249), Erik Jacobsson (11341403), Jeffrey A. Hawkes (6947765), Robert Frangež (11841252), Kristina Sepčić (1840441), Ulf Göransson (1364202), Lindon W. K. Moodie (5052386), Luke P. Robertson (4683901)

مصطلحات موضوعية: Biochemistry, Pharmacology, Ecology, Immunology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, trifluoroacetic acid salts, show clear patterns, localized predominantly within, common ornamental poppy, papaver setiferum <, cholinesterase inhibitory drugs, two new 7, 1 , isolated natural products, orientale <, natural origin, inhibitory activities, vascular bundles, spatial distributions, spatial distribution, research program, reported instability, relative abundances, lower half, animal sources

Relation: https://figshare.com/articles/journal_contribution/Spatial_Distribution_and_Stability_of_Cholinesterase_Inhibitory_Protoberberine_Alkaloids_from_i_Papaver_setiferum_i_/17209152

الاتاحة: https://doi.org/10.1021/acs.jnatprod.1c00980.s001

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/figure/The_bioassay_guided_microfractionation_protocol_followed_for_the_identification_of_molecular_ions_in_sponge_extracts_exemplified_by_i_Erylus_i_sp_/24963079

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.g001
https://figshare.com/articles/figure/The_bioassay_guided_microfractionation_protocol_followed_for_the_identification_of_molecular_ions_in_sponge_extracts_exemplified_by_i_Erylus_i_sp_/24963079

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/figure/Structures_of_bromopyrrole_alkaloids_isolated_from_i_Stylissa_massa_i_/24963085

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.g003
https://figshare.com/articles/figure/Structures_of_bromopyrrole_alkaloids_isolated_from_i_Stylissa_massa_i_/24963085

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/dataset/Summary_of_the_antibacterial_activity_of_sponge_specimens_subjected_to_disc_diffusion_and_micro_dilution_assays_/24963091

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.t002
https://figshare.com/articles/dataset/Summary_of_the_antibacterial_activity_of_sponge_specimens_subjected_to_disc_diffusion_and_micro_dilution_assays_/24963091

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/figure/Schematic_diagram_of_the_strategy_used_in_marine_sponge_specimen_identification_and_compound_isolation_from_i_Stylissa_massa_i_/24963082

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.g002
https://figshare.com/articles/figure/Schematic_diagram_of_the_strategy_used_in_marine_sponge_specimen_identification_and_compound_isolation_from_i_Stylissa_massa_i_/24963082

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/dataset/Details_of_the_specimens_investigated_Species_identification_location_locality_name_and_coordinates_depth_of_collection_in_meters_voucher_museum_numbers_and_GenBank_accession_numbers_/24963088

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.t001
https://figshare.com/articles/dataset/Details_of_the_specimens_investigated_Species_identification_location_locality_name_and_coordinates_depth_of_collection_in_meters_voucher_museum_numbers_and_GenBank_accession_numbers_/24963088

المؤلفون: Lakmini Kosgahakumbura, Jayani Gamage, Luke P. Robertson, Taj Muhammad, Björn Hellman, Ulf Göransson, Prabath Jayasinghe, Chamari Hettiarachchi, Paco Cárdenas, Sunithi Gunasekera

مصطلحات موضوعية: Biochemistry, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sponge natural products, richest geographical locations, natural product literature, molecular ion peaks, exploration may lead, div >< p, extensive taxonomical study, stylissa massa <, escherichia coli <, aciculites orientalis <, seven promising species, three bromopyrrole alkaloids, potent antibacterial activity, staphylococcus aureus <, microfractionated organic extract, organic extract, bromopyrrole alkaloids, aureus <, current study, acanthella <, species ), 30 species, sri lanka

Relation: https://figshare.com/articles/dataset/Results_of_FMCA_against_the_histiocytic_human_lymphoma_cell_line_U-937_/24963094

الاتاحة: https://doi.org/10.1371/journal.pone.0296404.t003
https://figshare.com/articles/dataset/Results_of_FMCA_against_the_histiocytic_human_lymphoma_cell_line_U-937_/24963094

المؤلفون: Sanjeevan Rajendran, Luke P. Robertson, Lakmini Kosgahakumbura, Chathurika Fernando, Ulf Göransson, Helen Wang, Chamari Hettiarachchi, Sunithi Gunasekera

مصطلحات موضوعية: Pharmacology, Drug Discovery, General Medicine, Pharmacology and Toxicology, Farmakologi och toxikologi

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7218bc4e154ef8da29a002d878bb29
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501731

المؤلفون: Larissa Buedenbender, Luke P. Robertson, Leonardo Lucantoni, Vicky M. Avery, D. İpek Kurtböke, Anthony R. Carroll

المصدر: Marine Drugs; Volume 16; Issue 6; Pages: 189

مصطلحات موضوعية: actinomycetes, Streptomyces, ascidian-associated actinomycetes, Symplegma rubra, polyketide, ansamycin derivative, herbimycin, antiplasmodial activity

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/md16060189

الاتاحة: https://doi.org/10.3390/md16060189

المؤلفون: Vicky M. Avery, Anthony R. Carroll, Luke P. Robertson, Dale W Prebble, Darren C. Holland

المصدر: Organic Letters. 22:9574-9578

مصطلحات موضوعية: biology, Chemistry, Stereochemistry, Alkaloid, Organic Chemistry, Moderate activity, Plasmodium falciparum, Drug resistance, biology.organism_classification, Biochemistry, Absolute structure, Sponge, chemistry.chemical_compound, parasitic diseases, Physical and Theoretical Chemistry, Isoquinoline, Biological sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9276f2bd6d0a87864b61a00cdc6b81ea
https://doi.org/10.1021/acs.orglett.0c03633

المؤلفون: Darren C. Holland, Dale W. Prebble, Safak Er, Joshua B. Hayton, Luke P. Robertson, Vicky M. Avery, Andrii Domanskyi, Milton J. Kiefel, John N. A. Hooper, Anthony R. Carroll

المساهمون: Division of Pharmacology and Pharmacotherapy, Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Biosciences

مصطلحات موضوعية: Pharmacology, 119 Other natural sciences, RUBROLIDES, Organic Chemistry, CULTURES, Pharmaceutical Science, LEWY BODY, METABOLITES, Analytical Chemistry, Complementary and alternative medicine, 317 Pharmacy, FIBRILS, Drug Discovery, Molecular Medicine, CADIOLIDES

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681d6824f5e2603fe128de32b2198532
http://hdl.handle.net/10138/353211

المؤلفون: Darren C, Holland, Dale W, Prebble, Safak, Er, Joshua B, Hayton, Luke P, Robertson, Vicky M, Avery, Andrii, Domanskyi, Milton J, Kiefel, John N A, Hooper, Anthony R, Carroll

المصدر: Journal of natural products. 85(2)

مصطلحات موضوعية: Mice, Australia, alpha-Synuclein, Animals, Urochordata, Sulfonic Acids, Carbolines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::13f04a06261a243ace5a09d685bbf7da
https://pubmed.ncbi.nlm.nih.gov/35050597

المؤلفون: Neda Safa, Tomaž Trobec, Darren C. Holland, Blazej Slazak, Erik Jacobsson, Jeffrey A. Hawkes, Robert Frangež, Kristina Sepčić, Ulf Göransson, Lindon W. K. Moodie, Luke P. Robertson

مصطلحات موضوعية: Pharmacology, Organisk kemi, Complementary and alternative medicine, Drug Discovery, Organic Chemistry, Pharmaceutical Science, Molecular Medicine, Pharmacology and Toxicology, Farmakologi och toxikologi, Analytical Chemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ff027cbecfcbc27fc30878ef88711f
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-470533

المؤلفون: Neda, Safa, Tomaž, Trobec, Darren C, Holland, Blazej, Slazak, Erik, Jacobsson, Jeffrey A, Hawkes, Robert, Frangež, Kristina, Sepčić, Ulf, Göransson, Lindon W K, Moodie, Luke P, Robertson

المصدر: Journal of Natural Products

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Berberine Alkaloids, Animals, Humans, Cholinesterase Inhibitors, Papaver, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::26e5bb480ffd24cb8056563c905f9af5
https://pubmed.ncbi.nlm.nih.gov/34910498

المؤلفون: Alan L. Munn, Luke P. Robertson, Kathryn E. Rudolph, Anthony R. Carroll, Laurence K. Jennings

المصدر: Journal of Natural Products. 82:2620-2626

مصطلحات موضوعية: Pharmacology, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Pharmaceutical Science, Marine invertebrates, biology.organism_classification, 01 natural sciences, Yeast, 0104 chemical sciences, Analytical Chemistry, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Biochemistry, Drug Discovery, medicine, Molecular Medicine, Polycarpa, Procera, Guanabenz, Two-dimensional nuclear magnetic resonance spectroscopy, medicine.drug, EC50, Butenolide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::912bf74a085b554940f35fa8e318aa25
https://doi.org/10.1021/acs.jnatprod.9b00551

المؤلفون: Abigail V. Sharrock, Anthony R. Carroll, Paul A. Hume, Michael J. Page, Luke P. Robertson, Joe Bracegirdle, Robert A. Keyzers, David F. Ackerley

المصدر: Journal of Natural Products. 82:2000-2008

مصطلحات موضوعية: Pharmacology, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Pharmaceutical Science, biology.organism_classification, 01 natural sciences, Mass spectrometric, 0104 chemical sciences, Analytical Chemistry, Tunicate, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Drug Discovery, Botany, Molecular Medicine, Biological sciences, Didemnum

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::373f3af366a3342a2047014dc18087c9
https://doi.org/10.1021/acs.jnatprod.9b00493

المؤلفون: Vicky M. Avery, Luke P. Robertson, Anthony R. Carroll, Leonardo Lucantoni, Sandra Duffy

المصدر: Journal of Natural Products. 82:1019-1023

مصطلحات موضوعية: Pharmaceutical Science, Plant Roots, 01 natural sciences, Medicinal chemistry, Analytical Chemistry, chemistry.chemical_compound, Drug Discovery, Ic50 values, Moiety, Rutaceae, Biological sciences, Pharmacology, Xanthene, biology, 010405 organic chemistry, Organic Chemistry, Oxidation reduction, biology.organism_classification, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Xanthenes, Complementary and alternative medicine, chemistry, Molecular Medicine, Methanol, Oxidation-Reduction, Two-dimensional nuclear magnetic resonance spectroscopy, Acronychia pubescens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aef0dc9115004750c2292956d412dd4
https://doi.org/10.1021/acs.jnatprod.8b00956