المؤلفون: Frederic A. Meunier, Andreas Papadopulos, Michael J. Waters, Yash Chhabra, Birthe B. Kragelund, Ho Yi Wong, Helena Steinocher, Louise F. Nikolajsen, Kathryn A. Tunny, Aaron G. Smith, Andrew J. Brooks

المصدر: Oncogene
Chhabra, Y, Wong, H Y, Nikolajsen, L F, Steinocher, H, Papadopulos, A, Tunny, K A, Meunier, F A, Smith, A G, Kragelund, B B, Brooks, A J & Waters, M J 2018, ' A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation ', Oncogene, vol. 37, pp. 489-501 . https://doi.org/10.1038/onc.2017.352

مصطلحات موضوعية: Male, Threonine, 0301 basic medicine, Cancer Research, Lung Neoplasms, Magnetic Resonance Spectroscopy, Receptor expression, DNA Mutational Analysis, Suppressor of Cytokine Signaling Proteins, Growth hormone receptor, Cohort Studies, Mice, Phosphorylation, Receptor, Lung, SOCS2, Growth hormone secretion, Cell biology, Gene Expression Regulation, Neoplastic, Disease Progression, Original Article, Female, Protein Binding, Signal Transduction, medicine.medical_specialty, Cell signaling, Epithelial-Mesenchymal Transition, Proline, Ubiquitin-Protein Ligases, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Protein Domains, Cell Line, Tumor, Internal medicine, Journal Article, Genetics, medicine, Animals, Humans, Autocrine signalling, Molecular Biology, Ubiquitination, Computational Biology, Cancer, medicine.disease, HEK293 Cells, 030104 developmental biology, Endocrinology, Proteolysis, Carrier Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a81d5f9d47c1a41e18529c63aa687af
https://doi.org/10.1038/onc.2017.352

المؤلفون: Andrew J. Brooks, Daniel Abankwa, Yash Chhabra, Alan E. Mark, Megan L. O'Mara, Yann Gambin, Wei Dai, Guillermo A. Gomez, Louise F. Nikolajsen, Michael W. Parker, Manolis Doxastakis, Michael J. Waters, Emma Sierecki, Gitte W. Haxholm, Kathryn A. Tunny

المصدر: Biophysical Journal. 110(3)

مصطلحات موضوعية: Biochemistry, Growth-hormone-releasing hormone receptor, Growth factor receptor, ROR1, Enzyme-linked receptor, Biophysics, 5-HT5A receptor, Growth hormone receptor, Biology, Interleukin-13 receptor, Insulin-like growth factor 1 receptor, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00532d5b9f83fdbc979eccebe21c4f3

المؤلفون: Suwen Zhao, Raymond C. Stevens, Walden E. Bjørn-Yoshimoto, Lu Qu, Xi Ping Huang, Jianjun Cheng, Vsevolod Katritch, Kang Ding, Michael A. Hanson, Zhi-Jie Liu, Anders A. Jensen, Petr Popov, Yao Peng, Mengchen Pu, Ling Shen, Daniel Wacker, Louise F. Nikolajsen, John D. McCorvy, Shuguang Yuan, Gye Won Han, Tao Che, Katherine Lansu, David E. Gloriam, Bryan L. Roth, Kasper Harpsøe, Yiran Wu

المصدر: Cell. 172:719-730.e14

مصطلحات موضوعية: 0301 basic medicine, Agonist, Drug discovery, medicine.drug_class, Ritanserin, Computational biology, Biology, General Biochemistry, Genetics and Molecular Biology, 5-HT2C receptor, 03 medical and health sciences, 030104 developmental biology, medicine, Functional selectivity, Inverse agonist, Receptor, G protein-coupled receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::418cf9a8ea70063f82dd0b1e4db975b9
https://doi.org/10.1016/j.cell.2018.01.001

المؤلفون: Helena Steinocher, Andrew J. Brooks, Kresten Lindorff-Larsen, Birthe B. Kragelund, Katrine Bugge, Louise F. Nikolajsen

المصدر: Biophysical Journal. 112:171a

مصطلحات موضوعية: Chemistry, Biophysics, Growth hormone receptor, Cell membrane, stomatognathic diseases, Transmembrane domain, medicine.anatomical_structure, Biochemistry, Helix, Extracellular, medicine, Binding site, Receptor, Janus kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8f14b96b36004e2c109f0420aaedb707
https://doi.org/10.1016/j.bpj.2016.11.947

المؤلفون: Michael A. Hanson, David E. Gloriam, Eshita Mutt, Vignir Isberg, Raymond C. Stevens, Janne M. Bibbe, Tilman Flock, Xavier Deupi, Louise F. Nikolajsen, Christian Munk

المصدر: Nature Methods

مصطلحات موضوعية: Rhodopsin, Glycosylation, Computer science, Allosteric regulation, Computational biology, Drug action, Crystallography, X-Ray, Protein Engineering, Biochemistry, Article, Receptors, G-Protein-Coupled, 03 medical and health sciences, Resource (project management), Protein Domains, Animals, Humans, Phosphorylation, Databases, Protein, Molecular Biology, 030304 developmental biology, G protein-coupled receptor, Structure (mathematical logic), Internet, 0303 health sciences, Cryoelectron Microscopy, Computational Biology, Cell Biology, HEK293 Cells, Drug Design, Mutation, Cattle, Receptor activation, Allosteric Site, Software, Signal Transduction, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bc97a92d212b2ae59ae6d81c34818b