المؤلفون: Stamatia Papoutsopoulou, Michael D. Burkitt, François Bergey, Hazel England, Rachael Hough, Lorraine Schmidt, David G. Spiller, Michael H. R. White, Pawel Paszek, Dean A. Jackson, Vitor A. P. Martins Dos Santos, Gernot Sellge, D. Mark Pritchard, Barry J. Campbell, Werner Müller, Chris S. Probert

المصدر: Frontiers in Immunology, Vol 10 (2019)

مصطلحات موضوعية: inflammatory bowel disease, NF-κB, macrophages, cytokines, Crohn's disease, ulcerative colitis, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.02168/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/d581931c5d434a78a70223703dfa1143

المؤلفون: Antony Adamson, Christopher Boddington, Polly Downton, William Rowe, James Bagnall, Connie Lam, Apolinar Maya-Mendoza, Lorraine Schmidt, Claire V. Harper, David G. Spiller, David A. Rand, Dean A. Jackson, Michael R. H. White, Pawel Paszek

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1d4f418033bb45d7b771ae8b6ba8118e

المؤلفون: Michael R. H. White, Pawel Paszek, Christopher Boddington, Lorraine Schmidt, James Boyd, Zainab Alsoufi, James Bagnall, Ronan O’Cualain, David G. Spiller, Werner Müller, Dean A. Jackson, Polly Downton, Hazel England, Nisha M. X. Patel, Alex Bennett, Antony Adamson, William Rowe, Mark Muldoon, Ruth Brignall, Catherine Walker

المصدر: Bagnall, J, Boddington, C, England, H, Brignall, R, Downton, P, Alsoufi, Z, Boyd, J, Rowe, W, Bennett, A, Walker, C, Adamson, A, Patel, N, O'Cualain, R, Schmidt, L, Spiller, D, Jackson, D, Muller, W, Muldoon, M, White, M & Paszek, P 2018, ' Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation ', Science Signaling, vol. 11, no. 540, eaaf3998 . https://doi.org/10.1126/scisignal.aaf3998

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Mice, Transgenic, Biochemistry, Proinflammatory cytokine, competitive uptake, Mice, 03 medical and health sciences, Single-cell analysis, macrophage activation, cellular heterogeneity, medicine, Animals, Humans, Molecular Biology, tissue-level regulation, Cells, Cultured, Inflammation, Toll-like receptor, Tumor Necrosis Factor-alpha, Chemistry, Macrophages, HEK 293 cells, NF-kappa B, NF-kappa B p50 Subunit, Cell Biology, Macrophage Activation, Cell biology, Toll-Like Receptor 4, HEK293 Cells, RAW 264.7 Cells, 030104 developmental biology, Cytokine, Immunology, TLR4, toll-like receptor, Tumor necrosis factor alpha, Single-Cell Analysis, Signal transduction, Signal Transduction

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6ecc759bca55be0a974323a0affaca
https://doi.org/10.1126/scisignal.aaf3998

المؤلفون: Antony Adamson, William Rowe, Simon West, Claire V. Harper, Michael R. H. White, Connie Lam, David A. Rand, Louise Ashall, Lorraine Schmidt, Polly Downton, Manuel Garcia-Albornoz, Dan J. Woodcock, David G. Spiller

المصدر: Harper, C V, Woodcock, D J, Lam, C, Garcia-Albornoz, M, Adamson, A, Ashall, L, Rowe, W, Downton, P, Schmidt, L, West, S, Spiller, D G, Rand, D A & White, M R H 2018, ' Temperature regulates NF-κB dynamics and function through timing of A20 transcription ', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 22, pp. E5243-E5249 . https://doi.org/10.1073/pnas.1803609115
Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, NF-κB, 03 medical and health sciences, chemistry.chemical_compound, Mice, Transcription (biology), Cell Line, Tumor, Gene silencing, Animals, Humans, QH426, Cells, Cultured, Tumor Necrosis Factor alpha-Induced Protein 3, Regulation of gene expression, Inflammation, Multidisciplinary, Tumor Necrosis Factor-alpha, Systems Biology, NF-kappa B, Temperature, dynamics, Biological Sciences, NFKB1, Cell biology, Dynamics, 030104 developmental biology, A20, chemistry, Gene Expression Regulation, PNAS Plus, Gene Knockdown Techniques, Cytokines, Tumor necrosis factor alpha, Signal transduction, RB, transcription, Transcription, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d32f0dc16e310babd93e5c64efb9af
https://doi.org/10.1073/pnas.1803609115

المؤلفون: Stamatia Papoutsopoulou, Michael D. Burkitt, François Bergey, Hazel England, Rachael Hough, Lorraine Schmidt, David G. Spiller, Michael H. R. White, Pawel Paszek, Dean A. Jackson, Vitor A. P. Martins Dos Santos, Gernot Sellge, D. Mark Pritchard, Barry J. Campbell, Werner Müller, Chris S. Probert

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, inflammatory bowel disease, NF-κB, macrophages, cytokines, Crohn's disease, ulcerative colitis

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Macrophage-Specific_NF-_B_Activation_Dynamics_Can_Segregate_Inflammatory_Bowel_Disease_Patients_PDF/9804776

الاتاحة: https://doi.org/10.3389/fimmu.2019.02168.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Macrophage-Specific_NF-_B_Activation_Dynamics_Can_Segregate_Inflammatory_Bowel_Disease_Patients_PDF/9804776

المؤلفون: Christopher Boddington, Michael R. H. White, Nicholas Jones, William Rowe, Pawel Paszek, Lorraine Schmidt, James Boyd, Ruth Brignall, David G. Spiller, James Bagnall

المصدر: Integrative biology : quantitative biosciences from nano to macro. 7(6)

مصطلحات موضوعية: Cell signaling, Transgene, Biophysics, Biology, Biochemistry, Jurkat cells, Time-Lapse Imaging, Cell Line, 03 medical and health sciences, Immune System Phenomena, Jurkat Cells, Mice, 0302 clinical medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, Microscopy, Confocal, NFATC Transcription Factors, HEK 293 cells, Lentivirus, Gene Transfer Techniques, Models, Immunological, Transcription Factor RelA, NFAT, NFKB1, Fusion protein, Cell biology, STAT Transcription Factors, HEK293 Cells, RAW 264.7 Cells, Immune System, STAT protein, Single-Cell Analysis, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b794ddcb1ecce9f45e8eddc49cac3a64
https://pubmed.ncbi.nlm.nih.gov/25990200

المؤلفون: Emmanuel, Pinteaux, Wataru, Inoue, Lorraine, Schmidt, Francisco, Molina-Holgado, Nancy J, Rothwell, Giamal N, Luheshi

المصدر: Journal of neurochemistry. 102(3)

مصطلحات موضوعية: Leptin, Lipopolysaccharides, STAT3 Transcription Factor, Caspase 1, Interleukin-1beta, Brain, Receptors, Cell Surface, Caspase Inhibitors, Coculture Techniques, Rats, Rats, Sprague-Dawley, Interleukin 1 Receptor Antagonist Protein, Animals, Newborn, Animals, Encephalitis, Receptors, Leptin, Microglia, RNA, Messenger, Enzyme Inhibitors, Inflammation Mediators, Cells, Cultured, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5243c72a2b2fc51ce620610608e5dc42
https://pubmed.ncbi.nlm.nih.gov/17419800