المؤلفون: Paul Baverel, Lorin Roskos, Manasa Tatipalli, Nancy Lee, Paul Stockman, Maria Taboada, Paolo Vicini, Kevin Horgan, Rajesh Narwal

المصدر: Clinical and Translational Science, Vol 12, Iss 5, Pp 450-458 (2019)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

URL الوصول: https://doaj.org/article/b6d5b1ddac5644ac85fd3fb4531ab7e3

المؤلفون: Hanwen Wang, Oleg Milberg, Imke H. Bartelink, Paolo Vicini, Bing Wang, Rajesh Narwal, Lorin Roskos, Cesar A. Santa-Maria, Aleksander S. Popel

المصدر: Royal Society Open Science, Vol 6, Iss 5 (2019)

مصطلحات موضوعية: immuno-oncology, immune checkpoint inhibitor, computational model, systems biology, computational biology, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2054-5703

URL الوصول: https://doaj.org/article/572016b0fdc645a1b9f505b6ab696d63

المؤلفون: Benjamin Duy Tran, Jing Li, Neang Ly, Raffaella Faggioni, Lorin Roskos

المصدر: Cancer Chemotherapy and Pharmacology. 91:179-189

مصطلحات موضوعية: Pharmacology, Cancer Research, Oncology, Pharmacology (medical), Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::921346d04baa2d2d87d218612a776fb9
https://doi.org/10.1007/s00280-022-04500-9

المؤلفون: Ting Chen, Yanan Zheng, Lorin Roskos, Donald E. Mager

المصدر: Journal of Pharmacokinetics and Pharmacodynamics.

مصطلحات موضوعية: Pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e2afa651f5ff66c5b79a0b650ddb63ae
https://doi.org/10.1007/s10928-023-09848-w

المؤلفون: Hanwen Wang, Oleg Milberg, Imke H. Bartelink, Paolo Vicini, Bing Wang, Rajesh Narwal, Lorin Roskos, Cesar A. Santa-Maria, Aleksander S. Popel

مصطلحات موضوعية: Systems Biology, Computational Biology, immuno-oncology, immune checkpoint inhibitor, computational model

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Material_from_i_In_silico_i_simulation_of_a_clinical_trial_with_anti-CTLA-4_and_anti-PD-L1_immunotherapies_in_metastatic_breast_cancer_using_a_systems_pharmacology_model/8094311

الاتاحة: https://doi.org/10.6084/m9.figshare.8094311.v2
https://figshare.com/articles/journal_contribution/Supplementary_Material_from_i_In_silico_i_simulation_of_a_clinical_trial_with_anti-CTLA-4_and_anti-PD-L1_immunotherapies_in_metastatic_breast_cancer_using_a_systems_pharmacology_model/8094311

المؤلفون: Chang Gong, Oleg Milberg, Bing Wang, Paolo Vicini, Rajesh Narwal, Lorin Roskos, Aleksander S. Popel

مصطلحات موضوعية: Computational Biology, Systems Biology, immuno-oncology, immunotherapy, immune checkpoint, biomarker

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Information_from_A_computational_multiscale_agent-based_model_for_simulating_spatio-temporal_tumour_immune_response_to_PD1_and_PDL1_inhibition/5394583

الاتاحة: https://doi.org/10.6084/m9.figshare.5394583.v2
https://figshare.com/articles/journal_contribution/Supplementary_Information_from_A_computational_multiscale_agent-based_model_for_simulating_spatio-temporal_tumour_immune_response_to_PD1_and_PDL1_inhibition/5394583

المؤلفون: Raj Tummala, Shiliang Wang, Lorin Roskos, Bing Wang, Linda Santiago, Denison Kuruvilla, Yen Lin Chia

المصدر: Rheumatology. 60:5854-5862

مصطلحات موضوعية: Adult, Male, Drug, Oncology, medicine.medical_specialty, media_common.quotation_subject, Population, Alpha interferon, Receptor, Interferon alpha-beta, Antibodies, Monoclonal, Humanized, Placebo, 030226 pharmacology & pharmacy, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rheumatology, Pharmacokinetics, Internal medicine, medicine, Humans, Lupus Erythematosus, Systemic, Pharmacology (medical), Lead (electronics), education, Aged, media_common, 030203 arthritis & rheumatology, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Middle Aged, Confidence interval, Regimen, Treatment Outcome, Female, business, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962edd9d56d3ed2cd033aae87af98080
https://doi.org/10.1093/rheumatology/keab176

المؤلفون: Joachim Almquist, Denison Kuruvilla, Tu Mai, Raj Tummala, Wendy I. White, Weifeng Tang, Lorin Roskos, Yen Lin Chia

المصدر: Journal of clinical pharmacology. 62(9)

مصطلحات موضوعية: Pharmacology, Humans, Lupus Erythematosus, Systemic, Pharmacology (medical), Administration, Intravenous, Antibodies, Monoclonal, Humanized, Healthy Volunteers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9a68d93ef6e428c3233f97cca0ca03
https://pubmed.ncbi.nlm.nih.gov/35383948

المؤلفون: Alison Scott, Alan N. Hunt, Dominic J. Corkill, Nicholas J. White, Patricia C. Ryan, Anthony D. Postle, Lorin Roskos, Marlon Rebelatto, Mary Jane Hinrichs, Matthew J Robinson, Josquin A Nys, Matthew Sleeman

مصطلحات موضوعية: medicine.medical_specialty, Pharmacology, Pulmonary Alveolar Proteinosis, Antibodies, Monoclonal, Humanized, Choline, Arthritis, Rheumatoid, Mice, Surface-Active Agents, Blocking antibody, medicine, Animals, Receptor, Autoantibodies, Inflammation, Mice, Knockout, Lung, business.industry, Interleukin-6, SARS-CoV-2, Autoantibody, COVID-19, Granulocyte-Macrophage Colony-Stimulating Factor, Pulmonary Surfactants, General Medicine, medicine.disease, Mice, Inbred C57BL, medicine.anatomical_structure, Granulocyte macrophage colony-stimulating factor, Phenotype, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Alveolar macrophage, Histopathology, Female, business, Pulmonary alveolar proteinosis, Bronchoalveolar Lavage Fluid, medicine.drug

وصف الملف: text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f387d3995ba16db8e7128ba41dea8042
https://eprints.soton.ac.uk/452362/

المؤلفون: Alexandra Drakaki, Michael S. Gordon, Shaad Essa Abdullah, Wenmei Huang, Michael Ong, Jingsong Zhang, Natasha Angra, Pralay Mukhopadhyay, Xiang Guo, Arnold Degboe, Srikala S. Sridhar, Ashok K. Gupta, Alexander I. Spira, Hendrick Tobias Arkenau, Terence W. Friedlander, Peter H. O'Donnell, Lorin Roskos

المصدر: Cancer. 126:432-443

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Metastatic Urothelial Carcinoma, Bladder cancer, Durvalumab, business.industry, Locally advanced, Cancer, medicine.disease, Inflammatory biomarkers, humanities, 03 medical and health sciences, 0302 clinical medicine, Quality of life, 030220 oncology & carcinogenesis, Internal medicine, medicine, In patient, 030212 general & internal medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::12fbe85d31acd7158f02845553ce089c
https://doi.org/10.1002/cncr.32532

المؤلفون: Maria Taboada, Nancy Lee, Paolo Vicini, Lorin Roskos, Rajesh Narwal, Manasa Tatipalli, Kevin Horgan, Paul Baverel, Paul K. Stockman

المصدر: Clinical and Translational Science, Vol 12, Iss 5, Pp 450-458 (2019)
Clinical and Translational Science

مصطلحات موضوعية: Mesothelioma, Oncology, medicine.medical_specialty, Lung Neoplasms, Population, Kaplan-Meier Estimate, Antibodies, Monoclonal, Humanized, Models, Biological, Article, General Biochemistry, Genetics and Molecular Biology, law.invention, Randomized controlled trial, Pharmacokinetics, Risk Factors, law, Internal medicine, medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, education, education.field_of_study, business.industry, Research, General Neuroscience, lcsh:Public aspects of medicine, Mesothelioma, Malignant, Confounding, lcsh:RM1-950, Confounding Factors, Epidemiologic, lcsh:RA1-1270, Articles, General Medicine, medicine.disease, lcsh:Therapeutics. Pharmacology, Quartile, Monoclonal, business, Tremelimumab, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b01a2b38a68836cb0f24484c3ac4d09
https://doaj.org/article/b6d5b1ddac5644ac85fd3fb4531ab7e3

المؤلفون: Lorin Roskos, Binbing Yu, Rajesh Narwal, Terrance O'Day, Judith Anderton, Gareth M. Davies, Gina DAngelo, Jay Harper, Wei Zhao, Steven Novick, Paolo Vicini, Harry Yang

المصدر: Pharmaceutical Statistics. 18:688-699

مصطلحات موضوعية: Statistics and Probability, Combination therapy, medicine.medical_treatment, Computational biology, 01 natural sciences, 010104 statistics & probability, 03 medical and health sciences, 0302 clinical medicine, In vivo, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Drug Interactions, Pharmacology (medical), Tumor growth, 030212 general & internal medicine, 0101 mathematics, Pharmacology, Kinetic model, Chemistry, Linear model, Tumor kinetics, Drug Synergism, Immunotherapy, Models, Theoretical, Regression, Kinetics, Treatment Outcome, Linear Models

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703dcd0e80ac35cc93d91eee6f60df64
https://doi.org/10.1002/pst.1952

المؤلفون: Mitchell Goldman, Binbing Yu, Lorin Roskos, Li Yan, Yen Lin Chia, Peter Barker, Bing Wang

المصدر: Clinical Pharmacology and Therapeutics

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Population, Placebo, Antibodies, Monoclonal, Humanized, 030226 pharmacology & pharmacy, Gastroenterology, Severity of Illness Index, Article, 03 medical and health sciences, chemistry.chemical_compound, Leukocyte Count, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Forced Expiratory Volume, Severity of illness, medicine, Humans, Pharmacology (medical), Anti-Asthmatic Agents, education, Aged, Pharmacology, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Research, Articles, Eosinophil, Benralizumab, Symptom Flare Up, Asthma, Eosinophils, Dose–response relationship, medicine.anatomical_structure, Outcome and Process Assessment, Health Care, chemistry, Quartile, 030220 oncology & carcinogenesis, Female, Drug Monitoring, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42379c176f0f57a46e5767d9e5a97af
http://europepmc.org/articles/PMC6767326

المؤلفون: Lorin Roskos, Alejandro Javier Yovine, Rosalinda Hgp Arends, Nassim Morsli, Ignacio González-García, Xiang Guo, James Xie, Paul Baverel

المصدر: Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Durvalumab, Protein biomarkers, durvalumab, medicine.drug_class, overall survival, Immune checkpoint inhibitors, Immunology, immune checkpoint inhibitor, head and neck squamous cell carcinoma, Monoclonal antibody, 03 medical and health sciences, 0302 clinical medicine, Overall survival, Humans, Immunology and Allergy, Medicine, RC254-282, Original Research, Squamous Cell Carcinoma of Head and Neck, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Antibodies, Monoclonal, Biomarker, RC581-607, medicine.disease, Head and neck squamous-cell carcinoma, stomatognathic diseases, 030104 developmental biology, Oncology, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Cancer research, Biomarker (medicine), Immunologic diseases. Allergy, business, Biomarkers, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ccf7a3a09f69f3e47187c3a39881e6
https://doi.org/10.1080/2162402x.2021.1898104

المؤلفون: Inna Vainshtein, Lorin Roskos, Amy Schneider, Bing Wang, Meina Liang

المصدر: The AAPS Journal. 23

مصطلحات موضوعية: biology, medicine.diagnostic_test, Chemistry, Platelet-Derived Growth Factor Receptor Alpha, media_common.quotation_subject, Pharmaceutical Science, Ligand (biochemistry), 030226 pharmacology & pharmacy, Cell biology, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Growth factor receptor, 030220 oncology & carcinogenesis, biology.protein, medicine, Signal transduction, Internalization, Receptor, Platelet-derived growth factor receptor, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::358810af3e759cfba9c38c65a3b4b622
https://doi.org/10.1208/s12248-020-00523-3

المؤلفون: Lorin Roskos, Neang Ly, Yanan Zheng, Jane R. Parnes, Janet M. Griffiths, Rene van der Merwe, Balaji Agoram

المصدر: Journal of clinical pharmacologyReferences. 61(7)

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Thymic stromal lymphopoietin, Adolescent, Metabolic Clearance Rate, medicine.medical_treatment, Population, Antibodies, Monoclonal, Humanized, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Sex Factors, Pharmacokinetics, Thymic Stromal Lymphopoietin, Internal medicine, Medicine, Humans, Pharmacology (medical), Dosing, Anti-Asthmatic Agents, education, Child, Asthma, Pharmacology, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Body Weight, Age Factors, Patient Acuity, medicine.disease, Respiratory Function Tests, Cytokine, 030220 oncology & carcinogenesis, Pharmacodynamics, Exhaled nitric oxide, Cytokines, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae232e20b612adfec02c979a6dd966a
https://pubmed.ncbi.nlm.nih.gov/33368307

المؤلفون: Meina Liang, Natalie J. Tigue, Lorin Roskos, Raffaella Faggioni, Jackie Cheng, Miguel F. Carvalho, Inna Vainshtein

المصدر: Antibodies
Volume 9
Issue 3
Antibodies, Vol 9, Iss 49, p 49 (2020)

مصطلحات موضوعية: 0301 basic medicine, lcsh:Immunologic diseases. Allergy, intracellular trafficking, media_common.quotation_subject, Immunology, Endocytic cycle, education, Protein degradation, bispecific, Endocytosis, Receptor tyrosine kinase, Epitope, Article, 03 medical and health sciences, 0302 clinical medicine, HER2, Drug Discovery, medicine, Immunology and Allergy, Receptor, Internalization, skin and connective tissue diseases, neoplasms, media_common, antibody internalization, biology, Chemistry, biparatopic antibody, Cell biology, 030104 developmental biology, Mechanism of action, 030220 oncology & carcinogenesis, biology.protein, protein degradation, medicine.symptom, lcsh:RC581-607

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f64fe28760bee436408bcfd2387293

المؤلفون: Meina, Liang, Bing, Wang, Amy, Schneider, Inna, Vainshtein, Lorin, Roskos

المصدر: The AAPS journal. 23(1)

مصطلحات موضوعية: Platelet-Derived Growth Factor, Receptor, Platelet-Derived Growth Factor alpha, Drug Evaluation, Preclinical, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antibodies, Neutralizing, Models, Biological, Biomarkers, Pharmacological, Macaca fascicularis, Mice, Cell Line, Tumor, Neoplasms, Animals, Humans, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::40516ba86e408e6f00a56f2b8a7bf251
https://pubmed.ncbi.nlm.nih.gov/33210183

المؤلفون: Patricia C. Ryan, D. Close, Shiliang Wang, A. Godwood, Xiang Guo, Wendy I. White, Lorin Roskos

المصدر: International Journal of Rheumatic Diseases

مصطلحات موضوعية: Oncology, rheumatoid arthritis, Male, Proteomics, Time Factors, TNF, Biomarkers, Pharmacological, Arthritis, Rheumatoid, 0302 clinical medicine, Mavrilimumab, biological therapies, Medicine, 030212 general & internal medicine, media_common, biology, GM‐CSF, Interleukin, Antibodies, Monoclonal, Middle Aged, Treatment Outcome, Rheumatoid arthritis, Antirheumatic Agents, Tumor necrosis factor alpha, Original Article, Female, Antibody, Drug Monitoring, Inflammation Mediators, medicine.drug, Drug, Adult, Genetic Markers, medicine.medical_specialty, media_common.quotation_subject, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, Rheumatology, Double-Blind Method, Internal medicine, Humans, 030203 arthritis & rheumatology, business.industry, Tumor Necrosis Factor-alpha, Gene Expression Profiling, biomarkers, Granulocyte-Macrophage Colony-Stimulating Factor, Original Articles, medicine.disease, Golimumab, Pharmacodynamics, biology.protein, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfe08fbd79e144e6a1b185208b1bcbd
http://europepmc.org/articles/PMC6587493

المؤلفون: Harry Yang, Kris Sachsenmeier, Lorin Roskos, Steven Novick, Ching Ching Leow

المصدر: Statistics in Biopharmaceutical Research. 10:151-157

مصطلحات موضوعية: Statistics and Probability, Oncology, medicine.medical_specialty, business.industry, Bayesian probability, Pharmaceutical Science, 01 natural sciences, 010104 statistics & probability, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Internal medicine, medicine, 0101 mathematics, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3bf7e1bc586c79dad92944d35cc82586
https://doi.org/10.1080/19466315.2018.1424649