المؤلفون: Corti, Giorgio, Buzo, Kristi, Berrino, Enrico, Miotto, Martina, Aquilano, Maria Costanza, Lentini, Marilena, Bellomo, Sara Erika, Lorenzato, Annalisa, Bartolini, Alice, Mauri, Gianluca, Lazzari, Luca, Russo, Mariangela, Di Nicolantonio, Federica, Siena, Salvatore, Marsoni, Silvia, Marchiò, Caterina, Bardelli, Alberto, Arena, Sabrina

المساهمون: G. Corti, K. Buzo, E. Berrino, M. Miotto, M.C. Aquilano, M. Lentini, S.E. Bellomo, A. Lorenzato, A. Bartolini, G. Mauri, L. Lazzari, M. Russo, F. Di Nicolantonio, S. Siena, S. Marsoni, C. Marchiò, A. Bardelli, S. Arena

مصطلحات موضوعية: Settore MEDS-09/A - Oncologia medica

Relation: info:eu-repo/semantics/altIdentifier/pmid/39402170; info:eu-repo/semantics/altIdentifier/wos/WOS:001331225700002; volume:8; issue:1; firstpage:1; lastpage:9; numberofpages:9; journal:NPJ PRECISION ONCOLOGY; https://hdl.handle.net/2434/1113149

الاتاحة: https://hdl.handle.net/2434/1113149
https://doi.org/10.1038/s41698-024-00706-7

المؤلفون: Sogari, Alberto, Rovera, Emanuele, Grasso, Gaia, Mariella, Elisa, Reilly, Nicole Megan, Lamba, Simona, Mauri, Gianluca, Durinikova, Erika, Vitiello, Pietro Paolo, Lorenzato, Annalisa, Avolio, Marco, Piumatti, Eleonora, Bonoldi, Emanuela, Aquilano, Maria Costanza, Arena, Sabrina, Sartore-Bianchi, Andrea, Siena, Salvatore, Trusolino, Livio, Donalisio, Manuela, Russo, Mariangela, Di Nicolantonio, Federica, Lembo, David, Bardelli, Alberto

المساهمون: A. Sogari, E. Rovera, G. Grasso, E. Mariella, N.M. Reilly, S. Lamba, G. Mauri, E. Durinikova, P.P. Vitiello, A. Lorenzato, M. Avolio, E. Piumatti, E. Bonoldi, M.C. Aquilano, S. Arena, A. Sartore-Bianchi, S. Siena, L. Trusolino, M. Donalisio, M. Russo, F. Di Nicolantonio, D. Lembo, A. Bardelli

مصطلحات موضوعية: DNA repair, chemotherapy, colibactin, colorectal cancer, microbiota, resistance, Settore MED/06 - Oncologia Medica

Relation: info:eu-repo/semantics/altIdentifier/pmid/38228147; info:eu-repo/semantics/altIdentifier/wos/WOS:001201743300001; volume:5; issue:2; firstpage:1; lastpage:31; numberofpages:31; journal:CELL REPORTS MEDICINE; https://hdl.handle.net/2434/1032012; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85185373290

الاتاحة: https://hdl.handle.net/2434/1032012
https://doi.org/10.1016/j.xcrm.2023.101376

المؤلفون: Mariella, Elisa, Grasso, Gaia, Miotto, Martina, Buzo, Kristi, Reilly, Nicole Megan, Andrei, Pietro, Vitiello, Pietro Paolo, Crisafulli, Giovanni, Arena, Sabrina, Rospo, Giuseppe, Corti, Giorgio, Lorenzato, Annalisa, Cancelliere, Carlotta, Barault, Ludovic, Gionfriddo, Giulia, Linnebacher, Michael, Russo, Mariangela, Di Nicolantonio, Federica, Bardelli, Alberto

المساهمون: Cancer Research UK, European Research Council, Fondazione AIRC per la ricerca sul cancro ETS, Innovative Medicines Initiative, Ministero della Salute

المصدر: Molecular Oncology ; volume 18, issue 6, page 1460-1485 ; ISSN 1574-7891 1878-0261

الاتاحة: http://dx.doi.org/10.1002/1878-0261.13622
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.13622

المؤلفون: Battuello, Paolo, Corti, Giorgio, Bartolini, Alice, Lorenzato, Annalisa, Sogari, Alberto, Russo, Mariangela, Di Nicolantonio, Federica, Bardelli, Alberto, Crisafulli, Giovanni

المساهمون: International Accelerator Award, Cancer Research UK, FC AECC, AIRC, European Research Council

المصدر: Briefings in Bioinformatics ; volume 25, issue 4 ; ISSN 1467-5463 1477-4054

الاتاحة: http://dx.doi.org/10.1093/bib/bbae249
https://academic.oup.com/bib/article-pdf/25/4/bbae249/57845364/bbae249.pdf

المؤلفون: Falcinelli, Marta, Dell’Omo, Giulia, Grassi, Elena, Mariella, Elisa, Leto, Simonetta Maria, Scardellato, Sharon, Lorenzato, Annalisa, Arena, Sabrina, Bertotti, Andrea, Trusolino, Livio, Bardelli, Alberto, d’Adda di Fagagna, Fabrizio

المساهمون: AIRC 5x1000

المصدر: Cell Death & Disease ; volume 14, issue 2 ; ISSN 2041-4889

الاتاحة: http://dx.doi.org/10.1038/s41419-023-05640-3
https://www.nature.com/articles/s41419-023-05640-3.pdf
https://www.nature.com/articles/s41419-023-05640-3

المؤلفون: Durinikova, Erika, Reilly, Nicole M, Buzo, Kristi, Mariella, Elisa, Chilà, Rosaria, Lorenzato, Annalisa, Dias, João M L, Grasso, Gaia, Pisati, Federica, Lamba, Simona, Corti, Giorgio, Degasperi, Andrea, Cancelliere, Carlotta, Mauri, Gianluca, Andrei, Pietro, Linnebacher, Michael, Marsoni, Silvia, Siena, Salvatore, Sartore-Bianchi, Andrea, Nik-Zainal, Serena, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina

المساهمون: Durinikova, Erika, Reilly, Nicole M, Buzo, Kristi, Mariella, Elisa, Chilà, Rosaria, Lorenzato, Annalisa, Dias, João M L, Grasso, Gaia, Pisati, Federica, Lamba, Simona, Corti, Giorgio, Degasperi, Andrea, Cancelliere, Carlotta, Mauri, Gianluca, Andrei, Pietro, Linnebacher, Michael, Marsoni, Silvia, Siena, Salvatore, Sartore-Bianchi, Andrea, Nik-Zainal, Serena, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina

Relation: info:eu-repo/semantics/altIdentifier/pmid/35881546; firstpage:OF1; lastpage:OF16; numberofpages:16; journal:CLINICAL CANCER RESEARCH; info:eu-repo/grantAgreement/EC/H2020/101020342; http://hdl.handle.net/2318/1872758

الاتاحة: http://hdl.handle.net/2318/1872758
https://doi.org/10.1158/1078-0432.CCR-22-0875

المؤلفون: Pessei, Valeria, Macagno, Marco, Mariella, Elisa, Congiusta, Noemi, Battaglieri, Vittorio, Battuello, Paolo, Viviani, Marco, Gionfriddo, Giulia, Lamba, Simona, Lorenzato, Annalisa, Oddo, Daniele, Idrees, Fariha, Cavaliere, Alessandro, Bartolini, Alice, Guarrera, Simonetta, Linnebacher, Michael, Monteonofrio, Laura, Cardone, Luca, Milella, Michele, Bertotti, Andrea

المصدر: Genome Medicine; 10/9/2024, Vol. 16 Issue 1, p1-16, 16p

مصطلحات موضوعية: CELL-free DNA, DNA demethylation, NUCLEIC acids, DNA methylation, CELL cycle, CIRCULATING tumor DNA

المؤلفون: Ha, Dat P., Shin, Woo-Jin, Liu, Ze, Doche, Michael E., Lau, Roy, Leli, Nektaria Maria, Conn, Crystal S., Russo, Mariangela, Lorenzato, Annalisa, Koumenis, Constantinos, Yu, Min, Mumenthaler, Shannon M., Lee, Amy S.

المصدر: Cell & Bioscience; 9/6/2024, Vol. 14 Issue 1, p1-25, 25p

مصطلحات موضوعية: CARDIAC glycosides, CHEMICAL libraries, COLON cancer, SARS-CoV-2, ENDOPLASMIC reticulum, GLUCOSE-regulated proteins

المؤلفون: Lorenzato, Annalisa, Magrì, Alessandro, Matafora, Vittoria, Audrito, Valentina, Arcella, Pamela, Lazzari, Luca, Montone, Monica, Lamba, Simona, Deaglio, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Bachi, Angela, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina

المساهمون: Lorenzato, Annalisa, Magrì, Alessandro, Matafora, Vittoria, Audrito, Valentina, Arcella, Pamela, Lazzari, Luca, Montone, Monica, Lamba, Simona, Deaglio, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Bachi, Angela, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina

مصطلحات موضوعية: ROS, Vitamin C, cetuximab, colorectal cancer, drug resistance, ferroptosi, glucose metabolism, oxidative stress

Relation: info:eu-repo/semantics/altIdentifier/pmid/32183295; info:eu-repo/semantics/altIdentifier/wos/WOS:000530232300161; volume:12; issue:3; firstpage:1; lastpage:22; numberofpages:22; journal:CANCERS; http://hdl.handle.net/2318/1738329; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85087004816; https://www.mdpi.com/2072-6694/12/3/685/htm

الاتاحة: http://hdl.handle.net/2318/1738329
https://doi.org/10.3390/cancers12030685
https://www.mdpi.com/2072-6694/12/3/685/htm

المؤلفون: Amodio, Vito, Yaeger, Rona, Arcella, Pamela, Cancelliere, Carlotta, Lamba, Simona, Lorenzato, Annalisa, Arena, Sabrina, Montone, Monica, Mussolin, Benedetta, Bian, Yu, Whaley, Adele, Pinnelli, Marika, Murciano-Goroff, Yonina R, Vakiani, Efsevia, Valeri, Nicola, Liao, Wei-Li, Bhalkikar, Anuja, Thyparambil, Sheeno, Zhao, Hui-Yong, de Stanchina, Elisa, Marsoni, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Li, Bob T, Rosen, Neal, Di Nicolantonio, Federica, Bardelli, Alberto, Misale, Sandra

المساهمون: Amodio, Vito, Yaeger, Rona, Arcella, Pamela, Cancelliere, Carlotta, Lamba, Simona, Lorenzato, Annalisa, Arena, Sabrina, Montone, Monica, Mussolin, Benedetta, Bian, Yu, Whaley, Adele, Pinnelli, Marika, Murciano-Goroff, Yonina R, Vakiani, Efsevia, Valeri, Nicola, Liao, Wei-Li, Bhalkikar, Anuja, Thyparambil, Sheeno, Zhao, Hui-Yong, de Stanchina, Elisa, Marsoni, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Li, Bob T, Rosen, Neal, Di Nicolantonio, Federica, Bardelli, Alberto, Misale, Sandra

Relation: info:eu-repo/semantics/altIdentifier/pmid/32430388; info:eu-repo/semantics/altIdentifier/wos/WOS:000558688700022; volume:10; issue:8; firstpage:1129; lastpage:1139; numberofpages:11; journal:CANCER DISCOVERY; info:eu-repo/grantAgreement/EC/H2020/724748; http://hdl.handle.net/2318/1740015; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85088308512; https://cancerdiscovery.aacrjournals.org/content/early/2020/05/12/2159-8290.CD-20-0187.full-text.pdf

الاتاحة: http://hdl.handle.net/2318/1740015
https://doi.org/10.1158/2159-8290.CD-20-0187
https://cancerdiscovery.aacrjournals.org/content/early/2020/05/12/2159-8290.CD-20-0187.full-text.pdf

المؤلفون: Arena, Sabrina, Corti, Giorgio, Durinikova, Erika, Montone, Monica, Reilly, Nicole M, Russo, Mariangela, Lorenzato, Annalisa, Arcella, Pamela, Lazzari, Luca, Rospo, Giuseppe, Pagani, Massimiliano, Cancelliere, Carlotta, Negrino, Carola, Isella, Claudio, Bartolini, Alice, Cassingena, Andrea, Amatu, Alessio, Mauri, Gianluca, Sartore-Bianchi, Andrea, Mittica, Gloria, Medico, Enzo, Marsoni, Silvia, Linnebacher, Michael, Abrignani, Sergio, Siena, Salvatore, Di Nicolantonio, Federica, Bardelli, Alberto

المساهمون: Arena, Sabrina, Corti, Giorgio, Durinikova, Erika, Montone, Monica, Reilly, Nicole M, Russo, Mariangela, Lorenzato, Annalisa, Arcella, Pamela, Lazzari, Luca, Rospo, Giuseppe, Pagani, Massimiliano, Cancelliere, Carlotta, Negrino, Carola, Isella, Claudio, Bartolini, Alice, Cassingena, Andrea, Amatu, Alessio, Mauri, Gianluca, Sartore-Bianchi, Andrea, Mittica, Gloria, Medico, Enzo, Marsoni, Silvia, Linnebacher, Michael, Abrignani, Sergio, Siena, Salvatore, Di Nicolantonio, Federica, Bardelli, Alberto

Relation: info:eu-repo/semantics/altIdentifier/pmid/31831554; info:eu-repo/semantics/altIdentifier/wos/WOS:000522838400020; firstpage:1; lastpage:14; numberofpages:14; journal:CLINICAL CANCER RESEARCH; info:eu-repo/grantAgreement/EC/H2020/635342-2; http://hdl.handle.net/2318/1728652; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85081944725

الاتاحة: http://hdl.handle.net/2318/1728652
https://doi.org/10.1158/1078-0432.CCR-19-2409

المؤلفون: Russo, Mariangela, Lamba, Simona, Lorenzato, Annalisa, SOGARI, ALBERTO, Corti, Giorgio, Rospo, Giuseppe, Mussolin, Benedetta, Montone, Monica, Lazzari, Luca, Arena, Sabrina, Oddo, Daniele, Linnebacher, Michael, Sartore-Bianchi, Andrea, Pietrantonio, Filippo, Siena, Salvatore, Di Nicolantonio, Federica, Bardelli, Alberto

المساهمون: Russo, Mariangela*, Lamba, Simona, Lorenzato, Annalisa, Sogari, Alberto, Corti, Giorgio, Rospo, Giuseppe, Mussolin, Benedetta, Montone, Monica, Lazzari, Luca, Arena, Sabrina, Oddo, Daniele, Linnebacher, Michael, Sartore-Bianchi, Andrea, Pietrantonio, Filippo, Siena, Salvatore, Di Nicolantonio, Federica, Bardelli, Alberto

مصطلحات موضوعية: Chemistry (all), Biochemistry, Genetics and Molecular Biology (all), Physics and Astronomy (all)

Relation: info:eu-repo/semantics/altIdentifier/pmid/29895949; info:eu-repo/semantics/altIdentifier/wos/WOS:000434926000001; volume:9; issue:1; firstpage:2287; lastpage:2298; numberofpages:12; journal:NATURE COMMUNICATIONS; http://hdl.handle.net/2318/1675614; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85048366199; http://www.nature.com/ncomms/index.html

الاتاحة: http://hdl.handle.net/2318/1675614
https://doi.org/10.1038/s41467-018-04506-z
http://www.nature.com/ncomms/index.html

المؤلفون: Rospo, Giuseppe, Lorenzato, Annalisa, Amirouchene-Angelozzi, Nabil, Magrì, Alessandro, Cancelliere, Carlotta, Corti, Giorgio, Negrino, Carola, Amodio, Vito, Montone, Monica, Bartolini, Alice, Barault, Ludovic, Novara, Luca, Isella, Claudio, Medico, Enzo, Bertotti, Andrea, Trusolino, Livio, Germano, Giovanni, Di Nicolantonio, Federica, Bardelli, Alberto

المصدر: Genome Medicine, 11(1), 42, (2019-06-28)

مصطلحات موضوعية: Colorectal cancer, Neoantigen, DNA repair, Immune response, Mutational signature

Relation: https://zenodo.org/communities/fp7-bmc; https://zenodo.org/communities/eu; oai:zenodo.org:3263999

الاتاحة: https://doi.org/10.1186/s13073-019-0654-6

المؤلفون: PIGNOCHINO, YMERA, D'AMBROSIO, LORENZO, ALIBERTI, Sandra, PALESANDRO, ERICA, BOCCONE, Paola, GALIZIA, DANILO, MIANO, Sara, CHIABOTTO, GIULIA, NAPIONE, Lucia, SANGIOLO, Dario, PASINI, Barbara, CHIORINO, Giovanna, AGLIETTA, Massimo, Capozzi, Federica, Dell'Aglio, Carmine, Basiricò, Marco, Canta, Marta, Lorenzato, Annalisa, Vignolo Lutati, Francesca, Gammaitoni, Loretta, Benassi, Maria Serena, Grignani, Giovanni

المساهمون: Pignochino, Ymera, Capozzi, Federica, D'Ambrosio, Lorenzo, Dell'Aglio, Carmine, Basiricò, Marco, Canta, Marta, Lorenzato, Annalisa, Vignolo Lutati, Francesca, Aliberti, Sandra, Palesandro, Erica, Boccone, Paola, Galizia, Danilo, Miano, Sara, Chiabotto, Giulia, Napione, Lucia, Gammaitoni, Loretta, Sangiolo, Dario, Benassi, Maria Serena, Pasini, Barbara, Chiorino, Giovanna, Aglietta, Massimo, Grignani, Giovanni

مصطلحات موضوعية: Bone and soft tissue sarcoma, DNA-damaging agent, Drug synergism, Olaparib, PARP1 inhibitor, Predictive biomarker, Trabectedin, Molecular Medicine, Oncology, Cancer Research

Relation: info:eu-repo/semantics/altIdentifier/pmid/28454547; info:eu-repo/semantics/altIdentifier/wos/WOS:000400251800002; volume:Apr 28;16; issue:1; firstpage:1; lastpage:15; numberofpages:15; journal:MOLECULAR CANCER; http://hdl.handle.net/2318/1636100; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85018432076; http://www.molecular-cancer.com/start.asp; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410089/

الاتاحة: http://hdl.handle.net/2318/1636100
https://doi.org/10.1186/s12943-017-0652-5
http://www.molecular-cancer.com/start.asp
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410089/

المؤلفون: Siravegna, Giulia, Lazzari, Luca, Crisafulli, Giovanni, Sartore-Bianchi, Andrea, Mussolin, Benedetta, Cassingena, Andrea, Martino, Cosimo, Lanman, Richard B., Nagy, Rebecca J., Fairclough, Stephen, Rospo, Giuseppe, Corti, Giorgio, Bartolini, Alice, Arcella, Pamela, Montone, Monica, Lodi, Francesca, Lorenzato, Annalisa, Vanzati, Alice, Valtorta, Emanuele, Cappello, Giovanni, Bertotti, Andrea, Lonardi, Sara, Zagonel, Vittorina, Leone, Francesco, Russo, Mariangela, Balsamo, Antonella, Truini, Mauro, Di Nicolantonio, Federica, Amatu, Alessio, Bonazzina, Erica, Ghezzi, Silvia, Regge, Daniele, Vanzulli, Angelo, Trusolino, Livio, Siena, Salvatore, Marsoni, Silvia, Bardelli, Alberto

المساهمون: Regione del Veneto, Seventh Framework Programme, Horizon 2020 Framework Programme

المصدر: Cancer Cell ; volume 34, issue 1, page 148-162.e7 ; ISSN 1535-6108

الاتاحة: http://dx.doi.org/10.1016/j.ccell.2018.06.004
https://api.elsevier.com/content/article/PII:S1535610818302617?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1535610818302617?httpAccept=text/plain

المؤلفون: TORCHIARO, ERICA, LORENZATO, Annalisa, OLIVERO, Martina, VALDEMBRI, Donatella, GAGLIARDI, PAOLO ARMANDO, GAI, Marta, ERRIQUEZ, JESSICA, SERINI, Guido, DI RENZO, Maria Flavia

المساهمون: Torchiaro, Erica, Lorenzato, Annalisa, Olivero, Martina, Valdembri, Donatella, Gagliardi, Paolo Armando, Gai, Marta, Erriquez, Jessica, Serini, Guido, Di Renzo, Maria Flavia

مصطلحات موضوعية: cell adhesion, fibronectin, hematogenous metastasi, p90RSK, peritoneal metastasis

Relation: info:eu-repo/semantics/altIdentifier/pmid/26625210; info:eu-repo/semantics/altIdentifier/wos/WOS:000369950300053; volume:7; issue:1; firstpage:712; lastpage:728; numberofpages:17; journal:ONCOTARGET; http://hdl.handle.net/2318/1593671; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85009775088

الاتاحة: http://hdl.handle.net/2318/1593671
https://doi.org/10.18632/oncotarget.6412

المؤلفون: DANI, NADIA, OLIVERO, Martina, LORENZATO, Annalisa, Cuvertino S, Patane’ S, Van Duist M, MARESCHI, Katia, Fagioli F, DI RENZO, Maria Flavia

المساهمون: Dani N, Olivero M, Lorenzato A, Cuvertino S, Patane’ S, Van Duist M, Mareschi K, Fagioli F, Di Renzo MF

Relation: ispartofbook:101st Annual Meeting AACR; 101st Annual Meeting AACR; firstpage:678; lastpage:678; numberofpages:1; http://hdl.handle.net/2318/79371

الاتاحة: http://hdl.handle.net/2318/79371

المؤلفون: Bardella, Chiara, Olivero, Martina, Lorenzato, Annalisa, Geuna, Massimo, Adam, Julie, O'Flaherty, Linda, Rustin, Pierre, Tomlinson, Ian, Pollard, Patrick J., Di Renzo, Maria Flavia

المصدر: Molecular and Cellular Biology ; volume 32, issue 15, page 3081-3094 ; ISSN 1098-5549

الاتاحة: http://dx.doi.org/10.1128/mcb.06160-11
https://journals.asm.org/doi/pdf/10.1128/MCB.06160-11
https://www.tandfonline.com/doi/pdf/10.1128/MCB.06160-11

المؤلفون: Magrì, Alessandro, Germano, Giovanni, Lorenzato, Annalisa, Lamba, Simona, Chilà, Rosaria, Montone, Monica, Amodio, Vito, Ceruti, Tommaso, Sassi, Francesco, Arena, Sabrina, Abrignani, Sergio, D’Incalci, Maurizio, Zucchetti, Massimo, Di Nicolantonio, Federica, Bardelli, Alberto

المصدر: Science Translational Medicine ; volume 12, issue 532 ; ISSN 1946-6234 1946-6242

الاتاحة: http://dx.doi.org/10.1126/scitranslmed.aay8707
https://syndication.highwire.org/content/doi/10.1126/scitranslmed.aay8707
https://www.science.org/doi/pdf/10.1126/scitranslmed.aay8707

المؤلفون: Brière, Jean-Jacques, Favier, Judith, Bénit, Paule, Ghouzzi, Vincent El, Lorenzato, Annalisa, Rabier, Daniel, Di Renzo, Maria Flavia, Gimenez-Roqueplo, Anne-Paule, Rustin, Pierre

مصطلحات موضوعية: ARTICLES

وصف الملف: text/html

Relation: http://hmg.oxfordjournals.org/cgi/content/short/14/21/3263; http://dx.doi.org/10.1093/hmg/ddi359

الاتاحة: http://hmg.oxfordjournals.org/cgi/content/short/14/21/3263
https://doi.org/10.1093/hmg/ddi359