المؤلفون: Jonas Walter, Silvia Bolognin, Suresh K. Poovathingal, Stefano Magni, Deborah Gérard, Paul M.A. Antony, Sarah L. Nickels, Luis Salamanca, Emanuel Berger, Lisa M. Smits, Kamil Grzyb, Rita Perfeito, Fredrik Hoel, Xiaobing Qing, Jochen Ohnmacht, Michele Bertacchi, Javier Jarazo, Tomasz Ignac, Anna S. Monzel, Laura Gonzalez-Cano, Rejko Krüger, Thomas Sauter, Michèle Studer, Luis Pereira de Almeida, Karl J. Tronstad, Lasse Sinkkonen, Alexander Skupin, Jens C. Schwamborn

المصدر: Cell Reports, Vol 37, Iss 3, Pp 109864- (2021)

مصطلحات موضوعية: LRRK2, Parkinson's disease, NR2F1, dopaminergic neurons, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721013310; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/2b9fa19fd71645ae8efd92a4e547da7e

المؤلفون: Asad Jan, Brandon Jansonius, Alberto Delaidelli, Forum Bhanshali, Yi Andy An, Nelson Ferreira, Lisa M. Smits, Gian Luca Negri, Jens C. Schwamborn, Poul H. Jensen, Ian R. Mackenzie, Stefan Taubert, Poul H. Sorensen

المصدر: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)

مصطلحات موضوعية: eEF2K, Parkinson disease, Alpha synuclein, Oxidative stress, Neurotoxicity, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-018-0554-9; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/e23110f14d4a4b2fa31d3af3eb5018a9

المؤلفون: Anna S. Monzel, Lisa M. Smits, Kathrin Hemmer, Siham Hachi, Edinson Lucumi Moreno, Thea van Wuellen, Javier Jarazo, Jonas Walter, Inga Brüggemann, Ibrahim Boussaad, Emanuel Berger, Ronan M.T. Fleming, Silvia Bolognin, Jens C. Schwamborn

المصدر: Stem Cell Reports, Vol 8, Iss 5, Pp 1144-1154 (2017)

مصطلحات موضوعية: organoid, stem cells, neural stem cells, midbrain, Parkinson’s disease, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671117301169; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/1f250250cc794665b371c2344ef28541

المؤلفون: Eiichiro Mori, Joachim Luginbühl, Sonia Sabate-Soler, Jens Christian Schwamborn, Silvia Bolognin, Alexander Skupin, Stefano Magni, Kaoru Kinugawa, Kamil Grzyb, Lisa M. Smits, Jay W. Shin

المصدر: Cell and Tissue Research

مصطلحات موضوعية: Cell type, Histology, Biology, Serotonergic, Pathology and Forensic Medicine, Single-cell RNA sequencing, Glutamatergic, Dopamine, Organoid, medicine, Humans, health care economics and organizations, Neural stem cells, Sequence Analysis, RNA, Dopaminergic Neurons, Dopaminergic, Midbrain organoids, Neuronal subtypes, Regular Article, Cell Differentiation, Cell Biology, Neural stem cell, Organoids, nervous system, GABAergic, Electrophysiological activity, Transcriptome, Neuroscience, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ce078992e27c7d0929141749ee7a79
http://europepmc.org/articles/PMC7683480

المؤلفون: Kamil Grzyb, Rejko Krüger, Jochen Ohnmacht, Lasse Sinkkonen, Laura Gonzalez-Cano, Tomasz Ignac, Luis Salamanca, Emanuel Berger, Karl Johan Tronstad, Lisa M. Smits, Jens Christian Schwamborn, Paul Antony, Silvia Bolognin, Alexander Skupin, Michèle Studer, Javier Jarazo, Fredrik Hoel, Thomas Sauter, Sarah Louise Nickels, Xiaobing Qing, Anna S. Monzel, Jonas Walter, Rita Perfeito, Deborah Gérard, Luís Pereira de Almeida, Stefano Magni, Michele Bertacchi, Suresh Poovathingal

المصدر: Cell Reports, Vol 37, Iss 3, Pp 109864-(2021)
Cell reports

مصطلحات موضوعية: Male, Parkinson's disease, Time Factors, Biochemistry, biophysics & molecular biology [F05] [Life sciences], NEURAL STEM-CELLS, medicine.disease_cause, Neural Stem Cells, RNA-Seq, Biology (General), Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant], SPECIFICATION, Mice, Knockout, Mutation, Neurogenesis, Dopaminergic, Cell Cycle, Brain, LRRK2, Parkinson Disease, Neuroepithelial cell, Phenotype, LRRK2 MUTATION, Female, Stem cell, Single-Cell Analysis, Life Sciences & Biomedicine, Signal Transduction, EXPRESSION, Mice, 129 Strain, QH301-705.5, Cell Survival, Induced Pluripotent Stem Cells, Biology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, General Biochemistry, Genetics and Molecular Biology, Cell Line, NEUROGENESIS, medicine, Animals, Humans, Transcription factor, OLFACTORY-BULB, Cell Proliferation, COUP Transcription Factor I, Science & Technology, IDENTIFICATION, GRANULE CELLS, Dopaminergic Neurons, OPTIC ATROPHY, Cell Biology, medicine.disease, NR2F1, COUP-TFI, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d0963bff88e50986d632a723edeb86
https://lirias.kuleuven.be/handle/20.500.12942/715986

المؤلفون: Silvia Bolognin, Alexander Skupin, Sarah Louise Nickels, Kamil Grzyb, Stefano Magni, Lisa M. Smits, Rejko Krüger, Jens Christian Schwamborn, Paul Antony

المصدر: Biomedical Science and Engineering. 4

مصطلحات موضوعية: Parkinson's disease, Organoid, medicine, General Medicine, Biology, medicine.disease, LRRK2, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bb3d5be64a51fd794682bc5f6b604b3b
https://doi.org/10.4081/bse.2021.137

المؤلفون: Alise Zagare, Kyriaki Barmpa, Semra Smajic, Lisa M. Smits, Kamil Grzyb, Anne Grünewald, Alexander Skupin, Sarah L. Nickels, Jens C. Schwamborn

المصدر: American journal of human genetics. 109(2)

مصطلحات موضوعية: Neurogenesis, Glycine, GATA3 Transcription Factor, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Models, Biological, Amyloid beta-Protein Precursor, Mesencephalon, Genetics, Serine, Humans, Genetics (clinical), Sequence Analysis, RNA, Gene Expression Regulation, Developmental, Cell Differentiation, Parkinson Disease, HSP40 Heat-Shock Proteins, Embryo, Mammalian, Organoids, Amino Acid Substitution, Mutation, Cytokines, Genetics & genetic processes [F10] [Life sciences], Single-Cell Analysis, Génétique & processus génétiques [F10] [Sciences du vivant], Carrier Proteins, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4d37d2ddff5ae06fe292ec96e51bfa
https://pubmed.ncbi.nlm.nih.gov/35077669

المؤلفون: Peter Ertl, Emanuel Berger, Silvia Bolognin, Sarah Spitz, Julie M Rosser, Jens Christian Schwamborn, Cristian Zanetti, Mario Rothbauer, Philipp Crepaz, Lisa M. Smits, Martina Marchetti-Deschmann

المصدر: The Analyst. 146(7)

مصطلحات موضوعية: Parkinson's disease, Drug Evaluation, Preclinical, Biology, 01 natural sciences, Biochemistry, Analytical Chemistry, Midbrain, 03 medical and health sciences, chemistry.chemical_compound, Dopamine, Mesencephalon, Electrochemistry, Organoid, medicine, Environmental Chemistry, Humans, Induced pluripotent stem cell, Neurotransmitter, Spectroscopy, 030304 developmental biology, 0303 health sciences, Neurotransmitter Agents, 010401 analytical chemistry, Parkinson Disease, medicine.disease, 0104 chemical sciences, Biomarker (cell), Organoids, chemistry, Neuroscience, Oxidation-Reduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a61d6fbaeaa1589050d06c7a034d6e
https://pubmed.ncbi.nlm.nih.gov/33625407

المؤلفون: Jens Christian Schwamborn, Lisa M. Smits

المصدر: Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology

مصطلحات موضوعية: 0301 basic medicine, self organization, stem cell research, Parkinson's disease, Neurite, organoid, Context (language use), midbrain, Review, Biology, Midbrain, 03 medical and health sciences, Glutamatergic, Cell and Developmental Biology, 0302 clinical medicine, medicine, Organoid, lcsh:QH301-705.5, Oligodendrocyte differentiation, Cell Biology, medicine.disease, Neural stem cell, 030104 developmental biology, nervous system, lcsh:Biology (General), 030220 oncology & carcinogenesis, Parkinson’s disease, Neuroscience, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a41244022359d35759b91d286c6029
https://www.frontiersin.org/article/10.3389/fcell.2020.00359/full

المؤلفون: Ronan M. T. Fleming, Ibrahim Boussaad, Anna S. Monzel, Jens Christian Schwamborn, Javier Jarazo, Siham Hachi, Edinson Lucumi Moreno, Jonas Walter, Kathrin Hemmer, Emanuel Berger, Silvia Bolognin, Inga Brüggemann, Thea van Wuellen, Lisa M. Smits

المصدر: Stem Cell Reports, Vol 8, Iss 5, Pp 1144-1154 (2017)
Stem Cell Reports, 8(5), 1144-1154. Cell Press
Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, Neurogenesis, organoid, Neuroepithelial Cells, midbrain, Biology, Biochemistry, Midbrain, 03 medical and health sciences, Mesencephalon, stem cells, Report, Genetics, Organoid, medicine, Humans, lcsh:QH301-705.5, Cells, Cultured, Myelin Sheath, neural stem cells, lcsh:R5-920, Dopaminergic Neurons, Oligodendrocyte differentiation, Cell Biology, Human brain, Anatomy, Neural stem cell, Neuroepithelial cell, Organoids, 030104 developmental biology, medicine.anatomical_structure, nervous system, lcsh:Biology (General), Parkinson’s disease, Stem cell, lcsh:Medicine (General), Neuroscience, Developmental Biology, Cerebral organoid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e4ddd87759a76df23c4ff43db9e143
http://www.sciencedirect.com/science/article/pii/S2213671117301169

المؤلفون: Athanasios D. Spathis, Demosthenes Fokas, Constantin Tamvakopoulos, Xenophon Asvos, Zoe Cournia, Stavros Topouzis, Demetrios K. Vassilatis, Pavlos Alexakos, Christina Dalla, Lisa M. Smits, Hardy J. Rideout, Theodoros Karampelas, Jens Christian Schwamborn, Despina Ziavra, Xiaobing Qing

المصدر: Proceedings of the National Academy of Sciences. 114:3999-4004

مصطلحات موضوعية: Male, 0301 basic medicine, Parkinson's disease, Dopamine, GTP cyclohydrolase I, Substantia nigra, Pharmacology, Neuroprotection, Article, Cell Line, Antiparkinson Agents, 03 medical and health sciences, 0302 clinical medicine, Drug Stability, Nuclear Receptor Subfamily 4, Group A, Member 2, medicine, Animals, Humans, Molecular Targeted Therapy, Neurons, Mice, Inbred BALB C, Retinoid X Receptor alpha, Multidisciplinary, biology, Tyrosine hydroxylase, Dopaminergic, Brain, Parkinson Disease, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, biology.protein, Neuron, Protein Multimerization, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e688b127c2f26d9c1305711f54230e33
https://doi.org/10.1073/pnas.1616874114

المؤلفون: Jens Christian Schwamborn, Lisa M. Smits, Francisco Azuaje, Kathrin Hemmer, Sarah Louise Nickels, Silvia Bolognin, Alise Zagare, Paul Antony, Tony Kaoma, Isabel Rosety, Rejko Krueger, Philippe Lucarelli, Anna S. Monzel

المصدر: Parkinsonismrelated disorders. 75

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Computer science, Induced Pluripotent Stem Cells, Machine learning, computer.software_genre, Proof of Concept Study, Midbrain, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, Mesencephalon, Organoid, medicine, Humans, Oxidopamine, High content imaging, Learning classifier system, Microscopy, Confocal, business.industry, Dopaminergic Neurons, Dopaminergic, Neurotoxicity, medicine.disease, Flow Cytometry, Organoids, 030104 developmental biology, Neurology, Neurotoxicity Syndromes, Neurology (clinical), Artificial intelligence, Neurotoxic effect, Geriatrics and Gerontology, business, computer, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3280abdcf328e6dd9c0bf29caf36856
https://pubmed.ncbi.nlm.nih.gov/32534431

المؤلفون: Jens Christian Schwamborn, Christian Jordan, Silvia Bolognin, Sarah Spitz, Mudiwa Nathasia Muwanigwa, Cristian Zanetti, Michael Harasek, Lisa M. Smits, Peter Ertl, Emanuel Berger

المصدر: bioRxiv

مصطلحات موضوعية: Interstitial flow, Midbrain, Brain development, Computer science, Microfluidics, Organoid, Induced pluripotent stem cell, Dopaminergic neuron differentiation, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e23f97015fa424c2bb07ae1b81fc8a
https://doi.org/10.1101/869701

المؤلفون: Lisa M. Smits, Silvia Bolognin, Alexander Skupin, Paul Antony, Jens Christian Schwamborn, Kamil Grzyb, Stefano Magni, Rejko Krueger

المصدر: bioRxiv

مصطلحات موضوعية: 0303 health sciences, Cell type, Cell, Dopaminergic, Biology, 3. Good health, Midbrain, 03 medical and health sciences, Glutamatergic, 0302 clinical medicine, medicine.anatomical_structure, nervous system, Dopamine, medicine, Organoid, GABAergic, Neuroscience, 030217 neurology & neurosurgery, health care economics and organizations, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a646cd73971d1f8019bdb266470e62e

المؤلفون: Kyriaki Barmpa, Silvia Bolognin, Jens Christian Schwamborn, Paul Antony, Javier Jarazo, Jonathan Arias-Fuenzalida, Christian Jäger, Christine Klein, Aleksandar Rakovic, Gemma Gomez-Giro, Rejko Krüger, Philip Seibler, Ibrahim Boussaad, Xiaobing Qing, Lisa M. Smits, Anna S. Monzel, Jonas Walter, Isabel Rosety, Gérald Cruciani, Emanuel Berger

المصدر: bioRxiv

مصطلحات موضوعية: 0303 health sciences, Parkinson's disease, Point mutation, Autophagy, Dopaminergic, PINK1, Biology, Gene mutation, medicine.disease, Phenotype, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Mitophagy, medicine, Cancer research, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd93bff997c9bce95e74fda5a2b4af02

المؤلفون: Kathrin Hemmer, Jens Christian Schwamborn, Silvia Bolognin, Lisa M. Smits, Anna S. Monzel, Thea van Wuellen, Siham Hachi, Edinson Lucumi Moreno, Ronan M. T. Fleming

مصطلحات موضوعية: Neurite, Oligodendrocyte differentiation, Anatomy, Human brain, Biology, Midbrain, Neuroepithelial cell, medicine.anatomical_structure, nervous system, Organoid, medicine, Stem cell, Neuroscience, Cerebral organoid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4376848a4a20484218b2feba062c8e15

المؤلفون: Silvia Bolognin, Jens Christian Schwamborn, Kathrin Hemmer, Lisa M. Smits

المصدر: bioRxiv
Opera Medica et Physiologica

مصطلحات موضوعية: 0303 health sciences, Mutation, Protein aggregation, Biology, medicine.disease_cause, nervous system diseases, 3. Good health, Cell biology, Transplantation, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, In vivo, Immunology, Synuclein, medicine, Stem cell, Induced pluripotent stem cell, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80eb60862e2cd1234ff105451a6a544