المؤلفون: Ellen K Gagliani, Lisa M Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A Kovall

المصدر: PLoS Genetics, Vol 18, Iss 8, p e1010335 (2022)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/3d3ef8ff2e0245a7bfb1cb014a49f333

المؤلفون: Yi Kuang, Anna Pyo, Natanel Eafergan, Brittany Cain, Lisa M Gutzwiller, Ofri Axelrod, Ellen K Gagliani, Matthew T Weirauch, Raphael Kopan, Rhett A Kovall, David Sprinzak, Brian Gebelein

المصدر: PLoS Genetics, Vol 17, Iss 9, p e1009039 (2021)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/46e826c091ea4d9db920f08826b85963

المؤلفون: Arya Zandvakili, Ian Campbell, Lisa M Gutzwiller, Matthew T Weirauch, Brian Gebelein

المصدر: PLoS Genetics, Vol 14, Iss 4, p e1007289 (2018)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5902045?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/300e3ec1252f4d3790dfcd6027aac3b1

المؤلفون: Amy L Gresser, Lisa M Gutzwiller, Mackenzie K Gauck, Volker Hartenstein, Tiffany A Cook, Brian Gebelein

المصدر: PLoS ONE, Vol 10, Iss 8, p e0134915 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4529294?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6f62a1005f4448498d1793ce9f3625b2

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/journal_contribution/List_of_oligonucleotide_sequences_used_to_generate_the_labeled_probes_used_in_the_electrophoretic_mobility_shift_assays_/16679343

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s012

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/journal_contribution/List_of_DNA_sequences_used_to_generate_all_the_synthetic_reporter_and_expression_transgenic_constructs_/16679346

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s013

المؤلفون: Ellen K. Gagliani, Lisa M. Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J. Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A. Kovall

المصدر: PLoS genetics. 18(8)

مصطلحات موضوعية: Mammals, Cancer Research, Scalp, Receptors, Notch, Skull, Limb Deformities, Congenital, DNA, Scalp Dermatoses, Ectodermal Dysplasia, Genetics, Animals, Drosophila Proteins, Humans, Drosophila, Molecular Biology, Co-Repressor Proteins, Genetics (clinical), Ecology, Evolution, Behavior and Systematics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dce116c72ecde6d05251bcac93ec40
https://pubmed.ncbi.nlm.nih.gov/35951645

المؤلفون: Ellen K. Gagliani, Brian Gebelein, Tilman Borggrefe, Yi Kuang, Patrick J. Dolph, Rhett A. Kovall, Phillipp Hoffmeister, Aleksandra Turkiewicz, Emily Harding-Theobald, Yoshinobu Odaka, Franz Oswald, Stefanie Hauff, Lisa M. Gutzwiller

مصطلحات موضوعية: Cofactor binding, RBPJ, Chemistry, Notch signaling pathway, Wild type, Allele, Transcription factor, Null allele, Cell biology, Hairless

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48a3d161f94cc06c845756d7f7deccc1
https://doi.org/10.1101/2021.09.24.461537

المؤلفون: Xinjian Wang, Matthias Eckenweiler, Peter Hedera, Michael Zech, Juliane Winkelmann, Donald L. Gilbert, Derek E. Neilson, Shelli M. Homan, Jesse Slone, Nancy D. Leslie, Brian Gebelein, Lisa M. Gutzwiller, Jianfeng Xiao, Taosheng Huang, Robert B. Hufnagel, Elizabeth J. Leslie, Mark S. LeDoux, Friederike Wilbert

المصدر: Mov Disord

مصطلحات موضوعية: Dystonia, Genetics, Paraplegia, congenital, hereditary, and neonatal diseases and abnormalities, Spastic Paraplegia, Hereditary, Locus (genetics), Biology, medicine.disease, Article, nervous system diseases, Pedigree, Phenotype, Neurology, Genetic linkage, Dystonic Disorders, Mutation, medicine, Spastic, Humans, Neurology (clinical), Gene, Exome, Exome sequencing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c945930024c6953a2c0aaf6f5bc6f26f
https://pubmed.ncbi.nlm.nih.gov/34636445

المؤلفون: Brian Gebelein, Ellen K. Gagliani, Raphael Kopan, Natanel Eafergan, Rhett A. Kovall, Yi Kuang, Matthew T. Weirauch, Anna Pyo, Brittany Cain, Lisa M. Gutzwiller, Ofri Axelrod, David Sprinzak

المصدر: PLoS Genetics, Vol 17, Iss 9, p e1009039 (2021)
PLoS Genetics

مصطلحات موضوعية: Cancer Research, Life Cycles, Gene Expression, Electrophoretic Mobility Shift Assay, Restriction Fragment Mapping, QH426-470, Biochemistry, Larvae, Genes, Reporter, Transcription (biology), Gene expression, Drosophila Proteins, Genetics (clinical), Receptors, Notch, Chemistry, Drosophila Melanogaster, Eukaryota, Animal Models, Cell biology, Insects, Enhancer Elements, Genetic, Experimental Organism Systems, Lac Operon, Drosophila, Chemical characterization, Research Article, Transcriptional Activation, Arthropoda, DNA transcription, Notch signaling pathway, DNA binding assay, Biology, Research and Analysis Methods, DNA-binding protein, Model Organisms, DNA-binding proteins, Binding analysis, Genetics, Animals, Electrophoretic mobility shift assay, Gene Regulation, Molecular Biology Techniques, Enhancer, Molecular Biology, Psychological repression, Transcription factor, Ecology, Evolution, Behavior and Systematics, Binding Sites, Gene Mapping, Organisms, Biology and Life Sciences, Proteins, Invertebrates, Regulatory Proteins, Hairless, Repressor Proteins, Gene Expression Regulation, Animal Studies, Notch binding, Zoology, Entomology, Transcription Factors, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de114790586f27d05d91e1e85e0921ad
https://doaj.org/article/46e826c091ea4d9db920f08826b85963

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/EMSA_quantification_and_modeling_of_DNA_binding_states_/16679295

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s001

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/Specificity_of_1xSPS_sub_15_sub_2xCSL_sub_17_sub_and_2xCSL_sub_17_sub_mut_probes_as_unlabeled_competitors_for_Su_H_/16679301

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s002

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/cisBP_analysis_of_2xCSL_sub_17_sub_1xSPS_sub_15_sub_2xCSL15_and_1xSPS17_sequences_for_additional_transcription_factor_binding_site_motifs_/16679304

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s003

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/CSL_and_SPS_probes_with_different_flanking_sequences_show_similar_behaviors_in_EMSAs_/16679310

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s004

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/2xCSL_sub_17_sub_and_1xSPS_sub_15_sub_reporters_fail_to_mediate_Notch_activation_in_mesectoderm_cells_/16679325

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s008

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/_i_12xCSL_sub_17_sub_-lacZ_i_and_i_6xSPS_sub_15_sub_-lacZ_i_transgenic_reporters_behave_similarly_in_two_different_loci_/16679316

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s006

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/Synthetic_CSL_and_SPS_reporters_with_distinct_flanking_sequences_significantly_differ_in_expression_activity_in_larval_imaginal_discs_/16679322

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s007

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/lexA-H_sup_232_263_sup_fusion_protein_but_not_lexA_or_H_sup_232_263_sup_alone_represses_the_i_lacZ_i_reporters_driven_by_lexA_operator_and_CSL_SPS_binding_sites_/16679334

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s010

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/figure/Analysis_of_synthetic_SPS_and_CSL_reporter_activity_under_conditions_of_either_GFP_or_Hairless_overexpression_/16679328

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s009

المؤلفون: Yi Kuang (1873354), Anna Pyo (11478741), Natanel Eafergan (11478744), Brittany Cain (11478747), Lisa M. Gutzwiller (11478750), Ofri Axelrod (11478753), Ellen K. Gagliani (11478756), Matthew T. Weirauch (8154609), Raphael Kopan (93437), Rhett A. Kovall (9461208), David Sprinzak (217932), Brian Gebelein (781367)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Computational Biology, spss mediate stronger, repressor expression compared, regulating gene expression, mediate transcriptional outcomes, bf /< u, div >< p, also bind co, increased hairless co, l , c , repressor , notch intracellular domain, hairless repression complexes, p , h )/< u, monomeric csl sites, hairless co, , vivo <, vitro <

Relation: https://figshare.com/articles/dataset/Spreadsheet_containing_all_the_raw_data_used_to_generate_the_graphs_within_the_manuscript_/16679337

الاتاحة: https://doi.org/10.1371/journal.pgen.1009039.s011