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المؤلفون: V. Peter Collins, Panayiota Poirazi, Tom C. Freeman, Lisa Happerfield, Karen Plant, Lu Liu, Matthew T. Wayland, Magnus Backlund, Anastasis Oulas, Lawrence P. Petalidis
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المؤلفون: V. Peter Collins, Panayiota Poirazi, Tom C. Freeman, Lisa Happerfield, Karen Plant, Lu Liu, Matthew T. Wayland, Magnus Backlund, Anastasis Oulas, Lawrence P. Petalidis
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المؤلفون: V. Peter Collins, Panayiota Poirazi, Tom C. Freeman, Lisa Happerfield, Karen Plant, Lu Liu, Matthew T. Wayland, Magnus Backlund, Anastasis Oulas, Lawrence P. Petalidis
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المؤلفون: Susanne, Lager, Ulla, Sovio, Elizabeth, Eddershaw, Margaretha W, van der Linden, Cansu, Yazar, Emma, Cook, Lisa, Happerfield, Flora A, Jessop, Neil J, Sebire, D Stephen, Charnock-Jones, Gordon C S, Smith
المصدر: The Journal of physiologyReferences. 598(23)
مصطلحات موضوعية: Fetal Growth Retardation, Pre-Eclampsia, Pregnancy, Placenta, Infant, Newborn, Endothelial Cells, Humans, Female, CD8-Positive T-Lymphocytes
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المؤلفون: Lisa Happerfield, F. A. Jessop, Ulla Sovio, Cansu Yazar, Elizabeth Eddershaw, Neil J. Sebire, Susanne Lager, Gordon C. S. Smith, D. Stephen Charnock-Jones, Emma Cook, Margaretha W van der Linden
المساهمون: Lager, Susanne [0000-0003-3556-065X], Sovio, Ulla [0000-0002-0799-1105], Yazar, Cansu [0000-0003-2660-0111], Cook, Emma [0000-0002-6142-4443], Sebire, Neil J [0000-0001-5348-9063], Charnock-Jones, D Stephen [0000-0002-2936-4890], Smith, Gordon CS [0000-0003-2124-0997], Apollo - University of Cambridge Repository
مصطلحات موضوعية: 0301 basic medicine, CD31, Pathology, medicine.medical_specialty, Physiology, leukocytes, Placenta, Reproduktionsmedicin och gynekologi, CD8-Positive T-Lymphocytes, 03 medical and health sciences, small for gestational age, villitis of unknown aetiology, 0302 clinical medicine, Pre-Eclampsia, Pregnancy, image analysis, Obstetrics, Gynecology and Reproductive Medicine, medicine, Humans, small-for-gestational age, fibrin, Pathological, villous tissue, Fetal Growth Retardation, Eclampsia, business.industry, Infant, Newborn, Endothelial Cells, Gestational age, medicine.disease, endothelial cells, 030104 developmental biology, medicine.anatomical_structure, stereology, Small for gestational age, Female, pregnancy complication, business, pathologist scoring, Infiltration (medical), 030217 neurology & neurosurgery
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
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المؤلفون: Ruth T, Casey, Mary A, McLean, Basetti, Madhu, Benjamin G, Challis, Rogier, Ten Hoopen, Thomas, Roberts, Graeme R, Clark, Deborah, Pittfield, Helen L, Simpson, Venkata R, Bulusu, Kieran, Allinson, Lisa, Happerfield, Soo-Mi, Park, Alison, Marker, Olivier, Giger, Eamonn R, Maher, Ferdia A, Gallagher
المصدر: JCO precision oncology. 2
مصطلحات موضوعية: Article
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المؤلفون: Benjamin G, Challis, Narayanan, Kandasamy, Andrew S, Powlson, Olympia, Koulouri, Anand Kumar, Annamalai, Lisa, Happerfield, Alison J, Marker, Mark J, Arends, Serena, Nik-Zainal, Mark, Gurnell
المصدر: The Journal of Clinical Endocrinology and Metabolism
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, MutS Homolog 2 Protein, Neoplastic Syndromes, Hereditary, Adrenocortical Carcinoma, Humans, Female, Genetic Predisposition to Disease, Genetic Testing, Middle Aged, Special Features, Colorectal Neoplasms, Hereditary Nonpolyposis, Adrenal Cortex Neoplasms, Germ-Line Mutation
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المؤلفون: Elena A.B. Azizan, Gary J. Hoffman, Brian Y.H. Lam, Junhua Zhou, Alison Marker, Rhoda E. Kuc, Jennifer Clarke, Morris J. Brown, Lisa Happerfield, Stephen Newhouse
المصدر: The Journal of Clinical Endocrinology & Metabolism. 97:E819-E829
مصطلحات موضوعية: Adenoma, Adult, Male, Familial hyperaldosteronism, medicine.medical_specialty, Genotype, Endocrinology, Diabetes and Metabolism, education, Clinical Biochemistry, Adrenal Gland Neoplasms, Biology, Biochemistry, chemistry.chemical_compound, Endocrinology, Zona fasciculata, Internal medicine, Hyperaldosteronism, mental disorders, medicine, Humans, Aldosterone, Aged, Laser capture microdissection, Adrenal gland, Biochemistry (medical), Middle Aged, medicine.disease, Molecular biology, Phenotype, medicine.anatomical_structure, G Protein-Coupled Inwardly-Rectifying Potassium Channels, chemistry, Zona glomerulosa, Female, Zona Glomerulosa, Zona Fasciculata, psychological phenomena and processes
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المؤلفون: Laura J. Gay, Mark J. Arends, Panagiota N. Mitrou, Richard Bowman, Ashraf E. Ibrahim, Lisa Happerfield, Robert Luben, Alison McTaggart, Richard Y. Ball, Sheila A. Rodwell
المصدر: Nutrition and Cancer. 63:1000-1010
مصطلحات موضوعية: Adult, Male, Oncology, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, medicine.medical_specialty, Pathology, Colorectal cancer, Medicine (miscellaneous), Biology, MLH1, DNA Mismatch Repair, Surveys and Questionnaires, Internal medicine, Vegetables, medicine, Humans, Prospective Studies, Promoter Regions, Genetic, Prospective cohort study, Life Style, neoplasms, Adaptor Proteins, Signal Transducing, Aged, Nutrition and Dietetics, Smoking, Nuclear Proteins, Microsatellite instability, Promoter, DNA, Methylation, DNA Methylation, Middle Aged, medicine.disease, Immunohistochemistry, United Kingdom, digestive system diseases, Diet, Fruit, DNA methylation, Female, Microsatellite Instability, DNA mismatch repair, Colorectal Neoplasms, MutL Protein Homolog 1
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المؤلفون: Lizz F. Grimwade, Colin Tristram, Lisa Happerfield, Gary McIntosh, Paul Scorer, Amy E. Quinn, Michael A. Scott, Wendy N. Erber, Nigel H. Piggott, Marie Hall, Elaine M. Boyd, Mark Rees, A Bench
المصدر: British Journal of Haematology. 147:495-506
مصطلحات موضوعية: Male, Bone Marrow Cells, Biology, Exon, Mastocytosis, Systemic, hemic and lymphatic diseases, STAT5 Transcription Factor, medicine, Humans, Phosphorylation, Systemic mastocytosis, Protein kinase B, PI3K/AKT/mTOR pathway, STAT5, Aged, Myeloproliferative Disorders, Kinase, food and beverages, Hematology, Janus Kinase 2, Middle Aged, medicine.disease, Neoplasm Proteins, Proto-Oncogene Proteins c-kit, Chronic Disease, biology.protein, Cancer research, Female, Signal transduction, Megakaryocytes, Proto-Oncogene Proteins c-akt, Receptors, Thrombopoietin
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المصدر: International Journal of Experimental Pathology. 90:101-108
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Achalasia, Biology, Pathology and Forensic Medicine, Pathogenesis, Mice, Esophagus, Fibrosis, medicine, Animals, Genetic Predisposition to Disease, Molecular Biology, Myenteric plexus, Mice, Knockout, Tumor Suppressor Proteins, S100 Proteins, Histology, Original Articles, Cell Biology, medicine.disease, Esophageal Achalasia, Disease Models, Animal, medicine.anatomical_structure, Immunohistochemistry, Chronic Inflammatory Infiltrate
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المؤلفون: Matthew T. Wayland, Lawrence P. Petalidis, Anastasis Oulas, Lisa Happerfield, Lu Liu, Karen Plant, V. Peter Collins, Tom C. Freeman, Panayiota Poirazi, Magnus Bäcklund
المصدر: Petalidis, L P, Oulas, A, Backlund, M, Wayland, M T, Liu, L, Plant, K, Happerfield, L, Freeman, T C, Poirazi, P & Collins, V P 2008, ' Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data ', Molecular Cancer Therapeutics, vol. 7, no. 5, pp. 1013-1024 . https://doi.org/10.1158/1535-7163.MCT-07-0177
مصطلحات موضوعية: Cancer Research, Angiogenesis, Computational biology, Astrocytoma, Biology, Bioinformatics, Article, Text mining, Biomarkers, Tumor, medicine, Humans, Grading (tumors), Survival rate, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Brain Neoplasms, business.industry, Astrocytic Tumor, Gene Expression Profiling, Intracellular Signaling Peptides and Proteins, Reproducibility of Results, Neural Networks (Computer), Phosphoproteins, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, Survival Rate, Gene expression profiling, Oncology, Tumor Markers, Biological, Neural Networks, Computer, Apoptosis Regulatory Proteins, business, Algorithms
وصف الملف: application/pdf
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المؤلفون: Eamonn R. Maher, Derek Lim, Rick van Minkelen, Emma R. Woodward, Marc Tischkowitz, Ian M. Frayling, Lone Sunde, James Whitworth, Lisa Happerfield, Anne-Bine Skytte, Mark J. Arends
المساهمون: Clinical Genetics, Whitworth, James [0000-0002-3682-2298], Tischkowitz, Marc [0000-0002-7880-0628], Maher, Eamonn [0000-0002-6226-6918], Apollo - University of Cambridge Repository
المصدر: Whitworth, J, Skytte, A-B, Sunde, L, Lim, D H, Arends, M J, Happerfield, L, Frayling, I M, van Minkelen, R, Woodward, E R, Tischkowitz, M D & Maher, E R 2016, ' Multilocus Inherited Neoplasia Alleles Syndrome : A Case Series and Review ', JAMA oncology, vol. 2, no. 3, pp. 373-379 . https://doi.org/10.1001/jamaoncol.2015.4771
JAMA Oncology, 2(3), 373-379. American Medical Associationمصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Databases, Factual, Biology, 03 medical and health sciences, 0302 clinical medicine, Genetic disorder diagnosis, Locus heterogeneity, Neoplasms, Proto-Oncogene Proteins, Genotype, medicine, Humans, Genetic Predisposition to Disease, Allele, Exome sequencing, Alleles, Aged, Genetics, Tumor Suppressor Proteins, Cancer, High-Throughput Nucleotide Sequencing, Syndrome, Middle Aged, medicine.disease, Penetrance, 030104 developmental biology, MutS Homolog 2 Protein, Oncology, 030220 oncology & carcinogenesis, Mutation, Allelic heterogeneity, Female, Tumor Suppressor Protein p53
وصف الملف: application/pdf
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المؤلفون: Junhua Zhou, Mariann Bienz, Sumedha Garg, Morris J. Brown, Lalarukh Haris Shaikh, Elena A.B. Azizan, Alison Marker, Fiona E. Karet Frankl, Mark Gurnell, Ada E. D. Teo, Lisa Happerfield
المصدر: The New England journal of medicine. 373(15)
مصطلحات موضوعية: Adenoma, Adult, medicine.medical_specialty, Beta-catenin, Somatic cell, Adrenal Gland Neoplasm, Adrenal Gland Neoplasms, Hypokalemia, Article, Primary aldosteronism, Pregnancy, Internal medicine, Hyperaldosteronism, medicine, Humans, Aldosterone, beta Catenin, biology, business.industry, GNRHR, Wnt signaling pathway, General Medicine, Middle Aged, Receptors, LH, medicine.disease, Up-Regulation, Postmenopause, Endocrinology, Hypertension, Cancer research, biology.protein, Female, business, Pregnancy Complications, Neoplastic, Receptors, LHRH
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المؤلفون: Mariann Bienz, Lisa Happerfield, Alison Marker, Elena A.B. Azizan, Mark Gurnell, Sumedha Garg, Morris J. Brown, F.E. Karet Frankl, L. Haris Shaikh, Ada E. D. Teo, Junhua Zhou
المصدر: Annales d'Endocrinologie. 77:161-162
مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_specialty, Mutation, Microarray, Adenoma, Microarray analysis techniques, Endocrinology, Diabetes and Metabolism, Receptor expression, Wnt signaling pathway, General Medicine, Biology, medicine.disease, medicine.disease_cause, Transcriptome, 03 medical and health sciences, 030104 developmental biology, Endocrinology, Primary aldosteronism, Internal medicine, medicine
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المصدر: The Journal of Pathology. 193:A1-A49
مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Colorectal cancer, Normal tissue, Cancer, MLH1, medicine.disease, Pathology and Forensic Medicine, MSH2, Internal medicine, medicine, business, Immunostaining
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المؤلفون: Narayanan Kandasamy, Serena Nik-Zainal, Anand Kumar Annamalai, Lisa Happerfield, Joan Paterson, Mark Arends, Mark Gurnell
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المؤلفون: Adam Naguib, James C Cooke, Lisa Happerfield, Lucy Kerr, Laura J Gay, Robert N Luben, Richard Y Ball, Panagiota N Mitrou, Alison McTaggart, Mark J Arends
المساهمون: Luben, Robert [0000-0002-5088-6343], Apollo - University of Cambridge Repository
المصدر: BMC Cancer, Vol 11, Iss 1, p 123 (2011)
Naguib, A, Cooke, J C, Happerfield, L, Kerr, L, Gay, L J, Luben, R N, Ball, R Y, Mitrou, P N, McTaggart, A & Arends, M J 2011, ' Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study : associations with clinicopathological and dietary factors ', BMC Cancer, vol. 11, pp. 123 . https://doi.org/10.1186/1471-2407-11-123
BMC Cancerمصطلحات موضوعية: Male, Questionnaires, Cancer Research, Class I Phosphatidylinositol 3-Kinases, DNA Mutational Analysis, Gene mutation, Adenocarcinoma, medicine.disease_cause, Proto-Oncogene Mas, lcsh:RC254-282, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Sex Factors, Surgical oncology, Surveys and Questionnaires, medicine, Genetics, PTEN, Humans, neoplasms, PI3K/AKT/mTOR pathway, Genetic Association Studies, 030304 developmental biology, Aged, Regulation of gene expression, Aged, 80 and over, 0303 health sciences, Mutation, biology, PTEN Phosphohydrolase, Middle Aged, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Colonic Neoplasms, Cancer research, biology.protein, Disease Progression, Female, Research Article
وصف الملف: application/pdf; text/xml
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المؤلفون: Lisa Happerfield, Anthony O'Grady, Lilian Tee, Nicola Johnson, Elena Provenzano, David Allen, Elaine W. Kay, Mai Gu, Sarah E Pinder
المصدر: Applied immunohistochemistrymolecular morphology : AIMM. 18(6)
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Pathology, Histology, Receptor, ErbB-2, Concordance, Breast Neoplasms, Guidelines as Topic, HercepTest, Sensitivity and Specificity, Oracle, Pathology and Forensic Medicine, Automation, Breast cancer, Internal medicine, Biomarkers, Tumor, Medicine, Humans, Neoplasm Invasiveness, skin and connective tissue diseases, In Situ Hybridization, Fluorescence, Paraffin Embedding, medicine.diagnostic_test, Staining and Labeling, business.industry, medicine.disease, Immunohistochemistry, Neoplasm Proteins, Medical Laboratory Technology, Research Design, Fish
, Female, business, Asco cap, Fluorescence in situ hybridization -
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المؤلفون: Lizz F. Grimwade, David Bloxham, Lisa Happerfield, Wendy N. Erber, Rani Saward
المصدر: Journal of clinical pathology. 61(6)
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Tissue Fixation, Bone Marrow Cells, Biology, Pathology and Forensic Medicine, Flow cytometry, Immunophenotyping, Immunoenzyme Techniques, Antigen, Antigens, Neoplasm, medicine, Biomarkers, Tumor, Humans, Electronic Data Processing, Blood Cells, Immunoperoxidase, medicine.diagnostic_test, General Medicine, Alkaline Phosphatase, Molecular biology, Staining, medicine.anatomical_structure, Case-Control Studies, Hematologic Neoplasms, Alkaline phosphatase, Immunohistochemistry, Feasibility Studies, Bone marrow, Immunostaining