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1Academic Journal
المؤلفون: Amy E. Hutton, Jake Foster, Rebecca Crawshaw, Florence J. Hardy, Linus O. Johannissen, Thomas M. Lister, Emilie F. Gérard, Zachary Birch-Price, Richard Obexer, Sam Hay, Anthony P. Green
المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2Academic Journal
المؤلفون: Shaowei Zhang, Laura N. Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Kaylee Patel, Linus O. Johannissen, Lingyun Zhu, Matthew J. Cliff, Cunyu Yan, Giorgio Schirò, Martin Weik, Michiyo Sakuma, Colin W. Levy, David Leys, Derren J. Heyes, Nigel S. Scrutton
المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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3Academic Journal
المؤلفون: Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J. Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O. Johannissen, Colin W. Levy, Laura N. Jeffreys, Shaowei Zhang, Michiyo Sakuma, Jacques-Philippe Colletier, Sam Hay, Giorgio Schirò, Martin Weik, Nigel S. Scrutton, David Leys
المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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4Academic Journal
المؤلفون: Youngchan Kim, Federico Bertagna, Edeline M. D’Souza, Derren J. Heyes, Linus O. Johannissen, Eveliny T. Nery, Antonio Pantelias, Alejandro Sanchez-Pedreño Jimenez, Louie Slocombe, Michael G. Spencer, Jim Al-Khalili, Gregory S. Engel, Sam Hay, Suzanne M. Hingley-Wilson, Kamalan Jeevaratnam, Alex R. Jones, Daniel R. Kattnig, Rebecca Lewis, Marco Sacchi, Nigel S. Scrutton, S. Ravi P. Silva, Johnjoe McFadden
المصدر: Quantum Reports, Vol 3, Iss 1, Pp 80-126 (2021)
مصطلحات موضوعية: quantum biology, non-trivial quantum effects in biology, quantum tunnelling in enzyme-catalysed reactions, photosynthesis, synthetic light harvesting system, ion channel, Physics, QC1-999
وصف الملف: electronic resource
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5
المصدر: Barker, R, Yu, Y, De Maria, L, Johannissen, L & Scrutton, N 2022, ' The Mechanism of Action of Flavin-Dependent Halogenases ', ACS Catalysis, vol. 12, no. 24, pp. 15352–15360 . https://doi.org/10.1021/acscatal.2c05231
مصطلحات موضوعية: General Chemistry, Catalysis
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6
المؤلفون: Oliver J. Knowles, Linus O. Johannissen, Giacomo E. M. Crisenza, Sam Hay, David Leys, David J. Procter
المصدر: Knowles, O J, Johannissen, L O, Crisenza, G E M, Hay, S, Leys, D & Procter, D J 2022, ' A Vitamin B2-Photocatalysed Approach to Methionine Analogues ', Angewandte Chemie. International Edition, vol. 61, no. 50 . https://doi.org/10.1002/anie.202212158
مصطلحات موضوعية: Sulphide, sulfides, Riboflavin, Amino acid residues, Medicinal chemistry, chemistry, flavins, Catalysis, Photocatalyzed, Methionine, Bio-conjugation, Photocatalysis, Amino Acids, Sulfur compounds, Biomimetic processes, Racemethionine, Flavin, vitamin, Vitamins, General Medicine, General Chemistry, Chemical biology, peptide, Non-canonical amino acids, Peptides, Amino-acids, amino acid
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7
المؤلفون: Oliver J, Knowles, Linus O, Johannissen, Giacomo E M, Crisenza, Sam, Hay, David, Leys, David J, Procter
المصدر: Angewandte Chemie (International ed. in English). 61(50)
مصطلحات موضوعية: Methionine, Riboflavin, Vitamins, Amino Acids, Peptides, Catalysis, Racemethionine
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8
المؤلفون: Paulius Kantakevičius, Calvin Mathiah, Linus O. Johannissen, Sam Hay
المصدر: Journal of chemical theory and computation. 18(4)
مصطلحات موضوعية: Ions, Metals, Thermodynamics, Water, Physical and Theoretical Chemistry, Molecular Dynamics Simulation, Computer Science Applications, Chelating Agents
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9
المؤلفون: Linus O. Johannissen, Aoife Taylor, Samantha J.O. Hardman, Derren J. Heyes, Nigel S. Scrutton, Sam Hay
المصدر: ACS catalysis. 12(7)
مصطلحات موضوعية: General Chemistry, Catalysis
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10
المؤلفون: Thomas Butterfield, Philip Le Roy, Linus O. Johannissen, Colin Levy, Dharmendra S. Dheeman, Guadalupe Alvarez Gonzalez, Lewis Caiger, Trishnamoni Gautom, Neil Dixon, Karl Fisher
المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Gautom, T, Dheeman, D S, Levy, C, Butterfield, T, Alvarez Gonzalez, G, Le Roy, P, Caiger, L, Fisher, K, Johannissen, L & Dixon, N 2021, ' Structural basis of terephthalate recognition by solute binding protein TphC ', Nature Communications, vol. 12, no. 1, 6244 . https://doi.org/10.1038/s41467-021-26508-0مصطلحات موضوعية: Models, Molecular, Protein Conformation, Operon, Science, Phthalic Acids, General Physics and Astronomy, Comamonas/chemistry, Calorimetry, Crystallography, X-Ray, Ligands, Article, General Biochemistry, Genetics and Molecular Biology, Xenobiotics, Metabolic engineering, chemistry.chemical_compound, Bacterial Proteins, Bacterial Proteins/chemistry, Manchester Institute of Biotechnology, Biophysical chemistry, Polyethylene terephthalate, Fluorometry, Fluorometry/methods, Phthalic Acids/metabolism, Gene, Phylogeny, Xenobiotics/metabolism, Multidisciplinary, integumentary system, Chemistry, Binding protein, General Chemistry, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Ligand (biochemistry), Molecular Docking Simulation, Transporters, Monomer, Comamonas, Mutation, Biophysics, Ethylene glycol
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11
المؤلفون: Derren J. Heyes, Mohamed Amer, Emilia Z. Wojcik, Guo-Qiang Chen, John M. X. Hughes, Samantha J. O. Hardman, Helen S. Toogood, Shirley Tait, Linus O. Johannissen, Ian Sofian Yunus, Nigel S. Scrutton, Michael H. Smith, Matthew Faulkner, Patrik R. Jones, Robin Hoeven, Chenhao Sun
المساهمون: Commission of the European Communities, Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften EV
المصدر: Amer, M, Wojcik, E, Sun, C, Hoeven, R, Hughes, J, Faulkner, M, Yunus, I S, Tait, S, Johannissen, L, Hardman, S, Heyes, D, Chen, G-Q, Smith, M H, Jones, P R, Toogood, H & Scrutton, N 2020, ' Low Carbon Strategies for Sustainable Bio-alkane Gas Production and Renewable Energy ', Energy & Environmental Science . https://doi.org/10.1039/D0EE00095G
Energy & Environmental Scienceمصطلحات موضوعية: 0106 biological sciences, Technology, HOST, Chemistry, Multidisciplinary, Biomass, 01 natural sciences, 7. Clean energy, Liquefied petroleum gas, chemistry.chemical_compound, Engineering, STANDARD, FOOD WASTE, 0303 health sciences, HALOMONAS TD01, Energy, Waste management, Butane, Pollution, Renewable energy, Chemistry, Physical Sciences, Carbon dioxide, FATTY-ACIDS, VISIBLE-LIGHT, Life Sciences & Biomedicine, EXPRESSION, Engineering, Chemical, Energy & Fuels, ESCHERICHIA-COLI K-12, Environmental Sciences & Ecology, Industrial waste, 12. Responsible consumption, CLONING, 03 medical and health sciences, Propane, Manchester Institute of Biotechnology, 010608 biotechnology, Environmental Chemistry, BIOSYNTHESIS, 030304 developmental biology, Science & Technology, Renewable Energy, Sustainability and the Environment, business.industry, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Nuclear Energy and Engineering, chemistry, 13. Climate action, Carbon footprint, Environmental science, business, Environmental Sciences
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12
المؤلفون: Sam Hay, Linus O. Johannissen, Nigel S. Scrutton, Andreea Iulia Iorgu
المصدر: Johannissen, L O, Iorgu, A I, Scrutton, N & Hay, S 2019, ' What are the signatures of tunnelling in enzyme-catalysed reactions? ', Faraday Discussions . https://doi.org/10.1039/C9FD00044E
مصطلحات موضوعية: Materials science, Hydrogen, chemistry.chemical_element, Thermodynamics, Electron, 010402 general chemistry, 01 natural sciences, symbols.namesake, Reaction rate constant, Manchester Institute of Biotechnology, Kinetic isotope effect, Physical and Theoretical Chemistry, Adiabatic process, Quantum tunnelling, Arrhenius equation, 010405 organic chemistry, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Enzymes, 0104 chemical sciences, Marcus theory, Kinetics, chemistry, Biocatalysis, symbols, Quantum Theory
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document
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13
المؤلفون: Jaime Battye, Marc W. van der Kamp, Nicole G. H. Leferink, Sam Hay, Nigel S. Scrutton, Adrian J. Mulholland, Linus O. Johannissen, Kara E. Ranaghan
المصدر: Chembiochem
Leferink, N, Ranaghan, K E, Battye, J, Johannissen, L, Hay, S, Kamp, M W V D, Mulholland, A J & Scrutton, N 2020, ' Taming the reactivity of monoterpene synthases to guide regioselective product hydroxylation ', CHEMBIOCHEM, vol. 20, pp. 1-7 . https://doi.org/10.1002/cbic.201900672
Leferink, N G H, Ranaghan, K E, Battye, J, Johannissen, L O, Hay, S, Van Der Kamp, M W, Mulholland, A J & Scrutton, N S 2019, ' Taming the reactivity of monoterpene synthases to guide regioselective product hydroxylation ', ChemBioChem . https://doi.org/10.1002/cbic.201900672مصطلحات موضوعية: Stereochemistry, Terpenoids, Monoterpene, Cyclohexane Monoterpenes, Molecular dynamics, Molecular Dynamics Simulation, Protein Engineering, Hydroxylation, Biochemistry, enzyme catalysis, Enzyme catalysis, chemistry.chemical_compound, Residue (chemistry), Deprotonation, terpenoids, Manchester Institute of Biotechnology, Catalytic Domain, Intramolecular Lyases, Molecular Biology, Binding Sites, Eucalyptol, ATP synthase, biology, Full Paper, Organic Chemistry, Regioselectivity, Water, protein engineering, Stereoisomerism, Full Papers, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Terpenoid, molecular dynamics, Streptomyces, chemistry, Cyclization, biology.protein, Monoterpenes, Mutagenesis, Site-Directed, Molecular Medicine, Synthetic Biology, synthetic biology
وصف الملف: application/pdf
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14
المؤلفون: Inês S, Camacho, Rachelle, Black, Derren J, Heyes, Linus O, Johannissen, Lennart A I, Ramakers, Bruno, Bellina, Perdita E, Barran, Sam, Hay, Alex R, Jones
المصدر: Chemical Science
مصطلحات موضوعية: Chemistry, polycyclic compounds
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15
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16
المؤلفون: Bruno Bellina, Rachelle Black, Lennart A I Ramakers, Derren J. Heyes, Linus O. Johannissen, Alex R. Jones, Perdita E. Barran, Inês Camacho, Sam Hay
المصدر: Chemical Science
Camacho, I, Black, R, Heyes, D, Johannissen, L O, Ramakers, L A I, Bellina, B, Barran, P, Hay, S & Jones, A R 2021, ' Interplay Between Chromophore-Binding and Domain Assembly by the B12-Dependent Photoreceptor Protein, CarH ', Chemical Science . https://doi.org/10.1039/D1SC00522Gمصطلحات موضوعية: 0303 health sciences, ResearchInstitutes_Networks_Beacons/photon_science_institute, Dimer, 030302 biochemistry & molecular biology, Photoreceptor protein, General Chemistry, Chromophore, Photon Science Institute, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Protein–protein interaction, 03 medical and health sciences, chemistry.chemical_compound, Monomer, chemistry, Tetramer, Manchester Institute of Biotechnology, Biophysics, polycyclic compounds, DNA, Function (biology), 030304 developmental biology
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17
المؤلفون: Sam Hay, Linus O. Johannissen, Yiming Jin
المصدر: Jin, Y, Johannissen, L & Hay, S 2021, ' Predicting New Protein Conformations from Molecular Dynamics Simulation Conformational Landscapes and Machine Learning ', Proteins: structure, function, and bioinformatics . https://doi.org/10.1002/prot.26068
مصطلحات موضوعية: Protein structure and function, Computer science, Machine learning, computer.software_genre, Biochemistry, 03 medical and health sciences, Molecular dynamics, Matrix (mathematics), Structural Biology, Manchester Institute of Biotechnology, Conformational sampling, Molecular Biology, 030304 developmental biology, 0303 health sciences, Quantitative Biology::Biomolecules, Training set, business.industry, 030302 biochemistry & molecular biology, Sampling (statistics), ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Autoencoder, Range (mathematics), Principal component analysis, Artificial intelligence, business, computer
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18
المؤلفون: Derren J, Heyes, Shaowei, Zhang, Aoife, Taylor, Linus O, Johannissen, Samantha J O, Hardman, Sam, Hay, Nigel S, Scrutton
المصدر: Nature plants. 7(3)
مصطلحات موضوعية: Oxidoreductases Acting on CH-CH Group Donors, Structure-Activity Relationship, Light, Plant Development, Plants, Photochemical Processes, Catalysis, Plant Proteins
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19
المؤلفون: Thomas A. Jowitt, Shaowei Zhang, Linus O. Johannissen, Sam Hay, Nigel S. Scrutton, Samantha J. O. Hardman, Alan R.F. Godwin, Clair Baldock, Aoife Taylor, Derren J. Heyes
المصدر: Zhang, S, Godwin, A, Taylor, A, Hardman, S, Jowitt, T, Johannissen, L, Hay, S, Baldock, C, Heyes, D & Scrutton, N 2020, ' Dual Role of the Active Site ‘Lid’ Regions of Protochlorophyllide Oxidoreductase in Photocatalysis and Plant Development ', The FEBS Journal . https://doi.org/10.1111/febs.15542
مصطلحات موضوعية: 0301 basic medicine, Chlorophyll, Models, Molecular, Protein Conformation, alpha-Helical, Conformational change, Chloroplasts, Thermosynechococcus, Gene Expression, Crystallography, X-Ray, Biochemistry, Oligomer, Substrate Specificity, chemistry.chemical_compound, 0302 clinical medicine, Etioplast, Catalytic Domain, Histone octamer, Cloning, Molecular, Photosynthesis, chemistry.chemical_classification, biology, Chlorophyllides, Plants, Recombinant Proteins, Chloroplast, 030220 oncology & carcinogenesis, Hydrophobic and Hydrophilic Interactions, Protein Binding, Oxidoreductases Acting on CH-CH Group Donors, Genetic Vectors, 03 medical and health sciences, Protochlorophyllide, Oxidoreductase, Manchester Institute of Biotechnology, Escherichia coli, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, Sequence Homology, Amino Acid, Active site, Cell Biology, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Protein Structure, Tertiary, Kinetics, 030104 developmental biology, chemistry, Biophysics, biology.protein, Protein Conformation, beta-Strand, Protein Multimerization, Sequence Alignment, NADP
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20Academic Journal
المصدر: PLoS Biology, Vol 9, Iss 12, p e1001222 (2011)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource