المؤلفون: Ling-Hui Chou, Hsin-Lan Liu, Tsai-Hua Kao

المصدر: Journal of Functional Foods, Vol 27, Iss , Pp 150-159 (2016)

مصطلحات موضوعية: Luffa cylindrical peel, Micronization, Anti-inflammation, Functional components, Nutrition. Foods and food supply, TX341-641

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464616302754; https://doaj.org/toc/1756-4646

URL الوصول: https://doaj.org/article/e16863365a4347648d7ad93b713e5887

المؤلفون: Wen-Hsing Lin, Teng-Kuang Yeh, Weir-Torn Jiaang, Kuei-Jung Yen, Chun-Hwa Chen, Chin-Ting Huang, Shih-Chieh Yen, Shu-Yi Hsieh, Ling-Hui Chou, Ching-Ping Chen, Chun-Hsien Chiu, Li-Chun Kao, Yu-Sheng Chao, Chiung-Tong Chen, John T-A Hsu

المصدر: PLoS ONE, Vol 9, Iss 1, p e83160 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3885398?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e5078208d61149adbf9f92f8697b3132

المؤلفون: Ling-hui Chou, 周凌慧

Thesis Advisors: Meei Jyh Jiang, 江美治

وصف الملف: 65

الاتاحة: http://ndltd.ncl.edu.tw/handle/97671960153770666146

المؤلفون: Hsing Pang Hsieh, Pei-Chen Wang, Wan-Ching Yen, Kun-Hung Lee, Yu-Chen Huang, Chun-Yu Chang, Yu-Chieh Su, Chen-Ming Yang, You-Liang Lai, Wen-Hsing Lin, Chiung-Tong Chen, Chuan Shih, Teng-Kuang Yeh, Ling-Hui Chou, Cai-Syuan Wu

المصدر: Journal of Medicinal Chemistry. 64:14477-14497

مصطلحات موضوعية: Male, medicine.medical_treatment, Administration, Oral, Antineoplastic Agents, Receptor, Macrophage Colony-Stimulating Factor, Rats, Sprague-Dawley, Immunomodulating Agents, Mice, Structure-Activity Relationship, Cancer immunotherapy, Oral administration, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Animals, Receptor, Protein Kinase Inhibitors, IC50, Tumor microenvironment, Chemistry, Kinase, Neoplasms, Experimental, Mice, Inbred C57BL, Colonic Neoplasms, Cancer research, Molecular Medicine, Aurora Kinase B

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ca30e1530cdc6cc191b0eff08616e9
https://doi.org/10.1021/acs.jmedchem.1c01006

المؤلفون: Min-Hsien Wang, Tai-Yu Chiu, Teng-Kuang Yeh, Ching Ping Chen, Su-Wen Nieh, Chin-Yi Tsai, Chien Ho, Chiung-Tong Chen, Li Liu, Tsang-Wu Liu, Ying-Min Cheng, Ling-Hui Chou, Yen-Ju Chen

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

مصطلحات موضوعية: Paclitaxel, Immunology, Biological Availability, lcsh:Medicine, Antineoplastic Agents, Apoptosis, Breast Neoplasms, Article, Mice, chemistry.chemical_compound, Breast cancer, Cell Line, Tumor, Pancreatic cancer, medicine, Animals, Humans, Cytotoxic T cell, Cytotoxicity, lcsh:Science, Phospholipids, Cell Proliferation, Multidisciplinary, business.industry, lcsh:R, Mononuclear phagocyte system, medicine.disease, Xenograft Model Antitumor Assays, Immunity, Innate, Soybean Oil, Oxaliplatin, chemistry, Drug delivery, Toxicity, Cancer research, Heterografts, Nanoparticles, Emulsions, Female, lcsh:Q, Albumin-Bound Paclitaxel, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6bc8bd3acc121cbbf45242b1177de2
http://link.springer.com/article/10.1038/s41598-020-59813-7

المؤلفون: Hui-You Lin, Yi-Hui Peng, Kuo Wei Huang, Chen-Lung Huang, Mine-Hsine Wu, Chuan Shih, Teng-Kuang Yeh, Weir-Torn Jiaang, Ching-Chuan Kuo, Tsu Hsu, Ching-Ping Chen, Ya-Ling Weng, Chiung-Tong Chen, Fang-Chun Kung, Wen-Hsing Lin, Hui Yi Shiao, Jen-Shin Song, Ling-Hui Chou, Tsung-Sheng Wu, Kuei-Jung Yen, Pei-Chen Wang, Ching-Cheng Hsueh, Yu-Chieh Su, Cheng-Tai Lu, Hui-Jen Tsai, Su-Ying Wu, Li-Tzong Chen, Po-Chu Kuo

المصدر: Journal of Medicinal Chemistry. 62:11135-11150

مصطلحات موضوعية: Male, Stromal cell, Gastrointestinal Stromal Tumors, medicine.drug_class, Mice, Nude, Antineoplastic Agents, Apoptosis, Stem cell factor, Mice, SCID, Tyrosine-kinase inhibitor, Receptor tyrosine kinase, Rats, Sprague-Dawley, Mice, Mice, Inbred NOD, hemic and lymphatic diseases, Drug Discovery, Tumor Cells, Cultured, medicine, Animals, Humans, Phosphorylation, Kinase activity, Protein Kinase Inhibitors, neoplasms, Cell Proliferation, Gastrointestinal Neoplasms, Mice, Inbred ICR, biology, Chemistry, Kinase, Cell growth, Myeloid leukemia, Xenograft Model Antitumor Assays, digestive system diseases, Leukemia, Myeloid, Acute, Proto-Oncogene Proteins c-kit, Pyrimidines, fms-Like Tyrosine Kinase 3, Mutation, biology.protein, Cancer research, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60499fc4136ddd2d5cf080a65b7dda3b
https://doi.org/10.1021/acs.jmedchem.9b01229

المؤلفون: Kai-Chia Yeh, Min-Hsien Wang, Weir-Torn Jiaang, Chung-Yu Huang, Jen-Shin Song, Yu-Wen Huang, Chih-Bo Hu, Yu-Sheng Chao, Hsuan-Hui Ho, Chiung-Tong Chen, Tsu Hsu, Ling-Hui Chou, Teng-Kuang Yeh

المصدر: Life Sciences. 278:119574

مصطلحات موضوعية: Male, 0301 basic medicine, Pyrrolidines, Dipeptidyl Peptidase 4, medicine.medical_treatment, Administration, Oral, Mice, Obese, Dipeptidyl peptidase-4 inhibitor, Pharmacology, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Dipeptidyl peptidase, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, Species Specificity, Oral administration, Diabetes mellitus, Nitriles, Animals, Hypoglycemic Agents, Insulin, Medicine, General Pharmacology, Toxicology and Pharmaceutics, Dipeptidyl peptidase-4, Dipeptidyl-Peptidase IV Inhibitors, business.industry, Body Weight, General Medicine, Glucose Tolerance Test, medicine.disease, Metformin, Rats, Mice, Inbred C57BL, 030104 developmental biology, Tolerability, Area Under Curve, Hyperglycemia, Butanes, Jugular Veins, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8184d757fd23f1031063a1719cbc4add
https://doi.org/10.1016/j.lfs.2021.119574

المؤلفون: Tsai-Hua Kao, Hsin-Lan Liu, Ling-Hui Chou

المصدر: Journal of Functional Foods, Vol 27, Iss, Pp 150-159 (2016)

مصطلحات موضوعية: Necrosis, medicine.drug_class, Functional components, Medicine (miscellaneous), Anti-inflammatory, Nitric oxide, chemistry.chemical_compound, 0404 agricultural biotechnology, Anti-inflammation, medicine, TX341-641, Micronization, Prostaglandin E2, Luffa cylindrical peel, Oleanolic acid, Nutrition and Dietetics, Chromatography, Chemistry, Nutrition. Foods and food supply, Extraction (chemistry), 04 agricultural and veterinary sciences, 040401 food science, Liver function, medicine.symptom, Food Science, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ee1aba2c475ed556cd28891ace0ef6
http://www.sciencedirect.com/science/article/pii/S1756464616302754

المؤلفون: Kun-Hung Lee, Wan-Ching Yen, Wen-Hsing Lin, Pei-Chen Wang, You-Liang Lai, Yu-Chieh Su, Chun-Yu Chang, Cai-Syuan Wu, Yu-Chen Huang, Chen-Ming Yang, Ling-Hui Chou, Teng-Kuang Yeh, Chiung-Tong Chen, Chuan Shih, Hsing-Pang Hsieh

المصدر: Journal of Medicinal Chemistry; 10/14/2021, Vol. 64 Issue 19, p14477-14497, 21p

المؤلفون: Kuei Jung Yen, Tsu Hsu, Ling Hui Chou, Yu Ling Huang, Yu-Sheng Chao, H. Eugene Liu, Cheng Tai Lu, Teng Kuang Yeh, Weir-Torn Jiaang, Jen Shin Song, Chun Hwa Chen, Po Chu Kuo, Ching Ping Chen, Shih Chieh Yen, Chiung-Tong Chen, Wen-Hsing Lin, Chen Lung Huang, John T.A. Hsu

المصدر: European Journal of Medicinal Chemistry. 100:151-161

مصطلحات موضوعية: Male, Cell Survival, Mutant, Mice, Nude, Antineoplastic Agents, Drug resistance, Pyrazole, Pharmacology, Receptor tyrosine kinase, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, hemic and lymphatic diseases, Drug Discovery, Animals, Humans, Point Mutation, Protein Kinase Inhibitors, Cell Proliferation, Mice, Inbred ICR, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Point mutation, Organic Chemistry, Myeloid leukemia, Neoplasms, Experimental, General Medicine, Rats, Thiazoles, fms-Like Tyrosine Kinase 3, Drug Resistance, Neoplasm, Cell culture, biology.protein, Drug Screening Assays, Antitumor, FLT3 Inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b23817984e4202f9b481b6ab6ca61f
https://doi.org/10.1016/j.ejmech.2015.05.008

المؤلفون: Yung-Ning Yang, Wen-Hsing Lin, Ching-Ping Chen, Tsu Hsu, John T.A. Hsu, Weir-Torn Jiaang, Yu-Sheng Chao, Ching-Fang Yeh, Ling-Hui Chou, Chun-Hwa Chen, Teng-Kuang Yeh, Jen-Shin Song, Chiung-Tong Chen, Shu-Yi Hsieh, Cheng-Tai Lu, Ching-Hui Chiu, Shih-Chieh Yen, Ya-Ju Tseng, Kuei-Jung Yen

المصدر: Bioorganic & Medicinal Chemistry. 21:2856-2867

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Sensitivity and Specificity, Biochemistry, Receptor tyrosine kinase, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, fluids and secretions, In vivo, Cell Line, Tumor, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Urea, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, biology, Chemistry, Kinase, Organic Chemistry, Sulfonamide (medicine), Myeloid leukemia, hemic and immune systems, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Myeloid, Acute, Leukemia, fms-Like Tyrosine Kinase 3, Benzamides, embryonic structures, Fms-Like Tyrosine Kinase 3, biology.protein, Molecular Medicine, Pharmacophore, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40789ec034aee7931573505d93f593c
https://doi.org/10.1016/j.bmc.2013.03.083

المؤلفون: John T.A. Hsu, Teng-Kuang Yeh, Cheng-Tai Lu, Chun-Wha Chen, An-Huei Cheng, Chiung-Tong Chen, Yun-I Chang, Yu-Lin Huang, Ya-Ju Tseng, Kuei-Rong Yen, Shu-Yi Hsieh, Ling-Hui Chou, Yu-Sheng Chao, Tsu Hsu, Ching-Ping Chen, Shih-Chieh Yen, Wen-Hsing Lin, Weir-Torn Jiaang

المصدر: Bioorganic & Medicinal Chemistry. 19:4173-4182

مصطلحات موضوعية: Niacinamide, Sorafenib, Indazoles, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Receptor tyrosine kinase, Mice, Structure-Activity Relationship, fluids and secretions, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, Sulfonamides, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Cell growth, Drug discovery, Phenylurea Compounds, Benzenesulfonates, Organic Chemistry, Myeloid leukemia, Stereoisomerism, hemic and immune systems, Disease Models, Animal, fms-Like Tyrosine Kinase 3, Enzyme inhibitor, embryonic structures, Fms-Like Tyrosine Kinase 3, biology.protein, Pyrazoles, Molecular Medicine, Drug Screening Assays, Antitumor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdb4bf50ac42fe9d31018604f22eb6a
https://doi.org/10.1016/j.bmc.2011.06.016

المؤلفون: Li Wha Wu, Hua Lin Wu, Ling Hui Chou, I. Chung Lo, Guey Yueh Shi, Shu-Lin Liu, Tsun-Mei Lin, Meei Jyh Jiang

المصدر: Cardiovascular Research. 81:771-779

مصطلحات موضوعية: Male, Time Factors, Platelet-derived growth factor, Vascular smooth muscle, Physiology, Thrombomodulin, Myocytes, Smooth Muscle, Becaplermin, Transfection, Muscle, Smooth, Vascular, Proto-Oncogene Protein c-ets-1, Mice, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, Physiology (medical), Animals, Humans, RNA, Messenger, Extracellular Signal-Regulated MAP Kinases, Promoter Regions, Genetic, Protein kinase B, Cells, Cultured, PI3K/AKT/mTOR pathway, Platelet-Derived Growth Factor, biology, TOR Serine-Threonine Kinases, Proto-Oncogene Proteins c-sis, Recombinant Proteins, Up-Regulation, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, src-Family Kinases, chemistry, cardiovascular system, Cancer research, biology.protein, RNA Interference, Signal transduction, Carotid Artery Injuries, Cardiology and Cardiovascular Medicine, Protein Kinases, Proto-Oncogene Proteins c-akt, Platelet-derived growth factor receptor, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cda952452b03aaa72254bb9cba405f8
https://doi.org/10.1093/cvr/cvn351

المؤلفون: Weir-Torn Jiaang, Kuei-Rong Yen, Ling-Hui Chou, Wen-Hsing Lin, John T.A. Hsu, Ching-Hui Chiu, Teng-Kuang Yeh, Shih-Chieh Yen, Chiung-Tong Chen, Yun-I Chang, Shu-Yi Hsieh, Ya-Ju Tseng, Cheng-Tai Lu, Tsu Hsu, Chun-Hwa Chen, Yu-Sheng Chao

المصدر: Bioorganicmedicinal chemistry letters. 22(14)

مصطلحات موضوعية: Sorafenib, Carbamate, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Receptor tyrosine kinase, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Mouse xenograft, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Amines, Molecular Biology, Protein Kinase Inhibitors, biology, Molecular Structure, Organic Chemistry, Xenograft Model Antitumor Assays, chemistry, fms-Like Tyrosine Kinase 3, Fms-Like Tyrosine Kinase 3, ROR1, biology.protein, Molecular Medicine, Pyrazoles, Growth inhibition, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b769c3ce7c105355bef58ef547fc570a
https://pubmed.ncbi.nlm.nih.gov/22726931

المؤلفون: Kun-Hung Lee (11520724), Wan-Ching Yen (11520727), Wen-Hsing Lin (208256), Pei-Chen Wang (6575789), You-Liang Lai (11520730), Yu-Chieh Su (138988), Chun-Yu Chang (380014), Cai-Syuan Wu (11520733), Yu-Chen Huang (1926214), Chen-Ming Yang (542457), Ling-Hui Chou (507465), Teng-Kuang Yeh (208258), Chiung-Tong Chen (33535), Chuan Shih (1434997), Hsing-Pang Hsieh (139595)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Cancer, Chemical Sciences not elsewhere classified, molecular docking revealed, chain extension strategy, additional nonclassical hydrogen, >, oral administration, like macrophage survival, like macrophage growth, selective csf1r inhibitors, selective csf1r inhibitor, csf1r potency enhancement, csf1r hinge region, bpr1k871 (< b, aurora kinase b, 12 , immunosuppressive tumor microenvironment, 50 , vivo <, associated macrophage, b activities, unique 7, structural studies

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_BPR1R024_an_Orally_Active_and_Selective_CSF1R_Inhibitor_that_Exhibits_Antitumor_and_Immunomodulatory_Activity_in_a_Murine_Colon_Tumor_Model/16734940

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01006.s001

المؤلفون: I.-Chung Lo, Tsun-Mei Lin, Ling-Hui Chou, Shu-Lin Liu, Li-Wha Wu, Guey-Yueh Shi, Hua-Lin Wu, Meei Jyh Jiang

المصدر: Cardiovascular Research; Mar2009, Vol. 81 Issue 4, p771-771, 1p

مصطلحات موضوعية: THROMBOMODULIN, PLATELET-derived growth factor, VASCULAR smooth muscle, ANTICOAGULANTS, PHOSPHOINOSITIDES, RAPAMYCIN, GENE expression, GENETIC regulation