المؤلفون: McNamara, Case W, Lee, Marcus CS, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Nagle, Advait, Simon, Oliver, Yeung, Bryan KS, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, TR Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens HM, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A

المصدر: Nature. 504(7479)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Orphan Drug, Prevention, Infectious Diseases, Rare Diseases, Malaria, Vector-Borne Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, 1-Phosphatidylinositol 4-Kinase, Adenosine Triphosphate, Animals, Binding Sites, Cytokinesis, Drug Resistance, Fatty Acids, Female, Hepatocytes, Humans, Imidazoles, Life Cycle Stages, Macaca mulatta, Male, Models, Biological, Models, Molecular, Phosphatidylinositol Phosphates, Plasmodium, Pyrazoles, Quinoxalines, Reproducibility of Results, Schizonts, rab GTP-Binding Proteins, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/31f5h8fc

المؤلفون: Paquet, Tanya, Le Manach, Claire, Cabrera, Diego González, Younis, Yassir, Henrich, Philipp P., Abraham, Tara S., Lee, Marcus C.S., Basak, Rajshekhar, Ghidelli-Disse, Sonja, Lafuente-Monasterio, María José, Bantscheff, Marcus, Ruecker, Andrea, Blagborough, Andrew M., Zakutansky, Sara E., Zeeman, Anne Marie, White, Karen L., Shackleford, David M., Mannila, Janne, Morizzi, Julia, Scheurer, Christian, Angulo-Barturen, Iñigo, Santosmartínez, María, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Reader, Janette, Botha, Mariette, Dechering, Koen J., Sauerwein, Robert W., Tungtaeng, Anchalee, Vanachayangkul, Pattaraporn, Lim, Chek Shik, Burrows, Jeremy, Witty, Michael J., Marsh, Kennan C., Bodenreider, Christophe, Rochford, Rosemary, Solapure, Suresh M., Jiménez-Díaz, María Belén, Wittlin, Sergio, Charman, Susan A., Donini, Cristina, Campo, Brice, Birkholtz, Lyn Marie, Khanson, Kirsten, Drewes, Gerard, Kocken, Clemensh M., Delves, Michael J., Leroy, Didier, Fidock, David A., Waterson, David, Street, Leslie J., Chibale, Kelly

المصدر: Paquet , T , Le Manach , C , Cabrera , D G , Younis , Y , Henrich , P P , Abraham , T S , Lee , M C S , Basak , R , Ghidelli-Disse , S , Lafuente-Monasterio , M J , Bantscheff , M , Ruecker , A , Blagborough , A M , Zakutansky , S E , Zeeman , A M , White , K L , Shackleford , D M , Mannila , J , Morizzi , J , Scheurer , C , Angulo-Barturen , I , Santosmartínez , M ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/2700/2700, name=General Medicine

الاتاحة: https://discovery.dundee.ac.uk/en/publications/f96e07b3-664b-4f71-be9a-e8c29fb1c1d6
https://doi.org/10.1126/scitranslmed.aad9735
http://www.scopus.com/inward/record.url?scp=85018309975&partnerID=8YFLogxK

المؤلفون: Hoepfner, Dominic, McNamara, Case W., Lim, Chek Shik, Studer, Christian, Riedl, Ralph, Aust, Thomas, McCormack, Susan L., Plouffe, David M., Meister, Stephan, Schuierer, Sven, Plikat, Uwe, Hartmann, Nicole, Staedtler, Frank, Cotesta, Simona, Schmitt, Esther K., Petersen, Frank, Supek, Frantisek, Glynne, Richard J., Tallarico, John A., Porter, Jeffrey A., Fishman, Mark C., Bodenreider, Christophe, Diagana, Thierry T., Movva, N. Rao, Winzeler, Elizabeth A.

المصدر: Cell Host & Microbe ; volume 11, issue 6, page 654-663 ; ISSN 1931-3128

الاتاحة: http://dx.doi.org/10.1016/j.chom.2012.04.015
https://api.elsevier.com/content/article/PII:S1931312812001618?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1931312812001618?httpAccept=text/plain

المؤلفون: Paquet, Tanya, Le Manach, Claire, Cabrera, Diego González, Younis, Yassir, Henrich, Philipp P, Abraham, Tara S, Lee, Marcus CS, Basak, Rajshekhar, Ghidelli-Disse, Sonja, Lafuente-Monasterio, María José, Bantscheff, Marcus, Ruecker, Andrea, Blagborough, Andrew M, Zakutansky, Sara E, Zeeman, Anne-Marie, White, Karen L, Shackleford, David M, Mannila, Janne, Morizzi, Julia, Scheurer, Christian, Angulo-Barturen, Iñigo, Martínez, María Santos, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Reader, Janette, Botha, Mariette, Dechering, Koen J, Sauerwein, Robert W, Tungtaeng, Anchalee, Vanachayangkul, Pattaraporn, Lim, Chek Shik, Burrows, Jeremy, Witty, Michael J, Marsh, Kennan C, Bodenreider, Christophe, Rochford, Rosemary, Solapure, Suresh M, Jiménez-Díaz, María Belén, Wittlin, Sergio, Charman, Susan A, Donini, Cristina, Campo, Brice, Birkholtz, Lyn-Marie, Hanson, Kirsten K, Drewes, Gerard, Kocken, Clemens HM, Delves, Michael J, Leroy, Didier, Fidock, David A, Waterson, David, Street, Leslie J, Chibale, Kelly

Relation: Paquet, Tanya; Le Manach, Claire; Cabrera, Diego González; Younis, Yassir; Henrich, Philipp P; Abraham, Tara S; Lee, Marcus CS; Basak, Rajshekhar; Ghidelli-Disse, Sonja; Lafuente-Monasterio, María José; +43 more. Bantscheff, Marcus; Ruecker, Andrea; Blagborough, Andrew M; Zakutansky, Sara E; Zeeman, Anne-Marie; White, Karen L; Shackleford, David M; Mannila, Janne; Morizzi, Julia; Scheurer, Christian; Angulo-Barturen, Iñigo; Martínez, María Santos; Ferrer, Santiago; Sanz, Laura María; Gamo, Francisco Javier; Reader, Janette; Botha, Mariette; Dechering, Koen J; Sauerwein, Robert W; Tungtaeng, Anchalee; Vanachayangkul, Pattaraporn; Lim, Chek Shik; Burrows, Jeremy; Witty, Michael J; Marsh, Kennan C; Bodenreider, Christophe; Rochford, Rosemary; Solapure, Suresh M; Jiménez-Díaz, María Belén; Wittlin, Sergio; Charman, Susan A; Donini, Cristina; Campo, Brice; Birkholtz, Lyn-Marie; Hanson, Kirsten K; Drewes, Gerard; Kocken, Clemens HM; Delves, Michael J ; Leroy, Didier; Fidock, David A; Waterson, David; Street, Leslie J; Chibale, Kelly; (2016) Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Science translational medicine, 9 (387). eaad9735-eaad9735. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aad9735

الاتاحة: https://researchonline.lshtm.ac.uk/id/eprint/4648927/

المؤلفون: Zou, Bin, Nagle, Advait, Chatterjee, Arnab K., Leong, Seh Yong, Tan, Liying Jocelyn, Sim, Wei Lin Sandra, Mishra, Pranab, Guntapalli, Prasuna, Tully, David C., Lakshminarayana, Suresh B., Lim, Chek Shik, Tan, Yong Cheng, Abas, Siti Nurdiana, Bodenreider, Christophe, Kuhen, Kelli L., Gagaring, Kerstin, Borboa, Rachel, Chang, Jonathan, Li, Chun, Hollenbeck, Thomas, Tuntland, Tove, Zeeman, Anne-Marie, Kocken, Clemens H. M., McNamara, Case, Kato, Nobutaka, Winzeler, Elizabeth A., Yeung, Bryan K. S., Diagana, Thierry T., Smith, Paul W., Roland, Jason

المساهمون: Wellcome Trust, Medicines for Malaria Venture, Swiss Tropical and Public Health Institute

المصدر: ACS Medicinal Chemistry Letters ; volume 5, issue 8, page 947-950 ; ISSN 1948-5875 1948-5875

الاتاحة: http://dx.doi.org/10.1021/ml500244m
https://pubs.acs.org/doi/pdf/10.1021/ml500244m

المؤلفون: McNamara, Case W., Lee, Marcus C.S., Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Nagle, Advait, Simon, Oliver, Yeung, Bryan K.S., Chatterjee, Arnab K., McCormack, Susan L., Manary, Micah J., Zeeman, Anne-Marie, Dechering, Koen J., Kumar, T. R.Santha, Henrich, Philipp P., Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L., Fischli, Christoph, Rottmann, Matthias, Plouffe, David M., Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W., Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C., Kocken, Clemens H.M., Glynne, Richard J., Bodenreider, Christophe, Fidock, David A., Diagana, Thierry T., Winzeler, Elizabeth A.

المصدر: McNamara , C W , Lee , M C S , Lim , C S , Lim , S H , Roland , J , Nagle , A , Simon , O , Yeung , B K S , Chatterjee , A K , McCormack , S L , Manary , M J , Zeeman , A-M , Dechering , K J , Kumar , T R S , Henrich , P P , Gagaring , K , Ibanez , M , Kato , N , Kuhen , K L , Fischli , C , Rottmann , M , ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1000, name=General

الاتاحة: https://discovery.dundee.ac.uk/en/publications/f04d4073-90f4-420c-87a6-db9b11c170b1
https://doi.org/10.1038/nature12782
http://www.scopus.com/inward/record.url?scp=84890428942&partnerID=8YFLogxK

المؤلفون: Hoepfner, Dominic, McNamara, Case, Lim, Chek Shik, Studer, Christian, Riedl, Ralph, Aust, Thomas, McCormack, Susan L, Plouffe, David M, Schuierer, Sven, Plikat, Uwe, Hartmann, Nicole, Staedtler, Frank, Cotesta, Simona, Schmitt, Esther, Petersen, Frank, Supek, Frantisek, Glynne, Richard J, Tallarico, John, Porter, Jeffrey, Fishman, Mark, Bodenreider, Christophe, Diagana, Thierry Tidiane, Movva, Rao, Winzeler, Elizabeth A

Relation: Hoepfner, Dominic, McNamara, Case, Lim, Chek Shik, Studer, Christian, Riedl, Ralph, Aust, Thomas, McCormack, Susan L, Plouffe, David M, Schuierer, Sven, Plikat, Uwe, Hartmann, Nicole, Staedtler, Frank, Cotesta, Simona, Schmitt, Esther, Petersen, Frank, Supek, Frantisek, Glynne, Richard J, Tallarico, John, Porter, Jeffrey, Fishman, Mark, Bodenreider, Christophe, Diagana, Thierry Tidiane, Movva, Rao and Winzeler, Elizabeth A (2012) Cladosporin, a fungal metabolite with potent blood and hepatic stage antimalarial activity targets lysyl-tRNA synthetase. Cell Host & Microbe, 11 (6). pp. 654-663. ISSN 1931-3128; PMID: 22704625; doi:10.1016/j.chom.2012.04.015

الاتاحة: https://oak.novartis.com/4585/
http://www.cell.com/cell-host-microbe/

المؤلفون: Ravu, Vengala Rao, Leung, Gulice Y. C., Lim, Chek Shik, Ng, Sin Yee, Sum, Rong Ji, Chen, David Y.‐K.

المصدر: European Journal of Organic Chemistry ; volume 2011, issue 3, page 463-468 ; ISSN 1434-193X 1099-0690

الاتاحة: http://dx.doi.org/10.1002/ejoc.201001562
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fejoc.201001562
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ejoc.201001562/fullpdf

المؤلفون: Nicolaou, K. C., Kang, Qiang, Wu, T. Robert, Lim, Chek Shik, Chen, David Y.-K.

المصدر: Journal of the American Chemical Society ; volume 132, issue 21, page 7540-7548 ; ISSN 0002-7863 1520-5126

الاتاحة: http://dx.doi.org/10.1021/ja102623j
https://pubs.acs.org/doi/pdf/10.1021/ja102623j

المؤلفون: Nicolaou, K. C., Peng, Xiao‐Shui, Sun, Ya‐Ping, Polet, Damien, Zou, Bin, Lim, Chek Shik, Chen, David Y.‐K.

المصدر: ChemInform ; volume 41, issue 1 ; ISSN 0931-7597 1522-2667

الاتاحة: http://dx.doi.org/10.1002/chin.201001219
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.201001219
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.201001219

المؤلفون: Nicolaou, K. C., Peng, Xiao-Shui, Sun, Ya-Ping, Polet, Damien, Zou, Bin, Lim, Chek Shik, Chen, David Y.-K.

المصدر: Journal of the American Chemical Society ; volume 131, issue 30, page 10587-10597 ; ISSN 0002-7863 1520-5126

الاتاحة: http://dx.doi.org/10.1021/ja902939t
https://pubs.acs.org/doi/pdf/10.1021/ja902939t

المؤلفون: Nicolaou, K.C., Leung, Gulice Y. C., Dethe, Dattatraya H., Guduru, Ramakrishna, Sun, Ya-Ping, Lim, Chek Shik, Chen, David Y.-K.

المصدر: Journal of the American Chemical Society ; volume 130, issue 30, page 10019-10023 ; ISSN 0002-7863 1520-5126

الاتاحة: http://dx.doi.org/10.1021/ja802803e
https://pubs.acs.org/doi/pdf/10.1021/ja802803e

المؤلفون: Ravu, Vengala Rao, Leung, Gulice Y. C., Lim, Chek Shik, Ng, Sin Yee, Sum, Rong Ji, Chen, David Y.-K.

المصدر: European Journal of Organic Chemistry; Jan2011, Vol. 2011 Issue 3, p463-468, 6p

المؤلفون: LIM CHEK SHIK

المساهمون: BIOCHEMISTRY, CHANG CHAN FONG

مصطلحات موضوعية: CD38, CD-1, FAS, SREBP-1, cADPR, Lipid

Relation: LIM CHEK SHIK (2007-05-22). Possible role of CD38 in lipid homeostasis in the liver of CD-1 mice. ScholarBank@NUS Repository.; http://scholarbank.nus.edu.sg/handle/10635/23068; NOT_IN_WOS

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/23068

المؤلفون: Paquet, Tanya, Le Manach, Claire, Cabrera, Diego González, Younis, Yassir, Henrich, Philipp P., Abraham, Tara S., Lee, Marcus C. S., Basak, Rajshekhar, Ghidelli-Disse, Sonja, Lafuente-Monasterio, María José, Bantscheff, Marcus, Ruecker, Andrea, Blagborough, Andrew M., Zakutansky, Sara E., Zeeman, Anne-Marie, White, Karen L., Shackleford, David M., Mannila, Janne, Morizzi, Julia, Scheurer, Christian, Angulo-Barturen, Iñigo, Martínez, María Santos, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Reader, Janette, Botha, Mariette, Dechering, Koen J., Sauerwein, Robert W., Tungtaeng, Anchalee, Vanachayangkul, Pattaraporn, Lim, Chek Shik, Burrows, Jeremy, Witty, Michael J., Marsh, Kennan C., Bodenreider, Christophe, Rochford, Rosemary, Solapure, Suresh M., Jiménez-Díaz, María Belén, Wittlin, Sergio, Charman, Susan A., Donini, Cristina, Campo, Brice, Birkholtz, Lyn-Marie, Hanson, Kirsten K., Drewes, Gerard, Kocken, Clemens H. M., Delves, Michael J., Leroy, Didier, Fidock, David A., Waterson, David, Street, Leslie J., Chibale, Kelly

المصدر: Science Translational Medicine; April 2017, Vol. 9 Issue: 387

المؤلفون: Nicolaou, K. C., Peng, Xiao-Shui, Sun, Ya-Ping, Polet, Damien, Zou, Bin, Lim, Chek Shik, Chen, David Y.-K.

المصدر: ChemInform; Jan2010, Vol. 41 Issue 1, p-1, 1p