المؤلفون: Araldi, Dionéia, Sucher, Anatol, Kober, Kord, Ohara, Peter, Levine, Jon, Bogen, Oliver

مصطلحات موضوعية: Antisense oligonucleotides, Isolectin B4, hyperalgesic priming, ligand-conjugated antisense, nociceptors, pain, Rats, Animals, Lectins, Nociceptors, Streptavidin, Rats, Sprague-Dawley, Nerve Fibers, Unmyelinated, Oligonucleotides, Antisense, Ganglia, Spinal

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/83s1v8sz

المؤلفون: Baker, Brenda, Xia, Shuting, Partridge, Wesley, Kwoh, T, Tsimikas, Sotirios, Bhanot, Sanjay, Geary, Richard

المصدر: Nucleic Acid Therapeutics. 33(1)

مصطلحات موضوعية: integrated safety analysis, ligand-conjugated antisense technology, phase 2, randomized placebo-controlled trials, triantennary N-acetylgalactosamine, Humans, Oligonucleotides, Antisense, Ligands, Hepatocytes, Oligonucleotides, RNA

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/38g398k8
https://escholarship.org/content/qt38g398k8/qt38g398k8.pdf

المؤلفون: Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H. Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Infectious Diseases, Plant Biology, Space Science, Chemical Sciences not elsewhere classified, vhl ligand conjugated, target undruggable proteins, structural specificity intrinsic, positive immunological response, notably encompassing apoptosis, ingenious construct engendered, adenosine deaminase acting, specific target sequences, specific stress conditions, specific reader proteins, cancer cell death, protac likely elicits, protac design exhibits, selective degradation strategy, rna 1 given, cancer cells compared, binding protein adar1, based therapeutic modalities

Relation: https://figshare.com/articles/journal_contribution/Structurally_Specific_Z_DNA_Proteolysis_Targeting_Chimera_Enables_Targeted_Degradation_of_Adenosine_Deaminase_Acting_on_RNA_1/25391666

الاتاحة: https://doi.org/10.1021/jacs.3c13646.s001

المؤلفون: Viney, Nicholas J, Guo, Shuling, Tai, Li‐Jung, Baker, Brenda F, Aghajan, Mariam, Jung, Shiangtung W, Yu, Rosie Z, Booten, Sheri, Murray, Heather, Machemer, Todd, Burel, Sebastien, Murray, Sue, Buchele, Gustavo, Tsimikas, Sotirios, Schneider, Eugene, Geary, Richard S, Benson, Merrill D, Monia, Brett P

المصدر: ESC Heart Failure. 8(1)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Sciences, Cancer, Clinical Trials and Supportive Activities, Clinical Research, Liver Disease, Rare Diseases, Biotechnology, Orphan Drug, Digestive Diseases, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Amyloid Neuropathies, Familial, Animals, Ligands, Mice, Oligonucleotides, Antisense, Prealbumin, Transthyretin, Amyloidosis, Cardiomyopathy, Polyneuropathy, Antisense, Ligand-conjugated, Cardiorespiratory Medicine and Haematology, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/41n576q7

المؤلفون: Lim C, Shin Y, Kang K, Husni P, Lee D, Lee S, Choi HG, Lee ES, Youn YS, Oh KT

المصدر: International Journal of Nanomedicine, Vol Volume 18, Pp 1615-1630 (2023)

مصطلحات موضوعية: pegylated liposome, ligand-conjugated liposome, folate receptor, peg-linker length, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.dovepress.com/effects-of-peg-linker-chain-length-of-folate-linked-liposomal-formulat-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

URL الوصول: https://doaj.org/article/0e1fe626f38e4b70a24aafd36004da6c

المؤلفون: Annie Agnes Suganya Samson (14317492), Sandip Gangadhar Balwe (6276362), Sera Hong (9145521), Joon Myong Song (1533592)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Physiology, Cancer, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, three different sizes, terminated polyethylene glycol, sup >+, stabilized gold nanoparticles, quantitatively evaluated using, fabricated via temperature, small molecules showed, herg protein immunofluorescence, herg immunofluorescence compared, first report demonstrating, dependent human ether, channel block induced, surface ligand conjugated, channel block, surface ligands, herg proteins, first time, steric limitations, situ measurement, screening platform

Relation: https://figshare.com/articles/journal_contribution/Verification_of_Nanomaterial-Induced_Size-Dependent_Human_Ether-a_-Go-Go-Related_Gene_Potassium_Channel_Blockage_Using_Three-Dimensional_Bioengineered_Functional_Cardiac_Tissue_Constructs/21804181

الاتاحة: https://doi.org/10.1021/acs.chemmater.2c03249.s001

المؤلفون: Nicholas J. Viney, Shuling Guo, Li‐Jung Tai, Brenda F. Baker, Mariam Aghajan, Shiangtung W. Jung, Rosie Z. Yu, Sheri Booten, Heather Murray, Todd Machemer, Sebastien Burel, Sue Murray, Gustavo Buchele, Sotirios Tsimikas, Eugene Schneider, Richard S. Geary, Merrill D. Benson, Brett P. Monia

المصدر: ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)

مصطلحات موضوعية: Transthyretin, Amyloidosis, Cardiomyopathy, Polyneuropathy, Antisense, Ligand‐conjugated, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2055-5822

URL الوصول: https://doaj.org/article/3297462a8e6e4c1081fbb6040b37c72e

المؤلفون: Tae In Kim (3797209), Ick-Joon Park (1425010), Sumin Kang (2011621), Taek-Soo Kim (1425022), Sung-Yool Choi (1418842)

مصطلحات موضوعية: Biochemistry, Biotechnology, Space Science, Chemical Sciences not elsewhere classified, next-generation energy harvesting s., Enhanced Triboelectric Nanogenerator, alkane chain lengths, TMD-based TENG devices, ligand-conjugated TMD TENG device, TMD-to-polymer device geometries, 10 000 cycles, future triboelectric nanogenerators, output performance, thiolated ligand conjugation, p-type doping effect, novel defect engineering, ligand-conjugated TMD TENG device e., Thiolated Ligand Conjugation Two-di.

Relation: https://figshare.com/articles/journal_contribution/Enhanced_Triboelectric_Nanogenerator_Based_on_Tungsten_Disulfide_via_Thiolated_Ligand_Conjugation/14509357

الاتاحة: https://doi.org/10.1021/acsami.1c02562.s001

المؤلفون: Jorge Losada Méndez (11681212), Francisca Palomares (1525033), Francisca Gómez (11681215), Pedro Ramírez-López (1894933), Javier Ramos-Soriano (4818504), Maria Jose Torres (2200033), Cristobalina Mayorga (458863), Javier Rojo (1525024)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Cancer, Plant Biology, Chemical Sciences not elsewhere classified, synthesized two family, pyrimido ­[ 5, pru p 3, lipid transfer protein, food allergy immunotherapy, dependent food allergy, peach allergic patients, tlr7 ligand conjugated, specific maturation, safety compounds, powerful strategy, potential application, oxoadenine derivative, like receptor, immunomodulatory response, dendritic cells, cytokine production, could induce, conjugates interact, cell proliferation

Relation: https://figshare.com/articles/journal_contribution/Immunomodulatory_Response_of_Toll-like_Receptor_Ligand_Peptide_Conjugates_in_Food_Allergy/16989682

الاتاحة: https://doi.org/10.1021/acschembio.1c00765.s001

المؤلفون: Viney, Nicholas J., Guo, Shuling, Tai, Li-Jung, Baker, Brenda F., Aghajan, Mariam, Jung, Shiangtung W., Yu, Rosie Z., Booten, Sheri, Murray, Heather, Machemer, Todd, Burel, Sebastien, Murray, Sue, Buchele, Gustavo, Tsimikas, Sotirios, Schneider, Eugene, Geary, Richard S., Benson, Merrill D., Monia, Brett P.

المساهمون: Medicine, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Amyloidosis, Antisense, Cardiomyopathy, Ligand-conjugated, Polyneuropathy, Transthyretin

وصف الملف: application/pdf

Relation: ESC Heart Failure; Viney NJ, Guo S, Tai LJ, et al. Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data. ESC Heart Fail. 2021;8(1):652-661. doi:10.1002/ehf2.13154; https://hdl.handle.net/1805/42746

الاتاحة: https://hdl.handle.net/1805/42746

المؤلفون: Sheri L. Booten, Gustavo Buchele, Mariam Aghajan, Todd Machemer, Brett P. Monia, Richard S. Geary, Nicholas J. Viney, Sue Murray, Merrill D. Benson, Sebastien A. Burel, Sotirios Tsimikas, Shuling Guo, Eugene Schneider, Shiangtung W. Jung, Brenda F. Baker, Heather M. Murray, Li-Jung Tai, Rosie Z. Yu

المصدر: ESC heart failure, vol 8, iss 1
ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)
ESC Heart Failure

مصطلحات موضوعية: lcsh:Diseases of the circulatory (Cardiovascular) system, Oligonucleotides, 030204 cardiovascular system & hematology, Pharmacology, Cardiorespiratory Medicine and Haematology, Amyloid Neuropathies, Ligands, Transthyretin, Mice, 0302 clinical medicine, Familial, Ligand-conjugated, Original Research Articles, Clinical endpoint, Medicine, Prealbumin, Original Research Article, 030212 general & internal medicine, Cancer, biology, Amyloidosis, Liver Disease, Tolerability, 6.1 Pharmaceuticals, Cardiology and Cardiovascular Medicine, Polyneuropathy, Biotechnology, endocrine system, Cardiomyopathy, Clinical Trials and Supportive Activities, 03 medical and health sciences, Rare Diseases, Pharmacokinetics, Clinical Research, Potency, Animals, Antisense, Adverse effect, Amyloid Neuropathies, Familial, business.industry, Ligand‐conjugated, nutritional and metabolic diseases, Evaluation of treatments and therapeutic interventions, Oligonucleotides, Antisense, medicine.disease, Orphan Drug, lcsh:RC666-701, biology.protein, business, Digestive Diseases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff308bcce12264c19717432639a3fe9f
https://escholarship.org/uc/item/41n576q7

المؤلفون: Minoru Takahashi, Yasushi Sato, Yoshiro Niitsu, 佐藤 康史, 新津 洋司郎, 高橋 稔

المصدر: Drug Delivery System. 2000, 15(1):32

المؤلفون: Miaozhong Ni, Xinchao Zhang, Guoping Cai, Huaiwen Chen, Qingmin Zeng, Min Xiong, Zuochong Yu

المصدر: International Journal of Nanomedicine

مصطلحات موضوعية: Materials science, Biophysics, Pharmaceutical Science, Bioengineering, Biomaterials, Mice, chemistry.chemical_compound, Polylactic Acid-Polyglycolic Acid Copolymer, Antigens, CD, cancer initiating cells, International Journal of Nanomedicine, Cancer stem cell, In vivo, Cell Line, Tumor, parasitic diseases, Drug Discovery, medicine, Animals, AC133 Antigen, Lactic Acid, Cytotoxicity, neoplasms, Salinomycin, Glycoproteins, Pyrans, Original Research, Osteosarcoma, Organic Chemistry, ligand-conjugated nanomedicines, General Medicine, Aptamers, Nucleotide, targeted therapy, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Rats, chemistry, Biochemistry, Drug delivery, Neoplastic Stem Cells, Cancer research, Nanoparticles, Stem cell, Peptides, Polyglycolic Acid

وصف الملف: text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c348e3e9e6b7a458e4ffaa2556e813d7
https://doi.org/10.2147/ijn.s78498