المؤلفون: Lieberman, Mackenzie M., Tong, Jason H., Odukwe, Nkechi U., Chavel, Colin A., Purdon, Terence J., Burchett, Rebecca, Gillard, Bryan M., Brackett, Craig M., McGray, A. J. Robert, Bramson, Jonathan L., Brentjens, Renier J., Lee, Kelvin P., Olejniczak, Scott H.

المساهمون: Medicine, School of Medicine

المصدر: PMC

مصطلحات موضوعية: CD28, Co-stimulation, CAR T cells, Multiple myeloma, Tumor microenvironment, Metabolism

وصف الملف: application/pdf

Relation: Lieberman MM, Tong JH, Odukwe NU, et al. Endogenous CD28 drives CAR T cell responses in multiple myeloma. Preprint. bioRxiv. 2024;2024.03.21.586084. Published 2024 Apr 9. doi:10.1101/2024.03.21.586084; https://hdl.handle.net/1805/42138

الاتاحة: https://hdl.handle.net/1805/42138

المؤلفون: Holling, G. Aaron, Chavel, Colin A., Sharda, Anand P., Lieberman, Mackenzie M., James, Caitlin M., Lightman, Shivana M., Tong, Jason H., Qiao, Guanxi, Emmons, Tiffany R., Giridharan, Thejaswini, Hou, Shengqi, Intlekofer, Andrew M., Higashi, Richard M., Fan, Teresa W. M., Lane, Andrew N., Eng, Kevin H., Segal, Brahm H., Repasky, Elizabeth A., Lee, Kelvin P., Olejniczak, Scott H.

المساهمون: Medicine, School of Medicine

المصدر: PMC

مصطلحات موضوعية: ARS2, CD8 T cells, Immunometabolism, PKM2, mRNA splicing

وصف الملف: application/pdf

Relation: Cellular & Molecular Immunology; Holling GA, Chavel CA, Sharda AP, et al. CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis-driven alternative splicing of PKM supports antitumor immunity. Cell Mol Immunol. 2024;21(3):260-274. doi:10.1038/s41423-024-01124-2; https://hdl.handle.net/1805/41791

الاتاحة: https://hdl.handle.net/1805/41791