المؤلفون: Licia Totani, Concetta Amore, Antonio Piccoli, Giuseppe Dell’Elba, Angelo Di Santo, Roberto Plebani, Romina Pecce, Nicola Martelli, Alice Rossi, Serena Ranucci, Ida De Fino, Paolo Moretti, Alessandra Bragonzi, Mario Romano, Virgilio Evangelista

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: cystic fibrosis, neutrophil, neutrophil extracellular traps, lung damage, PDE4 inhibition, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.702677/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/ca1fa9b109974680beb3ba1817622c98

المؤلفون: Diego O Croci, Albana Cumashi, Natalia A Ushakova, Marina E Preobrazhenskaya, Antonio Piccoli, Licia Totani, Nadezhda E Ustyuzhanina, Maria I Bilan, Anatolii I Usov, Alexey A Grachev, Galina E Morozevich, Albert E Berman, Craig J Sanderson, Maeve Kelly, Patrizia Di Gregorio, Cosmo Rossi, Nicola Tinari, Stefano Iacobelli, Gabriel A Rabinovich, Nikolay E Nifantiev, Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO), Italy

المصدر: PLoS ONE, Vol 6, Iss 2, p e17283 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3046160?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/81db8383eece4973aaf03285706bf918

المؤلفون: Roberto Plebani, Giuseppe Dell'Elba, Allesandra Bragonzi, Mario R. Romano, Virgilio Evangelista, Angelo Di Santo, Antonio Piccoli, Licia Totani, Nicola Martelli, Paolo Moretti, Alice Rossi, Serena Ranucci, C. Amore, Romina Pecce, Ida De Fino

مصطلحات موضوعية: COPD, Lung, business.industry, Phosphodiesterase, Inflammation, medicine.disease, Cystic fibrosis, Blockade, medicine.anatomical_structure, In vivo, Immunology, medicine, medicine.symptom, business, Roflumilast, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::836310ddfa2ecaba657984a2085464ae
https://doi.org/10.22541/au.161700109.94909942/v1

المؤلفون: Licia Totani (355328), Concetta Amore (11405840), Antonio Piccoli (355327), Giuseppe Dell’Elba (11405843), Angelo Di Santo (11405846), Roberto Plebani (11405849), Romina Pecce (11405852), Nicola Martelli (613866), Alice Rossi (365502), Serena Ranucci (9452285), Ida De Fino (168422), Paolo Moretti (218363), Alessandra Bragonzi (108447), Mario Romano (3854716), Virgilio Evangelista (155887)

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, cystic fibrosis, neutrophil, neutrophil extracellular traps, lung damage, PDE4 inhibition

Relation: https://figshare.com/articles/figure/Image1_Type-4_Phosphodiesterase_PDE4_Blockade_Reduces_NETosis_in_Cystic_Fibrosis_TIFF/16585364

الاتاحة: https://doi.org/10.3389/fphar.2021.702677.s002

المؤلفون: Licia Totani (355328), Concetta Amore (11405840), Antonio Piccoli (355327), Giuseppe Dell’Elba (11405843), Angelo Di Santo (11405846), Roberto Plebani (11405849), Romina Pecce (11405852), Nicola Martelli (613866), Alice Rossi (365502), Serena Ranucci (9452285), Ida De Fino (168422), Paolo Moretti (218363), Alessandra Bragonzi (108447), Mario Romano (3854716), Virgilio Evangelista (155887)

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, cystic fibrosis, neutrophil, neutrophil extracellular traps, lung damage, PDE4 inhibition

Relation: https://figshare.com/articles/dataset/DataSheet1_Type-4_Phosphodiesterase_PDE4_Blockade_Reduces_NETosis_in_Cystic_Fibrosis_docx/16585361

الاتاحة: https://doi.org/10.3389/fphar.2021.702677.s001

المؤلفون: Licia Totani, Concetta Amore, Antonio Piccoli, Giuseppe Dell’Elba, Angelo Di Santo, Roberto Plebani, Romina Pecce, Nicola Martelli, Alice Rossi, Serena Ranucci, Ida De Fino, Paolo Moretti, Alessandra Bragonzi, Mario Romano, Virgilio Evangelista

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, cystic fibrosis, neutrophil, neutrophil extracellular traps, lung damage, PDE4 inhibition

Relation: https://figshare.com/articles/figure/Image3_Type-4_Phosphodiesterase_PDE4_Blockade_Reduces_NETosis_in_Cystic_Fibrosis_TIFF/16585370

الاتاحة: https://doi.org/10.3389/fphar.2021.702677.s004
https://figshare.com/articles/figure/Image3_Type-4_Phosphodiesterase_PDE4_Blockade_Reduces_NETosis_in_Cystic_Fibrosis_TIFF/16585370

المؤلفون: Antonio Piccoli, Licia Totani, C. Amore, Nicola Martelli, A. Di Santo, V. Evangelista, H. Tenor, R. Beume, Giuseppe Dell'Elba

المصدر: Journal of Thrombosis and Haemostasis. 14:191-204

مصطلحات موضوعية: Blood Platelets, Cyclopropanes, Risk, 0301 basic medicine, P-selectin, Neutrophils, Aminopyridines, Macrophage-1 Antigen, Pharmacology, Extracellular Traps, Monocytes, Thromboplastin, Mice, Phosphatidylinositol 3-Kinases, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, Tissue factor, Platelet Adhesiveness, Leukocytes, medicine, Animals, Humans, Phosphorylation, Protein kinase B, Roflumilast, Microscopy, Confocal, business.industry, Fibrinogen, Phosphodiesterase, Thrombosis, Hematology, Neutrophil extracellular traps, Cyclic Nucleotide Phosphodiesterases, Type 4, P-Selectin, 030104 developmental biology, Cardiovascular Diseases, Macrophage-1 antigen, Benzamides, Immunology, Phosphodiesterase 4 Inhibitors, Signal transduction, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e908a082a77d94d571583d24b845dfab
https://doi.org/10.1111/jth.13173

المؤلفون: Lorenzo Federico, Antonio Piccoli, Giuseppe Dell'Elba, Nicola Martelli, Zehra Pamuklar, Amore Concetta, Virgilio Evangelista, Susan S. Smyth, Licia Totani, Angelomaria Di Santo

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 34:1689-1696

مصطلحات موضوعية: Blood Platelets, Time Factors, 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone, Neutrophils, Macrophage-1 Antigen, Biology, Article, Mice, Platelet Adhesiveness, Animals, Humans, Src family kinase, Phosphorylation, Protein kinase A, Mice, Knockout, Kinase, Phosphodiesterase, Vascular System Injuries, Focal Adhesion Kinase 2, Cyclic AMP-Dependent Protein Kinases, Cell biology, Femoral Artery, Disease Models, Animal, P-Selectin, src-Family Kinases, Neutrophil Infiltration, Tyrosine kinase 2, Phosphodiesterase 4 Inhibitors, Signal transduction, Cardiology and Cardiovascular Medicine, Rolipram, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d41f40d310838813b623e1d2a02b99
https://doi.org/10.1161/atvbaha.114.303939

المؤلفون: Licia Totani, V. Evangelista, Angelo A. Manfredi, Norma Maugeri

المصدر: Platelets in Thrombotic and Non-Thrombotic Disorders ISBN: 9783319474601

مصطلحات موضوعية: 0301 basic medicine, Innate immune system, biology, business.industry, Inflammation, Cystic fibrosis transmembrane conductance regulator, 03 medical and health sciences, Tissue factor, 030104 developmental biology, 0302 clinical medicine, Immune system, Hemostasis, Large vessel vasculitis, Immunology, biology.protein, Medicine, Platelet, medicine.symptom, business, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9b88f4f76c9f83cb63a3e369ee4ebe59
https://doi.org/10.1007/978-3-319-47462-5_30

المؤلفون: Licia Totani, Virgilio Evangelista, Luigia Di Francesco, Emanuela Marcantoni, Paola Patrignani, Antonio Piccoli, Stefania Tacconelli

المصدر: Prostaglandins & Other Lipid Mediators. 98:122-128

مصطلحات موضوعية: medicine.medical_specialty, Endothelium, Physiology, Prostaglandin, Prostacyclin, Biochemistry, Gene Expression Regulation, Enzymologic, Umbilical vein, chemistry.chemical_compound, Internal medicine, Human Umbilical Vein Endothelial Cells, medicine, Humans, RNA, Messenger, Pharmacology, biology, Prostanoid, Estrogens, Cell Biology, Vasoprotective, Heme oxygenase, Endocrinology, medicine.anatomical_structure, chemistry, Cyclooxygenase 2, Prostaglandins, cardiovascular system, biology.protein, Stress, Mechanical, Cyclooxygenase, Heme Oxygenase-1, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2f51259e6bd5da16cc57e9f1c69ea9
https://doi.org/10.1016/j.prostaglandins.2012.01.006

المؤلفون: Antonio Piccoli, Nicola Martelli, C. Amore, Giuseppe Dell'Elba, Licia Totani, Angelomaria Di Santo, Virgilio Evangelista

المصدر: Thrombosis and Haemostasis. 107:1130-1140

مصطلحات موضوعية: Blood Platelets, Male, Prasugrel, Platelet Function Tests, P-selectin, Anti-Inflammatory Agents, Down-Regulation, Macrophage-1 Antigen, Thiophenes, 030204 cardiovascular system & hematology, Pharmacology, Nitric Oxide, Piperazines, Mice, 03 medical and health sciences, chemistry.chemical_compound, Platelet Adhesiveness, 0302 clinical medicine, Selenoprotein P, Platelet adhesiveness, Leukocytes, medicine, Animals, Humans, Platelet, 030212 general & internal medicine, Platelet activation, Aspirin, Tumor Necrosis Factor-alpha, Hematology, Shock, Septic, Mice, Inbred C57BL, Thromboxane B2, Disease Models, Animal, chemistry, Immunology, Purinergic P2Y Receptor Antagonists, Platelet aggregation inhibitor, Inflammation Mediators, Prasugrel Hydrochloride, Biomarkers, Platelet Aggregation Inhibitors, Ex vivo, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2578bc7658f66b572d37b46814ef6622
https://doi.org/10.1160/th11-12-0867

المؤلفون: G. Iacuitti, Giuseppe Marelli, G. De Simone, Licia Totani, Elisa Nada, C. Amore, Stefano Manarini, Antonio Nicolucci, G. Levantesi, G Pozzoli, P. Di Summa, L. Brero, G. De Berardis, V. Evangelista, Fausto Avanzini, Ausilia Maione, Carlo Giorda, Giuseppe Dell'Elba, M. Pupillo, R. Pecce, G. Tognoni

المصدر: Journal of Thrombosis and Haemostasis. 5:2197-2203

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Urinary system, Type 2 diabetes, Thromboxane A2, chemistry.chemical_compound, Internal medicine, Diabetes mellitus, medicine, Humans, Platelet activation, Glycemic, Inflammation, Creatinine, Aspirin, medicine.diagnostic_test, business.industry, Hematology, Platelet Activation, medicine.disease, Endocrinology, Diabetes Mellitus, Type 2, chemistry, Glycemic Index, Case-Control Studies, Lipid profile, business, Biomarkers, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f7c55926fea828ed1e2739b8883621
https://doi.org/10.1111/j.1538-7836.2007.02728.x

المؤلفون: Romina Pecce, Giorgio Berton, Nicola Martelli, Clifford A. Lowell, Chiara Cerletti, Virgilio Evangelista, Lorenzo Federico, P Piccardoni, Licia Totani, Susan S. Smyth, Stefano Manarini, Antonio Piccoli

المصدر: Biochemical Journal. 396:89-98

مصطلحات موضوعية: Neutrophils, Recombinant Fusion Proteins, Integrin, PTK2, CHO Cells, Transfection, Biochemistry, Focal adhesion, Mice, chemistry.chemical_compound, Cricetulus, Cricetinae, E-selectin, Cell Adhesion, Animals, Humans, Phosphorylation, Cell adhesion, Egtazic Acid, Molecular Biology, Mice, Knockout, biology, Kinase, Tyrosine phosphorylation, Cell Biology, Focal Adhesion Kinase 2, Flow Cytometry, Molecular biology, Mice, Inbred C57BL, Pyrimidines, src-Family Kinases, chemistry, CD18 Antigens, biology.protein, Pyrazoles, Stress, Mechanical, E-Selectin, Rheology, Protein Processing, Post-Translational, Signal Transduction, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664739ec00bbd6c2350155a21c96c921
https://doi.org/10.1042/bj20051924

المؤلفون: Licia Totani, Antonio Piccoli, Nicola Martelli, Zsuzsa Bagoly, Romina Pecce, Virgilio Evangelista, Stefano Manarini, Lorenzo Federico, Chiara Cerletti, P Piccardoni

المصدر: Biochemical Journal. 380:57-65

مصطلحات موضوعية: Adult, Neutrophils, Integrin, Macrophage-1 Antigen, Biology, Biochemistry, SH3 domain, LYN, Cell Adhesion, Humans, Elméleti orvostudományok, Enzyme Inhibitors, Phosphorylation, Phosphotyrosine, Molecular Biology, Cells, Cultured, Tyrosine-protein kinase CSK, Kinase, Interleukin-8, Antibodies, Monoclonal, Orvostudományok, Cell Biology, Protein-Tyrosine Kinases, Flow Cytometry, Actins, Lymphocyte Function-Associated Antigen-1, Cell biology, Enzyme Activation, P-Selectin, Focal Adhesion Kinase 2, biology.protein, Stress, Mechanical, Protein Processing, Post-Translational, Tyrosine kinase, Research Article, Proto-oncogene tyrosine-protein kinase Src

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d5d1c57a25e794c77fb0b60a193d93
https://doi.org/10.1042/bj20040151

المؤلفون: Antonio Piccoli, Licia Totani, Rita Sideri, Nicola Martelli, Dietmar Vestweber, Serenella Rotondo, Virgilio Evangelista, Giovanni de Gaetano, Chiara Cerletti, P Piccardoni, S. Manarini

المصدر: Blood. 93:876-885

مصطلحات موضوعية: biology, Chemistry, medicine.drug_class, Cell adhesion molecule, Immunology, Integrin, hemic and immune systems, Tyrosine phosphorylation, Cell Biology, Hematology, Biochemistry, Tyrosine-kinase inhibitor, Cell biology, chemistry.chemical_compound, biology.protein, medicine, Phosphorylation, Platelet activation, Tyrosine, Tyrosine kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a6a4ba685fc6024ca287787256a649f0
https://doi.org/10.1182/blood.v93.3.876

المؤلفون: A. Piccoli, Licia Totani, A. Cumashi, Roberto Lorenzet

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 18:1534-1540

مصطلحات موضوعية: medicine.medical_specialty, Cathepsin G, Serine Proteinase Inhibitors, Platelet-derived growth factor, Endothelium, Neutrophils, medicine.medical_treatment, CD18, Biology, Umbilical vein, Mice, chemistry.chemical_compound, Internal medicine, medicine, Animals, Humans, Cells, Cultured, Platelet-Derived Growth Factor, Pancreatic Elastase, Cell adhesion molecule, Growth factor, Serine Endopeptidases, 3T3 Cells, Intercellular Adhesion Molecule-1, Cathepsins, Molecular biology, Coculture Techniques, Endothelial stem cell, Endocrinology, medicine.anatomical_structure, chemistry, cardiovascular system, Endothelium, Vascular, Mitogens, Cardiology and Cardiovascular Medicine, Interleukin-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346dd96a75cbff1e782dd9671eb13c06
https://doi.org/10.1161/01.atv.18.10.1534

المؤلفون: A. Piccoli, G Pellegrini, Licia Totani, A. Di Santo, Roberto Lorenzet

المصدر: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 14:125-132

مصطلحات موضوعية: Cathepsin G, Cell Survival, Neutrophils, Swine, medicine.medical_treatment, Basic fibroblast growth factor, Biology, Cycloheximide, chemistry.chemical_compound, medicine, Animals, Humans, Protease Inhibitors, Growth Substances, Aorta, Cells, Cultured, Platelet-Derived Growth Factor, Pancreatic Elastase, Cell growth, Growth factor, Serine Endopeptidases, Elastase, Free Radical Scavengers, Cathepsins, Molecular biology, N-Formylmethionine Leucyl-Phenylalanine, Endothelial stem cell, chemistry, Cell culture, Immunology, Fibroblast Growth Factor 2, Endothelium, Vascular, Reactive Oxygen Species, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9028e7af215e96186ff35228fe6ff326
https://doi.org/10.1161/01.atv.14.1.125

المؤلفون: Maria Teresa Tacconi, Licia Totani, Roberto Lorenzet, Angelomaria Di Santo, Antonio Piccoli, Maria Benedetta Donati, G Pellegrini

المصدر: Thrombosis Research. 71:95-101

مصطلحات موضوعية: Adult, Blood Platelets, Lipopolysaccharides, Male, chemistry.chemical_classification, Chemistry, Cell Membrane, Plasma composition, Biological activity, Hematology, Fish oil, Peripheral blood mononuclear cell, Thromboplastin, Membrane, Dietary Fats, Unsaturated, Biochemistry, Fatty Acids, Unsaturated, Leukocytes, Mononuclear, Humans, Female, Platelet, Polyunsaturated fatty acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8bba437e656c642a750cc7ad2fec9a
https://doi.org/10.1016/0049-3848(93)90209-7

المؤلفون: Licia Totani, Virgilio Evangelista

مصطلحات موضوعية: Blood Platelets, Intimal hyperplasia, Anti-Inflammatory Agents, Inflammation, Adaptive Immunity, Article, Pathogenesis, Immune system, Platelet Adhesiveness, Platelet adhesiveness, Immunopathology, Leukocytes, Medicine, Humans, business.industry, Acquired immune system, medicine.disease, Immunity, Innate, Cardiovascular Diseases, Immunology, Signal transduction, medicine.symptom, Inflammation Mediators, Cardiology and Cardiovascular Medicine, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05398bcefe97a78617b1872ee8fda5d
https://europepmc.org/articles/PMC3076621/

المؤلفون: Luigia Di Francesco, Licia Totani, Melania Dovizio, Antonio Piccoli, Andrea Di Francesco, Ryan A. Dercho, Francesca Seta, Assunta Pandolfi, Virgilio Evangelista, Paola Patrignani, Tania Salvatore

المصدر: Circulation research. 104(4)

مصطلحات موضوعية: medicine.medical_specialty, Physiology, medicine.medical_treatment, Receptors, Prostaglandin, Down-Regulation, Prostacyclin, 6-Ketoprostaglandin F1 alpha, Dinoprost, Receptors, Epoprostenol, Umbilical vein, Dinoprostone, chemistry.chemical_compound, Internal medicine, medicine, Humans, Cyclooxygenase Inhibitors, Heme, Cells, Cultured, Nitrobenzenes, Benzofurans, Inflammation, Sulfonamides, biology, Aspirin, Prostaglandin D2, Tumor Necrosis Factor-alpha, Endothelial Cells, Atherosclerosis, Molecular biology, Epoprostenol, Up-Regulation, Heme oxygenase, Endothelial stem cell, Perfusion, Cytokine, Endocrinology, chemistry, Cyclooxygenase 2, biology.protein, Cyclooxygenase 1, Tumor necrosis factor alpha, Cyclooxygenase, Stress, Mechanical, Propionates, Cardiology and Cardiovascular Medicine, Heme Oxygenase-1, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7345a39352f4479f289157a29533ba
https://pubmed.ncbi.nlm.nih.gov/19122175