المؤلفون: Beitler, Jeremy R, Thompson, B Taylor, Baron, Rebecca M, Bastarache, Julie A, Denlinger, Loren C, Esserman, Laura, Gong, Michelle N, LaVange, Lisa M, Lewis, Roger J, Marshall, John C, Martin, Thomas R, McAuley, Daniel F, Meyer, Nuala J, Moss, Marc, Reineck, Lora A, Rubin, Eileen, Schmidt, Eric P, Standiford, Theodore J, Ware, Lorraine B, Wong, Hector R, Aggarwal, Neil R, Calfee, Carolyn S

المصدر: The Lancet Respiratory Medicine. 10(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Rare Diseases, Orphan Drug, Lung, Acute Respiratory Distress Syndrome, Respiratory, Good Health and Well Being, COVID-19, Humans, Precision Medicine, Respiratory Distress Syndrome, Public Health and Health Services, Other Medical and Health Sciences, Cardiovascular medicine and haematology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/90r7n5vp

المؤلفون: VanBuren, John M, Casper, T Charles, Nishijima, Daniel K, Kuppermann, Nathan, Lewis, Roger J, Dean, J Michael, McGlothlin, Anna

المصدر: Trials. 22(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Traumatic Head and Spine Injury, Clinical Research, Childhood Injury, Physical Injury - Accidents and Adverse Effects, Women's Health, Pediatric, Neurosciences, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Injuries and accidents, Antifibrinolytic Agents, Bayes Theorem, Child, Double-Blind Method, Hemorrhage, Humans, Tranexamic Acid, Trauma Severity Indices, Wounds and Injuries, Bayesian statistics, Tranexamic acid, Pediatrics, Adaptive clinical trial design, Response-adaptive randomization, Dose-response, Trauma, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, General & Internal Medicine, Clinical sciences, Epidemiology, Health services and systems

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/26790063
https://escholarship.org/content/qt26790063/qt26790063.pdf

المؤلفون: Goligher, Ewan C, Bradbury, Charlotte A, McVerry, Bryan J, Lawler, Patrick R, Berger, Jeffrey S, Gong, Michelle N, Carrier, Marc, Reynolds, Harmony R, Kumar, Anand, Turgeon, Alexis F, Kornblith, Lucy Z, Kahn, Susan R, Marshall, John C, Kim, Keri S, Houston, Brett L, Derde, Lennie PG, Cushman, Mary, Tritschler, Tobias, Angus, Derek C, Godoy, Lucas C, McQuilten, Zoe, Kirwan, Bridget-Anne, Farkouh, Michael E, Brooks, Maria M, Lewis, Roger J, Berry, Lindsay R, Lorenzi, Elizabeth, Gordon, Anthony C, Ahuja, Tania, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Contreras, Aira, Costantini, Todd W, de Brouwer, Sophie, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Eng, Heather F, Escobedo, Jorge, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Froess, Joshua D, Fu, Zhuxuan, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, Girard, Timothy D, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Haniffa, Rashan, Hegde, Sheila M, Hendrickson, Carolyn M, Higgins, Alisa M, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Huang, David T, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Kutcher, Matthew E, Laffan, Michael A, Lamontagne, Francois, Le Gal, Grégoire

المصدر: New England Journal of Medicine. 385(9)

مصطلحات موضوعية: Clinical Trials and Supportive Activities, Clinical Research, Comparative Effectiveness Research, Cardiovascular, Good Health and Well Being, Aged, Anticoagulants, COVID-19, Critical Illness, Female, Hemorrhage, Heparin, Hospital Mortality, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Respiration, Artificial, Thrombosis, Treatment Failure, COVID-19 Drug Treatment, REMAP-CAP Investigators, ACTIV-4a Investigators, ATTACC Investigators, Medical and Health Sciences, General & Internal Medicine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0w99982h

المؤلفون: Lawler, Patrick R, Goligher, Ewan C, Berger, Jeffrey S, Neal, Matthew D, McVerry, Bryan J, Nicolau, Jose C, Gong, Michelle N, Carrier, Marc, Rosenson, Robert S, Reynolds, Harmony R, Turgeon, Alexis F, Escobedo, Jorge, Huang, David T, Bradbury, Charlotte A, Houston, Brett L, Kornblith, Lucy Z, Kumar, Anand, Kahn, Susan R, Cushman, Mary, McQuilten, Zoe, Slutsky, Arthur S, Kim, Keri S, Gordon, Anthony C, Kirwan, Bridget-Anne, Brooks, Maria M, Higgins, Alisa M, Lewis, Roger J, Lorenzi, Elizabeth, Berry, Scott M, Berry, Lindsay R, Aday, Aaron W, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Costantini, Todd W, de Brouwer, Sophie, Derde, Lennie PG, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, García-Madrona, Sebastian, Girard, Timothy D, Godoy, Lucas C, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Hamburg, Naomi M, Haniffa, Rashan, Hanna, George, Hanna, Nicholas, Hegde, Sheila M, Hendrickson, Carolyn M, Hite, R Duncan, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Iyer, Vivek N, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei L, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Krishnan, Vidya

المصدر: New England Journal of Medicine. 385(9)

مصطلحات موضوعية: Cardiovascular, Clinical Trials and Supportive Activities, Clinical Research, Hematology, Transplantation, Good Health and Well Being, Adult, Aged, Anticoagulants, COVID-19, Female, Hemorrhage, Heparin, Heparin, Low-Molecular-Weight, Hospital Mortality, Humans, Male, Middle Aged, Survival Analysis, Thrombosis, COVID-19 Drug Treatment, ATTACC Investigators, ACTIV-4a Investigators, REMAP-CAP Investigators, Medical and Health Sciences, General & Internal Medicine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/52q469xv

المؤلفون: REMAP-CAP Investigators, ACTIV-4a Investigators, ATTACC Investigators, Goligher, Ewan C, Bradbury, Charlotte A, McVerry, Bryan J, Lawler, Patrick R, Berger, Jeffrey S, Gong, Michelle N, Carrier, Marc, Reynolds, Harmony R, Kumar, Anand, Turgeon, Alexis F, Kornblith, Lucy Z, Kahn, Susan R, Marshall, John C, Kim, Keri S, Houston, Brett L, Derde, Lennie PG, Cushman, Mary, Tritschler, Tobias, Angus, Derek C, Godoy, Lucas C, McQuilten, Zoe, Kirwan, Bridget-Anne, Farkouh, Michael E, Brooks, Maria M, Lewis, Roger J, Berry, Lindsay R, Lorenzi, Elizabeth, Gordon, Anthony C, Ahuja, Tania, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Contreras, Aira, Costantini, Todd W, de Brouwer, Sophie, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Eng, Heather F, Escobedo, Jorge, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Froess, Joshua D, Fu, Zhuxuan, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, Girard, Timothy D, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Haniffa, Rashan, Hegde, Sheila M, Hendrickson, Carolyn M, Higgins, Alisa M, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Huang, David T, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Kutcher, Matthew E

المصدر: The New England journal of medicine. 385(9)

مصطلحات موضوعية: REMAP-CAP Investigators, ACTIV-4a Investigators, ATTACC Investigators, Humans, Thrombosis, Critical Illness, Hemorrhage, Heparin, Anticoagulants, Treatment Failure, Respiration, Artificial, Hospital Mortality, Logistic Models, Odds Ratio, Aged, Middle Aged, Female, Male, COVID-19, Clinical Research, Cardiovascular, Clinical Trials and Supportive Activities, Comparative Effectiveness Research, General & Internal Medicine, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0w99982h

المؤلفون: ATTACC Investigators, ACTIV-4a Investigators, REMAP-CAP Investigators, Lawler, Patrick R, Goligher, Ewan C, Berger, Jeffrey S, Neal, Matthew D, McVerry, Bryan J, Nicolau, Jose C, Gong, Michelle N, Carrier, Marc, Rosenson, Robert S, Reynolds, Harmony R, Turgeon, Alexis F, Escobedo, Jorge, Huang, David T, Bradbury, Charlotte A, Houston, Brett L, Kornblith, Lucy Z, Kumar, Anand, Kahn, Susan R, Cushman, Mary, McQuilten, Zoe, Slutsky, Arthur S, Kim, Keri S, Gordon, Anthony C, Kirwan, Bridget-Anne, Brooks, Maria M, Higgins, Alisa M, Lewis, Roger J, Lorenzi, Elizabeth, Berry, Scott M, Berry, Lindsay R, Aday, Aaron W, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Costantini, Todd W, de Brouwer, Sophie, Derde, Lennie PG, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, García-Madrona, Sebastian, Girard, Timothy D, Godoy, Lucas C, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Hamburg, Naomi M, Haniffa, Rashan, Hanna, George, Hanna, Nicholas, Hegde, Sheila M, Hendrickson, Carolyn M, Hite, R Duncan, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Iyer, Vivek N, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei L, King, Andrew J

المصدر: The New England journal of medicine. 385(9)

مصطلحات موضوعية: ATTACC Investigators, ACTIV-4a Investigators, REMAP-CAP Investigators, Humans, Thrombosis, Hemorrhage, Heparin, Heparin, Low-Molecular-Weight, Anticoagulants, Hospital Mortality, Survival Analysis, Adult, Aged, Middle Aged, Female, Male, COVID-19, Hematology, Clinical Trials and Supportive Activities, Transplantation, Clinical Research, Cardiovascular, General & Internal Medicine, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/52q469xv

المؤلفون: Meurer, William, Schmitzberger, Florian, Yeatts, Sharon, Ramakrishnan, Viswanathan, Abella, Benjamin, Aufderheide, Tom, Barsan, William, Benoit, Justin, Berry, Scott, Black, Joy, Bozeman, Nia, Broglio, Kristine, Brown, Jeremy, Brown, Kimberly, Carlozzi, Noelle, Caveney, Angela, Cho, Sung-Min, Chung-Esaki, Hangyul, Clevenger, Robert, Conwit, Robin, Cooper, Richelle, Crudo, Valentina, Daya, Mohamud, Harney, Deneil, Hsu, Cindy, Johnson, Nicholas J., Khan, Imad, Khosla, Shaveta, Kline, Peyton, Kratz, Anna, Kudenchuk, Peter, Lewis, Roger J., Madiyal, Chaitra, Meyer, Sara, Mosier, Jarrod, Mouammar, Marwan, Neth, Matthew, O'Neil, Brian, Paxton, James, Perez, Sofia, Perman, Sarah, Sozener, Cemal, Speers, Mickie, Spiteri, Aimee, Stevenson, Valerie, Sunthankar, Kavita, Tonna, Joseph, Youngquist, Scott, Geocadin, Romergryko, Silbergleit, Robert

المساهمون: Neurology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Bayesian adaptive trial, Cardiopulmonary resuscitation, Hypothermia, Induced, Neuroprotection, Out-of-hospital cardiac arrest

وصف الملف: application/pdf

Relation: Meurer W, Schmitzberger F, Yeatts S, et al. Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest. Preprint. Res Sq. 2024;rs.3.rs-4033108. Published 2024 Jun 21. doi:10.21203/rs.3.rs-4033108/v1; https://hdl.handle.net/1805/42983

الاتاحة: https://hdl.handle.net/1805/42983

المؤلفون: Anpalagan, Keerthi, Dotel, Ravindra, MacFadden, Derek R, Smith, Simon, Voss, Lesley, Petersiel, Neta, Marks, Michael, Marsh, Julie, Mahar, Robert K, McGlothlin, Anna, Lee, Todd C, Goodman, Anna, Morpeth, Susan, Davis, Joshua S, Tong, Steven Y C, Bowen, Asha C, Bonten, Marc, Daneman, Nick, van Hal, Sebastiaan J, Heriot, George S, Lewis, Roger J, Lye, David C, McQuilten, Zoe, Paterson, David L, Robinson, J Owen, Roberts, Jason A, Scarborough, Matthew, Webb, Steve A, Whiteway, Lynda, Walls, Genevieve, Yahav, Dafna, Hensgens, Marjolein, Cheng, Matthew P

المساهمون: Australian National Health and Medical Research Council, Canadian Institutes of Health Research, Health Research Council of New Zealand, National Institute for Health and Care Research, Medical Research Council, Singapore National Medical Research Council, National Institutes of Health, Netherlands Organisation for Health Research and Development, Starship Foundation

المصدر: Clinical Infectious Diseases ; ISSN 1058-4838 1537-6591

الاتاحة: http://dx.doi.org/10.1093/cid/ciae289
https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciae289/58530166/ciae289.pdf

المؤلفون: Angus, Derek C, Berry, Scott, Lewis, Roger J, Al-Beidh, Farah, Arabi, Yaseen, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bonten, Marc, Broglio, Kristine, Brunkhorst, Frank, Cheng, Allen C, Chiche, Jean-Daniel, De Jong, Menno, Detry, Michelle, Goossens, Herman, Gordon, Anthony, Green, Cameron, Higgins, Alisa M, Hullegie, Sebastiaan J, Kruger, Peter, Lamontagne, Francois, Litton, Edward, Marshall, John, McGlothlin, Anna, McGuinness, Shay, Mouncey, Paul, Murthy, Srinivas, Nichol, Alistair, O'Neill, Genevieve K, Parke, Rachael, Parker, Jane, Rohde, Gernot, Rowan, Kathryn, Turner, Anne, Young, Paul, Derde, Lennie, McArthur, Colin, Webb, Steven A

المصدر: Annals of the American Thoracic Society. (ja)

مصطلحات موضوعية: Influenza, Cancer, Clinical Research, Lung, Clinical Trials and Supportive Activities, Vaccine Related, Pneumonia & Influenza, Comparative Effectiveness Research, Patient Safety, Infectious Diseases, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Anti-Bacterial Agents, Antiviral Agents, Betacoronavirus, COVID-19, Community-Acquired Infections, Coronavirus Infections, Evidence-Based Medicine, Humans, Influenza, Human, Pandemics, Pneumonia, Pneumonia, Viral, Point-of-Care Systems, SARS-CoV-2, randomized clinical trial, Bayesian adaptive platform trial, master protocol, community-acquired pneumonia, coronavirus disease 2019, Bayesian adaptive, platform trial

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8mr5q2r5

المؤلفون: Angus, Derek C, Berry, Scott, Lewis, Roger J, Al-Beidh, Farah, Arabi, Yaseen, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bonten, Marc, Broglio, Kristine, Brunkhorst, Frank, Cheng, Allen C, Chiche, Jean-Daniel, De Jong, Menno, Detry, Michelle, Goossens, Herman, Gordon, Anthony, Green, Cameron, Higgins, Alisa M, Hullegie, Sebastiaan J, Kruger, Peter, Lamontagne, Francois, Litton, Edward, Marshall, John, McGlothlin, Anna, McGuinness, Shay, Mouncey, Paul, Murthy, Srinivas, Nichol, Alistair, O'Neill, Genevieve K, Parke, Rachael, Parker, Jane, Rohde, Gernot, Rowan, Kathryn, Turner, Anne, Young, Paul, Derde, Lennie, McArthur, Colin, Webb, Steven A

المصدر: Annals of the American Thoracic Society. 17(7)

مصطلحات موضوعية: Humans, Community-Acquired Infections, Pneumonia, Viral, Coronavirus Infections, Pneumonia, Anti-Bacterial Agents, Antiviral Agents, Evidence-Based Medicine, Point-of-Care Systems, Influenza, Human, Pandemics, Betacoronavirus, COVID-19, SARS-CoV-2, Bayesian adaptive, community-acquired pneumonia, coronavirus disease 2019, master protocol, platform trial, randomized clinical trial, Bayesian adaptive platform trial, Respiratory System, Clinical Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8mr5q2r5

المؤلفون: Tolles, Juliana, Waterman, Gabriel, Coffey, Charles E, Sandoval, Rebecca, Fleischman, Ross J, Hess, Mailee, Sarff, Laura, Lewis, Roger J, Spellberg, Brad, BRAVE Study Group

المصدر: PloS one. 15(1)

مصطلحات موضوعية: BRAVE Study Group, Humans, Bed Rest, Length of Stay, Prospective Studies, Program Evaluation, Behavior Therapy, Adult, Aged, Middle Aged, Intensive Care Units, Female, Male, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0qg5w02g

المؤلفون: Lorenzi, Elizabeth, Crawford, Amy M., Anderson, Craig S., Menon, Bijoy, Chen, Xiaoying, Mistry, Eva, Khatri, Pooja, Elm, Jordan J., Beall, Jonathan, Saville, Benjamin R., Berry, Scott M., Lewis, Roger J.

المصدر: Stroke (00392499); Jan2025, Vol. 56 Issue 1, p198-208, 11p

المؤلفون: Pedigo, Ryan, Tolles, Juliana, Watcha, Daena, Kaji, Amy H., Lewis, Roger J., Stark, Elena, Jordan, Jaime

المصدر: Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health. 21(1)

مصطلحات موضوعية: Education, Intubation

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0wn696m8

المؤلفون: Higgins, Alisa M., Berry, Lindsay R., Lorenzi, Elizabeth, Murthy, Srinivas, Mcquilten, Zoe K., Mouncey, Paul R., Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M., Beane, Abigail, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bonten, Marc J.M., Bradbury, Charlotte A., Brunkhorst, Frank Martin, Burrell, Aidan, Buzgau, Adrian, Buxton, Meredith Becker, Charles, Walton N., Cove, Matthew E., Detry, Michelle A., Estcourt, Lise J., Fagbodun, Elizabeth O., Fitzgerald, Mark, Girard, Timothy D., Goligher, Ewan C., Goossens, Herman, Haniffa, Rashan, Hills, Thomas, Horvat, Christopher M., Huang, David T., Ichihara, Nao, Lamontagne, Francois, Marshall, John C., Mcauley, Daniel F., Mcglothlin, Anna E., Mcguinness, Shay P., Mcverry, Bryan J., Neal, Matthew D., Nichol, Alistair D., Parke, Rachael L., Parker, Jane C., Parry-Billings, Karen, Peters, Sam E.C., Reyes, Luis Felipe, Rowan, Kathryn M., Saito, Hiroki, Santos, Marlene S., Saunders, Christina T., Serpa-Neto, Ary, Seymour, Christopher W., Shankar-Hari, Manu, Stronach, Lucy M., Turgeon, Alexis F., Turner, Anne M., van de Veerdonk, Frank Leo, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J., Angus, Derek C., Mcarthur, Colin J., Berry, Scott, Derde, Lennie, Gordon, Anthony C., Webb, Steve A.R., Lawler, Patrick

المساهمون: Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Raymond Poincaré (Garches) GHU AP-HP Université Paris-Saclay, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), 2002132, 447335, 602525, 215522, Pittsburgh Foundation, PF, Amgen, Health Research Board, HRB: CTN 2014-012, Horizon 2020 Framework Programme, H2020: 101003589, Translational Breast Cancer Research Consortium, TBCRC, Canadian Institutes of Health Research, IRSC: 158584, Heart and Stroke Foundation of Canada, HSF, National Institute for Health and Care Research, NIHR, European Commission, EC, National Health and Medical Research Council, NHMRC: 1101719, APP194811, CS-2016-16-011, GNT2008447, RP-2015-06-18, Office of Health and Medical Research, OHMR, Health Research Council of New Zealand, HRC: 16/631, Eisai, Ministère des Affaires Sociales et de la Santé: PHRC-20-0147, Université Pierre et Marie Curie, UPMC, NIHR Imperial Biomedical Research Centre, BRC, Minderoo Foundation, Funding/Support : The Platform for European Preparedness Against (Re-) emerging Epidemics (PREPARE) consortium by the European Union, FP7-HEALTH-2013-INNOVATION-1 (#602525), the Rapid European COVID-19 Emergency Research response (RECOVER) consortium by the European Union’s Horizon 2020 research and innovation programme (#101003589), the Australian National Health and Medical Research Council (#APP1101719), the Australian Medical Research Future Fund (#APP2002132), the Health Research Council of New Zealand (#16/631), the Canadian Institutes of Health Research Strategy for Patient-Oriented Research Innovative Clinical Trials Program Grant (#158584) and the Canadian Institute of Health Research COVID-19 Rapid Research Funding (#447335), the UK National Institute for Health Research (NIHR) and the NIHR Imperial Biomedical Research Centre, the Health Research Board of Ireland (CTN 2014-012), the UPMC Learning While Doing Program, the Translational Breast Cancer Research Consortium, the French Ministry of Health (PHRC-20-0147), the Wellcome Trust Innovations Project (215522), the Minderoo Foundation, the EU Programme Emergency Support Instrument, the NHS Blood and Transplant Research and Development Programme, the Translational Breast Cancer Research Consortium, the NSW Office of Health and Medical Research, Amgen, Eisai, and the Pittsburgh Foundation. Dr Higgins is funded by an NHMRC Emerging Leadership Fellowship (GNT2008447). Dr McQuilten is funded by an NHMRC Emerging Leadership Fellowship (APP194811). Dr Gordon is funded by an NIHR Research Professorship (RP-2015-06-18) and Dr Shankar-Hari by an NIHR Clinician Scientist Fellowship (CS-2016-16-011). Dr Turgeon is the Chairholder of the Canada Research Chair in Critical Care Neurology and Trauma. Dr Lawler is supported by a career award from the Heart and Stroke Foundation of Canada., European Project: 602525,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,PREPARE(2014)

المصدر: ISSN: 0098-7484.

مصطلحات موضوعية: Adaptive platform trial randomized controlled trial intensive care, pneumonia COVID-19 antiplatelet immunoglobulin antiviral corticosteroid immune modulation anticoagulation, Adaptive platform trial, randomized controlled trial, intensive care, pneumonia, COVID-19, antiplatelet, immunoglobulin, antiviral, corticosteroid, immune modulation, anticoagulation, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/36525245; info:eu-repo/grantAgreement/EC/FP7/602525/EU/Platform foR European Preparedness Against (Re-)emerging Epidemics/PREPARE; hal-03949589; https://hal.science/hal-03949589; https://hal.science/hal-03949589/document; https://hal.science/hal-03949589/file/dan_combine_final-MMA.pdf; PUBMED: 36525245

الاتاحة: https://hal.science/hal-03949589
https://hal.science/hal-03949589/document
https://hal.science/hal-03949589/file/dan_combine_final-MMA.pdf
https://doi.org/10.1001/jama.2022.23257

المؤلفون: REMAP-CAP Investigators, Hills, Thomas E, Lorenzi, Elizabeth, Berry, Lindsay R, Shyamsundar, Murali, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen, Aryal, Diptesh, Au, Carly, Beane, Abigail, Bhimani, Zahra, Bonten, Marc, Bradbury, Charlotte A, Brunkhorst, Frank M, Burrell, Aidan, Buxton, Meredith, Calfee, Carolyn S, Cecconi, Maurizio, Cheng, Allen C, Cove, Matthew E, Detry, Michelle A, Estcourt, Lise J, Fitzgerald, Mark, Goligher, Ewan C, Goossens, Herman, Green, Cameron, Haniffa, Rashan, Harrison, David A, Hashmi, Madiha, Higgins, Alisa M, Horvat, Christopher, Huang, David T, Ichihara, Nao, Jayakumar, Deva, Kruger, Peter S, Lamontagne, François, Lampro, Lamprini, Lawler, Patrick R, Marshall, John C, Mason, Alexina J, McGlothlin, Anna, McGuinness, Shay, McQuilten, Zoe K, McVerry, Bryan J, Mouncey, Paul R, Murthy, Srinivas, Neal, Matthew D, Nichol, Alistair D, O'Kane, Cecilia M, Parke, Rachael L, Parker, Jane C, Rabindrarajan, Ebenezer, Reyes, Luis F, Rowan, Kathryn M, Saito, Hiroki, Santos, Marlene, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Sinha, Pratik, Thompson, B Taylor, Turgeon, Alexis F, Turner, Anne M, van de Veerdonk, Frank, Weis, Sebastian, Young, Ian S, Zarychanski, Ryan, Lewis, Roger J, McArthur, Colin J, Angus, Derek C, Berry, Scott M, Derde, Lennie PG, Webb, Steve A, Gordon, Anthony C, McAuley, Daniel F

مصطلحات موضوعية: Humans, Bayes Theorem, COVID-19, COVID-19 Drug Treatment, Critical Illness, Hospital Mortality, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Simvastatin, Treatment Outcome

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/363268; https://doi.org/10.17863/CAM.105415

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/363268
https://doi.org/10.17863/CAM.105415

المؤلفون: Mahar, Robert K, McGlothlin, Anna, Dymock, Michael, Lee, Todd C, Lewis, Roger J, Lumley, Thomas, Mora, Jocelyn, Price, David J, Saville, Benjamin R, Snelling, Tom, Turner, Rebecca, Webb, Steven A, Davis, Joshua S, Tong, Steven YC, Marsh, Julie A, Bowen, Asha, Cheng, Matthew, Daneman, Nick, Davis, Joshua, Goodman, Anna, Heriot, George, Lewis, Roger, Lye, David, Marsh, Julie, McQuilten, Zoe, Morpeth, Susan, Paterson, David, Price, David, Roberts, Jason, Robinson, Owen, Scarborough, Matthew, Tong, Steven, van Hal, Sebastiaan, Walls, Genevieve, Webb, Steve, Whiteway, Lynda, Yahav, Dafna

المصدر: Trials , 24 , Article 795. (2023)

مصطلحات موضوعية: Bayesian, Platform, Staphylococcus aureus, Trial, Randomised, This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Adaptive

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10183766/1/Mahar-2023-Trials.pdf; https://discovery.ucl.ac.uk/id/eprint/10183766/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10183766/1/Mahar-2023-Trials.pdf
https://discovery.ucl.ac.uk/id/eprint/10183766/

المؤلفون: Lawler, Patrick R., Derde, Lennie P.G., Van De Veerdonk, Frank L., McVerry, Bryan J., Huang, David T., Berry, Lindsay R., Lorenzi, Elizabeth, Van Kimmenade, Roland, Gommans, Frank, Vaduganathan, Muthiah, Leaf, David E., Baron, Rebecca M., Kim, Edy Y., Frankfurter, Claudia, Epelmaņ, Slava, Kwan, Yvonne, Grieve, Richard, O'Neill, Stephen, Sadique, Zia, Puskarich, Michael, Marshall, John C., Higgins, Alisa M., Mouncey, Paul R., Rowan, Kathryn M., Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M., Au, Carly, Beane, Abi, Van Bentum-Puijk, Wilma, Bonten, Marc J.M., Bradbury, Charlotte A., Brunkhorst, Frank M., Burrell, Aidan, Buzgau, Adrian, Buxton, Meredith, Cecconi, Maurizio, Cheng, Allen C., Cove, Matthew, Detry, Michelle A., Estcourt, Lise J., Ezekowitz, Justin, Fitzgerald, Mark, Gattas, David, Godoy, Lucas C., Goossens, Herman, Haniffa, Rashan, Harrison, David A., Hills, Thomas, Horvat, Christopher M., Ichihara, Nao, Lamontagne, Francois, Linstrum, Kelsey M., McAuley, Daniel F., McGlothlin, Anna, McGuinness, Shay P., McQuilten, Zoe, Murthy, Srinivas, Nichol, Alistair D., Owen, David R.J., Parke, Rachael L., Parker, Jane C., Pollock, Katrina M., Reyes, Luis Felipe, Saito, Hiroki, Santos, Marlene S., Saunders, Christina T., Seymour, Christopher W., Shankar-Hari, Manu, Singh, Vanessa, Turgeon, Alexis F., Turner, Anne M., Zarychanski, Ryan, Green, Cameron, Lewis, Roger J., Angus, Derek C., Berry, Scott, Gordon, Anthony C., McArthur, Colin J., Webb, Steve A.

المصدر: Lawler , P R , Derde , L P G , Van De Veerdonk , F L , McVerry , B J , Huang , D T , Berry , L R , Lorenzi , E , Van Kimmenade , R , Gommans , F , Vaduganathan , M , Leaf , D E , Baron , R M , Kim , E Y , Frankfurter , C , Epelmaņ , S , Kwan , Y , Grieve , R , O'Neill , S , Sadique , Z , Puskarich , M , Marshall , J C , Higgins ....

مصطلحات موضوعية: Female, Humans, Male, Middle Aged, Angiotensin Receptor Antagonists/pharmacology, Angiotensin-Converting Enzyme Inhibitors/pharmacology, Bayes Theorem, COVID-19/therapy, Renin-Angiotensin System/drug effects, Hospitalization, COVID-19 Drug Treatment/methods, Critical Illness, Receptors, Chemokine/antagonists & inhibitors, /dk/atira/pure/subjectarea/asjc/2700/2700, name=General Medicine

وصف الملف: application/pdf

الاتاحة: https://pure.qub.ac.uk/en/publications/8cae3556-8039-49ea-a414-6da1b5a01052
https://doi.org/10.1001/jama.2023.4480
https://pureadmin.qub.ac.uk/ws/files/445375124/REMAP_CAP_ACE2_RAS_Domain_COVID_19_ACCEPTED_3_9_2023.pdf

المؤلفون: Mahar, Robert K., McGlothlin, Anna, Dymock, Michael, Lee, Todd C., Lewis, Roger J., Lumley, Thomas, Mora, Jocelyn, Price, David J., Saville, Benjamin R., Snelling, Tom, Turner, Rebecca, Webb, Steven A., Davis, Joshua S., Tong, Steven Y. C., Marsh, Julie A., Bowen, Asha, Cheng, Matthew, Daneman, Nick, Davis, Joshua, Goodman, Anna, Heriot, George, Lewis, Roger, Lye, David, Marsh, Julie, McQuilten, Zoe, Morpeth, Susan, Paterson, David, Price, David, Roberts, Jason, Robinson, Owen, Scarborough, Matthew, Tong, Steven, van Hal, Sebastiaan, Walls, Genevieve, Webb, Steve, Whiteway, Lynda, Yahav, Dafna

المساهمون: National Health and Medical Research Council, Canadian Institutes of Health Research, Health Research Council of New Zealand, Athlae Lyon/Starship Foundation Trust, National Medical Research Council, United Kingdom National Institute for Health Research, Medical Research Council

المصدر: Trials ; volume 24, issue 1 ; ISSN 1745-6215

الاتاحة: http://dx.doi.org/10.1186/s13063-023-07718-x
https://link.springer.com/content/pdf/10.1186/s13063-023-07718-x.pdf
https://link.springer.com/article/10.1186/s13063-023-07718-x/fulltext.html

المؤلفون: Nordness, Mina F., Maiga, Amelia W., Wilson, Laura D., Koyama, Tatsuki, Rivera, Erika L., Rakhit, Shayan, de Riesthal, Michael, Motuzas, Cari L., Cook, Madison R., Gupta, Deepak K., Jackson, James C., Williams Roberson, Shawniqua, Meurer, William J., Lewis, Roger J., Manley, Geoffrey T., Pandharipande, Pratik P., Patel, Mayur B.

المساهمون: National Institute on Aging, National Institute of General Medical Sciences, School of Medicine, Vanderbilt University, National Institute of Neurological Disorders and Stroke, National Heart, Lung, and Blood Institute, U.S. Department of Veterans Affairs, Eastern Association for the Surgery of Trauma, Vanderbilt Institute for Clinical and Translational Research

المصدر: Critical Care ; volume 27, issue 1 ; ISSN 1364-8535

الاتاحة: http://dx.doi.org/10.1186/s13054-023-04479-6
https://link.springer.com/content/pdf/10.1186/s13054-023-04479-6.pdf
https://link.springer.com/article/10.1186/s13054-023-04479-6/fulltext.html

المؤلفون: de Kretser, Dana, Mora, Jocelyn, Bloomfield, Max, Campbell, Anita, Cheng, Matthew P, Guy, Stephen, Hensgens, Marjolein, Kalimuddin, Shirin, Lee, Todd C, Legg, Amy, Mahar, Robert K, Marks, Michael, Marsh, Julie, McGlothin, Anna, Morpeth, Susan C, Sud, Archana, Ten Oever, Jaap, Yahav, Dafna, Bonten, Marc, Bowen, Asha C, Daneman, Nick, van Hal, Sebastiaan J, Heriot, George S, Lewis, Roger J, Lye, David C, McQuilten, Zoe, Paterson, David L, Owen Robinson, J, Roberts, Jason A, Scarborough, Matthew, Webb, Steve A, Whiteway, Lynda, Tong, Steven Y C, Davis, Joshua S, Walls, Genevieve, Goodman, Anna L, Marsh, J, Tong, S Y C, Davis, J S, Goodman, A L, Walls, G, Morpeth, S C, Hensgens, M, Mora, J, Yahav, D, McGlothlin, A, Cheng, M P, Anagnostou, Nick, Acrhuleta, Sophia, Athan, Eugene

المساهمون: Australian National Health and Medical Research Council, Canadian Institutes of Health Research, New Zealand Health Research Council, United Kingdom National Institute for Health and Care Research, Medical Research Council, Singapore National Medical Research Council, Starship Foundation, Advancing Queensland Clinical Fellowship, National Health and Medical Research Council, Counties Manukau Tupu Health Fund, Te Niwha Infectious Diseases Research Fund

المصدر: Clinical Infectious Diseases ; volume 79, issue 4, page 871-887 ; ISSN 1058-4838 1537-6591

الاتاحة: https://doi.org/10.1093/cid/ciad666
https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciad666/59084875/ciad666.pdf
https://academic.oup.com/cid/article-pdf/79/4/871/59764956/ciad666.pdf