المؤلفون: Yuan Liu, Congqing Hao, Wei Zhang, Yuzhou Liu, Sen Guo, Ran Li, Meng Peng, Yawei Xu, Xiaoxin Pei, Haibo Yang, Yintao Zhao

المصدر: Journal of Advanced Research, Vol 37, Iss , Pp 107-117 (2022)

مصطلحات موضوعية: Leucine-rich repeat kinase-2, Cardiac remodelling, Autophagy, Bcl-2, Beclin1, Rab7, Medicine (General), R5-920, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2090123221001387; https://doaj.org/toc/2090-1232

URL الوصول: https://doaj.org/article/81a13a0e3f524fdc8716809d3a9d84c4

المؤلفون: Christian U. von Linstow, Ziv Gan-Or, Patrik Brundin

المصدر: Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Parkinson’s disease, Precision medicine, Personalized medicine, Glucocerebrosidase, GCase, Leucine-rich repeat kinase-2, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40035-020-00218-x; https://doaj.org/toc/2047-9158

URL الوصول: https://doaj.org/article/34c321cb5418441d84eaca92575bfb98

المؤلفون: Sylvie Delcambre, Jenny Ghelfi, Nassima Ouzren, Léa Grandmougin, Catherine Delbrouck, Philip Seibler, Kobi Wasner, Jan O. Aasly, Christine Klein, Joanne Trinh, Sandro L. Pereira, Anne Grünewald

المصدر: Frontiers in Neurology, Vol 11 (2020)

مصطلحات موضوعية: leucine-rich repeat kinase-2 (LRRK2), G2019S, Parkinson's disease, penetrance, mitochondria, mitochondrial DNA (mtDNA), Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fneur.2020.00881/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/1ebd40586a1b4db891732da8ccc4aff2

المؤلفون: Shuibing Chen, Brandoch D. Cook, Todd Evans, Qisheng Zhang, Nicholas R Walker

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, DMSO, dimethyl sulfoxide, ERK, extracellular signal–regulated kinase, Biochemistry, Bone remodeling, Myoblasts, CETSA, cellular thermal shift assay, Mice, GSK-3, Osteogenesis, S396, serine-396, CDK, cyclin-dependent kinase, Tm, melting temperature, biology, Chemistry, Kinase, Osteoblast, Cell Differentiation, AZD, AstraZeneca GSK3-β-specific inhibitor AZD2858, CHK, checkpoint kinase, Alzheimer's disease, Cell biology, inhibitor, medicine.anatomical_structure, GSK3-β, glycogen synthase kinase 3-beta, osteoblast, signaling, C2C12, LRRK2, leucine-rich repeat kinase-2, Research Article, Signal Transduction, small molecule, Bone morphogenetic protein, AD, Alzheimer’s disease, Cell Line, 03 medical and health sciences, Cyclin-dependent kinase, medicine, Animals, Humans, Molecular Biology, GSK3B, hSkMSCs, human skeletal muscle satellite cells, Glycogen Synthase Kinase 3 beta, 030102 biochemistry & molecular biology, ALP, alkaline phosphatase, Dose-Response Relationship, Drug, pNPP, p-nitrophenylphosphate, BMP, bone morphogenetic protein, Cell Biology, glycogen synthase kinase 3, 030104 developmental biology, biology.protein, CHIR, Wnt signaling activator CHIR99021, MAPK, mitogen-activated protein kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59af398862be85f30c8b96a386f7581
http://europepmc.org/articles/PMC8138761

المؤلفون: Sylvie Delcambre, Jenny Ghelfi, Nassima Ouzren, Léa Grandmougin, Catherine Delbrouck, Philip Seibler, Kobi Wasner, Jan O. Aasly, Christine Klein, Joanne Trinh, Sandro L. Pereira, Anne Grünewald

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, leucine-rich repeat kinase-2 (LRRK2), G2019S, Parkinson's disease, penetrance, mitochondria, mitochondrial DNA (mtDNA), fibroblasts

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Mitochondrial_Mechanisms_of_LRRK2_G2019S_Penetrance_DOCX/12859556

الاتاحة: https://doi.org/10.3389/fneur.2020.00881.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Mitochondrial_Mechanisms_of_LRRK2_G2019S_Penetrance_DOCX/12859556

المؤلفون: Kazunari Kondo, Reiko Teshima, Saemi Obitsu

المصدر: Biological and Pharmaceutical Bulletin. 2011, 34(7):1078

المؤلفون: Fonds National de la Recherche - FnR [sponsor], Delcambre, Sylvie, Ghelfi, Jenny, Ouzren, Nassima, Grandmougin, Léa, Delbrouck, Catherine, Seibler, Philip, Wasner, Kobi, Aasly, Jan, Klein, Christine, Trinh, Joanne, Cardoso Pereira, Sandro Lino, Grünewald, Anne

مصطلحات الفهرس: leucine-rich repeat kinase-2 (LRRK2), G2019S, Parkinson’s disease, Penetrance, Mitochondria, mitochondrial DNA (mtDNA), fibroblasts, info:eu-repo/semantics/article

URL: http://orbilu.uni.lu/handle/10993/44428
http://orbilu.uni.lu/bitstream/10993/44428/2/Data_Sheet_1_Mitochondrial%20Mechanisms%20of%20LRRK2%20G2019S%20Penetrance.DOCX
http://orbilu.uni.lu/bitstream/10993/44428/1/Delcambre_et_al-2020-Frontiers_in_Neurology.pdf