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1Academic Journal
المؤلفون: Waring, Molly E, Hills, Mellanie T, Lessard, Darleen M, Saczynski, Jane S, Libby, Brooke A, Holovatska, Marta M, Kapoor, Alok, Kiefe, Catarina I, McManus, David D
المصدر: JMIR Cardio, Vol 3, Iss 2, p e15320 (2019)
مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Lessard, Darleen M, Tran, Vu Hoang, Parekh, Jay, Tisminetzky, Mayra S, Gore, Joel M, Yarzebski, Jorge, Granillo, Edgard, Nguyen, Tuyet T, Goldberg, Robert J.
المساهمون: Biostatistics and Health Services Research, Medicine, Population and Quantitative Health Sciences
المصدر: CJC open ; 6 ; 781 ; 789 ; United States
Relation: CJC Open; https://doi.org/10.1016/j.cjco.2024.02.001; http://hdl.handle.net/20.500.14038/53730
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3Academic Journal
المؤلفون: Ding, Eric Y., Han, Dong, Whitcomb, Cody, Bashar, Syed Khairul, Adaramola, Oluwaseun, Soni, Apurv, Saczynski, Jane, Fitzgibbons, Timothy P, Moonis, Majaz, Lubitz, Steven A., Lessard, Darleen M., Hills, Mellanie true, Barton, Bruce A., Chon, Ki, McManus, David D.
المساهمون: Graduate School of Biomedical Sciences, Department of Neurology, Division of Cardiovascular Medicine, Department of Medicine, Department of Population and Quantitative Health Sciences
المصدر: JMIR cardio ; 3 ; 1 ; e13850
مصطلحات موضوعية: atrial fibrillation, electrocardiography, mHealth, mobile health, photoplethysmography, screening, smartwatch, UMCCTS funding, Analytical, Diagnostic and Therapeutic Techniques and Equipment, Biomedical Engineering and Bioengineering, Biotechnology, Cardiology, Cardiovascular Diseases, Health Services Research, Telemedicine
Relation: Link to Article in PubMed; JMIR Cardio. 2019 May 15;3(1):e13850. doi:10.2196/13850. Link to article on publisher's site; 2561-1011 (Linking); http://hdl.handle.net/20.500.14038/46846; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2317&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1314; qhs_pp/1314
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4Academic Journal
المؤلفون: Wang, Weijia, Lessard, Darleen M., Saczynski, Jane, Goldberg, Robert J., Go, Alan S., Paul, Tenes J, Gracia, Ely, McManus, David D.
المساهمون: Department of Population and Quantitative Health Sciences, Department of Medicine, Division of Cardiovascular Medicine
المصدر: Journal of geriatric cardiology : JGC ; 17 ; 11 ; 653-658
مصطلحات موضوعية: Atrial fibrillation, Cognitive impairment, Frailty, Heart failure, Cardiology, Cardiovascular Diseases, Geriatrics
Relation: Link to Article in PubMed; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729184/; Wang WJ, Lessard D, Saczynski J, Goldberg RJ, Go AS, Paul T, Gracia E, McManus DD. Incident frailty and cognitive impairment by heart failure status in older patients with atrial fibrillation: the SAGE-AF study. J Geriatr Cardiol. 2020 Nov 28;17(11):653-658. doi:10.11909/j.issn.1671-5411.2020.11.007. PMID: 33343643; PMCID: PMC7729184. Link to article on publisher's site; 1671-5411 (Linking); http://hdl.handle.net/20.500.14038/41674; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5495&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/4465; oapubs/4465
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5Academic Journal
المؤلفون: Tran, Khanh-Van T., Majka, Jordan, Sanghai, Saket, Sardana, Mayank, Lessard, Darleen M., Milstone, Zachary J., Tanriverdi, Kahraman, Freedman, Jane E., Fitzgibbons, Timothy P, McManus, David D.
المساهمون: Graduate School of Biomedical Sciences, Department of Quantitative Health Sciences, Division of Cardiovascular Medicine, Department of Medicine
المصدر: Frontiers in cardiovascular medicine ; 6 ; 115
مصطلحات موضوعية: atrial fibrillation, cardiac remodeling, epicardial adipose tissue, inflammation, microRNA, Biological Factors, Cardiology, Cardiovascular Diseases, Nucleic Acids, Nucleotides, and Nucleosides, Pathological Conditions, Signs and Symptoms, Tissues
Relation: Link to Article in PubMed; Front Cardiovasc Med. 2019 Aug 14;6:115. doi:10.3389/fcvm.2019.00115. eCollection 2019. Link to article on publisher's site; 2297-055X (Linking); http://hdl.handle.net/20.500.14038/41156; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4961&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3945; oapubs/3945
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6Academic Journal
المؤلفون: Sanghai, Saket R., Sardana, Mayank, Hansra, Barinder, Lessard, Darleen M., Dahlberg, Seth T., Aurigemma, Gerard P., Fitzgibbons, Timothy P, McManus, David D.
المساهمون: Department of Quantitative Health Sciences, Division of Cardiovascular Medicine, Department of Medicine
المصدر: Frontiers in cardiovascular medicine ; 5 ; 76
مصطلحات موضوعية: atrial fibrillation, cardiac CT, catheter ablation, epicardial adipose tissue, left atrial remodeling, recurrence, Cardiology, Cardiovascular Diseases
Relation: Link to Article in PubMed; Front Cardiovasc Med. 2018 Jun 19;5:76. doi:10.3389/fcvm.2018.00076. eCollection 2018. Link to article on publisher's site; 2297-055X (Linking); http://hdl.handle.net/20.500.14038/40704; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4518&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3507; oapubs/3507
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7Academic Journal
المؤلفون: Wang, Weijia, Lessard, Darleen M., Abu, Hawa Ozien, McManus, David D., Mailhot, Tanya, Gurwitz, Jerry H., Goldberg, Robert J., Saczynski, Jane
المساهمون: Meyers Primary Care Institute, Department of Population and Quantitative Health Sciences, Division of Cardiovascular Medicine, Department of Medicine
المصدر: Journal of geriatric cardiology : JGC ; 17 ; 4 ; 177-183
مصطلحات موضوعية: Atrial fibrillation, Cognitive function, Hearing, Cardiology, Cardiovascular Diseases, Epidemiology, Geriatrics, Otorhinolaryngologic Diseases, Psychiatry and Psychology
Relation: Link to Article in PubMed; Wang WJ, Lessard D, Abu H, McManus DD, Mailhot T, Gurwitz JH, Goldberg RJ, Saczynski J. Hearing loss and cognitive decline among older adults with atrial fibrillation: the SAGE-AF study. J Geriatr Cardiol. 2020 Apr;17(4):177-183. doi:10.11909/j.issn.1671-5411.2020.04.002. PMID: 32362915; PMCID: PMC7189266. Link to article on publisher's site; 1671-5411 (Linking); http://hdl.handle.net/20.500.14038/46882; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2359&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1355; qhs_pp/1355
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8Academic Journal
المؤلفون: Nguyen, Hoa L, Yarzebski, Jorge L., Lessard, Darleen M., Gore, Joel M., McManus, David D., Goldberg, Robert J.
المساهمون: Medicine, Quantitative Health Sciences
المصدر: Journal of the American Heart Association ; 6
مصطلحات موضوعية: acute myocardial infarction, cardiogenic shock timing, hospital prognosis, population‐based study, Cardiology, Cardiovascular Diseases, Clinical Epidemiology, Epidemiology
Relation: Link to Article in PubMed; https://doi.org/10.1161/jaha.117.005566; Nguyen HL, Yarzebski J, Lessard D, Gore JM, McManus DD, Goldberg RJ. Ten-Year (2001-2011) Trends in the Incidence Rates and Short-Term Outcomes of Early Versus Late Onset Cardiogenic Shock After Hospitalization for Acute Myocardial Infarction. J Am Heart Assoc. 2017 Jun 7;6(6):e005566. doi:10.1161/JAHA.117.005566. PMID: 28592462; PMCID: PMC5669173.; 2047-9980 (Linking); http://hdl.handle.net/20.500.14038/40380; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4193&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3185; oapubs/3185
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9Academic Journal
المؤلفون: Bamgbade, Benita A., Sanghai, Saket, McManus, David D., Lessard, Darleen M., Waring, Molly E., Forrester, Sarah N, Pierre-Louis, Isabelle, Saczynski, Jane S.
المساهمون: Division of Cardiovascular Medicine, Department of Medicine
المصدر: Archives of gerontology and geriatrics ; 90 ; 104117
مصطلحات موضوعية: Cognitive impairment, Health-Related quality of life, Multimorbidity, Psychosocial, Symptom burden, Cardiology, Cardiovascular Diseases, Epidemiology, Geriatrics, Health Services Administration, Mental and Social Health, Psychiatry and Psychology, Psychological Phenomena and Processes, UMCCTS funding
Relation: Link to Article in PubMed; Bamgbade BA, Sanghai SR, McManus DD, Lessard D, Waring ME, Forrester S, Pierre-Louis I, Saczynski JS. Psychosocial and cognitive multimorbidity and health-related quality of life and symptom burden in older adults with atrial fibrillation: The systematic assessment of geriatric elements in atrial fibrillation (SAGE-AF) cohort study. Arch Gerontol Geriatr. 2020 May 28;90:104117. doi:10.1016/j.archger.2020.104117. Epub ahead of print. PMID: 32474170. Link to article on publisher's site; 0167-4943 (Linking); http://hdl.handle.net/20.500.14038/41454; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5252&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/4233; oapubs/4233
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10Academic Journal
المؤلفون: Coles, Andrew H., Tisminetzky, Mayra, Yarzebski, Jorge L., Lessard, Darleen M., Gore, Joel M., Darling, Chad E., Goldberg, Robert J.
المساهمون: Department of Emergency Medicine, Department of Medicine, Division of Cardiovascular Medicine, Department of Quantitative Health Sciences, Program in Gene Function and Expression
المصدر: Journal of the American Heart Association ; 4 ; 12
مصطلحات موضوعية: UMCCTS funding, Cardiology, Cardiovascular Diseases, Clinical Epidemiology, Epidemiology, Translational Medical Research
Relation: Link to Article in PubMed; J Am Heart Assoc. 2015 Dec 23;4(12). pii: e002303. doi:10.1161/JAHA.115.002303. Link to article on publisher's site; 2047-9980 (Linking); http://hdl.handle.net/20.500.14038/50492; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1063&context=umccts_pubs&unstamped=1; https://escholarship.umassmed.edu/umccts_pubs/63; 8310129; umccts_pubs/63
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11Academic Journal
المؤلفون: Mehawej, Jordy, Saczynski, Jane, Abu, Hawa Ozien, Gagnier, Marc, Bamgbade, Benita A., Lessard, Darleen M., Trymbulak, Katherine, Saleeba, Connor, Kiefe, Catarina I., Goldberg, Robert J., McManus, David D.
المساهمون: Department of Population and Quantitative Health Sciences, Department of Medicine, Division of Cardiovascular Medicine
المصدر: Canadian geriatrics journal : CGJ ; 24 ; 3 ; 174-183
مصطلحات موضوعية: anticoagulation, atrial fibrillation, patient engagement, shared decision-making, stroke, Cardiovascular Diseases, Epidemiology, Geriatrics, Health Services Administration, Health Services Research, Nervous System Diseases
Relation: Link to Article in PubMed; Mehawej J, Saczynski J, Abu HO, Gagnier M, Bamgbade BA, Lessard D, Trymbulak K, Saleeba C, Kiefe CI, Goldberg RJ, McManus DD. Factors Associated With Patient Engagement in Shared Decision-Making for Stroke Prevention Among Older Adults with Atrial Fibrillation. Can Geriatr J. 2021 Sep 1;24(3):174-183. doi:10.5770/cgj.24.475. PMID: 34484500; PMCID: PMC8390325. Link to article on publisher's site; 1925-8348 (Linking); http://hdl.handle.net/20.500.14038/46994; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2475&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1471; qhs_pp/1471
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12Academic Journal
المؤلفون: Chen, Jinying, Kiefe, Catarina I., Gagnier, Marc, Lessard, Darleen M., McManus, David D., Wang, Bo, Houston, Thomas K.
المساهمون: Department of Medicine, Division of Cardiovascular Medicine, Department of Population and Quantitative Health Sciences
المصدر: BMC cardiovascular disorders ; 21 ; 1 ; 383
مصطلحات موضوعية: Acute coronary syndrome, Cardiovascular disease, Care transition, Electronic health records, Natural language processing, Non-specific pain, Readmission, Cardiology, Cardiovascular Diseases, Epidemiology, Health Information Technology, Health Services Research, Pain Management, Pathological Conditions, Signs and Symptoms
Relation: Link to Article in PubMed; Chen J, Kiefe CI, Gagnier M, Lessard D, McManus D, Wang B, Houston TK. Non-specific pain and 30-day readmission in acute coronary syndromes: findings from the TRACE-CORE prospective cohort. BMC Cardiovasc Disord. 2021 Aug 9;21(1):383. doi:10.1186/s12872-021-02195-z. PMID: 34372783; PMCID: PMC8351351. Link to article on publisher's site; 1471-2261 (Linking); http://hdl.handle.net/20.500.14038/46935; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2419&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1415; qhs_pp/1415
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13Academic Journal
المؤلفون: McManus, David D., Kiefe, Catarina I., Lessard, Darleen M., Marino, Francesca, Goldberg, Robert J., Gurwitz, Jerry H., Wang, Weijia, Barton, Bruce A.
المساهمون: Division of Geriatric Medicine, Department of Medicine, Division of Cardiovascular Medicine, Department of Medicine, Department of Population and Quantitative Health Sciences
المصدر: Frontiers in cardiovascular medicine ; 6 ; 155
مصطلحات موضوعية: anticoagulation, atrial fibrillation, frailty, older adults, social isolation, Cardiology, Cardiovascular Diseases, Epidemiology, Geriatrics, Health Services Administration, Therapeutics
Relation: Link to Article in PubMed; Front Cardiovasc Med. 2019 Oct 30;6:155. doi:10.3389/fcvm.2019.00155. eCollection 2019. Link to article on publisher's site; 2297-055X (Linking); http://hdl.handle.net/20.500.14038/46854; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2327&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1324; qhs_pp/1324
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14Academic Journal
المؤلفون: Mercado-Lubo, Regino, Yarzebski, Jorge, Lessard, Darleen M., Gore, Joel M., Goldberg, Robert J.
المساهمون: Department of Medicine, Division of Cardiovascular Medicine, Department of Population and Quantitative Health Sciences
المصدر: The American journal of cardiology ; 125 ; 5 ; 673-677
مصطلحات موضوعية: Acute Myocardial Infarction, atrial fibrillation, heart failure, and ventricular fibrillation, acute hospitalization, Cardiology, Cardiovascular Diseases, Clinical Epidemiology, Epidemiology, Health Services Administration, Health Services Research
Relation: Link to Article in PubMed; Mercado-Lubo R, Yarzebski J, Lessard D, Gore J, Goldberg RJ. Changing Trends in the Landscape of Patients Hospitalized With Acute Myocardial Infarction (2001 to 2011) (from the Worcester Heart Attack Study). Am J Cardiol. 2020 Mar 1;125(5):673-677. doi:10.1016/j.amjcard.2019.12.009. Epub 2019 Dec 13. PMID: 31924320. Link to article on publisher's site; 0002-9149 (Linking); http://hdl.handle.net/20.500.14038/46858; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2332&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1329; qhs_pp/1329
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15Academic Journal
المؤلفون: Kundu, Amartya, Day, Kevin O., Lessard, Darleen M., Gore, Joel M., Yu, Hong, Akhter, Mohammed W., Fisher, Daniel Z., Hayward, Robert M. Jr, Henninger, Nils, Kapoor, Alok, Yarzebski, Jorge L., Goldberg, Robert J., McManus, David D.
المساهمون: Department of Neurology, Department of Quantitative Health Sciences, Department of Medicine, Division of Cardiovascular Medicine
المصدر: Journal of atrial fibrillation ; 10 ; 5 ; 1749
مصطلحات موضوعية: Anticoagulation, Atrial Fibrillation, Epidemiology, Outcomes, Cardiology, Cardiovascular Diseases, Clinical Epidemiology, Health Services Administration
Relation: Link to Article in PubMed; J Atr Fibrillation. 2018 Feb 28;10(5):1749. doi:10.4022/jafib.1749. eCollection 2018 Feb. Link to article on publisher's site; 1941-6911 (Linking); http://hdl.handle.net/20.500.14038/46752; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2213&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1212; qhs_pp/1212
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16Academic Journal
المؤلفون: Sardana, Mayank, Lessard, Darleen M., Barton, Bruce A., Mitchell, Gary F., Vaze, Aditya, McManus, David D.
المساهمون: Department of Quantitative Health Sciences, Department of Medicine, Division of Cardiovascular Medicine
المصدر: Journal of the American Heart Association ; 7 ; e008435
مصطلحات موضوعية: UMCCTS funding, atrial fibrillation, cardiovascular disease, echocardiography, epidemiology, left atrium, Cardiology, Cardiovascular Diseases
Relation: Link to Article in PubMed; J Am Heart Assoc. 2018 Mar 30;7(7). pii: e008435. doi:10.1161/JAHA.117.008435. Link to article on publisher's site; 2047-9980 (Linking); http://hdl.handle.net/20.500.14038/46719; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2177&context=qhs_pp&unstamped=1; https://escholarship.umassmed.edu/qhs_pp/1177; qhs_pp/1177
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17Academic Journal
المؤلفون: Vaze, Aditya, Tran, Khanh-Van T., Tanriverdi, Kahraman, Sardana, Mayank, Lessard, Darleen M., Donahue, J. Kevin, Barton, Bruce A., Aurigemma, Gerard P., Mandapati, Amiya, Freedman, Jane E., McManus, David D.
المساهمون: Department of Population and Quantitative Health Sciences, Division of Cardiovascular Medicine, Department of Medicine
المصدر: PloS one ; 15 ; 8 ; e0236960
مصطلحات موضوعية: MicroRNAs, Atrial fibrillation, Blood plasma, Cardiovascular disease risk, Apoptosis, Phenotypes, Fibrosis, Gene expression, UMCCTS funding, Cardiology, Cardiovascular Diseases, Circulatory and Respiratory Physiology, Nucleic Acids, Nucleotides, and Nucleosides
Relation: Link to Article in PubMed; Vaze A, Tran KV, Tanriverdi K, Sardana M, Lessard D, Donahue JK, Barton B, Aurigemma G, Lubitz SA, Lin H, Nasr GH, Mandapati A, Benjamin EJ, Vasan RS, Freedman JE, McManus DD. Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study. PLoS One. 2020 Aug 19;15(8):e0236960. doi:10.1371/journal.pone.0236960. PMID: 32813736; PMCID: PMC7437902. Link to article on publisher's site; 1932-6203 (Linking); http://hdl.handle.net/20.500.14038/41551; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5367&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/4340; oapubs/4340
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18Academic Journal
المؤلفون: Marino, Francesca, Lessard, Darleen M., Saczynski, Jane S., McManus, David D., Silverman-Lloyd, Luke G., Benson, Christopher M., Blaha, Michael J., Waring, Molly E.
المساهمون: Department of Population and Quantitative Health Sciences, Division of Cardiovascular Medicine, Department of Medicine
المصدر: Journal of the American Heart Association ; 8 ; 22 ; e013212
مصطلحات موضوعية: anxiety, atrial fibrillation, cognition, depression, quality of life, Cardiology, Cardiovascular Diseases, Geriatrics, Musculoskeletal, Neural, and Ocular Physiology, Psychiatry and Psychology, Psychological Phenomena and Processes
Relation: Link to Article in PubMed; J Am Heart Assoc. 2019 Nov 19;8(22):e013212. doi:10.1161/JAHA.119.013212. Epub 2019 Nov 16. Link to article on publisher's site; 2047-9980 (Linking); http://hdl.handle.net/20.500.14038/41259; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5065&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/4046; oapubs/4046
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19Academic Journal
المؤلفون: Tran, Khanh-Van T., Tanriverdi, Kahraman, Aurigemma, Gerard P., Lessard, Darleen M., Sardana, Mayank, Parker, Matthew, Shaikh, Amir Y., Gottbrecht, Matthew, Milstone, Zachary, Tanriverdi, Selim E., Vitseva, Olga, Keaney, John F. Jr., Kiefe, Catarina I., McManus, David D., Freedman, Jane E.
المساهمون: Graduate School of Biomedical Sciences, Department of Population and Quantitative Health Sciences, Department of Medicine, Division of Cardiovascular Medicine
المصدر: Journal of clinical and translational research ; 5 ; 1 ; 33-43
مصطلحات موضوعية: Biomarkers, Cardiac remodelling, Echocardiographic phenotypes, Extracellular RNAs, Heart failure, Analytical, Diagnostic and Therapeutic Techniques and Equipment, Biological Factors, Cardiology, Cardiovascular Diseases, Cardiovascular System, Nucleic Acids, Nucleotides, and Nucleosides, Translational Medical Research
Relation: Link to Article in PubMed; J Clin Transl Res. 2019 Jun 8;5(1):33-43. eCollection 2019 Sep 8.; 2382-6533 (Linking); http://hdl.handle.net/20.500.14038/41198; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5003&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3986; oapubs/3986
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20Academic Journal
المؤلفون: Abu, Hawa Ozien, McManus, David D., Lessard, Darleen M., Kiefe, Catarina I., Goldberg, Robert J.
المساهمون: Department of Medicine, Division of Cardiovascular Medicine, Department of Population and Quantitative Health Sciences
المصدر: Health and quality of life outcomes ; 17 ; 1 ; 149
مصطلحات موضوعية: Acute coronary syndrome, Lifestyle, Quality of life, Religion, Spirituality, Cardiology, Cardiovascular Diseases, Clinical Epidemiology, Epidemiology, Health Services Administration, Psychological Phenomena and Processes
Relation: Link to Article in PubMed; https://doi.org/10.1186/s12955-019-1218-6; Health Qual Life Outcomes. 2019 Sep 3;17(1):149. doi:10.1186/s12955-019-1218-6. Link to article on publisher's site; 1477-7525 (Linking); http://hdl.handle.net/20.500.14038/41194; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4998&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3981; oapubs/3981