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1Academic Journal
المؤلفون: Nicola Laurieri, Julien Dairou, James E Egleton, Lesley A Stanley, Angela J Russell, Jean-Marie Dupret, Edith Sim, Fernando Rodrigues-Lima
المصدر: PLoS ONE, Vol 9, Iss 5, p e96370 (2014)
وصف الملف: electronic resource
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2
المؤلفون: Lesley A, Stanley, C Roland, Wolf
المصدر: Drug Metabolism Reviews. 54:46-62
مصطلحات موضوعية: Proteomics, Metabolic Clearance Rate, Hepatocytes, Cytochrome P-450 CYP3A, Humans, Pharmacology (medical), Hep G2 Cells, General Pharmacology, Toxicology and Pharmaceutics, Cell Line
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3
المؤلفون: Lesley A. Stanley, Edith Sim
المصدر: Arylamine N-acetyltransferases in Health and Disease
مصطلحات موضوعية: Embryogenesis, Acetyltransferases, Biology, Cell biology
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4
المؤلفون: Colin J. Henderson, Amy R. Cameron, Lynsey R. Chatham, Lesley A. Stanley, Charles Roland Wolf
المصدر: Toxicological Sciences
مصطلحات موضوعية: transgenic mice, Toxicology, medicine.disease_cause, chemistry.chemical_compound, Mice, medicine, Animals, Promoter Regions, Genetic, Carcinogen, Cyproterone acetate, heme oxygenase-1, Nafenopin, 3. Good health, Mice, Inbred C57BL, Oxidative Stress, medicine.anatomical_structure, chemistry, Biochemistry, Hepatocyte, Cancer research, Carcinogens, Phenobarbital, Oxidative Stress Unable to Explain Actions of all Nongenotoxic Carcinogens, Thioacetamide, Carcinogenesis, nongenotoxic carcinogens, Oxidative stress, medicine.drug
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5
المؤلفون: Nancy Claude, Brigitte Lindeman, Werner Brueller, Helen Håkansson, Isabelle Leconte, Jyrki Liesivuori, Corrado L. Galli, Leda Kovatsi, Joana P. Miranda, Rolf Schulte-Hermann, Emma Martínez-López, Lesley A. Stanley, Bas J. Blaauboer, Cécile Michel, Aristidis Tsatsakis, Martin F. Wilks, Philippe Bourrinet, Vesna Matović, Marek Murias, Eva Cecilie Bonefeld-Jørgensen, Johanna Zilliacus, Ursula Gundert-Remy, Heather M. Wallace, Dominique Lison, Paul T.J. Scheepers, João Paulo Teixeira, Marie Haag-Grönlund, Nurşen Başaran
المصدر: Toxicology Letters, 259, 151-5
Toxicology Letters, 259, pp. 151-5
Wilks, M F, Blaauboer, B J, Schulte-Hermann, R, Wallace, H M, Galli, C L, Haag-Grönlund, M, Matović, V, Teixeira, J P, Zilliacus, J, Basaran, N, Bonefeld-Jørgensen, E C, Bourrinet, P, Brueller, W, Claude, N, Miranda, J P, Gundert-Remy, U, Håkansson, H, Kovatsi, L, Liesivuori, J, Lindeman, B, Lison, D, Leconte, I, Martínez-López, E, Murias, M, Michel, C, Scheepers, P T J, Stanley, L & Tsatsakis, A 2016, ' The European Registered Toxicologist (ERT) : Current status and prospects for advancement ', Toxicology Letters, vol. 259, pp. 151-5 . https://doi.org/10.1016/j.toxlet.2016.06.014مصطلحات موضوعية: 0301 basic medicine, Certification, Education, Continuing, Process (engineering), Best practice, Audit, 010501 environmental sciences, Toxicology, European Registered Toxicologist, 01 natural sciences, Scientific integrity, 03 medical and health sciences, Professional Competence, EUROTOX, Credibility, Journal Article, Medicine, Humans, Education, Graduate, Toxicologia, ta317, 0105 earth and related environmental sciences, business.industry, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Cornerstone, General Medicine, Europe, 030104 developmental biology, Continuing professional development, Engineering ethics, ERT, business
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6
المؤلفون: C. Roland Wolf, Lesley A. Stanley, Brian C. Horsburgh, Nico Scheer, Jillian Ross
المصدر: Drug Metabolism Reviews. 41:27-65
مصطلحات موضوعية: Biological Availability, Pharmacology, Models, Biological, Xenobiotics, chemistry.chemical_compound, In vivo, Animals, Humans, Distribution (pharmacology), Tissue Distribution, Pharmacology (medical), General Pharmacology, Toxicology and Pharmaceutics, Cells, Cultured, P-glycoprotein, Membranes, biology, Multidrug resistance-associated protein 2, Biological Transport, Transporter, Cell Compartmentation, Cell biology, Liver, chemistry, Blood-Brain Barrier, Models, Animal, biology.protein, ATP-Binding Cassette Transporters, Efflux, Xenobiotic, Function (biology)
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7
المؤلفون: Edith Sim, Lesley A. Stanley
المصدر: Pharmacogenomics. 9:1673-1693
مصطلحات موضوعية: Models, Molecular, Pharmacology, Genetics, Protein Folding, education.field_of_study, Polymorphism, Genetic, Arylamine N-acetyltransferase, Arylamine N-Acetyltransferase, fungi, Population, Cellular homeostasis, Biology, Phenotype, Gene Expression Regulation, Enzymologic, Genetics, Population, Protein structure, Nat, Pharmacogenomics, Animals, Humans, Molecular Medicine, Neural Tube Defects, education, Gene
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8
المؤلفون: Lesley A. Stanley, C. Roland Wolf, Nico Scheer, Brian C. Horsburgh, Jillian Ross
المصدر: Drug Metabolism Reviews. 38:515-597
مصطلحات موضوعية: Receptors, Steroid, Pregnane X receptor, Drug-Related Side Effects and Adverse Reactions, Chemistry, Pregnane X Receptor, In vitro toxicology, Receptors, Cytoplasmic and Nuclear, Pharmacology, Gene Expression Regulation, Enzymologic, Xenobiotics, Cell biology, Cytochrome P-450 Enzyme System, Drug development, Nuclear receptor, In vivo, Humanized mouse, Constitutive androstane receptor, Hepatocytes, Animals, Humans, Pharmacology (medical), General Pharmacology, Toxicology and Pharmaceutics, Receptor, Constitutive Androstane Receptor, Transcription Factors
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9
المؤلفون: Edward Doyle, Robert Powrie, Lesley A. Stanley, Diane D’Angelo, Clifford R. Elcombe, Julie A. Skare
المصدر: Toxicology. 210:147-157
مصطلحات موضوعية: Male, medicine.medical_specialty, Phenylenediamines, Biology, urologic and male genital diseases, Toxicology, Mass Spectrometry, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Internal medicine, medicine, Humans, Cells, Cultured, Chromatography, High Pressure Liquid, Carcinogen, chemistry.chemical_classification, Fluorenes, Bladder cancer, Cytochrome P450, p-Phenylenediamine, Acetylation, Metabolism, medicine.disease, Recombinant Proteins, Enzyme, Endocrinology, chemistry, Hepatocytes, Microsomes, Liver, biology.protein, Microsome, Drug metabolism, Protein Binding
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10
المصدر: Molecular pharmacology. 87(4)
مصطلحات موضوعية: Male, CYP2D6, Cytochrome, Nifedipine, Pharmacology, chemistry.chemical_compound, Sex Factors, In vivo, Animals, Cytochrome P-450 CYP3A, Humans, Mice, Knockout, biology, CYP3A4, Bufuralol, Cytochrome P450, Triazolam, Debrisoquin, Cytochromes b5, chemistry, Debrisoquine, Cytochrome P-450 CYP2D6, Ethanolamines, biology.protein, Microsome, Microsomes, Liver, Molecular Medicine, Female
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11
المؤلفون: Lesley A Stanley, Richard D. Verschoyle, Joan Riley, Ian N.H. White, Jerry Styles, Timothy W. Gant
المصدر: Biochemical Pharmacology. 60:233-239
مصطلحات موضوعية: medicine.medical_specialty, Antineoplastic Agents, Hormonal, Metabolic Clearance Rate, ATPase, Gene Expression, Biochemistry, Excretion, Internal medicine, Gene expression, medicine, Animals, ATP Binding Cassette Transporter, Subfamily B, Member 1, skin and connective tissue diseases, P-glycoprotein, Pharmacology, biology, Bile Canaliculi, Antiestrogen, Rats, Tamoxifen, medicine.anatomical_structure, Real-time polymerase chain reaction, Endocrinology, Liver, Rats, Inbred Lew, Hepatocyte, biology.protein, medicine.drug
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12
المؤلفون: Edith Sim, Alison Jones, Lesley A. Stanley
المصدر: Acta Pharmacologica et Toxicologica. 57:304-306
مصطلحات موضوعية: Pharmacology, biology, Urease, Chemistry, Guinea Pigs, Covalent binding, Complement C4, Complement C3, Metabolism, Hydroxamic Acids, Toxicology, Complement system, Biochemistry, Enzyme inhibitor, biology.protein, Animals, Humans, Lupus Erythematosus, Systemic, Biological sciences, Protein Binding
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13
المؤلفون: P. Nicholas Shaw, Mei-Sze Chua, Ian Hutchinson, and Lesley A. Stanley, Samantha Wrigley, Dong-Fang Shi, Tracey D. Bradshaw, David A. Barrett, Malcolm F. G. Stevens
المصدر: Journal of Medicinal Chemistry. 42:381-392
مصطلحات موضوعية: Male, Magnetic Resonance Spectroscopy, Spectrophotometry, Infrared, Antineoplastic Agents, Chemical synthesis, Biotransformation, Acetyltransferases, In vivo, Drug Discovery, Tumor Cells, Cultured, medicine, Animals, Humans, Amines, Rats, Wistar, Cytotoxicity, Microscopy, Confocal, Chemistry, Acetylation, In vitro, Rats, Thiazoles, Mechanism of action, Biochemistry, Cell culture, Molecular Medicine, medicine.symptom
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14
المؤلفون: Lesley A. Stanley, Jean-Marie Dupret, Julien Dairou, Angela J. Russell, Nicola Laurieri, Fernando Rodrigues-Lima, James E. Egleton, Edith Sim
المصدر: PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e96370 (2014)
PloS ONEمصطلحات موضوعية: Embryology, Arylamine N-Acetyltransferase, lcsh:Medicine, Biochemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, Basic Cancer Research, Medicine and Health Sciences, Morphogenesis, lcsh:Science, Enzyme Chemistry, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Arylamine N-acetyltransferase, Hydrolysis, Cancer Risk Factors, Acetylation, Naphthoquinone, Enzymes, Isoenzymes, Oncology, 030220 oncology & carcinogenesis, Research Article, Biotechnology, alliedhealth, Acetyl-CoA Hydrolase, Cofactor, 03 medical and health sciences, Folic Acid, Acetyltransferases, Animals, Humans, Birth Defects, Nuclear Magnetic Resonance, Biomolecular, 030304 developmental biology, lcsh:R, Active site, Biology and Life Sciences, Acetyl-CoA hydrolase, Enzyme assay, Enzyme, chemistry, Small Molecules, biology.protein, Enzymology, Cofactors (Biochemistry), lcsh:Q, Developmental Biology
وصف الملف: application/pdf
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15
المؤلفون: Ian G. Mills, Edith Sim, Lesley A. Stanley
المصدر: Pharmacogenetics. 7:121-130
مصطلحات موضوعية: Arylamine N-Acetyltransferase, Mice, Inbred Strains, Spleen, Biology, Isozyme, law.invention, Mice, Cytosol, Antigen, law, Genetics, medicine, Animals, Tissue Distribution, General Pharmacology, Toxicology and Pharmaceutics, Antiserum, Polymorphism, Genetic, Acetylation, Immunohistochemistry, Molecular biology, Small intestine, Staining, Isoenzymes, medicine.anatomical_structure, Liver, Biochemistry, Polyclonal antibodies, Recombinant DNA, biology.protein
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16
المؤلفون: Lesley A. Stanley, Edith Sim, Peter M. M. Thygesen, Angela Risch, Nada Matas, Michael W. Stacey
المصدر: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 1(1)
مصطلحات موضوعية: Yeast artificial chromosome, Bladder cancer, Arylamine N-acetyltransferase, Health, Toxicology and Mutagenesis, Clinical Biochemistry, Chromosome, In situ hybridization, Biology, medicine.disease, Biochemistry, Isozyme, Molecular biology, Cosmid, medicine, Metaphase
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17
المؤلفون: Valerie Smelt, Edith Sim, A Ward, Lesley A. Stanley, D Lane, W van der Slot, Angela Risch
المصدر: ResearcherID
مصطلحات موضوعية: Adult, medicine.medical_specialty, Erythrocytes, Pancreatic disease, Adolescent, Cystic Fibrosis, Sulfamethoxazole, Arylamine N-Acetyltransferase, Health, Toxicology and Mutagenesis, Biology, Toxicology, Polymerase Chain Reaction, Cystic fibrosis, Isozyme, Anti-Infective Agents, Fibrosis, Internal medicine, medicine, Humans, Allele, Alleles, Pharmacology, Arylamine N-acetyltransferase, medicine.disease, Isoenzymes, Red blood cell, medicine.anatomical_structure, Endocrinology, Mutation, Polymorphism, Restriction Fragment Length, Pharmacogenetics
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18
المؤلفون: Peter M. M. Thygesen, Angela Risch, Lesley A. Stanley, Edith Sim
المصدر: Trends in Genetics. 11:509-512
مصطلحات موضوعية: Genetics, Smoking, Multifactorial disease, Genetic Diseases, Inborn, Parkinson Disease, Polygenic disease, Environmental exposure, Biology, Autoimmune Diseases, Disease susceptibility, Urinary Bladder Neoplasms, Homogeneous, Animals, Humans, Genetic Predisposition to Disease, Identification (biology)
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19
المؤلفون: Lesley A. Stanley
المصدر: Toxicology. 96:173-194
مصطلحات موضوعية: Lung Neoplasms, Skin Neoplasms, Tumor suppressor gene, Molecular Sequence Data, Mammary gland, Biology, Toxicology, medicine.disease_cause, law.invention, Mice, Liver Neoplasms, Experimental, law, medicine, Animals, Humans, Genes, Tumor Suppressor, Codon, Gene, Carcinogen, Genetics, Regulation of gene expression, Base Sequence, Oncogene, Mammary Neoplasms, Experimental, Neoplasms, Experimental, Oncogenes, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Genes, ras, medicine.anatomical_structure, Mutation, Carcinogens, Cancer research, Suppressor, Carcinogenesis
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20
المؤلفون: Anja Rode, Vincent Beuger, Yury Kapelyukh, Jillian McEwan, Nico Scheer, C. Roland Wolf, Lesley A. Stanley
المصدر: Molecular pharmacology. 81(1)
مصطلحات موضوعية: Genetically modified mouse, CYP2D6, Transgene, Population, Mice, Transgenic, Biology, digestive system, Cell Line, Mice, Gene cluster, Animals, Humans, Drug Interactions, skin and connective tissue diseases, education, Alleles, Embryonic Stem Cells, Pharmacology, Genetics, Mice, Knockout, education.field_of_study, Mice, Inbred BALB C, Genetic Variation, Mice, Inbred C57BL, Cytochrome P-450 CYP2D6, Humanized mouse, Knockout mouse, Models, Animal, Molecular Medicine, Drug metabolism
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