المؤلفون: David B. Huang, Leonard R. Duncan, Yahse K. Edah, Paul R. Rhomberg, Robert K. Flamm, Michael D. Huband

المصدر: Journal of Global Antimicrobial Resistance, Vol 25, Iss , Pp 14-17 (2021)

مصطلحات موضوعية: Iclaprim, Listeria monocytogenes, In vitro, Bloodstream infection, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213716521000473; https://doaj.org/toc/2213-7165

URL الوصول: https://doaj.org/article/35ba935f16e04570a03426ec828258a0

المؤلفون: Helio S. Sader, Mariana Castanheira, Leonard R. Duncan, Rodrigo E. Mendes

المصدر: International Journal of Infectious Diseases, Vol 113, Iss , Pp 279-281 (2021)

مصطلحات موضوعية: Pseudomonas aeruginosa, ceftazidime/avibactam, ceftolozane/tazobactam, imipenem/relebactam, meropenem/vaborbactam, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971221008092; https://doaj.org/toc/1201-9712

URL الوصول: https://doaj.org/article/bf9c27dc44894de6a4e64077bcd0288a

المؤلفون: Leonard R. Duncan, Caitlin J. Smith, Robert K. Flamm, Rodrigo E. Mendes

المصدر: Journal of Global Antimicrobial Resistance, Vol 20, Iss , Pp 118-123 (2020)

مصطلحات موضوعية: Multidrug-resistant, Methicillin-resistant Staphylococcus aureus (MRSA), Census division, Surveillance, Lipoglycopeptide, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213716519301730; https://doaj.org/toc/2213-7165

URL الوصول: https://doaj.org/article/8d6443b4e9a841ee93fd98bb823a0c02

المؤلفون: Helio S. Sader, Leonard R. Duncan, Rodrigo E. Mendes

المصدر: International Journal of Infectious Diseases, Vol 107, Iss , Pp 69-71 (2021)

مصطلحات موضوعية: Cystic fibrosis, Pneumonia, Staphylococcus aureus, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971221003623; https://doaj.org/toc/1201-9712

URL الوصول: https://doaj.org/article/c76fc1d89024419c8cb4b0569ee2f118

المؤلفون: Janna Michaeli, Shira Mandel, Shelly Maximov, Jonathan Zazoun, Paola Savoia, Nimmi Kothari, Thomas Valmont, Livia Ferrari, Leonard R. Duncan, Stephen Hawser, Moshe Cohen-Kutner, Niv Bachnoff

المصدر: Antibiotics, Vol 11, Iss 9, p 1201 (2022)

مصطلحات موضوعية: OMN6, antimicrobial peptides, antimicrobial resistance, AMR, Acinetobacter baumannii, infectious diseases, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2079-6382/11/9/1201; https://doaj.org/toc/2079-6382

URL الوصول: https://doaj.org/article/809ab2780cbf4901bed304c58b21b023

المؤلفون: Yanran Lu (6686399), Sandip Vibhute (2563972), Linsen Li (548722), Antony Okumu (11530664), Steven C. Ratigan (9279098), Sheri Nolan (6686393), Jonathan L. Papa (9537544), Chelsea A. Mann (11530667), Anthony English (6686396), Anna Chen (424723), Justin T. Seffernick (5030693), Bryan Koci (11530670), Leonard R. Duncan (11530673), Brieanna Roth (11530676), Jason E. Cummings (2803606), Richard A. Slayden (552399), Steffen Lindert (115057), Craig A. McElroy (2355709), Daniel J. Wozniak (8968187), Jack Yalowich (9537553), Mark J. Mitton-Fry (1936516)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new antibiotics, potent antistaphylococcal activity, microsomal metabolic stability, key safety liability, cardiovascular safety profile, 5 ‑ amino, previously reported dioxane, focused optimization enabled, reduced herg inhibition, herg inhibition, vivo <, vitro <, topoiv potency, topoisomerase iv, positive pathogens, murine model, low frequency, dna gyrase

Relation: https://figshare.com/articles/journal_contribution/Optimization_of_TopoIV_Potency_ADMET_Properties_and_hERG_Inhibition_of_5_Amino-1_3-dioxane-Linked_Novel_Bacterial_Topoisomerase_Inhibitors_Identification_of_a_Lead_with_i_In_Vivo_i_Efficacy_against_MRSA/16755332

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01250.s007

المؤلفون: Helio S Sader, Rodrigo E Mendes, Leonard R Duncan, Cecilia G Carvalhaes, Mariana Castanheria

المصدر: Journal of Antimicrobial Chemotherapy. 77:2642-2649

مصطلحات موضوعية: Pharmacology, Microbiology (medical), Tazobactam, Lactams, Microbial Sensitivity Tests, Ceftazidime, Anti-Bacterial Agents, Cephalosporins, Cyclooctanes, Hydrazines, Infectious Diseases, Carbapenems, Enterobacteriaceae, Piperidines, Gram-Negative Bacteria, Pseudomonas aeruginosa, Pharmacology (medical), Cefepime, Azabicyclo Compounds

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b81d848ad3fcc50321c9d5083ad9f7
https://doi.org/10.1093/jac/dkac233

المؤلفون: Lucero Martínez-Fructuoso, S. J. Ryan Arends, Vitor F. Freire, Jason R. Evans, Sean DeVries, Brian D. Peyser, Rhone K. Akee, Christopher C. Thornburg, Rohitesh Kumar, Susan Ensel, Gina M. Morgan, Grant D. McConachie, Nathan Veeder, Leonard R. Duncan, Tanja Grkovic, Barry R. O’Keefe

المصدر: ACS Infectious Diseases.

مصطلحات موضوعية: Infectious Diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dce84210a437cafaa509aa4155384845
https://doi.org/10.1021/acsinfecdis.3c00067

المؤلفون: Helio S Sader, Rodrigo E Mendes, Dee Shortridge, Leonard R Duncan, Valerie Kantro, Mariana Castanheira

المصدر: Open Forum Infectious Diseases. 9

مصطلحات موضوعية: Infectious Diseases, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1b382a31d3721b8c89ab4bd87356786c
https://doi.org/10.1093/ofid/ofac492.1315

المؤلفون: Helio S Sader, Leonard R Duncan, Rodrigo E Mendes, Mariana Castanheira

المصدر: Open Forum Infectious Diseases. 9

مصطلحات موضوعية: Infectious Diseases, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::369018a2fc8d711f35c863d798fa77e7
https://doi.org/10.1093/ofid/ofac492.1316

المؤلفون: Helio S Sader, Cecilia G Carvalhaes, Dee Shortridge, Leonard R Duncan, Mariana Castanheira

المصدر: Open Forum Infectious Diseases. 9

مصطلحات موضوعية: Infectious Diseases, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::445d7ced337d1cff9f32d4faa1165440
https://doi.org/10.1093/ofid/ofac492.1141

المؤلفون: Linsen Li, Steffen Lindert, Yanran Lu, Anna Chen, Jason E. Cummings, Chelsea A Mann, Sandip Vibhute, Brieanna Roth, Anthony English, Sheri Nolan, Mark J. Mitton-Fry, Daniel J. Wozniak, Steven C Ratigan, Richard A. Slayden, Jack C. Yalowich, Bryan Koci, Antony A. Okumu, Jonathan L. Papa, Craig A. McElroy, Justin T Seffernick, Leonard R Duncan

المصدر: Journal of Medicinal Chemistry. 64:15214-15249

مصطلحات موضوعية: biology, medicine.drug_class, Chemistry, Topoisomerase IV, Antibiotics, hERG, Pharmacology, DNA gyrase, In vitro, In vivo, Drug Discovery, medicine, biology.protein, Molecular Medicine, Potency, Topoisomerase inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b3892c880ddb3b3758eba4c921a02b47
https://doi.org/10.1021/acs.jmedchem.1c01250

المؤلفون: Leonard R. Duncan, Helio S. Sader, Michael D. Huband, Robert K. Flamm, Rodrigo E. Mendes

المصدر: Microbial Drug Resistance. 26:934-943

مصطلحات موضوعية: Microbiology (medical), Pharmacology, 0303 health sciences, Lipoglycopeptide, 030306 microbiology, Immunology, Biology, Antimicrobial, Microbiology, In vitro, Multiple drug resistance, 03 medical and health sciences, chemistry.chemical_compound, Telavancin, chemistry, medicine, 030304 developmental biology, medicine.drug, Gram

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e30ed69bb5c638ad43ffcb3b495e5666
https://doi.org/10.1089/mdr.2019.0104

المؤلفون: Leonard R. Duncan, Wen Wang, Helio S. Sader

المصدر: Antimicrob Agents Chemother

مصطلحات موضوعية: Pharmacology, Infectious Diseases, Susceptibility, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de33e8ef4823d64a3bf6afaf3049e63
https://doi.org/10.1128/aac.00139-22

المؤلفون: Helio S. Sader, Mariana Castanheira, Leonard R. Duncan, Rodrigo E. Mendes

المصدر: Diagnostic microbiology and infectious disease. 105(1)

مصطلحات موضوعية: Microbiology (medical), Methicillin-Resistant Staphylococcus aureus, Staphylococcus aureus, Infectious Diseases, Humans, General Medicine, Microbial Sensitivity Tests, Staphylococcal Infections, United States, Hospitals, Anti-Bacterial Agents, Cephalosporins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d585ad562ab022821fbe52a2525e7c
https://pubmed.ncbi.nlm.nih.gov/36274343

المؤلفون: Yanran, Lu, Sandip, Vibhute, Linsen, Li, Antony, Okumu, Steven C, Ratigan, Sheri, Nolan, Jonathan L, Papa, Chelsea A, Mann, Anthony, English, Anna, Chen, Justin T, Seffernick, Bryan, Koci, Leonard R, Duncan, Brieanna, Roth, Jason E, Cummings, Richard A, Slayden, Steffen, Lindert, Craig A, McElroy, Daniel J, Wozniak, Jack, Yalowich, Mark J, Mitton-Fry

المصدر: Journal of medicinal chemistry. 64(20)

مصطلحات موضوعية: DNA Topoisomerase IV, Dioxanes, Methicillin-Resistant Staphylococcus aureus, Structure-Activity Relationship, Dose-Response Relationship, Drug, Molecular Structure, DNA Gyrase, Humans, Microbial Sensitivity Tests, Enzyme Inhibitors, Ether-A-Go-Go Potassium Channels, Anti-Bacterial Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dc8f7442e2cb53241c3d17ad1ee5eb4c
https://pubmed.ncbi.nlm.nih.gov/34614347

المؤلفون: Hans H. Locher, Paul R. Rhomberg, Glenn E. Dale, Leonard R. Duncan, Robert K. Flamm, Helio S. Sader

المصدر: Journal of Antimicrobial Chemotherapy. 75:1518-1524

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Fastidious organism, Asia, medicine.drug_class, 030106 microbiology, Antibiotics, Microbial Sensitivity Tests, Drug resistance, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, medicine, Pharmacology (medical), 030212 general & internal medicine, Pharmacology, biology, Broth microdilution, biology.organism_classification, Antimicrobial, Anti-Bacterial Agents, Acinetobacter baumannii, Europe, Stenotrophomonas maltophilia, Latin America, Infectious Diseases, Colistin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b2be18d1f7bc3760f8a4b7b7e1a393
https://doi.org/10.1093/jac/dkaa020

المؤلفون: Michael A. Pfaller, Robert K. Flamm, Leonard R. Duncan, Dee Shortridge

المصدر: International Journal of Antimicrobial Agents. 53:637-643

مصطلحات موضوعية: Male, 0301 basic medicine, Klebsiella pneumoniae, Cephalosporin, Antibiotics, medicine.disease_cause, 0302 clinical medicine, polycyclic compounds, Pharmacology (medical), Prospective Studies, 030212 general & internal medicine, Child, biology, Broth microdilution, General Medicine, Hospitals, Anti-Bacterial Agents, Europe, Infectious Diseases, Amikacin, Child, Preschool, Female, beta-Lactamase Inhibitors, medicine.drug, Microbiology (medical), Tazobactam, medicine.medical_specialty, Adolescent, medicine.drug_class, 030106 microbiology, Microbial Sensitivity Tests, Meropenem, 03 medical and health sciences, Internal medicine, Gram-Negative Bacteria, medicine, Humans, Pseudomonas aeruginosa, business.industry, Infant, Newborn, Infant, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, biology.organism_classification, United States, Cephalosporins, Colistin, bacteria, Gram-Negative Bacterial Infections, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70744328d76a4eec5258502a3bfa6512
https://doi.org/10.1016/j.ijantimicag.2019.01.015

المؤلفون: Leonard R. Duncan, Kamal A. Hamed, Jennifer I. Smart, Michael A. Pfaller, Robert K. Flamm, Rodrigo E. Mendes

المصدر: Diagnostic microbiology and infectious disease. 103(3)

مصطلحات موضوعية: Microbiology (medical), Methicillin-Resistant Staphylococcus aureus, Arthritis, Infectious, Staphylococcus aureus, Infectious Diseases, Gram-Negative Bacteria, Humans, General Medicine, Microbial Sensitivity Tests, Gram-Positive Bacteria, United States, Anti-Bacterial Agents, Cephalosporins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbb78e6f17cab865b8780c5bbee402a
https://pubmed.ncbi.nlm.nih.gov/35598410

المؤلفون: M Castanheira, Leonard R. Duncan, Timothy B Doyle, Helio S. Sader

المصدر: JAC-Antimicrobial Resistance. 3

مصطلحات موضوعية: business.industry, Avibactam, Ceftazidime, Ceftazidime/avibactam, Tazobactam, Meropenem, Microbiology, chemistry.chemical_compound, chemistry, Piperacillin/tazobactam, polycyclic compounds, medicine, Ceftolozane, business, medicine.drug, Piperacillin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::33782c46cfa57b6d32e9549684a2d132
https://doi.org/10.1093/jacamr/dlab126