المؤلفون: S. Tomlinson, Carina Ämmälä, Patrik Rorsman, Leonard Best

مصطلحات موضوعية: Intracellular pH, Biophysics, chemistry.chemical_element, Stimulation, Acetates, Calcium, Biochemistry, Ammonium Chloride, Membrane Potentials, Cytosol, Tumor Cells, Cultured, Animals, Lactic Acid, Membrane potential, biology, Electric Conductivity, Cell Biology, Hydrogen-Ion Concentration, Membrane transport, chemistry, Lactates, biology.protein, Insulinoma, Beta cell, Intracellular, Organic anion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfd30f43fd4cfe9e06984c7d8714e24
https://ora.ox.ac.uk/objects/uuid:fb802bd2-89d9-4edf-97e6-494aa1ebbcbf

المؤلفون: Leonard Best, Abdullah Sener, Willy Malaisse, Peter de Nully Brown

المصدر: European Journal of Pharmacology. 629:159-163

مصطلحات موضوعية: Male, medicine.medical_specialty, Indoles, Patch-Clamp Techniques, Inhibitory postsynaptic potential, Membrane Potentials, Ion, Rats, Sprague-Dawley, KATP Channels, Katp channels, Insulin-Secreting Cells, Internal medicine, medicine, Animals, Voltage-Dependent Anion Channels, Patch clamp, Cell Size, Pharmacology, Membrane potential, Chemistry, Activator (genetics), Electric Conductivity, Conductance, Oxindoles, Rats, Endocrinology, Biophysics, Female, Tenidap, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efe420df91a4bbd04ec60c4a1577cf9
https://doi.org/10.1016/j.ejphar.2009.12.013

المؤلفون: Abdullah Sener, Myrna Virreira, Jason Perret, Renaud Beauwens, Allen P. Yates, Willy Malaisse, Leonard Best, Christine Delporte, Peter de Nully Brown

المصدر: Cellular Physiology and Biochemistry. 23:255-264

مصطلحات موضوعية: Glycerol, Physiology, Aquaporin, Aquaporins, Membrane Potentials, chemistry.chemical_compound, Insulin-Secreting Cells, Insulin Secretion, Cell polarity, Animals, Insulin, Urea, Voltage-Dependent Anion Channels, skin and connective tissue diseases, geography, geography.geographical_feature_category, Chemistry, Cell Polarity, Islet, Rats, Urea transport, Membrane, Biochemistry, Permeability (electromagnetism), Biophysics, sense organs, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582fb8e42c17ce0b04c2810ea0245d19
https://doi.org/10.1159/000218172

المؤلفون: Allen P. Yates, Leonard Best, Gavin P. Reynolds

المصدر: Journal of Psychopharmacology. 19:597-601

مصطلحات موضوعية: medicine.medical_specialty, Potassium Channels, medicine.drug_class, medicine.medical_treatment, Atypical antipsychotic, Pharmacology, Membrane Potentials, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Internal medicine, Insulin Secretion, Haloperidol, medicine, Animals, Insulin, Pharmacology (medical), Antipsychotic, Clozapine, Cells, Cultured, Pancreatic hormone, Dose-Response Relationship, Drug, business.industry, Dopamine antagonist, Depolarization, Rats, 030227 psychiatry, Psychiatry and Mental health, Endocrinology, Secretory Rate, business, 030217 neurology & neurosurgery, Antipsychotic Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9434665f0023fa9e0cf384ca90d6f50f
https://doi.org/10.1177/0269881105056641

المؤلفون: Leonard Best

المصدر: Pfl�gers Archiv European Journal of Physiology. 445:97-104

مصطلحات موضوعية: Anions, Male, Physiology, Clinical Biochemistry, 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid, Ion Channels, Islets of Langerhans, Physiology (medical), Diazoxide, medicine, Animals, Channel blocker, Reversal potential, Membrane potential, Chemistry, Estrogen Antagonists, Pipette, Depolarization, Rats, Tamoxifen, Glucose, Biochemistry, Nitrobenzoates, Chloride channel, Biophysics, Tonicity, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c7ee34eea12522ea2ca1da48d777bc
https://doi.org/10.1007/s00424-002-0893-y

المؤلفون: T. Speake, Aneela Majid, Peter de Nully Brown, Leonard Best

المصدر: Pfl�gers Archiv European Journal of Physiology. 442:570-576

مصطلحات موضوعية: medicine.medical_specialty, Sodium-Potassium-Chloride Symporters, Physiology, Hypertonic Solutions, Clinical Biochemistry, Fluorescent Antibody Technique, Gene Expression, Alpha (ethology), Glucagon, Rats, Sprague-Dawley, Islets of Langerhans, Physiology (medical), Internal medicine, medicine, Animals, Solute Carrier Family 12, Member 2, Beta (finance), Receptor, Cell Size, geography, Microscopy, Video, geography.geographical_feature_category, Chemistry, Pancreatic islets, Water-Electrolyte Balance, Islet, Molecular biology, Rats, medicine.anatomical_structure, Endocrinology, Pancreas, Cotransporter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a905d15c36097fe4c920afa30998a2
https://doi.org/10.1007/s004240100566

المؤلفون: Roderick S.P. Benson, Leonard Best, E. A. Sheader

المصدر: Biochemical Pharmacology. 61:1381-1386

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Programmed cell death, Necrosis, Insulin, medicine.medical_treatment, Methylglyoxal, Biology, Biochemistry, chemistry.chemical_compound, Endocrinology, Mechanism of action, chemistry, Apoptosis, Internal medicine, Toxicity, medicine, Cytotoxic T cell, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::115751eabaa3d185447a47344f01ec67
https://doi.org/10.1016/s0006-2952(01)00603-7

المؤلفون: Allen P. Yates, Leonard Best, E. A. Sheader, Peter de Nully Brown

المصدر: Journal of Membrane Biology. 177:169-175

مصطلحات موضوعية: medicine.medical_specialty, Physiology, Tolbutamide, Intracellular pH, medicine.medical_treatment, Biophysics, Stimulation, 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid, In Vitro Techniques, Ion Channels, Membrane Potentials, Rats, Sprague-Dawley, Islets of Langerhans, chemistry.chemical_compound, Internal medicine, Insulin Secretion, medicine, Animals, Insulin, Repolarization, Cell Biology, Hydrogen-Ion Concentration, Rats, Kinetics, Glucose, Endocrinology, chemistry, DIDS, Chloride channel, Calcium, Beta cell, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02215d21f5af6fd566190732f78e8db0
https://doi.org/10.1007/s002320001110

المؤلفون: Leonard Best

المصدر: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1468(1-2):311-319

مصطلحات موضوعية: Islet, Patch-Clamp Techniques, Potassium Channels, Anion channel, Tolbutamide, Biophysics, In Vitro Techniques, Biochemistry, Membrane Potentials, Islets of Langerhans, medicine, Animals, Patch clamp, Pancreatic β-cell, Membrane potential, KATP channel, Dose-Response Relationship, Drug, Chemistry, Input, Electric Conductivity, Conductance, Depolarization, Cell Biology, Anion channel activity, Keto Acids, Potassium channel, Rats, Glucose, Tonicity, Electrical activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f13d76e4139783513ea302b4703d00e

المؤلفون: Aouatif Laghmich, Walter S. Zawalich, Abdullah Sener, María Luisa Villanueva-Peñacarrillo, Willy Malaisse, Dany Mercan, Karim Louchami, Marcel Kadiata, Carmen Sanchez-Soto, Concepción Viñambres, Isabel Valverde, André Herchuelz, Leonard Best, Marcia Hiriart, Hassan Jijakli, Elena Larrieta-Carasco, Olivier Scruel, Elizabeth Olivares

المصدر: American Journal of Physiology-Endocrinology and Metabolism. 275:E993-E1006

مصطلحات موضوعية: medicine.medical_specialty, Physiology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Carbohydrate metabolism, Biology, Phosphatidylinositols, Islets of Langerhans, chemistry.chemical_compound, Cations, Physiology (medical), Internal medicine, Cyclic AMP, medicine, Animals, Insulin, Phosphorylation, Rats, Wistar, geography, geography.geographical_feature_category, Catabolism, Hydrolysis, Intracellular Membranes, Metabolism, Hydrogen-Ion Concentration, Carbohydrate, Islet, Rats, Electrophysiology, Glutamine, Glucose, Endocrinology, Biochemistry, L-Glucose, chemistry, Calcium, Adenylyl Cyclases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e667ecd6be3f704faf59d189dbb0f3
https://doi.org/10.1152/ajpendo.1998.275.6.e993

المؤلفون: Richard Grint, Darren Holden, Leonard Best, Helen E. Miley, Peter de Nully Brown

المصدر: Pfl�gers Archiv European Journal of Physiology. 435:227-230

مصطلحات موضوعية: Male, medicine.medical_specialty, Sodium-Potassium-Chloride Symporters, Physiology, Hypertonic Solutions, Clinical Biochemistry, Cell, Video Recording, 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid, Buffers, Amiloride, Rats, Sprague-Dawley, Islets of Langerhans, chemistry.chemical_compound, Physiology (medical), Internal medicine, medicine, Animals, Mannitol, Diuretics, Receptor, Bumetanide, Cell Size, Rats, Solutions, Bicarbonates, Endocrinology, medicine.anatomical_structure, chemistry, DIDS, Biophysics, Tonicity, Carrier Proteins, Cotransporter, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560cdbf9372c7db3252e28d69382d4b5
https://doi.org/10.1007/s004240050505

المؤلفون: E. A. Sheader, Peter de Nully Brown, Helen E. Miley, Leonard Best

المصدر: The Journal of Physiology. 504:191-198

مصطلحات موضوعية: Male, medicine.medical_specialty, Patch-Clamp Techniques, Physiology, medicine.medical_treatment, In Vitro Techniques, Membrane Potentials, Rats, Sprague-Dawley, Islets of Langerhans, Internal medicine, medicine, Animals, Hexose, Patch clamp, Cell Size, chemistry.chemical_classification, Chemistry, Pancreatic islets, Insulin, Depolarization, Metabolism, Electric Stimulation, Rats, Electrophysiology, Glucose, Endocrinology, medicine.anatomical_structure, Hypotonic Solutions, Tonicity, Calcium, Female, Mannitol, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670efbdc2a89592d7545d683869f2947
https://doi.org/10.1111/j.1469-7793.1997.00191.x

المؤلفون: Hassan Jijakli, Lynda Cook, Abdellatif Bakkali Nadi, Abdullah Sener, Willy Malaisse, Leonard Best

المصدر: Archives of Biochemistry and Biophysics. 335:245-257

مصطلحات موضوعية: Glycerol, Male, Pyruvate decarboxylation, Pyruvate dehydrogenase kinase, Biophysics, Pyruvate dehydrogenase phosphatase, Biology, PKM2, Methylation, Biochemistry, Rats, Sprague-Dawley, Islets of Langerhans, Insulin Secretion, Animals, Insulin, Dihydrolipoyl transacetylase, Pyruvates, Molecular Biology, L-Lactate Dehydrogenase, Methanol, Alanine Transaminase, Hydrogen-Ion Concentration, Pyruvate dehydrogenase complex, Mitochondria, Rats, Pyruvate carboxylase, Glucose, Gluconeogenesis, Extracellular Space

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7012dab0b15bcdf5d2c4386c54d1fe5
https://doi.org/10.1006/abbi.1996.0505

المؤلفون: Sadik Ulusoy, Willy Malaisse, Hassan Jijakli, Lynda Cook, Leonard Best, Isabel Valverde, Abdullah Sener, María Luisa Villanueva-Peñacarrillo, Concepción Viñambres

المصدر: Archives of Biochemistry and Biophysics. 335:229-244

مصطلحات موضوعية: Male, medicine.medical_specialty, Pyruvate dehydrogenase kinase, medicine.medical_treatment, Biophysics, Stimulation, Methylation, Biochemistry, Rats, Sprague-Dawley, Islets of Langerhans, chemistry.chemical_compound, Biosynthesis, Internal medicine, Insulin Secretion, Pyruvic Acid, medicine, Animals, Insulin, Molecular Biology, Proinsulin, Dose-Response Relationship, Drug, Pancreatic islets, Hyperpolarization (biology), Rubidium, Rats, Pyruvate carboxylase, Glucose, Endocrinology, medicine.anatomical_structure, chemistry, Protein Biosynthesis, Calcium, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0fa5946caa0936090bea5ed65be6e0
https://doi.org/10.1006/abbi.1996.0504

المؤلفون: Willy Malaisse, Leonard Best, Abdullah Sener, Peter de Nully Brown

المصدر: Islets. 2(2)

مصطلحات موضوعية: medicine.medical_specialty, Potassium Channels, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Stimulation, Gating, Carbohydrate metabolism, Models, Biological, Membrane Potentials, Islets of Langerhans, Endocrinology, Internal medicine, medicine, Animals, Humans, Cell Size, Membrane potential, Models, Statistical, Chemistry, Insulin, Depolarization, Metabolism, Electrophysiological Phenomena, Glucose, Threshold potential, Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fcbab8f0b4e32448b424d84f3d6633
https://pubmed.ncbi.nlm.nih.gov/21099297

المؤلفون: R. Trebilcock, Leonard Best, S. Tomlinson

المصدر: Molecular and Cellular Endocrinology. 86:49-56

مصطلحات موضوعية: Monocarboxylic Acid Transporters, Lactate transport, endocrine system, medicine.medical_specialty, Cell type, Coumaric Acids, Intracellular pH, Biology, Biochemistry, Amiloride, Islets of Langerhans, Endocrinology, Internal medicine, Insulin Secretion, Tumor Cells, Cultured, medicine, Animals, Insulin, Lactic Acid, Molecular Biology, Insulinoma, Cells, Cultured, B cell, geography, geography.geographical_feature_category, Pancreatic islets, Biological Transport, Depolarization, Hydrogen-Ion Concentration, Islet, medicine.disease, Molecular biology, Rats, Pancreatic Neoplasms, medicine.anatomical_structure, Lactates, Quercetin, Carrier Proteins, 4-Chloromercuribenzenesulfonate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d39972fa5ac85ef71c29b619e68314
https://doi.org/10.1016/0303-7207(92)90174-5

المؤلفون: R. Trebilcock, Leonard Best, S. Tomlinson

المصدر: Bioscience Reports. 12:69-76

مصطلحات موضوعية: endocrine system, medicine.medical_treatment, Biophysics, Biology, Biochemistry, Islets of Langerhans, Insulin Secretion, Tumor Cells, Cultured, medicine, Animals, Insulin, Molecular Biology, Insulinoma, Pancreatic islets, Sodium, Biological Transport, Cell Biology, Metabolism, Hydrogen-Ion Concentration, Membrane transport, medicine.disease, Keto Acids, Rats, medicine.anatomical_structure, Cell culture, Secretagogue, Leucine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d103ac34104f8f96464a079d83a637d
https://doi.org/10.1007/bf01125829

المؤلفون: Angela M. Lynch, S. Tomlinson, Richard Trebilcock, Leonard Best

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1091:141-144

مصطلحات موضوعية: Fluorescence spectrometry, chemistry.chemical_element, Acetates, Calcium, Membrane Potentials, Islets of Langerhans, chemistry.chemical_compound, Cytosol, Tolbutamide, Tumor Cells, Cultured, medicine, Animals, Lactic Acid, Molecular Biology, Ion transporter, Membrane potential, chemistry.chemical_classification, Tetraethylammonium, Depolarization, Isoxazoles, Cell Biology, Hydrogen-Ion Concentration, Fluoresceins, chemistry, Biochemistry, Aminoquinolines, Lactates, Biophysics, Propionate, Insulinoma, Propionates, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649346b1a4dbf8954089dd79303b3ced
https://doi.org/10.1016/0167-4889(91)90053-z

المؤلفون: Leonard Best, Angela M. Lynch

المصدر: Biochemical Pharmacology. 40:411-416

مصطلحات موضوعية: medicine.medical_specialty, β cell function, Sodium-Hydrogen Exchangers, medicine.medical_treatment, Biology, Biochemistry, Islets of Langerhans, chemistry.chemical_compound, Cytosol, Internal medicine, Insulin Secretion, Tumor Cells, Cultured, medicine, Animals, Humans, Insulin, Chloride-Bicarbonate Antiporters, Fluorescein, Pancreatic hormone, Fluorescent Dyes, Acid-Base Equilibrium, Pharmacology, Biological activity, Hydrogen-Ion Concentration, Fluoresceins, Sodium–hydrogen antiporter, Endocrinology, chemistry, Acid–base reaction, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba1531eafcc1bb66feae2418ac565dd
https://doi.org/10.1016/0006-2952(90)90537-u

المؤلفون: Richard Trebilcock, S. Tomlinson, Angela M. Lynch, Leonard Best

المصدر: Molecular and Cellular Endocrinology. 71:21-25

مصطلحات موضوعية: medicine.medical_specialty, 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid, Sodium-Hydrogen Exchangers, Intracellular pH, Sodium, Antiporter, chemistry.chemical_element, 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid, Acetates, Biochemistry, Ammonium Chloride, chemistry.chemical_compound, Endocrinology, Chlorides, Internal medicine, Insulin Secretion, Tumor Cells, Cultured, medicine, Insulin, Lactic Acid, Molecular Biology, Fluorescent Dyes, Hydrogen-Ion Concentration, Adenoma, Islet Cell, Fluoresceins, Amiloride, Lactic acid, Pancreatic Neoplasms, Bicarbonates, Sodium–hydrogen antiporter, chemistry, DIDS, Lactates, Biophysics, Insulinoma, Carrier Proteins, Intracellular, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96d66ebd455e0a7864d97d577356fb7
https://doi.org/10.1016/0303-7207(90)90070-o