المؤلفون: Lenka Jourova, Stefan Satka, Veronika Frybortova, Iveta Zapletalova, Pavel Anzenbacher, Eva Anzenbacherova, Petra Petr Hermanova, Barbora Drabonova, Dagmar Srutkova, Hana Kozakova, Tomas Hudcovic

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: gut–liver axis, butyrate, gut inflammation, drug metabolism, cytochromes P450, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.936013/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/354778228db1423bae3af4090715a4c2

المؤلفون: Eva Anzenbacherova, Alena Spicakova, Lenka Jourova, Jitka Ulrichova, Milan Adamus, Petr Bachleda, Pavel Anzenbacher

المصدر: Journal of Pharmacological Sciences, Vol 127, Iss 2, Pp 190-195 (2015)

مصطلحات موضوعية: Rocuronium, Cytochrome P450, Drug interactions, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861314000279; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/f8af3472dbc4424da2d35aa95eeabef8

المؤلفون: Nina Zemanová, Kateřina Lněničková, Markéta Vavrečková, Eva Anzenbacherová, Pavel Anzenbacher, Iveta Zapletalová, Petra Hermanová, Tomáš Hudcovic, Hana Kozáková, Lenka Jourová

المصدر: PLoS ONE, Vol 16, Iss 11, p e0259643 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e1d09ad3f04e48d69d0322e380371ead

المؤلفون: Lenka Jourová, Marketa Vavreckova, Nina Zemanova, Pavel Anzenbacher, Katerina Langova, Petra Hermanova, Tomas Hudcovic, Eva Anzenbacherova

المصدر: Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: liver cytochromes P450, gut microbiome, sex difference, germ-free mice, metabolism of drugs, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.01303/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/76866270436a451898630733a71cf664

المؤلفون: Veronika Frybortova, Stefan Satka, Lenka Jourova, Iveta Zapletalova, Martin Srejber, Philippe Briolotti, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin, Pavel Anzenbacher, Michal Otyepka, Eva Anzenbacherova

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 7, p 3610 (2024)

مصطلحات موضوعية: phytic acid, IP6, phytates, cytochrome P450, CYP1A, drug metabolism, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/7/3610; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/8882ed7b9225490994babe3a277fa71b

الاتاحة: https://doi.org/10.3390/ijms25073610
https://doaj.org/article/8882ed7b9225490994babe3a277fa71b

المؤلفون: Stefan Satka, Veronika Frybortova, Iveta Zapletalova, Pavel Anzenbacher, Eva Anzenbacherova, Hana Kozakova, Dagmar Srutkova, Tomas Hudcovic, Lenka Jourova

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11627

مصطلحات موضوعية: gut–liver axis, gut inflammation, butyrate, hepatic drug metabolism, cytochromes P450, germ-free mice, microbiome

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms231911627

الاتاحة: https://doi.org/10.3390/ijms231911627

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/journal_contribution/S1_Data_-/16965974

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.s001

المؤلفون: Lenka Jourova, Pavel Anzenbacher, Eva Anzenbacherova

المصدر: Biomedical Papers, Vol 160, Iss 3, Pp 317-326 (2016)

مصطلحات موضوعية: microbiome, metabolism of drugs, gut microbiota, bioavailability, cytochromes p450, Medicine

Relation: https://biomed.papers.upol.cz/artkey/bio-201603-0001_Human_gut_microbiota_plays_a_role_in_the_metabolism_of_drugs.php; https://doaj.org/toc/1213-8118; https://doaj.org/toc/1804-7521; https://doaj.org/article/8f0fb0f709e048ef96750d7ce764cc0d

الاتاحة: https://doi.org/10.5507/bp.2016.039
https://doaj.org/article/8f0fb0f709e048ef96750d7ce764cc0d

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/figure/Metabolism_of_metronidazole_in_humans_/16965977

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.g001

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/figure/Expression_of_CYP_enzymes_/16965986

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.g004

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/figure/Expression_of_transcription_factors_/16965983

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.g003

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/figure/Plasma_concentrations_of_metronidazole_and_2-hydroxymetronidazole_in_murine_plasma_/16965980

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.g002

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/figure/Protein_expression_of_CYP_enzymes_/16965989

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.g005

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/figure/Enzyme_activity_of_CYP_/16965992

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.g006

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/dataset/Relative_protein_expression_western_blotting_of_selected_CYP_forms_/16965998

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.t002

المؤلفون: Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms

Relation: https://figshare.com/articles/dataset/HPLC_conditions_for_the_measurement_of_enzyme_activity_assays_/16965995

الاتاحة: https://doi.org/10.1371/journal.pone.0259643.t001