المؤلفون: Ballal, Aditya, Datta, Esha, DePaul, Gregory A., Carlsson, Erik, Chen-Izu, Ye, López, Javier E., Izu, Leighton T.

مصطلحات موضوعية: Computer Science - Machine Learning, Quantitative Biology - Quantitative Methods, Statistics - Machine Learning

URL الوصول: http://arxiv.org/abs/2501.10471

المؤلفون: Liem, David A, Silva, Hitalo, Romero, Erick, Rocha, Paulo, Acevedo, Pablo E, Izu, Miki R, Ballal, Aditya, Soroya, Mohammad, López, Javier E, Nuno, Miriam A, Quazi, Arnib, Mukherjee, Chitra, Linklater, Wayne, Ebong, Imo, Zhang, Xiao-Dong, Izu, Leighton T, Sirish, Padmini, Chiamvimonvat, Nipavan, Cadeiras, Martin

المصدر: Circulation Research. 135(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Clinical Research, Cardiovascular, Heart Disease, 2.1 Biological and endogenous factors, Humans, Heart Failure, Stroke Volume, Phenotype, Male, Female, Residence Characteristics, Aged, Middle Aged, Risk Factors, cardiovascular diseases, heart failure, social determinants of health, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences

URL الوصول: https://escholarship.org/uc/item/7gr3h694

المؤلفون: Asuka Hatano, Leighton T. Izu, Ye Chen-Izu, Daisuke Sato

المصدر: iScience, Vol 28, Iss 2, Pp 111788- (2025)

مصطلحات موضوعية: cardiovascular medicine, cell biology, bioinformatics, Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004225000471; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/420a43d9372145d18f2da3626dfacfd5

المؤلفون: Datta, Esha, Ballal, Aditya, López, Javier E, Izu, Leighton T

المصدر: PLOS Digital Health. 2(8)

مصطلحات موضوعية: Information and Computing Sciences, Biological Sciences, Biomedical and Clinical Sciences, Clinical Sciences, Precision Medicine, Networking and Information Technology R&D (NITRD), 4.2 Evaluation of markers and technologies, Generic health relevance, Good Health and Well Being

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/59q793d3
https://escholarship.org/content/qt59q793d3/qt59q793d3.pdf

المؤلفون: Chen-Izu, Ye, Hegyi, Bence, Jian, Zhong, Horvath, Balazs, Shaw, John A, Banyasz, Tamas, Izu, Leighton T

المصدر: Physiological mini-reviews. 16(3)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Heart Disease, Cardiovascular, Neurosciences, Heart Disease - Coronary Heart Disease, action potential, arrhythmia, cardiac myocyte, electrophysiology, patch-clamp

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7731v5xv

المؤلفون: Wang, Huijia, Zhu, Guangxian, Izu, Leighton T, Chen-Izu, Ye, Ono, Naoaki, Altaf-Ul-Amin, Kanaya, Shigehiko, Huang, Ming

مصطلحات موضوعية: Biochemistry and Cell Biology, Medical Physiology, Biomedical and Clinical Sciences, Biological Sciences, Networking and Information Technology R&D (NITRD), hERG, cardiotoxicity, graph transformer neural network, meta-path, dual-threshold, Physiology, Psychology, Biochemistry and cell biology, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6d9395xn
https://escholarship.org/content/qt6d9395xn/qt6d9395xn.pdf

المؤلفون: Kudo, Sota, Chen, Zheng, Zhou, Xue, Izu, Leighton T, Chen-Izu, Ye, Zhu, Xin, Tamura, Toshiyo, Kanaya, Shigehiko, Huang, Ming

مصطلحات موضوعية: Biochemistry and Cell Biology, Medical Physiology, Biomedical and Clinical Sciences, Biological Sciences, Cardiovascular, Heart Disease, atrial fibrillation, ectopic beats, normal sinus rhythm, deep learning, artificial neural network, model generalizability, Physiology, Psychology, Biochemistry and cell biology, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9rv8k6km
https://escholarship.org/content/qt9rv8k6km/qt9rv8k6km.pdf

المؤلفون: Horváth, Balázs, Szentandrássy, Norbert, Dienes, Csaba, Kovács, Zsigmond M, Nánási, Péter P, Chen-Izu, Ye, Izu, Leighton T, Banyasz, Tamas

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Neurosciences, Heart Disease, cardiac electrophysiology, voltage clamp, action potential voltage clamp, ion current, pharmacology, Physiology, Psychology, Biochemistry and cell biology, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2g77r92q
https://escholarship.org/content/qt2g77r92q/qt2g77r92q.pdf

المؤلفون: Hegyi, Bence, Shimkunas, Rafael, Jian, Zhong, Izu, Leighton T, Bers, Donald M, Chen-Izu, Ye

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(31)

مصطلحات موضوعية: Engineering, Medical Physiology, Biomedical and Clinical Sciences, Biomedical Engineering, Cardiovascular, Heart Disease, Action Potentials, Animals, Arrhythmias, Cardiac, Biomechanical Phenomena, Calcium, Calcium Signaling, Cells, Cultured, Electrophysiological Phenomena, Hydrogels, Male, Myocardial Contraction, Myocytes, Cardiac, Nitric Oxide Synthase Type I, Patch-Clamp Techniques, Rabbits, Signal Transduction, Viscoelastic Substances, mechano-chemo-transduction, cardiac arrhythmia, action potential, mechanosensitive ion channels, intracellular calcium cycling

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5fr4f7c2
https://escholarship.org/content/qt5fr4f7c2/qt5fr4f7c2.pdf

المؤلفون: Holgate, A., White, P. R., Leighton, T. G., Kemp, P. S.

المصدر: Scientific Reports ; volume 14, issue 1 ; ISSN 2045-2322

الاتاحة: https://doi.org/10.1038/s41598-024-56278-w
https://www.nature.com/articles/s41598-024-56278-w.pdf
https://www.nature.com/articles/s41598-024-56278-w

المؤلفون: Izu, Leighton T, Kohl, Peter, Boyden, Penelope A, Miura, Masahito, Banyasz, Tamas, Chiamvimonvat, Nipavan, Trayanova, Natalia, Bers, Donald M, Chen‐Izu, Ye

المصدر: The Journal of Physiology. 598(7)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Bioengineering, Arrhythmias, Cardiac, Excitation Contraction Coupling, Humans, Myocardial Contraction, Myocytes, Cardiac, Anrep effect, cardiac muscle, excitation-contraction coupling, Frank-Starling, mechano-chemo-transduction, mechano-electric coupling, myocardial contractility, Biological Sciences, Medical and Health Sciences, Physiology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2dj257vh
https://escholarship.org/content/qt2dj257vh/qt2dj257vh.pdf

المؤلفون: Hegyi, Bence, Chen-Izu, Ye, Izu, Leighton T, Rajamani, Sridharan, Belardinelli, Luiz, Bers, Donald M, Bányász, Tamás

المصدر: Circulation Arrhythmia and Electrophysiology. 13(4)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, Rare Diseases, 4.1 Discovery and preclinical testing of markers and technologies, Action Potentials, Animals, Anti-Arrhythmia Agents, Arrhythmias, Cardiac, Delayed Rectifier Potassium Channels, Disease Models, Animal, Heart Failure, Heart Rate, Kinetics, Male, Myocytes, Cardiac, Potassium, Rabbits, Sodium, Sodium Channels, Swine, Swine, Miniature, action potential, Brugada syndrome, heart, long QT syndrome, tetrodotoxin, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5jf2z029
https://escholarship.org/content/qt5jf2z029/qt5jf2z029.pdf

المؤلفون: Hegyi, Bence, Chen-Izu, Ye, Izu, Leighton T, Bányász, Tamás

المصدر: Canadian Journal of Physiology and Pharmacology. 97(8)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Heart Disease, Cardiovascular, Action Potentials, Adrenergic beta-Agonists, Animals, Heart Ventricles, Hyperkalemia, Isoproterenol, Male, Myocytes, Cardiac, Potassium, Rabbits, hyperkalemia, sympathetic stimulation, cellular electrophysiology, heart, potassium channels, action potential voltage-clamp, physical exercise, arrhythmia, arythmie, canaux potassiques, cœur, exercice physique, hyperkaliémie, stimulation sympathique, voltage-clamp du potentiel d’action, électrophysiologie cellulaire, Pharmacology and Pharmaceutical Sciences, Physiology, Medical physiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7k94m91s
https://escholarship.org/content/qt7k94m91s/qt7k94m91s.pdf

المؤلفون: Hegyi, Bence, Morotti, Stefano, Liu, Caroline, Ginsburg, Kenneth S, Bossuyt, Julie, Belardinelli, Luiz, Izu, Leighton T, Chen-Izu, Ye, Bányász, Tamás, Grandi, Eleonora, Bers, Donald M

المصدر: Circulation Arrhythmia and Electrophysiology. 12(3)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, Action Potentials, Animals, Arrhythmias, Cardiac, Calcium Channels, L-Type, Calcium Signaling, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Computer Simulation, Disease Models, Animal, Heart Failure, Heart Rate, Heart Ventricles, Male, Models, Cardiovascular, Myocytes, Cardiac, Rabbits, Risk Factors, Sodium, Time Factors, action potential, buffers, electrophysiology, heart failure, rabbits, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7dw252cn
https://escholarship.org/content/qt7dw252cn/qt7dw252cn.pdf

المؤلفون: Huijia Wang, Guangxian Zhu, Leighton T. Izu, Ye Chen-Izu, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang

مصطلحات موضوعية: Physiology, Exercise Physiology, Nutritional Physiology, Reproduction, Cell Physiology, Systems Physiology, Animal Physiology - Biophysics, Animal Physiology - Cell, Animal Physiology - Systems, Comparative Physiology, Physiology not elsewhere classified, hERG, cardiotoxicity, graph transformer neural network, meta-path, dual-threshold

Relation: https://figshare.com/articles/presentation/Presentation1_On_QSAR-based_cardiotoxicity_modeling_with_the_expressiveness-enhanced_graph_learning_model_and_dual-threshold_scheme_pdf/22786013

الاتاحة: https://doi.org/10.3389/fphys.2023.1156286.s001
https://figshare.com/articles/presentation/Presentation1_On_QSAR-based_cardiotoxicity_modeling_with_the_expressiveness-enhanced_graph_learning_model_and_dual-threshold_scheme_pdf/22786013

المؤلفون: Esha Datta, Aditya Ballal, Javier E López, Leighton T Izu

المصدر: PLOS Digital Health, Vol 2, Iss 8, p e0000307 (2023)

مصطلحات موضوعية: Computer applications to medicine. Medical informatics, R858-859.7

وصف الملف: electronic resource

Relation: https://journals.plos.org/digitalhealth/article/file?id=10.1371/journal.pdig.0000307&type=printable; https://doaj.org/toc/2767-3170

URL الوصول: https://doaj.org/article/dde01f0b08804370b5f531435a3e5df6

المؤلفون: Huijia Wang, Guangxian Zhu, Leighton T. Izu, Ye Chen-Izu, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang

المصدر: Frontiers in Physiology, Vol 14 (2023)

مصطلحات موضوعية: hERG, cardiotoxicity, graph transformer neural network, meta-path, dual-threshold, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2023.1156286/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/aaf79c6863b04ba7aa4e1681727936ec

المؤلفون: Hegyi, Bence, Bányász, Tamás, Izu, Leighton T, Belardinelli, Luiz, Bers, Donald M, Chen-Izu, Ye

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, 1.1 Normal biological development and functioning, Action Potentials, Animals, Calcium, Calcium Signaling, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cyclic AMP-Dependent Protein Kinases, Electrophysiological Phenomena, Myocytes, Cardiac, Nitric Oxide Synthase, Rabbits, Reactive Oxygen Species, Receptors, Adrenergic, beta, Sodium, Tetrodotoxin, Late sodium current, Action potential, Beta-adrenergic stimulation, Protein kinase A, Ca2+/calmodulin-dependent kinase II, Nitric oxide synthase, Ca(2+)/calmodulin-dependent kinase II, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Biochemistry and cell biology, Cardiovascular medicine and haematology, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/533093p8
https://escholarship.org/content/qt533093p8/qt533093p8.pdf

المؤلفون: Hegyi, Bence, Bossuyt, Julie, Griffiths, Leigh G, Shimkunas, Rafael, Coulibaly, Zana, Jian, Zhong, Grimsrud, Kristin N, Sondergaard, Claus S, Ginsburg, Kenneth S, Chiamvimonvat, Nipavan, Belardinelli, Luiz, Varró, András, Papp, Julius G, Pollesello, Piero, Levijoki, Jouko, Izu, Leighton T, Boyd, W Douglas, Bányász, Tamás, Bers, Donald M, Chen-Izu, Ye

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(13)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Heart Disease, Cardiovascular, Heart Disease - Coronary Heart Disease, Action Potentials, Animals, Arrhythmias, Cardiac, Calcium, Cells, Cultured, Electrophysiological Phenomena, Heart Failure, Myocardial Infarction, Myocytes, Cardiac, Swine, ischemic heart failure, myocardial infarction, electrophysiology, action potential, ionic currents

URL الوصول: https://escholarship.org/uc/item/1c67350c

المؤلفون: Zhang, Xiao-Dong, Coulibaly, Zana A, Chen, Wei Chun, Ledford, Hannah A, Lee, Jeong Han, Sirish, Padmini, Dai, Gu, Jian, Zhong, Chuang, Frank, Brust-Mascher, Ingrid, Yamoah, Ebenezer N, Chen-Izu, Ye, Izu, Leighton T, Chiamvimonvat, Nipavan

المصدر: Scientific reports. 8(1)

مصطلحات موضوعية: Cells, Cultured, Myocytes, Cardiac, Animals, Rabbits, Humans, Thapsigargin, Ryanodine, Caffeine, Calcium Channels, L-Type, Ryanodine Receptor Calcium Release Channel, Calcium Signaling, Membrane Potentials, Male, Small-Conductance Calcium-Activated Potassium Channels, HEK293 Cells, Calcium Channels, L-Type, Cells, Cultured, Myocytes, Cardiac

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0c42x239