المؤلفون: John N Snouwaert, Leigh A Jania, Trang Nguyen, David R Martinez, Alexandra Schäfer, Nicholas J Catanzaro, Kendra L Gully, Ralph S Baric, Mark Heise, Martin T Ferris, Elizabeth Anderson, Katia Pressey, Jacob A Dillard, Sharon Taft-Benz, Victoria K Baxter, Jenny P-Y Ting, Beverly H Koller

المصدر: PLoS Pathogens, Vol 19, Iss 2, p e1011168 (2023)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/75be0b479d294111a5b725cdfbedb42c

المؤلفون: Haoting Li (11668435), Anne E. Mattingly (9247975), Leigh A. Jania (6597362), Richard Smith (45265), Roberta J. Melander (1751032), Robert K. Ernst (127237), Beverley H. Koller (11668438), Christian Melander (1751038)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Developmental Biology, Cancer, Mental Health, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, resistant bacterial infections, identified several analogues, β inhibitor imd, 0354 analogues incorporating, several gram, recently disclosed, negative strains, negative bacteria, known ikk, global threat, generation library, benzimidazole moiety, benzimidazole isosteres, amide isostere

Relation: https://figshare.com/articles/journal_contribution/Benzimidazole_Isosteres_of_Salicylanilides_Are_Highly_Active_Colistin_Adjuvants/16965364

الاتاحة: https://doi.org/10.1021/acsinfecdis.1c00463.s001

المؤلفون: Kelsey A Behrens, Leigh A Jania, John N Snouwaert, MyTrang Nguyen, Sheryl S Moy, Andrey P Tikunov, Jeffrey M Macdonald, Beverly H Koller

المصدر: PLoS ONE, Vol 14, Iss 11, p e0225449 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3bfefc70a31c4aed8966846980f44286

المؤلفون: Beverly H, Koller, John N, Snouwaert, Christelle, Douillet, Leigh A, Jania, Hisham, El-Masri, David J, Thomas, Miroslav, Stýblo

المصدر: Environmental Health Perspectives

مصطلحات موضوعية: inorganic chemicals, Mice, integumentary system, Animals, Humans, Methyltransferases, Science Selection, Arsenicals, Arsenic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::84f12148974255887dea82fe737434fe
https://pubmed.ncbi.nlm.nih.gov/33054428

المؤلفون: John N. Snouwaert, Miroslav Stýblo, Beverly H. Koller, David J. Thomas, Christelle Douillet, Leigh A. Jania, Hisham A. El-Masri

المصدر: Environmental Health Perspectives. 128

مصطلحات موضوعية: inorganic chemicals, Chronic exposure, Methyltransferase, integumentary system, Inorganic arsenic, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, chemistry.chemical_element, Locus (genetics), Metabolism, Methylation, 010501 environmental sciences, Biology, Pharmacology, 01 natural sciences, 03 medical and health sciences, 0302 clinical medicine, chemistry, 030212 general & internal medicine, Arsenic, 0105 earth and related environmental sciences, Synteny

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a489b20dcbf050140f5ffc6c9fa06b40
https://doi.org/10.1289/ehp6943

المؤلفون: Beverly H. Koller, Christian Melander, Roberta J. Melander, Leigh A. Jania, William T. Barker

المصدر: Chem Biol Drug Des

مصطلحات موضوعية: Gram-negative bacteria, medicine.drug_class, Antibiotics, Drug resistance, Microbial Sensitivity Tests, 01 natural sciences, Biochemistry, Tacrolimus, Article, Microbiology, Drug Resistance, Multiple, Bacterial, Drug Discovery, Gram-Negative Bacteria, medicine, Ascomycin, Pharmacology, Flavonoids, biology, 010405 organic chemistry, Colistin, Organic Chemistry, Eukaryota, Drug Synergism, biology.organism_classification, Antimicrobial, Phosphoric Monoester Hydrolases, 0104 chemical sciences, Anti-Bacterial Agents, 010404 medicinal & biomolecular chemistry, Drug of last resort, Molecular Medicine, Bacteria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d9d82bef3234920bf6bd6e11c4ed4b
https://pubmed.ncbi.nlm.nih.gov/32562384

المؤلفون: Christian Melander, Akash Basak, Tyler A. Hendricks, Leigh A. Jania, Patrick M. O'Connor, Santiana A. Marrujo, William T. Barker, Roberta J. Melander, Beverly H. Koller, Ansley M Nemeth, Ashley E. Sullivan, Alexander W. Weig

المصدر: ChemMedChem

مصطلحات موضوعية: Acinetobacter baumannii, Gram-negative bacteria, medicine.drug_class, Klebsiella pneumoniae, Antibiotics, Microbial Sensitivity Tests, 01 natural sciences, Biochemistry, Article, Microbiology, Structure-Activity Relationship, Antibiotic resistance, Drug Resistance, Multiple, Bacterial, Drug Discovery, polycyclic compounds, Medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, Adjuvants, Pharmaceutic, Pharmacology, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, business.industry, Colistin, Organic Chemistry, Structure function, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, 0104 chemical sciences, Anti-Bacterial Agents, 010404 medicinal & biomolecular chemistry, Benzamides, Molecular Medicine, business, Bacteria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514bab61b6d0093a10fe6b352dc148ab
https://pubmed.ncbi.nlm.nih.gov/31756025

المؤلفون: Sara M Brackett, William T. Barker, Robert K. Ernst, Courtney E. Chandler, Ansley M Nemeth, Akash Basak, Beverly H. Koller, Christian Melander, Roberta J. Melander, William J. Zuercher, Leigh A. Jania

المصدر: ACS Infect Dis

مصطلحات موضوعية: 0301 basic medicine, Gram-negative bacteria, medicine.drug_class, Polymyxin, 030106 microbiology, Microbial Sensitivity Tests, Gram-Positive Bacteria, Article, Cell Line, Lipid A, 03 medical and health sciences, chemistry.chemical_compound, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, medicine, Protein Kinase Inhibitors, Adjuvants, Pharmaceutic, Sulfonamides, Natural product, biology, Kinase, Chemistry, Colistin, Eukaryota, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Potentiator, biology.organism_classification, I-kappa B Kinase, Drug Combinations, 030104 developmental biology, Infectious Diseases, Biochemistry, Benzamides, Pyrazoles, Bacteria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d295f6b49242c0c0a1a0f946e8dfb2
https://pubmed.ncbi.nlm.nih.gov/31434474

المؤلفون: Roberta J. Melander, Christian Melander, Bradley M. Minrovic, Leigh A. Jania, Veronica B Hubble, Beverly H. Koller, William T. Barker

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: medicine.drug_class, Polymyxin, medicine.medical_treatment, Antibiotics, Human pathogen, 01 natural sciences, Biochemistry, Microbiology, Antibiotic resistance, Drug Discovery, polycyclic compounds, Medicine, biology, 010405 organic chemistry, business.industry, Organic Chemistry, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, bacterial infections and mycoses, 0104 chemical sciences, Multiple drug resistance, 010404 medicinal & biomolecular chemistry, Colistin, bacteria, lipids (amino acids, peptides, and proteins), business, Adjuvant, Bacteria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dda8bfdd139e1b625ff6b1786b3cb4
https://pubmed.ncbi.nlm.nih.gov/31098007

المؤلفون: Sheryl S. Moy, MyTrang Nguyen, Beverly H. Koller, Kelsey A. Behrens, Leigh A. Jania, John N. Snouwaert, Jeffrey M. Macdonald, Andrey P. Tikunov

المصدر: PLoS ONE, Vol 14, Iss 11, p e0225449 (2019)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, Enzyme Metabolism, Endogeny, Urine, Toxicology, Pathology and Laboratory Medicine, Biochemistry, chemistry.chemical_compound, White Blood Cells, Mice, 0302 clinical medicine, Animal Cells, Immune Physiology, Medicine and Health Sciences, Enzyme Chemistry, Glutathione Transferase, chemistry.chemical_classification, education.field_of_study, Acrylamide, Multidisciplinary, biology, Chromatographic Techniques, Stomach, Glutathione, Body Fluids, Enzymes, Isoenzymes, Glutathione S-transferase, Liver, Amino Acid Specific Chromatography, 030220 oncology & carcinogenesis, Toxicity, Inactivation, Metabolic, Medicine, Female, Anatomy, Cellular Types, Research Article, Immune Cells, Science, Population, Immunology, Research and Analysis Methods, 03 medical and health sciences, Detoxification, Glutathione Chromatography, Animals, Humans, education, Blood Cells, Mutagenicity Tests, Affinity Chromatography, Biology and Life Sciences, Proteins, Cell Biology, Gastrointestinal Tract, Disease Models, Animal, 030104 developmental biology, Enzyme, chemistry, biology.protein, Enzymology, Epoxy Compounds, Digestive System, Spleen, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6243cc0daad65a3ecac909614ab293c3
https://doaj.org/article/3bfefc70a31c4aed8966846980f44286

المؤلفون: John N. Snouwaert, Beverly H. Koller, Damaris N Lorenzo, Fernando Pardo-Manuel de Villena, Rachel J. Church, Matthew L. Wheeler, Leigh A. Jania, Andrew Saintsing, Diane Armao, Piotr A. Mieczkowski, Sheryl S. Moy, My Trang Nguyen

المصدر: Cell reports. 24(5)

مصطلحات موضوعية: 0301 basic medicine, Male, BORC complex, Neuroaxonal Dystrophies, Biology, medicine.disease_cause, Axonal Transport, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Loss of Function Mutation, Lysosome, medicine, Animals, Amyotrophic lateral sclerosis, Neurons, Mutation, Mice, Inbred BALB C, Lysosome-Associated Membrane Glycoproteins, medicine.disease, Cell biology, Complementation, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Cytoplasm, Axoplasmic transport, Kinesin, Female, Lysosomes, 030217 neurology & neurosurgery, Locomotion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed3dcfab1212ac5d94457b88776e6b5
https://pubmed.ncbi.nlm.nih.gov/30185380

المؤلفون: MyTrang Nguyen, Jérôme Besse, John N. Snouwaert, Leigh A. Jania, Pierre J. Ferré, Beverly H. Koller, Barbara Akla, Pragnya Dontu

المصدر: Cancer Research. 79:503-503

مصطلحات موضوعية: Cancer Research, Tumor microenvironment, biology, Chemistry, PTGS1, Prostaglandin, Tumor initiation, Immune checkpoint, chemistry.chemical_compound, Immune system, Oncology, biology.protein, medicine, Cancer research, lipids (amino acids, peptides, and proteins), Cyclooxygenase, Prostaglandin E2, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::609d36a920af6f5c58681e5b7d589652
https://doi.org/10.1158/1538-7445.am2019-503

المؤلفون: John N. Snouwaert, Jenny P.-Y. Ting, Max Tze Han Huang, Beverly H. Koller, Zhidan Xiang, Pamela Rose Hesker, Leigh A. Jania, Stephen E. Lommatzsch, MyTrang Nguyen, Martina Kovarova

المصدر: The Journal of Immunology. 189:2006-2016

مصطلحات موضوعية: Programmed cell death, Inflammasomes, Acute Lung Injury, Immunology, Caspase 1, Apoptosis, Inflammation, Lung injury, Biology, Article, Mice, medicine, Animals, Immunology and Allergy, Adaptor Proteins, Signal Transducing, Mice, Knockout, NLRP1, Macrophages, Pyroptosis, Inflammasome, Flow Cytometry, Cell biology, medicine.symptom, Apoptosis Regulatory Proteins, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cdf1ec53a8769f9fa8f4d1a7f3ee68
https://doi.org/10.4049/jimmunol.1201065

المؤلفون: Martina Kovarova, Leigh A. Jania, MyTrang Nguyen, Julie G. Ledford, Beverly H. Koller

المصدر: Immunology and cell biology

مصطلحات موضوعية: Male, Mice, 129 Strain, Myeloid, Chemokine CXCL1, Blotting, Western, Immunology, Gene Expression, Enzyme-Linked Immunosorbent Assay, Inflammation, Biology, Dermatitis, Contact, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, Cell trafficking, medicine, Animals, Immunology and Allergy, Ear, External, Bone Marrow Transplantation, 030304 developmental biology, Mice, Knockout, Oncogene Proteins, Antigen Presentation, 0303 health sciences, integumentary system, Interleukin-6, Reverse Transcriptase Polymerase Chain Reaction, Effector, Contact hypersensitivity, Wild type, Cell Biology, Adoptive Transfer, Mice, Inbred C57BL, medicine.anatomical_structure, Female, Lymph Nodes, ONZIN, Inflammation Mediators, medicine.symptom, Haptens, Hapten, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446da1c40866ec9183566e0a8fa78566
https://doi.org/10.1038/icb.2011.107

المؤلفون: MyTrang Nguyen, Thomas M. Coffman, Carie S. Facemire, Leigh A. Jania, Hyung Suk Kim, Beverly H. Koller, William H. Beierwaltes

المصدر: American Journal of Physiology-Renal Physiology. 301:F1035-F1041

مصطلحات موضوعية: medicine.medical_specialty, DNA, Complementary, Renin secretion, Sodium-Potassium-Chloride Symporters, Physiology, medicine.medical_treatment, EP4 Receptor, Blood Pressure, Mice, Inbred Strains, Biology, Real-Time Polymerase Chain Reaction, Dinoprostone, Mice, Paracrine signalling, Furosemide, Internal medicine, Renin, Renin–angiotensin system, medicine, Animals, Telemetry, Diuretics, Receptor, Solute Carrier Family 12, Member 1, Mice, Knockout, Kidney, Articles, Stimulation, Chemical, Mice, Inbred C57BL, Endocrinology, medicine.anatomical_structure, Cyclooxygenase 2, Mice, Inbred DBA, biology.protein, RNA, lipids (amino acids, peptides, and proteins), Cyclooxygenase, Receptors, Prostaglandin E, EP4 Subtype, Prostaglandin E

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9086392abed8de6f11de63f8cf25cfe8
https://doi.org/10.1152/ajprenal.00054.2011

المؤلفون: Leigh A. Jania, Kelly D. Chason, Stephen L. Tilley, Anton M. Jetten, Xiaoyang Hua, Grace Liao, Darlene Dixon, Christopher J. Erikson, Beverly H. Koller, Maisa Jaradat, Cliona M. Stapleton, Joshua G. McCaskill

المصدر: The Journal of Immunology. 178:3208-3218

مصطلحات موضوعية: Chemokine, Receptors, Retinoic Acid, Lymphocyte, Immunology, Inflammation, Interferon-gamma, Mice, Th2 Cells, Respiratory Hypersensitivity, medicine, Animals, Immunology and Allergy, Receptor, Sensitization, Receptors, Thyroid Hormone, biology, Allergens, Nuclear Receptor Subfamily 1, Group F, Member 3, Th1 Cells, Acquired immune system, Mice, Mutant Strains, Interleukin-10, medicine.anatomical_structure, Nuclear receptor, Antibody Formation, biology.protein, medicine.symptom, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7964c4a8ff78a247c211da923712452
https://doi.org/10.4049/jimmunol.178.5.3208

المؤلفون: Leigh A. Jania, Matthew D. Woolard, Justin E. Wilson, Lucinda L. Hensley, James R. Drake, Jeffrey A. Frelinger, Thomas H. Kawula

المصدر: The Journal of Immunology. 178:2065-2074

مصطلحات موضوعية: T cell, Indomethacin, Immunology, Biology, Dinoprostone, Microbiology, Mice, Th2 Cells, Immune system, MHC class I, medicine, Animals, Immunology and Allergy, Cytotoxic T cell, Cyclooxygenase Inhibitors, Secretion, Prostaglandin E2, Francisella tularensis, Tularemia, Cell Proliferation, Mice, Knockout, Hybridomas, Macrophages, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Membrane Proteins, biology.organism_classification, Acquired immune system, Immunity, Innate, medicine.anatomical_structure, Cyclooxygenase 2, Cyclooxygenase 1, biology.protein, Interleukin-2, Interleukin-5, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535f1ac235eb2f457de5bdaf3bab8e78
https://doi.org/10.4049/jimmunol.178.4.2065

المؤلفون: Leigh A. Jania, Julie G. Ledford, John N. Snouwaert, Anne M. Latour, Virginie Bernier, Beverly H. Koller, Alex G. Therien, Amy J. Pace, Irving C. Allen, Rino Stocco

المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L1005-L1017

مصطلحات موضوعية: Lipopolysaccharides, Pulmonary and Respiratory Medicine, Ovalbumin, Physiology, Hypothalamus, Gene Expression, Locus (genetics), Disease, Biology, Retina, Receptors, G-Protein-Coupled, Bronchoconstrictor Agents, Pathogenesis, Mice, Genetic linkage, Physiology (medical), medicine, Animals, Humans, Anaphylaxis, Lung, Gene, Neuropeptide S receptor, Asthma, Mice, Inbred BALB C, Muscle, Smooth, Pneumonia, Cell Biology, medicine.disease, Mice, Mutant Strains, respiratory tract diseases, Mice, Inbred C57BL, Disease Models, Animal, Phenotype, medicine.anatomical_structure, Acute Disease, Immunology, Respiratory Mechanics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61ec348c59ec66eeb420e2da40494c1
https://doi.org/10.1152/ajplung.00174.2006

المؤلفون: Leigh A. Jania, Subhashini Chandrasekharan, Beverly H. Koller, Laurent P. Audoly, Patsy Clark, Nicholas A. Foley

المصدر: Journal of Lipid Research, Vol 46, Iss 12, Pp 2636-2648 (2005)

مصطلحات موضوعية: medicine.medical_specialty, Prostaglandin E2 receptor, Mammary gland, Context (language use), QD415-436, Biology, Biochemistry, Dinoprostone, Gene Expression Regulation, Enzymologic, Mice, Mammary Glands, Animal, Endocrinology, Pregnancy, Internal medicine, medicine, Animals, Receptors, Prostaglandin E, Involution (medicine), prostanoid, prostaglandin E2 receptors, EP2, Prostaglandin E2, Receptor, Mice, Knockout, Membrane Proteins, Cell Biology, Receptors, Prostaglandin E, EP2 Subtype, medicine.anatomical_structure, Eicosanoid, Prostaglandin-Endoperoxide Synthases, Cell culture, eicosanoid, Cyclooxygenase 1, Female, lipids (amino acids, peptides, and proteins), gene regulation, Receptors, Prostaglandin E, EP4 Subtype, metabolism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc2b8c97d39a59b2f124dd289a367be
http://www.sciencedirect.com/science/article/pii/S0022227520328510

المؤلفون: Leigh A. Jania, Rachel J. Church, Beverly H. Koller

المصدر: Journal of immunology (Baltimore, Md. : 1950). 188(8)

مصطلحات موضوعية: Male, medicine.medical_specialty, Ovalbumin, medicine.medical_treatment, Immunology, Receptors, Antigen, T-Cell, Inflammation, Dinoprostone, Article, Allergic inflammation, chemistry.chemical_compound, Mice, Immune system, Th2 Cells, Internal medicine, medicine, Hypersensitivity, Immunology and Allergy, Animals, Receptor, Lung, Cell Proliferation, Prostaglandin-E Synthases, Mice, Knockout, biology, Membrane Proteins, Lipid signaling, Intramolecular Oxidoreductases, Mice, Inbred C57BL, Endocrinology, chemistry, Cyclooxygenase 2, biology.protein, Cyclooxygenase 1, Cytokines, Arachidonic acid, lipids (amino acids, peptides, and proteins), Female, Cyclooxygenase, medicine.symptom, Prostaglandin E

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec78aec9756c306e6e7dcdbfc47fc96
https://pubmed.ncbi.nlm.nih.gov/22412193