المؤلفون: Lee E. Dunlap, David E. Olson

المصدر: ACS Omega, Vol 3, Iss 5, Pp 4968-4973 (2018)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/76f03698de1846c787a3031638ecd4ed

المؤلفون: Maxemiliano V. Vargas, Lee E. Dunlap, Chunyang Dong, Samuel J. Carter, Robert J. Tombari, Shekib A. Jami, Lindsay P. Cameron, Seona D. Patel, Joseph J. Hennessey, Hannah N. Saeger, John D. McCorvy, John A. Gray, Lin Tian, David E. Olson

المصدر: Science. 379:700-706

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4643e13479886a50ce4cc5f472a48a12
https://doi.org/10.1126/science.adf0435

المؤلفون: Robert J. Tombari, Paige C. Mundy, Kelly M. Morales, Lee E. Dunlap, David E. Olson, Pamela J. Lein

المصدر: ACS Chemical Neuroscience. 14:875-884

مصطلحات موضوعية: Physiology, Cognitive Neuroscience, Cell Biology, General Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6bc539e087506809a564d50229b1b7dc
https://doi.org/10.1021/acschemneuro.2c00642

المؤلفون: Shawn R. Campagna, Lee E. Dunlap, Ashley M. Lato, Brandon J. Kennedy, J. Jason Collier, Susan J. Burke, Carson W. Prevatte, Alexander R. Fisch, Russell T. Smith, Konstantinos D. Vogiatzis, Justin K. Kirkland

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: medicine.drug_class, medicine.medical_treatment, Organic Chemistry, Pyrazole, Pharmacology, Biochemistry, Anti-inflammatory, Steroid, chemistry.chemical_compound, Transactivation, chemistry, Drug Discovery, medicine, Beta (finance), Insulin secretion, Dexamethasone, medicine.drug, Transrepression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f551e5a9299d54be76da135066d17a
https://europepmc.org/articles/PMC8521651/

المؤلفون: Arya Azinfar, David E. Olson, Lindsay P. Cameron, Douglas Myers-Turnbull, Lee E. Dunlap, David Kokel, Ana Cristina Grodzki, Calvin Ly, Jack C. Taylor, Robert J. Tombari, Jayashri Viswanathan, Pamela J. Lein

المصدر: Journal of Medicinal Chemistry. 63:1142-1155

مصطلحات موضوعية: Hallucinogen, 0303 health sciences, Extramural, Chemistry, Neuronal Growth, Computational biology, Key features, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Drug Discovery, Molecular Medicine, Structure–activity relationship, Identification (biology), Pharmacophore, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::776f17f21f71a2a656ea30eb7e047eb6
https://doi.org/10.1021/acs.jmedchem.9b01404

المؤلفون: Carla M. Saunders, Chun-Yi Wu, Dean J. Tantillo, David E. Olson, Robert J. Tombari, Lee E. Dunlap

المصدر: ACS Chemical Biology. 14:1866-1873

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, biology, 010405 organic chemistry, Tryptophan, General Medicine, Tryptophan Metabolism, Gut flora, biology.organism_classification, 01 natural sciences, Biochemistry, Small molecule, 0104 chemical sciences, 03 medical and health sciences, Chromatographic separation, 030104 developmental biology, chemistry, Molecular Medicine, Flux (metabolism), Ex vivo, Essential amino acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aae8985810407f4f54bf210cb67b8002
https://doi.org/10.1021/acschembio.9b00548

المؤلفون: Lindsay P. Cameron, Douglas Myers-Turnbull, Jayashri Viswanathan, Oliver Fiehn, Zachary Rabow, Guoliang Zhang, David E. Olson, Bianca Yaghoobi, Zefan Q. Hurley, Brandon M. Brown, Jamie Peters, David Kokel, Maxemiliano V. Vargas, Robert J. Tombari, Lauren J. Laskowski, Matthew N. McCarroll, John D. McCorvy, Alexander J. Pell, Taohui Liu, Pamela J. Lein, Jack C. Taylor, Yi Zuo, Ju Lu, Yann Ehinger, Michelle Tjia, Heike Wulff, Emilie I. Anderson, Lee E. Dunlap, Dorit Ron

المصدر: Nature, vol 589, iss 7842
Nature

مصطلحات موضوعية: 0301 basic medicine, Male, Tabernaemontana, function-oriented synthesis, Wistar, Single step, Chemistry Techniques, Synthetic, Arrhythmias, Inbred C57BL, Mice, Substance Misuse, Alcohol Use and Health, 0302 clinical medicine, 5-HT2A, Addictive, Receptor, Serotonin, 5-HT2A, Progesterone, media_common, Sex Characteristics, Multidisciplinary, Neuronal Plasticity, Estradiol, substance use disorder, Heroin Dependence, Depression, neuropsychiatric disorder, Substance Abuse, opioid use disorder, Extinction, Antidepressive Agents, serotonin, Alcoholism, 5.1 Pharmaceuticals, Female, Mental health, addiction, Patient Safety, psychoplastogen, Pharmacophore, Development of treatments and therapeutic interventions, Cardiac, neural plasticity, medicine.drug, Receptor, Hallucinogen, Serotonin, Substance-Related Disorders, General Science & Technology, media_common.quotation_subject, Drug-Seeking Behavior, alcohol use disorder, 5-HT2A receptor, Article, Vaccine Related, 03 medical and health sciences, Operant, medicine, Humans, Animals, Swimming, Menstrual Cycle, Behavior, antidepressant, Extramural, business.industry, Animal, Addiction, Prevention, Ibogaine, Synthetic, Neurosciences, Arrhythmias, Cardiac, Chemistry Techniques, Estrogen, Brain Disorders, Rats, Behavior, Addictive, Mice, Inbred C57BL, Heroin, Disease Models, Animal, 030104 developmental biology, Good Health and Well Being, psychedelic, Drug Design, Disease Models, Hallucinogens, Psychological, Substance use, business, Drug Abuse (NIDA only), Neuroscience, Chemical design, 030217 neurology & neurosurgery, Serotonin 5-HT2 Receptor Agonists, Conditioning

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac37c443462daef2d948da379f29fb96
https://escholarship.org/uc/item/5pp1d1vm

المؤلفون: Lee E, Dunlap, Arya, Azinfar, Calvin, Ly, Lindsay P, Cameron, Jayashri, Viswanathan, Robert J, Tombari, Douglas, Myers-Turnbull, Jack C, Taylor, Ana Cristina, Grodzki, Pamela J, Lein, David, Kokel, David E, Olson

المصدر: J Med Chem

مصطلحات موضوعية: Neurons, Mice, Structure-Activity Relationship, Neuronal Plasticity, Molecular Structure, N,N-Dimethyltryptamine, Hallucinogens, Animals, Zebrafish, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::48bb91c43a4679cce725af0fa8894f3c
https://pubmed.ncbi.nlm.nih.gov/31977208

المؤلفون: Lin Tian, Chunyang Dong, In-Wook Hwang, Won Chan Oh, Lee E. Dunlap, William C. Wetsel, David E. Olson, Calvin Ly, Junqing Sun, Maxemiliano V. Vargas, Arya Azinfar

المصدر: Cell
Cell, vol 184, iss 10

مصطلحات موضوعية: Male, Protein Conformation, Drug Evaluation, Preclinical, Biosensing Techniques, Inbred C57BL, Protein Engineering, Medical and Health Sciences, Designer Drugs, Photometry, Mice, 0302 clinical medicine, serotonin receptors, Drug Discovery, 5-HT2A, Receptor, Serotonin, 5-HT2A, Receptor, 0303 health sciences, Drug discovery, Chemistry, genetically encoded indicators, Molecular Pharmacology, Biological Sciences, Preclinical, Designer drug, Mental Health, depression, Female, Identification (biology), Hallucinogen, Single administration, Serotonin, medicine.drug_class, Structural similarity, Biology, Serotonergic, Fluorescence, Article, General Biochemistry, Genetics and Molecular Biology, Small Molecule Libraries, 03 medical and health sciences, hallucinogen, medicine, Animals, Humans, 5-HT receptor, Fluorescent Dyes, 030304 developmental biology, G protein-coupled receptor, Neurosciences, Mice, Inbred C57BL, HEK293 Cells, psychedelic, Hallucinogens, Drug Evaluation, Biosensor, Neuroscience, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de27407c1bdb5f2261f4caacfded03ce
https://doi.org/10.2139/ssrn.3745934

المؤلفون: Robert J, Tombari, Carla M, Saunders, Chun-Yi, Wu, Lee E, Dunlap, Dean J, Tantillo, David E, Olson

المصدر: ACS Chem Biol

مصطلحات موضوعية: Male, Rats, Sprague-Dawley, Magnetic Resonance Spectroscopy, Tryptophan, Animals, Female, Fluorine, Proof of Concept Study, Article, Gastrointestinal Microbiome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e80b0ecda57bcd60c7b08b162f4a0d2b
https://pubmed.ncbi.nlm.nih.gov/31449387

المؤلفون: David E. Olson, Lee E. Dunlap, Anne M. Andrews

المصدر: ACS chemical neuroscience, vol 9, iss 10

مصطلحات موضوعية: Hallucinogen, History, MDMA, Subjective effects, Physiology, Cognitive Neuroscience, N-Methyl-3,4-methylenedioxyamphetamine, 4-methylenedioxyamphetamine, Ecstasy, Mescaline, Biochemistry, History, 21st Century, Article, 03 medical and health sciences, Medicinal and Biomolecular Chemistry, 0302 clinical medicine, medicine, Humans, N-Methyl-3, 4-methylenedioxymethamphetamine, Amphetamine, Lysergic acid diethylamide, Cognitive science, Cell Biology, General Medicine, History, 20th Century, 21st Century, 030227 psychiatry, empathogen, 20th Century, Good Health and Well Being, Prosocial behavior, psychedelic, Hallucinogens, entactogen, Psychology, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f6c62ef8822a8f3caf18a3bee38a7c
https://escholarship.org/uc/item/68974449

المؤلفون: Charlie J Benson, Lindsay P. Cameron, Lee E. Dunlap, David E. Olson

المصدر: ACS Chem Neurosci

مصطلحات موضوعية: Hallucinogen, Male, Physiology, medicine.drug_class, Cognitive Neuroscience, Population, Motor Activity, Dissociative, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, N,N-Dimethyltryptamine, Rats, Inbred SHR, Conditioning, Psychological, Medicine, Animals, education, education.field_of_study, Depressive Disorder, business.industry, Cell Biology, General Medicine, Extinction (psychology), Fear, Feeding Behavior, Anxiety Disorders, Antidepressive Agents, 030227 psychiatry, Disease Models, Animal, Mood, Anxiogenic, Anti-Anxiety Agents, Exploratory Behavior, Anxiety, medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug, Clinical psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c3e7eb252535a55f1a814f2731482d
https://europepmc.org/articles/PMC7196340/

المؤلفون: Lee E, Dunlap, David E, Olson

المصدر: ACS Omega

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::133aacaacd74dc7ee9058690c57e8ade
https://pubmed.ncbi.nlm.nih.gov/29876537

المؤلفون: Brandon J. Kennedy (11437584), Ashley M. Lato (11437587), Alexander R. Fisch (11437590), Susan J. Burke (11437593), Justin K. Kirkland (5125106), Carson W. Prevatte (636595), Lee E. Dunlap (5135045), Russell T. Smith (5125901), Konstantinos D. Vogiatzis (1460164), J. Jason Collier (11437596), Shawn R. Campagna (211553)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Ecology, Immunology, Developmental Biology, Chemical Sciences not elsewhere classified, great medicinal value, cultured rat 832, 13 beta cells, 1 -( 4, based gc analogues, 11ab , 11aa , inflammatory efficacy comparable, minimal transactivation activity, limited transactivation activity, gc analogue, inflammatory activity, desired activity, activity observed, widely used, term use, sars leading, organ transplantation, mediated conditions, insulin secretion

Relation: https://figshare.com/articles/journal_contribution/Potent_Anti-Inflammatory_Arylpyrazole-Based_Glucocorticoid_Receptor_Agonists_That_Do_Not_Impair_Insulin_Secretion/16624611

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00379.s001