المؤلفون: Elizabeth A McKie, Juliet L Reid, Prafull C Mistry, Stephen L DeWall, Lee Abberley, Philip D Ambery, Blas Gil-Extremera

المصدر: PLoS ONE, Vol 11, Iss 3, p e0150018 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4773233?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/7cd9668443874859afeee368213abf12

المؤلفون: Scott G Summerfield, Huaping Tang, Vilma Decman, Lee Abberley, George Gunn, Eric Yang

المصدر: Bioanalysis. 15:127-132

مصطلحات موضوعية: Medical Laboratory Technology, Clinical Biochemistry, General Medicine, General Pharmacology, Toxicology and Pharmaceutics, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3dbc32c54fbfc5304b8fa15ef8fee559
https://doi.org/10.4155/bio-2022-0180

المؤلفون: H. A. Stirnadel-Farrant, Mary Birchler, R. Schroyer, Christine J. Watson, Oriol Bestard, Neil S. Sheerin, Stephen DeWall, John D. Scott, Stephen J. Wigmore, Lee Abberley, R. Noble, Ewen M Harrison, Menna R. Clatworthy, Robert B. Kirkpatrick, Luke Devey, M. Busz, David B. Kingsmore, Katrina Stevenson, S. Andrews, K. S. Thorneloe, E. Wlodek, Alexander N.R. Weber, D. Krull

المساهمون: Kirkpatrick, R. B. [0000-0002-8671-2361], Andrews, S. [0000-0002-5407-7201], Thorneloe, K. S. [0000-0003-3640-9839], Weber, A. [0000-0001-6952-5081], Apollo - University of Cambridge Repository, Kirkpatrick, RB [0000-0002-8671-2361], Andrews, S [0000-0002-5407-7201], Thorneloe, KS [0000-0003-3640-9839], Weber, A [0000-0001-6952-5081]

المصدر: PLoS ONE, Vol 16, Iss 3, p e0247972 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE

مصطلحات موضوعية: Male, Hyperkalemia, Physiology, medicine.medical_treatment, Biopsy, 030232 urology & nephrology, Trasplantament renal, Pilot Projects, 030204 cardiovascular system & hematology, Urine, Biochemistry, Kidney transplantation, 0302 clinical medicine, Clinical endpoint, Renal Transplantation, Medicine, education.field_of_study, Multidisciplinary, Acute kidney injury, Interleukin-18, Diàlisi, Acute Kidney Injury, Middle Aged, Tissue Donors, Body Fluids, Nephrology, Female, medicine.symptom, Anatomy, Biòpsia, Research Article, Adult, medicine.medical_specialty, Science, Population, Urology, Delayed Graft Function, Surgical and Invasive Medical Procedures, Antibodies, Monoclonal, Humanized, Urinary System Procedures, 03 medical and health sciences, Medical Dialysis, Humans, Adverse effect, education, Immunohistochemistry Techniques, Dialysis, Aged, Medicine and health sciences, Transplantation, Biology and life sciences, business.industry, Proteins, Kidneys, Organ Transplantation, Renal System, medicine.disease, Kidney Transplantation, Histochemistry and Cytochemistry Techniques, Research and analysis methods, Reperfusion, Immunologic Techniques, Interferons, business, Physiological Processes

وصف الملف: application/pdf; text/xml; application/zip

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57954ffe765b43ecca9f79d4d6a549f6

المؤلفون: Lee Abberley

المصدر: Bioanalysis. 9:1139-1144

مصطلحات موضوعية: Bioanalysis, Drug Industry, Computer science, Clinical Biochemistry, Nanotechnology, 030226 pharmacology & pharmacy, 01 natural sciences, Analytical Chemistry, Outsourcing, 03 medical and health sciences, 0302 clinical medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, Drug industry, Study Monitor, Models, Statistical, business.industry, 010401 analytical chemistry, Outsourced Services, General Medicine, Hybrid approach, 0104 chemical sciences, Medical Laboratory Technology, Biological Assay, Biochemical engineering, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b00a27d406dbee554ced145ddbf3372
https://doi.org/10.4155/bio-2017-0062

المؤلفون: Chester L. Bowen, Jonathan R Kehler, Mathew Szapacs, Lee Abberley, Christopher P. Evans, Sharon L Boram

المصدر: Bioanalysis. 8:205-214

مصطلحات موضوعية: On the fly, Clinical Biochemistry, High resolution, Nanotechnology, 030226 pharmacology & pharmacy, 01 natural sciences, Mass Spectrometry, Analytical Chemistry, Small Molecule Libraries, Matrix (chemical analysis), Clinical study, 03 medical and health sciences, 0302 clinical medicine, Limit of Detection, Tandem Mass Spectrometry, Humans, Medicine, Dosing, General Pharmacology, Toxicology and Pharmaceutics, Skin, business.industry, 010401 analytical chemistry, Reproducibility of Results, General Medicine, Assay sensitivity, Healthy Volunteers, 0104 chemical sciences, Triple quadrupole mass spectrometer, Medical Laboratory Technology, Drug development, business, Blood Chemical Analysis, Chromatography, Liquid, Biomedical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea2ebcaa2102e89d2e0bddccc781297
https://doi.org/10.4155/bio.15.242

المؤلفون: Matthew Szapacs, Kristy J Fraley, John J Ulicne, Charles S Hottenstein, David Richard Citerone, Lee Abberley

المصدر: Bioanalysis. 5:1765-1774

مصطلحات موضوعية: Immunoassay, Bioanalysis, Chromatography, medicine.diagnostic_test, Computer science, Clinical Biochemistry, Reproducibility of Results, General Medicine, Reference Standards, Molecular biology, Nonhuman primate, System a, Analytical Chemistry, Automation, Macaca fascicularis, Medical Laboratory Technology, Fully automated, medicine, Animals, General Pharmacology, Toxicology and Pharmaceutics, Reference standards

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457448198bc38d57352c2273137ca5d2
https://doi.org/10.4155/bio.13.145

المؤلفون: Elizabeth McKie, Stephen DeWall, Philip D. Ambery, Prafull Mistry, Lee Abberley, Blas Gil-Extremera, Juliet Reid

المساهمون: [McKie,EA] Respiratory R&D, GlaxoSmithKline, Uxbridge, United Kingdom. [Reid,JL] Immunoinflammation Therapy Area Unit, GlaxoSmithKline, Stevenage, United Kingdom. [Mistry,PC] Clinical Statistics, GlaxoSmithKline, Stevenage, United Kingdom. [DeWall,SL] Clinical Immunology, Biopharm R&D, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America. [Abberley,L] GlaxoSmithKline, Clinical development, Cardiovascular and Metabolic Medicines Development Centre, London, United Kingdom. [Gil-Extremera,B] Department of Medicine, University Hospital San Cecilio, Granada, Spain., Support was provided by GlaxoSmithKline.

المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150018 (2016)

مصطلحات موضوعية: Male, Obesidad, Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], Pharmacology, Pathology and Laboratory Medicine, Gastroenterology, Biochemistry, law.invention, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], 0302 clinical medicine, Endocrinology, Hipoglucemiantes, Insulin, lcsh:Science, Immune Response, Anticuerpos monoclonales humanizados, Metformin, Type 2 Diabetes, Humanos, Blood, Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2 [Medical Subject Headings], Drug Therapy, Combination, medicine.medical_specialty, Endocrine Disorders, Inflammatory Diseases, Immunology, Check Tags::Male [Medical Subject Headings], Placebo, 03 medical and health sciences, Signs and Symptoms, Drug Therapy, Glucemia, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal::Antibodies, Monoclonal, Humanized [Medical Subject Headings], Diabetes Mellitus, Humans, Metformina, Aged, lcsh:R, Biology and Life Sciences, medicine.disease, Hormones, Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings], 030104 developmental biology, Farmacoterapia combinada, Check Tags::Female [Medical Subject Headings], Diabetes Mellitus, Type 2, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents [Medical Subject Headings], lcsh:Q, Biomarkers, 0301 basic medicine, Blood Glucose, Physiology, lcsh:Medicine, Type 2 diabetes, 030204 cardiovascular system & hematology, Método con una ocultación, Randomized controlled trial, law, Medicine and Health Sciences, Single-Blind Method, Multidisciplinary, Interleucina-18, Pharmaceutics, Area under the curve, Interleukin-18, Hematology, Middle Aged, Body Fluids, Treatment Outcome, Tolerability, Physiological Parameters, Chemicals and Drugs::Organic Chemicals::Amidines::Guanidines::Biguanides::Metformin [Medical Subject Headings], Female, Anatomy, medicine.drug, Research Article, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Therapy, Combination [Medical Subject Headings], Antibodies, Monoclonal, Humanized, Blood Plasma, Internal medicine, Diabetes mellitus, medicine, Diabetes Mellitus tipo II, Hypoglycemic Agents, Obesity, Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome [Medical Subject Headings], Diabetic Endocrinology, Inflammation, business.industry, Body Weight, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-18 [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Single-Blind Method [Medical Subject Headings], Pharmacodynamics, Metabolic Disorders, Resultado del tratamiento, business, Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose::Blood Glucose [Medical Subject Headings]

وصف الملف: application/pdf; application/msword; application/vnd.oasis.opendocument.text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1512142ae4f16a98ec84a3fc1bef2d
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0150018&type=printable

المؤلفون: Martin J. Gunthorpe, Lee Abberley, Neil Derek Miller, Sara Pritchard, David D. Miller, Nolwenn Lucas, Iain P. Chessell, David Grose, David John Davies, Caterina Virginio, Novella Calcinaghi, Anton D. Michel, Joanna Quinn, James N.C. Kew, Ezio Bettini, Paul Goldsmith, Matthew Crowe

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:2620-2623

مصطلحات موضوعية: Benzimidazole, Patch-Clamp Techniques, Stereochemistry, High-throughput screening, Clinical Biochemistry, Pharmaceutical Science, Receptors, N-Methyl-D-Aspartate, Biochemistry, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Potency, Receptor, Molecular Biology, Ion channel, Analgesics, Drug discovery, musculoskeletal, neural, and ocular physiology, Organic Chemistry, Antidepressive Agents, High-Throughput Screening Assays, nervous system, chemistry, Molecular Medicine, NMDA receptor, Benzimidazoles, Selectivity, psychological phenomena and processes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4793981c547cc347e94463ef14ca20b0
https://doi.org/10.1016/j.bmcl.2012.01.108

المؤلفون: Lin-Zhi Chen, Jan Welink, Ann Lévesque, Timothy V Olah, Jaap Wieling, Stephen Vinter, Natasha Savoie, Olivier Le Blaye, Susan Spitz, Jian Wang, Gustavo Mendes Lima Santos, Mark Bustard, Fabio Garofolo, Leo Kirkovsky, Stephen C. Alley, Sam Haidar, Emma Whale, Hendrik Neubert, Bärbel Witte, Omar F Laterza, Lee Abberley, Nilufer Tampal, Noriko Katori, Brad Ackermann, Julia Heinrich, Surinder Kaur, Michael Skelly, Patricia Brown-Augsburger, Nicola Hughes, Matthew Szapacs

المصدر: Bioanalysis. 7(23)

مصطلحات موضوعية: Bioanalysis, Emerging technologies, Clinical Biochemistry, Scientific excellence, Nanotechnology, General Medicine, History, 21st Century, Analytical Chemistry, Biopharmaceutics, Medical Laboratory Technology, Engineering management, White paper, Biopharmaceutical, Humans, Business, General Pharmacology, Toxicology and Pharmaceutics, Biomarkers, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ec00e0749cdb20c4237c4fc7f1729b
https://pubmed.ncbi.nlm.nih.gov/26627049

المؤلفون: Stephen DeWall, Marian Rocha Del Cura, Elizabeth McKie, Juliet Reid, Lee Abberley, Adam Taylor, Prafull Mistry, Simon McHugh, Xin Tong, Isabelle J. Pouliquen

المصدر: International journal of clinical pharmacology and therapeutics. 52(10)

مصطلحات موضوعية: Pharmacology, Adult, Male, Adolescent, business.industry, Interleukin-18, Interleukin, Middle Aged, Placebo, Antibodies, Monoclonal, Humanized, law.invention, Randomized controlled trial, Tolerability, Pharmacokinetics, law, Pharmacodynamics, Monoclonal, Medicine, Humans, Pharmacology (medical), Single-Blind Method, Obesity, business, Whole blood

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e00c9c5daadd0cfb558c61fa39cd534
https://pubmed.ncbi.nlm.nih.gov/25109413

المؤلفون: Lee Abberley, Roni J. Weaver, LingSing Chen, Charles S Hottenstein, Xun Wang, Matthew Szapacs, Xiaodong F. Liu

المصدر: Journal of Bioanalysis & Biomedicine.

مصطلحات موضوعية: Bioanalysis, Chromatography, biology, medicine.diagnostic_test, Chemistry, Pharmaceutical Science, Polyethylene glycol, Molecular biology, chemistry.chemical_compound, Biotin, Biotinylation, Reagent, Immunoassay, biology.protein, medicine, Moiety, Avidin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d554344f5cfd5dedd47d7ffb0206555f
https://doi.org/10.4172/1948-593x.1000110

المؤلفون: Jon Graham Anthony Steadman, Daryl S. Walter, Beverley Smith, Lee Abberley, David Kenneth Dean, Elena Fonfria, Tiziana Scoccitti, Anton D. Michel, Sadhana Patel, Shilina Roman, Robert Gleave, Katharine Laura Collis, Stephen J. Medhurst, Andrew P. Moses, Aude Bebius, Paul John Beswick, Andy Billinton

المصدر: Bioorganicmedicinal chemistry letters. 20(22)

مصطلحات موضوعية: Purinergic Antagonists, Chemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Administration, Oral, Biological Availability, Haplorhini, Pharmacology, Biochemistry, Bioavailability, Rats, In vivo, Drug Discovery, Molecular Medicine, Animals, Receptors, Purinergic P2X7, Receptor, Imidazolines, Molecular Biology, Biological availability, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdb4b6ee4ecb8615e490657bc2ef801
https://pubmed.ncbi.nlm.nih.gov/20934331

المؤلفون: Kim Winborn, Nicola Shuker, Benjamin R. Bellenie, Fiona McKay, Robert W. Ward, Andrew K. Takle, N. Paul King, Sharon Butler, Alessandra Gaiba, Jon Graham Anthony Steadman, Katharine Laura Collis, Jason Witherington, Rio Boatman, Tom D. Heightman, Lee Abberley, David Kenneth Dean, Alison I. Muir, Gareth J. Sanger

المصدر: Bioorganicmedicinal chemistry letters. 19(3)

مصطلحات موضوعية: Agonist, Male, medicine.medical_specialty, medicine.drug_class, Chemistry, Pharmaceutical, Clinical Biochemistry, Growth hormone secretagogue receptor, Pharmaceutical Science, Administration, Oral, Biological Availability, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Growth hormone secretagogue, Internal medicine, Drug Discovery, medicine, Animals, Sulfones, Receptor, Receptors, Ghrelin, Molecular Biology, G protein-coupled receptor, Aryl, Organic Chemistry, Ghrelin, Rats, Endocrinology, chemistry, Models, Chemical, Hormone receptor, Drug Design, Growth Hormone, Molecular Medicine, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4f34f29948982ea29b7786568744f8
https://pubmed.ncbi.nlm.nih.gov/19128969

المؤلفون: Graham Wadsworth, Jon Graham Anthony Steadman, Nicola Shuker, Lee Abberley, Michael A. Briggs, Helmut Kraus, N. Paul King, Tom D. Heightman, David Kenneth Dean, Katharine Laura Collis, Andrew K. Takle, Kim Winborn, Jason Witherington, Gareth J. Sanger, Fiona McKay, Sharon Butler, Alessandra Gaiba, Alison I. Muir

المصدر: Bioorganicmedicinal chemistry letters. 18(6)

مصطلحات موضوعية: Agonist, Male, medicine.medical_specialty, Indoles, medicine.drug_class, High-throughput screening, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biological Availability, Peptide hormone, Biochemistry, Fluorescence, Rats, Sprague-Dawley, Structure-Activity Relationship, Growth hormone secretagogue, Internal medicine, Drug Discovery, medicine, Structure–activity relationship, Animals, Receptor, Receptors, Ghrelin, Molecular Biology, Sulfonamides, Molecular Structure, Chemistry, Organic Chemistry, digestive, oral, and skin physiology, Small molecule, Rats, Endocrinology, Receptor, Serotonin, 5-HT1B, Molecular Medicine, Ghrelin, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c166c3676ce1f0ac11de92a47952ea
https://pubmed.ncbi.nlm.nih.gov/18316188

المؤلفون: Colin A. Campbell, Alan Wise, Gail Hutley, Barry Passingham, Jason Witherington, Vincent Bordas, Christopher J. Gardner, Sharon Butler, Lee Abberley, Tom D. Heightman, Alison I. Muir, Richard L. Elliott, Fiona McKay, David Kenneth Dean, Ben Powney, Gareth J. Sanger, Manuela Berlanga, Jackie S. Scott, Jill Darton, Kim Winborn, Mark J. Longley, Maite de los Frailes

المصدر: Bioorganicmedicinal chemistry letters. 17(23)

مصطلحات موضوعية: Agonist, medicine.medical_specialty, Indoles, medicine.drug_class, Clinical Biochemistry, Growth hormone secretagogue receptor, Pharmaceutical Science, Receptor agonist activity, Peptide hormone, Biochemistry, Growth hormone secretagogue, Internal medicine, Drug Discovery, medicine, Animals, Humans, Receptors, Ghrelin, Molecular Biology, Gastric emptying, Chemistry, Human Growth Hormone, Organic Chemistry, digestive, oral, and skin physiology, Biological activity, Stereoisomerism, Rats, Endocrinology, Gastric Emptying, Molecular Medicine, Ghrelin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1074c2e9c08ae992306ec4ae9b7f9ca5
https://pubmed.ncbi.nlm.nih.gov/17942309

المؤلفون: Michael D. Coleman, Daniel L. Rathbone, Lee Abberley, Peter A. Lambert, David C. Billington

المصدر: Environmental toxicology and pharmacology. 7(1)

مصطلحات موضوعية: Pharmacology, Health, Toxicology and Mutagenesis, General Medicine, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461f21051c0ad9ab544f0e944d795f68
https://pubmed.ncbi.nlm.nih.gov/21781910

المؤلفون: Robert N. Cunliffe, John Keyte, Lee Abberley, Yashwant R. Mahida, Felicity R. A. J. Rose, Weng C. Chan

المصدر: Gastroenterology. 118:A814

مصطلحات موضوعية: medicine.medical_specialty, Hepatology, Granule (cell biology), Gastroenterology, Biology, medicine.disease, Inflammatory bowel disease, Cell biology, medicine.anatomical_structure, Internal medicine, Paneth cell, medicine, Secretion, Defensin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a3bd28573b08c33d88a30b340e554537
https://doi.org/10.1016/s0016-5085(00)85398-6