المؤلفون: Putnam, AL, Safinia, N, Medvec, A, Laszkowska, M, Wray, M, Mintz, MA, Trotta, E, Szot, GL, Liu, W, Lares, A, Lee, K, Laing, A, Lechler, RI, Riley, JL, Bluestone, JA, Lombardi, G, Tang, Q

المصدر: American Journal of Transplantation. 13(11)

مصطلحات موضوعية: Organ Transplantation, Transplantation, Biotechnology, Prevention, 5.2 Cellular and gene therapies, Development of treatments and therapeutic interventions, Animals, Cell- and Tissue-Based Therapy, Flow Cytometry, Graft Rejection, Graft vs Host Disease, Humans, Immune Tolerance, Isoantigens, Lymphocyte Activation, Mice, Mice, Inbred BALB C, Skin Transplantation, T-Lymphocytes, Regulatory, Transplantation Tolerance, Cellular therapy, clinical application, regulatory T cells, tolerance induction, Medical and Health Sciences, Surgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2vh9v3tq

المؤلفون: Mohseni, YR, Saleem, A, Tung, SL, Dudreiulh, C, Lang, C, Peng, Q, Volpe, A, Adigbli, G, Cross, A, Hester, J, Farzaneh, F, Scotta, C, Lechler, RI, Issa, F, Fruhwirth, GO, Lombardi, G

Relation: https://ora.ox.ac.uk/objects/uuid:d17ea73b-1de1-443a-b4f3-fc2c390726f5; https://doi.org/10.1002/eji.202048934

الاتاحة: https://doi.org/10.1002/eji.202048934
https://ora.ox.ac.uk/objects/uuid:d17ea73b-1de1-443a-b4f3-fc2c390726f5

المؤلفون: Fanelli, G, Romano, M, Nova-Lamperti, E, Werner Sunderland, M, Nerviani, A, Scottà, C, Bombardieri, M, Quezada, SA, Sacks, SH, Noelle, RJ, Pitzalis, C, Lechler, RI, Lombardi, G, Becker, PD

المصدر: PLoS Biology , 19 (4) , Article e3001199. (2021) (In press).

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10127202/1/journal.pbio.3001199.pdf; https://discovery.ucl.ac.uk/id/eprint/10127202/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10127202/1/journal.pbio.3001199.pdf
https://discovery.ucl.ac.uk/id/eprint/10127202/

المؤلفون: Trevelin, SC, Zampetaki, A, Sawyer, G, Ivetic, A, Brewer, AC, Smyth, LA, Marelli-Berg, F, Köchl, R, Lechler, RI, Shah, AM, Lombardi, G

مصطلحات موضوعية: Cardiology, Cell migration/adhesion, Heart failure, Immunology, Immunotherapy

Relation: JCI Insight; JCI Insight. 2021;6(18):e149301. https://doi.org/10.1172/jci. insight.149301.; https://qmro.qmul.ac.uk/xmlui/handle/123456789/74298

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/74298
https://doi.org/10.1172/jci.insight.149301

المؤلفون: Fanelli, G, Romano, M, Nova-Lamperti, E, Sunderland, MW, Nerviani, A, Scotta, C, Bombardieri, M, Quezada, SA, Sacks, SH, Noelle, RJ, Pitzalis, C, Lechler, RI, Lombardi, G, Becker, PD

Relation: PLOS BIOLOGY; ARTN e3001199; https://qmro.qmul.ac.uk/xmlui/handle/123456789/92470

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92470
https://doi.org/10.1371/journal.pbio.3001199

المؤلفون: Jacob, J, Nadkarni, S, Volpe, A, Peng, Q, Tung, SL, Hannen, RF, Mohseni, YR, Scotta, C, Marelli-Berg, FM, Lechler, RI, Smyth, LA, Fruhwirth, GO, Lombardi, G

وصف الملف: 324 - 336

Relation: Molecular Therapy: Methods & Clinical Development; Jacinta Jacob, Suchita Nadkarni, Alessia Volpe, Qi Peng, Sim L. Tung, Rosalind F. Hannen, Yasmin R. Mohseni, Cristiano Scotta, Federica M. Marelli-Berg, Robert I. Lechler, Lesley A. Smyth, Gilbert O. Fruhwirth, Giovanna Lombardi, Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment, Molecular Therapy - Methods & Clinical Development, Volume 20, 2021, Pages 324-336, https://doi.org/10.1016/j.omtm.2020.12.003.; https://qmro.qmul.ac.uk/xmlui/handle/123456789/74309

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/74309
https://doi.org/10.1016/j.omtm.2020.12.003

المؤلفون: Romano, M, Sen, M, Scottà, C, Alhabbab, RY, Rico-Armada, A, Lechler, RI, Burch, M, Lombardi, G

مصطلحات موضوعية: cell therapy, heart transplant, regulatory T cells, thymus

وصف الملف: 2086 - 2092; Print-Electronic

Relation: European Journal of Immunology; ORCiD: Marco Romano orcid:0000-0001-6089-5828; ORCiD: Cristiano Scottà orcid:0000-0003-3942-5201; Romano, M. et al. (2021) 'Isolation and expansion of thymus-derived regulatory T cells for use in pediatric heart transplant patients', European Journal of Immunology, 51 (8), pp. 2086 - 2092. doi:10.1002/eji.202048949.; https://bura.brunel.ac.uk/handle/2438/29194; https://doi.org/10.1002/eji.202048949

الاتاحة: https://bura.brunel.ac.uk/handle/2438/29194
https://doi.org/10.1002/eji.202048949

المؤلفون: Harden, PN, Game, D, Sawitzki, B, Van der Net, J, Hester, J, Bushell, A, Issa, F, Brook, MO, Alzhrani, A, Schlickeiser, S, Scotta, C, Petchey, W, Blancho, G, Tang, Q, Markmann, J, Lechler, RI, Roberts, IR, Friend, P, Hilton, R, Geissler, EK, Wood, KJ, Lombardi, G

Relation: https://ora.ox.ac.uk/objects/uuid:610c6887-110b-43f6-86d9-623985ea2433; https://doi.org/10.1111/ajt.16395

الاتاحة: https://doi.org/10.1111/ajt.16395
https://ora.ox.ac.uk/objects/uuid:610c6887-110b-43f6-86d9-623985ea2433

المؤلفون: Christakoudi, S, Runglall, M, Mobillo, P, Rebollo-Mesa, I, Tsui, T-L, Nova-Lamperti, E, Taube, C, Norris, S, Kamra, Y, Hilton, R, Augustine, T, Bhandari, S, Baker, R, Berglund, D, Carr, S, Game, D, Griffi, S, Kalra, PA, Lewis, R, Mark, PB, Marks, SD, MacPhee, I, McKane, W, Mohaupt, MG, Paz-Artal, E, Kon, SP, Seron, D, Sinha, MD, Tucker, B, Viklick, O, Stahl, D, Lechler, RI, Lord, GM, Hernandez-Fuentes, MP

المصدر: 13 ; 1

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Medicine, General & Internal, Research & Experimental, General & Internal Medicine, Research & Experimental Medicine, Kidney, Transplantation, Operational Tolerance, Biomarkers, Immunosuppressive Drugs, RT-qPCR, B-CELLS, WITHDRAWAL, TRIAL, LEADS, MZB1, PCR, 1103 Clinical Sciences, 1117 Public Health and Health Services

Relation: EBioMedicine; http://hdl.handle.net/10044/1/83181

الاتاحة: http://hdl.handle.net/10044/1/83181
https://doi.org/10.1016/j.ebiom.2020.102899

المؤلفون: Sawitzki, B, Harden, PN, Reinke, P, Moreau, A, Hutchinson, JA, Game, DS, Tang, Q, Guinan, EC, Battaglia, M, Burlingham, WJ, Roberts, ISD, Streitz, M, Josien, R, Böger, CA, Scottà, C, Markmann, JF, Hester, JL, Juerchott, K, Braudeau, C, James, B, Contreras-Ruiz, L, van der Net, JB, Bergler, T, Caldara, R, Petchey, W, Edinger, M, Dupas, N, Kapinsky, M, Mutzbauer, I, Otto, NM, Öllinger, R, Hernandez-Fuentes, MP, Issa, F, Ahrens, N, Meyenberg, C, Karitzky, S, Kunzendorf, U, Knechtle, SJ, Grinyó, J, Morris, PJ, Brent, L, Bushell, A, Turka, LA, Bluestone, JA, Lechler, RI, Schlitt, HJ, Cuturi, MC, Schlickeiser, S, Friend, PJ, Miloud, T, Scheffold, A, Secchi, A, Crisalli, K, Kang, SM, Hilton, R, Banas, B, Blancho, G, Volk, HD, Lombardi, G, Wood, KJ, Geissler, EK

وصف الملف: 1627 - 1639; Print-Electronic

Relation: The Lancet; ORCiD: Cristiano Scottà orcid:0000-0003-3942-5201; Sawitzki, B. et al. (2020) 'Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials', The Lancet, 395 (10237), pp. 1627 - 1639. doi:10.1016/S0140-6736(20)30167-7.; https://bura.brunel.ac.uk/handle/2438/29198; https://doi.org/10.1016/S0140-6736(20)30167-7

الاتاحة: https://bura.brunel.ac.uk/handle/2438/29198
https://doi.org/10.1016/S0140-6736(20)30167-7

المؤلفون: Christakoudi, S, Runglall, M, Mobillo, P, Rebollo-Mesa, I, Tsui, T-L, Nova-Lamperti, E, Norris, S, Kamra, Y, Hilton, R, Bhandari, S, Baker, R, Berglund, D, Carr, S, Game, D, Griffin, S, Kalra, PA, Lewis, R, Mark, PB, Marks, SD, Macphee, I, McKane, W, Mohaupt, MG, Pararajasingam, R, Kon, SP, Serón, D, Sinha, M, Tucker, B, Viklický, O, Lechler, RI, Lord, GM, Stahl, D, Hernandez-Fuentes, MP

وصف الملف: application/pdf

Relation: https://openaccess.sgul.ac.uk/id/eprint/109681/7/GAMSTER_MCE_AcceptedManuscript.pdf; Christakoudi, S; Runglall, M; Mobillo, P; Rebollo-Mesa, I; Tsui, T-L; Nova-Lamperti, E; Norris, S; Kamra, Y; Hilton, R; Bhandari, S; et al. Christakoudi, S; Runglall, M; Mobillo, P; Rebollo-Mesa, I; Tsui, T-L; Nova-Lamperti, E; Norris, S; Kamra, Y; Hilton, R; Bhandari, S; Baker, R; Berglund, D; Carr, S; Game, D; Griffin, S; Kalra, PA; Lewis, R; Mark, PB; Marks, SD; Macphee, I; McKane, W; Mohaupt, MG; Pararajasingam, R; Kon, SP; Serón, D; Sinha, M; Tucker, B; Viklický, O; Lechler, RI; Lord, GM; Stahl, D; Hernandez-Fuentes, MP (2018) Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation. Mol Cell Endocrinol, 473. pp. 205-216. ISSN 1872-8057 https://doi.org/10.1016/j.mce.2018.01.021 SGUL Authors: MacPhee, Iain Angus MacGregor

الاتاحة: https://openaccess.sgul.ac.uk/id/eprint/109681/
https://openaccess.sgul.ac.uk/id/eprint/109681/7/GAMSTER_MCE_AcceptedManuscript.pdf

المؤلفون: Fraser, H, Safinia, N, Grageda, N, Thirkell, S, Lowe, K, Fry, LJ, Scottá, C, Hope, A, Fisher, C, Hilton, R, Game, D, Harden, P, Bushell, A, Wood, K, Lechler, RI, Lombardi, G

مصطلحات موضوعية: Tregs, GMP process, clinical trials, cell therapy, ONE study, solid organ transplantation

وصف الملف: 198 - 209; Electronic

Relation: Molecular Therapy Methods and Clinical Development; ORCiD: Cristiano Scottá orcid:0000-0003-3942-5201; Fraser, H. et al. (2018) 'A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials', Molecular Therapy Methods and Clinical Development, 8, pp. 198 - 209. doi:10.1016/j.omtm.2018.01.006.; https://bura.brunel.ac.uk/handle/2438/29206; https://doi.org/10.1016/j.omtm.2018.01.006

الاتاحة: https://bura.brunel.ac.uk/handle/2438/29206
https://doi.org/10.1016/j.omtm.2018.01.006

المؤلفون: Romano, M, Fanelli, G, Tan, N, Nova-Lamperti, E, McGregor, R, Lechler, RI, Lombardi, G, Scottà, C

مصطلحات موضوعية: regulatory T cells, immunoregulation, monocytes, alternatively activated macrophages, cell therapy

وصف الملف: 1 - 13; Electronic

Relation: Frontiers in Immunology; ORCiD: Cristiano Scottá orcid:0000-0003-3942-5201; 1625; Romano, M. et al. (2018) 'Expanded regulatory T cells induce alternatively activated monocytes with a reduced capacity to expand T helper-17 cells', Frontiers in Immunology, 9, 1625, pp. 1 - 13. doi:10.3389/fimmu.2018.01625.; https://bura.brunel.ac.uk/handle/2438/29204; https://doi.org/10.3389/fimmu.2018.01625

الاتاحة: https://bura.brunel.ac.uk/handle/2438/29204
https://doi.org/10.3389/fimmu.2018.01625

المؤلفون: Safinia, N, Grageda, N, Scottà, C, Thirkell, S, Fry, LJ, Vaikunthanathan, T, Lechler, RI, Lombardi, G

مصطلحات موضوعية: transplantation, regulatory T cells, clinical trials, good manufacturing practice, cell therapy, technical transfer

وصف الملف: 1 - 8; Electronic

Relation: Frontiers in Immunology; ORCiD: Cristiano Scottá orcid:0000-0003-3942-5201; 354; Safinia, N. et al. (2018) 'Cell therapy in organ transplantation: Our experience on the clinical translation of regulatory T cells', Frontiers in Immunology, 2018, 9, 354, pp. 1 - 8. doi:10.3389/fimmu.2018.00354.; https://bura.brunel.ac.uk/handle/2438/29205; https://doi.org/10.3389/fimmu.2018.00354

الاتاحة: https://bura.brunel.ac.uk/handle/2438/29205
https://doi.org/10.3389/fimmu.2018.00354

المؤلفون: Halim, L, Romano, M, McGregor, R, Correa, I, Pavlidis, P, Grageda, N, Hoong, S-J, Yuksel, M, Jassem, W, Hannen, RF, Ong, M, Mckinney, O, Hayee, B, Karagiannis, SN, Powell, N, Lechler, RI, Nova-Lamperti, E, Lombardi, G

المصدر: 770 ; 757

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, TRANSCRIPTION FACTOR FOXP3, COLORECTAL-CANCER, TH2 CELLS, TUMOR MICROENVIRONMENT, GASTRIC-CANCER, EXPRESSION, IMMUNITY, MEMORY, RESPONSES, SURVIVAL, T helper-like regulatory cells, chemokine receptor, immunoregulation, tumor immunity, tumor immunology, Adult, Autocrine Communication, Female, Humans, Interleukin-2, Male, Melanoma, T-Lymphocytes, Regulatory

Relation: Cell Reports; http://hdl.handle.net/10044/1/75769

الاتاحة: http://hdl.handle.net/10044/1/75769
https://doi.org/10.1016/j.celrep.2017.06.079

المؤلفون: Nova-Lamperti, E, Romano, M, Christakoudi, S, Runglall, M, McGregor, R, Mobillo, P, Kamra, Y, Tsui, T-L, Norris, S, John, S, Boardman, DA, Lechler, RI, Lombardi, G, Hernandez-Fuentes, MP, Www.GAMBITstudy.co.uk

المصدر: e17 ; e10

مصطلحات موضوعية: www.GAMBITstudy.co.uk, 11 Medical And Health Sciences, Surgery

Relation: Transplantation; http://hdl.handle.net/10044/1/52953; https://dx.doi.org/10.1097/TP.0000000000001920

الاتاحة: http://hdl.handle.net/10044/1/52953
https://doi.org/10.1097/TP.0000000000001920

المؤلفون: Jacob, J, Nadkarni, S, Volpe, A, Peng, Q, Tung, S, Hannen, R, Scotta, C, Lechler, RI, Marelli-Berg, F, Smyth, L, Lombardi, G, Fruhwirth, GO

وصف الملف: 384 - 384

Relation: https://qmro.qmul.ac.uk/xmlui/handle/123456789/74147; https://doi.org/10.1016/j.ymthe.2021.04.019

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/74147
https://doi.org/10.1016/j.ymthe.2021.04.019

المؤلفون: Rebollo-Mesa, I, Nova-Lamperti, E, Mobillo, P, Runglall, M, Christakoudi, S, Norris, S, Smallcombe, N, Kamra, Y, Hilton, R, Bhandari, S, Baker, R, Berglund, D, Carr, S, Game, D, Griffin, S, Kalra, PA, Lewis, R, Mark, PB, Marks, S, Macphee, I, McKane, W, Mohaupt, MG, Pararajasingam, R, Kon, SP, Seron, D, Sinha, MD, Tucker, B, Viklicky, O, Lechler, RI, Lord, GM, Hernandez-Fuentes, MP

المصدر: American Journal of Transplantation , 16 (12) pp. 3443-3457. (2016)

مصطلحات موضوعية: GENE-EXPRESSION, RENAL-TRANSPLANT, T-CELLS, OPERATIONAL TOLERANCE, TNF-ALPHA, B-CELLS, ALLOGRAFT, RECIPIENTS, SIGNATURE, REJECTION

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10068728/8/Rebollo-Mesa_Biomarkers%20of%20Tolerance%20in%20Kidney%20Transplantation_%20Are%20We%20Predicting%20Tolerance%20or%20Response%20to%20Immunosuppressive%20Treatment_.pdf; https://discovery.ucl.ac.uk/id/eprint/10068728/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10068728/8/Rebollo-Mesa_Biomarkers%20of%20Tolerance%20in%20Kidney%20Transplantation_%20Are%20We%20Predicting%20Tolerance%20or%20Response%20to%20Immunosuppressive%20Treatment_.pdf
https://discovery.ucl.ac.uk/id/eprint/10068728/

المؤلفون: Alhabbab, R, Blair, P, Elgueta, R, Stolarczyk, E, Marks, E, Becker, PD, Ratnasothy, K, Smyth, L, Safinia, N, Sharif-Paghaleh, E, O'Connell, S, Noelle, RJ, Lord, GM, Howard, JK, Spencer, J, Lechler, RI, Lombardi, G

مصطلحات موضوعية: Adaptive Immunity, Adoptive Transfer, Animals, Anti-Bacterial Agents, B-Lymphocytes, Cytokines, Disease Models, Animal, Gastrointestinal Microbiome, Graft Survival, Histocompatibility Antigens Class I, Immune Tolerance, Interleukin-10, Lipopolysaccharides, Lymph Nodes, Mice, Inbred BALB C, Inbred C57BL, Knockout, Skin Transplantation, Spleen, Transplantation, Homologous

Relation: Scientific Reports; http://hdl.handle.net/10044/1/41976; http://dx.doi.org/10.1038/srep11554

الاتاحة: http://hdl.handle.net/10044/1/41976
https://doi.org/10.1038/srep11554

المؤلفون: Afzali, B, Mitchell, PJ, Edozie, FC, Povoleri, GAM, Dowson, SE, Demandt, L, Walter, G, Canavan, JB, Scotta, C, Menon, B, Chana, PS, Khamri, W, Kordasti, SY, Heck, S, Grimbacher, B, Tree, T, Cope, AP, Taams, LS, Lechler, RI, John, S, Lombardi, G

المصدر: EUROPEAN JOURNAL OF IMMUNOLOGY , 43 (8) pp. 2043-2054. (2013)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Immunology, Conversion, Human, Regulatory T (Treg) cells, STAT3, Th17, HYPER-IGE SYNDROME, RHEUMATOID-ARTHRITIS, TH17 CELLS, AUTOIMMUNE-DISEASE, SYNOVIAL-FLUID, IN-VITRO, DIFFERENTIATION, TRANSPLANTATION, INFLAMMATION, SUPPRESSION

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1436480/1/eji0043-2043.pdf; https://discovery.ucl.ac.uk/id/eprint/1436480/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1436480/1/eji0043-2043.pdf
https://discovery.ucl.ac.uk/id/eprint/1436480/