المؤلفون: Neuvonen, Mikko, Hirvensalo, Päivi, Tornio, Aleksi, Rago, Brian, West, Mark, Lazzaro, Sarah, Mathialagan, Sumathy, Varma, Manthena, Cerny, Matthew A., Costales, Chester, Ramanathan, Ragu, Rodrigues, A. David, Niemi, Mikko

المساهمون: HUSLAB, Department of Clinical Pharmacology, Department of Diagnostics and Therapeutics, University of Helsinki, Helsinki University Hospital Area, INDIVIDRUG - Individualized Drug Therapy, Research Programs Unit, Medicum

مصطلحات موضوعية: ANION TRANSPORTING POLYPEPTIDE, POLYMORPHISM MARKEDLY AFFECTS, SLCO1B1 POLYMORPHISM, ENDOGENOUS BIOMARKERS, HAPLOTYPE RECONSTRUCTION, PLASMA-CONCENTRATIONS, CYNOMOLGUS MONKEYS, DRUG-INTERACTION, GENOME-WIDE, BILE-ACIDS, Pharmacy

وصف الملف: application/pdf

Relation: This study was supported by grants from the European Research Council (Grant agreement 282109), State Funding for University-level Health Research (Finland), and the Sigrid Juselius Foundation (Helsinki, Finland), and funding from Pfizer Inc (Groton, Connecticut, USA).; Neuvonen , M , Hirvensalo , P , Tornio , A , Rago , B , West , M , Lazzaro , S , Mathialagan , S , Varma , M , Cerny , M A , Costales , C , Ramanathan , R , Rodrigues , A D & Niemi , M 2021 , ' Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers ' , Clinical Pharmacology and Therapeutics , vol. 109 , no. 3 , pp. 646-657 . https://doi.org/10.1002/cpt.2053; ORCID: /0000-0001-5713-5692/work/127003692; http://hdl.handle.net/10138/353214; 5baa484e-cb9d-4086-ad52-95681cf4ea48; 000578988500001

الاتاحة: http://hdl.handle.net/10138/353214

المؤلفون: Huh, Yeamin, Plotka, Anna, Wei, Hua, Kaplan, Julia, Raha, Nancy, Towner, Justin, Purohit, Vivek S., Dowty, Martin E., Wolk, Robert, Vourvahis, Manoli, King-Ahmad, Amanda, Mathialagan, Sumathy, West, Mark A., Lazzaro, Sarah, Ryu, Sangwoo, Rodrigues, A. David

المساهمون: Pfizer

المصدر: Pharmaceutical Research ; volume 40, issue 11, page 2639-2651 ; ISSN 0724-8741 1573-904X

الاتاحة: http://dx.doi.org/10.1007/s11095-023-03564-3
https://link.springer.com/content/pdf/10.1007/s11095-023-03564-3.pdf
https://link.springer.com/article/10.1007/s11095-023-03564-3/fulltext.html

المؤلفون: Costales, Chester, Lin, Jian, Kimoto, Emi, Yamazaki, Shinji, Gosset, James R., Rodrigues, A. David, Lazzaro, Sarah, West, Mark A., West, Michael, Varma, Manthena V. S.

المساهمون: Pfizer

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 10, issue 9, page 1018-1031 ; ISSN 2163-8306 2163-8306

الاتاحة: http://dx.doi.org/10.1002/psp4.12672
https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12672
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/psp4.12672
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12672

المؤلفون: Neuvonen, Mikko, Hirvensalo, Päivi, Tornio, Aleksi, Rago, Brian, West, Mark, Lazzaro, Sarah, Mathialagan, Sumathy, Varma, Manthena, Cerny, Matthew A., Costales, Chester, Ramanathan, Ragu, Rodrigues, A. David, Niemi, Mikko

المساهمون: H2020 European Research Council, Health Research, Sigrid Juséliuksen Säätiö, Pfizer

المصدر: Clinical Pharmacology & Therapeutics ; volume 109, issue 3, page 646-657 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1002/cpt.2053
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2053
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cpt.2053
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2053

المؤلفون: Yamazaki, Shinji, Costales, Chester, Lazzaro, Sarah, Eatemadpour, Soraya, Kimoto, Emi, Varma, Manthena V.

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 8, issue 9, page 634-642 ; ISSN 2163-8306 2163-8306

الاتاحة: http://dx.doi.org/10.1002/psp4.12458
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fpsp4.12458
https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12458
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/psp4.12458
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12458

المؤلفون: Rodrigues, David, Niosi, Mark, Eng, Heather, Healy, Christopher, Lazzaro, Sarah, Yang, Qingyi, Cerny, Matthew A.

المصدر: The Journal of Clinical Pharmacology ; volume 63, issue 8, page 875-879 ; ISSN 0091-2700 1552-4604

الاتاحة: http://dx.doi.org/10.1002/jcph.2235
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.2235
https://accp1.onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.2235

المؤلفون: Lazzaro, Sarah, West, Mark A., Eatemadpour, Soraya, Feng, Bo, Varma, Manthena V.S., Rodrigues, A. David, Temesszentandrási-Ambrus, Csilla, Kovács-Hajdu, Péter, Nerada, Zsuzsanna, Gáborik, Zsuzsanna, Costales, Chester

المصدر: Journal of Pharmaceutical Sciences ; volume 112, issue 6, page 1715-1723 ; ISSN 0022-3549

الاتاحة: http://dx.doi.org/10.1016/j.xphs.2023.01.014
https://api.elsevier.com/content/article/PII:S0022354923000151?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0022354923000151?httpAccept=text/plain

المؤلفون: Boehm, Markus, Beaumont, Kevin, Jones, Rhys, Kalgutkar, Amit S., Zhang, Liying, Atkinson, Karen, Bai, Guoyun, Brown, Janice A., Eng, Heather, Goetz, Gilles H., Holder, Brian R., Khunte, Bhagyashree, Lazzaro, Sarah, Limberakis, Chris, Ryu, Sangwoo, Shapiro, Michael J., Tylaska, Laurie, Yan, Jiangli, Turner, Rushia, Leung, Siegfried S. F., Ramaseshan, Mahesh, Price, David A., Liras, Spiros, Jacobson, Matthew P., Earp, David J., Lokey, R. Scott, Mathiowetz, Alan M., Menhaji-Klotz, Elnaz

المصدر: Journal of Medicinal Chemistry ; volume 60, issue 23, page 9653-9663 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.7b01028
http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01028
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01028

المؤلفون: Amaeze, Ogochukwu, Marques, Emily S, Wei, Wei, Lazzaro, Sarah, Johnson, Nathaniel, Varma, Manthena V S, Slitt, Angela

المصدر: Curr Drug Metab ; ISSN:1875-5453 ; Volume:22 ; Issue:14

مصطلحات موضوعية: CYP enzymes, Herbal medicine, P-glycoprotein, enzyme induction, herb-drug interaction, human hepatocytes.

Relation: https://doi.org/10.2174/1389200223666211216142904; https://pubmed.ncbi.nlm.nih.gov/34915831; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694737/

الاتاحة: https://doi.org/10.2174/1389200223666211216142904
https://pubmed.ncbi.nlm.nih.gov/34915831
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694737/

المؤلفون: Bin Muhsinah, Abdullatif, Eko Nugroho, Alfarius, Li, Huifang, Lazzaro, Sarah, DaSilva, Nicholas A., Li, Dongli, Ma, Hang, Alsayari, Abdulrhman, Morita, Hiroshi, Liu, Yongqiang, Seeram, Navindra P.

المصدر: Biomedical and Pharmaceutical Sciences Faculty Publications

مصطلحات موضوعية: 19-acetoxyingols, Euphorbia saudiarabica, P-glycoprotein, Saudiarabicains, α-glucosidase inhibition

Relation: https://digitalcommons.uri.edu/bps_facpubs/344; https://doi.org/10.1016/j.tetlet.2020.152203

الاتاحة: https://digitalcommons.uri.edu/bps_facpubs/344
https://doi.org/10.1016/j.tetlet.2020.152203

المؤلفون: Young, Kymberly D., Prause, Nicole, Lazzaro, Sarah, Siegle, Greg J.

وصف الملف: application/pdf

Relation: http://d-scholarship.pitt.edu/41216/1/brainsci-10-00790-v3.pdf; Young, Kymberly D. and Prause, Nicole and Lazzaro, Sarah and Siegle, Greg J. (2020) Low Cost MR Compatible Haptic Stimulation with Application to fMRI Neurofeedback. Brain Sciences, 10 (11). p. 790. ISSN 2076-3425

الاتاحة: http://d-scholarship.pitt.edu/41216/
http://d-scholarship.pitt.edu/41216/1/brainsci-10-00790-v3.pdf
https://doi.org/10.3390/brainsci10110790

المؤلفون: Keefer, Christopher, Chang, George, Carlo, Anthony, Novak, Jonathan J., Banker, Michael, Carey, Jackie, Cianfrogna, Julie, Eng, Heather, Jagla, Caitlin, Johnson, Nathaniel, Jones, Rhys, Jordan, Samantha, Lazzaro, Sarah, Liu, JianHua, Scott Obach, R., Riccardi, Keith, Tess, David, Umland, John, Racich, Jillian, Varma, Manthena, Visswanathan, Ravi, Di, Li

المصدر: European Journal of Pharmaceutical Sciences ; volume 155, page 105541 ; ISSN 0928-0987

الاتاحة: http://dx.doi.org/10.1016/j.ejps.2020.105541
https://api.elsevier.com/content/article/PII:S0928098720303298?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0928098720303298?httpAccept=text/plain

المؤلفون: Bi, Yi-an, Mathialagan, Sumathy, Tylaska, Laurie, Lazzaro, Sarah, Costales, Chester, Kimoto, Emi, Vildhede, Anna, Hua, Wenyi, Rodrigues, David, Tremaine, Larry, Varma, Manthena V.

المصدر: Drug Metabolism and Pharmacokinetics ; volume 35, issue 1, page S55-S56 ; ISSN 1347-4367

الاتاحة: http://dx.doi.org/10.1016/j.dmpk.2020.04.111
https://api.elsevier.com/content/article/PII:S1347436720301361?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1347436720301361?httpAccept=text/plain

المؤلفون: Varma, Manthena V.S., Bi, Yi‐an, Lazzaro, Sarah, West, Mark

المصدر: Clinical Pharmacology & Therapeutics ; volume 105, issue 6, page 1295-1299 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1002/cpt.1398
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1398
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cpt.1398
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1398

المؤلفون: Aleo, Michael D., Shah, Falgun, Allen, Scott, Barton, Hugh A., Costales, Chester, Lazzaro, Sarah, Leung, Louis, Nilson, Andrea, Obach, R. Scott, Rodrigues, A. David, Will, Yvonne

المساهمون: CSP, DSRD, Science and technology investment boards, PDM

المصدر: Chemical Research in Toxicology ; volume 33, issue 1, page 223-238 ; ISSN 0893-228X 1520-5010

الاتاحة: http://dx.doi.org/10.1021/acs.chemrestox.9b00262
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.9b00262

المؤلفون: Neuvonen, Mikko, Hirvensalo, Päivi, Tornio, Aleksi, Rago, Brian, West, Mark, Lazzaro, Sarah, Mathialagan, Sumathy, Varma, Manthena, Cerny, Matthew A., Costales, Chester, Ramanathan, Ragu, Rodrigues, A. David, Niemi, Mikko

المصدر: Clinical Pharmacology & Therapeutics; Mar2021, Vol. 109 Issue 3, p646-657, 12p

مصطلحات موضوعية: ORGANIC anion transporters, LIQUID chromatography-mass spectrometry, RECEIVER operating characteristic curves, ION transport (Biology), BIOMARKERS

المؤلفون: Bi, Yi-an, Scialis, Renato J., Lazzaro, Sarah, Mathialagan, Sumathy, Kimoto, Emi, Keefer, Julie, Zhang, Hui, Vildhede, Anna M., Costales, Chester, Rodrigues, A. David, Tremaine, Larry M., Varma, Manthena V. S.

المصدر: The AAPS Journal ; volume 19, issue 3, page 787-796 ; ISSN 1550-7416

الاتاحة: http://dx.doi.org/10.1208/s12248-017-0051-2
http://link.springer.com/content/pdf/10.1208/s12248-017-0051-2.pdf
http://link.springer.com/article/10.1208/s12248-017-0051-2/fulltext.html

المؤلفون: Bi, Yi-an, Scialis, Renato J., Lazzaro, Sarah, Mathialagan, Sumathy, Kimoto, Emi, Keefer, Julie, Zhang, Hui, Vildhede, Anna M., Costales, Chester, Rodrigues, A. David, Tremaine, Larry M., Varma, Manthena V. S.

المصدر: The AAPS Journal ; volume 19, issue 3, page 882-882 ; ISSN 1550-7416

الاتاحة: https://doi.org/10.1208/s12248-017-0061-0
http://link.springer.com/content/pdf/10.1208/s12248-017-0061-0.pdf
http://link.springer.com/article/10.1208/s12248-017-0061-0/fulltext.html

المؤلفون: Aleo, Michael D., Shah, Falgun, Allen, Scott, Barton, Hugh A., Costales, Chester, Lazzaro, Sarah, Leung, Louis, Nilson, Andrea, Obach, R. Scott, Rodrigues, A. David, Will, Yvonne

المصدر: Chemical Research in Toxicology; January 2020, Vol. 33 Issue: 1 p223-238, 16p

المؤلفون: Boehm, Markus, Beaumont, Kevin, Jones, Rhys, Kalgutkar, Amit S., Zhang, Liying, Atkinson, Karen, Bai, Guoyun, Brown, Janice A., Eng, Heather, Goetz, Gilles H., Holder, Brian R., Khunte, Bhagyashree, Lazzaro, Sarah, Limberakis, Chris, Ryu, Sangwoo, Shapiro, Michael J., Tylaska, Laurie, Yan, Jiangli, Turner, Rushia, Leung, Siegfried S. F., Ramaseshan, Mahesh, Price, David A., Liras, Spiros, Jacobson, Matthew P., Earp, David J., Lokey, R. Scott, Mathiowetz, Alan M., Menhaji-Klotz, Elnaz

المصدر: Journal of Medicinal Chemistry; 20240101, Issue: Preprints