المؤلفون: Lautz, Leonie

المصدر: OpenTox Virtual Conference 2023

Relation: https://zenodo.org/communities/ota; https://doi.org/10.5281/zenodo.12738175; https://doi.org/10.5281/zenodo.12738176; oai:zenodo.org:12738176

الاتاحة: https://doi.org/10.5281/zenodo.12738176

المؤلفون: Beaudoin, Rémy, Benfenati, Emilio, Billat, Pierre‐André, Buratti, Franca Maria, Dall'Asta, Chiara, Darney, Keyvin, Galaverna, Gianni, Dellafiora, Luca, Pedroni, Lorenzo, Hoogenboom, Ron, Lautz, Leonie, Louisse, Jochem, Roncaglioni, Alessandra, Testai, Emanuela, Tebby, Cleo, Thépaut, Élisa, Vichi, Susanna, Zeman, Florence

المصدر: EFSA Supporting Publications; Dec2024, Vol. 21 Issue 12, p1-138, 138p

مصطلحات موضوعية: ANIMAL species, ANIMAL populations, DOMESTIC animals, CYTOCHROME P-450, LABORATORY animals, SYNTHETIC marijuana

المؤلفون: Noorlander, Annelies¹ MESE@efsa.europa.eu, Lautz, Leonie¹, Holleboom, Wendy Jansen¹, Mulder, Patrick P.J.¹, Stoopen, Geert¹, Punt, Ans¹

المصدر: EFSA Supporting Publications. Jul2024, Vol. 21 Issue 7, p1-89. 89p.

مصطلحات موضوعية: *FEED additives, *ESSENTIAL oils, *ANIMAL health

المؤلفون: Punt, Ans, Lautz, Leonie, Stoopen, Geert, Pinckaers, Nicole, Rijkers, Deborah, Essers, Martien, Hoogenboom, Ron

المصدر: Toxicology in Vitro 76 (2021) ; ISSN: 0887-2333

مصطلحات موضوعية: Biotransformation, Bovine liver S9, Farm animals, PCLS, Transfer

وصف الملف: application/pdf

Relation: https://edepot.wur.nl/551944

الاتاحة: https://research.wur.nl/en/publications/in-vitro-metabolism-of-lidocaine-in-subcellular-post-mitochondria
https://doi.org/10.1016/j.tiv.2021.105228

المؤلفون: Kasteel, Emma E.J., Lautz, Leonie, S., Culot, Maxime, Kramer, Nynke, I, Zwartsen, Anne

المساهمون: Institute for Risk Assessment Sciences Utrecht (IRAS), Universiteit Utrecht / Utrecht University Utrecht, Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Laboratoire de la Barrière Hémato-Encéphalique (LBHE), Université d'Artois (UA), 3R Stimulus Fund from the Animal Welfare Body Utrecht, (The Netherlands), Faculty of Veterinary Medicine (Utrecht University, the Netherlands)

المصدر: ISSN: 0887-2333.

مصطلحات موضوعية: Baclofen, Children, Microelectrode array, Physiologically-based pharmacokinetic modelling PBPK, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.TOX]Life Sciences [q-bio]/Toxicology

Relation: info:eu-repo/semantics/altIdentifier/pmid/34293430; anses-03317990; https://anses.hal.science/anses-03317990; https://anses.hal.science/anses-03317990/document; https://anses.hal.science/anses-03317990/file/Kasteel_2021.pdf; PUBMED: 34293430

الاتاحة: https://anses.hal.science/anses-03317990
https://anses.hal.science/anses-03317990/document
https://anses.hal.science/anses-03317990/file/Kasteel_2021.pdf
https://doi.org/10.1016/j.tiv.2021.105223

المؤلفون: Quignot, Nadia, Więcek, Witold, Lautz, Leonie, Dorne, Jean-Lou, Amzal, Billy

المساهمون: Certara Evidence & Access Paris, France (CE&A), Certara Evidence & Access London, UK (CE&A), Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), European Food Safety Authority (EFSA), European Food Safety Authority (EFSA) under contract CFT/EFSA/EMRISK/2012/01, Certara

المصدر: ISSN: 0378-4274.

مصطلحات موضوعية: CYP2C19, CYP2C9, Inter-individual variability, Polymorphic pathways, Risk assessment, Uncertainty factors, MESH: Algorithms, MESH: Area Under Curve, MESH: Genetic Variation, MESH: Humans, MESH: Kinetics, MESH: Phenotype, MESH: Polymorphism, Genetic, MESH: Risk Assessment, MESH: Toxicokinetics, MESH: Xenobiotics, MESH: Bayes Theorem, MESH: Computer Simulation, MESH: Cytochrome P-450 CYP2C19, MESH: Cytochrome P-450 CYP2C9, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/33232775; anses-03449853; https://anses.hal.science/anses-03449853; https://anses.hal.science/anses-03449853/document; https://anses.hal.science/anses-03449853/file/Quignot_Nadia_2021.pdf; PUBMED: 33232775

الاتاحة: https://anses.hal.science/anses-03449853
https://anses.hal.science/anses-03449853/document
https://anses.hal.science/anses-03449853/file/Quignot_Nadia_2021.pdf
https://doi.org/10.1016/j.toxlet.2020.11.016

المؤلفون: Di Consiglio, Emma, Darney, Kevin, Buratti, Franca Maria, Turco, Laura, Vichi, Susanna, Testai, Emanuela, Lautz, Léonie, Dorne, Jean-Lou

المساهمون: Istituto Superiore di Sanita Rome, Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Wageningen Univ & Res, RIKILT, Akkermaalsbos 2, NL-6708 WB Wageningen, Netherlands, Partenaires INRAE, European Food Safety Authority (EFSA), EFSA, Contract number: GP/EFSA/SCER/2015/01

المصدر: ISSN: 0378-4274 ; Toxicology Letters ; https://hal-anses.archives-ouvertes.fr/anses-03322529 ; Toxicology Letters, Elsevier, 2021, 350, pp.162-170. ⟨10.1016/j.toxlet.2021.07.005⟩ ; https://www.sciencedirect.com/science/article/pii/S0378427421001855.

مصطلحات موضوعية: variability, uncertainty factors, human pharmacokinetics, chemical risk assessment, carboxylesterase, MESH: Carboxylesterase, MESH: Carboxylic Ester Hydrolases, MESH: Protein Isoforms, MESH: Risk Assessment, MESH: Uncertainty, MESH: Environmental Exposure, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/34256091; anses-03322529; https://hal-anses.archives-ouvertes.fr/anses-03322529; https://hal-anses.archives-ouvertes.fr/anses-03322529/document; https://hal-anses.archives-ouvertes.fr/anses-03322529/file/Di%20Consiglio_2021.pdf; PUBMED: 34256091

الاتاحة: https://hal-anses.archives-ouvertes.fr/anses-03322529
https://hal-anses.archives-ouvertes.fr/anses-03322529/document
https://hal-anses.archives-ouvertes.fr/anses-03322529/file/Di%20Consiglio_2021.pdf
https://doi.org/10.1016/j.toxlet.2021.07.005

المؤلفون: Vichi, Susanna, Buratti, Franca Maria, Di Consiglio, Emma, Turco, Laura, S. Lautz, Leonie, Darney, Keyvin, Dorne, Jean-Lou Christian Michel, Testai, Emanuela

المساهمون: Istituto Superiore di Sanita Rome, Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), European Food Safety Authority (EFSA), This project was supported by the European Food Safety Authority (EFSA) under the grant agreement no. GA/EFSA/SCER/2015/01.

المصدر: ISSN: 0378-4274 ; Toxicology Letters ; https://hal-anses.archives-ouvertes.fr/anses-03319826 ; Toxicology Letters, Elsevier, 2021, ⟨10.1016/j.toxlet.2021.07.019⟩ ; https://www.sciencedirect.com/science/article/pii/S0378427421001995.

مصطلحات موضوعية: Cytochrome P450, Enzymatic activity, Genetic polymorphisms, Risk assessment, Human variability, PBK models, Protein Isoforms, Proteomics, MESH: Cytochrome P-450 Enzyme System, MESH: Databases, Genetic, MESH: Polymorphism, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/34352333; anses-03319826; https://hal-anses.archives-ouvertes.fr/anses-03319826; https://hal-anses.archives-ouvertes.fr/anses-03319826/document; https://hal-anses.archives-ouvertes.fr/anses-03319826/file/Vichi_2021.pdf; PUBMED: 34352333

الاتاحة: https://hal-anses.archives-ouvertes.fr/anses-03319826
https://hal-anses.archives-ouvertes.fr/anses-03319826/document
https://hal-anses.archives-ouvertes.fr/anses-03319826/file/Vichi_2021.pdf
https://doi.org/10.1016/j.toxlet.2021.07.019

المؤلفون: Darney, Kevin, Lautz, Leonie, Béchaux, Camille, Wiecek, Witold, Testai, Emanuela, Amzal, Billy, Dorne, Jean-Lou

المساهمون: Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Certara UK Limited, Istituto Superiore di Sanita Rome, Quinten, European Food Safety Authority (EFSA), This work was supported by the European Food Safety Authority (EFSA) under Contract numbers: OC/EFSA/SCER/2014/06 : Witold Wiecek and Billy Amzal, and GP/EFSA/SCER/2015/01 : Keyvin Darney, Leonie Lautz and Emanuela Testai. Views expressed in this paper are the authors only and do not represent the views of the European Food safety Authority.

المصدر: ISSN: 0160-4120 ; Environment International ; https://hal-anses.archives-ouvertes.fr/anses-03318285 ; Environment International, Elsevier, 2021, 156, ⟨10.1016/j.envint.2021.106760⟩ ; https://www.sciencedirect.com/science/article/pii/S0160412021003858.

مصطلحات موضوعية: Human variability, CYP2D6, Pharmacokinetics, Bayesian Inference, Meta-analysis, Risk assessment, Uncertainty factors, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/34256299; anses-03318285; https://hal-anses.archives-ouvertes.fr/anses-03318285; https://hal-anses.archives-ouvertes.fr/anses-03318285/document; https://hal-anses.archives-ouvertes.fr/anses-03318285/file/Darney_2021.pdf; PUBMED: 34256299

الاتاحة: https://hal-anses.archives-ouvertes.fr/anses-03318285
https://hal-anses.archives-ouvertes.fr/anses-03318285/document
https://hal-anses.archives-ouvertes.fr/anses-03318285/file/Darney_2021.pdf
https://doi.org/10.1016/j.envint.2021.106760

المؤلفون: Testai, Emanuela, Bechaux, Camille, Buratti, Franca M., Darney, Keyvin, Di Consiglio, Emma, Kasteel, Emma E.J., Kramer, Nynke I., Lautz, Leonie S., Santori, Nicoletta, Skaperda, Zoi‐Vasiliki, Kouretas, Dimitrios, Turco, Laura, Vichi, Susanna

المصدر: EFSA Supporting Publications ; volume 18, issue 4 ; ISSN 2397-8325 2397-8325

الاتاحة: http://dx.doi.org/10.2903/sp.efsa.2021.en-6504
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.2903/sp.efsa.2021.EN-6504
http://onlinelibrary.wiley.com/wol1/doi/10.2903/sp.efsa.2021.EN-6504/fullpdf

المؤلفون: Wang, Jiaqi, Lautz, Leonie S., Nolte, Tom M., Posthuma, Leo, Koopman, K. Remon, Leuven, Rob S.E.W., Hendriks, A. Jan

المساهمون: Interreg, European Regional Development Fund

المصدر: Journal of Environmental Management ; volume 281, page 111873 ; ISSN 0301-4797

الاتاحة: http://dx.doi.org/10.1016/j.jenvman.2020.111873
https://api.elsevier.com/content/article/PII:S0301479720317989?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301479720317989?httpAccept=text/plain

المؤلفون: Kasteel, Emma E.J., Nijmeijer, Sandra M., Darney, Keyvin, Lautz, Leonie S., Dorne, Jean Lou C.M., Kramer, Nynke I., Westerink, Remco H.S.

المساهمون: LS IRAS Tox CMT/ATX, IRAS OH Toxicology, One Health Pharma, dIRAS RA-1

مصطلحات موضوعية: Acetylcholinesterase, Human variability, In vitro toxicodynamics, Pesticides, Uncertainty factor, Toxicology, Health, Toxicology and Mutagenesis

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/410155

الاتاحة: https://dspace.library.uu.nl/handle/1874/410155

المؤلفون: Buratti, Franca, Darney, Keyvin, Vichi, Susanna, Turco, Laura, Di Consiglio, Emma, Lautz, Leonie, Béchaux, Camille, Dorne, Jean-Lou Christian Michel, Testai, Emanuela

المساهمون: Istituto Superiore di Sanita Rome, Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), European Food Safety Authority (EFSA), European Food Safety Authority (EFSA) under the grant agreement no. GA/EFSA/SCER/2015/01.

المصدر: ISSN: 0378-4274 ; Toxicology Letters ; https://hal-anses.archives-ouvertes.fr/anses-03319305 ; Toxicology Letters, Elsevier, 2020, 337, pp.78 - 90. ⟨10.1016/j.toxlet.2020.11.007⟩ ; https://www.sciencedirect.com/science/article/pii/S0378427420304641?via%3Dihub.

مصطلحات موضوعية: Tissue localizzation, Inter-individual variability, Human risk assessment, Glutathione-S-transferases, MESH: Algorithms, MESH: Animals, MESH: Glutathione Transferase / genetics, MESH: Glutathione Transferase / metabolism, MESH: Humans, MESH: Isoenzymes / genetics, MESH: Polymorphism, Genetic, MESH: Risk Assessment / methods, MESH: Tissue Distribution, MESH: Toxicokinetics, MESH: Uncertainty, MESH: Bayes Theorem, MESH: Cytosol / enzymology, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/33189831; anses-03319305; https://hal-anses.archives-ouvertes.fr/anses-03319305; https://hal-anses.archives-ouvertes.fr/anses-03319305/document; https://hal-anses.archives-ouvertes.fr/anses-03319305/file/Buratti_2021.pdf; PUBMED: 33189831

الاتاحة: https://hal-anses.archives-ouvertes.fr/anses-03319305
https://hal-anses.archives-ouvertes.fr/anses-03319305/document
https://hal-anses.archives-ouvertes.fr/anses-03319305/file/Buratti_2021.pdf
https://doi.org/10.1016/j.toxlet.2020.11.007

المؤلفون: Kasteel, Emma E. J., Nijmeijer, Sandra M., Darney, Keyvin, Lautz, Leonie S., Dorne, Jean Lou C. M., Kramer, Nynke I., Westerink, Remco H. S.

المساهمون: European Food Safety Authority, Utrecht University

المصدر: Archives of Toxicology ; volume 94, issue 12, page 4055-4065 ; ISSN 0340-5761 1432-0738

الاتاحة: http://dx.doi.org/10.1007/s00204-020-02927-8
https://link.springer.com/content/pdf/10.1007/s00204-020-02927-8.pdf
https://link.springer.com/article/10.1007/s00204-020-02927-8/fulltext.html

المؤلفون: Bossier, Han, Cortiñas‐Abrahantes, José, Darney, Keyvin, Spyropoulos, Fotis, Lautz, Leonie S, Billat, Pierre André, Beaudouin, Rémy, Zeman, Florence, Bodin, Cléo, Dorne, Jean Lou CM

المصدر: EFSA Supporting Publications ; volume 20, issue 11 ; ISSN 2397-8325 2397-8325

الاتاحة: http://dx.doi.org/10.2903/sp.efsa.2023.en-8441
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.2903/sp.efsa.2023.EN-8441
http://onlinelibrary.wiley.com/wol1/doi/10.2903/sp.efsa.2023.EN-8441/fullpdf

المؤلفون: Bossier, Han, Spyropoulos, Fotis, Darney, Keyvin, Lautz, Leonie S, Billat, Pierre André, Beaudouin, Rémy, Zeman, Florence, Bodin, Cléo, Cortiñas‐Abrahantes, José, Dorne, Jean Lou CM

المصدر: EFSA Supporting Publications ; volume 20, issue 11 ; ISSN 2397-8325 2397-8325

الاتاحة: http://dx.doi.org/10.2903/sp.efsa.2023.en-8440
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.2903/sp.efsa.2023.EN-8440
http://onlinelibrary.wiley.com/wol1/doi/10.2903/sp.efsa.2023.EN-8440/fullpdf

المؤلفون: Dorne, Jean Lou C. M., Cortiñas‐Abrahantes, José, Spyropoulos, Fotis, Darney, Keyvin, Lautz, Leonie, Louisse, Jochem, Kass, George E. N., Carnesecchi, Edoardo, Liem, A. K. Djien, Tarazona, José V., Billat, Pierre‐André, Beaudoin, Rémy, Zeman, Florence, Bodin, Cléo, Smith, Anthony, Nathanail, Alexis, Di Nicola, Matteo R., Kleiner, Juliane, Terron, Andrea, Parra‐Morte, Juan Manuel, Verloo, Didier, Robinson, Tobin

المصدر: EFSA Journal ; volume 21, issue 11 ; ISSN 1831-4732 1831-4732

الاتاحة: http://dx.doi.org/10.2903/j.efsa.2023.e211101
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.2903/j.efsa.2023.e211101
http://onlinelibrary.wiley.com/wol1/doi/10.2903/j.efsa.2023.e211101/fullpdf

المؤلفون: Bossier Han, Cortiñas Abrahantes José, Darney Keyvin, Lautz Leonie, Vergucht, Stephanie, Verbeke Tobias, Dorne Jean-Lou

المساهمون: Bodin Cleo, Brochot Céline, Marques Gonçalo, Spyropoulos, Fotis, Paini, Alicia

مصطلحات موضوعية: human health, animal health, ecological risk assessment, toxicokinetic models, toxicodynamic models, physiologically-based kinetic models, forward dosimetry, reverse dosimetry, benchmark dose modelling, dynamic energy budget models, R Shiny, statistical analysis, Bayesian theory, Monte Carlo method, animal physiology, computer techniques, pharmacokinetics, toxicokinetics, toxicology, ecotoxicology

Relation: https://doi.org/10.5281/zenodo.889583; https://zenodo.org/communities/efsa-kj; https://doi.org/10.5281/zenodo.7494935; https://doi.org/10.5281/zenodo.7494936; oai:zenodo.org:7494936

الاتاحة: https://doi.org/10.5281/zenodo.7494936

المؤلفون: dIRAS RA-1, Kasteel, Emma E.J., Lautz, Leonie S., Culot, Maxime, Kramer, Nynke I., Zwartsen, Anne

URL: https://doi.org/10.1016/j.tiv.2021.105223
http://hdl.handle.net/1874/421131
http://www.scopus.com/inward/record.url?scp=85111306040&partnerID=8YFLogxK
0887-2333
Toxicology in Vitro
76
1
12
105223

المؤلفون: LS IRAS Tox CMT/ATX, IRAS OH Toxicology, One Health Pharma, dIRAS RA-1, Kasteel, Emma E.J., Nijmeijer, Sandra M., Darney, Keyvin, Lautz, Leonie S., Dorne, Jean Lou C.M., Kramer, Nynke I., Westerink, Remco H.S.

URL: https://doi.org/10.1007/s00204-020-02927-8
http://hdl.handle.net/1874/410155
http://www.scopus.com/inward/record.url?scp=85092355870&partnerID=8YFLogxK
0340-5761
Archives of Toxicology
94
12
4055
4065