المؤلفون: Michaela Feodoroff, Piia Mikkonen, Laura Turunen, Antti Hassinen, Lauri Paasonen, Lassi Paavolainen, Swapnil Potdar, Astrid Murumägi, Olli Kallioniemi, Vilja Pietiäinen

المصدر: SLAS Discovery, Vol 28, Iss 4, Pp 138-148 (2023)

مصطلحات موضوعية: Patient-derived cancer cells, Drug sensitivity and resistance testing, 3D matrix, Drug screening, Functional precision medicine, Medicine (General), R5-920, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2472555223000254; https://doaj.org/toc/2472-5552

URL الوصول: https://doaj.org/article/bdeaf7bd18484cce910d529df5e05a9f

المؤلفون: Perumalsamy Balaji, Anbazhagan Murugadas, Lauri Paasonen, Sellathamby Shanmugaapriya, Mohammad A. Akbarsha

المصدر: AIMS Biophysics, Vol 9, Iss 3, Pp 221-234 (2022)

مصطلحات موضوعية: 3d culture, multicellular tumor spheroids, growdex®, hydrogel, heterotypic spheroids, Biology (General), QH301-705.5, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2377-9098

URL الوصول: https://doaj.org/article/59a597ee0a50446c993c34f89b8fa548

المؤلفون: Sheetal Patpatia, Eric Schaedig, Anna Dirks, Lauri Paasonen, Mikael Skurnik, Saija Kiljunen

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

مصطلحات موضوعية: bacteriophage, phagogram, phage therapy, hydrogel, rapid test, diagnostics, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.1032052/full; https://doaj.org/toc/2235-2988

URL الوصول: https://doaj.org/article/fcd7d13b93314676b634b5a8639fa4bb

المؤلفون: Rami Mäkelä, Antti Arjonen, Ville Härmä, Nina Rintanen, Lauri Paasonen, Tobias Paprotka, Kerstin Rönsch, Teijo Kuopio, Juha Kononen, Juha K. Rantala

المصدر: BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Ex vivo drug screening, Urachal carcinoma, Rare cancer, Precision medicine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-020-07092-w; https://doaj.org/toc/1471-2407

URL الوصول: https://doaj.org/article/57759f08eeff444d9a1a852ab997f3b4

المؤلفون: Elle Koivunotko (11371385), Arto Merivaara (7420151), Akseli Niemelä (11371388), Sami Valkonen (11371391), Kalle Manninen (11371394), Henrik Mäkinen (11371397), Mira Viljanen (7295750), Kirsi Svedström (2117176), Ana Diaz (259632), Mirko Holler (1355967), Jacopo Zini (11371400), Lauri Paasonen (1269639), Ossi Korhonen (1782988), Simo Huotari (1538788), Artturi Koivuniemi (188184), Marjo Yliperttula (148514)

مصطلحات موضوعية: Medicine, Biotechnology, Evolutionary Biology, Ecology, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, molecular level interactions, obtained experimental data, future pharmaceutical applications, molecular dynamics simulations, dried nfc hydrogel, obtained successful freeze, molecular insights, simulations together, pharmaceutical site, nfc hydrogel, experimental measurements, successful freeze, wider understanding, vast amount, used lyoprotectants, term storing, suitable lyoprotectants, successful reconstitution, since freeze, sensitive pharmaceuticals, room temperature, recent years, protective matrix

Relation: https://figshare.com/articles/journal_contribution/Molecular_Insights_on_Successful_Reconstitution_of_Freeze-Dried_Nanofibrillated_Cellulose_Hydrogel/16553546

الاتاحة: https://doi.org/10.1021/acsabm.1c00739.s001

المؤلفون: Sheetal Patpatia, Eric Schaedig, Anna Dirks, Lauri Paasonen, Mikael Skurnik, Saija Kiljunen

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, bacteriophage, phagogram, phage therapy, hydrogel, rapid test, diagnostics, phage susceptibility, personalized medicine

Relation: https://figshare.com/articles/dataset/DataSheet_1_Rapid_hydrogel-based_phage_susceptibility_test_for_pathogenic_bacteria_docx/21686906

الاتاحة: https://doi.org/10.3389/fcimb.2022.1032052.s001
https://figshare.com/articles/dataset/DataSheet_1_Rapid_hydrogel-based_phage_susceptibility_test_for_pathogenic_bacteria_docx/21686906

المؤلفون: Georg Singer, Iris Zalaudek, Marjo Yliperttula, Raili Koivuniemi, Bernadette Liegl-Atzwanger, Silke Schrom, Alexander Stallinger, Florian Kleinegger, Johannes Haybaeck, Johanna Niklander, Lauri Paasonen, Beate Rinner, Gord von Campe

مصطلحات موضوعية: 0303 health sciences, Matrigel, Pathology, medicine.medical_specialty, medicine.diagnostic_test, Human skin, Vimentin, Biology, Nestin, 3. Good health, 03 medical and health sciences, Foreskin, Tissue culture, 0302 clinical medicine, medicine.anatomical_structure, In vivo, Biopsy, medicine, biology.protein, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb97c67ec2faceb2e436a625fa5f5e2c
https://doi.org/10.1101/2021.11.22.466872

المؤلفون: Henrik Makinen, Lauri Paasonen, Mirko Holler, Akseli Niemelä, Kalle Manninen, Ossi Korhonen, Marjo Yliperttula, Arto Merivaara, Artturi Koivuniemi, Kirsi Svedström, Simo Huotari, Sami Valkonen, Mira Viljanen, Ana Diaz, Elle Koivunotko, Jacopo Zini

المساهمون: Division of Pharmaceutical Biosciences, Biopharmaceutics Group, Department of Physics, Materials Physics, University Management, Helsinki In Vivo Animal Imaging Platform (HAIP), Pharmaceutical biophysics group, Doctoral Programme in Drug Research, Drug Research Program

مصطلحات موضوعية: Sucrose, Biomedical Engineering, Biocompatible Materials, nanofibrillated cellulose hydrogel, TRANSITIONS, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, 114 Physical sciences, Biomaterials, chemistry.chemical_compound, Freeze-drying, Rheology, Cellulose, trehalose, Residual water content, Biochemistry (medical), Water, Hydrogels, sucrose, General Chemistry, molecular dynamics simulations, 021001 nanoscience & nanotechnology, Trehalose, NMR, 0104 chemical sciences, ptychographic X-ray computed tomography, Freeze Drying, chemistry, Chemical engineering, freeze-drying, rheology, residual water content, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593143bf01efe063ee0411f0e6e26808
http://hdl.handle.net/10138/335295

المؤلفون: Bhumika, Singh, Mohamed Essameldin, Abdelgawad, Zulfiqur, Ali, Jarrod, Bailey, Elisa, Budyn, Prospero, Civita, Martin J D, Clift, John T, Connelly, Samuel, Constant, Marius, Hittinger, Helena, Kandarova, Victoria Rosalind, Kearns, Tony, Kiuru, Tomasz, Kostrzewski, Sebastian, Kress, Victoria Marsh, Durban, Claus-Michael, Lehr, Hayley, McMillan, Julia Katharina, Metz, Vivian, Monteban, Dania, Movia, Catia, Neto, Carla, Owen, Lauri, Paasonen, Kerri Anne, Palmer, Geoffrey John, Pilkington, Karen, Pilkington, Adriele, Prina-Mello, Clive, Roper, Jonathan, Sheard, Sheree, Smith, Janette Ellen, Turner, Ipsita, Roy, Melissa Anne, Tutty, Eirini, Velliou, John Malcolm, Wilkinson

المصدر: Alternatives to laboratory animals : ATLA. 49(3)

مصطلحات موضوعية: Lab-On-A-Chip Devices, Models, Animal, Animals, Humans, Coculture Techniques, Skin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::18333ba90fd4ecdb62c6bab88e1d8aa6
https://pubmed.ncbi.nlm.nih.gov/34225465

المؤلفون: Prospero Civita, Hayley McMillan, Catia Neto, Sheree Smith, Vivian Monteban, Lauri Paasonen, Victoria Kearns, Bhumika Singh, Kerri Palmer, Mohamed Essameldin Abdelgawad, Julia Katharina Metz, Martin J. D. Clift, Samuel Constant, Jarrod Bailey, Claus-Michael Lehr, Ipsita Roy, Adriele Prina-Mello, Karen Pilkington, Geoffrey J. Pilkington, Dania Movia, Melissa Anne Tutty, Tony Kiuru, Elisa Budyn, Zulfiqur Ali, John Malcolm Wilkinson, Tomasz Kostrzewski, Victoria Marsh Durban, Carla Owen, Jonathan Sheard, Helena Kandarova, Clive Roper, Eirini Velliou, John T. Connelly, Janette Ellen Turner, Marius Hittinger, Sebastian Kress

المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.

المصدر: Alternatives to laboratory animals : ATLA
England
ATLA-ALTERNATIVES TO LABORATORY ANIMALS
ATLA Alternatives to Laboratory Animals

مصطلحات موضوعية: 0301 basic medicine, animal replacement, media_common.quotation_subject, organoid, Toxicology, Organ-on-a-chip, General Biochemistry, Genetics and Molecular Biology, Session (web analytics), 3Rs, 03 medical and health sciences, 0302 clinical medicine, Promotion (rank), microphysiological system, media_common, organ-on-a-chip, Animal Welfare (journal), animal-free, 3-D, in vitro, General Medicine, Human physiology, tissue microenvironment, Three Rs, Variety (cybernetics), Medical Laboratory Technology, 030104 developmental biology, 030220 oncology & carcinogenesis, Engineering ethics, new approach methodologies, Psychology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8988ab9c4803495a5cb1c9d4864c2090
https://cronfa.swan.ac.uk/Record/cronfa57289/Download/57289__20529__872b5658a37a4c01a75e6229a0ad1494.pdf

المؤلفون: Ville Härmä, Nina Rintanen, Tobias Paprotka, Lauri Paasonen, Antti Arjonen, Kerstin Rönsch, Teijo Kuopio, Rami Mäkelä, Juha Rantala, Juha Kononen

المصدر: BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Urachus, Efficacy, 3D cell culture, 0302 clinical medicine, Medicine, Precision Medicine, media_common, Ex vivo drug screening, TOR Serine-Threonine Kinases, Proto-Oncogene Proteins c-met, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, 030220 oncology & carcinogenesis, Urachal carcinoma, Research Article, Drug, Adult, Urachal cancer, Cell Survival, media_common.quotation_subject, Primary Cell Culture, Context (language use), Antineoplastic Agents, Adenocarcinoma, Cystectomy, lcsh:RC254-282, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Cell Line, Tumor, Genetics, Humans, Viability assay, Cell Proliferation, Enzyme Assays, Mitogen-Activated Protein Kinase Kinases, Dose-Response Relationship, Drug, business.industry, Reproducibility of Results, Rare cancer, medicine.disease, 030104 developmental biology, Urinary Bladder Neoplasms, Mutation, Cancer research, Feasibility Studies, Drug Screening Assays, Antitumor, business, Cytometry, Ex vivo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7cfc00c01ef085be77a353bc8bfbd0
https://pubmed.ncbi.nlm.nih.gov/32576176

المؤلفون: Olli Kallioniemi, Piia Mikkonen, Lassi Paavolainen, Laura Turunen, Lauri Paasonen, Astrid Murumägi, Swapnil Potdar, Vilja Pietiäinen

المصدر: Cancer Research. 78:5029-5029

مصطلحات موضوعية: Drug, 0303 health sciences, Cancer Research, Tumor microenvironment, Matrigel, business.industry, media_common.quotation_subject, Cancer, medicine.disease, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer cell, medicine, Cancer research, Viability assay, Stem cell, Ovarian cancer, business, 030304 developmental biology, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f579770dd20caf2698cdf41f2373ef4
https://doi.org/10.1158/1538-7445.am2018-5029

المؤلفون: Michael Rappolt, Arto Urtti, Marjo Yliperttula, Lauri Paasonen, Anan Yaghmur

المصدر: The Journal of Physical Chemistry Letters. 1:962-966

مصطلحات موضوعية: Chromatography, Membrane permeability, Chemistry, Small-angle X-ray scattering, Vesicle, Phospholipid, Nanoparticle, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Colloidal gold, Phase (matter), Biophysics, General Materials Science, Lamellar structure, Physical and Theoretical Chemistry, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::07c050cf0018470756c007e304ae4f4b
https://doi.org/10.1021/jz100226v

المؤلفون: Lauri Paasonen, Erkki Ruoslahti, Thomas D.Y. Chung, Gary B. Braun, Marjo Yliperttula, Shweta Sharma, Venkata Ramana Kotamraju, Zhi-Gang She, Tambet Teesalu, Kazuki N. Sugahara, Maurizio Pellecchia, Bainan Wu

المصدر: Chembiochem : a European journal of chemical biology, vol 17, iss 7

مصطلحات موضوعية: 0301 basic medicine, Cell, Aminopyridines, Peptide, 02 engineering and technology, Pharmacology, Ligands, Biochemistry, Chemical library, law.invention, chemistry.chemical_compound, Mice, Drug Delivery Systems, law, Nanotechnology, Receptor, chemistry.chemical_classification, Cyclic, Tumor, Chemistry, 021001 nanoscience & nanotechnology, Ethylenediamines, 3. Good health, medicine.anatomical_structure, 5.1 Pharmaceuticals, Drug delivery, Recombinant DNA, Molecular Medicine, Female, Development of treatments and therapeutic interventions, 0210 nano-technology, Biotechnology, High-throughput screening, Bioengineering, Antineoplastic Agents, Breast Neoplasms, high-throughput screening, Peptides, Cyclic, Article, Cell Line, Mitochondrial Proteins, Medicinal and Biomolecular Chemistry, 03 medical and health sciences, In vivo, Cell Line, Tumor, medicine, cancer, Animals, Humans, Molecular Biology, Organic Chemistry, body regions, 030104 developmental biology, drug delivery, peptides, Nanoparticles, Biochemistry and Cell Biology, Carrier Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c5dcda883b9e602af8f20624c2cdec
https://europepmc.org/articles/PMC5433940/

المؤلفون: Lauri Paasonen, Wim E. Hennink, Arto Urtti, Birgit Romberg, Gert Storm, Marjo Yliperttula

المصدر: Bioconjugate Chemistry. 18:2131-2136

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Biomedical Engineering, Pharmaceutical Science, Bioengineering, 02 engineering and technology, 010402 general chemistry, Sensitivity and Specificity, 01 natural sciences, chemistry.chemical_compound, Polymethacrylic Acids, Dynamic light scattering, Methacrylamide, N-(2-Hydroxypropyl) methacrylamide, Pharmacology, chemistry.chemical_classification, Acrylamides, Cloud point, Liposome, Chromatography, Molecular Structure, Bilayer, Organic Chemistry, Temperature, Polymer, Fluoresceins, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Calcein, Cholesterol, chemistry, Liposomes, Lactates, 0210 nano-technology, Biotechnology, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a301f1debf78b29f4c96eff2ac7e5c4e
https://doi.org/10.1021/bc700245p

المؤلفون: Kyösti Kontturi, Timo Laaksonen, Christoffer Johans, Lauri Paasonen, Marjo Yliperttula, Arto Urtti

المصدر: Journal of Controlled Release. 122:86-93

مصطلحات موضوعية: 1,2-Dipalmitoylphosphatidylcholine, Photochemistry, Ultraviolet Rays, Lipid Bilayers, Metal Nanoparticles, Pharmaceutical Science, Nanoparticle, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Drug Delivery Systems, Microparticle, Lipid bilayer, Fluorescent Dyes, Liposome, Chemistry, Temperature, Fluoresceins, 021001 nanoscience & nanotechnology, Fluorescence, 0104 chemical sciences, Kinetics, Colloidal gold, Liposomes, Drug delivery, Phosphatidylcholines, Biophysics, Gold, 0210 nano-technology, Drug carrier, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235ab25a4df38cb52921d0de8a959347
https://doi.org/10.1016/j.jconrel.2007.06.009

المؤلفون: Arto Urtti, Marjo Yliperttula, Lauri Paasonen, Maarit Jaana Korhonen

المصدر: International Journal of Pharmaceutics. 307:188-193

مصطلحات موضوعية: Keratinocytes, Time Factors, Skin Absorption, Cell Culture Techniques, Pharmaceutical Science, Gene delivery, Biology, Transfection, Permeability, Cell Line, Fatty Acids, Monounsaturated, Gene product, Tissue culture, Stratum corneum, medicine, Animals, integumentary system, Phosphatidylethanolamines, Genetic transfer, Gene Transfer Techniques, DNA, Alkaline Phosphatase, Molecular biology, Rats, Quaternary Ammonium Compounds, medicine.anatomical_structure, Cell culture, Naked DNA, Liposomes, Feasibility Studies, Epidermis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f2939340bea3bb88448ac38c1224f3
https://doi.org/10.1016/j.ijpharm.2005.09.032

المؤلفون: Sarah J. Butcher, Marjo Yliperttula, Astrid Subrizi, Pasi Laurinmäki, Anan Yaghmur, Arto Urtti, Tuomas Sipilä, Lauri Paasonen, Michael Rappolt

المصدر: Journal of controlled release : official journal of the Controlled Release Society. 147(1)

مصطلحات موضوعية: 1,2-Dipalmitoylphosphatidylcholine, Light, Cell Survival, Lipid Bilayers, Cell Culture Techniques, Pharmaceutical Science, Metal Nanoparticles, Nanotechnology, 02 engineering and technology, Retinal Pigment Epithelium, 010402 general chemistry, 01 natural sciences, Phase Transition, Cell Line, chemistry.chemical_compound, Dogs, Drug Delivery Systems, X-Ray Diffraction, Scattering, Small Angle, Animals, Humans, Lipid bilayer phase behavior, Lipid bilayer, Liposome, Microscopy, Confocal, Chemistry, 021001 nanoscience & nanotechnology, Photochemical Processes, 0104 chemical sciences, Calcein, Kidney Tubules, Solubility, Colloidal gold, Dipalmitoylphosphatidylcholine, Drug delivery, Liposomes, Biophysics, Phosphatidylcholines, Gold, 0210 nano-technology, Drug carrier, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2654f28877e987d0b71d8f500cdc7ed9
https://pubmed.ncbi.nlm.nih.gov/20624434