المؤلفون: Willem P. J. Cox, Noël M. M. Dautzenberg, Linde Dekker, Tesa Klenovsek, Annelisa M. Cornel, Marliek van Hoesel, Dorette S. van Ingen Schenau, Reno S. Bladergroen, Roland P. Kuiper, Laurens T. van der Meer, Friso G. Calkoen, Stefan Nierkens, Frank N. van Leeuwen

المصدر: Blood Neoplasia, Vol 2, Iss 1, Pp 100060- (2025)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950328024000608; https://doaj.org/toc/2950-3280

URL الوصول: https://doaj.org/article/da35c4159a6d46e1b63aa908ed102cf8

المؤلفون: Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

المصدر: Haematologica, Vol 999, Iss 1 (2024)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/11635; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/70f5749bff5943bb9814e9df3159f0f2

المؤلفون: Willem P.J. Cox, Nils Evander, Dorette S. van Ingen Schenau, Gawin R. Stoll, Nadia Anderson, Lieke de Groot, Kari J.T. Grünewald, Rico Hagelaar, Miriam Butler, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

المصدر: Haematologica, Vol 109, Iss 6 (2023)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/11383; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/986ac4b3aae24d9999fc92fcd6366f17

المؤلفون: Miriam Butler, Britt M.T. Vervoort, Dorette S. van Ingen Schenau, Lieneke Jongeneel, Jordy C.G. van der Zwet, René Marke, Jules P.P. Meijerink, Blanca Scheijen, Laurens T. van der Meer, Frank N. van Leeuwen

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: leukemia, glucocorticoids, IKZF1, therapy resistance, AKT, ERK, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.905665/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/bd62010cd4ac4cb38d96197bfa9e66ae

المؤلفون: Blanca Scheijen, Judith M. Boer, René Marke, Esther Tijchon, Dorette van Ingen Schenau, Esmé Waanders, Liesbeth van Emst, Laurens T. van der Meer, Rob Pieters, Gabriele Escherich, Martin A. Horstmann, Edwin Sonneveld, Nicola Venn, Rosemary Sutton, Luciano Dalla-Pozza, Roland P. Kuiper, Peter M. Hoogerbrugge, Monique L. den Boer, Frank N. van Leeuwen

المصدر: Haematologica, Vol 102, Iss 3 (2017)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/8005; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/4b9e33dbdf0346af888f8b42df273b6a

المؤلفون: Beat Bornhauser, Roland P. Kuiper, Steven M. Kornblau, Britt M.T. Vervoort, Jiangyan Yu, Rico Hagelaar, Fieke W Hoff, Frank N. van Leeuwen, Dorette van Ingen Schenau, Maria Pamela Dobay, Trisha M Tee, Laurens T. van der Meer, Silvia Jenni, Jules P.P. Meijerink, Jean-Pierre Bourquin, Miriam Butler

المساهمون: University of Zurich, van Leeuwen, Frank N

المصدر: Blood, 138(23), 2383-2395. AMER SOC HEMATOLOGY
Blood, 138, 23, pp. 2383-2395
Blood, 138, 2383-2395

مصطلحات موضوعية: Treatment response, Asparaginase, 1303 Biochemistry, Lymphoblastic Leukemia, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Immunology, 2720 Hematology, Antineoplastic Agents, Apoptosis, 610 Medicine & health, Biochemistry, 1307 Cell Biology, Mice, chemistry.chemical_compound, Piperidines, Cell Line, Tumor, Agammaglobulinaemia Tyrosine Kinase, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Animals, Humans, CRISPR, Bruton's tyrosine kinase, Amino Acids, chemistry.chemical_classification, 2403 Immunology, biology, Adenine, Cell Biology, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Amino acid, chemistry, 10036 Medical Clinic, Ibrutinib, Cancer research, biology.protein, Tyrosine kinase, Signal Transduction

وصف الملف: application/pdf; blood_btk.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db47fa4b7f953cb27d3df3b78bffe81d
https://doi.org/10.1182/blood.2021011787

المؤلفون: Miriam Butler, Frank N. van Leeuwen, Laurens T. van der Meer

المصدر: Trends in Endocrinology and Metabolism, 32, 6, pp. 367-381
Trends in Endocrinology and Metabolism, 32, 367-381

مصطلحات موضوعية: chemistry.chemical_classification, Treatment response, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Endocrinology, Diabetes and Metabolism, Cancer, 030209 endocrinology & metabolism, Metabolism, Carbohydrate metabolism, medicine.disease, Amino acid, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, chemistry, Downregulation and upregulation, Neoplasms, Cancer cell, medicine, Cancer research, Humans, Amino acid metabolism, Amino Acids, Oxidation-Reduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df025869bd34e61ad52b873768ddc90
https://hdl.handle.net/2066/234011

المؤلفون: Miriam, Butler, Britt M T, Vervoort, Dorette S, van Ingen Schenau, Lieneke, Jongeneel, Jordy C G, van der Zwet, René, Marke, Jules P P, Meijerink, Blanca, Scheijen, Laurens T, van der Meer, Frank N, van Leeuwen

المصدر: Frontiers in oncology. 12

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::169a2de7238ed1263cf25a7939212fc9
https://pubmed.ncbi.nlm.nih.gov/36119546

المؤلفون: Willem Cox, Miriam Butler, Dorette S van Ingen Schenau, Nadia Anderson, Lieke de Groot, Laurens T van der Meer, Frank N van Leeuwen

المصدر: Blood. 140:3132-3133

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1be83d663c323905342b17871bfba409
https://doi.org/10.1182/blood-2022-157118

المؤلفون: Trisha Tee, Titine Ruiter, Danique Wajon, Shuiyan Wu, Ahmed Dahaoui, Dorette S van Ingen Schenau, Laurens T van der Meer, Frank N van Leeuwen

المصدر: Blood. 140:6343-6344

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c8a1edbf526799828d08a57ed980135b
https://doi.org/10.1182/blood-2022-159450

المؤلفون: Britt M T Vervoort, Miriam Butler, Dorette van Ingen Schenau, Vincent H.J. van der Velden, Beat Bornhauser, Jean-Pierre Bourquin, Laurens T van der Meer, Frank N van Leeuwen

المصدر: Blood. 140:3465-3466

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c6b1a2c495e9095bd52bb52a5023e07f
https://doi.org/10.1182/blood-2022-162246

المؤلفون: Miriam Butler, Britt M.T. Vervoort, Dorette S. van Ingen Schenau, Lieneke Jongeneel, Jordy C.G. van der Zwet, René Marke, Jules P.P. Meijerink, Blanca Scheijen, Laurens T. van der Meer, Frank N. van Leeuwen

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, leukemia, glucocorticoids, IKZF1, therapy resistance, AKT, ERK

Relation: https://figshare.com/articles/figure/Image_6_Reversal_of_IKZF1-induced_glucocorticoid_resistance_by_dual_targeting_of_AKT_and_ERK_signaling_pathways_tif/20785285

الاتاحة: https://doi.org/10.3389/fonc.2022.905665.s007
https://figshare.com/articles/figure/Image_6_Reversal_of_IKZF1-induced_glucocorticoid_resistance_by_dual_targeting_of_AKT_and_ERK_signaling_pathways_tif/20785285

المؤلفون: Miriam Butler, Britt M.T. Vervoort, Dorette S. van Ingen Schenau, Lieneke Jongeneel, Jordy C.G. van der Zwet, René Marke, Jules P.P. Meijerink, Blanca Scheijen, Laurens T. van der Meer, Frank N. van Leeuwen

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, leukemia, glucocorticoids, IKZF1, therapy resistance, AKT, ERK

Relation: https://figshare.com/articles/dataset/DataSheet_1_Reversal_of_IKZF1-induced_glucocorticoid_resistance_by_dual_targeting_of_AKT_and_ERK_signaling_pathways_docx/20785264

الاتاحة: https://doi.org/10.3389/fonc.2022.905665.s001
https://figshare.com/articles/dataset/DataSheet_1_Reversal_of_IKZF1-induced_glucocorticoid_resistance_by_dual_targeting_of_AKT_and_ERK_signaling_pathways_docx/20785264

المؤلفون: Esmé Waanders, Blanca Scheijen, Laurens T van der Meer, Simon V van Reijmersdal, Liesbeth van Emst, Yvet Kroeze, Edwin Sonneveld, Peter M Hoogerbrugge, Ad Geurts van Kessel, Frank N van Leeuwen, Roland P Kuiper

المصدر: PLoS Genetics, Vol 8, Iss 2, p e1002533 (2012)

مصطلحات موضوعية: Genetics, QH426-470

Relation: http://europepmc.org/articles/PMC3280973?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404; https://doaj.org/article/e9d7e52f51aa42f59b59e9ea3e9b9e39

الاتاحة: https://doi.org/10.1371/journal.pgen.1002533
https://doaj.org/article/e9d7e52f51aa42f59b59e9ea3e9b9e39

المؤلفون: Frank N. van Leeuwen, Ahmed Dahaoui, Dorette van Ingen Schenau, Laurens T. van der Meer, Rico Hagelaar, Titine Ruiter, Trisha M Tee

المصدر: Blood. 138:2269-2269

مصطلحات موضوعية: Methionine, biology, business.industry, Lymphoblastic Leukemia, Immunology, Cell Biology, Hematology, Biochemistry, chemistry.chemical_compound, KMT2A, chemistry, Cancer research, biology.protein, Medicine, business, Therapeutic strategy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8b40970b0042c0bf9c1242f38e53725d
https://doi.org/10.1182/blood-2021-145308

المؤلفون: Laurens T. van der Meer, Frank N. van Leeuwen, Michael S. Kilberg, Inge M. N. Wortel

المصدر: Trends in Endocrinology and Metabolism, 28, 11, pp. 794-806
Trends in Endocrinology and Metabolism, 28, 794-806

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Endocrinology, Diabetes and Metabolism, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Apoptosis, Activating Transcription Factor 4, Biology, Article, 03 medical and health sciences, Endocrinology, Downregulation and upregulation, Stress, Physiological, Transcription (biology), Neoplasms, Animals, Humans, Epigenetics, Amino Acids, Hypoxia, Transcription factor, ATF4, Adaptation, Physiological, Cell biology, 030104 developmental biology, Cancer cell, Protein Processing, Post-Translational

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b540e01b1fe1ffc818f239cc3e6e39e5
https://hdl.handle.net/2066/181802

المؤلفون: Laurens T. van der Meer, Blanca Scheijen, Laurensia Yuniati, Frank N. van Leeuwen

المصدر: Journal of Cellular Physiology, 234, 5, pp. 5379-5389
Journal of Cellular Physiology, 234, 5379-5389
Journal of Cellular Physiology

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Cell division, antiproliferation, tumor suppressor, Physiology, DNA repair, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Clinical Biochemistry, Biology, Immediate-Early Proteins, B‐cell malignancies, 03 medical and health sciences, 0302 clinical medicine, BTG1, Neoplasms, Mini‐review, BTG2, medicine, Transcriptional regulation, Animals, Humans, Gene, Cell Proliferation, Tumor Suppressor Proteins, Cell Cycle, Mini‐reviews, Cancer, Cell Differentiation, Cell Biology, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Haematopoiesis, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e2e469774eaf68377ad6c51621427f
https://hdl.handle.net/2066/202708

المؤلفون: Jixiu Shan, Marloes Levers, Blanca Scheijen, Caroline Rodenbach, Sander A.L. Palit, Laurensia Yuniati, Dorette van Ingen Schenau, Michael S. Kilberg, Liesbeth van Emst, Frank N. van Leeuwen, Esther Tijchon, Geert Poelmans, Peter M. Hoogerbrugge, Laurens T. van der Meer

المصدر: Oncotarget, 7, 3128-3143
Oncotarget, 7, 3, pp. 3128-3143
Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Protein-Arginine N-Methyltransferases, PRMT1, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Apoptosis, Biology, Activating Transcription Factor 4, Methylation, Mice, 03 medical and health sciences, BTG1, cellular stress, Stress, Physiological, Cell Line, Tumor, medicine, Animals, Humans, ATF4, Molecular Biology, B cell, Mice, Knockout, B-Lymphocytes, Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], Molecular Animal Physiology, leukemia, Fibroblasts, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Neoplasm Proteins, 3. Good health, Mice, Inbred C57BL, Repressor Proteins, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Oncology, Tumor progression, Cancer cell, Knockout mouse, Cancer research, Research Paper

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9720d296f10c218951327044b93448
https://doi.org/10.18632/oncotarget.6519

المؤلفون: Esther Tijchon, Laurensia Yuniati, Mylène Gerritsen, Laurens T. van der Meer, Blanca Scheijen, Peter M. Hoogerbrugge, Frank N. van Leeuwen, Owen Williams, Liesbeth van Emst, Dorette van Ingen Schenau

المصدر: Experimental Hematology, 60, pp. 57-62.e3
Experimental Hematology, 60, 57-62.e3

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Oncogene Proteins, Fusion, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Chromosomal translocation, Biology, Fusion gene, Mice, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Genetics, medicine, Animals, Molecular Biology, Cyclin-Dependent Kinase Inhibitor p16, Mice, Knockout, Regulation of gene expression, Leukemia, Proto-Oncogene Proteins c-ets, Gene Expression Regulation, Leukemic, Tumor Suppressor Proteins, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Fusion protein, Neoplasm Proteins, Repressor Proteins, 030104 developmental biology, 030220 oncology & carcinogenesis, Core Binding Factor Alpha 2 Subunit, embryonic structures, Proto-Oncogene Proteins c-bcl-6, Cancer research, Ectopic expression, Tumor Suppressor Protein p53, BTG1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09abd2f12df9bb5ce02cc4a1cc1136bc
https://hdl.handle.net/2066/190473

المؤلفون: Esmé Waanders, Martin A. Horstmann, Luciano Dalla-Pozza, Nicola C. Venn, Esther Tijchon, Rob Pieters, Peter M. Hoogerbrugge, Laurens T. van der Meer, Judith M. Boer, Frank N. van Leeuwen, Blanca Scheijen, Liesbeth van Emst, Rene Marke, Dorette van Ingen Schenau, Gabriele Escherich, Roland P. Kuiper, Edwin Sonneveld, Rosemary Sutton, Monique L. den Boer

المساهمون: Pediatrics

المصدر: Haematologica, 102, 541-551
Haematologica, 102(3), 541-551. Ferrata Storti Foundation
Haematologica, 102, 3, pp. 541-551
Haematologica

مصطلحات موضوعية: Male, 0301 basic medicine, Adolescent, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Drug resistance, Biology, Ikaros Transcription Factor, Mice, 03 medical and health sciences, 0302 clinical medicine, Recurrence, CDKN2A, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, hemic and lymphatic diseases, Biomarkers, Tumor, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], medicine, Animals, Humans, Genetic Predisposition to Disease, Cumulative incidence, Child, B cell, Mice, Knockout, Tumor Suppressor Proteins, Epistasis, Genetic, Articles, Hematology, Acute Lymphoblastic Leukemia, Prognosis, medicine.disease, Phenotype, Neoplasm Proteins, 3. Good health, Patient Outcome Assessment, Disease Models, Animal, Leukemia, Cell Transformation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Drug Resistance, Neoplasm, Child, Preschool, 030220 oncology & carcinogenesis, Cancer research, Female, PAX5, BTG1, Gene Deletion

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e46f098de70fd46a1e9fb72df4a538
http://hdl.handle.net/2066/169866