المؤلفون: Duncan C. Miller, Tristan Reuillon, Lauren Molyneux, Timothy Blackburn, Simon J. Cook, Noel Edwards, Jane A. Endicott, Bernard T. Golding, Roger J. Griffin, Ian Hardcastle, Suzannah J. Harnor, Amy Heptinstall, Pamela Lochhead, Mathew P. Martin, Nick C. Martin, Stephanie Myers, David R. Newell, Richard A. Noble, Nicole Phillips, Laurent Rigoreau, Huw Thomas, Julie A. Tucker, Lan-Zhen Wang, Michael J. Waring, Ai-Ching Wong, Stephen R. Wedge, Martin E. M. Noble, Celine Cano

المصدر: Journal of Medicinal Chemistry. 65:6513-6540

مصطلحات موضوعية: Drug Discovery, Molecular Medicine, Pyrroles, Mitogen-Activated Protein Kinase 7, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a06ab562a276985938cc66414c34c2
https://doi.org/10.1021/acs.jmedchem.1c01756

المؤلفون: Lauren Molyneux-Dixon

المصدر: AVANCA | CINEMA.

مصطلحات موضوعية: History, Complementary and alternative medicine, Argument, Premise, Narrative structure, Pharmaceutical Science, Pharmacology (medical), Narrative, Source text, Adaptation (computer science), Linguistics, Storytelling, Fictional Works

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ea2ed100af7fc1c9f9c1d97706e7cd
https://doi.org/10.37390/avancacinema.2020.a131

المؤلفون: Simon J. Cook, Mathew P. Martin, Julie A. Tucker, Miller Duncan Charles, Timothy J. Blackburn, Stephanie M. Myers, Ai-Ching Wong, Nick C. Martin, Mercedes Arasta, Martin E.M. Noble, Huw D. Thomas, Ruth H. Bawn, Lan-Zhen Wang, Noel Edwards, Pamela A. Lochhead, Celine Cano, Suzannah J. Harnor, Tristan Reuillon, Laurent Rigoreau, Lauren Molyneux, Roger J. Griffin, David R. Newell, Bernard T. Golding, Tim Hammonds, Amy B. Heptinstall, P.J. Owen, Stephen R. Wedge, Ian R. Hardcastle, Leon Pang, Jane A. Endicott

المساهمون: Myers, Stephanie, Miller, Duncan, Molyneux, Lauren, Arasta, Mercedes, Bawn, Ruth, Blackburn, Timothy, Cook, Simon, Edwards, Noel, Endicott, Jane, Golding, Bernard, Griffin, Roger, Hammonds, Tim, Hardcastle, Ian, Harnor, Suzannah, Heptinstall, Amy, Lochhead, Pamela, Martin, Mathew, Martin, Nick, Newell, Herbie, Owen, Paul, Pang, Leon, Reuillon, Tristan, Rigoreau, Laurent, Thomas, Huw, Tucker, Julie, Wang, Lan-Zhen, Wong, Ai-Ching, Noble, Martin, Wedge, Stephen, Cano, Celine

مصطلحات موضوعية: Angiogenesis, High-throughput screening, Motility, Administration, Oral, Biological Availability, Mice, Nude, Antineoplastic Agents, Cell Cycle Proteins, 01 natural sciences, Mitogen-Activated Protein Kinase 14, 03 medical and health sciences, Mice, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Extracellular, Animals, Humans, IC50, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase 7, 030304 developmental biology, Cell Proliferation, Pharmacology, sub_chemistry, 0303 health sciences, biology, sub_pharmacyandpharmacology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Kinase, Organic Chemistry, Nuclear Proteins, General Medicine, Neoplasms, Experimental, 0104 chemical sciences, Endothelial stem cell, Biochemistry, Mitogen-activated protein kinase, biology.protein, Female, Drug Screening Assays, Antitumor, Transcription Factors

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b20469b74ddfa9b4388aacc50467a77
https://eprints.whiterose.ac.uk/148098/1/ERK5LeadIDPaper_EurJMedChem_2019_04_29.docx

المؤلفون: Duncan C, Miller, Mathew P, Martin, Santosh, Adhikari, Alfie, Brennan, Jane A, Endicott, Bernard T, Golding, Ian R, Hardcastle, Amy, Heptinstall, Stephen, Hobson, Claire, Jennings, Lauren, Molyneux, Yvonne, Ng, Stephen R, Wedge, Martin E M, Noble, Celine, Cano

المصدر: Organic & Biomolecular Chemistry

مصطلحات موضوعية: Nuclear Proteins, Cell Cycle Proteins, Ligands, Proto-Oncogene Mas, DNA-Binding Proteins, Molecular Docking Simulation, Small Molecule Libraries, Chemistry, Protein Domains, Drug Design, Neoplasms, ATPases Associated with Diverse Cellular Activities, Computer-Aided Design, Humans, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d229ca8fbbd4265862c9a21b474faa54
https://pubmed.ncbi.nlm.nih.gov/29469144

المؤلفون: Timothy J. Blackburn, Roger J. Griffin, Tim Hammonds, Betty Cottyn, Ian R. Hardcastle, Sandrine Vidot, Lauren Molyneux, Bernard T. Golding, Celine Cano, William Clegg, Ruth H. Bawn, Louise Bisset, Hing Y. Leung, David R. Newell, Ai-Ching Wong, Stephanie M. Myers, Laurent Rigoreau, Ross W. Harrington

المساهمون: Newcastle University [Newcastle]

المصدر: ACS Combinatorial Science
ACS Combinatorial Science, ACS, 2016, 18, pp.444-455. ⟨10.1021/acscombsci.5b00155⟩
ACS Combinatorial Science (18), 444-455. (2016)

مصطلحات موضوعية: 0301 basic medicine, High-throughput screening, [SDV]Life Sciences [q-bio], Antineoplastic Agents, Plasma protein binding, Computational biology, 01 natural sciences, Mitogen-Activated Protein Kinase 14, 03 medical and health sciences, Structure-Activity Relationship, Neoplasms, High-Throughput Screening Assays, Extracellular, Structure–activity relationship, Humans, Pyrroles, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase 7, Molecular Structure, 010405 organic chemistry, Chemistry, Kinase, General Chemistry, General Medicine, Combinatorial chemistry, Amides, 3. Good health, 0104 chemical sciences, 030104 developmental biology, Kinase binding, Pharmacophore, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002ffb5033573e80911c966b43ada6d9
https://eprints.gla.ac.uk/139945/1/139945.pdf

المؤلفون: Tristan Reuillon, Duncan Miller, Stephanie Myers, Lauren Molyneux, Céline Cano, Ian Hardcastle, Roger Griffin, Laurent Rigoreau, Bernard Golding, Martin Noble

مصطلحات موضوعية: Uncategorised value

Relation: 10779/uos.23428448.v1; https://figshare.com/articles/standard/Pyrrolcarboxamide_derivatives_for_the_inhbition_of_ERK5/23428448

الاتاحة: https://figshare.com/articles/standard/Pyrrolcarboxamide_derivatives_for_the_inhbition_of_ERK5/23428448