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المؤلفون: Pierre Adumeau, René Raavé, Milou Boswinkel, Sandra Heskamp, Hans J. C. T. Wessels, Alain J. van Gool, Mathieu Moreau, Claire Bernhard, Laurène Da Costa, Victor Goncalves, Franck Denat
المصدر: Bioconjugate Chemistry, 33, 3, pp. 530-540
Bioconjugate Chemistry, 33, 530-540مصطلحات موضوعية: Pharmacology, Radioisotopes, Immunoconjugates, Organic Chemistry, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], All institutes and research themes of the Radboud University Medical Center, Cell Line, Tumor, Neoplasms, Positron-Emission Tomography, Humans, Tissue Distribution, Zirconium, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Biotechnology, Fluorescent Dyes
وصف الملف: application/pdf
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المؤلفون: Mathieu Moreau, Olivier Kitten, Alexandre M.M. Dias, Renaud Seigneuric, Jessica Gobbo, François Hermetet, Fabrice Neiers, Pierre-Simon Bellaye, Bertrand Collin, Lucile Dondaine, Guillaume Marcion, Mathieu Cinier, Loïc Briand, Laurène Da Costa, Burhan Uyanik, Carmen Garrido
المساهمون: Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] (ICMUB), Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Institut de Chimie du CNRS (INC), Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER, Affilogic SAS, French National Research Agency under the program 'Investissements d’Avenir, the Institut National du Cancer, and the Conseil Régional de Bourgogne., ANR-11-LABX-0021,Lipstic,Lipoprotéines et santé : prévention et traitement des maladies inflammatoires non vasculaires et du(2011), ANR-15-IDEX-0003,BFC,ISITE ' BFC(2015)
المصدر: International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (12), pp.3019-3031. ⟨10.1002/ijc.33485⟩مصطلحات موضوعية: Cancer Research, Mice, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Immune system, Peptide Library, In vivo, Cell Line, Tumor, Heat shock protein, Tumor Microenvironment, medicine, Animals, Humans, Cytotoxic T cell, HSP110 Heat-Shock Proteins, small peptide molecules, Tumor microenvironment, anticancer targeted therapy, biology, Chemistry, Macrophages, Cancer, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, medicine.disease, Xenograft Model Antitumor Assays, Peptide Fragments, In vitro, 3. Good health, Nanofitins, Oncology, Positron-Emission Tomography, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Antibody, Colorectal Neoplasms, HSP110
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المؤلفون: René, Raavé, Gerwin, Sandker, Pierre, Adumeau, Christian Borch, Jacobsen, Floriane, Mangin, Michel, Meyer, Mathieu, Moreau, Claire, Bernhard, Laurène, Da Costa, Adrien, Dubois, Victor, Goncalves, Magnus, Gustafsson, Mark, Rijpkema, Otto, Boerman, Jean-Claude, Chambron, Sandra, Heskamp, Franck, Denat
المصدر: European Journal of Nuclear Medicine and Molecular Imaging
مصطلحات موضوعية: Radioisotopes, DFO, Original Article, DFOcyclo, Monoclonal antibodies, Zirconium, Radiopharmaceuticals, immunoPET, 89Zr
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المؤلفون: René Raavé, Magnus Gustafsson, Otto C. Boerman, Laurène Da Costa, Christian Borch Jacobsen, Victor Goncalves, Gerwin Sandker, Mark Rijpkema, Jean-Claude Chambron, Floriane Mangin, Adrien Dubois, Franck Denat, Claire Bernhard, Michel Meyer, Sandra Heskamp, Pierre Adumeau, Mathieu Moreau
المساهمون: Radboud University Medical Center [Nijmegen], Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] (ICMUB), Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Institut de Chimie du CNRS (INC), Novo Nordisk A/S, Institut de Chimie de Strasbourg, Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)
المصدر: European Journal of Nuclear Medicine and Molecular Imaging
European Journal of Nuclear Medicine and Molecular Imaging, Springer Verlag (Germany), 2019, 46 (9), pp.1966-1977. ⟨10.1007/s00259-019-04343-2⟩
European Journal of Nuclear Medicine and Molecular Imaging, 46, 1966-1977
European Journal of Nuclear Medicine and Molecular Imaging, 46, 9, pp. 1966-1977مصطلحات موضوعية: DFO, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, media_common.quotation_subject, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], Pharmacology, 89Zr, 030218 nuclear medicine & medical imaging, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, In vivo, Distribution (pharmacology), [CHIM]Chemical Sciences, Radiology, Nuclear Medicine and imaging, Chelation, DFOcyclo, [CHIM.COOR]Chemical Sciences/Coordination chemistry, skin and connective tissue diseases, Internalization, IC50, media_common, Chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, General Medicine, In vitro, 3. Good health, Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], 030220 oncology & carcinogenesis, Monoclonal antibodies, immunoPET, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Ex vivo, Conjugate
وصف الملف: application/pdf
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المؤلفون: René, Raavé, Gerwin, Sandker, Pierre, Adumeau, Christian Borch, Jacobsen, Floriane, Mangin, Michel, Meyer, Mathieu, Moreau, Claire, Bernhard, Laurène, Da Costa, Adrien, Dubois, Victor, Goncalves, Magnus, Gustafsson, Mark, Rijpkema, Otto, Boerman, Jean-Claude, Chambron, Sandra, Heskamp, Franck, Denat
المصدر: European Journal of Nuclear Medicine and Molecular Imaging
مصطلحات موضوعية: Radioisotopes, Mice, Cell Transformation, Neoplastic, Cell Line, Tumor, Positron Emission Tomography Computed Tomography, Animals, Humans, Female, Tissue Distribution, Zirconium, Deferoxamine, Letter to the Editor
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المؤلفون: Roberto Cirilli, Carmen Mirabelli, Romano Silvestri, Els Scheers, Giuseppe La Regina, Patrice Vanelle, Laurène Da Costa, Adriano Casulli, Thierry Terme, Antonio Coluccia, Carole Di Giorgio, Johan Neyts, Manon Roche
المساهمون: Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Assistance Publique - Hôpitaux de Marseille (APHM), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Rega Institute for Medical Research [Leuven, België], Dipartimento del Farmaco, Istituto Superiore di Sanita [Rome], Department of Drug Chemistry and Technologies = Dipartimento di Chimica et Tecnologie del Farmaco [Roma], Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome]-Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Istituto Superiore di Sanità (ISS), Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA)
المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2018, 61 (18), pp.8402-8416. ⟨10.1021/acs.jmedchem.8b00931⟩
Journal of Medicinal Chemistry, 2018, 61 (18), pp.8402-8416. ⟨10.1021/acs.jmedchem.8b00931⟩مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Drug, Rhinovirus infection, Protein Conformation, In vitro genotoxicity, media_common.quotation_subject, [SDV]Life Sciences [q-bio], RV, Pyrazole, Virus Replication, medicine.disease_cause, Antiviral Agents, Rats, Sprague-Dawley, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Enterovirus Infections, medicine, Animals, Humans, [CHIM]Chemical Sciences, media_common, VP1 protein, heterocycles, Micronucleus Tests, Molecular Structure, Chemistry, molecular modelling studies, rhinovirus, pyrazole, Virology, Rats, 3. Good health, capsid binder, 030104 developmental biology, Drug Design, Pyrazoles, Molecular Medicine, Structure based, Rhinovirus, chiral inhibitors, HeLa Cells
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المؤلفون: Romano Silvestri, Alessia Rosetti, Roberto Cirilli, Manon Roche, Carmen Mirabelli, Thierry Terme, Antonio Coluccia, Johan Neyts, Els Scheers, Patrice Vanelle, Laurène Da Costa
المساهمون: Department of Medicinal Chemistry and Technologies, Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Assistance Publique - Hôpitaux de Marseille (APHM), Institut de Chimie Radicalaire (ICR), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Laboratory of Virology and Chemotherapy [KU Leuven], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven)-Rega Institute of Medical Research [Leuven, Belgium], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Dipartimento del Farmaco, Istituto Superiore di Sanita [Rome], Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Istituto Superiore di Sanità (ISS)
المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2017, 140, pp.528--541. ⟨10.1016/j.ejmech.2017.09.036⟩
European Journal of Medicinal Chemistry, 2017, 140, pp.528--541. ⟨10.1016/j.ejmech.2017.09.036⟩مصطلحات موضوعية: 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, replication, Magnetic Resonance Spectroscopy, Rhinovirus, absolute-configuration, compound, In silico, Capsid-binder, Heterocycles, virus, medicine.disease_cause, Antiviral Agents, Virus, Enantioseparation, 03 medical and health sciences, Structure-Activity Relationship, RV-B14, VP1 protein, capsid-binder, enantioseparation, Mosher's method, heterocycles, Heterocyclic Compounds, Drug Discovery, inhibitors, medicine, Structure–activity relationship, Humans, [CHIM]Chemical Sciences, 14 infection, Asthma, Pharmacology, ICAM-1, Chemistry, Circular Dichroism, Organic Chemistry, Common cold, Stereoisomerism, General Medicine, dynamics, medicine.disease, Virology, common cold, 3. Good health, Molecular Docking Simulation, rv-b14, 030104 developmental biology, Enterovirus, entry, HeLa Cells
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المؤلفون: Romano Silvestri, Antonio Coluccia, Manon Roche, Patrice Vanelle, Laurène Da Costa, Thierry Terme, Johan Neyts, Els Scheers, Pieter Leyssen
المساهمون: Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Rega Institute for Medical Research [Leuven, België], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Department of Medicinal Chemistry and Technologies, Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], This work was supported by the Centre National de la Recherche Scientifique., We express our thanks to Youssef Kabri, and Omar Khoumeri which were an enormous help in my everyday work and to Vincent Remusat for 1H and 13C NMR spectra recording. The antiviral work was performed by Els Scheers, Ph.D. in Rega Institute for Medical Research., Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA)
المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2016, 115, pp.453--462. ⟨10.1016/j.ejmech.2016.03.049⟩
European Journal of Medicinal Chemistry, 2016, 115, pp.453--462. ⟨10.1016/j.ejmech.2016.03.049⟩مصطلحات موضوعية: 0301 basic medicine, Serotype, Models, Molecular, Rhinovirus, compound, design, MESH: Antiviral Agents/pharmacology, Pharmacology, medicine.disease_cause, 01 natural sciences, HeLa, Drug Discovery, Benzene Derivatives, media_common, capsid inhibitors, HRV14, in silico design, TDAE, VP1 protein, drug discovery3003 pharmaceutical science, organic chemistry, pharmacology, MESH: Benzene Derivatives/pharmacology, In silico design, original synthesis, biology, Chemistry, Common cold, General Medicine, 3. Good health, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Toxicity, hrv14, 3c protease, strategy, MESH: Models, Molecular, Drug, replication, media_common.quotation_subject, Antiviral Agents, 03 medical and health sciences, tdae methodology, MESH: Benzene Derivatives/chemistry, tdae, medicine, Potency, Humans, [CHIM]Chemical Sciences, MESH: Rhinovirus/chemistry, attachment, Asthma, MESH: Humans, 010405 organic chemistry, MESH: Antiviral Agents/chemistry, Organic Chemistry, biology.organism_classification, medicine.disease, Virology, common cold, Capsid inhibitors, 0104 chemical sciences, 030104 developmental biology, MESH: HeLa Cells, derivatives, HeLa Cells
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المؤلفون: Marine Peuchmaur, Laurène Da Costa, Hugues Bonnet, Sabine Chierici, Samir Yahiaoui, Ahcène Boumendjel, Wei Yi, Laurent Lunven
المساهمون: Département de Chimie Moléculaire - Ingéniérie et Intéractions BioMoléculaires (DCM - I2BM), Département de Chimie Moléculaire (DCM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Physique et mécanique des milieux hétérogenes (UMR 7636) (PMMH), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Département de pharmacochimie moléculaire (DPM ), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Institut des Sciences Moléculaires (ISM), Centre National de la Recherche Scientifique (CNRS)-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Université Sciences et Technologies - Bordeaux 1-Université Montesquieu - Bordeaux 4-Institut de Chimie du CNRS (INC)
المصدر: ACS Chemical Neuroscience
ACS Chemical Neuroscience, American Chemical Society (ACS), 2016, 7 (7), pp.995-1003. ⟨10.1021/acschemneuro.6b00102⟩مصطلحات موضوعية: 0301 basic medicine, Circular dichroism, Physiology, Stereochemistry, Cognitive Neuroscience, Context (language use), Peptide, tau Proteins, Microscopy, Atomic Force, Biochemistry, Fluorescence, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Aurone, Molecule, Humans, ComputingMilieux_MISCELLANEOUS, Benzofurans, chemistry.chemical_classification, Chemistry, Circular Dichroism, Neurofibrillary Tangles, Cell Biology, General Medicine, In vitro, 3. Good health, 030104 developmental biology, Models, Chemical, Thioflavin, Myricetin, Peptides, 030217 neurology & neurosurgery