المؤلفون: Fairbairn, Leslie J, Chinnasamy, Nachimuthu, Lashford, Linda S, Chinnasamy, Dhanalakshmi, Rafferty, Joseph A

المصدر: Cancer Gene Therapy ; volume 7, issue 2, page 233-239 ; ISSN 0929-1903 1476-5500

الاتاحة: http://dx.doi.org/10.1038/sj.cgt.7700120
https://www.nature.com/articles/7700120.pdf
https://www.nature.com/articles/7700120

المؤلفون: Lashford, Linda S.

المصدر: Annals of Medicine ; volume 29, issue 1, page 1-4 ; ISSN 0785-3890 1365-2060

الاتاحة: http://dx.doi.org/10.3109/07853899708998737
http://www.tandfonline.com/doi/pdf/10.3109/07853899708998737

المؤلفون: Taylor, Roger E., Bailey, Clifford C., Robinson, Kathryn J., Weston, Claire L., Walker, David A., Ellison, David, Ironside, James, Pizer, Barry L., Lashford, Linda S.

المصدر: European Journal of Cancer ; volume 41, issue 5, page 727-734 ; ISSN 0959-8049

الاتاحة: http://dx.doi.org/10.1016/j.ejca.2004.12.017
https://api.elsevier.com/content/article/PII:S0959804904010391?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0959804904010391?httpAccept=text/plain

المؤلفون: Taylor, Roger E, Bailey, Clifford C, Robinson, Kathryn J, Weston, Claire L, Ellison, David, Ironside, James, Lucraft, Helen, Gilbertson, Richard, Tait, Diana M, Saran, Frank, Walker, David A, Pizer, Barry L, Lashford, Linda S

المصدر: International Journal of Radiation Oncology*Biology*Physics ; volume 58, issue 4, page 1184-1193 ; ISSN 0360-3016

الاتاحة: http://dx.doi.org/10.1016/j.ijrobp.2003.08.010
https://api.elsevier.com/content/article/PII:S0360301603017668?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0360301603017668?httpAccept=text/plain

المؤلفون: Turner, Suzanne D, Wijnhoven, S W, Tinwell, H, Lashford, Linda S, Rafferty, Joseph A, Ashby, J, Vrieling, H, Fairbairn, Leslie J

المساهمون: Gene Therapy Group, Christie Hospital (NHS) Trust, Wilmslow Road, Manchester M20 4BX, UK. suzanne.turner@bbsrc.ac.uk

مصطلحات موضوعية: Adenine Phosphoribosyltransferase, Animals, Antineoplastic Agents, Phytogenic, Comet Assay, DNA Topoisomerases, Type II, Etoposide, Humans, Hypoxanthine Phosphoribosyltransferase, In Situ Hybridization, Fluorescence, Male, Mice, Micronucleus Tests, Mutagenicity Tests, Mutagens, Spleen

Relation: Assays to predict the genotoxicity of the chromosomal mutagen etoposide -- focussing on the best assay. 2001, 493 (1-2):139-47 Mutat. Res.; http://hdl.handle.net/10541/84159; Mutation Research

الاتاحة: http://hdl.handle.net/10541/84159

المؤلفون: Bellantuono, Ilaria, Lashford, Linda S, Rafferty, Joseph A, Fairbairn, Leslie J

المساهمون: Department of Immunology, Imperial College School of Medicine, The Hammersmith Hospital, Du Cane Road, London, W12 0NN, United Kingdom. i.bellantuono@ic.ac.uk

مصطلحات موضوعية: 3T3 Cells, Animals, Blotting, Northern, Southern, Western, DNA, Complementary, Gene Transfer Techniques, Genetic Vectors, Humans, Membrane Glycoproteins, Mice, NADPH Oxidase, RNA, Viral, Retroviridae, Viral Proteins

Relation: The expression of full length Gp91-phox protein is associated with reduced amphotropic retroviral production. 2000, 85 (5):451-7 Haematologica; http://hdl.handle.net/10541/86689; Haematologica

الاتاحة: http://hdl.handle.net/10541/86689

المؤلفون: Marples, B, Scott, S D, Hendry, Jolyon H, Embleton, M J, Lashford, Linda S, Margison, Geoffrey P

المساهمون: Cancer Research Campaign Section of Genome Damage and Repair, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Breast Cancer, Cultured Tumour Cells, Adenocarcinoma, Breast Neoplasms, Female, Ganciclovir, Gene Therapy, Gene Transfer Techniques, Glioblastoma, Humans, Promoter Regions, Genetic, Radiation-Sensitizing Agents, Simplexvirus, Thymidine Kinase, Transcription, Tumor Cells, Cultured

Relation: Development of synthetic promoters for radiation-mediated gene therapy. 2000, 7 (6):511-7 Gene Ther.; http://hdl.handle.net/10541/86683; Gene Therapy

الاتاحة: http://hdl.handle.net/10541/86683
https://doi.org/10.1038/sj.gt.3301116

المؤلفون: Fairbairn, Leslie J, Rafferty, Joseph A, Lashford, Linda S

المساهمون: Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Cancer, Animals, Antineoplastic Agents, Bone Marrow, Bone Marrow Transplantation, DNA Repair, Drug Resistance, Female, Gene Therapy, Genetic Engineering, Humans, Male, Mice, Neoplasms, O(6)-Methylguanine-DNA Methyltransferase

Relation: Engineering drug resistance in human cells. 2000, 25 Suppl 2:S110-3 Bone Marrow Transplant.; http://hdl.handle.net/10541/86686; Bone Marrow Transplantation

الاتاحة: http://hdl.handle.net/10541/86686

المؤلفون: Scott, S D, Marples, B, Hendry, Jolyon H, Lashford, Linda S, Embleton, M J, Hunter, Robin D, Howell, Anthony, Margison, Geoffrey P

المساهمون: Cancer Research Campaign Section of Genome Damage and Repair, Paterson Institute for Cancer Research, Christie Hospital (NHS) Trust, Manchester, UK.

مصطلحات موضوعية: Cancer, Cultured Tumour Cells, Antiviral Agents, Cell Division, Cytomegalovirus, Flow Cytometry, Ganciclovir, Gene Expression, Gene Therapy, Gene Transfer Techniques, Green Fluorescent Proteins, Humans, Integrases, Luminescent Proteins, Neoplasms, Promoter Regions, Genetic, Simplexvirus, Thymidine Kinase, Tumor Cells, Cultured, Viral Proteins

Relation: A radiation-controlled molecular switch for use in gene therapy of cancer. 2000, 7 (13):1121-5 Gene Ther.; http://hdl.handle.net/10541/86680; Gene Therapy

الاتاحة: http://hdl.handle.net/10541/86680

المؤلفون: Turner, S D, Rafferty, Joseph A, Fairbairn, Leslie J, Ashby, J, Tinwell, H, Eckert, H G, Baum, C, Lashford, Linda S

المساهمون: Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Animals, Antineoplastic Agents, Phytogenic, Bone Marrow, Drug Administration Routes, Drug Administration Schedule, Etoposide, Female, Gene Transfer, Horizontal, Male, Mice, Micronucleus Tests, P-Glycoprotein

Relation: The effects of dose, route of administration, drug scheduling and MDR-1 gene transfer on the genotoxicity of etoposide in bone marrow. 2000, 14 (10):1796-802 Leukemia; http://hdl.handle.net/10541/86674; Leukemia

الاتاحة: http://hdl.handle.net/10541/86674

المؤلفون: Jelinek, J, Rafferty, Joseph A, Cmejla, R, Hildinger, M, Chinnasamy, Dhanalakshmi, Lashford, Linda S, Ostertag, W, Margison, Geoffrey P, Dexter, T Michael, Fairbairn, Leslie J, Baum, Christopher

المساهمون: Institute of Haematology and Blood Transfusion, Praha, Czech Republic.

مصطلحات موضوعية: Cancer Drug Resistance, Haematopoietic Stem Cells, Antineoplastic Agents, Drug Resistance, Multiple, Neoplasm, Genes, MDR, Genetic Vectors, Hematopoietic Stem Cells, Humans, K562 Cells, O(6)-Methylguanine-DNA Methyltransferase, Retroviridae, Transduction, Genetic

Relation: A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents. 1999, 6 (8):1489-93 Gene Ther.; http://hdl.handle.net/10541/91413; Gene Therapy

الاتاحة: http://hdl.handle.net/10541/91413
https://doi.org/10.1038/sj.gt.3300962

المؤلفون: Chinnasamy, Nachimuthu, Rafferty, Joseph A, Lashford, Linda S, Chinnasamy, Dhanalakshmi, Margison, Geoffrey P, Thatcher, Nick, Dexter, T Michael, Fairbairn, Leslie J

المساهمون: CRC Sections of Genome Damage and Repair, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Haematopoietic Stem Cells, Cancer Drug Resistance, Animals, Antineoplastic Agents, Carmustine, Cells, Cultured, Colony-Forming Units Assay, Drug Resistance, Neoplasm, Erythrocytes, Gene Therapy, Granulocytes, Guanine, Hematopoietic Stem Cells, Humans, Immunohistochemistry, Macrophages, Male, Mice, Micronucleus Tests, Mutagens, Mutation, Nucleotidyltransferases, Spleen, Transduction, Genetic

Relation: Protection of committed murine haemopoietic progenitors against BCNU toxicity does not predict protection of primitive, multipotent spleen colony-forming cells - implications for chemoprotective gene therapy. 1999, 13 (11):1776-83 Leukemia; http://hdl.handle.net/10541/90155; Leukemia

الاتاحة: http://hdl.handle.net/10541/90155

المؤلفون: Michelagnoli, M P, Lewis, I J, Gattamaneni, Rao, Bailey, C C, Lashford, Linda S

المساهمون: Paediatric Haematology and Oncology Unit, St James University Hospital, Leeds, UK.

مصطلحات موضوعية: Bone Cancer, Adolescent, Antineoplastic Combined Chemotherapy Protocols, Bone Neoplasms, Child, Drug Administration Schedule, Etoposide, Feasibility Studies, Female, Humans, Ifosfamide, Male, Methotrexate, Osteosarcoma, Recurrence, Retrospective Studies

Relation: Ifosfamide/etoposide alternating with high-dose methotrexate: evaluation of a chemotherapy regimen for poor-risk osteosarcoma. 1999, 79 (7-8):1174-8 Br. J. Cancer; http://hdl.handle.net/10541/88054; British Journal of Cancer

الاتاحة: http://hdl.handle.net/10541/88054
https://doi.org/10.1038/sj.bjc.6690187

المؤلفون: Makin, Guy W J, Eden, Tim O B, Lashford, Linda S, Moppett, John, Gerrard, Mary P, Davies, Helena A, Powell, Colin V, Campbell, Alastair N, Child, H Frances

المساهمون: Academic Unit of Pediatric Oncology, Christie Hospital NHS Trust, Withington, Manchester, United Kingdom.

مصطلحات موضوعية: Skin Cancer, Central Nervous System Cancer, Central Nervous System Neoplasms, Child, Preschool, Fatal Outcome, Female, Humans, Male, Melanoma, Nevus, Pigmented, Skin Neoplasms

Relation: Leptomeningeal melanoma in childhood. 1999, 86 (5):878-86 Cancer; http://hdl.handle.net/10541/88014; Cancer

الاتاحة: http://hdl.handle.net/10541/88014
https://doi.org/10.1002/(SICI)1097-0142(19990901)86:5<878::AID-CNCR26>3.0.CO;2-Y

المؤلفون: Makin, Guy W. J., Eden, Osborn B., Lashford, Linda S., Moppett, John, Gerrard, Mary P., Davies, Helena A., Powell, Colin V. E., Campbell, Alastair N., Child, H. Frances

المصدر: Cancer ; volume 86, issue 5, page 878-886 ; ISSN 0008-543X 1097-0142

الاتاحة: http://dx.doi.org/10.1002/(sici)1097-0142(19990901)86:5%3C878::aid-cncr26%3E3.0.co%3B2-y
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F(SICI)1097-0142(19990901)86:5%3C878::AID-CNCR26%3E3.0.CO%3B2-Y
https://onlinelibrary.wiley.com/doi/full/10.1002/(SICI)1097-0142(19990901)86:5%3C878::AID-CNCR26%3E3.0.CO%3B2-Y

المؤلفون: Baum, Christopher, Fairbairn, Leslie J., Hildinger, Markus, Lashford, Linda S., Hegewisch-Becker, Susanna, Rafferty, Joseph A.

المصدر: Expert Reviews in Molecular Medicine ; volume 1, issue 12 ; ISSN 1462-3994

الاتاحة: http://dx.doi.org/10.1017/s1462399499000769
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1462399499000769

المؤلفون: Wynn, Robert F, Cross, Michael A, Hatton, C, Will, A M, Lashford, Linda S, Dexter, T Michael, Testa, Nydia G

المساهمون: Cancer Research Campaign Department of Experimental Haematology, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK.

مصطلحات موضوعية: Haematopoiesis, Haematopoietic Stem Cells, Adolescent, Bone Marrow Transplantation, Cell Aging, Child, Preschool, Female, Hematopoiesis, Hematopoietic Stem Cells, Humans, Male, Telomere, Time Factors, Transplantation, Homologous

Relation: Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants. 1998, 351 (9097):178-81 Lancet; 9449873; http://hdl.handle.net/10541/92345; Lancet

الاتاحة: http://hdl.handle.net/10541/92345
https://doi.org/10.1016/S0140-6736(97)08256-1

المؤلفون: Chinnasamy, Nachimuthu, Rafferty, Joseph A, Hickson, Ian, Lashford, Linda S, Longhurst, S J, Thatcher, Nick, Margison, Geoffrey P, Dexter, T Michael, Fairbairn, Leslie J

المساهمون: CRC Sections of Genome Damage and Repair, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Animals, Antineoplastic Agents, Alkylating, Bone Marrow Cells, Cell Survival, Dacarbazine, Gene Expression, Gene Transfer Techniques, Genetic Vectors, Male, Mice, Inbred Strains, O(6)-Methylguanine-DNA Methyltransferase, Polymerase Chain Reaction, Retroviridae, Spleen, Stem Cells

Relation: Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase. 1998, 5 (6):842-7 Gene Ther.; 9747465; http://hdl.handle.net/10541/92044; Gene Therapy

الاتاحة: http://hdl.handle.net/10541/92044
https://doi.org/10.1038/sj.gt.3300699

المؤلفون: Hickson, Ian, Fairbairn, Leslie J, Chinnasamy, Nachimuthu, Lashford, Linda S, Thatcher, Nick, Margison, Geoffrey P, Dexter, T Michael, Rafferty, Joseph A

المساهمون: CRC Section of Haemopoietic Cell, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Haematopoietic Stem Cells, Antigens, CD34, Antineoplastic Agents, Alkylating, Cell Line, Cell Survival, Dacarbazine, Gene Transfer Techniques, Genetic Vectors, Guanine, Hematopoietic Stem Cells, Humans, Nitrogen Mustard Compounds, O(6)-Methylguanine-DNA Methyltransferase, Polymerase Chain Reaction, Retroviridae

Relation: Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro. 1998, 5 (6):835-41 Gene Ther.; 9747464; http://hdl.handle.net/10541/92054; Gene Therapy

الاتاحة: http://hdl.handle.net/10541/92054
https://doi.org/10.1038/sj.gt.3300698

المؤلفون: Hesketh, E, Eden, Tim O B, Gattamaneni, Rao, Campbell, Richard H A, Jenney, M E, Lashford, Linda S

المساهمون: Department of Paediatric Oncology, Manchester Children's Hospital and Christie Hospital NHS Trust, UK.

مصطلحات موضوعية: Spinal Cord Cancer, Child, Preschool, Female, Humans, Infant, Neural Crest, Neuroblastoma, Polyradiculoneuropathy, Rhabdomyosarcoma, Spinal Cord Compression, Spinal Cord Neoplasms, Teratoma

Relation: Spinal cord compression--do we miss it? 1998, 87 (4):452-4 Acta Paediatr.; 9628305; http://hdl.handle.net/10541/91976; Acta Paediatrica

الاتاحة: http://hdl.handle.net/10541/91976
https://doi.org/10.1111/j.1651-2227.1998.tb01477.x