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1Academic Journal
المؤلفون: María A. Urbaneja, Lars Skjærven, Oscar Aubi, Jarl Underhaug, David J. López, Igor Arregi, Marián Alonso-Mariño, Andoni Cuevas, José A. Rodríguez, Aurora Martinez, Sonia Bañuelos
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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2Academic Journal
المؤلفون: Helene J Bustad, Lars Skjaerven, Ming Ying, Øyvind Halskau, Anne Baumann, David Rodriguez-Larrea, Miguel Costas, Jarl Underhaug, Jose M Sanchez-Ruiz, Aurora Martinez
المصدر: PLoS ONE, Vol 7, Iss 11, p e49671 (2012)
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Lars Skjaerven, Barry Grant, Arturo Muga, Knut Teigen, J Andrew McCammon, Nathalie Reuter, Aurora Martinez
المصدر: PLoS Computational Biology, Vol 7, Iss 3, p e1002004 (2011)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Anastasiia Klimashevskaia, Mehdi Elahi, Dietmar Jannach, Christoph Trattner, Lars Skjærven
المصدر: Communications in Computer and Information Science ISBN: 9783031093159
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المؤلفون: Fredrik Gullaksen Johannessen, Marte I. Flydal, Lars Skjærven, Rafael Fernandez-Leiro, Siseth Martínez-Caballero, Juan A. Hermoso, Aurora Martinez, Martín Alcorlo-Pagés
المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Research Council of Norway, Western Norway Regional Health Authority, ALBA Synchrotron, European Synchrotron Radiation Facility
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Phenylalanine hydroxylase, Allosteric regulation, Phenylalanine, Molecular Dynamics Simulation, 03 medical and health sciences, Oxidoreductase, Phenylketonurias, medicine, Humans, Phenylketonuria, X-ray crystallography, Cryo-EM, chemistry.chemical_classification, Multidisciplinary, 030102 biochemistry & molecular biology, biology, Human phenylalanine hydroxylase, Mutagenesis, Phenylalanine Hydroxylase, Active site, Tetrahydrobiopterin, Biological Sciences, Biopterin, Pharmacological chaperone, 030104 developmental biology, chemistry, Mutation, Mutagenesis, Site-Directed, biology.protein, Biophysics, medicine.drug
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المؤلفون: Eivind Fiskerud, Kristian Tolonen, Erik Knudsen, Igor Pipkin, Øyvind Holmstad, Loek Vredenberg, Agnes Stenbom, Lars Skjærven, Dietmar Jannach, Adrian Oesch, Helle Sjøvaag, Mehdi Elahi, Eivind Throndsen, Christoph Trattner
المصدر: AI and Ethics
مصطلحات موضوعية: business.industry, Computer science, Mechanical Engineering, media_common.quotation_subject, medier, Internet privacy, Energy Engineering and Power Technology, nettmedier, Management Science and Operations Research, Recommender system, Lead (geology), Reading (process), Misinformation, anbefalinger på medier, business, Samfunnsvitenskap: 200::Medievitenskap og journalistikk: 310 [VDP], media_common
وصف الملف: application/pdf
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المؤلفون: Xin-Qiu Yao, Lars Skjærven, Barry J. Grant
المصدر: Protein science : a publication of the Protein Society, vol 30, iss 1
Protein Sciمصطلحات موضوعية: Protein family, Computer science, Protein Conformation, principal component analysis, 1.1 Normal biological development and functioning, Biophysics, Molecular Dynamics Simulation, computer.software_genre, distance matrix analysis, Biochemistry, 03 medical and health sciences, Structural bioinformatics, Databases, protein sequence, Protein sequencing, Underpinning research, protein structure, Databases, Protein, Other Information and Computing Sciences, Molecular Biology, 030304 developmental biology, 0303 health sciences, Tools for Protein Science, Protein, 030302 biochemistry & molecular biology, Proteins, Computational Biology, Computation Theory and Mathematics, structural bioinformatics, allosteric regulation, molecular dynamics, Workflow, Distance matrix, normal mode analysis, Principal component analysis, Data mining, Generic health relevance, Biochemistry and Cell Biology, protein structure network, computer, Distance matrices in phylogeny, Software, functional dynamics, Network analysis
وصف الملف: application/pdf
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المؤلفون: Y. Rancel, Joaquín Otón, Javier Mota, Roberto Melero, Laura del Cano, Roberto Marabini, Slavica Jonic, Rubén J. Sánchez-García, A. Jimenez, Carlos Oscar S. Sorzano, David Maluenda, José Luis Vilas, Pablo Conesa, Joan Segura, Lars Skjærven, Tomáš Majtner, Erney Ramírez-Aportela, Marta Martínez, José María Carazo
المساهمون: Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), Department of Optics and Optometry, Universitat Politècnica de Catalunya [Barcelona] (UPC), Fac Ciencia & Tecnol, Dpto Quim Fis (Labquimac), Univ Basque Country, GN7 of the National Institute for Bioinformatics (INB) and Biocomputing Unit, Centro Nacional de Biotecnología (CSIC), European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, Escuela Politécnica Superior, Univ. Autónoma de Madrid, Escuela Politecnica Superior, Department of Structure of Macromolecules, Centro Nacional de Biotecnología (CNB-CSIC), Universidad Autónoma de Madrid, Centro Nacional de Biotecnología [Madrid] (CNB-CSIC), Biocomputing Unit [Madrid], Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Instituto de Salud Carlos III, European Commission
المصدر: Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2019, 35 (14), pp.2427-2433. ⟨10.1093/bioinformatics/bty985⟩
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Statistics and Probability, Physics, 0303 health sciences, X-Rays, Cryoelectron Microscopy, 030302 biochemistry & molecular biology, Biochemistry, Computer Science Applications, Nuclear physics, 03 medical and health sciences, Computational Mathematics, X-Ray Diffraction, Computational Theory and Mathematics, Scattering, Small Angle, media_common.cataloged_instance, Christian ministry, European union, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, Molecular Biology, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, media_common
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المؤلفون: Barry J, Grant, Lars, Skjærven, Xin-Qiu, Yao
المصدر: Methods in molecular biology (Clifton, N.J.). 2112
مصطلحات موضوعية: Databases, Factual, Protein Conformation, Data Interpretation, Statistical, Proteins, Sequence Alignment, Software
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المؤلفون: Lars Skjærven, Xin-Qiu Yao, Barry J. Grant
المصدر: Methods in Molecular Biology ISBN: 9781071602690
مصطلحات موضوعية: Structure (mathematical logic), 0303 health sciences, Sequence, Information retrieval, Computer science, Protein dynamics, Protein structure analysis, 02 engineering and technology, Protein superfamily, 021001 nanoscience & nanotechnology, 03 medical and health sciences, Structural bioinformatics, Protein structure, 0210 nano-technology, Cluster analysis, Word (computer architecture), 030304 developmental biology
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المؤلفون: Sverre Sandberg, Marta Vorland, Karen Toska, Caroline Schmitt, Sylvie Simonin, Juha P. Kallio, Helene J. Bustad, Lars Skjærven, Philippe Lettéron, Aurora Martinez, Jarl Underhaug
المساهمون: Centre Français des Porphyries, Hôpital Louis Mourier - AP-HP [Colombes], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Haukeland University Hospital, University of Bergen (UiB), Centre Français des Porphyrines, Centre de recherche biomédicale Bichat-Beaujon (CRB3), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Department of Public Health and Primary Health Care, Hopital Louis Mourier - AP-HP [Colombes], University of Bergen (UIB)
المصدر: Molecular Therapy
Molecular Therapy, Cell Press, 2019, ⟨10.1016/j.ymthe.2019.11.010⟩
Molecular Therapy, Nature Publishing Group, 2019, ⟨10.1016/j.ymthe.2019.11.010⟩مصطلحات موضوعية: Protein Folding, medicine.medical_treatment, Drug Evaluation, Preclinical, Liver transplantation, protein stabilization, heme synthesis, Mice, 0302 clinical medicine, Drug Discovery, Medicine, acute intermittent porphyria, Molecular Targeted Therapy, ComputingMilieux_MISCELLANEOUS, Acute intermittent porphyria, Mice, Knockout, 0303 health sciences, Autosomal dominant trait, hydroxymethylbilane synthase, 3. Good health, Pharmacological chaperone, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Molecular Medicine, Original Article, Protein stabilization, medicine.drug, Hydroxymethylbilane Synthase, Small Molecule Libraries, pharmacological chaperones, 03 medical and health sciences, Structure-Activity Relationship, [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication, Genetics, inborn error of metabolism, Animals, Humans, Molecular Biology, 030304 developmental biology, Pharmacology, business.industry, Proteins, Reproducibility of Results, medicine.disease, mouse model of AIP, Disease Models, Animal, Inborn error of metabolism, Porphyria, Acute Intermittent, Cancer research, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, business, Biomarkers, autosomal dominant disease
وصف الملف: application/pdf
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المؤلفون: Lars Skjærven, Oscar Aubi, Aurora Martinez, Illimar Hugo Rekand, Marte I. Flydal, Jarl Underhaug, Huaixin Zheng, Nicholas P. Cianciotto, Bengt Erik Haug, Hanna-Kirsti S. Leiros
المصدر: Journal of Medicinal Chemistry. 58:8402-8412
مصطلحات موضوعية: Phenylalanine hydroxylase, Iron, Ligands, Legionella pneumophila, Microbiology, In vivo, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Melanins, chemistry.chemical_classification, biology, Chemistry, Drug discovery, Phenylalanine Hydroxylase, medicine.disease, biology.organism_classification, In vitro, Enzyme, Drug development, Biochemistry, biology.protein, Molecular Medicine, Legionnaires' disease, Legionnaires' Disease
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المؤلفون: Andrea Angelini, Luca Codutti, Teresa Carlomagno, Justyna Sikorska, Rebeca Saez-Ameneiro, Bettina Elshorst, Lars Skjærven, Peter Monecke
المصدر: MedChemComm. 6:1501-1507
مصطلحات موضوعية: Pharmacology, Virtual screening, Chemistry, Organic Chemistry, Pharmaceutical Science, Model system, Zinc database, Ligand (biochemistry), Biochemistry, Combinatorial chemistry, Identification (information), Drug Discovery, Molecular Medicine, Pharmacophore
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المؤلفون: Oscar Aubi, Jarl Underhaug, Marián Alonso-Mariño, David J. López, Sonia Bañuelos, María A. Urbaneja, Igor Arregi, Andoni Cuevas, Jose Antonio Rodriguez, Aurora Martinez, Lars Skjærven
المصدر: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)مصطلحات موضوعية: 0301 basic medicine, Nucleolus, Science, Mutant, Drug Evaluation, Preclinical, Intracellular Space, Article, Ribosome assembly, 03 medical and health sciences, Protein Domains, hemic and lymphatic diseases, medicine, Humans, Nucleophosmin, Multidisciplinary, integumentary system, Chemistry, Protein Stability, Myeloid leukemia, Nuclear Proteins, medicine.disease, Subcellular localization, Cell biology, High-Throughput Screening Assays, Folding (chemistry), Leukemia, Leukemia, Myeloid, Acute, Protein Transport, 030104 developmental biology, Mutation, Medicine, HeLa Cells
وصف الملف: application/pdf
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المؤلفون: Barry J. Grant, Xin-Qiu Yao, Shashank Jariwala, Lars Skjærven
المصدر: Journal of Visualized Experiments : JoVE
مصطلحات موضوعية: 0301 basic medicine, Data Interpretation, Protein family, Protein structure analysis, Computer science, General Chemical Engineering, Principal component analysis, Sequence alignment, Biomolecular structure, Protein dynamics, computer.software_genre, Biochemistry, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Protein structure, Protein sequencing, Psychology, Amino Acid Sequence, Multiple sequence alignment, General Immunology and Microbiology, General Neuroscience, Proteins, Normal mode analysis, Statistical, 030104 developmental biology, Workflow, Issue 125, Data Interpretation, Statistical, Biophysics, Programming Languages, Cognitive Sciences, Generic health relevance, Data mining, Biochemistry and Cell Biology, computer, Sequence Alignment
وصف الملف: application/pdf
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المؤلفون: Teresa Carlomagno, Peter Monecke, Dorota Latek, Andrea Angelini, Luca Codutti, Manuela Grimaldi, Matthias K. Dreyer, Lars Skjærven
المصدر: Journal of the American Chemical Society. 135:5819-5827
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular model, Protein Conformation, Chemistry, Animals, Cricetinae, Cyclic AMP-Dependent Protein Kinases, Ligands, Protein Kinase Inhibitors, Drug Design, Molecular Docking Simulation, General Chemistry, Computational biology, Biochemistry, Catalysis, Crystallography, ComputingMethodologies_PATTERNRECOGNITION, Colloid and Surface Chemistry, Protein structure, Protein–ligand docking, Searching the conformational space for docking, Docking (molecular)
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المؤلفون: Shashank Jariwala, Xin-Qiu Yao, Barry J. Grant, Lars Skjærven
المصدر: Bioinformatics
Bioinformatics (Oxford, England), vol 32, iss 22مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Data Interpretation, Source code, Bioinformatics, Computer science, media_common.quotation_subject, MEDLINE, Biochemistry, Mathematical Sciences, World Wide Web, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Software, Information and Computing Sciences, Molecular Biology, media_common, business.industry, Data interpretation, Proteins, Statistical, Biological Sciences, Interactive analysis, Applications Notes, Structural Bioinformatics, Computer Science Applications, Computational Mathematics, 030104 developmental biology, Computational Theory and Mathematics, Data Interpretation, Statistical, Programming Languages, business, Sequence Alignment, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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18Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme
المؤلفون: Romain Meyer, Aurora Martinez, Lars Skjærven, Marte I. Flydal, Petri Kursula, Maria Teresa Bezem, Anne Baumann
المصدر: Scientific Reports
Scientific reports 6(1), 30390 (2016). doi:10.1038/srep30390مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Tyrosine 3-Monooxygenase, Dopamine, Plasma protein binding, Crystal structure, Article, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, law, Catalytic Domain, Enzyme Stability, Humans, chemistry.chemical_classification, Multidisciplinary, Tyrosine hydroxylase, Small-angle X-ray scattering, 030104 developmental biology, Enzyme, chemistry, Biochemistry, Recombinant DNA, ddc:000, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Xin-Qiu Yao, Barry J. Grant, Lars Skjærven
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, Protein family, Allosteric regulation, Nanotechnology, Molecular Dynamics Simulation, Guanosine Diphosphate, Article, 03 medical and health sciences, Molecular dynamics, Hemoglobins, Protein structure, Allosteric Regulation, Heterotrimeric G protein, Materials Chemistry, Humans, Protein Interaction Domains and Motifs, Physical and Theoretical Chemistry, Caspase 7, Chemistry, Protein engineering, GTP-Binding Protein alpha Subunits, Surfaces, Coatings and Films, Range (mathematics), 030104 developmental biology, Mutation, Thermodynamics, Protein Conformation, beta-Strand, Guanosine Triphosphate, Biological system, Allosteric Site, Network analysis, Protein Binding
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المؤلفون: Heli Havukainen, Bente Smedal, Gro V. Amdam, Lars Skjærven, Øyvind Halskau
المصدر: Journal of Experimental Biology. 214:582-592
مصطلحات موضوعية: Models, Molecular, animal structures, Glycosylation, Physiology, Sequence analysis, Fat Body, Fluorescent Antibody Technique, Aquatic Science, Vitellogenins, chemistry.chemical_compound, Vitellogenin, Tandem Mass Spectrometry, Hemolymph, Animals, Homology modeling, Protein precursor, Molecular Biology, Research Articles, Ecology, Evolution, Behavior and Systematics, Base Sequence, Models, Genetic, biology, Sequence Analysis, DNA, Bees, chemistry, Biochemistry, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Insect Science, biology.protein, Female, Animal Science and Zoology, DNA
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