المؤلفون: Laetitia Furio, Georgios Pampalakis, Iacovos P Michael, Andras Nagy, Georgia Sotiropoulou, Alain Hovnanian

المصدر: PLoS Genetics, Vol 11, Iss 9, p e1005389 (2015)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4577096?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/9929a23a79d3466e848b3a4f6d7195b4

المؤلفون: Hugo, Garcia, Alice S, Serafin, Flora, Silbermann, Esther, Porée, Amandine, Viau, Clémentine, Mahaut, Katy, Billot, Éléonore, Birgy, Meriem, Garfa-Traore, Stéphanie, Roy, Salomé, Ceccarelli, Manon, Mehraz, Pamela C, Rodriguez, Bérangère, Deleglise, Laetitia, Furio, Fabienne, Jabot-Hanin, Nicolas, Cagnard, Elaine, Del Nery, Marc, Fila, Soraya, Sin-Monnot, Corinne, Antignac, Stanislas, Lyonnet, Pauline, Krug, Rémi, Salomon, Jean-Philippe, Annereau, Alexandre, Benmerah, Marion, Delous, Luis, Briseño-Roa, Sophie, Saunier

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(18)

مصطلحات موضوعية: Male, Mice, Polycystic Kidney Diseases, Prostaglandins, Animals, Humans, Receptors, Prostaglandin E, Female, Cilia, Kidney Diseases, Cystic, Ciliopathies, Zebrafish

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ced2553a94a29b1c195825aaa0a29310
https://pubmed.ncbi.nlm.nih.gov/35482924

المؤلفون: Hugo Garcia, Alice Serafin, Flora Silbermann, Esther Poree, Clémentine Mahaut, Amandine Viau, Katy Billot, Éléonore Birgy, Meriem Garfa-Traore, Stéphanie Roy, Salomé Cecarelli, Manon Mehraz, Pamela C. Rodriguez, Bérangère Deleglise, Laetitia Furio, Fabienne Jabot-Hanin, Nicolas Cagnard, Elaine Del Nery, Marc Fila, Soraya Sin-Monnot, Corinne Antignac, Stanislas Lyonnet, Pauline Krug, Rémi Salomon, Jean-Philippe Annereau, Alexandre Benmerah, Marion Delous, Luis Briseño-Roa, Sophie Saunier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1220b1f23a9be5c30f8c38126be9b93f
https://doi.org/10.1101/2022.01.21.477191

المؤلفون: Maria Brattsand, Joakim E. Swedberg, Laetitia Furio, Alain Hovnanian, Judith A. Clements, Jonathan M. Harris, Simon J. de Veer, Christopher A. Munro

المصدر: Journal of Investigative Dermatology. 137:430-439

مصطلحات موضوعية: 0301 basic medicine, Proteases, Dermatology, Biology, Biochemistry, Desquamation, 03 medical and health sciences, 0302 clinical medicine, Peptide Library, KLK7, medicine, Stratum corneum, Humans, Molecular Biology, Corneocyte, integumentary system, KLK5, Cell Biology, Kallikrein, 030104 developmental biology, medicine.anatomical_structure, LEKTI, 030220 oncology & carcinogenesis, Kallikreins, Epidermis, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafdf109aa91d3c0b32532862f651b4a
https://doi.org/10.1016/j.jid.2016.09.017

المؤلفون: Sylvie Fraitag, Laetitia de Peufeilhoux, Stéphanie Leclerc-Mercier, Nicolas Ortonne, Lisa Weibel, Laetitia Furio, Christine Bodemer, Emmanuelle Bourrat, Alain Hovnanian, Smail Hadj-Rabia, Anne-Claire Bursztejn, Thierry Jo Molina

المصدر: The American Journal of Dermatopathology. 38:83-91

مصطلحات موضوعية: 0301 basic medicine, Pathology, Biopsy, DNA Mutational Analysis, 030207 dermatology & venereal diseases, 0302 clinical medicine, Child, Skin, Aged, 80 and over, integumentary system, medicine.diagnostic_test, General Medicine, Middle Aged, Prognosis, Immunohistochemistry, Dyskeratosis, Phenotype, medicine.anatomical_structure, LEKTI, Child, Preschool, Serine Peptidase Inhibitor Kazal-Type 5, medicine.symptom, Adult, Genetic Markers, medicine.medical_specialty, Adolescent, Proteinase Inhibitory Proteins, Secretory, Dermatology, Pathology and Forensic Medicine, Young Adult, 03 medical and health sciences, Dermis, Predictive Value of Tests, medicine, Humans, Genetic Predisposition to Disease, Netherton syndrome, Parakeratosis, Aged, Retrospective Studies, business.industry, Infant, Newborn, Infant, Retrospective cohort study, medicine.disease, 030104 developmental biology, Netherton Syndrome, Mutation, Skin biopsy, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb3290cb5da55bdc21f506d793ea21b
https://doi.org/10.1097/dad.0000000000000425

المؤلفون: Anne M. van der Does, Jia Sun, Yongquan Chen, Ramine Mecheri, Birgitta Agerberth, Loredana Saveanu, Peter van Endert, Julien Diana, Erik Lundeberg, Laetitia Furio

المصدر: Immunity. 43:304-317

مصطلحات موضوعية: Male, medicine.medical_treatment, Immunology, Antimicrobial peptides, Nod, Biology, Gut flora, Cathelicidin, Immune system, Cathelicidins, Mice, Inbred NOD, Insulin-Secreting Cells, medicine, Animals, Immunology and Allergy, Pancreas, NOD mice, Mice, Knockout, Mice, Inbred BALB C, Microbiota, Pancreatic islets, Fatty Acids, Volatile, biology.organism_classification, Intestines, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, Infectious Diseases, medicine.anatomical_structure, Female, Antimicrobial Cationic Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a793fc8112f3d79c9a21541b15ac9fa7
https://doi.org/10.1016/j.immuni.2015.07.013

المؤلفون: Michèle Reboud-Ravaux, Bernard Pirotte, Xiao Tan, Jean-François Renard, Maurice Pagano, I. Kempen, Feryel Soualmia, Laetitia Furio, Lixian Qin, Alain Hovnanian, Chahrazade El Amri

المساهمون: Vieillissement Cellulaire Intégré et Inflammation (VCII), Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National pour la Recherche Medicale (INSERM), Universite Pierre et Marie Curie (UPMC), Centre National de la Recherche Scientifique (CNRS), Agence Nationale de Recherche (ANR-GENOPAT), French Ministery of Research and Education, Agence Nationale de Recherche, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (2), pp.598-612. ⟨10.1021/jm500988d⟩
Journal of Medicinal Chemistry, 2015, 58 (2), pp.598-612. ⟨10.1021/jm500988d⟩

مصطلحات موضوعية: Genetically modified mouse, Serine Proteinase Inhibitors, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Skin Diseases, Structure-Activity Relationship, In situ zymography, Coumarins, Drug Discovery, medicine, Humans, Structure–activity relationship, Netherton syndrome, Matriptase, Cytotoxicity, chemistry.chemical_classification, biology, urogenital system, Chemistry, Serine Endopeptidases, Kallikrein, medicine.disease, Molecular biology, Enzyme, Biochemistry, biology.protein, Molecular Medicine, Kallikreins, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbac76d2f5342a8dd75623981d181755
https://doi.org/10.1021/jm500988d

المؤلفون: Alain Hovnanian, Laetitia Furio

المصدر: Biological Chemistry. 395:945-958

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Clinical Biochemistry, Inflammation, Biochemistry, Pathogenesis, Hypersensitivity, medicine, Stratum corneum, Animals, Humans, Netherton syndrome, Molecular Biology, Skin, Serine protease, Protease, integumentary system, biology, business.industry, Kallikrein, medicine.disease, Dermatology, Disease Models, Animal, medicine.anatomical_structure, LEKTI, Netherton Syndrome, Immunology, biology.protein, Kallikreins, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19133e67cd77d9c2cb7279c4a59266c
https://doi.org/10.1515/hsz-2014-0137

المؤلفون: Rob J. Vreeken, M. Janssens, Joke A. Bouwstra, Walter A. Boiten, Laetitia Furio, Jeroen van Smeden, Vincent van Drongelen, Alain Hovnanian

المصدر: Journal of Investigative Dermatology. 134:1238-1245

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Lipid composition, Dermatology, Fatty Acids, Nonesterified, Ceramides, Biochemistry, Dermatitis, Atopic, Young Adult, Body Water, Internal medicine, medicine, Stratum corneum, Humans, Netherton syndrome, Child, Molecular Biology, Gene, chemistry.chemical_classification, Serine protease, biology, Fatty Acids, Fatty acid, Cell Biology, medicine.disease, Sphingomyelin Phosphodiesterase, Enzyme, Endocrinology, medicine.anatomical_structure, nervous system, chemistry, Glucosyltransferases, Netherton Syndrome, Fatty Acids, Unsaturated, biology.protein, Glucosylceramidase, Female, lipids (amino acids, peptides, and proteins), Epidermis, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213f4012ac47d53f16d4bb6da4d9d73c
https://doi.org/10.1038/jid.2013.517

المؤلفون: Laetitia Furio, Simon J. de Veer, Alain Hovnanian, Jonathan M. Harris

المصدر: PROTEOMICS - Clinical Applications. 8:389-402

مصطلحات موضوعية: Proteomics, Proteases, Corneocyte, Gene Expression Profiling, Regeneration (biology), Clinical Biochemistry, Human skin, Biology, Skin Diseases, Gene Expression Regulation, Enzymologic, Cell biology, medicine.anatomical_structure, Immune system, Immunology, medicine, Animals, Humans, Protease Inhibitors, Epidermis, Keratinocyte, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b414f7f86617a65cdadb3d635bb60f17
https://doi.org/10.1002/prca.201300081

المؤلفون: Alain Hovnanian, Akemi Ishida-Yamamoto, Elodie Tron, Valérie Malan, Masaru Honma, Laetitia Furio, Satomi Igawa, Masamoto Murakami

المصدر: Experimental Dermatology. 23:60-63

مصطلحات موضوعية: Genetics, Haplotype, Genodermatosis, Dermatology, Biology, medicine.disease, Biochemistry, Phenotype, Molecular biology, Corneodesmosin, Exon, Peeling skin syndrome, medicine, Deletion mapping, Molecular Biology, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3539fc3e76578b7f4d9cab33301ae6b1
https://doi.org/10.1111/exd.12292

المؤلفون: Lucie Lelievre, Philippe Pelissier, Hervé Lécuyer, Laetitia Furio, Olivier Join-Lambert, Xavier Nassif, Florence Miller, Anne Jamet, Alain Schmitt, Mathieu Coureuil, Sylvie Fraitag

المصدر: The Journal of Infectious Diseases. 208:1590-1597

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Endothelium, Human skin, Neisseria meningitidis, Biology, medicine.disease_cause, Bacterial Adhesion, Mice, In vivo, medicine, Animals, Humans, Immunology and Allergy, Skin, Endothelial Cells, Skin Transplantation, medicine.disease, Meningococcal Infections, Purpura, Infectious Diseases, medicine.anatomical_structure, Fimbriae, Bacterial, Purpura Fulminans, Microvessels, Immunology, Heterografts, Immunohistochemistry, Female, Endothelium, Vascular, medicine.symptom, Vasculitis, Purpura fulminans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f92753a344ebb8835201670db6b270
https://doi.org/10.1093/infdis/jit301

المؤلفون: Matteo Berretti, Laetitia Furio, Paola Fortugno, Giovanna Zambruno, Alain Hovnanian, Marina D'Alessio, May El Hachem, Massimo Teson

المصدر: Human Molecular Genetics. 21:4187-4200

مصطلحات موضوعية: Thymic stromal lymphopoietin, Mutation, Missense, Proteinase Inhibitory Proteins, Secretory, Serine Peptidase Inhibitor Kazal-Type 5, Biology, Cell Line, Dermatitis, Atopic, Mice, KLK7, Genetics, medicine, Animals, Humans, Netherton syndrome, Molecular Biology, Genetics (clinical), Desmoglein 1, Serine Endopeptidases, Proteolytic enzymes, KLK5, General Medicine, Kallikrein, medicine.disease, Molecular biology, LEKTI, Proteolysis, Immunology, Kallikreins, Epidermis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74856b369fdf67bddbf60b3700670b25
https://doi.org/10.1093/hmg/dds243

المؤلفون: Nadia Naffakh, Chris Ka Pun Mok, Hui-Ling Yen, Fany Blanc, Mustapha Si-Tahar, Michel Chignard, Emmanuel Letavernier, Laetitia Furio, Dorothée Moisy

المساهمون: Défense innée et inflammation, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), The University of Hong Kong (HKU), Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), This study was partially funded by an Institut Pasteur PTR#186 grant. F. Blanc and L. Furio were financially supported by two grants from the 'Agence Nationale de la Recherche' (FluProPar and NKTVir, respectively)., ANR-07-MIME-0010,FLUPROPAR,Etude de la modulation de l'infection grippale par les protéases et les antiprotéases de l'hôte(2007), ANR-08-MIEN-0021,NKTVIR,Etude des mécanismes d'activation et rôle des lymphocytes T Natural Killer lors des infections virales(2008), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2016, 310 (7), pp.L689-L699. ⟨10.1152/ajplung.00314.2015⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2016, 310 (7), pp.L689-L699. ⟨10.1152/ajplung.00314.2015⟩

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Gene Expression Regulation, Viral, Proteases, Physiology, Biology, medicine.disease_cause, Virus Replication, Gene Expression Regulation, Enzymologic, Proinflammatory cytokine, lung, Madin Darby Canine Kidney Cells, Pathogenesis, 03 medical and health sciences, Immune system, Dogs, Physiology (medical), Influenza, Human, Influenza A virus, medicine, Gene silencing, Animals, Humans, Influenza A Virus, H5N1 Subtype, Calpain, Epithelial Cells, Cell Biology, immunity, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Viral replication, inflammation, Receptors, Pattern Recognition, Immunology, biology.protein, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8196c90d64ab014d790253ab70f206
https://pubmed.ncbi.nlm.nih.gov/26747784

المؤلفون: Laetitia Furio, Blandine Ducarre, Odile Berthier-Vergnes, Josette Péguet-Navarro, Daniel Schmitt

المساهمون: Laviron, Nathalie

المصدر: Journal of Investigative Dermatology. 125:1032-1038

مصطلحات موضوعية: Langerhans cell, Langerin, Ultraviolet Rays, Apoptosis, Human skin, Dermatology, Biochemistry, Flow cytometry, Immune system, Dermis, Cell Movement, medicine, Humans, Antigen-presenting cell, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Molecular Biology, integumentary system, biology, medicine.diagnostic_test, Immunity, Dendritic Cells, Cell Biology, Dendritic cell, Molecular biology, Phenotype, medicine.anatomical_structure, UVA, Immunology, biology.protein, immune suppression, sense organs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b803f38e247c584f77e441c928fbf2f
https://doi.org/10.1111/j.0022-202x.2005.23904.x

المؤلفون: Pierre Charneau, Mustapha Si-Tahar, Viviane Balloy, Laurence Fiette, Michel Chignard, Julien Pothlichet, Damien Chopy, Monique Lafon, Fany Blanc, Laetitia Furio, Francina Langa

المساهمون: Défense innée et inflammation, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Neuro-Immunologie Virale, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Histotechnologie et Pathologie, Institut Pasteur [Paris], Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Virologie moléculaire et Vectorologie, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], This work was supported by the Institut Pasteur (grant PTR 186), the Agence Nationale de la Recherche (grants FluProParand NKTVir to F. B. and L. F.), and the Ministère de l’Enseignement Supérieur et de la Recherche (fellowship to D. C.), ANR-07-MIME-0010,FLUPROPAR,Etude de la modulation de l'infection grippale par les protéases et les antiprotéases de l'hôte(2007), ANR-08-MIEN-0021,NKTVIR,Etude des mécanismes d'activation et rôle des lymphocytes T Natural Killer lors des infections virales(2008), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)

المصدر: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2014, 210 (2), pp.214-23. ⟨10.1093/infdis/jiu076⟩
Journal of Infectious Diseases, 2014, 210 (2), pp.214-23. ⟨10.1093/infdis/jiu076⟩

مصطلحات موضوعية: MESH: Signal Transduction, [SDV]Life Sciences [q-bio], Gene Expression, medicine.disease_cause, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, DEAD-box RNA Helicases, Mice, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Leukocytes, Influenza A virus, Immunology and Allergy, MESH: Animals, MESH: Orthomyxoviridae Infections, 0303 health sciences, MESH: RNA Helicases, Pattern recognition receptor, 3. Good health, Infectious Diseases, MESH: Survival Analysis, Host-Pathogen Interactions, DEAD Box Protein 58, [SDV.IMM]Life Sciences [q-bio]/Immunology, Inflammation Mediators, Signal transduction, medicine.symptom, RNA Helicases, Signal Transduction, Genetically modified mouse, MESH: Gene Expression, MESH: Mice, Transgenic, Orthomyxoviridae, MESH: Inflammation Mediators, MESH: Influenza A virus, Mice, Transgenic, Inflammation, Biology, MESH: Leukocytes, 03 medical and health sciences, Immune system, Orthomyxoviridae Infections, In vivo, MESH: Mice, Inbred C57BL, medicine, Animals, MESH: DEAD-box RNA Helicases, MESH: Mice, 030304 developmental biology, MESH: Host-Pathogen Interactions, biology.organism_classification, Survival Analysis, Mice, Inbred C57BL, Disease Models, Animal, Immunology, MESH: Disease Models, Animal, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7750fc2bf1c900dde1637b7ab53be0a9
https://hal-univ-tours.archives-ouvertes.fr/hal-01117510

المؤلفون: Chahrazade El Amri, Xiao Tan, Lixian Qin, Claudia Bertonati, Laetitia Furio, Michèle Reboud-Ravaux, Bruno O. Villoutreix, Alain Hovnanian

المساهمون: Vieillissement Cellulaire Intégré et Inflammation (VCII), Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National pour la Recherche Medicale (INSERM), Universite Pierre et Marie Curie (UPMC), Agence Nationale de Recherche (grant ANR-GENOPAT), French Ministry of Research and Education, Agence Nationale de Recherche, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2013, 70, pp.661-668. ⟨10.1016/j.ejmech.2013.10.040⟩
European Journal of Medicinal Chemistry, 2013, 70, pp.661-668. ⟨10.1016/j.ejmech.2013.10.040⟩

مصطلحات موضوعية: Virtual screening, Models, Molecular, Proteases, Serine Proteinase Inhibitors, In silico, Serine Peptidase Inhibitor Kazal-Type 5, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, In vitro screening, Small Molecule Libraries, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Netherton syndrome, Matriptase, Pharmacology, Serine protease, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Reversible inhibitors, General Medicine, Kallikrein, medicine.disease, High-Throughput Screening Assays, Skin diseases, LEKTI, Biochemistry, Small organic molecules, biology.protein, Kallikreins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21f8822ea9a5ff597da852424a9117c
https://pubmed.ncbi.nlm.nih.gov/24211642

المؤلفون: Simon J. de Veer, Jonathan M. Harris, Laetitia Furio, Alain Hovnanian

المصدر: Trends in molecular medicine. 20(3)

مصطلحات موضوعية: Keratinocytes, Proteases, Human skin, Biology, Epidermal homeostasis, Skin Diseases, Signalling molecules, medicine, Homeostasis, Humans, Protease Inhibitors, Molecular Biology, Skin, chemistry.chemical_classification, integumentary system, Epidermis (botany), Processing enzymes, Cell Differentiation, Enzyme, medicine.anatomical_structure, chemistry, Immunology, Proteolysis, Molecular Medicine, Epidermis, Keratinocyte, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8800406f11030f8fb6e16792646168
https://pubmed.ncbi.nlm.nih.gov/24380647

المؤلفون: Michèle Reboud-Ravaux, Bruno O. Villoutreix, Xiao Tan, Alain Hovnanian, Chahrazade El Amri, Laetitia Furio

المساهمون: Vieillissement Cellulaire Intégré et Inflammation (VCII), Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National pour la Recherche Medicale (INSERM), Universite Pierre et Marie Curie (UPMC), Agence Nationale de Recherche (grant ANR-GENOPAT), French Ministery of Research and Education, Agence Nationale de Recherche, Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2013, 23 (16), pp.4547-4551. ⟨10.1016/j.bmcl.2013.06.039⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2013, 23 (16), pp.4547-4551. ⟨10.1016/j.bmcl.2013.06.039⟩

مصطلحات موضوعية: Keratinocytes, Cell Survival, High-throughput screening, Clinical Biochemistry, Acyl-enzymes, Pharmaceutical Science, Serine Peptidase Inhibitor Kazal-Type 5, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biochemistry, Skin Diseases, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Matriptase, Netherton syndrome, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Inhibitors, Organic Chemistry, 1,2,4-Triazole, Kallikrein, Triazoles, medicine.disease, Enzyme Activation, Enzyme, chemistry, LEKTI, Transient inactivators, biology.protein, Molecular Medicine, Kallikreins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adab1513f14ded5429e601aacb82486e
https://hal.science/hal-01543983

المؤلفون: Lucie Beaudoin, Franck J. Barrat, Agnès Lehuen, Yannick Simoni, Julien Diana, Laetitia Furio, Birgitta Agerberth

المصدر: Nature medicine. 19(1)

مصطلحات موضوعية: medicine.medical_specialty, Neutrophils, Cell, General Biochemistry, Genetics and Molecular Biology, Mice, Cathelicidins, Mice, Inbred NOD, Internal medicine, Insulin-Secreting Cells, medicine, Animals, Secretion, Receptor, Pancreas, NOD mice, B-Lymphocytes, Mice, Inbred BALB C, Innate immune system, Chemistry, Pancreatic islets, Interferon-alpha, General Medicine, Dendritic Cells, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 1, Immunoglobulin G, Toll-Like Receptor 9, Myeloid Differentiation Factor 88, Female, Beta cell, Antimicrobial Cationic Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d21d386f8a440ee5de58cd8aa31633
https://pubmed.ncbi.nlm.nih.gov/23318231