نتائج البحث - "Laddach, Anna"

المصدر: Cujba , A M , Alvarez-Fallas , M E , Pedraza-Arevalo , S , Laddach , A , Shepherd , M H , Hattersley , A T , Watt , F M & Sancho , R 2022 , ' An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function ' , Cell Reports , vol. 38 , no. 9 , 110425 . https://doi.org/10.1016/j.celrep.2022.110425

مصطلحات موضوعية: CRISPR/Cas9, diabetes, HNF1α, HNF1β, MODY3, organoid, p291fsinsC, pancreas, progenitor, β cell

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/fcfdb227-7eb6-4e85-95a5-1e5869d5e856
https://doi.org/10.1016/j.celrep.2022.110425
http://www.scopus.com/inward/record.url?scp=85125230887&partnerID=8YFLogxK

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7

Report

Multimodal single cell data integration challenge: results and lessons learned

المؤلفون: Lance, Christopher, Luecken, Malte D., Burkhardt, Daniel B., Cannoodt, Robrecht, Rautenstrauch, Pia, Laddach, Anna, Ubingazhibov, Aidyn, Cao, Zhi-Jie, Deng, Kaiwen, Khan, Sumeer Ahmad, Liu, Qiao, Russkikh, Nikolay, Ryazantsev, Gleb, Ohler, Uwe, Pisco, Angela Oliveira, Bloom, Jonathan, Krishnaswamy, Smita, Theis, Fabian J., NeurIPS 2021 Multimodal data integration competition participants

المساهمون: Biological and Environmental Science and Engineering (BESE) Division

وصف الملف: application/pdf

Relation: Lance, C., Luecken, M. D., Burkhardt, D. B., Cannoodt, R., Rautenstrauch, P., Laddach, A., Ubingazhibov, A., Cao, Z.-J., Deng, K., Khan, S., Liu, Q., Russkikh, N., Ryazantsev, G., Ohler, U., Pisco, A. O., Bloom, J., Krishnaswamy, S., & Theis, F. J. (2022). Multimodal single cell data integration challenge: results and lessons learned. https://doi.org/10.1101/2022.04.11.487796; http://hdl.handle.net/10754/686304

الاتاحة: http://hdl.handle.net/10754/686304
https://doi.org/10.1101/2022.04.11.487796

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8

Academic Journal

Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants

المؤلفون: Laddach, Anna, Fung Ng, Joseph Chi, Fraternali, Franca

المصدر: Laddach , A , Fung Ng , J C & Fraternali , F 2021 , ' Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants ' , PLoS Biology , vol. 19 , no. 4 , e3001207 . https://doi.org/10.1371/journal.pbio.3001207

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/76142346-5a3b-4f8e-abbb-c0cdb1185444
https://doi.org/10.1371/journal.pbio.3001207
http://www.scopus.com/inward/record.url?scp=85105588763&partnerID=8YFLogxK

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9

Academic Journal

Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks

المؤلفون: Chung, Sun Sook, Ng, Joseph C.F., Laddach, Anna, Thomas, N. Shaun B., Fraternali, Franca

المصدر: Chung , S S , Ng , J C F , Laddach , A , Thomas , N S B & Fraternali , F 2021 , ' Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks ' , NAR Genomics and Bioinformatics , vol. 3 , no. 1 , lqab010 . https://doi.org/10.1093/nargab/lqab010

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/8a3a83c8-614d-4e02-925d-db0473e1988f
https://doi.org/10.1093/nargab/lqab010
http://www.scopus.com/inward/record.url?scp=85123224755&partnerID=8YFLogxK

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10

Academic Journal

High-Throughput Production and Biophysical Characterization of Wild Type and Variant Titin Domains

المؤلفون: Rees, Martin, Alexandrovich, Alexander, Nikoopour, Roksana, Grover, Sarah, Laddach, Anna, Fraternali, Franca, Jungbluth, Heinz, Gautel, Mathias

المصدر: Biophysical Journal ; volume 118, issue 3, page 6a ; ISSN 0006-3495

الاتاحة: http://dx.doi.org/10.1016/j.bpj.2019.11.228
https://api.elsevier.com/content/article/PII:S0006349519311579?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006349519311579?httpAccept=text/plain

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11

Academic Journal

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.

مصطلحات موضوعية: SNV, cell adhesion, dimensionality reduction, fibronectin, genetic variation, high content imaging, iPSC, stem cell niche, stem cells, Animals, Biological Variation, Population, Cell Differentiation, Cell Line, Cell Proliferation, Humans, Induced Pluripotent Stem Cells, Mice, Phenotype, Polymorphism, Single Nucleotide, Transcriptome

وصف الملف: Print; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/292171

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/292171
https://doi.org/10.17863/CAM.39322

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12

Academic Journal

TITINdb:A computational tool to assess titin's role as a disease gene

المؤلفون: Laddach, Anna, Gautel, Mathias, Fraternali, Franca

المصدر: Laddach , A , Gautel , M & Fraternali , F 2017 , ' TITINdb : A computational tool to assess titin's role as a disease gene ' , BIOINFORMATICS , vol. 33 , no. 21 , pp. 3482-3485 . https://doi.org/10.1093/bioinformatics/btx424

وصف الملف: application/pdf

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/fe03a01b-96e9-4e41-aeb1-fbee3bc75da3
https://doi.org/10.1093/bioinformatics/btx424
https://kclpure.kcl.ac.uk/ws/files/97420906/btx424.pdf

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13

Academic Journal

An HNF1a truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonising HNF1b function

المؤلفون: Sancho, Rocio, Cujba, Ana-Maria, Alvarez Fallas, Mario, Pedraza Arevalo, Sergio, Laddach, Anna, Shepherd, Maggie H., Hattersley, Andrew T., Watt, Fiona

المصدر: Sancho , R , Cujba , A-M , Alvarez Fallas , M , Pedraza Arevalo , S , Laddach , A , Shepherd , M H , Hattersley , A T & Watt , F 2022 , ' An HNF1a truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonising HNF1b function ' , Cell Reports .

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/an-hnf1a-truncation-associated-with-maturityonset-diabetes-of-the-young-impairs-pancreatic-progenitor-differentiation-by-antagonising-hnf1b-function(dc0e4119-ce60-4afa-a160-42c7725f3f15).html

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14

Academic Journal

Regulation of intestinal immunity and tissue repair by enteric glia

المؤلفون: Progatzky, Fränze, Shapiro, Michael, Chng, Song Hui, Garcia-Cassani, Bethania, Classon, Cajsa Helena, Sevgi, Selin, Laddach, Anna, Bon-Frauches, Ana Carina, Lasrado, Reena, Rahim, Maryam, Amaniti, Eleni-Maria, Boeing, Stefan, Shah, Kathleen, Entwistle, Lewis J., Suárez-Bonnet, Alejandro, Wilson, Mark S., Stockinger, Brigitta, Pachnis, Vassilis

المصدر: Nature ; volume 599, issue 7883, page 125-130 ; ISSN 0028-0836 1476-4687

الاتاحة: http://dx.doi.org/10.1038/s41586-021-04006-z
https://www.nature.com/articles/s41586-021-04006-z.pdf
https://www.nature.com/articles/s41586-021-04006-z

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15

Book

Prediction of Protein-Protein Interactions: Looking Through the Kaleidoscope

المؤلفون: Laddach, Anna, Chung, Sun Sook, Fraternali, Franca

المصدر: Encyclopedia of Bioinformatics and Computational Biology ; page 834-848 ; ISBN 9780128114322

الاتاحة: http://dx.doi.org/10.1016/b978-0-12-809633-8.20470-6
https://api.elsevier.com/content/article/PII:B9780128096338204706?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:B9780128096338204706?httpAccept=text/plain

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16

Book

Prediction of protein-protein interactions:Looking through the kaleidoscope

المؤلفون: Laddach, Anna, Chung, Sun Sook, Fraternali, Franca

المصدر: Laddach , A , Chung , S S & Fraternali , F 2018 , Prediction of protein-protein interactions : Looking through the kaleidoscope . in Encyclopedia of Bioinformatics and Computational Biology : ABC of Bioinformatics . vol. 1-3 , Elsevier , pp. 834-848 . https://doi.org/10.1016/B978-0-12-809633-8.20470-6

مصطلحات موضوعية: Coevolution, Homology modelling, Physicochemical properties, Protein Interaction networks, Protein interfaces, Structural domains

Relation: urn:ISBN:9780128114148

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/b35267cc-8c5d-49e4-88d5-99f522d71116
https://doi.org/10.1016/B978-0-12-809633-8.20470-6
http://www.scopus.com/inward/record.url?scp=85069491829&partnerID=8YFLogxK

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17

Academic Journal

ReDisulphID: a structural bioinformatic screen for identifying redox-regulated disulphides.

المؤلفون: Coleman, Pierre¹ (AUTHOR), Laddach, Anna² (AUTHOR), Fraternali, Franca³ (AUTHOR), Burgoyne, Joseph R.¹ (AUTHOR)

المصدر: Free Radical Biology & Medicine. 2024 Supplement 1, Vol. 218, p28-28. 1p.

18

Academic Journal

Genetic variants and protein–protein interactions:a multidimensional network-centric view

المؤلفون: Laddach, Anna, Ng, Joseph Chi-Fung, Chung, Sun Sook, Fraternali, Franca

المصدر: Laddach , A , Ng , J C-F , Chung , S S & Fraternali , F 2018 , ' Genetic variants and protein–protein interactions : a multidimensional network-centric view ' , Current Opinion in Structural Biology , vol. 50 , pp. 82-90 . https://doi.org/10.1016/j.sbi.2017.12.006

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/539e61e8-415c-49d3-899b-fbd1ee8e3dff
https://doi.org/10.1016/j.sbi.2017.12.006

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