المؤلفون: Qian Lei, Xuemei Chen, Yajie Xiong, Shangdan Li, Jiaqian Wang, Hongyun He, Yihao Deng

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

مصطلحات موضوعية: Ischemic stroke, Lysosomal Ca2+, Autophagic/lysosomal dysfunction, TFEB, TRPML1, Neuroprotection, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/ed1f662750754d7a851db6903e979242

المؤلفون: Jixiang Du, Fuchen Liu, Xihan Liu, Dandan Zhao, Dongdong Wang, Hongsheng Sun, Chuanzhu Yan, Yuying Zhao

المصدر: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

مصطلحات موضوعية: TYMP, Thymidine phosphorylase, MNGIE, Lysosomal dysfunction, Nucleotide metabolism, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1479-5876

URL الوصول: https://doaj.org/article/f6f9fe20e4f746a18a38a320afa6205d

المؤلفون: Bo Wang, Ge Zhang, Yuwen Hu, Ali Mohsin, Zhimin Chen, Weijie Hao, Zhanxia Li, Wei-Qiang Gao, Meijin Guo, Huiming Xu

المصدر: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)

مصطلحات موضوعية: Adipose-derived stem cells, Obesity, Mitochondrial dysfunction, Lysosomal dysfunction, Medicine (General), R5-920, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-6512

URL الوصول: https://doaj.org/article/b8ed664eb15342dcaaf5becf44583ccb

المؤلفون: Youngil Koh, Hyemin Kim, So Young Joo, Seulki Song, Young Hoon Choi, Hyung Rae Kim, Byul Moon, Jamin Byun, Junshik Hong, Dong-Yeop Shin, Solip Park, Kwang Hyuck Lee, Kyu Taek Lee, Jong Kyun Lee, Daechan Park, Se-Hoon Lee, Jin-Young Jang, Hyunsook Lee, Jung-Ae Kim, Sung-Soo Yoon, Joo Kyung Park

المصدر: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)

مصطلحات موضوعية: Pancreatic ductal adenocarcinoma, Lysosomal dysfunction, Autophagy, Germline variants, Genetic sequencing, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1479-5876

URL الوصول: https://doaj.org/article/009bbecbecae404a8ed7c2e23cb50d90

المؤلفون: Pan Wang, Guoyu Lan, Bin Xu, Zhenwei Yu, Chen Tian, Xia Lei, Wassilios G. Meissner, Tao Feng, Ying Yang, Jing Zhang

المصدر: Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-20 (2023)

مصطلحات موضوعية: Parkinson’s disease, Astrocyte, Extracellular vesicle, α-Synuclein, Lysosomal dysfunction, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9158

URL الوصول: https://doaj.org/article/1c501912bb17437fa5c2e599026e1c67

المؤلفون: Antonio Falace, Greta Volpedo, Marcello Scala, Federico Zara, Pasquale Striano, Anna Fassio

المصدر: Cells, Vol 13, Iss 17, p 1441 (2024)

مصطلحات موضوعية: v-ATPse, lysosomal dysfunction, neurodevelopmental disorders, neurodegeneration, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/17/1441; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/32f60c75283e4f658502a0b8b17a6da6

المؤلفون: Miriam Kessi, Baiyu Chen, Langui Pan, Li Yang, Lifen Yang, Jing Peng, Fang He, Fei Yin

المصدر: Frontiers in Molecular Neuroscience, Vol 16 (2023)

مصطلحات موضوعية: CACNA1C, molecular mechanisms, mitochondrial dysfunction, lysosomal dysfunction, mitochondrial fusion, mitochondrial fission, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2023.1209760/full; https://doaj.org/toc/1662-5099

URL الوصول: https://doaj.org/article/e403969c231e4c3f979b76bccec9053e

المؤلفون: Ge Zhang, Yuli Wang, Jianhua Lin, Bo Wang, Ali Mohsin, Zhimin Cheng, Weijie Hao, Wei-Qiang Gao, Huiming Xu, Meijin Guo

المصدر: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)

مصطلحات موضوعية: Human umbilical cord mesenchymal stem cells, Cell activity, Mitochondrial dysfunction, Lysosomal dysfunction, Medicine (General), R5-920, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-6512

URL الوصول: https://doaj.org/article/e54dc65a336c4932b222fb74fd880fc9

المؤلفون: Ferreira, Inês Sofia da Silva

المساهمون: Marques, André, Vieira, Otília, RUN

مصطلحات موضوعية: Atherosclerosis, Cholesteryl hemiesters, Cholesteryl hemiazelate, Lysosomal dysfunction, Lysosomal transcription factors, Domínio/Área Científica::Engenharia e Tecnologia::Engenharia Química

وصف الملف: application/pdf

الاتاحة: http://hdl.handle.net/10362/133432

المؤلفون: Min Wei, Guangming Bao, Song Li, Zhaofei Yang, Cheng Cheng, Weidong Le

المصدر: Ecotoxicology and Environmental Safety, Vol 248, Iss , Pp 114333- (2022)

مصطلحات موضوعية: Ambient fine particulate matter (PM2.5), Autophagic-lysosomal dysfunction, Lysosomal membrane permeabilization (LMP), P62-keap1-Nrf2 signaling pathway, Ferroptosis, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651322011733; https://doaj.org/toc/0147-6513

URL الوصول: https://doaj.org/article/81673f07388d4961903780426b467d15

المؤلفون: Chen Xiang, Xiao Yousheng, Zhu Xiaolei, Yang Wenjie, Pu Jiali, Pei Zhong

المصدر: Frontiers in Aging Neuroscience, Vol 14 (2022)

مصطلحات موضوعية: mitochondrial dysfunction, lysosomal dysfunction, neurodegenerative disease, molecular mechanism, therapeutic, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.1029440/full; https://doaj.org/toc/1663-4365

URL الوصول: https://doaj.org/article/84614d31593745b283e0778705ea56b6

المؤلفون: Jonathan Frew, Haakon Berge Nygaard

المصدر: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: Frontotemporal dementia, Progranulin, R493X, Mouse model, Lysosomal dysfunction, Open field, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/08d44b116d2c4b6aa534b76e375987fe

المؤلفون: Ria Thomas, Elizabeth B. Moloney, Zachary K. Macbain, Penelope J. Hallett, Ole Isacson

المصدر: Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: GBA, LIMP2, Idiopathic PD fibroblasts, Lysosomal dysfunction, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-6606

URL الوصول: https://doaj.org/article/f1e4acd91f9f4b089c79f0c636b6d006

المؤلفون: Stefanie Smolders, Christine Van Broeckhoven

المصدر: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-28 (2020)

مصطلحات موضوعية: Parkinson’s disease, Vesicular trafficking defects, Lysosomal dysfunction, Mitochondrial dysfunction, Lysosomal storage disorder genes, Oligogenic and polygenic inheritance, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-00935-4; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/099765268acf470eb804806135520798

المؤلفون: Felipe Martelli, Natalia H Hernandes, Zhongyuan Zuo, Julia Wang, Ching-On Wong, Nicholas E Karagas, Ute Roessner, Thusita Rupasinghe, Charles Robin, Kartik Venkatachalam, Trent Perry, Philip Batterham, Hugo J Bellen

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: spinosad, oxidative stress, lipid dysregulation, neurodegeneration, antioxidant, lysosomal dysfunction, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/73812; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/51846748db3143c4a3631663c675f04a

المؤلفون: Hongmei Zhou, Hong Ling, Yunlong Li, Xuejun Jiang, Shuqun Cheng, Golamaully Mohammad Zubeir, Yinyin Xia, Xia Qin, Jun Zhang, Zhen Zou, Chengzhi Chen

المصدر: Ecotoxicology and Environmental Safety, Vol 229, Iss , Pp 113066- (2022)

مصطلحات موضوعية: Arsenite, Beclin 1, Autophagy, Lysosomal dysfunction, Neurotoxicity, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651321011787; https://doaj.org/toc/0147-6513

URL الوصول: https://doaj.org/article/58735fc14b984825b6f31a8a2bd170f7

المؤلفون: Ruz, Clara, Barrero Hernández, Francisco Javier, Pelegrina, Javier, Bandrés Ciga, Sara, Vives Montero, Francisco, Durán Ogalla, Raquel

مصطلحات موضوعية: Parkinson’s disease, Lysosomal dysfunction, Beta-glucocerebrosidase, PSAP, Cathepsin D

Relation: Ruz, C. [et al.]. Saposin C, Key Regulator in the Alpha-Synuclein Degradation Mediated by Lysosome. Int. J. Mol. Sci. 2022, 23, 12004. [https://doi.org/10.3390/ijms231912004]; https://hdl.handle.net/10481/77723

الاتاحة: https://hdl.handle.net/10481/77723
https://doi.org/10.3390/ijms231912004

المؤلفون: Ruz, Clara, Alcantud, José Luis, Vives Montero, Francisco, Arrebola Vargas, Francisco Jesús, Durán Ogalla, Raquel

مصطلحات موضوعية: LRRK2, Lysosomal dysfunction, Glucocerebrosidase, Parkinson's disease, Autophagy

Relation: Ruz, C. [et al.]. Seventy-Two-Hour LRRK2 Kinase Activity Inhibition Increases Lysosomal GBA Expression in H4, a Human Neuroglioma Cell Line. Int. J. Mol. Sci. 2022, 23, 6935. [https://doi.org/10.3390/ijms23136935]; http://hdl.handle.net/10481/76497

الاتاحة: http://hdl.handle.net/10481/76497
https://doi.org/10.3390/ijms23136935

المؤلفون: Molero-Valenzuela, Adrià, Fontova, Pere, Alonso Carrillo, Daniel, Carreira Barral, Israel, Torres, Ana Aurora, García Valverde, María, Benítez-García, Cristina, Pérez Tomás, Ricardo, Quesada Pato, Roberto, Soto Cerrato, Vanessa

مصطلحات موضوعية: Autophagy, Treatment resistance, Autophagy inhibitor, Lysosomal dysfunction, Anionophore, Lung cancer, Treatment sensitization, Medicina, Química orgánica, Medicine, Chemistry, Organic

وصف الملف: application/pdf

Relation: Cancers. 2022, V. 14, n. 14, 3387; https://doi.org/10.3390/cancers14143387; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-117610RB-I00/ES/SMALL MOLECULE TRANSMEMBRANE ANION CARRIERS FOR BIOLOGICAL APPLICATIONS; info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 (ISCIII)/PI18%2F00441/ES/EVALUACION TERAPEUTICA PRECLINICA EN CANCER DE PULMON DE INHIBIDORES DE SURVIVINA MEDIANTE LA UTILIZACION DE FORMULACIONES NANOENCAPSULADAS Y TERAPIAS COMBINADAS; info:eu-repo/grantAgreement/Junta de Castilla y León//BU067P20; http://hdl.handle.net/10259/6766

الاتاحة: http://hdl.handle.net/10259/6766
https://doi.org/10.3390/cancers14143387

المؤلفون: Ruz, Clara, Alcantud, José Luis, Vives, Francisco, Arrebola, Francisco, Hardy, John, Lewis, Patrick A, Manzoni, Claudia, Duran, Raquel

المصدر: International Journal of Molecular Sciences , 23 (13) , Article 6935. (2022)

مصطلحات موضوعية: LRRK2, lysosomal dysfunction, glucocerebrosidase, Parkinson’s disease, autophagy

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10151785/1/ijms-23-06935-v2.pdf; https://discovery.ucl.ac.uk/id/eprint/10151785/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10151785/1/ijms-23-06935-v2.pdf
https://discovery.ucl.ac.uk/id/eprint/10151785/